BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0502.0004.p (206 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2P8C0.1 C2P8C0_BACCE Transcriptional regulator, TetR 167 6e-40 C3A521.1 C3A521_BACMY Transcriptional regulator, TetR 163 9e-39 C3HZP9.1 C3HZP9_BACTU Transcriptional regulator, TetR 163 1e-38 C2PV36.1 C2PV36_BACCE Transcriptional regulator, TetR 162 1e-38 Q3EPB8.1 Q3EPB8_BACTI Transcriptional regulator, TetR family 162 2e-38 >C2P8C0.1 C2P8C0_BACCE Transcriptional regulator, TetR Length = 203 Score = 167 bits (422), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 80/202 (39%), Positives = 130/202 (64%), Gaps = 5/202 (2%) Query: 4 NDSIADHADKDTKQTILEATVDLIRAYGFSCATMRNIAAKAETNLALVNYHYGSKEKLLA 63 D + ++ + TK+ IL T++LI+ GF T+R IA ++TN+ALVNYH+GSKEKL++ Sbjct: 6 GDKLRENENISTKEKILNTTLELIKNEGFESVTIRKIAVLSDTNIALVNYHFGSKEKLIS 65 Query: 64 DAVRVLLSTFDDAFKVLEDDTVPPRERLKEFFIRYIEELKRYPGMARQMLEQRHHIMSSL 123 + ++VLL +F D F +L+D +P +ERLK F + Y+ +++YP + R+++ + +S Sbjct: 66 ETIKVLLISFKDTFSILDDTKLPAKERLKIFLLNYVIVIRQYPELVRKIIAMGTTVFTSQ 125 Query: 124 DEYSRYCKMMRLEKILQAIQEITGEQDKNKLMMMQLQIYGAVVVPEIMLSSLPADKADFM 183 EY + K + K+ + EIT E D+ LMMM +QI+G++ +P +M+ L + AD Sbjct: 126 YEYGDFLKRLGFSKVKNILSEITNETDREILMMMTVQIFGSIFLPALMMPILESG-AD-- 182 Query: 184 PVFNPPPIEEQIDGLFERYFHQ 205 PIE+QID LFERYF++ Sbjct: 183 --IRIQPIEKQIDFLFERYFYK 202 >C3A521.1 C3A521_BACMY Transcriptional regulator, TetR Length = 195 Score = 163 bits (413), Expect = 9e-39, Method: Compositional matrix adjust. Identities = 80/199 (40%), Positives = 130/199 (65%), Gaps = 5/199 (2%) Query: 7 IADHADKDTKQTILEATVDLIRAYGFSCATMRNIAAKAETNLALVNYHYGSKEKLLADAV 66 + ++ + TK+ IL T++LI+ GF T+R IA+ ++ N+ALVNYH+GSKEKL+++A+ Sbjct: 1 MGENENISTKEKILNTTLELIKNEGFERVTIRKIASLSDVNIALVNYHFGSKEKLISEAI 60 Query: 67 RVLLSTFDDAFKVLEDDTVPPRERLKEFFIRYIEELKRYPGMARQMLEQRHHIMSSLDEY 126 +VLL +F F +L+D TVP +ERLK F Y+ +++YP + R+++ + +S EY Sbjct: 61 KVLLISFQGTFSILDDITVPAKERLKIFLFDYVLVIRQYPELVRKIIAMGTTVFTSQYEY 120 Query: 127 SRYCKMMRLEKILQAIQEITGEQDKNKLMMMQLQIYGAVVVPEIMLSSLPADKADFMPVF 186 + K + K+ + EIT E D+ LMMM +QI+G++ +P +M+ L + AD + Sbjct: 121 GDFLKRLGFSKVKNILSEITNEADQEILMMMTVQIFGSIFLPALMMPILESG-ADIRVL- 178 Query: 187 NPPPIEEQIDGLFERYFHQ 205 PIE+QID LFERYF++ Sbjct: 179 ---PIEKQIDFLFERYFYK 194 >C3HZP9.1 C3HZP9_BACTU Transcriptional regulator, TetR Length = 195 Score = 163 bits (412), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 79/196 (40%), Positives = 127/196 (64%), Gaps = 5/196 (2%) Query: 10 HADKDTKQTILEATVDLIRAYGFSCATMRNIAAKAETNLALVNYHYGSKEKLLADAVRVL 69 + + TK+ IL T++LI+ GF T+R IAA ++ N+ALVNYH+GSKEKL+++ +RVL Sbjct: 4 NENVSTKEKILNTTLELIKKEGFERVTIRKIAALSDVNIALVNYHFGSKEKLISETIRVL 63 Query: 70 LSTFDDAFKVLEDDTVPPRERLKEFFIRYIEELKRYPGMARQMLEQRHHIMSSLDEYSRY 129 L +F F +L++ TVP +ERLK F + Y+ +++YP + R+++ + +S EY + Sbjct: 64 LISFQGTFSILDNITVPAKERLKIFLLDYVLVIRQYPELVRKIIAMGTTVFTSQYEYGDF 123 Query: 130 CKMMRLEKILQAIQEITGEQDKNKLMMMQLQIYGAVVVPEIMLSSLPADKADFMPVFNPP 189 K + K+ + EIT E D+ LMMM +QI+G++ +P +M+ L + AD P Sbjct: 124 LKRLGFSKVKNILSEITNETDQEILMMMTVQIFGSIFLPTLMMPILESG-AD----IKVP 178 Query: 190 PIEEQIDGLFERYFHQ 205 +E+QID LFERYF++ Sbjct: 179 SVEKQIDFLFERYFYK 194 >C2PV36.1 C2PV36_BACCE Transcriptional regulator, TetR Length = 195 Score = 162 bits (411), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 83/205 (40%), Positives = 132/205 (64%), Gaps = 11/205 (5%) Query: 1 MNRNDSIADHADKDTKQTILEATVDLIRAYGFSCATMRNIAAKAETNLALVNYHYGSKEK 60 M N++I+ TK+ IL T++LI+ GF T+R IA+ ++ N+ALVNYH+GSKEK Sbjct: 1 MGGNENIS------TKEKILNTTLELIKNEGFERVTIRKIASLSDVNIALVNYHFGSKEK 54 Query: 61 LLADAVRVLLSTFDDAFKVLEDDTVPPRERLKEFFIRYIEELKRYPGMARQMLEQRHHIM 120 L+++A++VLL +F F +L+D TVP +ERLK F Y+ +++YP + R+++ + Sbjct: 55 LISEAIKVLLISFQGTFSILDDITVPAKERLKIFLFDYVLVIRQYPELVRKIIAMGTTVF 114 Query: 121 SSLDEYSRYCKMMRLEKILQAIQEITGEQDKNKLMMMQLQIYGAVVVPEIMLSSLPADKA 180 +S EY + K + K+ + EIT E D+ LMMM +QI+G++ +P +M+ L + A Sbjct: 115 TSQYEYGDFLKRLGFSKVKNILSEITNEADQEILMMMTVQIFGSIFLPALMMPILESG-A 173 Query: 181 DFMPVFNPPPIEEQIDGLFERYFHQ 205 D + PIE+QID LFERYF++ Sbjct: 174 DIRVL----PIEKQIDFLFERYFYK 194 >Q3EPB8.1 Q3EPB8_BACTI Transcriptional regulator, TetR family Length = 195 Score = 162 bits (410), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 79/199 (39%), Positives = 127/199 (63%), Gaps = 5/199 (2%) Query: 7 IADHADKDTKQTILEATVDLIRAYGFSCATMRNIAAKAETNLALVNYHYGSKEKLLADAV 66 + + + TK+ IL T++LI+ GF T+R IAA ++ N+ALVNYH+GSKEKL+++ + Sbjct: 1 MGGNENVSTKEKILNTTLELIKKEGFERVTIRKIAALSDVNIALVNYHFGSKEKLISETI 60 Query: 67 RVLLSTFDDAFKVLEDDTVPPRERLKEFFIRYIEELKRYPGMARQMLEQRHHIMSSLDEY 126 RVLL +F F +L++ TVP +ERLK F + Y+ +++YP + R+++ +S EY Sbjct: 61 RVLLISFQGTFSILDNITVPAKERLKIFLLDYVLVIRQYPKLVRKIIAMGTTAFTSQYEY 120 Query: 127 SRYCKMMRLEKILQAIQEITGEQDKNKLMMMQLQIYGAVVVPEIMLSSLPADKADFMPVF 186 + K + K+ + EIT E D+ LMMM +QI+G++ +P +M+ L + AD Sbjct: 121 GDFLKRLGFSKVKNILSEITNETDQEILMMMTVQIFGSIFLPTLMMPILESG-AD----I 175 Query: 187 NPPPIEEQIDGLFERYFHQ 205 P +E+QID LFERYF++ Sbjct: 176 KVPSVEKQIDFLFERYFYK 194 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.322 0.136 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,156,788,531 Number of extensions: 42355839 Number of successful extensions: 135792 Number of sequences better than 1.0e-05: 71 Number of HSP's gapped: 136080 Number of HSP's successfully gapped: 71 Length of query: 206 Length of database: 3,060,696,203 Length adjustment: 129 Effective length of query: 77 Effective length of database: 1,845,385,268 Effective search space: 142094665636 Effective search space used: 142094665636 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 128 (53.9 bits)