BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0520.0007.p (615 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KIS5.1 B3KIS5_9BACI Sensor protein EC=2.7.13.3 524 e-146 B1D881.1 B1D881_9BACL Sensor protein EC=2.7.13.3 429 e-118 A3IAM7.1 A3IAM7_9BACI Sensor protein EC=2.7.13.3 419 e-115 B1HNT3.1 B1HNT3_LYSSC Sensor protein EC=2.7.13.3 415 e-114 Q6HMG5.1 Q6HMG5_BACHK Sensor protein EC=2.7.13.3 335 1e-89 >B3KIS5.1 B3KIS5_9BACI Sensor protein EC=2.7.13.3 Length = 893 Score = 524 bits (1349), Expect = e-146, Method: Compositional matrix adjust. Identities = 268/588 (45%), Positives = 382/588 (64%), Gaps = 7/588 (1%) Query: 14 LRIRSKIALGYVMIXXXXXXXXXVVAGRITDLEKETVFLSDHDMKVHELTYQIEKDVLDM 73 IRSKI +GY++I +V+ RI+ L++E F+ HD++VH LT++IEK++L+M Sbjct: 7 FNIRSKIVIGYLLILMCLGAFLWIVSDRISSLQQEADFIEKHDIEVHNLTHEIEKNMLEM 66 Query: 74 ETGQRGYALTGESSYLTPYDTGITEWKIHYTGLSGLINDNPDQSKILSNIQNNIEHWIES 133 ETGQRGY +TG+ +YL P++ ++ W+I+Y L L++DN +Q+ L NI+ NI+ WI + Sbjct: 67 ETGQRGYVITGDETYLEPFNQALSSWQINYNKLYKLVSDNSEQANHLENIKENIKEWITN 126 Query: 134 AGQYIVDLKRNGQTQAVNAFFHNDSGKVIIDSIRSQFDYFRDNERKLTSERIANLKASND 193 AGQ V L + GQ + FF ND GK ++SI F FR ER+LT+ RI +K SN Sbjct: 127 AGQPAVQLMQLGQDEEALHFFINDPGKQAMNSIHELFLSFRSKERELTTSRIEEMKESNA 186 Query: 194 KLLVTMYILWGLVALLAALITYLISASIVKPLRSVIQAIHTIASGGNMSERISVKSLDEI 253 +LL TMY+LW AL+ ++IS SIVKP+ V I I +GGN+S+RI V S DE+ Sbjct: 187 RLLYTMYLLWAGAALITICAAWVISKSIVKPINQVTNVISDIVNGGNISQRIHVHSNDEV 246 Query: 254 NDLGNATNDLLDTVQRQQWSSEQLALMSVALQETTDLPLLCRTFMNRLSVILELQYGAVY 313 L + TN+LL V RQ W+ + +++MS LQ + + + F+++L++I++L YGAV+ Sbjct: 247 RQLADTTNELLAQVGRQNWAKDHVSVMSTILQSSDRVETAVQFFIHKLALIMKLPYGAVF 306 Query: 314 VLNGNKEYKRMYSYAGSEQQEIEFGKSTIRPGEGLVGQCAADMRMIRINNLPEDYISINS 373 + E + ++A + + + PGEGLVGQC + RMI ++++P +Y+ I S Sbjct: 307 ITRSGSELVKAAAFADPDGEPWNKVRDRFLPGEGLVGQCMLEQRMIILDDIPPNYVRIES 366 Query: 374 GLGRSAPKFAVIAPILFENKTLAVLETASLTQWAPHHLELFNELLKMLGVTLNSVLTRME 433 GLG + P ++AP++FE + L V+E A + ++L +L LGVT+NS+ ++ME Sbjct: 367 GLGDAEPSTLLLAPVMFEGQVLGVIELAKFQPFDELEIQLIEQLNFQLGVTMNSIQSKME 426 Query: 434 IQQLYSESQTMNXXXXXXXXXXXXXXXXXXXXXXXXXNHTQELLTLNRELEHQKSVAENA 493 IQQLY ESQT+N H+ E+ LN L QK A A Sbjct: 427 IQQLYHESQTLN-------EELQSQTEELQAQTEELQTHSVEMHLLNERLGAQKEAALIA 479 Query: 494 AAQLEKYNEQLELSSRYKSEFLANMSHELRTPLNSMLILSQLLTENRNDSLTEEEQGYAE 553 A++LEKY ++LE SS+YKS+FLANMSHELRTPLNSMLILSQ+L EN+ +LTEEEQ YA Sbjct: 480 ASELEKYAKELEKSSKYKSQFLANMSHELRTPLNSMLILSQILAENKQGNLTEEEQHYAT 539 Query: 554 VIHSSGSELLGMINDILDLSKVEAGKMTVERDPVNLTELPSILYGYFN 601 VIH+SGSELL +INDILDLSKVEAGKM +E D VNLTELP ++ GYF+ Sbjct: 540 VIHNSGSELLNLINDILDLSKVEAGKMQIEMDLVNLTELPELMEGYFS 587 >B1D881.1 B1D881_9BACL Sensor protein EC=2.7.13.3 Length = 890 Score = 429 bits (1102), Expect = e-118, Method: Compositional matrix adjust. Identities = 240/600 (40%), Positives = 353/600 (58%), Gaps = 29/600 (4%) Query: 10 QAWSLRIRSKIALGYVMIXXXXXXXXXVVAGRITDLEKETVFLSDHDMKVHELTYQIEKD 69 +A IR+KIA+GY +I V RI L+ E ++ D++VH L I+ D Sbjct: 3 RALKFNIRTKIAIGYFLILICLGASIVTVTDRIEALQNEVETITTRDVEVHNLIASIQYD 62 Query: 70 VLDMETGQRGYALTGESSYLTPYDTGITEWKIHYTGLSGLINDNPDQSKILSNIQNNIEH 129 + MET QRGY +TGE SYL PYD G ++W+ +Y+ L ++DNP K L I+ +I+ Sbjct: 63 AISMETAQRGYIITGEKSYLDPYDKGKSQWESNYSSLYAYVSDNPSTQKQLEEIKLSIQE 122 Query: 130 WIESAGQYIVDLKRNGQTQAVNAFFHNDSGKVIIDSIRSQFDYFRDNERKLTSERIANLK 189 WI A + + +K+ G+ + AFF +D GK +D +RS+FD + E + T I +L+ Sbjct: 123 WINKAAEPTIAMKQEGREADIIAFFQDDVGKQQMDDLRSKFDAIGNQEVQATKLHIMDLE 182 Query: 190 ASNDKLLVTMYILWGLVALLAALITYLISASIVKPLRSVIQAIHTIA-SGGNMSERISVK 248 N L V +Y+L +++ +I +S SIVK ++ V++ I IA SGGN++ RI V Sbjct: 183 NKNRILTVGIYLLLLAATIISFMIVSFVSGSIVKTIKQVVETIKEIASSGGNLATRIKVN 242 Query: 249 SLDEINDLGNATNDLLDTVQRQQWSSEQLALMSVALQETTDLPLLCRTFMNRLSVILELQ 308 + DEI DLG+ATN+LL +++ W ++A ++ Q DL L RTF+ +++ ++ Sbjct: 243 TRDEIKDLGDATNELLASLEANSWIQAKVAEVATMTQGINDLQELARTFLTKVAPMVNAS 302 Query: 309 YGAVYVLNGNKEYKRMYSYAGSEQQEIEFGKSTIRPGEGLVGQCAADMRMIRINNLPEDY 368 YG Y+ G + +R+ A + GKS IR GEGL GQCA + R+ IN + Sbjct: 303 YGVFYIRKGAGDQQRLEKLASYASSGEDGGKSDIRFGEGLAGQCAVEKRIFLINQTKDHR 362 Query: 369 ISINSGLGRSAPKFAVIAPILFENKTLAVLETASLTQWAPHHLELFNELLKMLGVTLNSV 428 I++GL + P+ +I PI +E++ AV+E ASL + HL+L E+ K G+ +N+V Sbjct: 363 PLISTGLFQLEPRSILIVPIEYEDRLEAVIEFASLESFTSQHLKLMEEVEKDFGIAVNNV 422 Query: 429 LTRMEIQQLYSESQTMNXXXXXXXXXXXXXXXXXXXXXXXXXNHTQELLTLNRELEHQKS 488 RME+++L SESQ + +E+ LE Q Sbjct: 423 AGRMEVERLLSESQVLTEELQM---------------------QQEEMRMTTEHLEEQYL 461 Query: 489 VAEN-------AAAQLEKYNEQLELSSRYKSEFLANMSHELRTPLNSMLILSQLLTENRN 541 VAE A +LE Y+EQLE SS+YKS FLANMSHELRTPLNS+LILSQLL EN N Sbjct: 462 VAEQKTKELEKAKEELEDYSEQLEKSSQYKSNFLANMSHELRTPLNSILILSQLLAENEN 521 Query: 542 DSLTEEEQGYAEVIHSSGSELLGMINDILDLSKVEAGKMTVERDPVNLTELPSILYGYFN 601 +L E+E+GYA+VIH+SG++LL +I+DILDLSK+EAGK+ + D VNLTE+P ++ FN Sbjct: 522 HTLNEDEEGYAKVIHTSGTDLLKLIDDILDLSKIEAGKVILTVDEVNLTEIPELMKLTFN 581 >A3IAM7.1 A3IAM7_9BACI Sensor protein EC=2.7.13.3 Length = 915 Score = 419 bits (1076), Expect = e-115, Method: Compositional matrix adjust. Identities = 234/596 (39%), Positives = 349/596 (58%), Gaps = 17/596 (2%) Query: 6 LLNKQAWSLRIRSKIALGYVMIXXXXXXXXXVVAGRITDLEKETVFLSDHDMKVHELTYQ 65 +LNK + L IRSKI LGY++I ++ +IT L+KE F+ +D V LT Sbjct: 1 MLNK--FKLGIRSKITLGYIIIILCLLASVIILNNQITSLQKERNFIIKYDSNVKTLTND 58 Query: 66 IEKDVLDMETGQRGYALTGESSYLTPYDTGITEWKIHYTGLSGLINDNPDQSKILSNIQN 125 IEK +LDME+ QR + +TGE SYL PYD G WKI + L + D P Q + L I+ Sbjct: 59 IEKYILDMESSQRAFIITGEPSYLEPYDNGAENWKIDFNDLYQQMKDKPTQQEKLKEIEE 118 Query: 126 NIEHWIESAGQYIVDLKRNGQTQAVNAFFHNDSGKVIIDSIRSQFDYFRDNERKLTSERI 185 IEHWIE+ G + K++G T+A+ FF D+G+ ++ +R FD FR E T + Sbjct: 119 TIEHWIETTGGPTIQYKKDGNTKALTEFFKVDNGRQDMEKMRKLFDAFRATENTYTQAKA 178 Query: 186 ANLKASNDKLLVTMYILWGLVALLAALITYLISASIVKPLRSVIQAIHTI-ASGGNMSER 244 A L N +L ++ + V+++A +I IS SIVK + V Q I + A+ G+ R Sbjct: 179 AQLDKQNSQLTSGLFGILIFVSVIAIVIASGISRSIVKTITEVTQTIQEMAATKGDFKRR 238 Query: 245 ISVKSLDEINDLGNATNDLLDTVQRQQWSSEQLALMSVALQETTDLPLLCRTFMNRLSVI 304 I V + DEIN+L +ATN LL++V++++W +A + Q + + L TF++ ++ Sbjct: 239 IHVNTNDEINELADATNLLLESVEKREWLQTNIADIVTKYQGISAITKLAETFLSEMAQK 298 Query: 305 LELQYGAVYVLNGNKEYKRMYSYAGSEQQEIEFGKSTIRPGEGLVGQCAADMRMIRINNL 364 E GA YV +E A E G+ + + G+GL+GQCA + R++ +N+ Sbjct: 299 TEASLGAFYVREEAEEQVLFMKKAAFADGEDGVGRESFKVGQGLIGQCALEKRVLFYDNI 358 Query: 365 PEDYISINSGLGRSAPKFAVIAPILFENKTLAVLETASLTQWAPHHLELFNELLKMLGVT 424 P+DY I +GLG P+ ++ P++FEN+ +AV+E A++T++ EL ++ + G+T Sbjct: 359 PQDYRLIRTGLGEIRPQHILLIPVIFENEVIAVVELATMTKFNALQQELMKQVTETFGLT 418 Query: 425 LNSVLTRMEIQQLYSESQTMNXXXXXXXXXXXXXXXXXXXXXXXXXNHTQELLTLNRELE 484 +N VL RMEI +L +ES+ M T+EL +N +LE Sbjct: 419 VNGVLGRMEIVRLLNESRAMTEELQVQSEELQTQSEELQM-------QTEELTMINEQLE 471 Query: 485 HQKSVAENAAAQLEKYNEQLE-------LSSRYKSEFLANMSHELRTPLNSMLILSQLLT 537 + AE + +LEK ++LE L+S YKSEFLANMSHELRTPLNS+LILS++L Sbjct: 472 ERTKEAETKSRELEKAKQELEESAEQLILNSNYKSEFLANMSHELRTPLNSILILSEMLA 531 Query: 538 ENRNDSLTEEEQGYAEVIHSSGSELLGMINDILDLSKVEAGKMTVERDPVNLTELP 593 EN D LT+EE +A+VIHSSG +LL +INDILDLSKVEAGK+ + + VN++E+P Sbjct: 532 ENNQDHLTDEEAEFAKVIHSSGEDLLALINDILDLSKVEAGKLDIIFNEVNVSEVP 587 >B1HNT3.1 B1HNT3_LYSSC Sensor protein EC=2.7.13.3 Length = 916 Score = 415 bits (1067), Expect = e-114, Method: Compositional matrix adjust. Identities = 232/596 (38%), Positives = 349/596 (58%), Gaps = 17/596 (2%) Query: 6 LLNKQAWSLRIRSKIALGYVMIXXXXXXXXXVVAGRITDLEKETVFLSDHDMKVHELTYQ 65 +LNK L IRSKI LGY++I ++ +IT L+KE F+ +D V LT Sbjct: 1 MLNK--LKLGIRSKITLGYIIIILCLLASVIILNNQITSLQKERNFIIKYDSNVKTLTND 58 Query: 66 IEKDVLDMETGQRGYALTGESSYLTPYDTGITEWKIHYTGLSGLINDNPDQSKILSNIQN 125 IEK +LDME+ QR + +TGE SYL PYD G WKI + L + D P Q + L I+ Sbjct: 59 IEKYILDMESSQRAFIITGEPSYLEPYDNGAENWKIDFNDLYQQMKDKPTQQEKLKEIEE 118 Query: 126 NIEHWIESAGQYIVDLKRNGQTQAVNAFFHNDSGKVIIDSIRSQFDYFRDNERKLTSERI 185 I+HW+E+ G + K++G T+A+ FF D+G+ ++ +R FD FR E T + Sbjct: 119 TIDHWVETTGGPTIQYKKDGNTKALTEFFKVDNGRQDMEKMRKLFDAFRATENTYTQAKA 178 Query: 186 ANLKASNDKLLVTMYILWGLVALLAALITYLISASIVKPLRSVIQAIHTI-ASGGNMSER 244 A L N +L ++ + LV+++A +I IS SIVK + V Q I + A+ G+ R Sbjct: 179 AQLDKQNSQLTSGLFGILILVSVIAIVIASGISRSIVKTITEVTQTIQEMAATKGDFKRR 238 Query: 245 ISVKSLDEINDLGNATNDLLDTVQRQQWSSEQLALMSVALQETTDLPLLCRTFMNRLSVI 304 I V + DEIN+L +ATN LL++V++++W +A + Q + + L TF++ ++ Sbjct: 239 IHVNTNDEINELADATNILLESVEKREWLQTNIADIVTKYQGISAITKLAETFLSEMAQK 298 Query: 305 LELQYGAVYVLNGNKEYKRMYSYAGSEQQEIEFGKSTIRPGEGLVGQCAADMRMIRINNL 364 + GA YV +E A + G + + G+GL+GQCA + R++ +N+ Sbjct: 299 TQASLGAFYVREEAEEQVLFIKKAAFADGDDRVGMESFKVGQGLIGQCALEKRVLFYDNI 358 Query: 365 PEDYISINSGLGRSAPKFAVIAPILFENKTLAVLETASLTQWAPHHLELFNELLKMLGVT 424 P+DY I +GLG PK ++ P++FEN+ +AV+E A++T++ EL ++ + G+T Sbjct: 359 PQDYRLIRTGLGEIRPKHILLIPVIFENEVIAVVELATMTKFNALQQELVKQVTETFGLT 418 Query: 425 LNSVLTRMEIQQLYSESQTMNXXXXXXXXXXXXXXXXXXXXXXXXXNHTQELLTLNRELE 484 +N VL RMEI +L +ES+ M T+EL +N +LE Sbjct: 419 VNGVLGRMEIVRLLNESRAMTEELQVQSEELQTQSEELQM-------QTEELTMINEQLE 471 Query: 485 HQKSVAENAAAQLEKYNEQLE-------LSSRYKSEFLANMSHELRTPLNSMLILSQLLT 537 + AE+ + +LEK ++LE L+S YKSEFLANMSHELRTPLNS+LILS++L Sbjct: 472 ERTKEAESKSRELEKAKQELEESAEQLILNSNYKSEFLANMSHELRTPLNSILILSEMLA 531 Query: 538 ENRNDSLTEEEQGYAEVIHSSGSELLGMINDILDLSKVEAGKMTVERDPVNLTELP 593 EN D LT+EE +A+VIHSSG +LL +INDILDLSKVEAGK+ + + VN++E+P Sbjct: 532 ENSQDHLTDEETEFAKVIHSSGEDLLALINDILDLSKVEAGKLDIIFNEVNMSEVP 587 >Q6HMG5.1 Q6HMG5_BACHK Sensor protein EC=2.7.13.3 Length = 896 Score = 335 bits (858), Expect = 1e-89, Method: Compositional matrix adjust. Identities = 205/599 (34%), Positives = 332/599 (55%), Gaps = 22/599 (3%) Query: 9 KQAWSLRIRSKIALGYVMIXXXXXXXXXVVAGRITDLEKETVFLSDHDMKVHELTYQIEK 68 K IR KI GY++I V+ +I++L+K F+ DHD KV LT Q+EK Sbjct: 2 KSKAKFSIRYKIMAGYLVIILFLLISFIVLNNQISNLQKSRNFIIDHDFKVLNLTNQVEK 61 Query: 69 DVLDMETGQRGYALTGESSYLTPYDTGITEWKIHYTGLSGLINDNPDQSKILSNIQNNIE 128 D+L +E +G+ + ++YL ++ +++ HY L L+ DNP Q + L I NI Sbjct: 62 DLLTIENKAKGFITSNNANYLQSLNSAERDYEKHYHNLFSLLEDNPSQQEKLKEINGNIT 121 Query: 129 HWIESAGQYIVDLKRNGQTQAVNAFFHNDSGKVIIDSIRSQFDYFRDNERKLTSERIANL 188 +W+ ++ + + Q ++ I S++SQ FR E +LT +R A L Sbjct: 122 NWMNKEIHPLIANHNSNKIQEIDT--------TEIQSLQSQLTDFRSTEEQLTKKRAAQL 173 Query: 189 KASNDKLLVTMYILWGLVALLAALITYLISASIVKPLRSVIQAIHTIASGGNMSERISVK 248 N+KL + +Y L L++ ++ +++ IS SI K +++VIQAI +I+S ++ERI V Sbjct: 174 DTKNNKLELWLYSLLFLLSCISIIVSLYISNSITKTIKNVIQAIKSISSKEKITERIHVN 233 Query: 249 SLDEINDLGNATNDLLDTVQRQQWSSEQLALMSVALQETTDLPLLCRTFMNRLSVILELQ 308 + DEI DL + TN LLD + +++W ++A + + Q + + +L ++ + + Sbjct: 234 THDEIKDLAHTTNHLLDEISKREWLQTEIAELILMYQGVSSIEMLGNKILSGIIQKTQTS 293 Query: 309 YGAVYVLNGNKEYKRMYSYAGSEQQEIEFGKSTIRPGEGLVGQCAADMRMIRINNLPEDY 368 GA YV +E A Q I+ GK +I+ GEG +GQ A + + + ++PE++ Sbjct: 294 CGAFYVREEVEETVYFVKKASFADQGIDIGKQSIKMGEGFIGQSALEKKSFILRDIPEEF 353 Query: 369 ISINSGLGRSAPKFAVIAPILFENKTLAVLETASLTQWAPHHLELFNELLKMLGVTLNSV 428 + +GL PK ++ P+LFE++ +AV+E S+T + H +L ++ + LG+T++S+ Sbjct: 354 RYVTTGLLEIRPKNLLVIPVLFEDEVIAVMELVSVTDISDLHQDLIHQTVDNLGLTIHSI 413 Query: 429 LTRMEIQQLYSESQTMNXXXXXXXXXXXXXXXXXXXXXXXXXNHTQELLTLNRELEHQKS 488 + RM IQ L ESQ M +EL T N +LE + Sbjct: 414 MGRMRIQTLLHESQAMTEELQVQSEELQTQAEELQM-------QAEELRTTNEQLESRTE 466 Query: 489 VAENAAA-------QLEKYNEQLELSSRYKSEFLANMSHELRTPLNSMLILSQLLTENRN 541 AE A +LE+ +L SS+YKSEFLANMSHELRTPLNS+L+LS++L EN + Sbjct: 467 EAEQKTADLQVTKLELEEKASELLRSSKYKSEFLANMSHELRTPLNSILLLSEMLKENHD 526 Query: 542 DSLTEEEQGYAEVIHSSGSELLGMINDILDLSKVEAGKMTVERDPVNLTELPSILYGYF 600 + L+++E A VIHSSG +LL +INDILDLSKVEAGK+ V + N++++ + + F Sbjct: 527 NHLSDDEIELATVIHSSGKDLLTLINDILDLSKVEAGKLDVIFEATNISDMAASMQQNF 585 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.132 0.366 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,166,675,787 Number of extensions: 124158728 Number of successful extensions: 447108 Number of sequences better than 1.0e-05: 7242 Number of HSP's gapped: 447454 Number of HSP's successfully gapped: 7301 Length of query: 615 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 473 Effective length of database: 1,722,912,073 Effective search space: 814937410529 Effective search space used: 814937410529 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)