BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0523.0022.p (374 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B7GHH4.1 B7GHH4_ANOFW Leucine dehydrogenase 586 e-165 C5D456.1 C5D456_9BACI Glu/Leu/Phe/Val dehydrogenase 582 e-164 Q75TF3.1 Q75TF3_BACST Leucine dehydrogenase EC=1.4.1.9 576 e-162 A4IQQ5.1 A4IQQ5_GEOTN Leucine dehydrogenase EC=1.4.1.9 575 e-162 P54531.1 DHLE_BACSU Leucine dehydrogenase EC=1.4.1.9 575 e-162 >B7GHH4.1 B7GHH4_ANOFW Leucine dehydrogenase Length = 367 Score = 586 bits (1511), Expect = e-165, Method: Compositional matrix adjust. Identities = 273/364 (75%), Positives = 322/364 (88%) Query: 6 MNLLETMQQSDYEEVVFCQDRQSGLKAIIAIHDTTLGPALGGTRMWAYASEEAALTDVLR 65 M + + M+Q DYE++VFCQD++SGLKAIIAIHDTTLGPALGGTRMW Y SE+AA+ D LR Sbjct: 1 MEIFKYMEQYDYEQLVFCQDKESGLKAIIAIHDTTLGPALGGTRMWMYESEDAAIEDALR 60 Query: 66 LSRGMTYKNAVSGLNLGGGKAVIIGNPKADKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 125 L+RGMTYKNA +GLNLGGGKAVIIG+P+ DKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKAVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 126 DDMNLIHEETEYVTGVSETYGSSGNPSPATAYGVYQGMKAAALEAFGTDSLEGRTVAVQG 185 DM++I+EET+YVTG+S +GSSGNPSP TAYGVY+GMKAAA EAFG+DSLEG+ +AVQG Sbjct: 121 ADMDIIYEETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAKEAFGSDSLEGKVIAVQG 180 Query: 186 VGNVAYHLCSYLHQEGARLIVTDIDKEAVRRALEAYGAKAVSPDDIYSVACDIYAPCALG 245 VGNVAY+LC +LH+EGA+LIVTDI+KEAV+R +E +GA+AV P+DIYSV CDI+APCALG Sbjct: 181 VGNVAYNLCRHLHEEGAKLIVTDINKEAVQRVVEEFGAQAVDPNDIYSVQCDIFAPCALG 240 Query: 246 ATVNDQTISQLKARVIAGAANNQLQEARHGDLLHELGIVYAPDYVLNAGGVIHIADELNG 305 +NDQTI QLKA+VIAGAANNQL+EARHGD++HE+GIVYAPDYV+NAGGVI++ADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGAANNQLREARHGDIIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 306 YNRERAYKKVGEIYRNIRRVFEISAEQGIPSYLAADRLAEERIAGLHASRRTFLQNEQHA 365 YNRERA KKV +IY NI +V EI+ GIP+Y AADRLAEERIA + SR FLQN QH Sbjct: 301 YNRERAMKKVEQIYNNIEKVIEIAKRDGIPTYQAADRLAEERIAKMRQSRSQFLQNGQHI 360 Query: 366 LSRR 369 LSRR Sbjct: 361 LSRR 364 >C5D456.1 C5D456_9BACI Glu/Leu/Phe/Val dehydrogenase Length = 367 Score = 582 bits (1500), Expect = e-164, Method: Compositional matrix adjust. Identities = 271/364 (74%), Positives = 320/364 (87%) Query: 6 MNLLETMQQSDYEEVVFCQDRQSGLKAIIAIHDTTLGPALGGTRMWAYASEEAALTDVLR 65 M L + M+Q DYE+++FCQD++SGLKAIIAIHDTTLGPALGGTRMW Y SEE A+ D LR Sbjct: 1 MELFKYMEQYDYEQLLFCQDKESGLKAIIAIHDTTLGPALGGTRMWMYNSEEEAIEDALR 60 Query: 66 LSRGMTYKNAVSGLNLGGGKAVIIGNPKADKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 125 L+RGMTYKNA +GLNLGGGK VIIG+P+ DKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 126 DDMNLIHEETEYVTGVSETYGSSGNPSPATAYGVYQGMKAAALEAFGTDSLEGRTVAVQG 185 +DM++I++ET+YVTG+S +GSSGNPSPATAYGVY+GMKAAA EAFG+DSLEG+ VAVQG Sbjct: 121 EDMDIIYQETDYVTGISPEFGSSGNPSPATAYGVYRGMKAAAKEAFGSDSLEGKVVAVQG 180 Query: 186 VGNVAYHLCSYLHQEGARLIVTDIDKEAVRRALEAYGAKAVSPDDIYSVACDIYAPCALG 245 VGNVAYHLC +LH+EGA+LIVTDI+KEAV+RA+E +GAKAV P+DIY V CDI+APCALG Sbjct: 181 VGNVAYHLCRHLHEEGAQLIVTDINKEAVQRAVEEFGAKAVDPNDIYGVDCDIFAPCALG 240 Query: 246 ATVNDQTISQLKARVIAGAANNQLQEARHGDLLHELGIVYAPDYVLNAGGVIHIADELNG 305 +NDQTI QLKA+VIAG+ANNQL+EARHGD++HE+GIVYAPDYV+NAGGVI++ADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGSANNQLKEARHGDIIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 306 YNRERAYKKVGEIYRNIRRVFEISAEQGIPSYLAADRLAEERIAGLHASRRTFLQNEQHA 365 YNRERA KK+ +IY NI +VF I+ GIP+Y AADRLAEERI + SR FLQN H Sbjct: 301 YNRERAMKKIEQIYDNIEKVFAIAKRDGIPTYKAADRLAEERIETMRKSRSQFLQNGHHI 360 Query: 366 LSRR 369 LSRR Sbjct: 361 LSRR 364 >Q75TF3.1 Q75TF3_BACST Leucine dehydrogenase EC=1.4.1.9 Length = 367 Score = 576 bits (1484), Expect = e-162, Method: Compositional matrix adjust. Identities = 268/364 (73%), Positives = 316/364 (86%) Query: 6 MNLLETMQQSDYEEVVFCQDRQSGLKAIIAIHDTTLGPALGGTRMWAYASEEAALTDVLR 65 M L + M+ DYE+V+FCQD++SGLKAIIAIHDTTLGPALGGTRMW Y SEE AL D LR Sbjct: 1 MELFKYMETYDYEQVLFCQDKESGLKAIIAIHDTTLGPALGGTRMWMYNSEEEALEDALR 60 Query: 66 LSRGMTYKNAVSGLNLGGGKAVIIGNPKADKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 125 L+RGMTYKNA +GLNLGGGK VIIG+P+ DKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 126 DDMNLIHEETEYVTGVSETYGSSGNPSPATAYGVYQGMKAAALEAFGTDSLEGRTVAVQG 185 DM++I++ET+YVTG+S +GSSGNPSPATAYGVY+GMKAAA EAFG+DSLEG+ VAVQG Sbjct: 121 ADMDIIYQETDYVTGISPEFGSSGNPSPATAYGVYRGMKAAAKEAFGSDSLEGKVVAVQG 180 Query: 186 VGNVAYHLCSYLHQEGARLIVTDIDKEAVRRALEAYGAKAVSPDDIYSVACDIYAPCALG 245 VGNVAYHLC +LH+EGA+LIVTDI+KEAV RA+E +GAKAV P+DIY V CDI+APCALG Sbjct: 181 VGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPNDIYGVECDIFAPCALG 240 Query: 246 ATVNDQTISQLKARVIAGAANNQLQEARHGDLLHELGIVYAPDYVLNAGGVIHIADELNG 305 +NDQTI QLKA+VIAG+ANNQL+E RHGD++HE+GIVYAPDYV+NAGGVI++ADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGSANNQLKEPRHGDIIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 306 YNRERAYKKVGEIYRNIRRVFEISAEQGIPSYLAADRLAEERIAGLHASRRTFLQNEQHA 365 YNRERA KK+ +IY NI +VF I+ IP+Y+AADR+AEERI + +R FLQN H Sbjct: 301 YNRERAMKKIEQIYDNIEKVFAIAKRDNIPTYVAADRMAEERIETMRKARSQFLQNGHHI 360 Query: 366 LSRR 369 LSRR Sbjct: 361 LSRR 364 >A4IQQ5.1 A4IQQ5_GEOTN Leucine dehydrogenase EC=1.4.1.9 Length = 366 Score = 575 bits (1483), Expect = e-162, Method: Compositional matrix adjust. Identities = 269/365 (73%), Positives = 316/365 (86%) Query: 6 MNLLETMQQSDYEEVVFCQDRQSGLKAIIAIHDTTLGPALGGTRMWAYASEEAALTDVLR 65 M L + M+ DYE+V+FCQD++SGLKAIIAIHDTTLGPALGGTRMW Y SEE AL D LR Sbjct: 1 MELFKYMETYDYEQVLFCQDKESGLKAIIAIHDTTLGPALGGTRMWMYNSEEEALEDALR 60 Query: 66 LSRGMTYKNAVSGLNLGGGKAVIIGNPKADKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 125 L+RGMTYKNA +GLNLGGGK VIIG+P+ DKNEAMFRAFGR+IQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEAMFRAFGRFIQGLNGRYITAEDVGTTV 120 Query: 126 DDMNLIHEETEYVTGVSETYGSSGNPSPATAYGVYQGMKAAALEAFGTDSLEGRTVAVQG 185 DM++I++ET+YVTG+S +GSSGNPSP TAYGVY+GMKAA EAFG+DSLEG+ VAVQG Sbjct: 121 ADMDIIYQETDYVTGISPEFGSSGNPSPMTAYGVYRGMKAAVKEAFGSDSLEGKVVAVQG 180 Query: 186 VGNVAYHLCSYLHQEGARLIVTDIDKEAVRRALEAYGAKAVSPDDIYSVACDIYAPCALG 245 VGNVAYHLC +LH+EGA+LIVTDI+KEAV RA+E +GAKAV P+DIY V CDI+APCALG Sbjct: 181 VGNVAYHLCRHLHEEGAQLIVTDINKEAVARAVEEFGAKAVDPNDIYGVECDIFAPCALG 240 Query: 246 ATVNDQTISQLKARVIAGAANNQLQEARHGDLLHELGIVYAPDYVLNAGGVIHIADELNG 305 +NDQTI QLKA+VIAG+ANNQL+EARHGD++HE+GIVYAPDYV+NAGGVI++ADEL G Sbjct: 241 GIINDQTIPQLKAKVIAGSANNQLREARHGDIIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 306 YNRERAYKKVGEIYRNIRRVFEISAEQGIPSYLAADRLAEERIAGLHASRRTFLQNEQHA 365 YNRERA KKV +IY NI +VF I+ IP+Y+AADR+AEERI + SR FLQN H Sbjct: 301 YNRERAMKKVEQIYDNIEKVFAIAKRDNIPTYVAADRMAEERIETMRKSRSQFLQNGHHI 360 Query: 366 LSRRA 370 LSRR+ Sbjct: 361 LSRRS 365 >P54531.1 DHLE_BACSU Leucine dehydrogenase EC=1.4.1.9 Length = 364 Score = 575 bits (1481), Expect = e-162, Method: Compositional matrix adjust. Identities = 273/364 (75%), Positives = 314/364 (86%) Query: 6 MNLLETMQQSDYEEVVFCQDRQSGLKAIIAIHDTTLGPALGGTRMWAYASEEAALTDVLR 65 M L + M++ DYE++VFCQD QSGLKAIIAIHDTTLGPALGGTRMW Y +EEAA+ D LR Sbjct: 1 MELFKYMEKYDYEQLVFCQDEQSGLKAIIAIHDTTLGPALGGTRMWTYENEEAAIEDALR 60 Query: 66 LSRGMTYKNAVSGLNLGGGKAVIIGNPKADKNEAMFRAFGRYIQGLNGRYITAEDVGTTE 125 L+RGMTYKNA +GLNLGGGK VIIG+P+ DKNE MFRAFGRYIQGLNGRYITAEDVGTT Sbjct: 61 LARGMTYKNAAAGLNLGGGKTVIIGDPRKDKNEEMFRAFGRYIQGLNGRYITAEDVGTTV 120 Query: 126 DDMNLIHEETEYVTGVSETYGSSGNPSPATAYGVYQGMKAAALEAFGTDSLEGRTVAVQG 185 +DM++IH+ET+YVTG+S +GSSGNPSP TAYGVY+GMKAAA AFGTDSLEG+T+AVQG Sbjct: 121 EDMDIIHDETDYVTGISPAFGSSGNPSPVTAYGVYRGMKAAAKAAFGTDSLEGKTIAVQG 180 Query: 186 VGNVAYHLCSYLHQEGARLIVTDIDKEAVRRALEAYGAKAVSPDDIYSVACDIYAPCALG 245 VGNVAY+LC +LH+EGA LIVTDI+K++V+RA+E +GA+AV PDDIYS CDIYAPCALG Sbjct: 181 VGNVAYNLCRHLHEEGANLIVTDINKQSVQRAVEDFGARAVDPDDIYSQDCDIYAPCALG 240 Query: 246 ATVNDQTISQLKARVIAGAANNQLQEARHGDLLHELGIVYAPDYVLNAGGVIHIADELNG 305 AT+ND TI QLKA+VIAGAANNQL+E RHGD +HE+GIVYAPDYV+NAGGVI++ADEL G Sbjct: 241 ATINDDTIKQLKAKVIAGAANNQLKETRHGDQIHEMGIVYAPDYVINAGGVINVADELYG 300 Query: 306 YNRERAYKKVGEIYRNIRRVFEISAEQGIPSYLAADRLAEERIAGLHASRRTFLQNEQHA 365 YN ERA KKV IY NI RV EIS GIP+YLAADRLAEERI + SR FLQN Sbjct: 301 YNAERALKKVEGIYGNIERVLEISQRDGIPAYLAADRLAEERIERMRRSRSQFLQNGHSV 360 Query: 366 LSRR 369 LSRR Sbjct: 361 LSRR 364 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.133 0.376 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,130,398,504 Number of extensions: 89615134 Number of successful extensions: 280749 Number of sequences better than 1.0e-05: 1771 Number of HSP's gapped: 277930 Number of HSP's successfully gapped: 1773 Length of query: 374 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 237 Effective length of database: 1,770,017,148 Effective search space: 419494064076 Effective search space used: 419494064076 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)