BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0542.0014.p (573 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DAU0.1 B1DAU0_9BACL Integral membrane sensor signal transducti... 674 0.0 B1DGY1.1 B1DGY1_9BACL Histidine kinase internal region 176 4e-42 B1DFX0.1 B1DFX0_9BACL Histidine kinase internal region 175 1e-41 Q65KZ4.1 Q65KZ4_BACLD YesM 173 5e-41 C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein 170 3e-40 >B1DAU0.1 B1DAU0_9BACL Integral membrane sensor signal transduction histidine kinase Length = 593 Score = 674 bits (1738), Expect = 0.0, Method: Compositional matrix adjust. Identities = 346/567 (61%), Positives = 422/567 (74%), Gaps = 4/567 (0%) Query: 1 LGYVILIFIPVVVFGYYYYSQIYGNLTNQFVQSRQKILEQAHANMKMDLTRIDSIQRMLQ 60 LGYVI+IFIPV+ FGY+YY+QIYGNLT QFV+SRQKILEQA+ANMK D RI S+ R+LQ Sbjct: 9 LGYVIMIFIPVIAFGYHYYTQIYGNLTQQFVESRQKILEQAYANMKTDFARIQSVHRVLQ 68 Query: 61 YNPYVTDYLNGVYESDSHSIYAYNRYISPVITQSLFINPEIESFRIYKTKQRVLPITDRF 120 YNPY+TDYL+GVY+SD+ S+YA RYI P+ +QS+F NPEIES IYK K RVLPIT+ F Sbjct: 69 YNPYLTDYLDGVYDSDADSVYALTRYILPLYSQSMFANPEIESIVIYKMKDRVLPITNLF 128 Query: 121 LDMSSLNPQGQEVAHTLKPGQGIWMLTDPGAAVPSLMFYQNIYNSDFTEKIGILELRVGS 180 D S L+PQ + +LK GQGIW+ DP + P L++YQ IYN+ TE+IG+LE+RV + Sbjct: 129 RDRSMLDPQTEATVSSLKAGQGIWLRADPNVSEPDLIYYQYIYNTQITERIGLLEIRVSN 188 Query: 181 SLIGKLYEAAGGRDNWQAFLLPEQGVPPAEGAPAGIDKATWKLLGSKDARPYFINNKTIV 240 SLI Y AAG NW+A L+ QG A AG+D T LL + R +FI+ TIV Sbjct: 189 SLIRNFYAAAGVEGNWKAALMSGQGNLLTNEA-AGLDHKTLSLLHEQ-GRDFFIDRTTIV 246 Query: 241 NQLYIEELXXXXXXXXXXXXXFRTIKRKEIILVFTIIALLAVLSFVYYALASTITKRILL 300 NQL +E L FR++K+KEI+LV I+ LL LS YY LASTITKRIL Sbjct: 247 NQLKLEPLDVRVIITAQVGEVFRSVKQKEIVLVTIIVLLLLTLSIAYYLLASTITKRILR 306 Query: 301 LARHMRNLDDDNMKQFISKHDKPNHLDEIGFLTSTYNSMIRRMDELINNVHRSELRNKEA 360 LARHMR L+DDN++ + K DEIGFL YNSM+RRMDELINNVHR+ELRNKEA Sbjct: 307 LARHMRTLNDDNLRVLTIQSGKFEK-DEIGFLIGAYNSMVRRMDELINNVHRAELRNKEA 365 Query: 361 AYKVLQAQIKPHFLYNTLETIRMLAESNNDKEVADISFWFGKLMRYSLSSEGDRTVLARE 420 AY+VLQAQIKPHFLYNTLETIRM+AE+NNDKEVADISFWFGKLMRYSL+S TVLA+E Sbjct: 366 AYQVLQAQIKPHFLYNTLETIRMVAEANNDKEVADISFWFGKLMRYSLTSAQQETVLAKE 425 Query: 421 IETVVFYLNIHKMRLQHRLTYEIDVAMDAEQLDCPRFMLQPLVENSIVHGASAILRPVHI 480 IE V FY++IHKMRLQ RLTYEI V +DA +L CPRF+LQPL+ENSIVHGASA+LRPVHI Sbjct: 426 IEMVDFYMSIHKMRLQSRLTYEIKVDLDAGRLACPRFLLQPLIENSIVHGASAVLRPVHI 485 Query: 481 KLQVRETGDEIRISITDNGTGIQEDKLLAIRSQLARGDDNRAAAENGGGVGLFNVSERIK 540 +L ET +E+ I + DNG GI D+LL +R +L+R D+ + E GVGL NV+ER+K Sbjct: 486 RLHASETEEEVTIDVNDNGNGIAPDRLLELRDRLSRHDEFKKEDE-PVGVGLKNVNERVK 544 Query: 541 SFFGGSSQLVIDSEQDRGTCLSIIISK 567 +FG S+L I S+ +GT L I+I K Sbjct: 545 GYFGAESRLEIISDPGKGTSLRIVIVK 571 >B1DGY1.1 B1DGY1_9BACL Histidine kinase internal region Length = 597 Score = 176 bits (447), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 109/296 (36%), Positives = 161/296 (54%), Gaps = 17/296 (5%) Query: 278 ALLAVLSFVYYALASTI------TKRILLLARHMRNLDDDNMKQFISKHDKPNHLDEIGF 331 +L+ L+F A+A+++ T+ I+ L + M+ ++ N + I + DEIG Sbjct: 302 SLITALAFAIVAIAASVLIAYITTRPIIRLTQSMKAVEIQNFEVDI----REPRSDEIGT 357 Query: 332 LTSTYNSMIRRMDELINNVHRSELRNKEAAYKVLQAQIKPHFLYNTLETIRMLAESNNDK 391 L +NSM+ R+ ELI +++ + + A K +QAQI PHFL+N L+ I +A S N Sbjct: 358 LERRFNSMLSRIKELIQTEYKATIEKRTAQVKAMQAQINPHFLHNALQAIGGIALSRNVP 417 Query: 392 EVADISFWFGKLMRYSLSSEGDRTVLAREIETVVFYLNIHKMRLQHRLTYEIDVAMDAEQ 451 E+ D L RY++ + D +A E+E YL I K+R Q + ID D E Sbjct: 418 EINDHVRAISDLFRYTIRMKSDLVTIADELEHARNYLQIQKLRFQSMIEIRIDA--DEEC 475 Query: 452 LDC--PRFMLQPLVENSIVHGASAILRPVHIKLQVRETGDEIRISITDNGTGIQEDKLLA 509 L C P+F LQP+VEN VHG + I ++V + DEI I I DNG GI E +L Sbjct: 476 LGCRIPKFSLQPIVENCFVHGLEGKMDAWTISIRVEKVLDEIEIDIADNGMGIDEARLAE 535 Query: 510 IRSQLARGDDNRAAAENGGGVGLFNVSERIKSFFGGSSQLVIDSEQDRGTCLSIII 565 IR QL++ D + ENG G+G+ NV+ RIK FG L I SE + GT + ++I Sbjct: 536 IRRQLSQPADGQ---ENGEGMGISNVNARIKLLFGDEYGLFISSEWNAGTTVKLLI 588 >B1DFX0.1 B1DFX0_9BACL Histidine kinase internal region Length = 590 Score = 175 bits (444), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 102/296 (34%), Positives = 168/296 (56%), Gaps = 22/296 (7%) Query: 270 IILVFTIIALLAVLSFVYYALASTITKRILLLARHMRNLDDDNMKQFISKHDKPNHL-DE 328 + LV +I+LL ++ F + +++R+ L RHM N+ D M +P+H DE Sbjct: 293 VCLVCVLISLLMMMIF-----SERLSRRLKQLVRHMANIRDGRMA-----APEPDHTGDE 342 Query: 329 IGFLTSTYNSMIRRMDELINNVHRSELRNKE-------AAYKVLQAQIKPHFLYNTLETI 381 IG L + +MI R++ELI+ V++ ++ K+ A + LQ+QI PHFL+NT+E+I Sbjct: 343 IGELNRGFRNMIHRINELISEVYQQDIERKQLIIEKQDAELRALQSQINPHFLFNTMESI 402 Query: 382 RMLAESNNDKEVADISFWFGKLMRYSLSSEGDRTVLAREIETVVFYLNIHKMRLQHRLTY 441 RM D E ADI F KL R S+ + +A+E + + Y+ + K+R + +L + Sbjct: 403 RMTLVKKRDTETADIVASFSKLFRQSMDWRSEWNTIAQEADFISHYIRVLKLRFRDKLQF 462 Query: 442 EIDVAMDAEQLDCPRFMLQPLVENSIVHGASAILRPVHIKLQVRETGDEIRISITDNGTG 501 ++ + DA+QL+ P+F LQPL+EN+IVH + I L+V+ G+ IRI+I D+ G Sbjct: 463 KMQIDEDAQQLELPKFTLQPLIENAIVHSIERRIEGGCISLKVQMAGERIRIAICDDSPG 522 Query: 502 IQEDKLLAIRSQLARGDDNRAAAENGGGVGLFNVSERIKSFFGGSSQLVIDSEQDR 557 ++L+ I +LA+ A+ + +GL NV R+ + FG + L I+SE R Sbjct: 523 FSPERLIEITDRLAQS----ASVKTSERIGLLNVHLRLVAVFGQEAGLRIESEPGR 574 >Q65KZ4.1 Q65KZ4_BACLD YesM Length = 578 Score = 173 bits (438), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 97/296 (32%), Positives = 161/296 (54%), Gaps = 10/296 (3%) Query: 270 IILVFTIIALLAVLSFVYYALASTITKRILLLARHMRNLDDDNMKQFISKHDKPNHLDEI 329 +I +F + L+AVL +A IT I L M+N+ + + K + DE+ Sbjct: 287 LISLFILFFLIAVL--FGRKMARGITSPIEKLVAAMKNVQNGDFKLAPLTRAPLDRQDEV 344 Query: 330 GFLTSTYNSMIRRMDELINNVHRSELRNKEAAYKVLQAQIKPHFLYNTLETIRMLAESNN 389 L + +M+ R++ELI ++ +L KE +K LQAQI PHFLYNTLE+I LA++N Sbjct: 345 SVLNRNFFTMVERINELIAENYKKQLMLKETEFKALQAQINPHFLYNTLESINWLAKTNR 404 Query: 390 DKEVADISFWFGKLMRYSLSSEGDRTVLAREIETVVFYLNIHKMRLQHRLTYEIDVAMDA 449 +++ ++ G L+R +++ + D + E E V Y I + R + RL +E+D+ Sbjct: 405 QPQISKMTESLGFLLRNAINMKTDVLTIEEEAEIVRHYFTIQRFRFEERLVFELDIEPAV 464 Query: 450 EQLDCPRFMLQPLVENSIVHGASAILRPVHIKLQVRETGDEIRISITDNGTGIQEDKLLA 509 ++ P+ +LQPL EN+I + + P HI+++ + + + +++ DNG G+ ED L Sbjct: 465 KKCRVPKLVLQPLAENAITYCLEPFIEPCHIQIKAYKKEELVYLTVADNGPGMDEDFLEK 524 Query: 510 IRSQLARGDDNRAAAENGGGVGLFNVSERIKSFFGGSSQLVIDSEQDRGTCLSIII 565 R +L R G G+GL N+ ERI+ FG L I SE+++GT + I I Sbjct: 525 ARKELVR--------TTGRGIGLQNIDERIQLMFGKGYGLTISSEKNKGTVMMIKI 572 >C0C1J1.1 C0C1J1_9CLOT Putative uncharacterized protein Length = 601 Score = 170 bits (431), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 142/597 (23%), Positives = 270/597 (45%), Gaps = 52/597 (8%) Query: 1 LGYVILIFIPVVVFGYYYYSQIYGNLTNQFVQSRQKILEQAHANMKMDLTRIDSIQRMLQ 60 +G++++I + V + GY+ + ++ Q + S Q+ + Q N++ ++ ++ + + Sbjct: 17 IGFILVIAVLVSLLGYFSMTFSEQSIRTQMLDSIQETMNQMGENIEGEIQKVLDVSAQVC 76 Query: 61 YNPYVTDYLNGVYESDSHSIYAYNRYISPVITQSLFINPEIESF-------RIYKTKQRV 113 N + L Y+ ++ + ++ +S +E +Y + + Sbjct: 77 LNEELCTVLQEEKPGTIEEYYSKDKTMRQILNESYAAYFSVEDVFVCSYNGSVYGSDKNK 136 Query: 114 LPITDRFLDMSSLNPQGQEVAHTLKPGQGIWMLT--DPGAAV----PSLMF--YQNIYNS 165 L +T + D + A + G G+ +L+ D + + P +F + IYN Sbjct: 137 LSLTADY-DFTRTGW----FADMKQSGAGVSILSQYDSSSYISTGEPQKLFSIVKKIYNY 191 Query: 166 DFTEKIGILELRVGSSLIGKLYEAAGGRDNWQAFLL---------PEQ---GVPPAEGAP 213 ++IG L + + S ++G + ++ + Q ++ P+ G E Sbjct: 192 RSGKEIGCLIVHMNSDILGNVLQSVNSNEYQQCLIIDNNKKIIYHPDSDYIGTQYREARV 251 Query: 214 AGIDKATWKLLGSKDARPYFINNKTIVNQLYIEELXXXXXXXXXXXXXFRTIKRKEIILV 273 + + + S + Y + + + V + +I R + L+ Sbjct: 252 SELLTMENGYMESLSEKGYLVFSTSAVTGWSV-------ISVVDNKYIMDSINRLRLFLI 304 Query: 274 FTIIALLAVLSFVYYA--LASTITKRILLLARHMRNLDDDNMKQFISKHDKPNHLDEIGF 331 T A+ V+ VY+A ++ TI+ + L R M + + + DEIG Sbjct: 305 LT--AVFCVVLSVYFASYISKTISDPVARLQRKMYQVGEGDF----DIRAATGASDEIGQ 358 Query: 332 LTSTYNSMIRRMDELINNVHRSELRNKEAAYKVLQAQIKPHFLYNTLETIRMLAESNNDK 391 LT +++ M+ R +LI NV++SE+ KEA LQAQI PHFLYNTL+TI M+AE Sbjct: 359 LTLSFDKMVERTKQLIENVYQSEIYQKEAELNALQAQINPHFLYNTLQTIDMMAEEEGAD 418 Query: 392 EVADISFWFGKLMRYSLSSEGDRTVLAREIETVVFYLNIHKMRLQHRLTYEIDVAMDAEQ 451 E++D K+ RYS++ + + EI + Y+ I K+R +L D+ + + Sbjct: 419 EISDACQALSKIFRYSINRGQEFVHVQDEIVHIENYMLIQKLRFGGKLEVRYDIQNECRE 478 Query: 452 LDCPRFMLQPLVENSIVHGASAILRPVHIKLQVRETGDEIRISITDNGTGIQEDKLLAIR 511 L + ++QP+VEN++VHG +L ++ ++V D + + DNGTGI +L+ + Sbjct: 479 LYIVKLLIQPMVENAVVHGMENVLDKCYVTIRVYRKEDCLYAEVEDNGTGIAPGQLMELN 538 Query: 512 SQLARGDDNRAAAE-----NGGGVGLFNVSERIKSFFGGSSQLVIDSEQDRGTCLSI 563 +LAR + + E N +GL N + RIK +FG + I SE+ GT + I Sbjct: 539 EKLARSAEQKMVHEVDYVKNHRSIGLENTNARIKLYFGQEYGITITSEEGTGTKVCI 595 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.138 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,279,727,839 Number of extensions: 136237947 Number of successful extensions: 376995 Number of sequences better than 1.0e-05: 2008 Number of HSP's gapped: 374622 Number of HSP's successfully gapped: 2008 Length of query: 573 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 432 Effective length of database: 1,732,333,088 Effective search space: 748367894016 Effective search space used: 748367894016 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)