BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0047.p (267 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1HRF0.1 B1HRF0_LYSSC Cobalt-precorrin-4 C(11)-methyltransferase... 363 1e-98 A3IB98.1 A3IB98_9BACI Precorrin-4 methylase 362 1e-98 C0Z7I6.1 C0Z7I6_BREBN Cobalt-precorrin-4 C(11)-methyltransferase 355 2e-96 O87696.1 CBIF_BACME Cobalt-precorrin-4 C(11)-methyltransferase E... 338 2e-91 C5DAP1.1 C5DAP1_9BACI Precorrin-4 C11-methyltransferase 332 2e-89 >B1HRF0.1 B1HRF0_LYSSC Cobalt-precorrin-4 C(11)-methyltransferase EC=2.1.1.- Length = 261 Score = 363 bits (931), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 166/255 (65%), Positives = 214/255 (83%) Query: 9 KVYIVGAGPGDPELITLKGSRILRSADVVLYADSLVSGELIASVKPGAEVLQSSGMALEQ 68 K+YIVGAGPGDP+LIT+KG +L++ADVV+Y DSLVS +LIA +P AE+++++GM LE+ Sbjct: 3 KIYIVGAGPGDPDLITVKGLHMLQTADVVMYTDSLVSEDLIAKARPDAEIIRTAGMHLEE 62 Query: 69 QVEIMTAAVKAGKSVARIHTGDPSMYGAILEQMSLLKLNGVSYEIVPGVSSVFASAAALG 128 V +M V AGK VAR+HTGDP+MYGAI+EQ++LLK G+ YE++PGVSSVFASAAA+G Sbjct: 63 MVAVMADRVHAGKIVARMHTGDPAMYGAIMEQVALLKKQGIGYEVIPGVSSVFASAAAIG 122 Query: 129 AELTVPELTQTVILTRAEGRTPVPEREQLRQLAAHHCTVALFLSASLAEHTASEFLAAGW 188 AELT+P+LTQT+ILTRAEGRTPVPE E+LR LA+HHCT+ALFLSA+L + E +AGW Sbjct: 123 AELTIPDLTQTLILTRAEGRTPVPEFEKLRDLASHHCTIALFLSATLTKKIVKELQSAGW 182 Query: 189 SPDTPIAVVKRATWPDQQILRTTVARLAADLREAGITMHAMILAGWALDPALTDRDQHRS 248 + DTP+AV++RA+WPDQ+I+RTT+ L +R GI HAMILAGWALDP + D+DQ+RS Sbjct: 183 ADDTPVAVIQRASWPDQKIVRTTLIELDEAMRVNGIRKHAMILAGWALDPNIHDKDQYRS 242 Query: 249 KLYDKTFTHGCREGI 263 KLYD TFTHG R+G+ Sbjct: 243 KLYDATFTHGFRKGV 257 >A3IB98.1 A3IB98_9BACI Precorrin-4 methylase Length = 261 Score = 362 bits (930), Expect = 1e-98, Method: Compositional matrix adjust. Identities = 166/255 (65%), Positives = 214/255 (83%) Query: 9 KVYIVGAGPGDPELITLKGSRILRSADVVLYADSLVSGELIASVKPGAEVLQSSGMALEQ 68 K+YIVGAGPGDP+LIT+KG +L++ADVV+Y DSLVS +LIA +P AE+++++GM LE+ Sbjct: 3 KIYIVGAGPGDPDLITVKGLHMLQTADVVMYTDSLVSEDLIAKARPDAEIIRTAGMHLEE 62 Query: 69 QVEIMTAAVKAGKSVARIHTGDPSMYGAILEQMSLLKLNGVSYEIVPGVSSVFASAAALG 128 V +M V AGK VAR+HTGDP+MYGAI+EQ++LLK G+ YE++PGVSSVFASAAA+G Sbjct: 63 MVAVMADRVHAGKIVARMHTGDPAMYGAIMEQVALLKKQGIGYEVIPGVSSVFASAAAIG 122 Query: 129 AELTVPELTQTVILTRAEGRTPVPEREQLRQLAAHHCTVALFLSASLAEHTASEFLAAGW 188 AELT+P+LTQT+ILTRAEGRTPVPE E+LR LA+HHCT+ALFLSA+L + E +AGW Sbjct: 123 AELTIPDLTQTLILTRAEGRTPVPEFEKLRDLASHHCTIALFLSATLTKKIVKELQSAGW 182 Query: 189 SPDTPIAVVKRATWPDQQILRTTVARLAADLREAGITMHAMILAGWALDPALTDRDQHRS 248 + DTP+AV++RA+WPDQ+I+RTT+ L +R GI HAMILAGWALDP + D+DQ+RS Sbjct: 183 ADDTPVAVIQRASWPDQKIVRTTLIELDEAMRVNGIRKHAMILAGWALDPDIHDKDQYRS 242 Query: 249 KLYDKTFTHGCREGI 263 KLYD TFTHG R+G+ Sbjct: 243 KLYDATFTHGFRKGV 257 >C0Z7I6.1 C0Z7I6_BREBN Cobalt-precorrin-4 C(11)-methyltransferase Length = 259 Score = 355 bits (912), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 168/256 (65%), Positives = 215/256 (83%), Gaps = 1/256 (0%) Query: 9 KVYIVGAGPGDPELITLKGSRILRSADVVLYADSLVSGELIASVKPGAEVLQSSGMALEQ 68 K+YIVGAGPGDP+LIT+KG ++L+ ADV++Y DSLV+ +L+A P AEVLQSSGMALE+ Sbjct: 2 KLYIVGAGPGDPDLITVKGLKLLQKADVIMYTDSLVNEDLVAMSNPNAEVLQSSGMALEE 61 Query: 69 QVEIMTAAVKAGKSVARIHTGDPSMYGAILEQMSLLKLNGVSYEIVPGVSSVFASAAALG 128 VE++ + +GK+V R+HTGDPS+YGAI+EQ++LLK G+ EIVPGVSSVFA+AAA+G Sbjct: 62 MVELLVDRIHSGKTVVRLHTGDPSIYGAIMEQIALLKEKGIEVEIVPGVSSVFAAAAAVG 121 Query: 129 AELTVPELTQTVILTRAEGRTPVPEREQLRQLAAHHCTVALFLSASLAEHTASEFLAAGW 188 AELT+P+LTQT+ILTRAEGRTPVPERE+LR LA HHCT+AL+LSA+L + E + AGW Sbjct: 122 AELTIPDLTQTIILTRAEGRTPVPEREKLRALAEHHCTLALYLSATLTKKVVRELVDAGW 181 Query: 189 SPDTPIAVVKRATWPDQQILRTTVARLAADLREAGITMHAMILAGWALDPALTDR-DQHR 247 S DTP+AVV+RA+WPDQ I+RTT+ L D+ + GI HAMILAGWALDP + D+ +Q+R Sbjct: 182 SEDTPVAVVQRASWPDQLIVRTTLKNLDEDMGKNGIRKHAMILAGWALDPNIHDKSEQYR 241 Query: 248 SKLYDKTFTHGCREGI 263 SKLYDKTFTHG R+G+ Sbjct: 242 SKLYDKTFTHGFRKGV 257 >O87696.1 CBIF_BACME Cobalt-precorrin-4 C(11)-methyltransferase EC=2.1.1.- Length = 258 Score = 338 bits (868), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 168/258 (65%), Positives = 207/258 (80%), Gaps = 1/258 (0%) Query: 9 KVYIVGAGPGDPELITLKGSRILRSADVVLYADSLVSGELIASVKPGAEVLQSSGMALEQ 68 K+YI+GAGPGDP+LIT+KG ++L+ ADVVLYADSLVS +LIA KPGAEVL+++GM LE+ Sbjct: 2 KLYIIGAGPGDPDLITVKGLKLLQQADVVLYADSLVSQDLIAKSKPGAEVLKTAGMHLEE 61 Query: 69 QVEIMTAAVKAGKSVARIHTGDPSMYGAILEQMSLLKLNGVSYEIVPGVSSVFASAAALG 128 V M ++ GK V R+HTGDP+MYGAI+EQM LLK GV EIVPGV+SVFA+AAA Sbjct: 62 MVGTMLDRMREGKMVVRVHTGDPAMYGAIMEQMVLLKREGVDIEIVPGVTSVFAAAAAAE 121 Query: 129 AELTVPELTQTVILTRAEGRTPVPEREQLRQLAAHHCTVALFLSASLAEHTASEFLAAGW 188 AELT+P+LTQTVILTRAEGRTPVPE E+L LA H CT+ALFLSA+L + EF+ AGW Sbjct: 122 AELTIPDLTQTVILTRAEGRTPVPEFEKLTDLAKHKCTIALFLSATLTKKVMKEFINAGW 181 Query: 189 SPDTPIAVVKRATWPDQQILRTTVARLAADLREAGITMHAMILAGWALDPALTDRDQHRS 248 S DTP+ VV +ATWPD++I+RTTV L +R GI AMILAGWALDP + D+D +RS Sbjct: 182 SEDTPVVVVYKATWPDEKIVRTTVKDLDDAMRTNGIRKQAMILAGWALDPHIHDKD-YRS 240 Query: 249 KLYDKTFTHGCREGIDAD 266 KLYDKTFTHG R+G+ ++ Sbjct: 241 KLYDKTFTHGFRKGVKSE 258 >C5DAP1.1 C5DAP1_9BACI Precorrin-4 C11-methyltransferase Length = 256 Score = 332 bits (851), Expect = 2e-89, Method: Compositional matrix adjust. Identities = 164/256 (64%), Positives = 200/256 (78%), Gaps = 2/256 (0%) Query: 9 KVYIVGAGPGDPELITLKGSRILRSADVVLYADSLVSGELIASV-KPGAEVLQSSGMALE 67 K+YI+GAGPG P+LIT+KG+++L+ AD + Y DSLV+GELI KP AEV ++GM LE Sbjct: 2 KLYIIGAGPGAPDLITVKGAQLLQEADAIFYTDSLVNGELIERYRKPEAEVFHTAGMHLE 61 Query: 68 QQVEIMTAAVKAGKSVARIHTGDPSMYGAILEQMSLLKLNGVSYEIVPGVSSVFASAAAL 127 Q VE M +K GK V RIHTGDPS+YGA LEQ++L K GV EIVPGVSSVFA+AAA+ Sbjct: 62 QMVEAMLEQLKQGKKVVRIHTGDPSVYGATLEQIALFKKQGVEVEIVPGVSSVFAAAAAV 121 Query: 128 GAELTVPELTQTVILTRAEGRTPVPEREQLRQLAAHHCTVALFLSASLAEHTASEFLAAG 187 AELTVP+LTQTVILTRAEGRTPVP RE+L LA H CT+ALFLSA+L + AG Sbjct: 122 QAELTVPDLTQTVILTRAEGRTPVPNREKLEDLAKHRCTLALFLSATLTKKVTKALRDAG 181 Query: 188 WSPDTPIAVVKRATWPDQQILRTTVARLAADLREAGITMHAMILAGWALDPALTDRDQHR 247 WS DTP+ +V +ATWPDQ+I+R+TV L D+R GI HA+ILAGWALDPA+ +RD +R Sbjct: 182 WSDDTPVVIVYKATWPDQKIVRSTVGTLDEDMRANGIRKHALILAGWALDPAIIERD-YR 240 Query: 248 SKLYDKTFTHGCREGI 263 SKLYDKTFTHG R+G+ Sbjct: 241 SKLYDKTFTHGYRQGV 256 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.131 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,452,860,280 Number of extensions: 53184703 Number of successful extensions: 184511 Number of sequences better than 1.0e-05: 2914 Number of HSP's gapped: 180164 Number of HSP's successfully gapped: 2923 Length of query: 267 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 134 Effective length of database: 1,807,701,208 Effective search space: 242231961872 Effective search space used: 242231961872 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 130 (54.7 bits)