BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0538.0009.p (612 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q8F6S0.1 Q8F6S0_LEPIN Heat shock protein htpG 543 e-152 Q72PK2.1 Q72PK2_LEPIC HtpG 543 e-152 Q1DCH3.1 Q1DCH3_MYXXD ATPase, histidine kinase-, DNA gyrase B-, ... 527 e-147 Q08Y08.1 Q08Y08_STIAU HtpG 506 e-141 A4A1B8.1 A4A1B8_9PLAN HtpG 476 e-132 >Q8F6S0.1 Q8F6S0_LEPIN Heat shock protein htpG Length = 603 Score = 543 bits (1400), Expect = e-152, Method: Compositional matrix adjust. Identities = 274/597 (45%), Positives = 405/597 (67%), Gaps = 11/597 (1%) Query: 8 TYRFQVNLSGMINILSNHLYSSPKVFLRELLQNGIDAITARQAYSPDGYEGKIHVEVSGT 67 +++FQVNL G+IN+LS HLYS P+VF+RELLQNG+DAI AR P+ EG+IH+E+ Sbjct: 2 SHKFQVNLRGIINLLSEHLYSGPQVFVRELLQNGVDAIQARSYLEPEN-EGEIHLEIIPG 60 Query: 68 STGA--TLLVEDNGIGLNEAEIHEFLAMIGQSSKRGEDFLSTNTSFIGRFGIGLLSCFMV 125 G TL+ DNG+GL E+EIHEFLA IGQSSKRGE + FIG+FG+GLLSCF+V Sbjct: 61 KDGTPPTLIFTDNGVGLVESEIHEFLATIGQSSKRGE--FQSPKGFIGQFGVGLLSCFIV 118 Query: 126 SDDIVMVTQSAKGG--PALEWRGKPDGTYTIRKLEGQHAPGTKVFLRCKEGSEAYFEENN 183 SD++V+VT+S K PA EWRGK DGTY+I+ L GT+V+L CK GSE YFE Sbjct: 119 SDEVVVVTRSVKDKTQPAFEWRGKQDGTYSIKTLGSDLPFGTQVYLLCKPGSEEYFERET 178 Query: 184 LQEGLFHYGALLPYPIQLVSDRNTRLINPLTPPWVKDPQLARKHRDEVLAFGKQVLGETF 243 L + +G LL P+Q + +T L+NP PW + + + R L FGK++ +F Sbjct: 179 LCNLVKKFGGLLSVPLQFLEGESTELLNPEPAPWNRTYRSKAQERKTFLDFGKKLFETSF 238 Query: 244 RDFIPLHTASGRTGGIAFILPQAVNLNAKRNHRVYLKHMLVSEAASNILPDWAFFVKCLI 303 D IPL + G+ GIAF+LP + +L K HR+YLK+ML+SE+A+++LPDWAFFVKC++ Sbjct: 239 FDAIPLTSDIGKVQGIAFVLPYSPSLAQKNIHRIYLKNMLLSESAASLLPDWAFFVKCVV 298 Query: 304 WTDELQPTASREHFYENAQLEQVREELGNSIRQELMRMAEYDPDRLQSIISLHALSMKAL 363 +DEL+PTASRE FYE+ LE+ RE LG +R L+ ++E +P+RL+ +I+LH LSMKAL Sbjct: 299 NSDELRPTASREDFYEDQSLEKARETLGQCLRDYLIALSEDEPERLRHLINLHHLSMKAL 358 Query: 364 AVEDLSFYSIIHEWLPFESTFGRKPLGELKQ-HPPLYFTATLDEYRQITHVASAQSMLVV 422 AV+D F+ +I ++LPFE+TFGR L E ++ +P + + ++ D+YRQI+ VA+AQ ++ Sbjct: 359 AVQDSDFFRLIIDFLPFETTFGRMTLKEFREKNPVIRYVSSHDQYRQISGVAAAQGEAII 418 Query: 423 NGGFIYDAELLSRLPLVDPDVETERLLPEEVSLSFTDITPQERLDYYESVRLADSVLQKF 482 NGG++YD+ELL R + P E++ + +F DIT +ER ++ +++AD VL+ F Sbjct: 419 NGGYVYDSELLERFSELYP---VEQVDAAGFAQTFEDITLEERDSVFDFLQVADQVLRPF 475 Query: 483 RCQVQLRRFKPEEIPVLYTLSEESAQWRVLEATKEVSTDALSSVLGSLGATLKDAAYATL 542 +C +++F P E+P+LY LS+E R +E +KE++ S +L +L + A L Sbjct: 476 QCVTDIKKFLPIEMPMLYHLSQEGDFLRSVEHSKEIANKMWSDILNNLSDSYSKEINAYL 535 Query: 543 YFNLNNPVIERAFHPAHQKMLPSIIEMLYCNALMMGHYPMNRQEIALLNKGIIQFID 599 +FNL NP+I++ +++ ++MLY AL+MGH+P++ +E++LL G+ I+ Sbjct: 536 FFNLRNPLIQKLVKLKDVQLIGRAVQMLYIQALLMGHHPLHVKELSLLTGGLSDLIE 592 >Q72PK2.1 Q72PK2_LEPIC HtpG Length = 603 Score = 543 bits (1400), Expect = e-152, Method: Compositional matrix adjust. Identities = 274/597 (45%), Positives = 405/597 (67%), Gaps = 11/597 (1%) Query: 8 TYRFQVNLSGMINILSNHLYSSPKVFLRELLQNGIDAITARQAYSPDGYEGKIHVEVSGT 67 +++FQVNL G+IN+LS HLYS P+VF+RELLQNG+DAI AR P+ EG+IH+E+ Sbjct: 2 SHKFQVNLRGIINLLSEHLYSGPQVFVRELLQNGVDAIQARSYLEPEN-EGEIHLEIIPG 60 Query: 68 STGA--TLLVEDNGIGLNEAEIHEFLAMIGQSSKRGEDFLSTNTSFIGRFGIGLLSCFMV 125 G TL+ DNG+GL E+EIHEFLA IGQSSKRGE + FIG+FG+GLLSCF+V Sbjct: 61 KDGTPPTLIFTDNGVGLVESEIHEFLATIGQSSKRGE--FQSPKGFIGQFGVGLLSCFIV 118 Query: 126 SDDIVMVTQSAKGG--PALEWRGKPDGTYTIRKLEGQHAPGTKVFLRCKEGSEAYFEENN 183 SD++V+VT+S K PA EWRGK DGTY+I+ L GT+V+L CK GSE YFE Sbjct: 119 SDEVVVVTRSVKDKTQPAFEWRGKQDGTYSIKTLGSDLPFGTQVYLLCKPGSEEYFERET 178 Query: 184 LQEGLFHYGALLPYPIQLVSDRNTRLINPLTPPWVKDPQLARKHRDEVLAFGKQVLGETF 243 L + +G LL P+Q + +T L+NP PW + + + R L FGK++ +F Sbjct: 179 LCNLVKKFGGLLSVPLQFLEGESTELLNPEPAPWNRTYRSKAQERKTFLDFGKKLFETSF 238 Query: 244 RDFIPLHTASGRTGGIAFILPQAVNLNAKRNHRVYLKHMLVSEAASNILPDWAFFVKCLI 303 D IPL + G+ GIAF+LP + +L K HR+YLK+ML+SE+A+++LPDWAFFVKC++ Sbjct: 239 FDAIPLTSDIGKVQGIAFVLPYSPSLAQKNIHRIYLKNMLLSESAASLLPDWAFFVKCVV 298 Query: 304 WTDELQPTASREHFYENAQLEQVREELGNSIRQELMRMAEYDPDRLQSIISLHALSMKAL 363 +DEL+PTASRE FYE+ LE+ RE LG +R L+ ++E +P+RL+ +I+LH LSMKAL Sbjct: 299 NSDELRPTASREDFYEDQSLEKARETLGQCLRDYLIALSEDEPERLRHLINLHHLSMKAL 358 Query: 364 AVEDLSFYSIIHEWLPFESTFGRKPLGELKQ-HPPLYFTATLDEYRQITHVASAQSMLVV 422 AV+D F+ +I ++LPFE+TFGR L E ++ +P + + ++ D+YRQI+ VA+AQ ++ Sbjct: 359 AVQDSDFFRLIIDFLPFETTFGRMTLKEFREKNPVIRYVSSHDQYRQISGVAAAQGEAII 418 Query: 423 NGGFIYDAELLSRLPLVDPDVETERLLPEEVSLSFTDITPQERLDYYESVRLADSVLQKF 482 NGG++YD+ELL R + P E++ + +F DIT +ER ++ +++AD VL+ F Sbjct: 419 NGGYVYDSELLERFSELYP---VEQVDAAGFAQTFEDITLEERDSVFDFLQVADQVLRPF 475 Query: 483 RCQVQLRRFKPEEIPVLYTLSEESAQWRVLEATKEVSTDALSSVLGSLGATLKDAAYATL 542 +C +++F P E+P+LY LS+E R +E +KE++ S +L +L + A L Sbjct: 476 QCVTDIKKFLPIEMPMLYHLSQEGDFLRSVEHSKEIANKMWSDILNNLSDSYSKEINAYL 535 Query: 543 YFNLNNPVIERAFHPAHQKMLPSIIEMLYCNALMMGHYPMNRQEIALLNKGIIQFID 599 +FNL NP+I++ +++ ++MLY AL+MGH+P++ +E++LL G+ I+ Sbjct: 536 FFNLRNPLIQKLVKLKDVQLIGRAVQMLYIQALLMGHHPLHVKELSLLTGGLSDLIE 592 >Q1DCH3.1 Q1DCH3_MYXXD ATPase, histidine kinase-, DNA gyrase B-, and HSP90-like domain protein Length = 618 Score = 527 bits (1358), Expect = e-147, Method: Compositional matrix adjust. Identities = 271/595 (45%), Positives = 387/595 (65%), Gaps = 8/595 (1%) Query: 9 YRFQVNLSGMINILSNHLYSSPKVFLRELLQNGIDAITARQAYSPDGYEGKIHVEVSGTS 68 +RFQV+L G+I++LS+HLYSSP V++RELLQN DAI ARQ P G+ G + +E+ Sbjct: 3 HRFQVSLRGVIDLLSHHLYSSPGVYVRELLQNATDAIRARQLLEP-GHAGTVRLELMEKQ 61 Query: 69 TGA--TLLVEDNGIGLNEAEIHEFLAMIGQSSKRGEDFLSTNTSFIGRFGIGLLSCFMVS 126 G+ TLL D+G+GL E EIH FLA IG+SSKR E + FIG+FGIGLLSCFMV Sbjct: 62 DGSPPTLLFTDDGVGLTEDEIHRFLATIGESSKR-EALEARRNDFIGQFGIGLLSCFMVC 120 Query: 127 DDIVMVTQSAKG-GPALEWRGKPDGTYTIRKLEGQHA-PGTKVFLRCKEGSEAYFEENNL 184 D++++VT+SA+G G LEWRG+ DGTY +R E A PGT+VFL + +F L Sbjct: 121 DELLVVTRSARGDGRTLEWRGRHDGTYAVRPSEHPLAQPGTQVFLVARPDMAHWFTATRL 180 Query: 185 QEGLFHYGALLPYPIQLVSDRNTRLINPLTPPWVKDPQLARKHRDEVLAFGKQVLGETFR 244 + HYG LLP+PI L +D+ T ++ PW ++ A + R +LA+G+++ F Sbjct: 181 RNLASHYGGLLPFPIHLTTDQGTERLDTSGAPWRREYDSASERRKALLAYGRELFDTDFV 240 Query: 245 DFIPLHTASGRTGGIAFILPQAVNLNAKRNHRVYLKHMLVSEAASNILPDWAFFVKCLIW 304 D IPL + +G G+A++LP + + N+++ HRVYLKHML+SE+A N+LP+WAFFVKC++ Sbjct: 241 DCIPLRSTAGDVDGVAYVLPASPHFNSRQKHRVYLKHMLLSESAENLLPEWAFFVKCVVN 300 Query: 305 TDELQPTASREHFYENAQLEQVREELGNSIRQELMRMAEYDPDRLQSIISLHALSMKALA 364 + L+PTASRE FYE+ L RE LG S+R LM +A DP LQ +I+LH LS+KALA Sbjct: 301 ANALRPTASRESFYEDDALAAARESLGQSLRGYLMELAREDPRALQRLIALHGLSVKALA 360 Query: 365 VEDLSFYSIIHEWLPFESTFGRKPLGELKQ-HPPLYFTATLDEYRQITHVASAQSMLVVN 423 ++D FY +I WLPFE++ G L + ++ HP + +T+TLD +RQI VA AQ + ++N Sbjct: 361 LDDDDFYRLIIHWLPFETSMGMMTLADYRRAHPVVRYTSTLDGFRQIAQVAGAQGLCIIN 420 Query: 424 GGFIYDAELLSRLPLVDPDVETERLLPEEVSLSFTDITPQERLDYYESVRLADSVLQKFR 483 + +D LL +LP PDV+ E ++ SF ++T ER + +R+A++VL FR Sbjct: 421 AAYTHDTSLLEKLPHAVPDVQVEPFSSADLPQSFDELTLDEREATFPLLRMAENVLAPFR 480 Query: 484 CQVQLRRFKPEEIPVLYTLSEESAQWRVLEATKEVSTDALSSVLGSLGATLKDAAYATLY 543 C +++F P E+P LY+ E A R E +E S D + VL S+ A + A L Sbjct: 481 CGAVVKKFYPAEVPTLYSSDAEGAFRRDAERAREESDDLYAGVLDSVMAA-SGSEPAQLC 539 Query: 544 FNLNNPVIERAFHPAHQKMLPSIIEMLYCNALMMGHYPMNRQEIALLNKGIIQFI 598 FNL+NPV+ R A + ML +EMLY AL++GH+P+N QE+ LLN+G++ I Sbjct: 540 FNLHNPVVRRLAAVADRDMLKLSVEMLYVQALLLGHHPLNAQEMVLLNQGLLGLI 594 >Q08Y08.1 Q08Y08_STIAU HtpG Length = 656 Score = 506 bits (1302), Expect = e-141, Method: Compositional matrix adjust. Identities = 273/610 (44%), Positives = 392/610 (64%), Gaps = 14/610 (2%) Query: 9 YRFQVNLSGMINILSNHLYSSPKVFLRELLQNGIDAITARQAYSPDGYEGKIHVEVSGTS 68 +RFQ+NL G+I++LS+HLYSSP V++RELLQN DAI ARQ P G+EG I +E+ Sbjct: 47 HRFQINLRGVIDLLSHHLYSSPDVYIRELLQNATDAIRARQHLEP-GHEGSIRIELIEKQ 105 Query: 69 TGA--TLLVEDNGIGLNEAEIHEFLAMIGQSSKRGEDFLSTNTSFIGRFGIGLLSCFMVS 126 G TLL D+GIGL E EIH FLA IG+SSKR E FIG+FGIGLLSCFMV Sbjct: 106 DGGPPTLLFSDDGIGLTEEEIHRFLATIGESSKR-EVLAERRGDFIGQFGIGLLSCFMVC 164 Query: 127 DDIVMVTQSAKGG-PALEWRGKPDGTYTIRKLEGQ--HAPGTKVFLRCKEGSEAYFEENN 183 D++++VT+SA+GG P +EWRG+ DG YT+R G PGT+VFL + + + F Sbjct: 165 DEVLVVTRSAQGGSPTMEWRGRHDGIYTVRP-SGHPLERPGTQVFLVARPDAASLFTPQR 223 Query: 184 LQEGLFHYGALLPYPIQLVSDRNTRLINPLTPPWVKDPQLARKHRDEVLAFGKQVLGETF 243 ++E HYG LLP+PI L + + IN PW + A + R +LA+G+ V G TF Sbjct: 224 VRELALHYGGLLPFPIHLTAGGYSGRINTEGAPWRRTYGSASERRAALLAYGRDVFGMTF 283 Query: 244 RDFIPLHTASGRTGGIAFILPQAVNLNAKRNHRVYLKHMLVSEAASNILPDWAFFVKCLI 303 D IPL + +G G+AF+LP + + NAK+ HRVYLK+ML+SE+A N+LP+WAFFVKC++ Sbjct: 284 IDCIPLKSEAGDVEGVAFVLPFSPHYNAKQKHRVYLKNMLLSESAENLLPEWAFFVKCVV 343 Query: 304 WTDELQPTASREHFYENAQLEQVREELGNSIRQELMRMAEYDPDRLQSIISLHALSMKAL 363 ++L+PTASRE FYEN L + R LG ++R+ L+ +A+ DP LQ +I LHALSMKAL Sbjct: 344 NANDLRPTASRESFYENDTLTRARTALGQALRRYLVELAKDDPRALQGLIQLHALSMKAL 403 Query: 364 AVEDLSFYSIIHEWLPFESTFGRKPLGELKQ-HPPLYFTATLDEYRQITHVASAQSMLVV 422 A++D FY +I WLPFE++ G L + +Q + + ++LDE+RQ++ VA+AQ + V+ Sbjct: 404 ALDDDDFYRLIIGWLPFETSLGAMTLADYRQTSSQVRYVSSLDEFRQVSRVAAAQGLCVL 463 Query: 423 NGGFIYDAELLSRLPLVDPDVETERLLPEEVSLSFTDITPQERLDYYESVRLADSVLQKF 482 N ++YD +LL +LP V D + ER ++ SF ++T ER + + A+ VLQ F Sbjct: 464 NAAYVYDTDLLEKLPRVFQDAQVERFSASDLPQSFDELTLDEREAVFPLRKRAEEVLQPF 523 Query: 483 RCQVQLRRFKPEEIPVLYTLSEESAQWRVLEATKEVSTDALSSVLGSLGATLKDAAYATL 542 C V +++F+P+E+P LY+ +A R E +E S D +S+L + + L Sbjct: 524 GCGVVVKKFRPKEVPTLYSSDTGNAFRRDAERAREESDDLYASMLEGVVSGASGNEQPLL 583 Query: 543 YFNLNNPVIERAFHPAHQKMLPSIIEMLYCNALMMGHYPMNRQEIALLNKGIIQFIDWGL 602 FN +NPV+ R ++ +EMLY AL++GH P+N +E+ LLN+G++ I Sbjct: 584 TFNFHNPVVRRLAAVTDPHLIKLSVEMLYVQALLLGHRPLNAREMLLLNQGLLGLI---- 639 Query: 603 TASHVTGGDE 612 AS + GG+E Sbjct: 640 -ASRLEGGEE 648 >A4A1B8.1 A4A1B8_9PLAN HtpG Length = 595 Score = 476 bits (1225), Expect = e-132, Method: Compositional matrix adjust. Identities = 251/599 (41%), Positives = 385/599 (64%), Gaps = 19/599 (3%) Query: 13 VNLSGMINILSNHLYSSPKVFLRELLQNGIDAITARQAYSPDGYEGKIHVEV-SGTSTGA 71 + L G+I +LS HLYS P VF+RELLQNG+DAI AR+ P +EG I +EV + + Sbjct: 1 MELRGLIELLSQHLYSGPHVFIRELLQNGVDAIQARRQIEPK-HEGAIEIEVVTSEESDP 59 Query: 72 TLLVEDNGIGLNEAEIHEFLAMIGQSSKRGEDFLSTNTSFIGRFGIGLLSCFMVSDDIVM 131 T++ +DNG+GL EAE+ +FLA IGQSSKRGE S F+G+FGIGLLSCF VSD+I++ Sbjct: 60 TIIFQDNGVGLTEAEVQQFLATIGQSSKRGEA-TSRPDDFLGQFGIGLLSCFTVSDEIIV 118 Query: 132 VTQSAKG--GPALEWRGKPDGTYTIRKLEGQHAPGTKVFLRCKEGSEAYFEENNLQEGLF 189 +T+SAKG P EWRG DGTY++RKL GT+VFL+ G E YFE + + Sbjct: 119 LTRSAKGENQPGFEWRGSTDGTYSVRKLTEMIPIGTQVFLQPSTGYEDYFELQRILKLTR 178 Query: 190 HYGALLPYPIQLVSDRNTRLINPLTPPWVKD---PQLARKHRDEVLAFGKQVLGETFRDF 246 YG+LL I L S+ T +IN +P W +D PQ+ R+ +LA+G +V F D Sbjct: 179 DYGSLLQPKISLTSNGKTDVINAKSP-WQQDLTNPQV----RENLLAYGTEVFDRNFLDV 233 Query: 247 IPLHTASGRTGGIAFILPQAVNLNAKRNHRVYLKHMLVSEAASNILPDWAFFVKCLIWTD 306 PLH+ SG G+A++L +AV+ + + HRVYLK+ML+S + ++LP+WAFFV+C++ Sbjct: 234 FPLHSTSGGVTGVAYVLSEAVHAGSSQPHRVYLKNMLLSTKSHDVLPEWAFFVQCIVNAT 293 Query: 307 ELQPTASREHFYENAQLEQVREELGNSIRQELMRMAEYDPDRLQSIISLHALSMKALAVE 366 +L PTASRE FY++ LE+ R+ELG+ +R+ L+ MA+ P R + +I++H L++KALA + Sbjct: 294 QLHPTASRESFYDDTVLERTRDELGDCLRRYLVEMAQTQPRRFEQLIAVHHLAVKALAAD 353 Query: 367 DLSFYSIIHEWLPFESTFGRKPLGEL-KQHPPLYFTATLDEYRQITHVASAQSMLVVNGG 425 D + + LPF+++ G LGE KQ+P + + + D++RQI VA+++S+ V+N G Sbjct: 354 DDECLELFADLLPFQTSLGTMTLGEFRKQNPVVRYVPSCDQFRQIAQVAASESLAVINAG 413 Query: 426 FIYDAELLSRLPLVDPDVETERLLPEEVSLSFTDITPQERLDYYESVRLADSVLQKFRCQ 485 ++YD ++L+RL + PD E +++ F ++ +ER + E RLAD LQ+F+C Sbjct: 414 YVYDVDILTRLSRIRPDFTLEEFDAVQLADRFEQLSQREREETLEFERLADLTLQRFKCA 473 Query: 486 VQLRRFKPEEIPVLYTLSEESAQWRVLEATKEVSTDALSSVLGSLGATLKDA--AYATLY 543 V++ +F P ++P LY + +R +E ++V+ S +LG L +DA +YA LY Sbjct: 474 VEIAKFLPSDLPSLYVTDGNADFFRSVEQAQDVTEGVWSDMLGDL---TRDAPSSYARLY 530 Query: 544 FNLNNPVIERAFHPAHQKMLPSIIEMLYCNALMMGHYPMNRQEIALLNKGIIQFIDWGL 602 N +N +I+R + +EM+Y AL++GH+P+ + EI LLN+G++ +DW + Sbjct: 531 LNYSNSLIQRICQLGQAEGQRRSVEMVYIQALLLGHFPLKKSEIKLLNEGLLGLLDWAV 589 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.400 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,674,012,906 Number of extensions: 153637324 Number of successful extensions: 393586 Number of sequences better than 1.0e-05: 2129 Number of HSP's gapped: 387788 Number of HSP's successfully gapped: 2136 Length of query: 612 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 470 Effective length of database: 1,722,912,073 Effective search space: 809768674310 Effective search space used: 809768674310 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)