BLASTP 2.2.18 [Mar-02-2008]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.

Query= 0504.0037.p
         (651 letters)

Database: pfamseq 
           9,421,015 sequences; 3,060,696,203 total letters

Searching..................................................done



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

A6LZY8.1 A6LZY8_CLOB8 Formate dehydrogenase, alpha subunit           1036   0.0  
Q180G2.1 Q180G2_CLOD6 Formate dehydrogenase H EC=1.2.1.2              993   0.0  
Q2RXL6.1 Q2RXL6_RHORT Formate dehydrogenase alpha subunit EC=1.2...   910   0.0  
A1JU01.1 A1JU01_YERE8 Formate dehydrogenase H                         900   0.0  
C4SQ31.1 C4SQ31_YERFR Formate dehydrogenase H                         897   0.0  

>A6LZY8.1 A6LZY8_CLOB8 Formate dehydrogenase, alpha subunit
          Length = 713

 Score = 1036 bits (2679), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 482/646 (74%), Positives = 556/646 (86%), Gaps = 3/646 (0%)

Query: 1   MIRKEGVLQEVSWEEAIGFTAEKLNAIKEKYGPDAIMGTGSARGPGNEANYVMQKFMRAV 60
           MIRK G L+EVSW+EAI FTAE L  IK KYGPDAIMGTGSARGPGNE NYVMQKFMRAV
Sbjct: 67  MIRKNGELEEVSWDEAIKFTAENLMKIKAKYGPDAIMGTGSARGPGNEPNYVMQKFMRAV 126

Query: 61  IGTNNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIENTDLLLIFGYNAAVTHPIVARR 120
           IGTNNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIE++D+L IFGYN A THPIVARR
Sbjct: 127 IGTNNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIEDSDVLFIFGYNPAETHPIVARR 186

Query: 121 IVKAKQKGAVLIVADPRKTESARIADTWLPLKGGTNMALVNAFGHVLIEEELYDKDYVSN 180
           IVKAK+KGA +IV DPRKT+  R++D WL LKGGTNMALVNAFG+VLI E+LYD DYV  
Sbjct: 187 IVKAKEKGAKVIVTDPRKTDVVRLSDLWLQLKGGTNMALVNAFGNVLINEDLYDHDYVEK 246

Query: 181 FVQGFDEYKANVEKYTPEYAERITGVRAADIRKVMRQYAKSGKAMILYGMGXXXXCQFAQ 240
           + + F++YKA VEKYTPEYAE+ITGV+A  IRK MR YAK+  A ILYGMG    CQF+Q
Sbjct: 247 YTEDFEKYKAEVEKYTPEYAEKITGVKADYIRKAMRTYAKAKNATILYGMGV---CQFSQ 303

Query: 241 AVDVVKGLASLALLTGHFGRESVGIGPVRGQNNVQGSCDMGALPNVYPGYQSVEDAKIRK 300
           AVDVV+GLAS+ALLTG+F R SVGIGPVRGQNNVQG+CDMG +PN YPGYQ V D K+++
Sbjct: 304 AVDVVRGLASIALLTGNFARPSVGIGPVRGQNNVQGTCDMGTIPNNYPGYQLVTDKKVQE 363

Query: 301 KFEKAWGTSLPDKTGYRLTEVPHLILKENKIKAYYIFGEDPVQSDPNAAELREALDQLEL 360
           KFEKAWG  L DK GY LT+VP L+LKE+KIKAYYIFGEDPVQSDPNAAELREALD++E 
Sbjct: 364 KFEKAWGVELSDKNGYFLTQVPELVLKEDKIKAYYIFGEDPVQSDPNAAELREALDKIEF 423

Query: 361 VIVQDIFMNKTALHADVILPATSWGEHDGVYSSADRGFQRIRKAIDPPGDVKPDWQIISE 420
           ++VQDIFMNKTALHADVILP+TSWGEHDGVYSSADRGFQRIRKA++P GDVK DW+IIS 
Sbjct: 424 IVVQDIFMNKTALHADVILPSTSWGEHDGVYSSADRGFQRIRKAVEPLGDVKTDWEIISA 483

Query: 421 VSTAMGYPMAYKNSEEIWDEMRKLCPSFAGASYSKMEALGGVQWPCPSEDHPGTPYLYQG 480
           V+TAMGYPM YKN+EEIWDEMR LCP FAGASY K+E  G V+WPCP+EDH GT YLY+G
Sbjct: 484 VATAMGYPMNYKNTEEIWDEMRSLCPKFAGASYKKIEEQGIVRWPCPTEDHKGTSYLYEG 543

Query: 481 NRFTTPSGKGQLFACEWRAPLEQPDAEYPLTLSTVREVGHYSVRTMTGNCRALSQLSDEP 540
           N+FTTPSGKG+LFACEWR P+E  D EYPL+LSTVREVGHYSVRTMTGNCRAL +L+DEP
Sbjct: 544 NKFTTPSGKGRLFACEWRPPVELTDEEYPLSLSTVREVGHYSVRTMTGNCRALQKLADEP 603

Query: 541 GNIQISLEDAAEHGIADGQLVQVYSRRGHIMARAQVSGRIKKGATYMTYHFWIGACNELT 600
           G IQ+S+EDA E  I D +LV++ SRRG +++RA ++ R+KKG+T+MTY +WIGACNELT
Sbjct: 604 GFIQMSIEDAEELNIKDQELVRITSRRGSVLSRALITERVKKGSTFMTYQWWIGACNELT 663

Query: 601 VDYLDPVSKTPEFKYCAVRIEAISDQAQAEALVRKQYAELRKQMLV 646
            D LDP+SKTPEFKYCA+++E I DQ  AE  +  +Y  +RK+M +
Sbjct: 664 NDSLDPISKTPEFKYCAIKVERIEDQKSAEEYIITEYENIRKKMRI 709


>Q180G2.1 Q180G2_CLOD6 Formate dehydrogenase H EC=1.2.1.2
          Length = 713

 Score =  993 bits (2567), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 468/646 (72%), Positives = 543/646 (84%), Gaps = 6/646 (0%)

Query: 1   MIRKEGVLQEVSWEEAIGFTAEKLNAIKEKYGPDAIMGTGSARGPGNEANYVMQKFMRAV 60
           MIRK+GVL+EV W+EAI +TA +LN IKEKYGPD+IMGTGSARGPGNEANY+MQKFMRA 
Sbjct: 67  MIRKQGVLEEVEWDEAINYTASRLNEIKEKYGPDSIMGTGSARGPGNEANYIMQKFMRAT 126

Query: 61  IGTNNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIENTDLLLIFGYNAAVTHPIVARR 120
           IGTNN+DHCARV H PSVAGL YSLG GAMSNSIPEIEN D+L IFGYN A +HPIVA R
Sbjct: 127 IGTNNVDHCARV-HAPSVAGLAYSLGSGAMSNSIPEIENADVLFIFGYNGADSHPIVANR 185

Query: 121 IVKAKQKGAVLIVADPRKTESARIADTWLPLKGGTNMALVNAFGHVLIEEELYDKDYVSN 180
           IVKAK+ GA LIV DPR TESARIAD  LP+KGGTNM LVNAFG+VLIEE LY+K++V N
Sbjct: 186 IVKAKKNGAKLIVTDPRVTESARIADIHLPIKGGTNMVLVNAFGNVLIEEGLYNKEFVQN 245

Query: 181 FVQGFDEYKANVEKYTPEYAERITGVRAADIRKVMRQYAKSGKAMILYGMGXXXXCQFAQ 240
             QGFDEYK  V+ YT +YAE+ITG+    IRK MR+YAK  KAMILYGMG    CQF Q
Sbjct: 246 HTQGFDEYKEIVKPYTAKYAEKITGIPEELIRKAMREYAKGKKAMILYGMGV---CQFGQ 302

Query: 241 AVDVVKGLASLALLTGHFGRESVGIGPVRGQNNVQGSCDMGALPNVYPGYQSVEDAKIRK 300
           AVDVVKGLAS+ALLTG+FGRESVGIGPVRGQNNVQG+CDMGALPNVYPGYQ+V D KIR+
Sbjct: 303 AVDVVKGLASIALLTGNFGRESVGIGPVRGQNNVQGACDMGALPNVYPGYQNVTDDKIRE 362

Query: 301 KFEKAWGTSLPDKTGYRLTEVPHLILKENKIKAYYIFGEDPVQSDPNAAELREALDQLEL 360
           KFEKAWG  L    GY LT+VP+L+LKE K+KAYYIFGEDPVQSDP+A+E+REALD+LE 
Sbjct: 363 KFEKAWGVKLSPNNGYSLTQVPNLVLKEKKLKAYYIFGEDPVQSDPDASEVREALDELEF 422

Query: 361 VIVQDIFMNKTALHADVILPATSWGEHDGVYSSADRGFQRIRKAIDPPGDVKPDWQIISE 420
           VIVQDIFMNKTALHADVILPATSWGEH+GVY+ ADRGFQ +RKAI+P GDVKPDWQIISE
Sbjct: 423 VIVQDIFMNKTALHADVILPATSWGEHEGVYTCADRGFQLMRKAIEPQGDVKPDWQIISE 482

Query: 421 VSTAMGYPMAYKNSEEIWDEMRKLCPSFAGASYSKMEALGGVQWPCPSE--DHPGTPYLY 478
           +STAMGYPM YKN++EIWDE+R+LCPSF GA+Y K+E  G VQWPC SE  +  GT YLY
Sbjct: 483 ISTAMGYPMNYKNTKEIWDELRQLCPSFLGATYEKIETQGCVQWPCKSESMEDKGTMYLY 542

Query: 479 QGNRFTTPSGKGQLFACEWRAPLEQPDAEYPLTLSTVREVGHYSVRTMTGNCRALSQLSD 538
           +G +F+TP+GKG LFA EWR P+E  D EYP +L TVREVGHYSVRTMTGNCR LS L D
Sbjct: 543 EGQKFSTPNGKGNLFAAEWRPPMEVEDDEYPFSLCTVREVGHYSVRTMTGNCRTLSSLED 602

Query: 539 EPGNIQISLEDAAEHGIADGQLVQVYSRRGHIMARAQVSGRIKKGATYMTYHFWIGACNE 598
           EPG +QI+  DA + GI D +LV++ SRRG ++ RA V+ R+K+GATYMTY +W+GACNE
Sbjct: 603 EPGRVQINSNDAEKLGIEDDELVRISSRRGSVITRATVTDRVKEGATYMTYQWWVGACNE 662

Query: 599 LTVDYLDPVSKTPEFKYCAVRIEAISDQAQAEALVRKQYAELRKQM 644
           LT+  LDP+SKTPE+KYCAV++E + DQ  AE  VR++Y  L+ +M
Sbjct: 663 LTIANLDPISKTPEYKYCAVKLEKLEDQELAEKCVREEYQSLKDKM 708


>Q2RXL6.1 Q2RXL6_RHORT Formate dehydrogenase alpha subunit EC=1.2.1.2
          Length = 713

 Score =  910 bits (2352), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 427/642 (66%), Positives = 512/642 (79%), Gaps = 5/642 (0%)

Query: 4   KEGVLQEVSWEEAIGFTAEKLNAIKEKYGPDAIMGTGSARGPGNEANYVMQKFMRAVIGT 63
           ++   +EVSW EAI F A +L  IK KYGPD+IM TGSARGPGNEANYVMQKF RAV+GT
Sbjct: 71  RDSAFEEVSWYEAINFAATRLQEIKHKYGPDSIMLTGSARGPGNEANYVMQKFARAVVGT 130

Query: 64  NNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIENTDLLLIFGYNAAVTHPIVARRIVK 123
           NNIDHCARVCHGPSVAGL  +LG+GAMSNS+ EIENT  + +FGYNAAV+HPIVARRI+K
Sbjct: 131 NNIDHCARVCHGPSVAGLQVTLGNGAMSNSVEEIENTKCVFVFGYNAAVSHPIVARRILK 190

Query: 124 AKQKGAVLIVADPRKTESARIADTWLPLKGGTNMALVNAFGHVLIEEELYDKDYVSNFVQ 183
           AK+KGA +IV DPR  E+ARIAD WLPLK GTNMALVNAF HVL+EE LYDKD+V+ + +
Sbjct: 191 AKEKGAKIIVCDPRFIETARIADLWLPLKNGTNMALVNAFAHVLLEENLYDKDFVAKYTE 250

Query: 184 GFDEYKANVEKYTPEYAERITGVRAADIRKVMRQYAKSGKAMILYGMGXXXXCQFAQAVD 243
           G D+YKA V KYTPEYAE+ITGV A  IR+ MR YA +  A +++GMG     Q++QAVD
Sbjct: 251 GLDDYKATVAKYTPEYAEKITGVPAQQIREAMRMYAGAETATVMWGMGVT---QWSQAVD 307

Query: 244 VVKGLASLALLTGHFGRESVGIGPVRGQNNVQGSCDMGALPNVYPGYQSVEDAKIRKKFE 303
           VVKGL+ LALLTG+ G+ S G+ PVRGQNNVQG+CD GALPN+ PGYQ V DA  R KFE
Sbjct: 308 VVKGLSGLALLTGNLGKPSCGVAPVRGQNNVQGACDHGALPNMLPGYQPVTDAAARAKFE 367

Query: 304 KAWGTS-LPDKTGYRLTEVPHLILKENKIKAYYIFGEDPVQSDPNAAELREALDQLELVI 362
           KAWG S LPDK G  LTEVP ++ K  K+KAYYIFGEDP Q+DP+  E+RE++  LE VI
Sbjct: 368 KAWGVSNLPDKPGVCLTEVPKMV-KAGKLKAYYIFGEDPAQTDPDLHEVRESMRDLEFVI 426

Query: 363 VQDIFMNKTALHADVILPATSWGEHDGVYSSADRGFQRIRKAIDPPGDVKPDWQIISEVS 422
            Q+IFM KTA+ ADV+ PATSWGEH+GVYSS DRGFQR  KAI+P GDVKPDW+IIS ++
Sbjct: 427 CQEIFMTKTAMMADVVFPATSWGEHEGVYSSCDRGFQRFYKAIEPQGDVKPDWEIISLMA 486

Query: 423 TAMGYPMAYKNSEEIWDEMRKLCPSFAGASYSKMEALGGVQWPCPSEDHPGTPYLYQGNR 482
           TAMGYPM Y N++EIWDE+R+LCP + GA+Y KM  LG +QWPCP  DHPGTPYLY   +
Sbjct: 487 TAMGYPMKYSNTQEIWDELRELCPIYYGATYEKMAGLGYIQWPCPDLDHPGTPYLYADKK 546

Query: 483 FTTPSGKGQLFACEWRAPLEQPDAEYPLTLSTVREVGHYSVRTMTGNCRALSQLSDEPGN 542
           F TPSGKG LFACEWR P+E+ DA YPL LSTVREVGHYS RTMTGNC AL  L+DEPG 
Sbjct: 547 FQTPSGKGLLFACEWRPPMEKVDAAYPLILSTVREVGHYSCRTMTGNCHALQTLADEPGY 606

Query: 543 IQISLEDAAEHGIADGQLVQVYSRRGHIMARAQVSGRIKKGATYMTYHFWIGACNELTVD 602
           I +  +DA   GI+D  LV + SRRG I+ARA +  RI +GA YMTY +W+GACNELT +
Sbjct: 607 ISMHSKDAKALGISDQHLVSISSRRGKIIARADIDDRINEGAVYMTYQWWVGACNELTAE 666

Query: 603 YLDPVSKTPEFKYCAVRIEAISDQAQAEALVRKQYAELRKQM 644
           +LDP+SKTPE+KY AV++EAI+DQA AE  V++ Y++L+  +
Sbjct: 667 HLDPISKTPEYKYSAVKVEAIADQAWAENHVQEVYSQLKADL 708


>A1JU01.1 A1JU01_YERE8 Formate dehydrogenase H
          Length = 715

 Score =  900 bits (2325), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 429/647 (66%), Positives = 518/647 (80%), Gaps = 7/647 (1%)

Query: 1   MIRKE--GVLQEVSWEEAIGFTAEKLNAIKEKYGPDAIMGTGSARGPGNEANYVMQKFMR 58
           MIR++  G L+ VSW+EAI F + KL AIKEKYGP+AIM TGS+RGPGNE NYVMQKF R
Sbjct: 66  MIRRQKGGKLEAVSWDEAIEFASSKLRAIKEKYGPEAIMHTGSSRGPGNETNYVMQKFAR 125

Query: 59  AVIGTNNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIENTDLLLIFGYNAAVTHPIVA 118
           AV G+NNID CARVCHGPSVAGL  +LG+GAMSNSI EIE+T  +L+FGYNAA +HPIVA
Sbjct: 126 AVTGSNNIDCCARVCHGPSVAGLQVTLGNGAMSNSICEIEDTKCILVFGYNAADSHPIVA 185

Query: 119 RRIVKAKQKGAVLIVADPRKTESARIADTWLPLKGGTNMALVNAFGHVLIEEELYDKDYV 178
           RRI+KAK+KGA +IV DPR  E+ARIAD WLPLK G+NMALVNAF +VLI EELYDKDYV
Sbjct: 186 RRILKAKEKGAKVIVCDPRHIETARIADLWLPLKNGSNMALVNAFAYVLITEELYDKDYV 245

Query: 179 SNFVQGFDEYKANVEKYTPEYAERITGVRAADIRKVMRQYAKSGKAMILYGMGXXXXCQF 238
           S + +GFDEY+A V KYTPEY E ITG+ A  IR+ MR YA +  A IL+GMG     Q+
Sbjct: 246 SRYTEGFDEYRAIVAKYTPEYVESITGLPAHTIREAMRIYAAAPSATILWGMGVT---QW 302

Query: 239 AQAVDVVKGLASLALLTGHFGRESVGIGPVRGQNNVQGSCDMGALPNVYPGYQSVEDAKI 298
            Q VDVVKGL+ LALLTG+ GR +VG+GPVRGQNNVQG+CDMGALPN+YPGYQ+V D   
Sbjct: 303 GQGVDVVKGLSGLALLTGNLGRPNVGVGPVRGQNNVQGACDMGALPNMYPGYQAVTDPAT 362

Query: 299 RKKFEKAWGT-SLPDKTGYRLTEVPHLILKENKIKAYYIFGEDPVQSDPNAAELREALDQ 357
            +KF KAWG  SL  K GY LT+VPH + KE KIKA Y+ GEDP+Q++P+ + +REA  +
Sbjct: 363 LEKFAKAWGVPSLSGKIGYSLTDVPHKV-KEGKIKANYVMGEDPLQTEPDLSMMREAFSE 421

Query: 358 LELVIVQDIFMNKTALHADVILPATSWGEHDGVYSSADRGFQRIRKAIDPPGDVKPDWQI 417
           LEL+IVQDIFM KTA  ADVI PATSWGEH+GVYS+ADRGFQR  KA++P GDVKPDW+I
Sbjct: 422 LELLIVQDIFMTKTAAEADVIFPATSWGEHEGVYSAADRGFQRFEKAVEPQGDVKPDWEI 481

Query: 418 ISEVSTAMGYPMAYKNSEEIWDEMRKLCPSFAGASYSKMEALGGVQWPCPSEDHPGTPYL 477
           IS ++TA+GYPM Y N++EIWDE+R+LCP + GA+Y KM  LG V WPC +ED PGTP+L
Sbjct: 482 ISLMATALGYPMKYNNTKEIWDELRELCPLYYGATYEKMAGLGYVPWPCTTEDSPGTPWL 541

Query: 478 YQGNRFTTPSGKGQLFACEWRAPLEQPDAEYPLTLSTVREVGHYSVRTMTGNCRALSQLS 537
           Y GN+F  P GKG LFA EWRAP+EQ D EYPL L TVREVGHYS R+MTGNC AL  L+
Sbjct: 542 YAGNKFDRPGGKGLLFASEWRAPMEQVDEEYPLVLCTVREVGHYSCRSMTGNCSALQTLA 601

Query: 538 DEPGNIQISLEDAAEHGIADGQLVQVYSRRGHIMARAQVSGRIKKGATYMTYHFWIGACN 597
           DEPG +QIS +DA +  + D QLV V SRRG ++ R  VS RI  GA YMTY +WIGACN
Sbjct: 602 DEPGYVQISPQDADKMRLQDQQLVWVASRRGKVITRVSVSERINVGAVYMTYQWWIGACN 661

Query: 598 ELTVDYLDPVSKTPEFKYCAVRIEAISDQAQAEALVRKQYAELRKQM 644
           ELT+D+LDP+SKTPE+KYCAV++EAI+DQ  AE  V+++Y++L+ ++
Sbjct: 662 ELTLDHLDPISKTPEYKYCAVKLEAIADQTWAENYVQQEYSQLKARL 708


>C4SQ31.1 C4SQ31_YERFR Formate dehydrogenase H
          Length = 715

 Score =  897 bits (2317), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 426/647 (65%), Positives = 515/647 (79%), Gaps = 7/647 (1%)

Query: 1   MIRKE--GVLQEVSWEEAIGFTAEKLNAIKEKYGPDAIMGTGSARGPGNEANYVMQKFMR 58
           MIR++  G L+ VSW+EAI F + KL  IKEKYGP+AIM TGS+RGPGNE NYVMQKF R
Sbjct: 66  MIRRQKGGKLEAVSWDEAIEFASSKLREIKEKYGPEAIMHTGSSRGPGNETNYVMQKFAR 125

Query: 59  AVIGTNNIDHCARVCHGPSVAGLTYSLGDGAMSNSIPEIENTDLLLIFGYNAAVTHPIVA 118
           AV G+NNID CARVCHGPSVAGL  +LG+GAMSNSI EIE+T  +L+FGYNAA +HPIVA
Sbjct: 126 AVTGSNNIDCCARVCHGPSVAGLQVTLGNGAMSNSICEIEDTKCILVFGYNAADSHPIVA 185

Query: 119 RRIVKAKQKGAVLIVADPRKTESARIADTWLPLKGGTNMALVNAFGHVLIEEELYDKDYV 178
           RRI+KAK+KGA +IV DPR  E+ARIAD WLPLK G+NMALVNAF +VLI EELYDKDYV
Sbjct: 186 RRILKAKEKGAKVIVCDPRHIETARIADLWLPLKNGSNMALVNAFANVLITEELYDKDYV 245

Query: 179 SNFVQGFDEYKANVEKYTPEYAERITGVRAADIRKVMRQYAKSGKAMILYGMGXXXXCQF 238
           S + +GFDEY+  V KYTPEY E ITG+ A  IR+ MR YA +  A IL+GMG     Q+
Sbjct: 246 SRYTEGFDEYREIVAKYTPEYVESITGLSAQTIRQAMRIYAAAPSATILWGMGVT---QW 302

Query: 239 AQAVDVVKGLASLALLTGHFGRESVGIGPVRGQNNVQGSCDMGALPNVYPGYQSVEDAKI 298
            Q VDVVKGL+ LALLTG+ GR +VG+GPVRGQNNVQG+CDMGALPN+YPGYQ+V D   
Sbjct: 303 GQGVDVVKGLSGLALLTGNLGRPNVGVGPVRGQNNVQGACDMGALPNMYPGYQAVTDPAT 362

Query: 299 RKKFEKAWGT-SLPDKTGYRLTEVPHLILKENKIKAYYIFGEDPVQSDPNAAELREALDQ 357
            +KF KAWG  SL  K GY LT+VPH + KE KIKA Y+ GEDP+Q++P+ + +REA  +
Sbjct: 363 LEKFAKAWGVPSLSGKIGYSLTDVPHKV-KEGKIKANYVMGEDPLQTEPDLSMMREAFSE 421

Query: 358 LELVIVQDIFMNKTALHADVILPATSWGEHDGVYSSADRGFQRIRKAIDPPGDVKPDWQI 417
           LEL+IVQDIFM KTA  ADVI PATSWGEH+GVYS+ADRGFQR  KA+DP GDVKPDW+I
Sbjct: 422 LELLIVQDIFMTKTAAEADVIFPATSWGEHEGVYSAADRGFQRFEKAVDPQGDVKPDWEI 481

Query: 418 ISEVSTAMGYPMAYKNSEEIWDEMRKLCPSFAGASYSKMEALGGVQWPCPSEDHPGTPYL 477
           IS ++TA+GYPM Y N++EIWDE+R+LCP + GA+Y KM  LG + WPC +ED PGTP+L
Sbjct: 482 ISLMATALGYPMKYNNTQEIWDELRELCPLYYGATYEKMAGLGYIPWPCTTEDSPGTPWL 541

Query: 478 YQGNRFTTPSGKGQLFACEWRAPLEQPDAEYPLTLSTVREVGHYSVRTMTGNCRALSQLS 537
           Y GN+F  P GKG LFA EWRAP+EQ D EYPL L TVREVGHYS R+MTGNC AL  L+
Sbjct: 542 YAGNKFDRPGGKGLLFASEWRAPMEQVDEEYPLVLCTVREVGHYSCRSMTGNCSALQTLA 601

Query: 538 DEPGNIQISLEDAAEHGIADGQLVQVYSRRGHIMARAQVSGRIKKGATYMTYHFWIGACN 597
           DEPG +QIS +DA +  + D QLV V SRRG ++ R  VS RI  GA YMTY +WIGACN
Sbjct: 602 DEPGYVQISPQDANKMHLKDQQLVWVESRRGKVITRVSVSERINVGAVYMTYQWWIGACN 661

Query: 598 ELTVDYLDPVSKTPEFKYCAVRIEAISDQAQAEALVRKQYAELRKQM 644
           ELT+D+LDP+SKTPE+KYCAV++E I+DQ  AE  V+++Y++L+ ++
Sbjct: 662 ELTLDHLDPISKTPEYKYCAVKLEPIADQTWAENYVQQEYSQLKARL 708


  Database: pfamseq
    Posted date:  Aug 5, 2010  3:22 PM
  Number of letters in database: 3,060,696,203
  Number of sequences in database:  9,421,015
  
Lambda     K      H
   0.317    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Sequences: 9421015
Number of Hits to DB: 4,020,611,620
Number of extensions: 173799577
Number of successful extensions: 417695
Number of sequences better than 1.0e-05: 5930
Number of HSP's gapped: 400149
Number of HSP's successfully gapped: 7334
Length of query: 651
Length of database: 3,060,696,203
Length adjustment: 142
Effective length of query: 509
Effective length of database: 1,722,912,073
Effective search space: 876962245157
Effective search space used: 876962245157
Neighboring words threshold: 11
Window for multiple hits: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 135 (56.6 bits)