BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0518.0001.p (182 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KAX7.1 B3KAX7_9BACI Adenosylcobinamide kinase EC=2.7.1.156 177 5e-43 B1DLT7.1 B1DLT7_9BACL Adenosylcobinamide-phosphate guanylyltrans... 166 8e-40 C0ZGK3.1 C0ZGK3_BREBN Probable adenosylcobinamide kinase/adenosy... 154 4e-36 Q3AE12.1 Q3AE12_CARHZ Cobalamin biosynthesis protein CobP 135 1e-30 B3E974.1 B3E974_GEOLS Adenosylcobinamide kinase EC=2.7.1.156 132 1e-29 >B3KAX7.1 B3KAX7_9BACI Adenosylcobinamide kinase EC=2.7.1.156 Length = 192 Score = 177 bits (448), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 95/190 (50%), Positives = 119/190 (62%), Gaps = 12/190 (6%) Query: 2 SILVTGGARSGKSGFAEQLVFSLADQAVYVATGQAFDEEMKARIALHRKLREESGGAWXX 61 S+LVTGGARSGKS FAE+L AD Y+AT QA+D+EM+ RI +H+ R++S W Sbjct: 6 SVLVTGGARSGKSSFAEKLCMKRADSGTYIATAQAYDDEMRERIRIHQDRRQDSAYGWQT 65 Query: 62 XXXXXXXXXXXDRL----SGGKAVLVDCLTLWLSNVLLAVEDQ-----EDRQXXXXXXXX 112 + L S AV+VDCLTLWL+NVLL E + E+R Sbjct: 66 VEEPVALPELLETLGQSASDAPAVVVDCLTLWLTNVLLQAEPEGTAVMEER---LGLQID 122 Query: 113 XXXXXXASFRGTLVLVTNEVGDGIVPEYPLGRLYRDLAGRMNALLARQCGQVFLVTAGIP 172 + G ++LVTNEVG GIVPEYPLGR+YRD AG MN LA+ C +VFLVTAGIP Sbjct: 123 RLARAVQVYPGMVILVTNEVGSGIVPEYPLGRIYRDWAGIMNQRLAQVCDEVFLVTAGIP 182 Query: 173 VELKSREYRL 182 +E+KSREYR+ Sbjct: 183 MEIKSREYRI 192 >B1DLT7.1 B1DLT7_9BACL Adenosylcobinamide-phosphate guanylyltransferase EC=2.7.7.62 Length = 200 Score = 166 bits (420), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 93/196 (47%), Positives = 121/196 (61%), Gaps = 15/196 (7%) Query: 1 MSILVTGGARSGKSGFAEQLVFSLADQAVYVATGQAFDEEMKARIALHRKLREESGGAWX 60 M++LVTGGARSGKS FAE+L L +Q VY+AT + +DEEM RIALH++ RE+SG W Sbjct: 1 MAMLVTGGARSGKSSFAEKLAARLGEQGVYIATSRIWDEEMAERIALHQQNREQSGFRWT 60 Query: 61 XXXXXXXXXXXXDRLSG---------GKA--VLVDCLTLWLSNVLLAVEDQEDRQXXXXX 109 +L+ GK +LVDCLTLWL+NVL+ E++E + Sbjct: 61 TIEEPVGLSGRLRQLAKEAYELELMEGKPPVILVDCLTLWLTNVLMEAEEREKSESMEKD 120 Query: 110 XXXXXXXXXAS----FRGTLVLVTNEVGDGIVPEYPLGRLYRDLAGRMNALLARQCGQVF 165 A+ + L+LVTNEVGDGIVP YPLGR +RD AGR+N +A +VF Sbjct: 121 WLSEQVNELAAAVQEYNYPLILVTNEVGDGIVPAYPLGRRFRDEAGRLNQRMAALSDKVF 180 Query: 166 LVTAGIPVELKSREYR 181 LVTAGIPVELK+ ++R Sbjct: 181 LVTAGIPVELKAMQFR 196 >C0ZGK3.1 C0ZGK3_BREBN Probable adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase EC=2.7.1.156 EC=2.7.7.62 Length = 188 Score = 154 bits (388), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 86/190 (45%), Positives = 108/190 (56%), Gaps = 10/190 (5%) Query: 1 MSILVTGGARSGKSGFAEQLVFSLADQAVYVATGQAFDEEMKARIALHRKLREESGGAWX 60 M +L+TGGARSGKS FAE+ L VY+AT DEEM+ RI HR R +S W Sbjct: 1 MIVLITGGARSGKSTFAEKYAAHLGSSGVYIATAPITDEEMEERILHHRDRRLQSNFPWQ 60 Query: 61 XXXXXXXXXXXXDRLSGGK-------AVLVDCLTLWLSNVLLAVEDQEDRQXX-XXXXXX 112 +L K +L+DCL LWLSN LL DQE++ Sbjct: 61 TIEEPYALTEWLTKLGAQKDIQEQQTVILIDCLILWLSNWLL--HDQEEQSFEGVLQQVD 118 Query: 113 XXXXXXASFRGTLVLVTNEVGDGIVPEYPLGRLYRDLAGRMNALLARQCGQVFLVTAGIP 172 + GT++LVTNEVGDG+VP++PLGR++RDLAG MN +A QVFLVTAGIP Sbjct: 119 VLVNKLKDYHGTVLLVTNEVGDGLVPQHPLGRMFRDLAGLMNQRVAAVADQVFLVTAGIP 178 Query: 173 VELKSREYRL 182 VELK + +R Sbjct: 179 VELKGQAFRF 188 >Q3AE12.1 Q3AE12_CARHZ Cobalamin biosynthesis protein CobP Length = 168 Score = 135 bits (341), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 78/178 (43%), Positives = 102/178 (57%), Gaps = 15/178 (8%) Query: 1 MSILVTGGARSGKSGFAEQLVFSLADQAVYVATGQAFDEEMKARIALHRKLREESGGAWX 60 M +L+TGG RSGKS FAE+L S ++ VYVAT A DEEM+ RIA H+ R + W Sbjct: 1 MKVLITGGVRSGKSSFAEKLATSFGEKVVYVATATAGDEEMRERIAKHQSRRPPN---WV 57 Query: 61 XXXXXXXXXXXXDRL--SGGKAVLVDCLTLWLSNVLLAVEDQEDRQXXXXXXXXXXXXXX 118 D L + G AVLVDCLTLW++N+LL ED + Sbjct: 58 TVEEPVNLR---DVLLTARGDAVLVDCLTLWVTNLLLKEEDVVGK-------AYEVVEIF 107 Query: 119 ASFRGTLVLVTNEVGDGIVPEYPLGRLYRDLAGRMNALLARQCGQVFLVTAGIPVELK 176 L+ VTNEVG GIVP+ PL R +RD+AG +N + A+ C +V+L AGIPV++K Sbjct: 108 PRITVPLIFVTNEVGSGIVPDNPLARKFRDVAGLVNQVFAKYCDEVYLTVAGIPVKIK 165 >B3E974.1 B3E974_GEOLS Adenosylcobinamide kinase EC=2.7.1.156 Length = 177 Score = 132 bits (333), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 79/179 (44%), Positives = 102/179 (56%), Gaps = 9/179 (5%) Query: 2 SILVTGGARSGKSGFAEQLVFSLADQAVYVATGQAFDEEMKARIALHRKLREESGGAWXX 61 + L+TGGARSGKS FAE+L S Y+AT Q D+EM RI H+ R G AW Sbjct: 4 NTLITGGARSGKSRFAEELTRSFGPSLCYLATAQPLDDEMGERIHRHQLRR---GTAWET 60 Query: 62 XXXXXXXXXXXDRLSG-GKAVLVDCLTLWLSNVLLAVEDQEDRQXXXXXXXXXXXXXXAS 120 R+ G A+L+DC+TLWLSN+LL+ + E+ + Sbjct: 61 LEEPLMIPQTLARIDGIYSAILLDCVTLWLSNLLLSCD--ENDPGCEEQVLSHVHRLAGT 118 Query: 121 FRG---TLVLVTNEVGDGIVPEYPLGRLYRDLAGRMNALLARQCGQVFLVTAGIPVELK 176 RG +VLVTNEVG GIVPE LGRLYRD+AG+ N LLA C V++ +GIP++LK Sbjct: 119 LRGMSTPVVLVTNEVGQGIVPENRLGRLYRDIAGQANQLLAAGCDAVYVTISGIPLKLK 177 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.395 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 872,992,985 Number of extensions: 26735959 Number of successful extensions: 55513 Number of sequences better than 1.0e-05: 698 Number of HSP's gapped: 54063 Number of HSP's successfully gapped: 709 Length of query: 182 Length of database: 3,060,696,203 Length adjustment: 127 Effective length of query: 55 Effective length of database: 1,864,227,298 Effective search space: 102532501390 Effective search space used: 102532501390 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)