BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0541.0023.p (229 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KB71.1 B3KB71_9BACI Response regulator receiver 324 4e-87 B1DDI1.1 B1DDI1_9BACL Two component transcriptional regulator, w... 285 2e-75 A5D566.1 A5D566_PELTS Response regulator 235 3e-60 Q67SE3.1 Q67SE3_SYMTH Two-component response regulator 230 6e-59 C1TA75.1 C1TA75_9FIRM Two component transcriptional regulator, w... 213 1e-53 >B3KB71.1 B3KB71_9BACI Response regulator receiver Length = 228 Score = 324 bits (830), Expect = 4e-87, Method: Compositional matrix adjust. Identities = 163/229 (71%), Positives = 182/229 (79%), Gaps = 2/229 (0%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 MR ILI+DDDEKIISMLRRGLAFEGYDV TA+NGA+GL+ +L+ Sbjct: 1 MRSRILIVDDDEKIISMLRRGLAFEGYDVLTASNGAEGLKVILSEDPDVVVLDVMMPQVD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 GFE RRLREGGST+PVLMLTAKDE+E+RVKGLD GADDYLVKPF Sbjct: 61 GFEALRRLREGGSTIPVLMLTAKDEVENRVKGLDTGADDYLVKPFALEELLARVRALLRR 120 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 K+ G +S+ +++ED+ +D D+REV RGG+RLELTAKEFELLHLFMQNPKRVLSRDLI Sbjct: 121 KT--GDDTSNHRLTFEDLVMDTDAREVIRGGQRLELTAKEFELLHLFMQNPKRVLSRDLI 178 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILRGD 229 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILRGD Sbjct: 179 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILRGD 227 >B1DDI1.1 B1DDI1_9BACL Two component transcriptional regulator, winged helix family Length = 230 Score = 285 bits (729), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 138/229 (60%), Positives = 172/229 (75%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 MR +I+++DDDEKI S+LRR LAFEGY+V TA+NG +GLR +L + Sbjct: 1 MRQHIMVVDDDEKITSLLRRSLAFEGYEVSTASNGMEGLRLLLTADPDMLILDVMMPQVD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G+EVCRR+REGGSTVP+LMLTAKD+I RVKGLD GADDYL+KPF Sbjct: 61 GWEVCRRVREGGSTVPILMLTAKDDISDRVKGLDAGADDYLIKPFALEELLARVRALLRR 120 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 KS++ SS + ++D+ LD+DSRE R G+R+ELTAKE++LL LFMQNP+RVL+RD I Sbjct: 121 KSDKIDESSSNKIVFDDLALDLDSREAIRSGRRIELTAKEYDLLLLFMQNPRRVLTRDAI 180 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILRGD 229 M+KIWGYD+SGESNVLEVYIAMLRQK EE G KR+IQT+RG GY+LRG+ Sbjct: 181 MEKIWGYDFSGESNVLEVYIAMLRQKLEEGGAKRIIQTVRGTGYVLRGE 229 >A5D566.1 A5D566_PELTS Response regulator Length = 225 Score = 235 bits (599), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 120/227 (52%), Positives = 155/227 (68%), Gaps = 3/227 (1%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 M IL+IDDD KI +MLRR L FEG++V+TA G +GLR Sbjct: 1 MEAKILVIDDDRKITAMLRRCLVFEGFEVQTAAGGEEGLRLAAAWKPDLVVLDVLMPGTD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G+EVCRRLR GS++P+LMLTAKDE+ RVKGLDLGADDYLVKPF Sbjct: 61 GWEVCRRLR-AGSSLPILMLTAKDEVADRVKGLDLGADDYLVKPFALEELLARIRALL-- 117 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 + + ++ + + Y D+TLD +REV RGG+ ++LTA+EFELL LFM++P++VL+RD I Sbjct: 118 RRSRQADTAMRPLVYADLTLDHATREVRRGGRPIQLTAREFELLALFMEHPRQVLTRDQI 177 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 MD++WG DY GESNVLEVY+ MLRQK EE G KR+I T+RG GY+L+ Sbjct: 178 MDRVWGIDYGGESNVLEVYVGMLRQKLEEGGEKRIIHTVRGVGYVLK 224 >Q67SE3.1 Q67SE3_SYMTH Two-component response regulator Length = 228 Score = 230 bits (587), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 112/227 (49%), Positives = 144/227 (63%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 M +L++DDD KI + LRR L EGYDV A +G + LR+V S Sbjct: 1 MSLRVLVVDDDPKITAFLRRSLTLEGYDVAVANSGTEALRSVTASPPDLMVLDIMMPDVD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G EVCRR+R G T P+LMLTA+D + RVKGLD GADDYLVKPF Sbjct: 61 GLEVCRRIRAAGETFPILMLTARDAVSDRVKGLDQGADDYLVKPFALEELLARLRALSRR 120 Query: 121 KSEQGGGSSDQAVSYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDLI 180 + G + + Y D+ LD +RE RG +++ LTAKE+ELLHLF+ +P++VL+RD + Sbjct: 121 GAPAQGEDGHRVLQYADLRLDTATREAYRGDRQISLTAKEYELLHLFLSHPRQVLTRDTL 180 Query: 181 MDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 M+K+WGYDYSGESNVLEVY+A LR K E G RLIQT+RG GY+L+ Sbjct: 181 MEKVWGYDYSGESNVLEVYVAYLRNKLEAGGEPRLIQTVRGVGYVLK 227 >C1TA75.1 C1TA75_9FIRM Two component transcriptional regulator, winged helix family Length = 225 Score = 213 bits (541), Expect = 1e-53, Method: Compositional matrix adjust. Identities = 112/228 (49%), Positives = 149/228 (65%), Gaps = 5/228 (2%) Query: 1 MRPNILIIDDDEKIISMLRRGLAFEGYDVKTATNGADGLRAVLNSXXXXXXXXXXXXXXX 60 M NIL+IDDD +I ++L+R L F GY V+ A +G G+ + N+ Sbjct: 1 MSSNILVIDDDPRITALLKRTLLFNGYTVEAANDGKAGITLLENNHFDLVILDVMMPGLD 60 Query: 61 GFEVCRRLREGGSTVPVLMLTAKDEIEHRVKGLDLGADDYLVKPFXXXXXXXXXXXXXXX 120 G++VC ++RE +PVLMLTA+DE+E RVKGLDLGADDYLVKPF Sbjct: 61 GWQVCGQIREY-YDLPVLMLTARDEVEDRVKGLDLGADDYLVKPFAMTELLARIRALL-- 117 Query: 121 KSEQGGGSSDQAV-SYEDITLDVDSREVTRGGKRLELTAKEFELLHLFMQNPKRVLSRDL 179 G + A+ SY D+++D +REV R ++L TA+E+ELL LFM+NP+ VL+++L Sbjct: 118 -RRSGKTEAQPAILSYADLSMDTGTREVFRNKRQLNPTAREYELLKLFMENPRLVLNKEL 176 Query: 180 IMDKIWGYDYSGESNVLEVYIAMLRQKTEEHGGKRLIQTIRGAGYILR 227 IM++IWGYDY GESNVLEVYI MLR K E G KRLI T+RGAGY+L+ Sbjct: 177 IMERIWGYDYQGESNVLEVYIVMLRNKLEACGEKRLIHTVRGAGYVLK 224 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.139 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,178,755,437 Number of extensions: 41026380 Number of successful extensions: 178394 Number of sequences better than 1.0e-05: 18813 Number of HSP's gapped: 152113 Number of HSP's successfully gapped: 18961 Length of query: 229 Length of database: 3,060,696,203 Length adjustment: 131 Effective length of query: 98 Effective length of database: 1,826,543,238 Effective search space: 179001237324 Effective search space used: 179001237324 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)