BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0515.0003.p (471 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K7D6.1 B3K7D6_9BACI Argininosuccinate lyase 847 0.0 B1DE84.1 B1DE84_9BACL Argininosuccinate lyase 808 0.0 C0Z6R9.1 C0Z6R9_BREBN Argininosuccinate lyase EC=4.3.2.1 692 0.0 C1PF82.1 C1PF82_BACCO Argininosuccinate lyase 671 0.0 Q8ELT9.1 ARLY_OCEIH Argininosuccinate lyase EC=4.3.2.1 670 0.0 >B3K7D6.1 B3K7D6_9BACI Argininosuccinate lyase Length = 471 Score = 847 bits (2187), Expect = 0.0, Method: Compositional matrix adjust. Identities = 403/464 (86%), Positives = 431/464 (92%) Query: 1 VSKLWGGRFTKGTNKLVEEYTASIGFDKVLAEEDVQGSLAHVTMLGKCGILPQEDVETIK 60 +SKLWGGRFTK TN LVEEYTASIGFDK LAEED+QGSLAHV+MLGKCGI+P EDVETIK Sbjct: 1 MSKLWGGRFTKQTNALVEEYTASIGFDKQLAEEDIQGSLAHVSMLGKCGIVPAEDVETIK 60 Query: 61 NGLNKVLGKVRAGEIVFSVADEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLY 120 GL KVL ++R G I FSV+DEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLY Sbjct: 61 AGLGKVLERIREGSIEFSVSDEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLY 120 Query: 121 LRNRVVELVALLHELQEALIGQAKDNVDTIVPGYTHLQRAQPILFAHHLLAYVSMFRRDA 180 LRNRVV L +LHELQ ALIGQAKDN+DTI+PGYTHLQRAQPILFAHHL+AYVSMF+RD Sbjct: 121 LRNRVVALTGMLHELQTALIGQAKDNLDTIIPGYTHLQRAQPILFAHHLMAYVSMFQRDI 180 Query: 181 ERLTDSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFIVEFLA 240 +RL DSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFI+EFL+ Sbjct: 181 DRLIDSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFILEFLS 240 Query: 241 NAALVMTHLSRLSEELVLWSSTEFSFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY 300 +A+++M HLSRLSEELVLWSSTEF+FVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY Sbjct: 241 DASIIMMHLSRLSEELVLWSSTEFNFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY 300 Query: 301 GNLIGLLTVLKSLPLAYNKDMQEDKEGMFDTVATLTGALQLFAPMISTMKVNKGRMREAV 360 GNL+GLLTVLKSLPLAYNKDMQEDKEGMFDTVATL GALQLFAPMI+TMKVNKGRMREAV Sbjct: 301 GNLMGLLTVLKSLPLAYNKDMQEDKEGMFDTVATLEGALQLFAPMIATMKVNKGRMREAV 360 Query: 361 NTDFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCINEGKFLLDLTLEEFKQFSPLFDEQ 420 NTDFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCI K+LLDLTL+EFKQFS LFD+ Sbjct: 361 NTDFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCIQNNKYLLDLTLDEFKQFSELFDDS 420 Query: 421 IYAVLQPEAVVNARNVYGGTATVQVKAAIERAEAALNEASEWIA 464 IY VLQPEAVVNARNVYGGTAT QVKAAI+R+ L EW+ Sbjct: 421 IYGVLQPEAVVNARNVYGGTATEQVKAAIDRSVQTLQVTEEWLG 464 >B1DE84.1 B1DE84_9BACL Argininosuccinate lyase Length = 471 Score = 808 bits (2088), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/471 (80%), Positives = 425/471 (90%) Query: 1 VSKLWGGRFTKGTNKLVEEYTASIGFDKVLAEEDVQGSLAHVTMLGKCGILPQEDVETIK 60 +SKLWGGRFTK T++LVEEYTASI FDK LAEED+QGSLAHVTMLGK GILP +DVE IK Sbjct: 1 MSKLWGGRFTKKTDQLVEEYTASIMFDKELAEEDIQGSLAHVTMLGKQGILPADDVEAIK 60 Query: 61 NGLNKVLGKVRAGEIVFSVADEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLY 120 +GL++VL +++ +I FS++DEDIHMNIEK LI+++GPVGGKLHTGRSRNDQVATDMHLY Sbjct: 61 DGLHRVLQRIKRNDIEFSISDEDIHMNIEKTLIDDVGPVGGKLHTGRSRNDQVATDMHLY 120 Query: 121 LRNRVVELVALLHELQEALIGQAKDNVDTIVPGYTHLQRAQPILFAHHLLAYVSMFRRDA 180 LR RVVE V +LH+LQ ALI QAK N+DTIVPGYTHLQRAQPILFAHHL+AYVSMF RD Sbjct: 121 LRKRVVEFVDMLHKLQSALIEQAKANIDTIVPGYTHLQRAQPILFAHHLMAYVSMFGRDL 180 Query: 181 ERLTDSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFIVEFLA 240 ERL DSYKRIN+LPLGAGALAGTTFPIDRHFVA QL FD VYENSLDAVSDRDFI+EFL+ Sbjct: 181 ERLQDSYKRINMLPLGAGALAGTTFPIDRHFVASQLKFDRVYENSLDAVSDRDFILEFLS 240 Query: 241 NAALVMTHLSRLSEELVLWSSTEFSFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY 300 +A+++M HLSRLSEEL+LWSSTEF FVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY Sbjct: 241 HASIIMMHLSRLSEELILWSSTEFRFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY 300 Query: 301 GNLIGLLTVLKSLPLAYNKDMQEDKEGMFDTVATLTGALQLFAPMISTMKVNKGRMREAV 360 GNL+GLLTVLKSLPLAYNKDMQEDKEGMFDTV T+ GALQLFAPMI+TMKVNK +MR+AV Sbjct: 301 GNLVGLLTVLKSLPLAYNKDMQEDKEGMFDTVKTMQGALQLFAPMIATMKVNKEQMRQAV 360 Query: 361 NTDFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCINEGKFLLDLTLEEFKQFSPLFDEQ 420 N DFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCI + K+LLDLTLEEFKQFS LFD++ Sbjct: 361 NQDFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCIEQNKYLLDLTLEEFKQFSQLFDDR 420 Query: 421 IYAVLQPEAVVNARNVYGGTATVQVKAAIERAEAALNEASEWIAQHVNTIR 471 IY VLQPE VVNARNVYGGTA VQV+AAI RAE L + + W+ ++ R Sbjct: 421 IYNVLQPEQVVNARNVYGGTAKVQVEAAIARAEQVLEQTAAWVTEYAEKSR 471 >C0Z6R9.1 C0Z6R9_BREBN Argininosuccinate lyase EC=4.3.2.1 Length = 481 Score = 692 bits (1787), Expect = 0.0, Method: Compositional matrix adjust. Identities = 330/461 (71%), Positives = 379/461 (82%) Query: 3 KLWGGRFTKGTNKLVEEYTASIGFDKVLAEEDVQGSLAHVTMLGKCGILPQEDVETIKNG 62 KLWGGRFTK TN+LVEEYTASI FD+ + +D+ GSLAHV MLGKCGILP E+V I G Sbjct: 2 KLWGGRFTKPTNQLVEEYTASISFDQKMWRQDIVGSLAHVAMLGKCGILPMEEVRQIIAG 61 Query: 63 LNKVLGKVRAGEIVFSVADEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLYLR 122 L KV K+ G+ F VA ED+HMNIEK LIEEIGPVGGKLHTGRSRNDQVA DMHLYLR Sbjct: 62 LKKVKEKIERGQAEFLVAHEDVHMNIEKMLIEEIGPVGGKLHTGRSRNDQVALDMHLYLR 121 Query: 123 NRVVELVALLHELQEALIGQAKDNVDTIVPGYTHLQRAQPILFAHHLLAYVSMFRRDAER 182 +++E++ L LQEAL+ QA ++DT++PGYTHLQRAQP+LF +HL+AYVSM +RD ER Sbjct: 122 EKLMEIIQLAMYLQEALLEQAGQHLDTVMPGYTHLQRAQPVLFGYHLMAYVSMLQRDIER 181 Query: 183 LTDSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFIVEFLANA 242 +T+++KR+NVLPLGAGALAGTTFPIDR FVAE L FDG+Y+NS+DAVSDRDFIVEFLA+A Sbjct: 182 MTETWKRVNVLPLGAGALAGTTFPIDRTFVAELLQFDGIYQNSMDAVSDRDFIVEFLADA 241 Query: 243 ALVMTHLSRLSEELVLWSSTEFSFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVYGN 302 +LVMTHLSRL EELV+WSS EFSFVELDDAFCTGSSIMPQKKNPDV ELVRGKTGRVYGN Sbjct: 242 SLVMTHLSRLCEELVIWSSQEFSFVELDDAFCTGSSIMPQKKNPDVAELVRGKTGRVYGN 301 Query: 303 LIGLLTVLKSLPLAYNKDMQEDKEGMFDTVATLTGALQLFAPMISTMKVNKGRMREAVNT 362 L GLLTVLK LPLAYNKDMQEDKEGMFDTVAT+ GAL L PMI TM+V RMR+AV Sbjct: 302 LFGLLTVLKGLPLAYNKDMQEDKEGMFDTVATIHGALALLTPMIKTMQVKTDRMRQAVTN 361 Query: 363 DFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCINEGKFLLDLTLEEFKQFSPLFDEQIY 422 DFSNATD+AD+LV K +PFRQAHEV+G+TVLYCI + K+LLDLTLEEF+ FS +Y Sbjct: 362 DFSNATDLADYLVRKDMPFRQAHEVVGRTVLYCIEQQKYLLDLTLEEFQSFSEAIGADVY 421 Query: 423 AVLQPEAVVNARNVYGGTATVQVKAAIERAEAALNEASEWI 463 L E VVNARNV GGTA QV+ I+ L E W+ Sbjct: 422 EALAVETVVNARNVLGGTARNQVEVQIDWYRKQLVETHAWV 462 >C1PF82.1 C1PF82_BACCO Argininosuccinate lyase Length = 462 Score = 671 bits (1730), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/458 (69%), Positives = 377/458 (82%) Query: 1 VSKLWGGRFTKGTNKLVEEYTASIGFDKVLAEEDVQGSLAHVTMLGKCGILPQEDVETIK 60 +SKLWGGRFTK TN+LVE YTASIG+D+ LA ED++GSLAHV MLG+CGILP+ DVE IK Sbjct: 3 LSKLWGGRFTKETNQLVETYTASIGYDQRLAFEDIEGSLAHVQMLGECGILPENDVEQIK 62 Query: 61 NGLNKVLGKVRAGEIVFSVADEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLY 120 GL K+ K++ GE F+V +EDIHMNIEK L++EIGP GGKLHTGRSRNDQVATDMHLY Sbjct: 63 AGLRKIAEKIKNGEAAFTVENEDIHMNIEKMLMDEIGPAGGKLHTGRSRNDQVATDMHLY 122 Query: 121 LRNRVVELVALLHELQEALIGQAKDNVDTIVPGYTHLQRAQPILFAHHLLAYVSMFRRDA 180 +R E++ L+ +QEA++ +AK+N +T++PGYTHLQRAQP+LFAHHLLAY M RD Sbjct: 123 VRKTTKEMIRLIALVQEAIVTKAKENKETMMPGYTHLQRAQPVLFAHHLLAYFWMLERDK 182 Query: 181 ERLTDSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFIVEFLA 240 ER +DS KR + LPLGAGALAGTTFPIDR E LGF +Y NSLDAVSDRDF++EFLA Sbjct: 183 ERFSDSLKRTDWLPLGAGALAGTTFPIDRERTRELLGFSRIYPNSLDAVSDRDFVLEFLA 242 Query: 241 NAALVMTHLSRLSEELVLWSSTEFSFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVY 300 NAA++MTH+SRLSEELVLWSS EF F+ELDD+FCTGSSIMPQKKNPDVPEL+RGKTGRV+ Sbjct: 243 NAAILMTHISRLSEELVLWSSQEFQFIELDDSFCTGSSIMPQKKNPDVPELLRGKTGRVF 302 Query: 301 GNLIGLLTVLKSLPLAYNKDMQEDKEGMFDTVATLTGALQLFAPMISTMKVNKGRMREAV 360 GNLIGLLTVLK LPLAYNKDMQEDKEG+FDT TL GAL+L APMI TMKVN+ +M AV Sbjct: 303 GNLIGLLTVLKGLPLAYNKDMQEDKEGIFDTADTLQGALKLLAPMIETMKVNREKMFRAV 362 Query: 361 NTDFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCINEGKFLLDLTLEEFKQFSPLFDEQ 420 + D++NATDIAD+L KGLPFR+AH VIG+ VLY I GK+LLDLTL+E++ FSPLF+ Sbjct: 363 SNDYANATDIADYLAKKGLPFREAHAVIGQIVLYGIQHGKYLLDLTLDEYQSFSPLFEAD 422 Query: 421 IYAVLQPEAVVNARNVYGGTATVQVKAAIERAEAALNE 458 I+ VL+P VV RN GGT QV A ++ AE L + Sbjct: 423 IFEVLKPVHVVKMRNSAGGTGHAQVAAQLQMAEKQLRK 460 >Q8ELT9.1 ARLY_OCEIH Argininosuccinate lyase EC=4.3.2.1 Length = 459 Score = 670 bits (1729), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/457 (69%), Positives = 375/457 (82%) Query: 3 KLWGGRFTKGTNKLVEEYTASIGFDKVLAEEDVQGSLAHVTMLGKCGILPQEDVETIKNG 62 KLWGGRFTK TN+LV+EY +SI FDK LA D++GSLAHV ML KC I+P ED + I G Sbjct: 2 KLWGGRFTKPTNELVDEYASSIQFDKKLAAYDIEGSLAHVAMLKKCEIIPAEDADKIAEG 61 Query: 63 LNKVLGKVRAGEIVFSVADEDIHMNIEKNLIEEIGPVGGKLHTGRSRNDQVATDMHLYLR 122 L VL K+ AGE S EDIHMN+EK LI+E+GPVGG+LHTGRSRNDQVA DM LYLR Sbjct: 62 LKIVLSKIEAGEAELSNEHEDIHMNVEKLLIDEVGPVGGRLHTGRSRNDQVALDMRLYLR 121 Query: 123 NRVVELVALLHELQEALIGQAKDNVDTIVPGYTHLQRAQPILFAHHLLAYVSMFRRDAER 182 + + EL LL +Q++LI QAK N+DT++PGYTHLQRAQP+LFAHH++AYV MF+RD ER Sbjct: 122 DVIAELSDLLKAVQQSLITQAKANMDTVMPGYTHLQRAQPVLFAHHMMAYVFMFQRDVER 181 Query: 183 LTDSYKRINVLPLGAGALAGTTFPIDRHFVAEQLGFDGVYENSLDAVSDRDFIVEFLANA 242 DS KR+N PLGAGALAGTTFPIDRHFVAEQLGFDG+ ENSLDAVSDRDF+VEFL+N+ Sbjct: 182 FQDSLKRVNKSPLGAGALAGTTFPIDRHFVAEQLGFDGICENSLDAVSDRDFVVEFLSNS 241 Query: 243 ALVMTHLSRLSEELVLWSSTEFSFVELDDAFCTGSSIMPQKKNPDVPELVRGKTGRVYGN 302 ALV THLSRL EELV WSS EF+FVELDD+F TGSS+MPQKKNPDV ELVRGKTGRVYG+ Sbjct: 242 ALVSTHLSRLCEELVQWSSAEFNFVELDDSFTTGSSMMPQKKNPDVAELVRGKTGRVYGH 301 Query: 303 LIGLLTVLKSLPLAYNKDMQEDKEGMFDTVATLTGALQLFAPMISTMKVNKGRMREAVNT 362 L+G+LT LK LPLAYNKDMQEDKEGMFD TL GALQLFAPM+ +MKVNK M +AV+ Sbjct: 302 LMGMLTTLKGLPLAYNKDMQEDKEGMFDAHETLKGALQLFAPMMESMKVNKESMYKAVSN 361 Query: 363 DFSNATDIADFLVGKGLPFRQAHEVIGKTVLYCINEGKFLLDLTLEEFKQFSPLFDEQIY 422 D+SNATD+AD+LV KG+ FR++H V+G+ VL+CI + K+LLDLTL+EFKQ+S + DE I+ Sbjct: 362 DYSNATDLADYLVNKGMTFRESHAVVGEAVLHCIEQNKYLLDLTLKEFKQYSEVIDEDIF 421 Query: 423 AVLQPEAVVNARNVYGGTATVQVKAAIERAEAALNEA 459 VL+PEAVVNAR+V GGTA V I +AE L A Sbjct: 422 DVLKPEAVVNARSVEGGTAKESVLQQIAKAEKLLESA 458 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,709,396,466 Number of extensions: 113562634 Number of successful extensions: 276557 Number of sequences better than 1.0e-05: 3533 Number of HSP's gapped: 274578 Number of HSP's successfully gapped: 3538 Length of query: 471 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 332 Effective length of database: 1,751,175,118 Effective search space: 581390139176 Effective search space used: 581390139176 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 133 (55.8 bits)