BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0051.p (297 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C5DAN8.1 C5DAN8_9BACI Cobalamin biosynthesis protein CbiD 347 1e-93 Q5KZ00.1 CBID_GEOKA Putative cobalt-precorrin-6A synthase [deace... 340 1e-91 C3J3E1.1 C3J3E1_9BACI Cobalamin biosynthesis protein CbiD 340 1e-91 B7Y6K0.1 B7Y6K0_9BACI Cobalamin biosynthesis protein CbiD 340 1e-91 B4BMM7.1 B4BMM7_9BACI Cobalamin biosynthesis protein CbiD 337 8e-91 >C5DAN8.1 C5DAN8_9BACI Cobalamin biosynthesis protein CbiD Length = 365 Score = 347 bits (889), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 167/293 (56%), Positives = 208/293 (70%) Query: 1 VKDAGDDPDATHQARIEAAVSWRDSPGVEIDGGKGVGRVTKPGLPVAVGEAAINPVPRRM 60 +KD GDDPDATH A I + VSW + PG+ +DGGKGVGRVTKPGLPV VGEAAINP+PR+M Sbjct: 66 IKDGGDDPDATHGAAIVSTVSWAEQPGIHLDGGKGVGRVTKPGLPVPVGEAAINPIPRKM 125 Query: 61 ILEAVSEVLEEHGAARGVRVVISVPEGEAIALKTLNPRXXXXXXXXXXXTRGVVTPFSTE 120 I E EVLE++G +RGV V+ISVP GE IA KTLN R TRG+V PFST Sbjct: 126 IHETAREVLEQYGISRGVNVIISVPNGEEIAKKTLNARLGIIGGISILGTRGIVIPFSTS 185 Query: 121 AYKXXXXXXXXXXXXMGNKQIILTTGGSSEKYAMAMFAELPEEAFIQMGEYVGFSLEHAK 180 AY+ G +++TTGG SEK+AM + LPEEAFI+MG++VGF+L+ K Sbjct: 186 AYRASIIQAIQVAKANGCDHVVITTGGRSEKFAMRQYPHLPEEAFIEMGDFVGFTLKQCK 245 Query: 181 AFGVRKITLVGMAGKFSKVAQGAMLIHSKNAPVDFSFLAKIAAESGADNELVGEIAAANT 240 G+R +++VGM GKFSKVAQG M++HSK+AP+DFSFLA IA ++GA ELV + ANT Sbjct: 246 RLGIRTVSMVGMMGKFSKVAQGIMMVHSKSAPIDFSFLAAIAEQAGASPELVAAVREANT 305 Query: 241 ASQVTDLMTAAGNGVFFEQLCLHACRHCLKHMNGGMTVEMVLVTMKGRVLGRA 293 ASQV ++M AGN FFE LC H C L+ + GGMTVE L TM G++LG+A Sbjct: 306 ASQVGEMMQEAGNERFFEILCDHCCLSALREVGGGMTVETSLYTMGGQLLGKA 358 >Q5KZ00.1 CBID_GEOKA Putative cobalt-precorrin-6A synthase [deacetylating] EC=2.1.1.- Length = 372 Score = 340 bits (872), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 168/293 (57%), Positives = 207/293 (70%) Query: 1 VKDAGDDPDATHQARIEAAVSWRDSPGVEIDGGKGVGRVTKPGLPVAVGEAAINPVPRRM 60 VKD GDDPDATH A I + VSW SPGV IDGG+GVGRVTKPGLPV VGEAAINPVPR+M Sbjct: 66 VKDGGDDPDATHGALIVSTVSWASSPGVHIDGGEGVGRVTKPGLPVPVGEAAINPVPRQM 125 Query: 61 ILEAVSEVLEEHGAARGVRVVISVPEGEAIALKTLNPRXXXXXXXXXXXTRGVVTPFSTE 120 I EAV+EVL ++G RGV+VVISVP GE IA KTLNPR TRG+V PFST Sbjct: 126 IREAVNEVLAQYGLHRGVKVVISVPGGEEIAKKTLNPRLGIMGGISILGTRGIVVPFSTA 185 Query: 121 AYKXXXXXXXXXXXXMGNKQIILTTGGSSEKYAMAMFAELPEEAFIQMGEYVGFSLEHAK 180 AY+ G + +++TTGG SEKYAM + LPEEAFI+MG++VGF+L+ K Sbjct: 186 AYRASIVQALQVAKANGCRHVVITTGGRSEKYAMQEYPHLPEEAFIEMGDFVGFTLKQCK 245 Query: 181 AFGVRKITLVGMAGKFSKVAQGAMLIHSKNAPVDFSFLAKIAAESGADNELVGEIAAANT 240 G++ +++VGM GKFSKVAQG M++HSK+APVDF FLA +A ++GA + LV + ANT Sbjct: 246 RLGIKMVSMVGMMGKFSKVAQGVMMVHSKSAPVDFGFLAALAEQAGASSALVAAVRGANT 305 Query: 241 ASQVTDLMTAAGNGVFFEQLCLHACRHCLKHMNGGMTVEMVLVTMKGRVLGRA 293 A+QV D+M AG FFE LC CR L + GG+TV + TM G+ LG+A Sbjct: 306 AAQVGDMMQEAGCTKFFELLCEACCRAALNEVGGGLTVATSIYTMNGQRLGKA 358 >C3J3E1.1 C3J3E1_9BACI Cobalamin biosynthesis protein CbiD Length = 372 Score = 340 bits (871), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 169/293 (57%), Positives = 207/293 (70%) Query: 1 VKDAGDDPDATHQARIEAAVSWRDSPGVEIDGGKGVGRVTKPGLPVAVGEAAINPVPRRM 60 VKD GDDPDATH A I + VSW SPGV IDGG+GVGRVTKPGLPV VGEAAINPVPR+M Sbjct: 66 VKDGGDDPDATHGALIVSTVSWASSPGVHIDGGEGVGRVTKPGLPVPVGEAAINPVPRQM 125 Query: 61 ILEAVSEVLEEHGAARGVRVVISVPEGEAIALKTLNPRXXXXXXXXXXXTRGVVTPFSTE 120 I EAV+EVL ++G RGV+VVISVP GE IA KTLNPR TRG+V PFST Sbjct: 126 IREAVNEVLAQYGLHRGVKVVISVPGGEEIAKKTLNPRLGIIGGISILGTRGIVVPFSTA 185 Query: 121 AYKXXXXXXXXXXXXMGNKQIILTTGGSSEKYAMAMFAELPEEAFIQMGEYVGFSLEHAK 180 AY+ G + +++TTGG SEKYAM + LPEEAFI+MG++VGF+L+ K Sbjct: 186 AYRASIVQALQVAKANGCRHVVITTGGRSEKYAMQEYPHLPEEAFIEMGDFVGFTLKQCK 245 Query: 181 AFGVRKITLVGMAGKFSKVAQGAMLIHSKNAPVDFSFLAKIAAESGADNELVGEIAAANT 240 G++ +++VGM GKFSKVAQG M++HSK+APVDF FLA IA ++GA ELV + ANT Sbjct: 246 RLGIKMVSMVGMMGKFSKVAQGVMMVHSKSAPVDFGFLAAIAEQAGACPELVAAVRGANT 305 Query: 241 ASQVTDLMTAAGNGVFFEQLCLHACRHCLKHMNGGMTVEMVLVTMKGRVLGRA 293 A+QV D+M AG FFE LC C+ L + GG+TV + TM G+ LG+A Sbjct: 306 AAQVGDMMQEAGCTKFFELLCEACCQAALHEVGGGLTVATSIYTMNGQRLGKA 358 >B7Y6K0.1 B7Y6K0_9BACI Cobalamin biosynthesis protein CbiD Length = 372 Score = 340 bits (871), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 169/293 (57%), Positives = 207/293 (70%) Query: 1 VKDAGDDPDATHQARIEAAVSWRDSPGVEIDGGKGVGRVTKPGLPVAVGEAAINPVPRRM 60 VKD GDDPDATH A I + VSW SPGV IDGG+GVGRVTKPGLPV VGEAAINPVPR+M Sbjct: 66 VKDGGDDPDATHGALIVSTVSWASSPGVHIDGGEGVGRVTKPGLPVPVGEAAINPVPRQM 125 Query: 61 ILEAVSEVLEEHGAARGVRVVISVPEGEAIALKTLNPRXXXXXXXXXXXTRGVVTPFSTE 120 I EAV+EVL ++G RGV+VVISVP GE IA KTLNPR TRG+V PFST Sbjct: 126 IREAVNEVLAQYGLHRGVKVVISVPGGEEIAKKTLNPRLGIIGGISILGTRGIVVPFSTA 185 Query: 121 AYKXXXXXXXXXXXXMGNKQIILTTGGSSEKYAMAMFAELPEEAFIQMGEYVGFSLEHAK 180 AY+ G + +++TTGG SEKYAM + LPEEAFI+MG++VGF+L+ K Sbjct: 186 AYRASIVQALQVAKANGCRHVVITTGGRSEKYAMQEYPHLPEEAFIEMGDFVGFTLKQCK 245 Query: 181 AFGVRKITLVGMAGKFSKVAQGAMLIHSKNAPVDFSFLAKIAAESGADNELVGEIAAANT 240 G++ +++VGM GKFSKVAQG M++HSK+APVDF FLA IA ++GA ELV + ANT Sbjct: 246 RLGIKMVSMVGMMGKFSKVAQGVMMVHSKSAPVDFGFLAAIAEQAGACPELVAAVRGANT 305 Query: 241 ASQVTDLMTAAGNGVFFEQLCLHACRHCLKHMNGGMTVEMVLVTMKGRVLGRA 293 A+QV D+M AG FFE LC C+ L + GG+TV + TM G+ LG+A Sbjct: 306 AAQVGDMMQEAGCTKFFELLCEACCQAALHEVGGGLTVATSIYTMNGQRLGKA 358 >B4BMM7.1 B4BMM7_9BACI Cobalamin biosynthesis protein CbiD Length = 372 Score = 337 bits (864), Expect = 8e-91, Method: Compositional matrix adjust. Identities = 168/293 (57%), Positives = 206/293 (70%) Query: 1 VKDAGDDPDATHQARIEAAVSWRDSPGVEIDGGKGVGRVTKPGLPVAVGEAAINPVPRRM 60 VKD GDDPDATH A I + VSW SPGV IDGG+GVGRVTKPGLPV VGEAAINPVPR+M Sbjct: 66 VKDGGDDPDATHGALIVSTVSWASSPGVHIDGGEGVGRVTKPGLPVPVGEAAINPVPRQM 125 Query: 61 ILEAVSEVLEEHGAARGVRVVISVPEGEAIALKTLNPRXXXXXXXXXXXTRGVVTPFSTE 120 I EAV+EVL ++G GV+VVISVP GE IA KTLNPR TRG+V PFST Sbjct: 126 IREAVNEVLAQYGLHGGVKVVISVPGGEEIAKKTLNPRLGIIGGISILGTRGIVVPFSTA 185 Query: 121 AYKXXXXXXXXXXXXMGNKQIILTTGGSSEKYAMAMFAELPEEAFIQMGEYVGFSLEHAK 180 AY+ G + +++TTGG SEKYAM + LPEEAFI+MG++VGF+L+ K Sbjct: 186 AYRASIVQALQVAKANGCRHVVITTGGRSEKYAMQEYPHLPEEAFIEMGDFVGFTLKQCK 245 Query: 181 AFGVRKITLVGMAGKFSKVAQGAMLIHSKNAPVDFSFLAKIAAESGADNELVGEIAAANT 240 G++ +++VGM GKFSKVAQG M++HSK+APVDF FLA IA ++GA ELV + ANT Sbjct: 246 RLGIKMVSMVGMMGKFSKVAQGVMMVHSKSAPVDFGFLAAIAEQAGAGPELVAAVRGANT 305 Query: 241 ASQVTDLMTAAGNGVFFEQLCLHACRHCLKHMNGGMTVEMVLVTMKGRVLGRA 293 A+QV D+M AG FFE LC C+ L + GG+TV + TM G+ LG+A Sbjct: 306 AAQVGDMMQEAGCMKFFELLCEACCQAALHEVGGGLTVATSIYTMNGQQLGKA 358 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.379 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,566,045,858 Number of extensions: 59068380 Number of successful extensions: 165633 Number of sequences better than 1.0e-05: 423 Number of HSP's gapped: 164800 Number of HSP's successfully gapped: 423 Length of query: 297 Length of database: 3,060,696,203 Length adjustment: 135 Effective length of query: 162 Effective length of database: 1,788,859,178 Effective search space: 289795186836 Effective search space used: 289795186836 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 131 (55.1 bits)