BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0504.0033.p (512 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DLK1.1 B1DLK1_9BACL Glucose-6-phosphate 1-dehydrogenase EC=1.1... 590 e-167 B5ULI3.1 B5ULI3_BACCE Glucose-6-phosphate 1-dehydrogenase EC=1.1... 571 e-161 Q4MXU9.1 Q4MXU9_BACCE Glucose-6-phosphate 1-dehydrogenase EC=1.1... 567 e-160 C2XE48.1 C2XE48_BACCE Glucose-6-phosphate 1-dehydrogenase 567 e-160 C2PHR0.1 C2PHR0_BACCE Glucose-6-phosphate 1-dehydrogenase 567 e-160 >B1DLK1.1 B1DLK1_9BACL Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 503 Score = 590 bits (1522), Expect = e-167, Method: Compositional matrix adjust. Identities = 291/487 (59%), Positives = 354/487 (72%), Gaps = 6/487 (1%) Query: 3 VESSTFVLFGATGDLAKRKIFPALYNLFADGKLSGPLFVIGLGRRTLTNESFQAGVLDSL 62 +E TFVLFGATGDLAKRKI+PALYNLF DGKL +IGLGRR T+E FQ+ + SL Sbjct: 1 MEPVTFVLFGATGDLAKRKIYPALYNLFVDGKLPEAFSLIGLGRREWTDEFFQSNIEQSL 60 Query: 63 HAFSRRKVEDSPELQRFLKSFEYSVLDVGHPEDYRKLLGHVQRREEELGLPQNRMFYLSV 122 FSRR+++D +Q F++ F Y+VLD+G +DY+KLLG ++ RE L LP NRMFYLSV Sbjct: 61 RQFSRREIQDQALMQSFIRKFRYTVLDIGRTDDYKKLLGIIEERESALQLPPNRMFYLSV 120 Query: 123 GPEFFGEIAANINASGLGDTRGWKRLIIEKPFGTDLESARVLNDSLNAAFTEEEIFRIDH 182 GPE+F IA+NI SGLG T GWKRL+IEKPFG DL+SAR LN+ L+ +F EEEIFRIDH Sbjct: 121 GPEYFTTIASNIAESGLGSTAGWKRLVIEKPFGHDLQSARDLNEQLSKSFAEEEIFRIDH 180 Query: 183 FLGKPMVQNLEVLKYSNPVLRALWQNRYIANVQITASETVGVEERAGYYDKAGALRDMFQ 242 +LGKPMVQNLEVL+ +NP+++ALW NRYIANVQITASETVGVEERAGYYD GA+RDMFQ Sbjct: 181 YLGKPMVQNLEVLESANPIIQALWSNRYIANVQITASETVGVEERAGYYDHVGAVRDMFQ 240 Query: 243 NHXXXXXXXXXXXXPKGSTPEDVRSKKRHVIQSVRPLLRENLAQNVIRGQYAAGEIKGRP 302 NH P S+PEDVR K+ V++++ PL + ++ NVIRGQY +G I G P Sbjct: 241 NHMLQMLMMLAIHLPHNSSPEDVRKHKKQVMEALIPLSKSEVSANVIRGQYTSGSIGGTP 300 Query: 303 VDAYTSEPGIGPSSQNETYIAARLFIDDPLWDEVPFYIRTGKRMKEKSTRIVIEFKEPFX 362 V Y SEPGI SS N+TYIAA+L +DD W VPFYIRTGKR+ EKSTRIV+EFKE Sbjct: 301 VKDYRSEPGIAASSVNDTYIAAKLQVDDYFWRGVPFYIRTGKRLHEKSTRIVVEFKEAL- 359 Query: 363 XXXXXXXXXXXXXXXXXXXGPEEGISLQLNTKNPRQHGQLEPVSIRHDSANPELPEAYEN 422 P EGI LQLNTK ++G+L+PV I+ ++ ++PEAYEN Sbjct: 360 HQASTAALGGAPNLLLIEINPNEGIMLQLNTK---ENGELKPVQIQLHESSKDIPEAYEN 416 Query: 423 LIYDALLGDATFFAHWDEVELSWQWVQPIIEATAGGTLPLHLYPAGSNGPAAADELLGDA 482 LIYDAL+G+ TFFAHWDEVEL+W WVQPI++A +PL Y AGSNGPA AD LL + Sbjct: 417 LIYDALVGNPTFFAHWDEVELAWAWVQPILDAFQENLVPLASYEAGSNGPAEADALLAED 476 Query: 483 --HWWLD 487 HWW D Sbjct: 477 GFHWWFD 483 >B5ULI3.1 B5ULI3_BACCE Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 494 Score = 571 bits (1472), Expect = e-161, Method: Compositional matrix adjust. Identities = 282/492 (57%), Positives = 355/492 (72%), Gaps = 4/492 (0%) Query: 3 VESSTFVLFGATGDLAKRKIFPALYNLFADGKLSGPLFVIGLGRRTLTNESFQAGVLDSL 62 +ES TFVLFGATGDLAKRKI+PALYNL+ D KL + VIGLGRR +++E FQ + +S+ Sbjct: 1 MESMTFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRRQVSHEDFQERIKESI 60 Query: 63 HAFSRRKVEDSPELQRFLKSFEYSVLDVGHPEDYRKLLGHVQRREEELGLPQNRMFYLSV 122 FSR++ E +PEL+ FL +F Y LDV PEDY +LL V+ REEEL + NRMFYLSV Sbjct: 61 ETFSRQREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSV 120 Query: 123 GPEFFGEIAANINASGLGDTRGWKRLIIEKPFGTDLESARVLNDSLNAAFTEEEIFRIDH 182 PEFF IA NI SGL T GWKRL+IEKPFG DL SAR LND L+ F E+EI+RIDH Sbjct: 121 APEFFETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDH 180 Query: 183 FLGKPMVQNLEVLKYSNPVLRALWQNRYIANVQITASETVGVEERAGYYDKAGALRDMFQ 242 +LGKPM+QNLE L+++NPVL+++W +IANVQITASETVGVEERAGYYD+AGA+RDM Q Sbjct: 181 YLGKPMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQ 240 Query: 243 NHXXXXXXXXXXXXPKGSTPEDVRSKKRHVIQSVRPLLRENLAQNVIRGQYAAGEIKGRP 302 NH P+ ++R +KR V++++R + +E++ ++IRGQYAAGEIKG Sbjct: 241 NHMLQILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQSHIIRGQYAAGEIKGGQ 300 Query: 303 VDAYTSEPGIGPSSQNETYIAARLFIDDPLWDEVPFYIRTGKRMKEKSTRIVIEFKEPFX 362 V AY EPG+ PSS +T++AARL+ID+P W VPFYIRTGKRMKEKSTRIVIEFK Sbjct: 301 VVAYKEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLK 360 Query: 363 XXXXXXXXXXXXXXXXXXXGPEEGISLQLNTKNPRQHGQLEPVSIRH--DSANPELPEAY 420 P E +SLQLN+KNP ++G++EP+ I + A+ +PEAY Sbjct: 361 QQYQDNNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQADVGVPEAY 420 Query: 421 ENLIYDALLGDATFFAHWDEVELSWQWVQPIIEATAGGTLPLHLYPAGSNGPAAADELLG 480 E LI+DA+ GDATFFAHW EVELSW+WVQPI+EA LPLH Y +GS GP A++ELL Sbjct: 421 ERLIHDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQ 480 Query: 481 DA--HWWLDEPT 490 ++ WWLD+ T Sbjct: 481 ESGFKWWLDQET 492 >Q4MXU9.1 Q4MXU9_BACCE Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 491 Score = 567 bits (1462), Expect = e-160, Method: Compositional matrix adjust. Identities = 279/488 (57%), Positives = 352/488 (72%), Gaps = 4/488 (0%) Query: 7 TFVLFGATGDLAKRKIFPALYNLFADGKLSGPLFVIGLGRRTLTNESFQAGVLDSLHAFS 66 TFVLFGATGDLAKRKI+PALYNL+ D KL + VIGLGRR +++E FQ + +S+ FS Sbjct: 2 TFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRRQVSHEDFQERIKESIETFS 61 Query: 67 RRKVEDSPELQRFLKSFEYSVLDVGHPEDYRKLLGHVQRREEELGLPQNRMFYLSVGPEF 126 R++ E +PEL+ FL +F Y LDV PEDY +LL V+ REEEL + NRMFYLSV PEF Sbjct: 62 RKREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPEF 121 Query: 127 FGEIAANINASGLGDTRGWKRLIIEKPFGTDLESARVLNDSLNAAFTEEEIFRIDHFLGK 186 F IA NI SGL T GWKRL+IEKPFG DL SAR LND L+ F E+EI+RIDH+LGK Sbjct: 122 FETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDHYLGK 181 Query: 187 PMVQNLEVLKYSNPVLRALWQNRYIANVQITASETVGVEERAGYYDKAGALRDMFQNHXX 246 PM+QNLE L+++NPVL+++W +IANVQITASETVGVEERAGYYD+AGA+RDM QNH Sbjct: 182 PMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHML 241 Query: 247 XXXXXXXXXXPKGSTPEDVRSKKRHVIQSVRPLLRENLAQNVIRGQYAAGEIKGRPVDAY 306 P+ ++R +KR V++++R + +E++ ++IRGQYA+GEIKG V AY Sbjct: 242 QILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQNHIIRGQYASGEIKGGQVVAY 301 Query: 307 TSEPGIGPSSQNETYIAARLFIDDPLWDEVPFYIRTGKRMKEKSTRIVIEFKEPFXXXXX 366 EPG+ PSS +T++AARL+ID+P W VPFYIRTGKRMKEKSTRIVIEFK Sbjct: 302 KEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQYQ 361 Query: 367 XXXXXXXXXXXXXXXGPEEGISLQLNTKNPRQHGQLEPVSIRH--DSANPELPEAYENLI 424 P E +SLQLN+KNP ++G++EP+ I + A+ +PEAYE LI Sbjct: 362 DSNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQADVGVPEAYERLI 421 Query: 425 YDALLGDATFFAHWDEVELSWQWVQPIIEATAGGTLPLHLYPAGSNGPAAADELLGDA-- 482 +DA+ GDATFFAHW EVELSW+WVQPI+EA LPLH Y +GS GP A++ELL ++ Sbjct: 422 HDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESGF 481 Query: 483 HWWLDEPT 490 WWLD+ T Sbjct: 482 KWWLDQET 489 >C2XE48.1 C2XE48_BACCE Glucose-6-phosphate 1-dehydrogenase Length = 491 Score = 567 bits (1462), Expect = e-160, Method: Compositional matrix adjust. Identities = 280/488 (57%), Positives = 352/488 (72%), Gaps = 4/488 (0%) Query: 7 TFVLFGATGDLAKRKIFPALYNLFADGKLSGPLFVIGLGRRTLTNESFQAGVLDSLHAFS 66 TFVLFGATGDLAKRKI+PALYNL+ D KL + VIGLGRR +++E FQ + +S+ FS Sbjct: 2 TFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRRQVSHEDFQERIKESIETFS 61 Query: 67 RRKVEDSPELQRFLKSFEYSVLDVGHPEDYRKLLGHVQRREEELGLPQNRMFYLSVGPEF 126 R++ E +PEL+ FL +F Y LDV PEDY +LL V+ REEEL + NRMFYLSV PEF Sbjct: 62 RQREEGTPELEGFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIKGNRMFYLSVAPEF 121 Query: 127 FGEIAANINASGLGDTRGWKRLIIEKPFGTDLESARVLNDSLNAAFTEEEIFRIDHFLGK 186 F IA NI SGL T GWKRL+IEKPFG DL SAR LND L+ F E+EI+RIDH+LGK Sbjct: 122 FETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDHYLGK 181 Query: 187 PMVQNLEVLKYSNPVLRALWQNRYIANVQITASETVGVEERAGYYDKAGALRDMFQNHXX 246 PM+QNLE L+++NPVL+++W +IANVQITASETVGVEERAGYYD+AGA+RDM QNH Sbjct: 182 PMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHML 241 Query: 247 XXXXXXXXXXPKGSTPEDVRSKKRHVIQSVRPLLRENLAQNVIRGQYAAGEIKGRPVDAY 306 P+ ++R +KR V++++R + +E++ ++IRGQYAAGEIKG V AY Sbjct: 242 QILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVQSHIIRGQYAAGEIKGGQVVAY 301 Query: 307 TSEPGIGPSSQNETYIAARLFIDDPLWDEVPFYIRTGKRMKEKSTRIVIEFKEPFXXXXX 366 EPG+ PSS +T++AARL+ID+P W VPFYIRTGKRMKEKSTRIVIEFK Sbjct: 302 KEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQYQ 361 Query: 367 XXXXXXXXXXXXXXXGPEEGISLQLNTKNPRQHGQLEPVSIRH--DSANPELPEAYENLI 424 P E +SLQLN+KNP ++G++EP+ I + A+ +PEAYE LI Sbjct: 362 DNNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQADVGVPEAYERLI 421 Query: 425 YDALLGDATFFAHWDEVELSWQWVQPIIEATAGGTLPLHLYPAGSNGPAAADELLGDA-- 482 +DA+ GDATFFAHW EVELSW+WVQPI+EA LPLH Y +GS GP A++ELL ++ Sbjct: 422 HDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESGF 481 Query: 483 HWWLDEPT 490 WWLD+ T Sbjct: 482 KWWLDQET 489 >C2PHR0.1 C2PHR0_BACCE Glucose-6-phosphate 1-dehydrogenase Length = 491 Score = 567 bits (1462), Expect = e-160, Method: Compositional matrix adjust. Identities = 279/488 (57%), Positives = 350/488 (71%), Gaps = 4/488 (0%) Query: 7 TFVLFGATGDLAKRKIFPALYNLFADGKLSGPLFVIGLGRRTLTNESFQAGVLDSLHAFS 66 TFVLFGATGDLAKRKI+PALYNL+ D KL + VIGLGRR +++E FQ + +S+ FS Sbjct: 2 TFVLFGATGDLAKRKIYPALYNLYRDQKLPKQISVIGLGRRQVSHEDFQKRIKESIETFS 61 Query: 67 RRKVEDSPELQRFLKSFEYSVLDVGHPEDYRKLLGHVQRREEELGLPQNRMFYLSVGPEF 126 R + ED+PEL+ FL +F Y LDV PEDY +LL V+ REEEL + NRMFYLSV PEF Sbjct: 62 RHREEDTPELESFLDNFRYCPLDVSKPEDYERLLQVVREREEELHIQGNRMFYLSVAPEF 121 Query: 127 FGEIAANINASGLGDTRGWKRLIIEKPFGTDLESARVLNDSLNAAFTEEEIFRIDHFLGK 186 F IA NI SGL T GWKRL+IEKPFG DL SAR LND L+ F E+EI+RIDH+LGK Sbjct: 122 FETIALNIKESGLDKTDGWKRLMIEKPFGHDLTSARELNDKLSRTFEEDEIYRIDHYLGK 181 Query: 187 PMVQNLEVLKYSNPVLRALWQNRYIANVQITASETVGVEERAGYYDKAGALRDMFQNHXX 246 PM+QNLE L+++NPVL+++W +IANVQITASETVGVEERAGYYD+AGA+RDM QNH Sbjct: 182 PMIQNLEALEFANPVLQSIWNKEHIANVQITASETVGVEERAGYYDQAGAIRDMVQNHML 241 Query: 247 XXXXXXXXXXPKGSTPEDVRSKKRHVIQSVRPLLRENLAQNVIRGQYAAGEIKGRPVDAY 306 P+ ++R +KR V++++R + +E++ ++IRGQY AGEI G V AY Sbjct: 242 QILMMTAMNLPEKVNACEIREEKRKVMETLRKVKKEDVHNHIIRGQYGAGEINGGQVVAY 301 Query: 307 TSEPGIGPSSQNETYIAARLFIDDPLWDEVPFYIRTGKRMKEKSTRIVIEFKEPFXXXXX 366 EPG+ PSS +T++AARL+ID+P W VPFYIRTGKRMKEKSTRIVIEFK Sbjct: 302 KEEPGVNPSSNIDTFVAARLWIDNPFWTGVPFYIRTGKRMKEKSTRIVIEFKNTLKQQYQ 361 Query: 367 XXXXXXXXXXXXXXXGPEEGISLQLNTKNPRQHGQLEPVSIRH--DSANPELPEAYENLI 424 P E +SLQLN+KNP ++G++EP+ I + A+ +PEAYE LI Sbjct: 362 DNNPNAAPNLLIIEISPGENVSLQLNSKNPLKNGEIEPMRINFTCEQADVGVPEAYERLI 421 Query: 425 YDALLGDATFFAHWDEVELSWQWVQPIIEATAGGTLPLHLYPAGSNGPAAADELLGDAH- 483 +DA+ GDATFFAHW EVELSW+WVQPI+EA LPLH Y +GS GP A++ELL ++ Sbjct: 422 HDAVSGDATFFAHWREVELSWEWVQPILEAFEENLLPLHEYESGSYGPEASNELLQESEF 481 Query: 484 -WWLDEPT 490 WWLD+ T Sbjct: 482 KWWLDQET 489 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.136 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,002,598,083 Number of extensions: 126945019 Number of successful extensions: 271121 Number of sequences better than 1.0e-05: 2143 Number of HSP's gapped: 264657 Number of HSP's successfully gapped: 2166 Length of query: 512 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 372 Effective length of database: 1,741,754,103 Effective search space: 647932526316 Effective search space used: 647932526316 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 134 (56.2 bits)