BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0520.0020.p (260 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3HL83.1 C3HL83_BACTU GTP cyclohydrolase-2 346 1e-93 C3H3R5.1 C3H3R5_BACTU GTP cyclohydrolase-2 345 3e-93 Q4V1U4.1 Q4V1U4_BACCZ GTP cyclohydrolase-2 EC=3.5.4.25 344 4e-93 C3G5N1.1 C3G5N1_BACTU GTP cyclohydrolase-2 344 4e-93 B7H6C8.1 B7H6C8_BACC4 GTP cyclohydrolase-2 EC=3.5.4.25 344 4e-93 >C3HL83.1 C3HL83_BACTU GTP cyclohydrolase-2 Length = 245 Score = 346 bits (887), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 163/247 (65%), Positives = 196/247 (79%), Gaps = 7/247 (2%) Query: 1 MIKPDILSILQNKIKRITMDDSTNILVGPITLPVNLDGETVTFKWYSWLKATDEELQGGD 60 M+ D + +L++KI+ I D+ LVGPI LP+NL GET F+WYSWL+ ++ Sbjct: 1 MVTTDTIHMLEDKIQFIHQDEKDIYLVGPIKLPINLYGETKVFQWYSWLQCSE------- 53 Query: 61 SKEATELLISRLSSMNLAEGQQSSVLVYGDFADSDEALIRMHSICHTGDIFGSKRCDCGF 120 + E +I +LSS+NLA+ QQSSVLVYGDF +S++ALIRMHSICHTGDIFGSKRCDCGF Sbjct: 54 VTNSVEGIIEKLSSINLADMQQSSVLVYGDFENSEDALIRMHSICHTGDIFGSKRCDCGF 113 Query: 121 QLRQSMKMIAQHGSGALFYLANHEGRGIGLFSKAMAYILQEEGYDTVEANLELGFADDSR 180 QL+QS++MI +HGSGALFYLANHEGRGIGLFSKAM Y+LQE G DTVEANL+LGF DD R Sbjct: 114 QLKQSLQMITEHGSGALFYLANHEGRGIGLFSKAMTYLLQENGLDTVEANLKLGFEDDVR 173 Query: 181 DYRDAISVLQHLRSKPVTLITNNPKKMEALKAAGMNTGKRIPLWGDVSVFNEKYLRTKVS 240 +Y D I VL+ LRSKPV LITNNPKK+EAL+ AG+N R PLWGDVS FNEKYL+TK+ Sbjct: 174 NYDDTIEVLKALRSKPVKLITNNPKKLEALQKAGLNVTSREPLWGDVSEFNEKYLQTKIQ 233 Query: 241 RSGHLEA 247 RSGH E Sbjct: 234 RSGHFEG 240 >C3H3R5.1 C3H3R5_BACTU GTP cyclohydrolase-2 Length = 245 Score = 345 bits (884), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 165/247 (66%), Positives = 196/247 (79%), Gaps = 7/247 (2%) Query: 1 MIKPDILSILQNKIKRITMDDSTNILVGPITLPVNLDGETVTFKWYSWLKATDEELQGGD 60 M+ D + +L++KI+ I D LVGPI LP+NL GET F+WYSWL+ + +G + Sbjct: 1 MVTTDTIHMLEDKIQFIHQDGKDIYLVGPIKLPINLYGETKVFQWYSWLQCS----EGTN 56 Query: 61 SKEATELLISRLSSMNLAEGQQSSVLVYGDFADSDEALIRMHSICHTGDIFGSKRCDCGF 120 S E +I +LSS+NLA+ QQSSVLVYGDF +S++ALIRMHSICHTGDIFGSKRCDCGF Sbjct: 57 SVEG---VIEKLSSINLADMQQSSVLVYGDFENSEDALIRMHSICHTGDIFGSKRCDCGF 113 Query: 121 QLRQSMKMIAQHGSGALFYLANHEGRGIGLFSKAMAYILQEEGYDTVEANLELGFADDSR 180 QL+QS++MI +HGSGALFYLANHEGRGIGLFSKAM Y+LQE G DTVEANL LGF DD R Sbjct: 114 QLKQSLQMITEHGSGALFYLANHEGRGIGLFSKAMTYLLQENGLDTVEANLNLGFEDDVR 173 Query: 181 DYRDAISVLQHLRSKPVTLITNNPKKMEALKAAGMNTGKRIPLWGDVSVFNEKYLRTKVS 240 +Y D I VL+ LRSKPV LITNNPKK+EAL+ AG+N R PLWGDVS FNEKYL+TK+ Sbjct: 174 NYDDTIEVLKALRSKPVKLITNNPKKLEALQKAGLNVTSREPLWGDVSEFNEKYLQTKIQ 233 Query: 241 RSGHLEA 247 RSGH E Sbjct: 234 RSGHFEG 240 >Q4V1U4.1 Q4V1U4_BACCZ GTP cyclohydrolase-2 EC=3.5.4.25 Length = 245 Score = 344 bits (883), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 163/247 (65%), Positives = 194/247 (78%), Gaps = 7/247 (2%) Query: 1 MIKPDILSILQNKIKRITMDDSTNILVGPITLPVNLDGETVTFKWYSWLKATDEELQGGD 60 M+ D + +L++KI+ I D LVGPI LP+NL GET F+WYSWL+ ++ Sbjct: 1 MVTTDTIHMLEDKIQFIHQDGKDIYLVGPIKLPINLYGETKVFQWYSWLQCSE------- 53 Query: 61 SKEATELLISRLSSMNLAEGQQSSVLVYGDFADSDEALIRMHSICHTGDIFGSKRCDCGF 120 + E +I +LSS+NLA+ QQSSVLVYGDF +S++ALIRMHSICHTGDIFGSKRCDCGF Sbjct: 54 VTNSVEGMIEKLSSINLADMQQSSVLVYGDFENSEDALIRMHSICHTGDIFGSKRCDCGF 113 Query: 121 QLRQSMKMIAQHGSGALFYLANHEGRGIGLFSKAMAYILQEEGYDTVEANLELGFADDSR 180 QL+QS++MI +HGSGALFYLANHEGRGIGLFSKAM Y+LQE G DTVEANL LGF DD R Sbjct: 114 QLKQSLQMITEHGSGALFYLANHEGRGIGLFSKAMTYLLQENGLDTVEANLNLGFEDDVR 173 Query: 181 DYRDAISVLQHLRSKPVTLITNNPKKMEALKAAGMNTGKRIPLWGDVSVFNEKYLRTKVS 240 +Y D I VL+ LRSKPV LITNNPKK+EAL+ AG+N R PLWGDVS FNEKYL+TK+ Sbjct: 174 NYDDTIEVLKALRSKPVKLITNNPKKLEALQKAGLNVTSREPLWGDVSEFNEKYLQTKIQ 233 Query: 241 RSGHLEA 247 RSGH E Sbjct: 234 RSGHFEG 240 >C3G5N1.1 C3G5N1_BACTU GTP cyclohydrolase-2 Length = 245 Score = 344 bits (883), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 165/247 (66%), Positives = 196/247 (79%), Gaps = 7/247 (2%) Query: 1 MIKPDILSILQNKIKRITMDDSTNILVGPITLPVNLDGETVTFKWYSWLKATDEELQGGD 60 M+ D + +L++KI+ I D LVGPI LP+NL GET F+WYSWL+ + +G + Sbjct: 1 MVTTDTIHMLEDKIQFIHQDGKDIYLVGPIKLPINLYGETKVFQWYSWLQCS----EGTN 56 Query: 61 SKEATELLISRLSSMNLAEGQQSSVLVYGDFADSDEALIRMHSICHTGDIFGSKRCDCGF 120 S E +I +LSS+NLA+ QQSSVLVYGDF +S++ALIRMHSICHTGDIFGSKRCDCGF Sbjct: 57 SVEG---IIEKLSSINLADMQQSSVLVYGDFENSEDALIRMHSICHTGDIFGSKRCDCGF 113 Query: 121 QLRQSMKMIAQHGSGALFYLANHEGRGIGLFSKAMAYILQEEGYDTVEANLELGFADDSR 180 QL+QS+ MI +HGSGALFYLANHEGRGIGLFSKAM Y+LQE G DTVEANL+LGF DD R Sbjct: 114 QLKQSLHMITEHGSGALFYLANHEGRGIGLFSKAMTYLLQENGLDTVEANLKLGFEDDVR 173 Query: 181 DYRDAISVLQHLRSKPVTLITNNPKKMEALKAAGMNTGKRIPLWGDVSVFNEKYLRTKVS 240 +Y D I VL+ LRSKPV LITNNPKK+EAL+ AG+N R PLWGDVS FNEKYL+TK+ Sbjct: 174 NYDDTIEVLKALRSKPVKLITNNPKKLEALQKAGLNVTSREPLWGDVSEFNEKYLQTKIQ 233 Query: 241 RSGHLEA 247 RSGH E Sbjct: 234 RSGHFEG 240 >B7H6C8.1 B7H6C8_BACC4 GTP cyclohydrolase-2 EC=3.5.4.25 Length = 245 Score = 344 bits (883), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 163/247 (65%), Positives = 194/247 (78%), Gaps = 7/247 (2%) Query: 1 MIKPDILSILQNKIKRITMDDSTNILVGPITLPVNLDGETVTFKWYSWLKATDEELQGGD 60 M+ D + +L++KI+ I D LVGPI LP+NL GET F+WYSWL+ ++ Sbjct: 1 MVTTDTIHMLEDKIQFIHQDGKDIYLVGPIKLPINLYGETKVFQWYSWLQCSE------- 53 Query: 61 SKEATELLISRLSSMNLAEGQQSSVLVYGDFADSDEALIRMHSICHTGDIFGSKRCDCGF 120 + E +I +LSS+NLA+ QQSSVLVYGDF +S++ALIRMHSICHTGDIFGSKRCDCGF Sbjct: 54 VTNSVEGIIEKLSSINLADMQQSSVLVYGDFENSEDALIRMHSICHTGDIFGSKRCDCGF 113 Query: 121 QLRQSMKMIAQHGSGALFYLANHEGRGIGLFSKAMAYILQEEGYDTVEANLELGFADDSR 180 QL+QS++MI +HGSGALFYLANHEGRGIGLFSKAM Y+LQE G DTVEANL LGF DD R Sbjct: 114 QLKQSLQMITEHGSGALFYLANHEGRGIGLFSKAMTYLLQENGLDTVEANLNLGFEDDVR 173 Query: 181 DYRDAISVLQHLRSKPVTLITNNPKKMEALKAAGMNTGKRIPLWGDVSVFNEKYLRTKVS 240 +Y D I VL+ LRSKPV LITNNPKK+EAL+ AG+N R PLWGDVS FNEKYL+TK+ Sbjct: 174 NYDDTIEVLKALRSKPVKLITNNPKKLEALQKAGLNVTSREPLWGDVSEFNEKYLQTKIQ 233 Query: 241 RSGHLEA 247 RSGH E Sbjct: 234 RSGHFEG 240 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.390 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,496,166,909 Number of extensions: 58850088 Number of successful extensions: 144624 Number of sequences better than 1.0e-05: 1402 Number of HSP's gapped: 143292 Number of HSP's successfully gapped: 1402 Length of query: 260 Length of database: 3,060,696,203 Length adjustment: 133 Effective length of query: 127 Effective length of database: 1,807,701,208 Effective search space: 229578053416 Effective search space used: 229578053416 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 130 (54.7 bits)