BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0035.p (1395 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q2BFV3.1 Q2BFV3_9BACI 2',3'-cyclic nucleotide 2'-phosphodiestera... 1031 0.0 O34313.1 O34313_BACSU YfkN EC=3.1.3.5 EC=3.1.4.16 673 0.0 A7Z2G1.1 A7Z2G1_BACA2 YfkN EC=3.1.-.- 651 0.0 Q65MG5.1 Q65MG5_BACLD YfkN 648 0.0 A8FB01.1 A8FB01_BACP2 2',3'-cyclic-nucleotide 2'-phosphodiestera... 647 0.0 >Q2BFV3.1 Q2BFV3_9BACI 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic protein EC=3.1.3.6 Length = 1601 Score = 1031 bits (2666), Expect = 0.0, Method: Compositional matrix adjust. Identities = 577/1174 (49%), Positives = 751/1174 (63%), Gaps = 68/1174 (5%) Query: 1 MSTTDVHTNVYGWDYFKNAVSASVGLDRTSTLVKEARTEQPNNLLLDNGDLIQGTPLGTY 60 M TTD+HTN+ +DY+KNA S VGL RT+TL+++AR E+PN++L+DNGDLIQGTPLGTY Sbjct: 63 METTDIHTNLLNFDYYKNAASEKVGLARTATLIEDARKEEPNSVLVDNGDLIQGTPLGTY 122 Query: 61 MAKESGFEESADQIHPLIAAMNVMKYDAATFGNHEFNYGLNYLDRTINGSPADKSNTDAD 120 +AK E+ ++HP IAAMN M YD AT GNHEFNYGL++LD + DA+ Sbjct: 123 VAKIDPLEDG--ELHPSIAAMNTMGYDMATLGNHEFNYGLDFLDEAYD---------DAN 171 Query: 121 FPYVNANIY------NVSDGKNTFEPYVIIPKKVTDSQGNEVTIDVGLLGLVTPQIMDWD 174 F +VNAN+Y N + N F PY I+ K+VTD QGN TI +G +G PQI DWD Sbjct: 172 FDFVNANVYTDDQDDNPENDVNEFTPYRIVDKEVTDEQGNPQTIKIGYIGFAPPQINDWD 231 Query: 175 KVNLEGRVITKDIAETAAKFVPEMKAKGADVVIAMAHTGFDAAAVIGDGSENDINALSKV 234 K NL+G+V+TKDI E+A KF+P+MK +GADV+IAMAH+GF+ + +E+ + +LSKV Sbjct: 232 KANLDGKVVTKDIIESANKFIPQMKQEGADVIIAMAHSGFNGNE---ENTEDTVYSLSKV 288 Query: 235 PGIDAITFSHTHKVFPTNGDDTKLDASFKDPATKKPYDSAVAKIDNVNGHINDTPAVQAG 294 GIDAITFSHTHKVFP + LD FKD + K + +DN G IN AVQAG Sbjct: 289 EGIDAITFSHTHKVFPAKTE-AALDILFKDASGK-----VLPGVDNAKGTINGVAAVQAG 342 Query: 295 YGGGNLGLIDLKIVSDGSSWKVDKAASKASTRSIA-GVEVDPXXXXXXXXXXXXTIEYVN 353 YGGG+LGLIDL + G SW V S++STR ++ V +D TI+YVN Sbjct: 343 YGGGSLGLIDLTLEKQGDSWTV--TGSQSSTREVSTSVALDQEVVDAVTEAHNKTIDYVN 400 Query: 354 QPLGTTIAPMNSYFALVQDDPTVQIVTYAQQQYVSNLVNTDAALAKYKNLPILSVGAPFK 413 QP+GTT + SYFALVQDDP+VQ+VT AQ+ +V +N + +YK+LPILSVGAPFK Sbjct: 401 QPIGTTTDDIYSYFALVQDDPSVQVVTNAQKWFVEKYINLNKP--EYKDLPILSVGAPFK 458 Query: 414 AGRNGPEEYTEIKAGDLTIASASDLYLYDNTLKAIVVKGSTVKEWVEMSAGAFNRIKPAI 473 AGRNG EEYTEIK G+LTI SA DLYLYDNTLKA+ VKGS VKEW+EM+AG FN I PA Sbjct: 459 AGRNGAEEYTEIKKGNLTIRSAGDLYLYDNTLKAVKVKGSVVKEWIEMTAGKFNTIDPAK 518 Query: 474 STPQPLLNSAFAVYNFDVIDGIQYTIDVTKNAKYKPDGTVNDASSSRVTSITYGNEPLNP 533 + Q LLN +F VYNFDVIDG+ Y IDVTK AKY DG V +A+SSRV ++TY +P++P Sbjct: 519 TETQELLNPSFPVYNFDVIDGVNYQIDVTKPAKYDKDGKVVNANSSRVINLTYDGQPVDP 578 Query: 534 EQDFIVVTNNYRASGGGNFPDVKGAQMIIDSQMENRQVLMDYISAAGTVNPTADNNWSIA 593 +QDFIVVTNNYRA GGGNFP VKG+++++DS ENRQ+LMDYI+ T+ PTADNNWSIA Sbjct: 579 DQDFIVVTNNYRAGGGGNFPGVKGSELVVDSADENRQILMDYITEEETITPTADNNWSIA 638 Query: 594 PIQGNVNVTFTSSPKAAA-VKPD-NVTDTGNKDIKGFEIYNLNLKQNVPA--PTGDVEVH 649 PI +V VTFT+SPKA A +K D N++ TG K+ +GF I+N++LK PA P V+V Sbjct: 639 PIDADVKVTFTTSPKAEAYLKEDGNISYTGEKNDQGFGIFNIDLK-GTPAEQPNDHVKVQ 697 Query: 650 LLGINDFHGQLDTTSYVGSDAVGTAATLAAYLKNTRSQYANSLLFHNGDSVGASAPVSSL 709 LLG+ND HGQLDTT+ V A G AA +K + N+LL H GD +G S VS+L Sbjct: 698 LLGLNDLHGQLDTTTKVDGIASGRIDFTAAAMKEREADNQNTLLVHAGDMIGGSPLVSAL 757 Query: 710 ERDEPTMEWMNLMKFDVGSLGNHEFDQGVESMKTQIYGGKDPKTINNTSIVHKGADFDYI 769 +DEPT+E M M FDVG+LGNHEFD+G++ +K I GG+ P N + + G +F + Sbjct: 758 FQDEPTVEIMEAMGFDVGTLGNHEFDEGIDELKRMINGGQHP----NGTEDYDGMNFPVV 813 Query: 770 NANAIDSSTGVPIINPYXXXXXXXXXXXXXXXXXXATPSKVSPAGTAGVKFLSASEEVEA 829 AN D ST I PY TP + G +K ++EVEA Sbjct: 814 AANVYDDSTDELITEPYAVKEVGGQKIGFIGVVTQETPDMIVRKGNENLKI---TDEVEA 870 Query: 830 IEKYAAELQKKGVQTIVVLAHDPATTKGDSTTGEAADLAKALPADSPVDVVVAGDNHGFA 889 I KY ELQ++GV+ IVVLAH+P + + +A+ +A+ + D VD++ A NH Sbjct: 871 INKYTKELQEQGVEAIVVLAHNPTFQEQKADLYDASTIAENV--DDAVDIIFAAHNHVKV 928 Query: 890 NAIVNNKLIVQAYSYGTAFEDIKLVIDPITQDVKSKSATVTSTIQKNVTPDKETQDLVNY 949 N +V+NKLIVQAYSYGTAF D+ + IDP T D+ K+A + Q + TPD + ++ Sbjct: 929 NKVVDNKLIVQAYSYGTAFSDVDIEIDPATGDIVGKAAEIVQVKQSDYTPDADVAAILKK 988 Query: 950 YLNKHPELTKPVGTTDGTITRTDAY---NNE---SNLGNLIADAMRQADFGDGKGSADFA 1003 Y +K E K V + Y N+E + LGNLIAD M + ADFA Sbjct: 989 YADK-VEPIKAVVVGENATELAKGYPSVNSEYADNGLGNLIADGMIAS------MDADFA 1041 Query: 1004 FMNPGGIRADLPKGNVSFGDLAKVQPFGNTLVKLTLTGEQIKTLLQQQWGTKADGTADTK 1063 MN GG+RA+LP G V+FG L +QPFGN L K+ L+G ++T+L +Q K Sbjct: 1042 LMNGGGVRANLPAGEVTFGSLFAIQPFGNVLNKVKLSGADLETVLNKQITEKG------L 1095 Query: 1064 TLQISGLKYTANMYLPVAD-RIASLTKTDGTPISMTQSYTAVVNNFMAAGGDNYSVLTKA 1122 I+G KYT + ++ + DGTPI + YT V+NN+M G +Y + A Sbjct: 1096 DFHIAGFKYTYSWDSAAKKGKVVDILNEDGTPIDKNKEYTVVMNNYM-YGNLSYGIAELA 1154 Query: 1123 SESLAGPIDLDVFYDYVKKTFKGGPITAAIEGRI 1156 ++ G IDLD D+VK K P T +EGRI Sbjct: 1155 TDLEVGQIDLDATVDFVKTLEK--PFTYGVEGRI 1186 Score = 119 bits (297), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 67/183 (36%), Positives = 104/183 (56%), Gaps = 7/183 (3%) Query: 1213 ITFEDLGKVAWAQEAINALAAKGIIKGIDGKNFAPNKTVTRAEFVTMLVRALDLAPSG-A 1271 ++F+D+ K+ W +E I LA+K I++G + F PN + TR + +L R+L L+P Sbjct: 1415 VSFKDISKI-WNKEDIETLASKYIVQGYEDGTFKPNTSTTRLQLALLLTRSLGLSPEADY 1473 Query: 1272 STKFSDVKQGVWYTDAIAAAVNAGIVKGSGNGKFEPGREVTREEMALMIAAALKDQL--- 1328 +F D+ + Y + I AAV AGI+KG +GKF+P V RE+ A MI A+ D + Sbjct: 1474 DGRFKDIGKSSKYAEEIMAAVEAGIIKGKQDGKFDPNETVNREQAAAMIKRAM-DYMSYD 1532 Query: 1329 -QSIDTASALAGFGDKSKIASYAQEAVAQLTQLGIVNGVDGQKFAPKSDATRAQAAVIIY 1387 D + +L D+ KI+S+A+E + L Q G+++G KF PK + TRAQ +I Sbjct: 1533 ASKADKSKSLDSLKDQKKISSFAKEDIEFLLQAGVMSGKLDGKFDPKGNTTRAQIVKMIQ 1592 Query: 1388 RML 1390 L Sbjct: 1593 NAL 1595 >O34313.1 O34313_BACSU YfkN EC=3.1.3.5 EC=3.1.4.16 Length = 1462 Score = 673 bits (1736), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/1202 (37%), Positives = 637/1202 (52%), Gaps = 121/1202 (10%) Query: 1 MSTTDVHTNVYGWDYFKNAVSASVGLDRTSTLVKEARTEQPNNLLLDNGDLIQGTPLGTY 60 ++TTD+H N+ +DY+ + +A GL RT+ L+++ R + PN LL+DNGDLIQG PLG Y Sbjct: 48 LATTDIHANMMDYDYYSDKETADFGLARTAQLIQKHREQNPNTLLVDNGDLIQGNPLGEY 107 Query: 61 MAKESGFEE-SADQIHPLIAAMNVMKYDAATFGNHEFNYGLNYLDRTINGSPADKSNTDA 119 K + S + HP+I+ MN +KYDA T GNHEFNYGL++LD TI G A Sbjct: 108 AVKYQKDDIISGTKTHPIISVMNALKYDAGTLGNHEFNYGLDFLDGTIKG---------A 158 Query: 120 DFPYVNANIYNVSDGKNTFEPYVIIPKKVTDSQGNEVTIDVGLLGLVTPQIMDWDKVNLE 179 DFP VNAN+ S G+N + PYVI K + D GNE + VG +G V PQIM WDK NLE Sbjct: 159 DFPIVNANVKTTS-GENRYTPYVINEKTLIDENGNEQKVKVGYIGFVPPQIMTWDKKNLE 217 Query: 180 GRVITKDIAETAAKFVPEMKAKGADVVIAMAHTGFDAAAVIGDGSENDINAL-SKVPGID 238 G+V +DI E+A + +P+MKA+GADV+IA+AHTG + A G+EN + L +K GID Sbjct: 218 GQVQVQDIVESANETIPKMKAEGADVIIALAHTGIEKQAQ-SSGAENAVFDLATKTKGID 276 Query: 239 AITFSHTHKVFPTNGDDTKLDASFKDPATKKPYDSAVAKIDNVNGHINDTPAVQAGYGGG 298 AI H H +FP+ A + + VA+ + G IN P V G Sbjct: 277 AIISGHQHGLFPS--------AEY----------AGVAQFNVEKGTINGIPVVMPSSWGK 318 Query: 299 NLGLIDLKIVSDGSSWKVDKAASKASTRSIAG--VEVDPXXXXXXXXXXXXTIEYVNQPL 356 LG+IDLK+ SWKV A SK S SIAG + T+EYV +P+ Sbjct: 319 YLGVIDLKLEKADGSWKV--ADSKGSIESIAGNVTSRNETVTNTIQQTHQNTLEYVRKPV 376 Query: 357 GTTIAPMNSYFALVQDDPTVQIVTYAQQQYVSNLVNTDAALAKYKNLPILSVGAPFKAG- 415 G T A +NS+FA V+DDP++QIVT AQ+ Y + +YKNLPILS GAPFKAG Sbjct: 377 GKTEADINSFFAQVKDDPSIQIVTDAQKWYAEKEMKD----TEYKNLPILSAGAPFKAGG 432 Query: 416 RNGPEEYTEIKAGDLTIASASDLYLYDNTLKAIVVKGSTVKEWVEMSAGAFNRIKPAIST 475 RNG YT I AGDL I + DLYLYDNT++ + + GS VK+W+EMSAG FN+I PA Sbjct: 433 RNGANYYTNIPAGDLAIKNVGDLYLYDNTVQIVKLTGSEVKDWLEMSAGQFNQIDPAKGG 492 Query: 476 PQPLLNSAFAVYNFDVIDGIQYTIDVTKNAKYKPDGTVNDASSSRVTSITYGNEPLNPEQ 535 Q LLN F YNFDVIDG+ Y +DVTK AKY +G V +A SSR+ +++Y +P++P Q Sbjct: 493 DQALLNENFRSYNFDVIDGVTYQVDVTKPAKYNENGKVINADSSRIINLSYEGKPISPSQ 552 Query: 536 DFIVVTNNYRASGGGNFPDVKGAQMIIDSQMENRQVLMDYISAAGTVNPTADNNWSIAPI 595 +F+VVTNNYRASGGG FP + +++ S +ENRQVLMDYI TVNP ADNNWSIAP+ Sbjct: 553 EFLVVTNNYRASGGGGFPHLTSDKIVHGSAVENRQVLMDYIIEQKTVNPKADNNWSIAPV 612 Query: 596 QGNVNVTFTSS--PKAAAVKPDNVTDTGNKDIKGFEIYNLNLKQNV---PAPTGDVEVHL 650 G N+TF SS K A K D+V G +G+ +Y L + P G ++ + Sbjct: 613 SG-TNLTFESSLLAKPFADKADDVAYVGKSANEGYGVYKLQFDDDSNPDPPKDGLWDLTV 671 Query: 651 LGINDFHGQLDTTSYVGSDAVGTAATLAAYLKNTRSQYANSLLFHNGDSVGASAPVSSLE 710 + ND H LD AA + RS+ +++L GD + Sbjct: 672 MHTNDTHAHLD-----------DAARRMTKINEVRSETNHNILLDAGDVFSGDLYFTKW- 719 Query: 711 RDEPTMEWMNLMKFDVGSLGNHEFDQGVESMKTQIYGGKDPKTINNTSIVH-KGADFDYI 769 ++ MN+M +D + GNHEFD+G + + G + T++ + H + +F + Sbjct: 720 NGLADLKMMNMMGYDAMTFGNHEFDKGPTVLSDFLSG--NSATVDPANRYHFEAPEFPIV 777 Query: 770 NANAIDSSTGVPI-------------------INPYXXXXXXXXXXXXXXXXXXATPSKV 810 +AN +D S + I+PY T + Sbjct: 778 SAN-VDVSNEPKLKSFVKKPQTFTAGEKKEAGIHPYILLDVDGEKVAVFGLTTEDTATTS 836 Query: 811 SPAGTAGVK--FLSASEEVEAIEKYAAELQKKGVQTIVVLAHDPATTKGDSTTGEAADLA 868 SP + F +A V+AI+ +++ V I+ L H G DL Sbjct: 837 SPGKSIVFNDAFETAQNTVKAIQ------EEEKVNKIIALTH----------IGHNRDLE 880 Query: 869 KALPADSPVDVVVAGDNHGFAN--AIVNNK---LIVQAYSYGTAFEDIKLVIDPITQDVK 923 A +D+++ G H + +VNN+ ++ QA YG + + D Sbjct: 881 LAKKVKG-IDLIIGGHTHTLVDKMEVVNNEEPTIVAQAKEYGQFLGRVDVAFDEKGVVQT 939 Query: 924 SKSATVTSTIQKNVTPDKETQDLVNYYLNKHPEL-TKPVGTTDGTI--TRTDAYNNESNL 980 KS I ++ + E + ++ + N+ ++ + VG TD + R E+NL Sbjct: 940 DKSNLSVLPIDEHTEENPEAKQELDQFKNELEDVKNEKVGYTDVALDGQREHVRTKETNL 999 Query: 981 GNLIADAMRQADFGDGKGSADFAFMNPGGIRADLPKGNVSFGDLAKVQPFGNTLVKLTLT 1040 GN IAD M A + G A A N GGIRA + KG+++ G++ V PFGNTL LT Sbjct: 1000 GNFIADGML-AKAKEAAG-ARIAITNGGGIRAGIDKGDITLGEVLNVMPFGNTLYVADLT 1057 Query: 1041 GEQIKTLLQQQWGTKADGTADTKTLQISGLKYTANMYLPVADRIASLT----KTDGTPIS 1096 G+QIK L+Q +G Q++G++YT + R+ + D I+ Sbjct: 1058 GKQIKEALEQGLSNVENGGGAFP--QVAGIEYTFTLNNKPGHRVLEVKIESPNGDKVAIN 1115 Query: 1097 MTQSYTAVVNNFMAAGGDNYSVLTKAS--ESLAGPIDLDVFYDYVKKTFKGGPITAAIEG 1154 +Y NNF+ AGGD YSV T+AS E L G +D ++F + +KK G ++ +EG Sbjct: 1116 TDDTYRVATNNFVGAGGDGYSVFTEASHGEDL-GYVDYEIFTEQLKKL--GNKVSPKVEG 1172 Query: 1155 RI 1156 RI Sbjct: 1173 RI 1174 >A7Z2G1.1 A7Z2G1_BACA2 YfkN EC=3.1.-.- Length = 1430 Score = 651 bits (1680), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/1205 (37%), Positives = 626/1205 (51%), Gaps = 128/1205 (10%) Query: 1 MSTTDVHTNVYGWDYFKNAVSASVGLDRTSTLVKEARTEQPNNLLLDNGDLIQGTPLGTY 60 ++TTDVH N+ +DY+ + + GL RT+ L+++ R E PN LL+DNGDLIQG PLG Y Sbjct: 48 LATTDVHANMMDYDYYSDKPTTEFGLARTAQLIEKHRRENPNTLLVDNGDLIQGNPLGEY 107 Query: 61 MAK-ESGFEESADQIHPLIAAMNVMKYDAATFGNHEFNYGLNYLDRTINGSPADKSNTDA 119 K E S + HP+I MN + YDA T GNHEFNYGL +LD TI G A Sbjct: 108 AVKYEKNDIISGAKTHPIIEVMNSLHYDAGTLGNHEFNYGLEFLDGTIKG---------A 158 Query: 120 DFPYVNANIYNVSDGKNTFEPYVIIPKKVTDSQGNEVTIDVGLLGLVTPQIMDWDKVNLE 179 D+P VNAN+ +S G+N + PYVI K VTD G + I VG +G V PQIM WDK NLE Sbjct: 159 DYPIVNANVKTLS-GENRYTPYVIKDKTVTDENGGKHQIKVGYIGFVPPQIMTWDKKNLE 217 Query: 180 GRVITKDIAETAAKFVPEMKAKGADVVIAMAHTGFDAAAVIGDGSENDINAL-SKVPGID 238 GRV +DI E+A K VP+MKA+GAD+VIA+AH+G + A G+EN + L +KV GID Sbjct: 218 GRVQVEDIVESAKKTVPKMKAEGADIVIALAHSGIEKKAQ-SSGAENAVFDLATKVSGID 276 Query: 239 AITFSHTHKVFPTNGDDTKLDASFKDPATKKPYDSAVAKIDNVNGHINDTPAVQAGYGGG 298 AI H H +FP DA +K + D G IN P V + G Sbjct: 277 AIVSGHQHGLFP--------DAEYK----------GADQFDVDKGTINGIPVVMSSSWGK 318 Query: 299 NLGLIDLKIVSDGSSWKVDKAASKASTRSIAG--VEVDPXXXXXXXXXXXXTIEYVNQPL 356 G+IDL++ S+W V+ A K S IAG + T++Y+ +P+ Sbjct: 319 YAGVIDLRLEKTDSAWHVEDA--KGSIEPIAGNVTSENETVVNTVKKAHEGTLKYIREPV 376 Query: 357 GTTIAPMNSYFALVQDDPTVQIVTYAQQQYVSNLVNTDAALAKYKNLPILSVGAPFKAG- 415 G T A +NS+FA V+DDP++QIVT AQ+ Y N + +YK+LPILS GAPFKAG Sbjct: 377 GQTKADINSFFAQVKDDPSIQIVTDAQKWYAENKMKD----TEYKDLPILSAGAPFKAGG 432 Query: 416 RNGPEEYTEIKAGDLTIASASDLYLYDNTLKAIVVKGSTVKEWVEMSAGAFNRIKPAIST 475 RNG YT I AGDL I + DLYLYDNT++ + + GS VK+W+EMSAG FN+I A Sbjct: 433 RNGSNYYTNISAGDLAIKNIGDLYLYDNTVQIVKLNGSEVKDWLEMSAGQFNQIDQAKGG 492 Query: 476 PQPLLNSAFAVYNFDVIDGIQYTIDVTKNAKYKPDGTVNDASSSRVTSITYGNEPLNPEQ 535 Q LLN A+ YNFDVIDG+ Y +DVTK AKY +GTV +SR+ +++Y +P++ +Q Sbjct: 493 SQALLNDAYRSYNFDVIDGVTYQVDVTKPAKYNENGTVIHPDASRIVNLSYQGKPVSAKQ 552 Query: 536 DFIVVTNNYRASGGGNFPDVKGAQMIIDSQMENRQVLMDYISAAGTVNPTADNNWSIAPI 595 +F++VTNNYRASGGG FP + +++ S ENRQVLMDYI T+NP AD+NWSI P+ Sbjct: 553 EFLIVTNNYRASGGGGFPHLSNDKIVYSSADENRQVLMDYIIQQKTINPQADHNWSILPV 612 Query: 596 QGNVNVTFTSS--PKAAAVKPDNVTDTGNKDIKGFEIYNLNLKQNVPA---PTGDV-EVH 649 +G N+TF SS K A + D+V G G+ Y L K + P P D ++ Sbjct: 613 KG-TNLTFESSLAAKPFADRADDVAYIGESQNAGYGQYKLQFKDDEPGTDPPKDDAWKLT 671 Query: 650 LLGINDFHGQLDTTSYVGSDAVGTAATLAAYLKNTRSQYANSLLFHNGDSVGASAPVSSL 709 ++ ND H LD AA +K RS+ S+L GD + Sbjct: 672 VMHTNDTHAHLD-----------NAARRMTKIKEIRSETDRSILLDAGDVFSGDLYFTKW 720 Query: 710 ERDEPTMEWMNLMKFDVGSLGNHEFDQGVESMKTQIYG---GKDPKTINNTSIVHKGADF 766 + ++ MN M +D + GNHEFD+G ++ + + G DP N + DF Sbjct: 721 Q-GLADLKLMNSMGYDAMTFGNHEFDKGPGALASFLSGNGSAADPSGKYN----FQAPDF 775 Query: 767 DYINANAIDSSTGVPI-------------------INPYXXXXXXXXXXXXXXXXXXATP 807 +++N +D S + I PY T Sbjct: 776 PLVSSN-VDVSKESKLRPFMKKADTFTAGKKKKAGIYPYILLDVNGEKVAVFGLTTEDTS 834 Query: 808 SKVSPAGTAGVK--FLSASEEVEAIEKYAAELQKKGVQTIVVLAHDPATTKGDSTTGEAA 865 SP + F SA + V+ I+ K+ V I+ L H G Sbjct: 835 VTSSPGKSIVFHDAFQSAQDTVKEIQ------NKEHVNKIIALTH----------IGHQR 878 Query: 866 DLAKALPADSPVDVVVAGDNHGFANA--IVNNK---LIVQAYSYGTAFEDIKLVIDPITQ 920 DL A +D++V G H + +V N+ ++ QA YG + D Sbjct: 879 DLDLAKKVKG-IDLIVGGHTHTLVDKMEVVKNEEPTIVAQAKEYGEYLGRADVAFDKNGV 937 Query: 921 DVKSKSATVTSTIQKNVTPDKETQDLVNYYLNKHPEL-TKPVGTTDGTI--TRTDAYNNE 977 + +S+ + + D + + ++ + + + + VG+T + R + E Sbjct: 938 VLPEQSSLQAIPVNEQTKEDPDLKKELDPFKKELVSVKNEKVGSTKVALDGQREHVRSKE 997 Query: 978 SNLGNLIADAMRQADFGDGKGSADFAFMNPGGIRADLPKGNVSFGDLAKVQPFGNTLVKL 1037 +NLGN IAD M Q A A N GGIRA + KG ++ GD+ V PFGNTL Sbjct: 998 TNLGNFIADGMLQK--AKEAAGAQIAITNGGGIRAGIDKGEITLGDVLNVMPFGNTLYVA 1055 Query: 1038 TLTGEQIKTLLQQQW-GTKADGTADTKTLQISGLKYTANMYLPVADRI--ASLTKTDGT- 1093 LTG+QIK L+Q G +A G A Q++GL YT + R+ A+ + DG+ Sbjct: 1056 DLTGKQIKQALEQGLSGIEAQGGA---FPQVAGLTYTFTLNKKPGHRVLQAAAVQDDGSV 1112 Query: 1094 -PISMTQSYTAVVNNFMAAGGDNYSVLTKAS--ESLAGPIDLDVFYDYVKKTFKGGPITA 1150 PIS ++Y +NF+ GGD YSV +AS E L G +D +VF + ++K G + Sbjct: 1113 KPISDKKTYRVATSNFVGEGGDGYSVFNEASHKEDL-GFVDYEVFTEQLEKA--GKAVEP 1169 Query: 1151 AIEGR 1155 ++GR Sbjct: 1170 KVDGR 1174 >Q65MG5.1 Q65MG5_BACLD YfkN Length = 1445 Score = 648 bits (1671), Expect = 0.0, Method: Compositional matrix adjust. Identities = 442/1203 (36%), Positives = 623/1203 (51%), Gaps = 124/1203 (10%) Query: 1 MSTTDVHTNVYGWDYFKNAVSASVGLDRTSTLVKEARTEQPNNLLLDNGDLIQGTPLGTY 60 + TTD+H ++ +DY+ + +A GL RT+ L+++ R+ PN +L+DNGDLIQG PLG Y Sbjct: 50 LGTTDIHAHMMDYDYYADKETAEFGLARTAQLIEKYRSRNPNTILVDNGDLIQGNPLGEY 109 Query: 61 MAK-ESGFEESADQIHPLIAAMNVMKYDAATFGNHEFNYGLNYLDRTINGSPADKSNTDA 119 + K E S + HP+I MN ++YDA T GNHEFNYGL +LD TI G A Sbjct: 110 IFKHERESIISGTKTHPIIDVMNKLQYDAGTLGNHEFNYGLEFLDGTIKG---------A 160 Query: 120 DFPYVNANIYNVSDGKNTFEPYVIIPKKVTDSQGNEVTIDVGLLGLVTPQIMDWDKVNLE 179 +FP VNANI DGKN + PY I + +TD G + + VG +G V PQI+ WDK +L+ Sbjct: 161 EFPIVNANI-KTPDGKNKYTPYHIEDRTLTDESGRKHQLKVGYIGFVPPQILTWDKKHLD 219 Query: 180 GRVITKDIAETAAKFVPEMKAKGADVVIAMAHTGFDAAAVIGDGSENDINALS-KVPGID 238 G++ +DI E+A + +P+MK +GADV+IA+AH+G + G+EN + L+ K GID Sbjct: 220 GKITVQDITESAKETIPKMKQEGADVIIAIAHSGIENGEQAA-GAENAVYDLALKTEGID 278 Query: 239 AITFSHTHKVFPTNGDDTKLDASFKDPATKKPYDSAVAKIDNVNGHINDTPAVQAGYGGG 298 AI H H +FP T P + IDN G IN P V G Sbjct: 279 AIISGHQHGLFP---------------GTDYPGNGV---IDNQKGTINGIPVVMPKNWGS 320 Query: 299 NLGLIDLKIVSDGSSWKVDKAASKASTRSIAG--VEVDPXXXXXXXXXXXXTIEYVNQPL 356 +LG+ID+++ DG WKV A++K T +IAG + T+EYV P+ Sbjct: 321 HLGIIDMQLELDGGKWKVKDASAK--TEAIAGNVTSRNETVVSAIKDTHEKTLEYVRAPV 378 Query: 357 GTTIAPMNSYFALVQDDPTVQIVTYAQQQYVSNLVNTDAALAKYKNLPILSVGAPFKAG- 415 G T A +NS+FA V+DDP++QIVT AQ+ Y +++ +Y+NLPILS GAPFKAG Sbjct: 379 GQTEADINSFFAQVKDDPSIQIVTDAQKWYAEDVMKG----TEYENLPILSAGAPFKAGG 434 Query: 416 RNGPEEYTEIKAGDLTIASASDLYLYDNTLKAIVVKGSTVKEWVEMSAGAFNRIKPAIST 475 RNG + YT IKAG+L I + DLYLYDNTL + + GS VK+W+EMSAG FN+I P+ S Sbjct: 435 RNGADYYTNIKAGNLAIKNIGDLYLYDNTLYIVKLTGSEVKDWIEMSAGQFNQIDPSKSG 494 Query: 476 PQPLLNSAFAVYNFDVIDGIQYTIDVTKNAKYKPDGTVNDASSSRVTSITYGNEPLNPEQ 535 Q LLN F YNFDVIDG+ Y IDVT+ AKY G V + ++RV ++Y +P+ +Q Sbjct: 495 EQALLNPDFRSYNFDVIDGVTYQIDVTQPAKYNASGGVKNPQANRVKQLSYNGKPVRDDQ 554 Query: 536 DFIVVTNNYRASGGGNFPDVKGAQMIIDSQMENRQVLMDYISAAGTVNPTADNNWSIAPI 595 +F+VVTNNYRASGGG FP + +++ + ENRQVLM+YI TVNP ADNNWSIAPI Sbjct: 555 EFLVVTNNYRASGGGGFPHLTQDKVVYAAADENRQVLMNYIMEKKTVNPAADNNWSIAPI 614 Query: 596 QGNVNVTFTSS--PKAAAVKPDNVTDTGNKDIKGFEIYNLNLKQNVPAPTGDVEVHL--L 651 +G +VTF SS K A K +++ + KG+ +Y LN + P P D L + Sbjct: 615 KG-ADVTFESSLLAKPFAEKANDIDFVRESENKGYGVYKLNFDGSEP-PVDDENWTLTVM 672 Query: 652 GINDFHGQLDTTSYVGSDAVGTAATLAAYLKNTRSQYANSLLFHNGDSVGASAPVSSLER 711 ND H LD AA AA +K RS+ N++L GD + Sbjct: 673 HTNDTHAHLD-----------GAARRAAKVKEIRSETENNVLLDAGDVFSGDLYFTKW-N 720 Query: 712 DEPTMEWMNLMKFDVGSLGNHEFDQGVESMKTQI---YGGKDPKTINNTSIVHKGADFDY 768 ++ MN+M +D + GNHEFD+G + + + Y DP +N + + DF Sbjct: 721 GLADLKLMNMMGYDAMTFGNHEFDKGPKVLADFLSGNYTAVDP--LNRHQL--EKPDFPI 776 Query: 769 INANAIDSSTGVPI-------------------INPYXXXXXXXXXXXXXXXXXXATPSK 809 +++N +D S + I PY T Sbjct: 777 VSSN-VDVSKEPKLRSFQKEPAVLAAGKKKESGIYPYILLDVNGEQVGVFGLTTEDTSYT 835 Query: 810 VSPAGTAGVKFLSASEEVEAIEKYAAELQKKGVQTIVVLAHDPATTKGDSTTGEAADLAK 869 SP + F A + E K E +K V I+ L H G DL Sbjct: 836 SSPG--PNIAFHDAYQSAEKTVKELKEKEK--VNKIIALTH----------LGYNRDLEL 881 Query: 870 ALPADSPVDVVVAGDNHGFAN--AIVNNK---LIVQAYSYGTAFEDIKLVIDP--ITQDV 922 A +D+++ G H + +V N+ ++ Q YG + +V D + Q Sbjct: 882 AKKVKG-IDLIIGGHTHTLVDHLKVVENEEPTIVAQVKDYGQFLGRVDVVFDENGVVQTD 940 Query: 923 KSKSATVTSTIQKNVTPDKETQDLVNYYLNKHPEL-TKPVGTTDGTI--TRTDAYNNESN 979 +S+ + I V D +++++ + EL K VG D + R + E+N Sbjct: 941 QSRFNLI--AIDDKVDEDPPGKEVLDGFKEDIDELKKKKVGYADVPLDGKREHVRSKETN 998 Query: 980 LGNLIADAMRQADFGDGKGSADFAFMNPGGIRADLPKGNVSFGDLAKVQPFGNTLVKLTL 1039 LGN IAD M + G AD A N GGIR+ + KG ++ GD+ V PFGNTL L Sbjct: 999 LGNFIADGMLKK--AKQAGGADIAITNGGGIRSGIAKGEITLGDVLTVMPFGNTLYAADL 1056 Query: 1040 TGEQIKTLLQQQWGTKADGTADTKTLQISGLKYTANMYLPVADRIASLT----KTDGTPI 1095 TG QIK L+ +G +SGL +T + P +RI + K D P+ Sbjct: 1057 TGAQIKEALEHGVSQVEEGGGAFP--HVSGLSFTFTLSKPKGERILDVNLVNDKGDAVPL 1114 Query: 1096 SMTQSYTAVVNNFMAAGGDNYSVLTKASESL-AGPIDLDVFYDYVKKTFKGGPITAAIEG 1154 + ++Y NNFM GGD YSV +A + G D D+F + + ++ IE Sbjct: 1115 DLDKTYRVATNNFMGGGGDGYSVFKEAKNGVDLGFTDYDIFTEQLALY---DSVSPNIEN 1171 Query: 1155 RIT 1157 RIT Sbjct: 1172 RIT 1174 >A8FB01.1 A8FB01_BACP2 2',3'-cyclic-nucleotide 2'-phosphodiesterase EC=3.1.4.16 Length = 1408 Score = 647 bits (1670), Expect = 0.0, Method: Compositional matrix adjust. Identities = 441/1204 (36%), Positives = 627/1204 (52%), Gaps = 126/1204 (10%) Query: 1 MSTTDVHTNVYGWDYFKNAVSASVGLDRTSTLVKEARTEQPNNLLLDNGDLIQGTPLGTY 60 ++TTDVH N+ +DY+ + + GL +T+ L+ + R++ PN LL+DNGDLIQGTPLG Y Sbjct: 27 LATTDVHANMMNYDYYSDKETNEFGLAKTAELIDKHRSQNPNTLLVDNGDLIQGTPLGEY 86 Query: 61 MAK-ESGFEESADQIHPLIAAMNVMKYDAATFGNHEFNYGLNYLDRTINGSPADKSNTDA 119 + K E + ++HP+I +N +KYDA T GNHEFNYGL++LD TI G A Sbjct: 87 VYKQEKDSIINQTKVHPIIHTLNKLKYDAGTLGNHEFNYGLSFLDGTIAG---------A 137 Query: 120 DFPYVNANIYNVSDGKNTFEPYVIIPKKVTDSQGNEVTIDVGLLGLVTPQIMDWDKVNLE 179 +FP VNAN+ + +G++ F PYVI K D+ G T+ VG +G V PQIM WDK +L+ Sbjct: 138 NFPIVNANVKKL-NGEHRFTPYVIQDKTFKDANGTSQTVKVGYIGFVPPQIMTWDKKHLD 196 Query: 180 GRVITKDIAETAAKFVPEMKAKGADVVIAMAHTGFDAAAVIGDGSENDINAL-SKVPGID 238 G+V +DI E+A + +PEMK KGADV++A+AHTG + A GSEN I L +K GID Sbjct: 197 GQVQVQDIVESANETIPEMKEKGADVIVALAHTGIEKTAS-PKGSENMIFDLATKTKGID 255 Query: 239 AITFSHTHKVFPTNGDDTKLDASFKDPATKKPYDSAVAKIDNVNGHINDTPAVQAGYGGG 298 AI H H FP+ A + + V K + G IN P V + G Sbjct: 256 AIVSGHQHGTFPS--------AEY----------NGVDKFNVSKGTINGIPVVMSKNWGS 297 Query: 299 NLGLIDLKIVSDGSSWKVDKAASKASTRSIAGVEV-DPXXXXXXXXXXXXTIEYVNQPLG 357 LG+IDL + DGS+WKV K S+AGV + T++YV +P+G Sbjct: 298 YLGVIDLTLEPDGSNWKVTDGTGK--IESVAGVSSQNSTVKDAIQTTHQNTLDYVRKPVG 355 Query: 358 TTIAPMNSYFALVQDDPTVQIVTYAQQQYVSNLVNTDAALAKYKNLPILSVGAPFKAG-R 416 T A +NS+FA V DDP++QIVT AQ+ Y + + Y+NLPILS GAPFKAG R Sbjct: 356 KTEADINSFFAQVMDDPSIQIVTDAQKWYAQEKMKDTS----YQNLPILSAGAPFKAGGR 411 Query: 417 NGPEEYTEIKAGDLTIASASDLYLYDNTLKAIVVKGSTVKEWVEMSAGAFNRIKPAISTP 476 NG YT I GDL I + DLYLYDNT++ + +KGS VK+W+EMSAG FN+IKP + Sbjct: 412 NGVNYYTNIAKGDLAIKNIGDLYLYDNTVQIVKLKGSEVKDWLEMSAGQFNQIKPNDAKE 471 Query: 477 QPLLNSAFAVYNFDVIDGIQYTIDVTKNAKYKPDGTVNDASSSRVTSITYGNEPLNPEQD 536 QP+LN + YNFDVIDG+ Y +DVT+ AKY GT+ +A+++R+ +++Y +P++ Q+ Sbjct: 472 QPILNEEYRSYNFDVIDGVTYQVDVTQPAKYSTTGTLVNANANRIKNLSYNGKPVSDNQE 531 Query: 537 FIVVTNNYRASGGGNFPDVKGAQMIIDSQMENRQVLMDYISAAGTVNPTADNNWSIAPIQ 596 F+VVTNNYRASGGG FP + ++++ S ENRQVLMDYI T+NP+AD NWSIAPI+ Sbjct: 532 FLVVTNNYRASGGGGFPHLTQDKVVLASADENRQVLMDYIIEQKTINPSADQNWSIAPIK 591 Query: 597 GNVNVTFTSS--PKAAAVKPDNVTDTGNKDIKGFEIYNLNLKQN---VPAPTGDVEVHLL 651 G VTF SS K A K NV N G +Y L K + P + + + ++ Sbjct: 592 G-ATVTFESSLLAKPFAEKSSNVDFIRNASTDGLGVYKLAFKDDGTTEPPASDNWNLTVM 650 Query: 652 GINDFHGQLDTTSYVGSDAVGTAATLAAYLKNTRSQYANSLLFHNGDSVGASAPVSSLER 711 ND H LD AA A +K R++ N++L GD + + Sbjct: 651 HTNDTHAHLD-----------DAARRATKIKEVRAENKNNILLDAGDVFSGDLYFTKWQ- 698 Query: 712 DEPTMEWMNLMKFDVGSLGNHEFDQGVESMKTQIYGGK---DPKTINNTSIVHKGADFDY 768 ++ MNLMK+D + GNHEFD+G ++ + G DPK + + F Sbjct: 699 GLADLKLMNLMKYDAMTFGNHEFDKGPSVLRQFLTGDASDVDPKNRHQ----FEKPRFPV 754 Query: 769 INANAIDSSTGVPI-------------------INPYXXXXXXXXXXXXXXXXXXATPSK 809 +++N +D S + I PY T Sbjct: 755 VSSN-VDVSKEKQLSDLVKKPASFKAGEKKEAGIYPYILLDVNGEKVAVFGLTTEDTAIT 813 Query: 810 VSPAGTAGVK--FLSASEEVEAIEKYAAELQKKGVQTIVVLAHDPATTKGDSTTGEAADL 867 S K + A E V I+ ++ + I+ L H G DL Sbjct: 814 SSSGPNIQFKDAYKKAKETVNTIQ------TEEKINKIIALTH----------IGYNRDL 857 Query: 868 AKALPADSPVDVVVAGDNHGFAN--AIVNNK---LIVQAYSYGTAFEDIKLVIDPITQDV 922 A D +D+++ G H ++N K ++ Q YG + + D Sbjct: 858 ELAQKVDG-IDLIIGGHTHTLVEKLKVINKKEPTIVAQVKDYGQFLGKVDVAFDKKGVVQ 916 Query: 923 KSKSATVTSTIQKNVTPDKETQDLVNYYLNKHPEL-TKPVGTTDGTI--TRTDAYNNESN 979 +S+ I +V D E + +++ Y +L T+ VG TD + R E+N Sbjct: 917 PKESSFDLIPIDDSVKEDAEAKAILDGYKADIQDLKTEKVGHTDVLLDGQREHVRAKETN 976 Query: 980 LGNLIADAMRQADFGDGKGSADFAFMNPGGIRADLPKGNVSFGDLAKVQPFGNTLVKLTL 1039 LGN IAD M Q AD A N GGIR + KG+++ GD+ V PFGNTL L Sbjct: 977 LGNFIADGMLQK--AQESAGADLAITNGGGIRGSIEKGDITLGDILTVMPFGNTLYVADL 1034 Query: 1040 TGEQIKTLLQQQW-GTKADGTADTKTLQISGLKYTANMYLPVADRIASLTKTDG----TP 1094 G QIK L+Q G + G A ++G++YT + P R+ ++ D T Sbjct: 1035 KGSQIKKALEQGLSGIEEGGGA---FPHVAGIEYTFTLSKPAGSRLINVKLKDQKGQLTD 1091 Query: 1095 ISMTQSYTAVVNNFMAAGGDNYSVLTKAS--ESLAGPIDLDVFYDYVKKTFKGGPITAAI 1152 I ++Y N F+ GGD YSV T+AS E L G +D ++F + ++K G I+ I Sbjct: 1092 IDDEKTYRVATNAFVGTGGDGYSVFTEASHGEDL-GYVDYEIFKEQIEKA--DGQISPVI 1148 Query: 1153 EGRI 1156 + R+ Sbjct: 1149 DHRV 1152 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.312 0.130 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 7,933,648,450 Number of extensions: 343454209 Number of successful extensions: 699608 Number of sequences better than 1.0e-05: 3874 Number of HSP's gapped: 682482 Number of HSP's successfully gapped: 6147 Length of query: 1395 Length of database: 3,060,696,203 Length adjustment: 149 Effective length of query: 1246 Effective length of database: 1,656,964,968 Effective search space: 2064578350128 Effective search space used: 2064578350128 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.9 bits) S2: 138 (57.8 bits)