BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0493.0022.p (570 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I0Y1.1 B8I0Y1_CLOCE Putative sensor with HAMP domain 726 0.0 A7VQ29.1 A7VQ29_9CLOT Putative uncharacterized protein 298 1e-78 A7VR08.1 A7VR08_9CLOT Putative uncharacterized protein 275 1e-71 B0NF52.1 B0NF52_EUBSP Putative uncharacterized protein 220 3e-55 C0FTY4.1 C0FTY4_9FIRM Putative uncharacterized protein 219 8e-55 >B8I0Y1.1 B8I0Y1_CLOCE Putative sensor with HAMP domain Length = 600 Score = 726 bits (1873), Expect = 0.0, Method: Compositional matrix adjust. Identities = 341/567 (60%), Positives = 453/567 (79%), Gaps = 1/567 (0%) Query: 5 GCYFYWNISQILTKNANDNLSLLIRQTNDNIEKSFQIIDNTSLHFLANKTIRTWSIEDVS 64 G YFYWN++ +LTKNANDNL LI+Q N NIE SF+IID TSLHFL+NK++R+W+++D S Sbjct: 34 GFYFYWNMASVLTKNANDNLVNLIQQANGNIENSFKIIDTTSLHFLSNKSMRSWTLDDTS 93 Query: 65 LGDDYYKKFLNKSEMEEDLKYSLMFNNAWNISLLSTAYVFFDKDNYISVLKSQPNIEQIN 124 D+Y F+NK +EEDLKYSLMFNNAW+++L+STAYVF ++D Y S+ KS PNI+ IN Sbjct: 94 FDGDFYSIFINKRHIEEDLKYSLMFNNAWDMNLISTAYVFLNEDTYCSIFKSTPNIQLIN 153 Query: 125 KNNLAVFHSVNG-RVRGKEIITPSYEDRTLYFTRIVSNINLPQQRLVLIFGTDEADLADQ 183 N++ +F ++G ++RGK +I PS D+T+YFTRIV+NI+ P+QRLV+IFGT+E + + Sbjct: 154 DNHINIFKRISGSKIRGKTMIPPSLNDKTIYFTRIVTNISNPKQRLVMIFGTEEEEFYKK 213 Query: 184 YSGLLAFPGAMAYIIDNRGAIYSSADKQELGSIVSPAVFALKDNAEVREVKLNHESYLTV 243 YS LL+F G+M YI D +G IYSS+ + LG+ V ++ L+++ V EV + + +YL Sbjct: 214 YSELLSFEGSMVYITDEKGIIYSSSQRDNLGNNVPSSILNLRNDTGVSEVDIGNVTYLIA 273 Query: 244 SRSIGTTGLTFIAGIPKKQVLSKLSESMRNYIRIIALIAFVSLAAGVLLSLRFTRVIRDL 303 R I TGL FIAGIPK+QVL+KLS+SM+NYI I A+I F+S+ +G+++SLRFTR +RD+ Sbjct: 274 HRKISDTGLDFIAGIPKEQVLAKLSDSMKNYIVITAIIVFISVFSGIIISLRFTRFVRDM 333 Query: 304 LRSIHKVKKGDYNVRMPAYKNVELNQLSTTFNRMTEEINYLIKEVYEKHLLIKESEIKFL 363 L I++VK GDY+V+MP YK+ EL +S TFN MT EI YLI +VYEK LLIKE+E KFL Sbjct: 334 LSVINRVKVGDYDVKMPYYKDNELKLVSNTFNNMTYEIKYLINQVYEKQLLIKETEFKFL 393 Query: 364 QAQINPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAGIYSNSLAKVPIRQELDVI 423 Q+Q+NPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAGIYSNS AK+PIRQEL+ I Sbjct: 394 QSQMNPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAGIYSNSQAKIPIRQELEFI 453 Query: 424 QFYLYLQKERFEDKIEYTIHIEDETILDLLLPKLSVEPLVENAVVHGVEKKLGKGIIHIR 483 FYLYLQK RF DK+EY I++ DE+IL+ +LPKLS+EPL+ENAVVHG+E+K+GKG I + Sbjct: 454 DFYLYLQKMRFGDKLEYKIYVSDESILNFVLPKLSIEPLIENAVVHGLEEKVGKGTIELN 513 Query: 484 IYRRNESVYFEITDNGNGFEVVPRNWSNFESITIRKQGHNNIGLINTQKRVKLIYGEPYG 543 I R NES++F +TD+G GF+ N + ++I +RK+GHN+IGL+NT KR+KL+YG+PYG Sbjct: 514 IRRENESIFFVVTDDGAGFKTDKINLDDNDTINMRKKGHNSIGLMNTHKRIKLMYGDPYG 573 Query: 544 IEVESEFGAGAKVTLHIPADQGELSHV 570 +++ES GAKVT+HIP D+ E +V Sbjct: 574 VQIESRTNIGAKVTVHIPVDRSETDNV 600 >A7VQ29.1 A7VQ29_9CLOT Putative uncharacterized protein Length = 602 Score = 298 bits (763), Expect = 1e-78, Method: Compositional matrix adjust. Identities = 170/567 (29%), Positives = 307/567 (54%), Gaps = 21/567 (3%) Query: 8 FYWNISQILTKNANDNLSLLIRQTNDNIEKSFQIIDNTSLHFLANKTIRTWSIEDVSLGD 67 F++++ +I +NL L DNI S ID T+ + + +R + E +L + Sbjct: 37 FFFSVKKINEDIVYNNLESLQLAVEDNISSSLSAIDKTAKNIILGSNVRQFLREGANLAE 96 Query: 68 -DYYKKFLNKSEMEEDLKYSLMFNNAWNISLLSTAYVFFDKDNYISV-------LKSQPN 119 D K L + +E ++ ++FN+ L+ + + D+ N LK P+ Sbjct: 97 MDESGKVLLRQSIEREISNQMLFNSILEEGLIESVNFYLDEHNIAFFSRNGSLDLKDSPS 156 Query: 120 IEQINKNNLAVFHSVNGRVRG-KEIITPSYEDRTLYFTRIVSNINLPQQRLVLIFGTDEA 178 + Q V+ ++ + +I + + D L+F +S+++ + + LI + Sbjct: 157 VRQ-------VYRTIQQKSSANPQIFSSTLNDPFLHFAYRISSLDQSSRSVYLIITINRE 209 Query: 179 DLADQYSGLLAFPGAMAYIIDNRGAIYSSADKQELGSIVSPAVFALKDNAEVREVKLNHE 238 L + + + ++ Y+ D +G + S ++ G+ + + ++ + + Sbjct: 210 GLLAKCQSITDYENSVVYLADQKGTVILSNQQENEGAPLPDGIDGNYTQGKITHLDFDGT 269 Query: 239 SYLTVSRSIGTTGLTFIAGIPKKQVLSKLSESMRNYIRIIALIAFVSLAAGVLLSLRFTR 298 +L S+ + +P++ + L E+MR+Y+ + +++ + +A VLLSLR T Sbjct: 270 KHLYFSQWLNDKDFFLAVMMPEELFVRSLYEAMRDYLFLSVVVSLIIMALIVLLSLRMTA 329 Query: 299 VIRDLLRSIHKVKKGDYNVRMPAYKNVELNQLSTTFNRMTEEINYLIKEVYEKHLLIKES 358 D + K KGD V++P Y++ +LN +S TFN+MTE IN+L+++ Y+K LLI++ Sbjct: 330 FTHDFTEGLQKFGKGDLTVKLPPYRDADLNHISNTFNQMTERINFLVEDGYKKQLLIQQM 389 Query: 359 EIKFLQAQINPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAGIYSNSLAKVPIRQ 418 +I+FLQ+Q+NPHFLFNTL TI +AK+S D+ +++MV +LT LLQA +++ + K+ + Q Sbjct: 390 DIEFLQSQMNPHFLFNTLFTISTRAKMSGDDLLFEMVQALTRLLQASLHTKNDIKITVAQ 449 Query: 419 ELDVIQFYLYLQKERFEDKIEYTIHIEDETILDLLLPKLSVEPLVENAVVHGVEKKLGKG 478 EL+ I YLY+QK R+ K+EY + IL LL+P+L ++PLVENAVVHG+E G Sbjct: 450 ELEYINAYLYIQKVRYGSKLEYAVSTGSPEILTLLIPRLCIQPLVENAVVHGIEPLSATG 509 Query: 479 IIHIRIYRRNESVYFEITDNGNGFEVVPRNWSNFESITIRKQGHNNIGLINTQKRVKLIY 538 I I + + ++++ +TDNG GF+ P + + N+I L N Q+R++LIY Sbjct: 510 HIDIAMELKEDALWITVTDNGVGFD--PAEAPDGSA---PPSHSNHIALQNLQERIRLIY 564 Query: 539 GEPYGIEVESEFGAGAKVTLHIPADQG 565 G YG+ ++S G G + + +P D+G Sbjct: 565 GGAYGVTIDSAPGRGCRAVVILPVDKG 591 >A7VR08.1 A7VR08_9CLOT Putative uncharacterized protein Length = 570 Score = 275 bits (703), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 167/575 (29%), Positives = 300/575 (52%), Gaps = 10/575 (1%) Query: 1 MTFAGCYFYWNISQILTKNANDNLSLLIRQTNDNIEKSFQIIDNTSLHFLANKTIRTWSI 60 M G Y + +N + + + +T NI++SF I NT L T+ W Sbjct: 1 MLVIGGYLVMVMYSKAYENTYEKMQIYTDKTVQNIDQSFSFITNTGLAVATGGTVGHWIN 60 Query: 61 EDVSLGDDYYKKFLNKSEMEEDLKYSLMFNNAWNISLLSTAYVFFDKDNYISVLKSQPNI 120 DD + N + ++ + + L ++NAW + +S + + D + V +Q Sbjct: 61 NTRLFDDDSSAYYTNINNLKNETNHVLTYSNAWKTNYISYICILLNDDPLLYVSANQITP 120 Query: 121 EQINKNNLAVFHSVNGRVRGKEI--ITPSYEDRTLYFTR-IVSNINLPQQRLVLIFGTDE 177 I ++ ++ + + I I P ++ ++ R + + N P L ++ T+E Sbjct: 121 NTIYQSAVSANQILKENQEQQFIGDIPPVVDNNQIFHVRRMQRDFNSPDS-LSIVIATNE 179 Query: 178 ADLADQYSGLLAFPGAMAYIIDNRGAIYSSADKQELGSIVSPAVFALKDNAEVREVKLNH 237 L YS G Y++D G I+SS+++ ++G +F + + + Sbjct: 180 KALYQDYSRYYGGEGNSTYLLDEEGYIFSSSERDQVGEKFEEDIFQEIKSGSNGNFRRDG 239 Query: 238 ESYLTVSRSIGTTGLTFIAGIPKKQVLSKLSESMRNYIRIIALIAFVSLAAGVLLSLRFT 297 ++YL S+ + + LT + +P++ ++ + E I ++ V LA G ++S + T Sbjct: 240 KNYLYFSKPLSSNSLTLLNVVPEQVIIDQTLEGTPFLFVIAGILCIVLLAVGYIVSFKST 299 Query: 298 RVIRDLLRSIHKVKKGDYNVRMPAYKNVELNQLSTTFNRMTEEINYLIKEVYEKHLLIKE 357 I+DL+ +++VKK +Y+V+MP Y N ++ L FN MT + LI + Y+ ++ +E Sbjct: 300 SFIKDLVICMNEVKKKNYDVKMPHYSNSAVDALGMYFNDMTAAMKTLINDTYKAKIMRQE 359 Query: 358 SEIKFLQAQINPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAGIYSNSLAKVPIR 417 E++F+Q Q+NPHFLFN L T+ KAK+ DETVY+M+ SL+ LL+A +YS + Sbjct: 360 MELEFIQQQMNPHFLFNVLSTVQIKAKMCGDETVYQMLASLSGLLRASLYSGKSMMTSLS 419 Query: 418 QELDVIQFYLYLQKERFEDKIEYTIHIEDETILDLLLPKLSVEPLVENAVVHGVEKKLGK 477 +E+ +FYLYLQK+R++D+++Y I +E + + +P+L++EP+VEN+V+HG+E + + Sbjct: 420 EEVQYAEFYLYLQKQRYQDRLDYHISME-PGLERVRIPRLTIEPIVENSVLHGMEGDIER 478 Query: 478 GIIHIRIYRRNESVYFEITDNGNGFEVVPRNWSNFESITIRKQG-HNNIGLINTQKRVKL 536 + + I + + + I DNG GF+ + S E + +G +GL NT R+ L Sbjct: 479 VCVELAITKEEKCLKIRIADNGRGFDTKQLDLSGGE---VSLEGTREKVGLKNTHNRLTL 535 Query: 537 IYGEPYGIEVESEFGAGAKVTLHIPAD-QGELSHV 570 +YGE YG+ + S G G V + IP D +GE V Sbjct: 536 LYGEAYGLRIHSAPGEGTVVEIVIPLDRKGESDEV 570 >B0NF52.1 B0NF52_EUBSP Putative uncharacterized protein Length = 591 Score = 220 bits (561), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 163/586 (27%), Positives = 296/586 (50%), Gaps = 49/586 (8%) Query: 3 FAGCYFYWNISQILTKNANDNLSLLIRQTNDNIEKSFQIIDNTSLHFLANKTIRTWSIED 62 G F ++S ++ K + +L +++ +NIEK + + L+ L + + + D Sbjct: 31 LCGVLFICSVSWVIGKYIDHDLDFFLKEAGENIEKRMEYMTEV-LNELRSSELLMEYLRD 89 Query: 63 VSLGDDYYKKFLNKSEMEEDLKYSLMFNNAWN-----ISLLSTAYVFFDKDNYIS----- 112 G + Y + ++ + ++ NN+ N + L+ Y+F + YI+ Sbjct: 90 ---GGNTY----SLEKVRQAFSEAVDINNSSNRGDEGMPLVDCVYLFRNSGEYITDFYYA 142 Query: 113 -VLKSQPNIEQINKNNLAVFHSVNGRVRGKEIITPSYED-RTLYFTRIVSNINLPQQRLV 170 V Q +QI N V+ G E T Y D ++LY + N +L +Q Sbjct: 143 IVPGDQEKSDQIIANVWKVYRDTRDNEIGFE--TYCYRDGKSLYLACPILNDSLEEQG-S 199 Query: 171 LIFGTDEADLADQYSGLLAFPGAMAYIIDNRGAIYSSADKQELGSIVSPAVFALKDNAEV 230 L+F + + + + + G + I +G I + K KD EV Sbjct: 200 LVFRLNIKTIYSLMNQVGDYRGGVCAIYTKKGNILETYPKN--------VDLLGKDWKEV 251 Query: 231 RE-----VKLNHESYLTVSRSIGTTGLTFIAGIPKKQVLSKLSESMRNYIRIIALIAFVS 285 K+ E Y + + L GIP+ + L +S+ Y+ I I Sbjct: 252 SHNTPYIGKIGEEKYRLYNHEL-CMDLRVAIGIPENYAIKILYDSIDIYVVGIIAIIIAG 310 Query: 286 LAAGVLLSLRFTRVIRDLLRSIHKVKKGDYNVRMPAYKNVELNQLSTTFNRMTEEINYLI 345 + + + +++ T I ++ + V + ++ ++P Y + E + +S FN+MT+EI+YL+ Sbjct: 311 ILSFGVFTIKMTSPIEEVNEKLKLVGQRNFQAKLPDYDSKEFHAISCGFNQMTKEIDYLV 370 Query: 346 KEVYEKHLLIKESEIKFLQAQINPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAG 405 EVYEK +LIKE E+KFLQ Q+NPHF+FN L + +A++ + + K +++ ++L+QA Sbjct: 371 NEVYEKQILIKEMELKFLQTQMNPHFMFNVLNALALQAQIDGNRELSKKISTFSQLIQAK 430 Query: 406 IYSNSLAKVPIRQELDVIQFYLYLQKERFEDKIEYTIHIEDETILDLLLPKLSVEPLVEN 465 IY + KV I+QEL+ +++YL +Q+ R+E+ + Y+I +E + + + +PKL ++ +VEN Sbjct: 431 IYRSDTEKVQIKQELEYVKYYLEIQEFRYENNLTYSIQME-KGVEEYYIPKLCIQLVVEN 489 Query: 466 AVVHGVEKKLGKGIIHIRIYRRNESVYFEITDNGNGFEV-----VPRNWSNFESITIRKQ 520 A+VHG+E KLGKG + + I + +E + + DNG GF++ +P + + Sbjct: 490 AIVHGLEPKLGKGNVEVDIRKEDEHICICVNDNGIGFDMDGEVLLPLKAKEADKV----- 544 Query: 521 GHNNIGLINTQKRVKLIYGEPYGIEVESEFGAGAKVTLHIPADQGE 566 HN +GL N +KL+YG +GI + S+ G G +VT+++P D GE Sbjct: 545 -HNRVGLNNVNNIIKLMYGNEFGIHIFSKKGKGVRVTIYLPTDIGE 589 >C0FTY4.1 C0FTY4_9FIRM Putative uncharacterized protein Length = 618 Score = 219 bits (557), Expect = 8e-55, Method: Compositional matrix adjust. Identities = 118/341 (34%), Positives = 197/341 (57%), Gaps = 16/341 (4%) Query: 243 VSRSIGTTGLTFIAGIPKKQVLSKLSESMRNYIRIIALIAFVSLAAGVLLSLRFTRVIRD 302 VS GL I + + +L+ L ++ ++ + ++ ++ +S RFT+ Sbjct: 274 VSADASGFGLRTIIAVGQNNILAILRPTLIIFLVGLVIVLILTFLVSYGISYRFTKPAAR 333 Query: 303 LLRSIHKVKKGDYNVRMPAYKNVELNQLSTTFNRMTEEINYLIKEVYEKHLLIKESEIKF 362 ++ +I + + NVRM E + + FN M + I YLI EVYEK LL +S++K+ Sbjct: 334 MIANIRAFGRKELNVRMEDSSIQEFHDIGQVFNEMADRIEYLITEVYEKQLLATQSQVKY 393 Query: 363 LQAQINPHFLFNTLITIGYKAKLSKDETVYKMVTSLTELLQAGIYSNSLAKVPIRQELDV 422 LQ+Q+NPHF FN L + KAK++ +E +Y+ + + ++L+Q I+ K+ +R+EL++ Sbjct: 394 LQSQLNPHFQFNILAMLSLKAKMAGNEELYESLNAFSKLMQGKIFREKEIKIKVREELEI 453 Query: 423 IQFYLYLQKERFEDKIEYTIHIEDETILDLLLPKLSVEPLVENAVVHGVEKKLGKGIIHI 482 +QFYL+LQKER++DK+ Y I+IEDE I + L+P+L +EPLVENAV HG+E K GII + Sbjct: 454 VQFYLFLQKERYQDKLTYEINIEDEQIKENLIPRLLIEPLVENAVSHGLEPKKESGIIRV 513 Query: 483 RIYRRN---------------ESVYFEITDNGNGFEVVPRNWSNFESI-TIRKQGHNNIG 526 +Y N + ++ + DNG G + N + E + K H + G Sbjct: 514 CMYEENFIEENDEIKKQKKTSKILHIIVEDNGVGIDYEKMNEKSTEEVQQPEKIDHTHTG 573 Query: 527 LINTQKRVKLIYGEPYGIEVESEFGAGAKVTLHIPADQGEL 567 NT+K ++++YGE Y + SE G G K+ + +PA++GE+ Sbjct: 574 FENTRKMLQILYGENYKFNIWSEKGKGTKIEIILPAERGEI 614 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.382 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,209,308,357 Number of extensions: 136169695 Number of successful extensions: 407818 Number of sequences better than 1.0e-05: 2102 Number of HSP's gapped: 403876 Number of HSP's successfully gapped: 2104 Length of query: 570 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 429 Effective length of database: 1,732,333,088 Effective search space: 743170894752 Effective search space used: 743170894752 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)