BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0498.0007.p (599 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K3A4.1 B3K3A4_9BACI Histidine kinase internal region 371 e-100 B1D7W7.1 B1D7W7_9BACL Histidine kinase internal region 329 4e-88 B1RIM8.1 B1RIM8_CLOPE Sensor histidine kinase 179 5e-43 B1V666.1 B1V666_CLOPE Sensor histidine kinase 177 3e-42 B1BWL7.1 B1BWL7_CLOPE Sensor histidine kinase 177 3e-42 >B3K3A4.1 B3K3A4_9BACI Histidine kinase internal region Length = 594 Score = 371 bits (953), Expect = e-100, Method: Compositional matrix adjust. Identities = 211/601 (35%), Positives = 334/601 (55%), Gaps = 24/601 (3%) Query: 1 MGKLKWLWPSSMKNRLVLSILLFVLIPSAFLQIRNITQLETMMKDNISQQNAAQLNFLKN 60 + +++ L+P +K RL + +L +L+P L + N ++ET++++ ISQQ+ +QL + Sbjct: 2 LNRIRSLFPHKLKYRLFAAFVLVILLPFGILNLYNYQRIETLVQEKISQQSHSQLEQMYR 61 Query: 61 NIESLKFGVLGAMLQLERDPDLREQLGRTGEN--------MPEKNMFIKNELLLVKQRLM 112 +E ++ LE+D + L G+ M EK + N L Sbjct: 62 TLEDQLSVAFKTLIFLEQDSTVASVLTHPGQRQGLENKNLMEEKFKNLNNSFFLYNP--- 118 Query: 113 NAIVPVHLTLVDDKGEVYNTLEEGMAVPAVSGAELLQQPEFVKLRQGAEAYYWTVHEPDY 172 V+ T++D G Y + A+ +L P F + + +Y+W + +Y Sbjct: 119 ----SVYFTILDFYGNAYTSYSPR---EALDYRKLRDNPGFDRDQMEGVSYHWVSSDANY 171 Query: 173 LLANALPGSQLFSLFSKLQGTDGHTFAYLRISLDMKTWLNSITGGFQVKQTYYLLDGGGQ 232 +L + L SL++ ++ + RIS+D W S+ ++Q Y+L+ G+ Sbjct: 172 VLRDISTSPYLLSLYAYMETPRNKPYGMARISIDYSFWFQSVLKQSTLRQEYFLITSAGE 231 Query: 233 PILMGRNDRSAQALGGMLATFKSNP-ARYFTDDKDLFIFNGTYLPNMDWYLVSRFPLEAL 291 + ++ ++ G + A + P +YF D + N Y+ ++DWY+V+R PL L Sbjct: 232 NV--SQSILNSSLTGEVKARIAAEPRQKYFIDKASNTLVNYIYVESLDWYIVNRIPLTVL 289 Query: 292 SGNILAMKREVMLSFLVTCIIFAGIMYAIVSSTVRPLHNLQKKMSELVDKNLNVSIPERK 351 I +KR+ ++F + F + + I ++ RPL +LQ KM +V NL + +PE K Sbjct: 290 FNEIEELKRQYFMTFFLLTGAFLIMTFIIAATITRPLSHLQNKMKAVVRNNLKIRLPEHK 349 Query: 352 YKGELLRLARAFNLMTGDIRKLIERLQMEERQKEAIRFQMLMSQMNPHFLLNTLNTIKWN 411 ++GE+L L + FN M D+ LI+RL+ EERQKEA+ F ML++QMNPHFLLNTLNT+KW+ Sbjct: 350 FRGEILELTQTFNSMLNDMDVLIQRLKAEERQKEAVHFHMLLAQMNPHFLLNTLNTVKWS 409 Query: 412 ARNHGDMGTSEICQNLGKLLESGLNSDADLVFLKEEIELIRAYVYIQSFRYDHSFNVEYM 471 A HG+ + I +LGKLLE+ LN++ DLV LK+EIEL++AYV+IQ RY+H F+V + Sbjct: 410 AIRHGNEDITNITLSLGKLLEASLNTEKDLVHLKDEIELVQAYVHIQQVRYNHRFDVTFA 469 Query: 472 IGDGLEYALIPKFSLQPLVENAIYHGLVHM-KAGGKITILIAGAG-GRLRVEIGDNGQGL 529 + + YAL+PK LQPLVENAI HG+ + + G I I + G RL VEI DNG G+ Sbjct: 470 YDEDILYALVPKLCLQPLVENAIIHGIGPLSEQEGLIEITVTREGPNRLAVEIKDNGVGM 529 Query: 530 ERSGSASG-KRRKGIGLSNLRERIMLLYKGRGEXXXXXXXQGTVAVLDIPLLNSLPYDKE 588 E+S A G ++R GIGL+N++E + LL+K G +GT IPLL S PY + Sbjct: 530 EQSRQAGGMRKRPGIGLNNVQELLRLLFKEEGSMEIISSERGTRIRFSIPLLISTPYQND 589 Query: 589 E 589 Sbjct: 590 H 590 >B1D7W7.1 B1D7W7_9BACL Histidine kinase internal region Length = 603 Score = 329 bits (844), Expect = 4e-88, Method: Compositional matrix adjust. Identities = 214/596 (35%), Positives = 331/596 (55%), Gaps = 19/596 (3%) Query: 4 LKWLWPSSMKNRLVLSILLFVLIPSAFLQIRNITQLETMMKDNISQQNAAQLNFLKNNIE 63 + L P++ KNR++LS+L+F+L+P A L + N + E +++ N S +N QL LK ++ Sbjct: 6 FRLLTPATFKNRILLSLLIFLLVPIALLFLYNFRETEELLQRNASDKNIEQLEGLKTDLV 65 Query: 64 SLKFGVLGAMLQLERDPDLREQLGRTGE-NMPEKNMFIKNELLLVKQRLMNAIVPVHLTL 122 L V+ + LE+D LR+ + + + + + ++N+ ++ V+ TL Sbjct: 66 DLMSLVMKTGMLLEQDSVLRQVMQKPEQYDAINRKKIVENKFAGIENSFFLTGATVYYTL 125 Query: 123 VDDKGEVYN--TLEEGMAVPAVSGAELLQQPEFVKLRQGAEAYYWTVHEPDYLLANALPG 180 +D KG Y T E + +S +++ + R+G + Y W ++ + + G Sbjct: 126 IDLKGNAYTSYTPENSLNYEEISSEAWVRELK----REGGQRYIWRTNDQSTEI-REVKG 180 Query: 181 SQLFSLFSKLQGTDGHTFAYLRISLDMKTWLNSITGGFQVKQTYYLLDGGGQPILMGRND 240 +++ SLF L+ FAY R S+D + W T G + Y+LLD GG IL + Sbjct: 181 NRMLSLFELLRDDGLKPFAYGRFSIDYEAWFAEKTQGSGGEGAYFLLDAGGNTILQSSPE 240 Query: 241 RSAQALGGMLATFKSNPARYFTDDKDLFIFNG----TY--LPNMDWYLVSRFPLEALSGN 294 S + A+ S +D I N TY + +D YLV + PL L Sbjct: 241 ESVPP--AVAASIASAGRSGESDASSTSILNNRIMYTYSNVQELDGYLVKKVPLSLLFNE 298 Query: 295 ILAMKREVMLSFLVTCIIFAGIMYAIVSSTVRPLHNLQKKMSELVDKNLNVSIPERKYKG 354 + K+ ++ I+F ++Y I S+ PL LQ+KM V NL +PE+ +G Sbjct: 299 VDKQKKRSFALYITILILFMLMIYFISSTVTGPLKLLQRKMETTVKSNLKAKLPEQG-RG 357 Query: 355 ELLRLARAFNLMTGDIRKLIERLQMEERQKEAIRFQMLMSQMNPHFLLNTLNTIKWNARN 414 E+L L R+FN M DI L+ERL++EERQK+ +RFQ+L+ QMNPHFLLNTLNTIK A + Sbjct: 358 EILALTRSFNSMITDINGLLERLKLEERQKQYVRFQVLLGQMNPHFLLNTLNTIKSIALD 417 Query: 415 HGDMGTSEICQNLGKLLESGLNSDADLVFLKEEIELIRAYVYIQSFRYDHSFNVEYMIGD 474 + +IC LGK+LE+ LN++ADL+ LKEEI LI +Y+ IQ R+ H V+Y + Sbjct: 418 KDEDDIYDICVALGKILETTLNTEADLILLKEEIVLIESYMDIQRKRFGHGIEVQYEVEG 477 Query: 475 GLEYALIPKFSLQPLVENAIYHGLVHMKAGGKITILIAGAGGRLRVEIGDNGQGLERS-G 533 LE+ALIPKFSLQPLVEN++ HG + GG+I I A G +L +E+ DNG G+E++ Sbjct: 478 ELEFALIPKFSLQPLVENSLLHGFGQSQRGGRIVIRAASRGKQLILEVIDNGVGIEKAKN 537 Query: 534 SASGKRRKGIGLSNLRERIMLLYKGRGE-XXXXXXXQGTVAVLDIPLLNSLPYDKE 588 + S ++RK IG+ NLRE + L++K + +GT ++ PLL S PY +E Sbjct: 538 NQSARKRKSIGIQNLRESLELMFKNQPSGLQVESSEEGTRVTMNCPLLLSKPYTEE 593 >B1RIM8.1 B1RIM8_CLOPE Sensor histidine kinase Length = 583 Score = 179 bits (455), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 156/588 (26%), Positives = 282/588 (47%), Gaps = 40/588 (6%) Query: 6 WLWPSSMKNRLVLSILLFVLIPSAFLQIRNITQLETMMKDNISQQNAAQLNFLKNNIESL 65 +L +S+KNRL+ S + ++ S+ L I + +K+N + L+ + +I Sbjct: 18 FLRKTSIKNRLIASFSVGIIFCSSILGILLYKKATNALKNNAINYSENMLSIMSEDIYKN 77 Query: 66 KFGVLGAMLQLERDPDLREQL-GRTGENMPEKNMFIKNELLLVKQRLMNAIVPVHLTLVD 124 K + A ++L + ++ L + EKN F+K MN + L+L+ Sbjct: 78 KEFLERASIELSMNEEIANNLINYKFMDGKEKNEFLK---------YMNDYLSKKLSLLP 128 Query: 125 DKGEVYNTLEEGMAVPAVSGAELLQQPEFVKLRQGAE-AYYW--TVHEPDYLLANALPGS 181 + EV + + V + G + ++ + + +E +W T+ + + P Sbjct: 129 NLAEV-EIISKDYEVTYMQGFKYFKREDIERYADESENGLFWFSTILNNEPHICIVTPVK 187 Query: 182 QLFSLFSKLQGTDGHTFAYLRISLDMKTW-LNSITGGFQVKQTYYLLDGGGQPILMGRND 240 Q S+ G+ F ++ + ++ L +I G ++ +++D I+ N Sbjct: 188 QDNSIL-------GYIFMAIKSEVFASSFSLFNIGKGSEI----FIIDEKNNIIISENNL 236 Query: 241 RSA-----QALGGMLATFKS-NPARYFTDDKDLFIFNGTYLPNMDWYLVSRFPLEALSGN 294 S+ L L S N AR + ++ L +WY+ S P + ++ + Sbjct: 237 NSSFILEEPDLNKFLKNKDSKNTARSIMVNGKNYVATYRKLKGFNWYIASMTPYDFINAD 296 Query: 295 ILAMKREVM---LSFLVTCIIFAGIMYAIVSSTVRPLHNLQKKMSELVDKNLNVSIPERK 351 I ++++E+ L F + +IF+ +Y SS PL+NL KM + + +L V + + Sbjct: 297 IQSLRKEMTIIGLLFTLVVLIFSYFLY---SSIKVPLYNLLNKMKRVSEGDLKVLVNDT- 352 Query: 352 YKGELLRLARAFNLMTGDIRKLIERLQMEERQKEAIRFQMLMSQMNPHFLLNTLNTIKWN 411 Y+ E+ ++ F+ M + +LIE+ +++E +K + +ML +Q+NPHFL NTLN++KW Sbjct: 353 YEDEIGVISDNFDSMLKRVNELIEKTKLQEVEKRDLEIRMLQAQINPHFLFNTLNSLKWT 412 Query: 412 ARNHGDMGTSEICQNLGKLLESGLNSDADLVFLKEEIELIRAYVYIQSFRYDHSFNVEYM 471 A + D SE +L +LL + + +LV ++EE+E I+ YV IQ RY +SF+V+Y Sbjct: 413 ALMNQDYTVSEGLSSLAELLRNTIIDKNELVTIREELENIKNYVVIQKIRYGNSFDVQYE 472 Query: 472 IGDGLEYALIPKFSLQPLVENAIYHGLVHMKAGGKITILIAGAGGRLRVEIGDNGQGLER 531 + + L + KF LQP+VEN+I HG+ K KI I I + + I DNG+G Sbjct: 473 VDELLLENKVIKFILQPIVENSIIHGIDENKENQKIIIKIMSEEENILISIKDNGKGFNS 532 Query: 532 SGSASGKRRKGIGLSNLRERIMLLYK-GRGEXXXXXXXQGTVAVLDIP 578 + GIG +N+ ERI L + G G +GT+ + IP Sbjct: 533 KEKVKDNKLSGIGWNNVDERIKLTFGLGYGTTIYSEVNKGTIVKIVIP 580 >B1V666.1 B1V666_CLOPE Sensor histidine kinase Length = 514 Score = 177 bits (449), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 106/313 (33%), Positives = 174/313 (55%), Gaps = 10/313 (3%) Query: 272 GTY--LPNMDWYLVSRFPLEALSGNILAMKREVM---LSFLVTCIIFAGIMYAIVSSTVR 326 TY L +WY+ S P + ++ +I ++++E+ L F + +IF+ +Y SS Sbjct: 203 ATYRKLKGFNWYIASMTPYDFINADIQSLRKEMTIIGLLFTLVVLIFSYFLY---SSIKV 259 Query: 327 PLHNLQKKMSELVDKNLNVSIPERKYKGELLRLARAFNLMTGDIRKLIERLQMEERQKEA 386 PL+NL KM + + +L V + + Y+ E+ ++ F+ M + +LIE+ +++E +K Sbjct: 260 PLYNLLNKMKRVSEGDLKVLVNDT-YEDEIGVISDNFDSMLKRVNELIEKTKLQEVEKRD 318 Query: 387 IRFQMLMSQMNPHFLLNTLNTIKWNARNHGDMGTSEICQNLGKLLESGLNSDADLVFLKE 446 + +ML +Q+NPHFL NTLN++KW A + D SE +L +LL + + +LV ++E Sbjct: 319 LEIRMLQAQINPHFLFNTLNSLKWTALMNQDYTVSEGLSSLAELLRNTIIDKNELVTIRE 378 Query: 447 EIELIRAYVYIQSFRYDHSFNVEYMIGDGLEYALIPKFSLQPLVENAIYHGLVHMKAGGK 506 E+E I+ YV IQ RY +SF+V+Y + + L + KF LQP+VEN+I HG+ K K Sbjct: 379 ELENIKNYVVIQKIRYGNSFDVQYEVDELLLENKVIKFILQPIVENSIIHGIDENKENQK 438 Query: 507 ITILIAGAGGRLRVEIGDNGQGLERSGSASGKRRKGIGLSNLRERIMLLYK-GRGEXXXX 565 I I I + + I DNG+G + GIG +N+ ERI L + G G Sbjct: 439 IIIKIMSEEENILISIKDNGKGFNSKEKVKDNKLSGIGWNNVDERIKLTFGLGYGTTIYS 498 Query: 566 XXXQGTVAVLDIP 578 +GT+ + IP Sbjct: 499 EVNKGTIVKIVIP 511 >B1BWL7.1 B1BWL7_CLOPE Sensor histidine kinase Length = 514 Score = 177 bits (449), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 106/313 (33%), Positives = 174/313 (55%), Gaps = 10/313 (3%) Query: 272 GTY--LPNMDWYLVSRFPLEALSGNILAMKREVM---LSFLVTCIIFAGIMYAIVSSTVR 326 TY L +WY+ S P + ++ +I ++++E+ L F + +IF+ +Y SS Sbjct: 203 ATYRKLKGFNWYIASMTPYDFINADIQSLRKEMTIIGLLFTLVVLIFSYFLY---SSIKV 259 Query: 327 PLHNLQKKMSELVDKNLNVSIPERKYKGELLRLARAFNLMTGDIRKLIERLQMEERQKEA 386 PL+NL KM + + +L V + + Y+ E+ ++ F+ M + +LIE+ +++E +K Sbjct: 260 PLYNLLNKMKRVSEGDLKVLVNDT-YEDEIGVISDNFDSMLKRVNELIEKTKLQEVEKRD 318 Query: 387 IRFQMLMSQMNPHFLLNTLNTIKWNARNHGDMGTSEICQNLGKLLESGLNSDADLVFLKE 446 + +ML +Q+NPHFL NTLN++KW A + D SE +L +LL + + +LV ++E Sbjct: 319 LEIRMLQAQINPHFLFNTLNSLKWTALMNQDYTVSEGLSSLAELLRNTIIDKNELVTIRE 378 Query: 447 EIELIRAYVYIQSFRYDHSFNVEYMIGDGLEYALIPKFSLQPLVENAIYHGLVHMKAGGK 506 E+E I+ YV IQ RY +SF+V+Y + + L + KF LQP+VEN+I HG+ K K Sbjct: 379 ELENIKNYVVIQKIRYGNSFDVQYEVDELLLENKVIKFILQPIVENSIIHGIDENKENQK 438 Query: 507 ITILIAGAGGRLRVEIGDNGQGLERSGSASGKRRKGIGLSNLRERIMLLYK-GRGEXXXX 565 I I I + + I DNG+G + GIG +N+ ERI L + G G Sbjct: 439 IIIKIMSEEENILISIKDNGKGFNSKEKVKDNKLSGIGWNNVDERIKLTFGLGYGTTIYS 498 Query: 566 XXXQGTVAVLDIP 578 +GT+ + IP Sbjct: 499 EVNKGTIVKIVIP 511 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.138 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,483,261,530 Number of extensions: 150648060 Number of successful extensions: 397039 Number of sequences better than 1.0e-05: 1987 Number of HSP's gapped: 394723 Number of HSP's successfully gapped: 1987 Length of query: 599 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 457 Effective length of database: 1,722,912,073 Effective search space: 787370817361 Effective search space used: 787370817361 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)