BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0493.0010.p (281 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C3GW79.1 C3GW79_BACTU Sensory transduction protein kinase 317 8e-85 A7Z0X1.1 A7Z0X1_BACA2 Sensory transduction protein kinase EC=2.7... 235 3e-60 B1KTH3.1 B1KTH3_CLOBM Sensor histidine kinase 197 7e-49 A6M051.1 A6M051_CLOB8 Integral membrane sensor signal transducti... 173 1e-41 C4IBW5.1 C4IBW5_CLOBU Integral membrane sensor signal transducti... 172 3e-41 >C3GW79.1 C3GW79_BACTU Sensory transduction protein kinase Length = 385 Score = 317 bits (812), Expect = 8e-85, Method: Compositional matrix adjust. Identities = 158/272 (58%), Positives = 202/272 (74%), Gaps = 1/272 (0%) Query: 1 LCLHFSIFTASLIADHTTLRDXXXXXXXXXXXXXXFRNVLIEKARTQELNQELQIANTTL 60 L LHF I+ +L T ++D FRN+L+EK + Q LNQEL++AN TL Sbjct: 115 LGLHFIIYLIALKIADTNIKDILTSYLVIMSILYLFRNILLEKEKIQILNQELKVANNTL 174 Query: 61 QEYSNKIQELTISQERTRIAQELHDSLGHYLIALNMNLEYASTIVDVETDKAKLAIQKSQ 120 QEYS KI+ELTIS+ERTRIAQELHDSLGHYL+AL MNLEYA+ +VD+E +K K I+KSQ Sbjct: 175 QEYSEKIKELTISKERTRIAQELHDSLGHYLVALTMNLEYAAKVVDIEPEKVKSVIKKSQ 234 Query: 121 QLSKECIVNLRKTVVLLGDERASKELLQSLHEIFDNFLETNKIQFELNMDEDIEYVDSDI 180 LS++CI+NLR+ V LL A K L +S+ EIF+NF ET+ I+FEL + E +E+V+ DI Sbjct: 235 NLSRDCILNLRQAVALLNANPAQKGLRKSIEEIFENFRETSGIEFELEIKEAVEFVNPDI 294 Query: 181 KNCIYKTVQESITNGIKHGQATHFSIAIHKYSDHISLLVHNNGADCKEIIKSKGIQGIEN 240 KNC+YKTVQE+ITNGIKHG A FSI IHK D I L++ NNGA C I+KS GI GIE+ Sbjct: 295 KNCLYKTVQEAITNGIKHGNAEKFSIKIHKNYDQILLIIMNNGARCTNIVKSNGINGIES 354 Query: 241 RILALGGKVVFYSGESSGFRVEANIPKITVDF 272 R++ALGG+V FYS + SGF V+A+IP+I +DF Sbjct: 355 RVIALGGEVHFYSDDYSGFIVKASIPEI-IDF 385 >A7Z0X1.1 A7Z0X1_BACA2 Sensory transduction protein kinase EC=2.7.3.- Length = 376 Score = 235 bits (599), Expect = 3e-60, Method: Compositional matrix adjust. Identities = 117/231 (50%), Positives = 159/231 (68%) Query: 36 FRNVLIEKARTQELNQELQIANTTLQEYSNKIQELTISQERTRIAQELHDSLGHYLIALN 95 +R L EK++ + LN+EL+IAN TL+EYS++I+EL +++ERTRIAQELHDSLGHYL AL Sbjct: 142 YRRNLQEKSKVELLNRELKIANDTLKEYSDRIEELAVTKERTRIAQELHDSLGHYLAALK 201 Query: 96 MNLEYASTIVDVETDKAKLAIQKSQQLSKECIVNLRKTVVLLGDERASKELLQSLHEIFD 155 MNLE+A + DK K I K+ L+KE I+ LR+ V+LL + Q L +IF Sbjct: 202 MNLEFAGKTAGHQPDKVKQIIHKAHDLTKESILKLRQAVMLLQGSLPGRGFEQELRDIFS 261 Query: 156 NFLETNKIQFELNMDEDIEYVDSDIKNCIYKTVQESITNGIKHGQATHFSIAIHKYSDHI 215 +F E I+FEL MD IE D+K+C+Y++VQE+ITN IKHG A++ S+ I K + I Sbjct: 262 HFQEAGGIRFELEMDAAIEAEQPDVKHCLYQSVQETITNAIKHGHASYVSVRIQKNRNMI 321 Query: 216 SLLVHNNGADCKEIIKSKGIQGIENRILALGGKVVFYSGESSGFRVEANIP 266 +HNNG+ C IIKS G++GIE R ALGG+ VF SG+ +GF V+ IP Sbjct: 322 LAHIHNNGSACGTIIKSNGLKGIEKRAAALGGEAVFSSGKETGFDVKIRIP 372 >B1KTH3.1 B1KTH3_CLOBM Sensor histidine kinase Length = 344 Score = 197 bits (502), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 103/231 (44%), Positives = 157/231 (67%) Query: 41 IEKARTQELNQELQIANTTLQEYSNKIQELTISQERTRIAQELHDSLGHYLIALNMNLEY 100 IEK +LN++LQ+AN LQ+Y+ +++ELT S+ERT +AQELHDSLGH L+AL M+LE+ Sbjct: 113 IEKEEVNQLNEKLQLANIKLQQYTLEVEELTASKERTMMAQELHDSLGHSLMALIMHLEF 172 Query: 101 ASTIVDVETDKAKLAIQKSQQLSKECIVNLRKTVVLLGDERASKELLQSLHEIFDNFLET 160 A I + + +K + KS+ ++K I +LR+ V LL +ER K S+ I +NF Sbjct: 173 ARKIYNAKPEKVNEVLAKSEDIAKSSISSLREAVNLLKEEREIKHFNDSIQGIINNFQML 232 Query: 161 NKIQFELNMDEDIEYVDSDIKNCIYKTVQESITNGIKHGQATHFSIAIHKYSDHISLLVH 220 N I+ N D+D++ + + IKN +YKT+QESITN IKHG+AT +I I + + I L+++ Sbjct: 233 NNIKIYFNTDKDLDNLSASIKNSMYKTIQESITNSIKHGKATEININITRGNLCIRLILN 292 Query: 221 NNGADCKEIIKSKGIQGIENRILALGGKVVFYSGESSGFRVEANIPKITVD 271 +NG C +IIKS G+ GIENR+ +L G V ++S ++ GF ++ +IP + D Sbjct: 293 DNGVGCNKIIKSNGLIGIENRVASLNGSVKYHSNDNLGFGIDISIPILMED 343 >A6M051.1 A6M051_CLOB8 Integral membrane sensor signal transduction histidine kinase Length = 384 Score = 173 bits (439), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 96/230 (41%), Positives = 152/230 (66%) Query: 37 RNVLIEKARTQELNQELQIANTTLQEYSNKIQELTISQERTRIAQELHDSLGHYLIALNM 96 R + +E ++LN++L++AN LQE S +I+E+ IS+ERTR++QELHDSLGH L+AL M Sbjct: 154 RKLEMESKEVKQLNEKLRLANVKLQECSLEIEEVAISKERTRVSQELHDSLGHSLVALVM 213 Query: 97 NLEYASTIVDVETDKAKLAIQKSQQLSKECIVNLRKTVVLLGDERASKELLQSLHEIFDN 156 +LE+A I K + + +S+++++ I +LRKTV LL E ++L SL ++ +N Sbjct: 214 HLEFAKNICTTNPLKLEEILAQSEKIARAGINDLRKTVDLLKSEPEVQDLNASLGQLINN 273 Query: 157 FLETNKIQFELNMDEDIEYVDSDIKNCIYKTVQESITNGIKHGQATHFSIAIHKYSDHIS 216 F + ++ DIE ++ IK IYKT+QESITN +KHG AT +I I K +++ Sbjct: 274 FYLFSNLKITYTKSTDIESLNPIIKTSIYKTIQESITNSLKHGNATKINIEIIKNINNVK 333 Query: 217 LLVHNNGADCKEIIKSKGIQGIENRILALGGKVVFYSGESSGFRVEANIP 266 +++ +NG C I+KS G+ GIENRI +LGG++ ++S + GF ++ IP Sbjct: 334 VIITDNGIGCDNILKSNGLNGIENRINSLGGEISYFSYNNLGFGIKLFIP 383 >C4IBW5.1 C4IBW5_CLOBU Integral membrane sensor signal transduction histidine kinase Length = 383 Score = 172 bits (436), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 90/226 (39%), Positives = 142/226 (62%) Query: 41 IEKARTQELNQELQIANTTLQEYSNKIQELTISQERTRIAQELHDSLGHYLIALNMNLEY 100 +EK ++LN++L +ANT L EY+ I+++TI +ER+R++Q+LHDSLGH L+AL M LE+ Sbjct: 157 VEKEELEQLNKKLTVANTKLFEYAANIEKITILKERSRVSQQLHDSLGHSLMALTMYLEF 216 Query: 101 ASTIVDVETDKAKLAIQKSQQLSKECIVNLRKTVVLLGDERASKELLQSLHEIFDNFLET 160 A I + + K + +S+ + + I LR TV L+ E ++ ++ ++ NF Sbjct: 217 AEKISNKDDINLKKVLHQSKAIVQSSIAELRNTVTLMKSEPEIQDFTDAIKKLISNFHLF 276 Query: 161 NKIQFELNMDEDIEYVDSDIKNCIYKTVQESITNGIKHGQATHFSIAIHKYSDHISLLVH 220 N I+ ++ I+ +D+ IK +Y T+QESITNG+KHG AT I I + +D++ +L+ Sbjct: 277 NYIKINYYINRSIDDLDNSIKASLYTTIQESITNGLKHGNATKIDIEILRSNDNLEILIT 336 Query: 221 NNGADCKEIIKSKGIQGIENRILALGGKVVFYSGESSGFRVEANIP 266 NNG C I+KS G+ GI+NRI ALGG + S + GF + IP Sbjct: 337 NNGVVCNNIVKSNGLVGIDNRIKALGGTTNYISNTNLGFCINIFIP 382 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.133 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,355,506,912 Number of extensions: 49740117 Number of successful extensions: 204635 Number of sequences better than 1.0e-05: 2283 Number of HSP's gapped: 203871 Number of HSP's successfully gapped: 2283 Length of query: 281 Length of database: 3,060,696,203 Length adjustment: 134 Effective length of query: 147 Effective length of database: 1,798,280,193 Effective search space: 264347188371 Effective search space used: 264347188371 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 130 (54.7 bits)