BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0061.p (475 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KIL8.1 B3KIL8_9BACI Nicotinate phosphoribosyltransferase EC=2.... 747 0.0 B1D9P2.1 B1D9P2_9BACL Nicotinate phosphoribosyltransferase EC=2.... 655 0.0 C0Z4V1.1 C0Z4V1_BREBN Putative nicotinate phosphoribosyltransfer... 647 0.0 A5D1R4.1 A5D1R4_PELTS Nicotinate phosphoribosyltransferase EC=2.... 630 e-178 A4IP15.1 A4IP15_GEOTN Nicotinate phosphoribosyltransferase EC=2.... 515 e-144 >B3KIL8.1 B3KIL8_9BACI Nicotinate phosphoribosyltransferase EC=2.4.2.11 Length = 484 Score = 747 bits (1928), Expect = 0.0, Method: Compositional matrix adjust. Identities = 359/464 (77%), Positives = 408/464 (87%), Gaps = 2/464 (0%) Query: 1 MMYAHWVNGSHKRRAVFEAYFRKLPFGNGFAVFAGLERITQYISELRFTEEDIRYLSEQE 60 MMYAHW+NGSH+ RAVFE YFRKLPFGNG+AVFAGLERI YI LRF++EDI YL++QE Sbjct: 17 MMYAHWINGSHRTRAVFEGYFRKLPFGNGYAVFAGLERIVHYIESLRFSDEDIAYLAKQE 76 Query: 61 ENYAPAFLEELLQFHFQGSIYSMKEGALVFPDEPLVRVEGTIMEAQLVETAILNFMNYQT 120 E Y P FLEEL +F FQG+I+SMKEGALVFP+EPL+RVEGTI E QLVETA+LNFMN+QT Sbjct: 77 EKYKPEFLEELRRFRFQGNIHSMKEGALVFPNEPLIRVEGTIFETQLVETALLNFMNFQT 136 Query: 121 LIATKASRIKQVAPKDTLLEFGTRRAQEADAAVWGARAAYISGFHATSNMLAGKKFGIPT 180 LIATKASRI+QVA DTLLEFGTRRAQEADAAVWGARAAY++GFHATSNMLAG+KFGIPT Sbjct: 137 LIATKASRIRQVAGGDTLLEFGTRRAQEADAAVWGARAAYLAGFHATSNMLAGEKFGIPT 196 Query: 181 KGTHAHSWVQSFASEQEAFDAYAKVMPDGVTLLVDTFDTLRSGVPHAINTAKMLEAAGKR 240 KGTHAHSWVQ+F SEQEAFD +A+VMPD VTLLVDTFDTL+SG+PHAI TAK LEA GKR Sbjct: 197 KGTHAHSWVQTFRSEQEAFDIFAEVMPDQVTLLVDTFDTLKSGIPHAIATAKKLEAQGKR 256 Query: 241 MNAIRLDSGDLAYLSIQARKMLDEAGLDYVKIVASNDLDENTIMNLKSQGAAIDTWGVGT 300 MNAIRLDSGDLAYLSIQARKMLDEAGL YV IVASNDLDE TI++LK+QGA +DTWGVGT Sbjct: 257 MNAIRLDSGDLAYLSIQARKMLDEAGLHYVGIVASNDLDEGTILDLKAQGAKVDTWGVGT 316 Query: 301 QLITASDQPSLGGVYKLVEIESPNGEMVPTIKISSNPEKVSTPGKKEVFRIVGP-KGKAL 359 QLITA+DQP+LGGVYKLVE E +G+MVPTIKIS NPEKVSTPGKK+V+RI+ GKA+ Sbjct: 317 QLITAADQPALGGVYKLVEREV-DGKMVPTIKISGNPEKVSTPGKKDVYRIISKGSGKAI 375 Query: 360 ADYISFPGEQEPRSGRRLKLFNPLHPYLQKYVEKYEAVSMLEPIFVNGFQVYKLPVLDEI 419 ADYI FP E+ P +LKLFNPLHPY++K V+ +EAVSMLEPIF +G VY+LP L+EI Sbjct: 376 ADYICFPEEEMPPESGKLKLFNPLHPYMRKNVKNFEAVSMLEPIFQHGELVYELPELEEI 435 Query: 420 RRYHQEQIDLFWPEYLRKLNPEVYRVNLSELVWTRKQQLIAEHM 463 R YH Q+ FWPEYLRKLNPE+YRVNLSE VW KQ+++AE M Sbjct: 436 RSYHDAQLGQFWPEYLRKLNPEIYRVNLSEEVWEVKQRMMAEFM 479 >B1D9P2.1 B1D9P2_9BACL Nicotinate phosphoribosyltransferase EC=2.4.2.11 Length = 481 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 317/463 (68%), Positives = 376/463 (81%), Gaps = 2/463 (0%) Query: 1 MMYAHWVNGSHKRRAVFEAYFRKLPFGNGFAVFAGLERITQYISELRFTEEDIRYLSEQE 60 MMYAHW+NG+ AVFEA+FRKLPFGNG+AVFAGLERI +I L+F EE++ YL++QE Sbjct: 18 MMYAHWINGTDGEGAVFEAFFRKLPFGNGYAVFAGLERIVDFIRHLKFGEEELAYLAKQE 77 Query: 61 ENYAPAFLEELLQFHFQGSIYSMKEGALVFPDEPLVRVEGTIMEAQLVETAILNFMNYQT 120 ENY P FLE L QF F+G++++++EG+LVFP+EP+VRVEGTI E QLVETA+LNFMNYQT Sbjct: 78 ENYDPGFLEVLRQFRFKGTVHAVEEGSLVFPNEPIVRVEGTIFETQLVETALLNFMNYQT 137 Query: 121 LIATKASRIKQVAPKDTLLEFGTRRAQEADAAVWGARAAYISGFHATSNMLAGKKFGIPT 180 LIATKASRIKQVA D LLEFGTRRAQEADAAVWGARAAYI+GFHATSNM AG FGIPT Sbjct: 138 LIATKASRIKQVASGDILLEFGTRRAQEADAAVWGARAAYIAGFHATSNMHAGMMFGIPT 197 Query: 181 KGTHAHSWVQSFASEQEAFDAYAKVMPDGVTLLVDTFDTLRSGVPHAINTAKMLEAAGKR 240 KGTHAHSWVQ SE+EAF AYAK +PDGVTLLVDT+DTLRSGVP+AI TA+ LE+ GKR Sbjct: 198 KGTHAHSWVQGHESEEEAFLAYAKALPDGVTLLVDTYDTLRSGVPNAIKTARYLESIGKR 257 Query: 241 MNAIRLDSGDLAYLSIQARKMLDEAGLDYVKIVASNDLDENTIMNLKSQGAAIDTWGVGT 300 + IRLDSGDLAYLS +ARKMLD AGL KIVASNDLDE I NLK+QGA IDTWGVGT Sbjct: 258 LGGIRLDSGDLAYLSKEARKMLDAAGLQDAKIVASNDLDETLIFNLKAQGAKIDTWGVGT 317 Query: 301 QLITASDQPSLGGVYKLVEIESPNGEMVPTIKISSNPEKVSTPGKKEVFRIVGPK-GKAL 359 QLITA+DQPSLGGVYKL +G+ +P IKIS NPEKVS PGKK+V+RI+ G A Sbjct: 318 QLITAADQPSLGGVYKLTA-RKRDGQYIPVIKISGNPEKVSAPGKKDVYRIMNKSTGLAE 376 Query: 360 ADYISFPGEQEPRSGRRLKLFNPLHPYLQKYVEKYEAVSMLEPIFVNGFQVYKLPVLDEI 419 ADY++ E + +G R+KLF+P+HPY+ +++ YEAV +L+PI V G VYKLP+L+EI Sbjct: 377 ADYMTLHDETDILNGERIKLFDPVHPYIHRFISDYEAVPLLKPIVVEGEIVYKLPLLEEI 436 Query: 420 RRYHQEQIDLFWPEYLRKLNPEVYRVNLSELVWTRKQQLIAEH 462 R YH+ Q+ +F PE LRKLNP++Y V+LSE W K LI H Sbjct: 437 RSYHEHQLSIFRPEILRKLNPDLYPVHLSEQAWQLKTDLIKAH 479 >C0Z4V1.1 C0Z4V1_BREBN Putative nicotinate phosphoribosyltransferase EC=2.4.2.11 Length = 482 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 311/464 (67%), Positives = 381/464 (82%), Gaps = 1/464 (0%) Query: 1 MMYAHWVNGSHKRRAVFEAYFRKLPFGNGFAVFAGLERITQYISELRFTEEDIRYLSEQE 60 MMYAHWVNG+H ++ VFEA+FRKLPFGNG+AV AGLERI YI LRF E D++YLSEQE Sbjct: 17 MMYAHWVNGTHNQKVVFEAFFRKLPFGNGYAVSAGLERIVSYIKNLRFEESDLKYLSEQE 76 Query: 61 ENYAPAFLEELLQFHFQGSIYSMKEGALVFPDEPLVRVEGTIMEAQLVETAILNFMNYQT 120 ENY P FLEEL Q F+GS+YS+KEG +VFP+EPL+RVEG +MEAQLVETA+LN+MNYQT Sbjct: 77 ENYDPKFLEELRQLRFKGSLYSVKEGTVVFPNEPLIRVEGRVMEAQLVETALLNYMNYQT 136 Query: 121 LIATKASRIKQVAPKDTLLEFGTRRAQEADAAVWGARAAYISGFHATSNMLAGKKFGIPT 180 LIATKASRIK VA D L+EFGTRRAQEADAA+WG RAAY++GF ATSNMLAGK FGIPT Sbjct: 137 LIATKASRIKNVAGNDVLMEFGTRRAQEADAALWGTRAAYLAGFDATSNMLAGKMFGIPT 196 Query: 181 KGTHAHSWVQSFASEQEAFDAYAKVMPDGVTLLVDTFDTLRSGVPHAINTAKMLEAAGKR 240 KGTHAHSWVQSF SE+EAF+ +A +P VTLLVDT+DTL+SGVP+AI K LE GK+ Sbjct: 197 KGTHAHSWVQSFESEEEAFERFAAALPGQVTLLVDTYDTLKSGVPNAIKVGKRLEKQGKK 256 Query: 241 MNAIRLDSGDLAYLSIQARKMLDEAGLDYVKIVASNDLDENTIMNLKSQGAAIDTWGVGT 300 + A+RLDSGDL YLS + R+MLD+AG+ V+IVASNDLDE+TIMNLK QGA +++WGVGT Sbjct: 257 LTAVRLDSGDLTYLSCKTREMLDKAGMTDVQIVASNDLDEHTIMNLKVQGARVNSWGVGT 316 Query: 301 QLITASDQPSLGGVYKLVEIESPNGEMVPTIKISSNPEKVSTPGKKEVFRIVGPK-GKAL 359 QLITA+DQP+LGGVYKLV E +GE PTIKIS NPEKV+TPG K+++R++ P+ GKA+ Sbjct: 317 QLITAADQPTLGGVYKLVAREGADGEYQPTIKISGNPEKVTTPGIKDMYRLIDPETGKAI 376 Query: 360 ADYISFPGEQEPRSGRRLKLFNPLHPYLQKYVEKYEAVSMLEPIFVNGFQVYKLPVLDEI 419 ADY+ FP E G L LF+P H YL K++E Y+A S+L P+FV+G +Y+LP L EI Sbjct: 377 ADYMCFPHETTVEKGAPLHLFHPSHTYLSKHLENYQAKSLLVPVFVDGELIYELPTLQEI 436 Query: 420 RRYHQEQIDLFWPEYLRKLNPEVYRVNLSELVWTRKQQLIAEHM 463 R YH+EQ+ LFWPEYLR LNPE YR+++SE +W K +L+ ++ Sbjct: 437 RNYHREQLKLFWPEYLRMLNPEHYRLHISEEMWETKTKLMKAYL 480 >A5D1R4.1 A5D1R4_PELTS Nicotinate phosphoribosyltransferase EC=2.4.2.11 Length = 480 Score = 630 bits (1624), Expect = e-178, Method: Compositional matrix adjust. Identities = 298/463 (64%), Positives = 369/463 (79%), Gaps = 3/463 (0%) Query: 1 MMYAHWVNGSHKRRAVFEAYFRKLPFGNGFAVFAGLERITQYISELRFTEEDIRYLSEQE 60 M+Y +W G H +R VFEA+FRKLPFGNGFAVFAGLERI YI+ LRFTEEDI +L++QE Sbjct: 17 MIYGYWKKGMHNKRCVFEAFFRKLPFGNGFAVFAGLERIVNYINNLRFTEEDIAFLAQQE 76 Query: 61 ENYAPAFLEELLQFHFQGSIYSMKEGALVFPDEPLVRVEGTIMEAQLVETAILNFMNYQT 120 ENY P F EEL +F F G++ +++EG ++FP+EPL++VEG + EAQL+ETAILNFMNYQT Sbjct: 77 ENYDPDFFEELRKFRFTGNLRAVREGTVIFPNEPLIQVEGRVFEAQLLETAILNFMNYQT 136 Query: 121 LIATKASRIKQVAPKDTLLEFGTRRAQEADAAVWGARAAYISGFHATSNMLAGKKFGIPT 180 L+ATKA+RIKQVAP D L+EFGTRRAQEADAA+WG RAAYI+GF +TSN+ A K FGIP Sbjct: 137 LVATKAARIKQVAPNDVLIEFGTRRAQEADAAIWGTRAAYIAGFDSTSNVRAAKLFGIPC 196 Query: 181 KGTHAHSWVQSFASEQEAFDAYAKVMPDGVTLLVDTFDTLRSGVPHAINTAKMLEAAGKR 240 KGT AHSWV+ SE+EAF +A V PD V LLVDT+DTL+SGVP+AI K LEA GKR Sbjct: 197 KGTIAHSWVEVHRSEEEAFKNFADVFPDNVILLVDTYDTLKSGVPNAIKIGKYLEAKGKR 256 Query: 241 MNAIRLDSGDLAYLSIQARKMLDEAGLDYVKIVASNDLDENTIMNLKSQGAAIDTWGVGT 300 + +IRLDSGDLAYLSIQ+R+MLDEAGLDYVKI AS DLDEN I LK+QGA ID WG+GT Sbjct: 257 LKSIRLDSGDLAYLSIQSRRMLDEAGLDYVKITASGDLDENEIYYLKTQGAKIDIWGIGT 316 Query: 301 QLITASDQPSLGGVYKLVEIESPNGEMVPTIKISSNPEKVSTPGKKEVFRIVGPK-GKAL 359 +LIT +D P+LGGVYKLV E NG VP IKISSNPEK+ TPG K V+RI+ GK+ Sbjct: 317 RLITCADDPALGGVYKLVAKEE-NGSYVPVIKISSNPEKIITPGFKTVYRIINKSTGKSE 375 Query: 360 ADYISFPGEQEPRSGRRLKLFNPLHPYLQKYVEKYEAVSMLEPIFVNGFQVYKLPVLDEI 419 DY++ GE + + R+K+F+P+H ++ KYV +EAV +LEP+FVNG QV++LP L+EI Sbjct: 376 GDYVADVGE-DVKGQHRIKMFDPVHTWIYKYVTNFEAVGLLEPVFVNGEQVFELPALEEI 434 Query: 420 RRYHQEQIDLFWPEYLRKLNPEVYRVNLSELVWTRKQQLIAEH 462 R YH+ Q++LFW EYLR++NPE Y V+LSE VW K LI ++ Sbjct: 435 REYHKSQLNLFWSEYLRRINPEPYPVDLSEKVWNTKMNLIKQY 477 >A4IP15.1 A4IP15_GEOTN Nicotinate phosphoribosyltransferase EC=2.4.2.11 Length = 490 Score = 515 bits (1327), Expect = e-144, Method: Compositional matrix adjust. Identities = 265/462 (57%), Positives = 331/462 (71%), Gaps = 9/462 (1%) Query: 1 MMYAHWVNGSHKRRAVFEAYFRKLPFGNGFAVFAGLERITQYISELRFTEEDIRYLSEQE 60 M+ +W +G H+RRAVFE +FRKLPFGNG+AVFAGLER+ Q++ RF++ DI YL E Sbjct: 21 MVETYWEDGIHERRAVFEVFFRKLPFGNGYAVFAGLERVIQFLQGFRFSDSDINYL-RNE 79 Query: 61 ENYAPAFLEELLQFHFQGSIYSMKEGALVFPDEPLVRVEGTIMEAQLVETAILNFMNYQT 120 Y FL+ L F G++ SMKEG +VF +EP++R+E + EAQL+ETAILN +N+QT Sbjct: 80 LGYRDDFLDYLRTLRFTGTVRSMKEGEIVFANEPIMRIEAPLAEAQLIETAILNIINFQT 139 Query: 121 LIATKASRIKQVAPKDTLLEFGTRRAQEADAAVWGARAAYISGFHATSNMLAGKKFGIPT 180 LIATKASRIK + + LEFG+RRAQE DAA+WGARAAYI G ATSN+ AGK FGIP Sbjct: 140 LIATKASRIKHILGDEPALEFGSRRAQEMDAALWGARAAYIGGIEATSNVRAGKLFGIPV 199 Query: 181 KGTHAHSWVQSFASEQEAFDAYAKVMPDGVTLLVDTFDTLRSGVPHAINTAKMLEAAGKR 240 GTHAHS +Q++ E AF YA+ D V LVDT+DTL+SGVP+AI AK L G + Sbjct: 200 AGTHAHSMIQAYQDEYVAFYKYARRHKDCV-FLVDTYDTLKSGVPNAIRVAKEL---GDK 255 Query: 241 MN--AIRLDSGDLAYLSIQARKMLDEAGLDYVKIVASNDLDENTIMNLKSQGAAIDTWGV 298 +N IR+DSGDLAYLS +ARKMLDEAG KI ASNDLDE+TI+NLKSQGA ID WG+ Sbjct: 256 INFIGIRIDSGDLAYLSKEARKMLDEAGFPNAKIFASNDLDEDTILNLKSQGAKIDVWGI 315 Query: 299 GTQLITASDQPSLGGVYKLVEIESPNGEMVPTIKISSNPEKVSTPGKKEVFRIVGP-KGK 357 GT+LITA DQP+LG VYK+V IE+ GEMV TIKIS NPEKV+TPG K V+RIV K Sbjct: 316 GTKLITAYDQPALGAVYKIVAIENEAGEMVDTIKISGNPEKVTTPGLKRVYRIVNKINHK 375 Query: 358 ALADYISFPGEQEPRSGRRLKLFNPLHPYLQKYVEKYEAVSMLEPIFVNGFQVYKLPVLD 417 A DYI+ E P+ RLK+F+P++ ++ K+V +EA + E IF NG VY P L Sbjct: 376 AEGDYIALESEN-PQQEERLKMFHPVYTFISKFVTNFEARDLHETIFDNGKLVYTSPPLP 434 Query: 418 EIRRYHQEQIDLFWPEYLRKLNPEVYRVNLSELVWTRKQQLI 459 +I+ Y +E + LFW EY R LNPE Y V+LS+ W K + I Sbjct: 435 DIQAYAKESLRLFWEEYKRTLNPEQYPVDLSQACWDNKMENI 476 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.391 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,774,163,152 Number of extensions: 115261492 Number of successful extensions: 299784 Number of sequences better than 1.0e-05: 963 Number of HSP's gapped: 296484 Number of HSP's successfully gapped: 1040 Length of query: 475 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 335 Effective length of database: 1,741,754,103 Effective search space: 583487624505 Effective search space used: 583487624505 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)