BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0543.0017.p (265 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KKZ0.1 B3KKZ0_9BACI Gamma-glutamyl phosphate reductase EC=1.2.... 409 e-112 B1DL86.1 B1DL86_9BACL Gamma-glutamyl phosphate reductase EC=1.2.... 362 2e-98 A1HNY4.1 A1HNY4_9FIRM Gamma-glutamyl phosphate reductase 309 2e-82 B1BC77.1 B1BC77_CLOBO Glutamate-5-semialdehyde dehydrogenase EC=... 292 2e-77 A0PXA4.1 PROA_CLONN Gamma-glutamyl phosphate reductase EC=1.2.1.41 290 1e-76 >B3KKZ0.1 B3KKZ0_9BACI Gamma-glutamyl phosphate reductase EC=1.2.1.41 Length = 415 Score = 409 bits (1051), Expect = e-112, Method: Compositional matrix adjust. Identities = 201/264 (76%), Positives = 220/264 (83%) Query: 1 LSSNRKIIEVLHRALDETAIPSQALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGSALIQN 60 LSSNRKIIEVLH A++ TA+P +ALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGS+LIQN Sbjct: 151 LSSNRKIIEVLHEAMERTALPKEALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGSSLIQN 210 Query: 61 VVLNATVPVIETGAGICHTYLDAGADPEMALSISLNAKAQRPSVCNSMETLLVHRDYAAE 120 VV+NATVPVIETGAGICHTYLDA A P+MA +IS+NAK QRPSVCNSMETLLVH +YA Sbjct: 211 VVMNATVPVIETGAGICHTYLDASARPDMAAAISINAKVQRPSVCNSMETLLVHAEYAKS 270 Query: 121 HLLPLAEAFRKIPVELRGCPETTALIPWALPAAREDFATEYNDYILNIKIVGGLDEALQH 180 HL LAEAFR+ VELRGC T IPWA A ED++TEYNDYILNIKIV LDEA++H Sbjct: 271 HLTSLAEAFRERNVELRGCQRTLEYIPWAAVATSEDYSTEYNDYILNIKIVDRLDEAIEH 330 Query: 181 IAEFSTKHSECIVTRDVGNAERFLQEVDAAAVYHNASTRFTDXXXXXXXXXXXXSTQKLH 240 I+ + TKHSECIVT + +AERFLQEVDAAAVYHNASTRFTD STQKLH Sbjct: 331 ISVYGTKHSECIVTENEDHAERFLQEVDAAAVYHNASTRFTDGFEFGFGAEIGISTQKLH 390 Query: 241 ARGPMGLPALTSSKYKIHGSGQIR 264 ARGPMGLPALTSSKY I GSGQIR Sbjct: 391 ARGPMGLPALTSSKYVIIGSGQIR 414 >B1DL86.1 B1DL86_9BACL Gamma-glutamyl phosphate reductase EC=1.2.1.41 Length = 346 Score = 362 bits (929), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 175/265 (66%), Positives = 209/265 (78%) Query: 1 LSSNRKIIEVLHRALDETAIPSQALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGSALIQN 60 L SNR+I+EVL AL TA+P A+QLIED +R+SV+EMLKLNGLLDV+IPRGG+ALI+N Sbjct: 82 LESNRRIVEVLREALASTALPQDAIQLIEDSDRASVNEMLKLNGLLDVVIPRGGAALIRN 141 Query: 61 VVLNATVPVIETGAGICHTYLDAGADPEMALSISLNAKAQRPSVCNSMETLLVHRDYAAE 120 VV NATVPVIETGAGICHT++D AD +MA I+ NAK QRPSVCNSMETL++H +A Sbjct: 142 VVENATVPVIETGAGICHTFVDESADYDMAEQIAFNAKVQRPSVCNSMETLILHEAFAKR 201 Query: 121 HLLPLAEAFRKIPVELRGCPETTALIPWALPAAREDFATEYNDYILNIKIVGGLDEALQH 180 HL +A+ F VELRG + T I A A +DFATEYNDY+LNI+IV LDEAL+H Sbjct: 202 HLQQIADRFLAANVELRGDKQATESITQAKAATEQDFATEYNDYVLNIRIVANLDEALEH 261 Query: 181 IAEFSTKHSECIVTRDVGNAERFLQEVDAAAVYHNASTRFTDXXXXXXXXXXXXSTQKLH 240 I ++STKHSECIVT + G+AERFL EVDAAAVYHNASTRFTD STQKLH Sbjct: 262 IRKYSTKHSECIVTENAGHAERFLNEVDAAAVYHNASTRFTDGFEFGFGAEIGISTQKLH 321 Query: 241 ARGPMGLPALTSSKYKIHGSGQIRG 265 ARGPMGLPALTS+K++++G+GQIRG Sbjct: 322 ARGPMGLPALTSTKFRVYGNGQIRG 346 >A1HNY4.1 A1HNY4_9FIRM Gamma-glutamyl phosphate reductase Length = 417 Score = 309 bits (791), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 157/264 (59%), Positives = 187/264 (70%) Query: 1 LSSNRKIIEVLHRALDETAIPSQALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGSALIQN 60 ++SN I +V+ RA IP A+QLIE +R +V+ +L+LN LDVIIPRG + LIQ Sbjct: 154 INSNIAITKVITRAAQAAGIPEGAIQLIETTDRQAVNALLRLNRYLDVIIPRGSAGLIQT 213 Query: 61 VVLNATVPVIETGAGICHTYLDAGADPEMALSISLNAKAQRPSVCNSMETLLVHRDYAAE 120 VV N+T+PVIETG G+CHT++DA AD MA I+ NAK RP+VCN+METLLVHR AAE Sbjct: 214 VVENSTIPVIETGIGVCHTFVDASADLAMAQEIAFNAKVSRPAVCNAMETLLVHRAIAAE 273 Query: 121 HLLPLAEAFRKIPVELRGCPETTALIPWALPAAREDFATEYNDYILNIKIVGGLDEALQH 180 L E + VELRGCPET P PA ED+ATEY D IL +K+VG L+EAL+H Sbjct: 274 FLPSALERLHQAGVELRGCPETRRYHPAVKPATDEDWATEYLDLILAVKVVGNLEEALEH 333 Query: 181 IAEFSTKHSECIVTRDVGNAERFLQEVDAAAVYHNASTRFTDXXXXXXXXXXXXSTQKLH 240 IA + T+HSE IVTRD NA RFLQEVDAAAVY NASTRFTD STQKLH Sbjct: 334 IAAYGTRHSEAIVTRDYDNARRFLQEVDAAAVYVNASTRFTDGFEFGFGAEIGISTQKLH 393 Query: 241 ARGPMGLPALTSSKYKIHGSGQIR 264 ARGPMGLP LTS KY ++G+GQIR Sbjct: 394 ARGPMGLPELTSIKYIVYGNGQIR 417 >B1BC77.1 B1BC77_CLOBO Glutamate-5-semialdehyde dehydrogenase EC=1.2.1.41 Length = 417 Score = 292 bits (748), Expect = 2e-77, Method: Compositional matrix adjust. Identities = 146/264 (55%), Positives = 183/264 (69%) Query: 1 LSSNRKIIEVLHRALDETAIPSQALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGSALIQN 60 + SN I +++ A + +P A+ IE P+R +V+ M+KLNG +DV+IPRGG+ LI Sbjct: 154 IHSNSTIAKIISDAGVKAGLPEGAINFIETPSRDAVNIMMKLNGYIDVLIPRGGAGLINA 213 Query: 61 VVLNATVPVIETGAGICHTYLDAGADPEMALSISLNAKAQRPSVCNSMETLLVHRDYAAE 120 VV NATVPVIETG G CH Y+DA AD EMA +I +NAK QRPSVCN+ME+LLVH+D A + Sbjct: 214 VVKNATVPVIETGTGNCHVYVDASADLEMAANIVINAKTQRPSVCNAMESLLVHKDIADK 273 Query: 121 HLLPLAEAFRKIPVELRGCPETTALIPWALPAAREDFATEYNDYILNIKIVGGLDEALQH 180 L LAE + + VE++GC T +L+ A A EDFA E+ D+ K+V LDEAL H Sbjct: 274 FLPYLAEKLKPLNVEIKGCKRTQSLVESATEATEEDFAKEFLDFKFASKVVDSLDEALDH 333 Query: 181 IAEFSTKHSECIVTRDVGNAERFLQEVDAAAVYHNASTRFTDXXXXXXXXXXXXSTQKLH 240 I ++STKHSE IVT + N++RFL EVDAAAVY NAS+RFTD STQKLH Sbjct: 334 IYKYSTKHSEVIVTNNYENSQRFLNEVDAAAVYVNASSRFTDGSEFGFGAEIGISTQKLH 393 Query: 241 ARGPMGLPALTSSKYKIHGSGQIR 264 ARGPMGL LTSSKY I+G GQ R Sbjct: 394 ARGPMGLKELTSSKYIIYGEGQTR 417 >A0PXA4.1 PROA_CLONN Gamma-glutamyl phosphate reductase EC=1.2.1.41 Length = 417 Score = 290 bits (742), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 143/264 (54%), Positives = 185/264 (70%) Query: 1 LSSNRKIIEVLHRALDETAIPSQALQLIEDPNRSSVDEMLKLNGLLDVIIPRGGSALIQN 60 ++SN + ++ A + +P A+ LIE+P+R +V+ M+KLN +DV+IPRGG+ LI Sbjct: 154 INSNTTVARIISEAATKAGLPEGAINLIENPSRDAVNVMMKLNDYIDVLIPRGGAGLINA 213 Query: 61 VVLNATVPVIETGAGICHTYLDAGADPEMALSISLNAKAQRPSVCNSMETLLVHRDYAAE 120 VV NATVPVI+TG G CH ++DA AD EMA +I +NAK QRP+VCN+ME+LLVH+D A + Sbjct: 214 VVKNATVPVIQTGVGNCHVFVDASADLEMAANIVINAKTQRPAVCNAMESLLVHKDIADK 273 Query: 121 HLLPLAEAFRKIPVELRGCPETTALIPWALPAAREDFATEYNDYILNIKIVGGLDEALQH 180 L LAE + + VE++GC T +L+ A A ED+A EY D+ K+V LDEAL H Sbjct: 274 FLPYLAEKLKPLNVEIKGCIRTQSLVEGATEATEEDWAKEYLDFKFASKVVDSLDEALDH 333 Query: 181 IAEFSTKHSECIVTRDVGNAERFLQEVDAAAVYHNASTRFTDXXXXXXXXXXXXSTQKLH 240 I ++STKHSE IVT + N++RFL EVDAAAVY NAS+RFTD STQKLH Sbjct: 334 IYKYSTKHSEVIVTNNYENSQRFLAEVDAAAVYVNASSRFTDGSEFGFGAEIGISTQKLH 393 Query: 241 ARGPMGLPALTSSKYKIHGSGQIR 264 ARGPMGL LTSSKY I+G GQIR Sbjct: 394 ARGPMGLKELTSSKYIIYGEGQIR 417 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,415,623,904 Number of extensions: 53623432 Number of successful extensions: 130140 Number of sequences better than 1.0e-05: 1528 Number of HSP's gapped: 128895 Number of HSP's successfully gapped: 1537 Length of query: 265 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 132 Effective length of database: 1,807,701,208 Effective search space: 238616559456 Effective search space used: 238616559456 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 130 (54.7 bits)