BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0052.p (224 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z7I2.1 C0Z7I2_BREBN Putative cobalt-precorrin-8X methylmutase 299 2e-79 O87692.1 O87692_BACME CbiC protein 291 4e-77 C5DAN7.1 C5DAN7_9BACI Precorrin-8X methylmutase CbiC/CobH 283 1e-74 B7GLT6.1 B7GLT6_ANOFW Precorrin isomerase 280 1e-73 B4BMM6.1 B4BMM6_9BACI Precorrin-8X methylmutase CbiC/CobH 273 6e-72 >C0Z7I2.1 C0Z7I2_BREBN Putative cobalt-precorrin-8X methylmutase Length = 216 Score = 299 bits (765), Expect = 2e-79, Method: Compositional matrix adjust. Identities = 142/198 (71%), Positives = 172/198 (86%) Query: 1 MEFGTDFKPLTVQPQEIEGLSFQMITRELGDHEFSALQYPVVQRIIHASADFELGRSLVF 60 M+F T+FKP+TVQPQEIE LSFQ+IT ELG+H F+ QYPVVQR+IHASADF+LGRSLVF Sbjct: 1 MDFKTEFKPMTVQPQEIEDLSFQIITDELGEHSFTEEQYPVVQRVIHASADFDLGRSLVF 60 Query: 61 HPRAMEAGISAILEGQPIIADVRMVEAGIAKERIHKYGGEVRVHISDPDVMEAAKAQGTT 120 HP A+++GI AI G+ ++ADV+MV+ GI+K RI K+GGEV+V+ISD DVME AK TT Sbjct: 61 HPDAVKSGIEAIRSGKIVVADVQMVQVGISKNRIEKFGGEVKVYISDRDVMEEAKRLNTT 120 Query: 121 RAILATRKACAEAPGGIYVIGNAPTALLELIRLIKEGAAQPGLIIGMPVGFVSAAESKDE 180 RAI++ RKA EA GGI+ IGNAPTALLELIR++KEG A+PGL+IGMPVGFVSAAESK+E Sbjct: 121 RAIISMRKAIKEADGGIFCIGNAPTALLELIRMVKEGEAKPGLVIGMPVGFVSAAESKEE 180 Query: 181 LRKLDIPYITNIGRKGGS 198 L KLDIP+ITN+GRKGGS Sbjct: 181 LAKLDIPFITNMGRKGGS 198 >O87692.1 O87692_BACME CbiC protein Length = 225 Score = 291 bits (744), Expect = 4e-77, Method: Compositional matrix adjust. Identities = 139/199 (69%), Positives = 169/199 (84%) Query: 1 MEFGTDFKPLTVQPQEIEGLSFQMITRELGDHEFSALQYPVVQRIIHASADFELGRSLVF 60 M+F T+FKPLTVQPQ+IEG SF+MIT ELG H F+ QYP+VQR+IH SADFELGRS++F Sbjct: 1 MDFRTEFKPLTVQPQQIEGKSFEMITEELGPHPFTDEQYPIVQRVIHRSADFELGRSMLF 60 Query: 61 HPRAMEAGISAILEGQPIIADVRMVEAGIAKERIHKYGGEVRVHISDPDVMEAAKAQGTT 120 HP A++AGI AI G+ ++ADV+MV+ G K+RI K+GGE++V+ISD DVME AK TT Sbjct: 61 HPDAIQAGIKAIRSGKQVVADVQMVQVGTNKQRIEKHGGEIKVYISDSDVMEEAKRLNTT 120 Query: 121 RAILATRKACAEAPGGIYVIGNAPTALLELIRLIKEGAAQPGLIIGMPVGFVSAAESKDE 180 RAI++ RKA EA GGI+ IGNAPTALLELIRLIKEG A+PGL+IG+PVGFVSAAESK+E Sbjct: 121 RAIISMRKAIKEADGGIFAIGNAPTALLELIRLIKEGEAKPGLVIGLPVGFVSAAESKEE 180 Query: 181 LRKLDIPYITNIGRKGGST 199 L KL +P+ITNIGRKGGST Sbjct: 181 LAKLYVPFITNIGRKGGST 199 >C5DAN7.1 C5DAN7_9BACI Precorrin-8X methylmutase CbiC/CobH Length = 215 Score = 283 bits (723), Expect = 1e-74, Method: Compositional matrix adjust. Identities = 135/199 (67%), Positives = 167/199 (83%) Query: 1 MEFGTDFKPLTVQPQEIEGLSFQMITRELGDHEFSALQYPVVQRIIHASADFELGRSLVF 60 M+F T+F+P+TVQPQ+IE SFQ+I E+G+H F+ QYP+VQR+IHASADFELG+SL+F Sbjct: 1 MDFRTEFRPITVQPQQIEERSFQIIDEEIGEHHFTKEQYPIVQRVIHASADFELGKSLLF 60 Query: 61 HPRAMEAGISAILEGQPIIADVRMVEAGIAKERIHKYGGEVRVHISDPDVMEAAKAQGTT 120 HP A+ AGI AI G+ ++ADV+MV+ G+ K RI K+GG+V+V+ISD DV+ AK TT Sbjct: 61 HPDAVRAGIEAIRSGKTVVADVQMVQVGVNKVRIEKFGGKVKVYISDEDVIAEAKRLNTT 120 Query: 121 RAILATRKACAEAPGGIYVIGNAPTALLELIRLIKEGAAQPGLIIGMPVGFVSAAESKDE 180 RAI+A RKA EA GGI+ IGNAPTALLELIRLIKEG A+PGL+IG+PVGFVSAAESK E Sbjct: 121 RAIVAMRKAAKEAEGGIFAIGNAPTALLELIRLIKEGEARPGLVIGLPVGFVSAAESKAE 180 Query: 181 LRKLDIPYITNIGRKGGST 199 L KLD+P+ITNIGRKGGST Sbjct: 181 LAKLDVPFITNIGRKGGST 199 >B7GLT6.1 B7GLT6_ANOFW Precorrin isomerase Length = 210 Score = 280 bits (715), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 135/193 (69%), Positives = 163/193 (84%) Query: 7 FKPLTVQPQEIEGLSFQMITRELGDHEFSALQYPVVQRIIHASADFELGRSLVFHPRAME 66 F+P+TVQP++IE SFQ+I E+G+H FS QY VVQR+IHASADFELG+SL+FHPRA+E Sbjct: 2 FRPITVQPEQIEQKSFQIIDEEIGEHAFSEEQYAVVQRVIHASADFELGKSLLFHPRAIE 61 Query: 67 AGISAILEGQPIIADVRMVEAGIAKERIHKYGGEVRVHISDPDVMEAAKAQGTTRAILAT 126 AG++AI G+ I+ADV+MV+ GI K RI KYGG V V+ISD DV++ AK TTRAI+A Sbjct: 62 AGVAAIRAGKKIVADVQMVQVGINKARIEKYGGSVHVYISDEDVIKEAKRLNTTRAIVAM 121 Query: 127 RKACAEAPGGIYVIGNAPTALLELIRLIKEGAAQPGLIIGMPVGFVSAAESKDELRKLDI 186 RKA EA GGI+ IGNAPTALLELIRL+KEG A+P LIIG+PVGFVSAAESK+EL KLD+ Sbjct: 122 RKAVQEAEGGIFAIGNAPTALLELIRLVKEGEARPSLIIGLPVGFVSAAESKEELAKLDV 181 Query: 187 PYITNIGRKGGST 199 P+ITNIGRKGGST Sbjct: 182 PFITNIGRKGGST 194 >B4BMM6.1 B4BMM6_9BACI Precorrin-8X methylmutase CbiC/CobH Length = 215 Score = 273 bits (699), Expect = 6e-72, Method: Compositional matrix adjust. Identities = 131/199 (65%), Positives = 164/199 (82%) Query: 1 MEFGTDFKPLTVQPQEIEGLSFQMITRELGDHEFSALQYPVVQRIIHASADFELGRSLVF 60 M+F T F+P TVQP++IE SFQ+I E+G+H F+ QY +VQR+IHASADFELG+SL+F Sbjct: 1 MDFHTTFRPATVQPEQIEARSFQIIDEEIGEHSFTEEQYRIVQRVIHASADFELGKSLIF 60 Query: 61 HPRAMEAGISAILEGQPIIADVRMVEAGIAKERIHKYGGEVRVHISDPDVMEAAKAQGTT 120 HP A+ +GI AI G+ ++ADV+MV+AG+ + R+ K+GG VRV+ISD DV+ AK TT Sbjct: 61 HPDAIRSGIDAIRSGKLVVADVQMVQAGVNQARLAKFGGAVRVYISDEDVIAEAKRLNTT 120 Query: 121 RAILATRKACAEAPGGIYVIGNAPTALLELIRLIKEGAAQPGLIIGMPVGFVSAAESKDE 180 RAI+A RKA EA GGI+ IGNAPTALLELIRLIKEG A+PGL+IG+PVGFVSAAESK+E Sbjct: 121 RAIVAMRKAVKEAEGGIFAIGNAPTALLELIRLIKEGEARPGLVIGLPVGFVSAAESKEE 180 Query: 181 LRKLDIPYITNIGRKGGST 199 L KLD+P+ITN GRKGGST Sbjct: 181 LAKLDVPFITNRGRKGGST 199 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.137 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,213,268,389 Number of extensions: 47008626 Number of successful extensions: 122258 Number of sequences better than 1.0e-05: 610 Number of HSP's gapped: 121411 Number of HSP's successfully gapped: 610 Length of query: 224 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 93 Effective length of database: 1,826,543,238 Effective search space: 169868521134 Effective search space used: 169868521134 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)