BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0490.0048.p (185 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KJ27.1 B3KJ27_9BACI Guanylate kinase EC=2.7.4.8 323 6e-87 B1DHM5.1 B1DHM5_9BACL Guanylate kinase EC=2.7.4.8 301 2e-80 Q9K9Y2.1 KGUA_BACHD Guanylate kinase EC=2.7.4.8 268 2e-70 C0ZG02.1 C0ZG02_BREBN Guanylate kinase EC=2.7.4.8 263 8e-69 Q5WFK3.1 KGUA_BACSK Guanylate kinase EC=2.7.4.8 262 9e-69 >B3KJ27.1 B3KJ27_9BACI Guanylate kinase EC=2.7.4.8 Length = 190 Score = 323 bits (827), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 154/185 (83%), Positives = 170/185 (91%) Query: 1 LLIILSGPSGVGKGTVCTALRPKMPELVYSVSATTRQPREGEENGVNYFFKTREQFAAMI 60 LLI+LSGPSGVGKGTVCTALR ++PELVYSVSATTR PR GE NGVNYFFK+REQF MI Sbjct: 5 LLIVLSGPSGVGKGTVCTALRSRVPELVYSVSATTRSPRLGEVNGVNYFFKSREQFMDMI 64 Query: 61 EADQLLEYAEYVGNYYGTPRDFVERTLDSGRDIILEIEVQGALKVKEKFPEGIFVFLLPP 120 E DQLLEYAEYVGNYYGTPRDFVE TL +G+DIILEIEVQGALKVKEKFP+GIFVFL+PP Sbjct: 65 ENDQLLEYAEYVGNYYGTPRDFVEETLATGKDIILEIEVQGALKVKEKFPDGIFVFLMPP 124 Query: 121 SMDELKDRIRGRGTEHPDVISHRMSVAEDEISLIRHYDYAVVNDEIDLACKRIESIIIAE 180 S+DELKDRI+GRGTE I HRMSVA DEI+L++HYDYAVVNDEI+LAC+RI+SIIIAE Sbjct: 125 SLDELKDRIQGRGTESQATIDHRMSVAVDEINLLQHYDYAVVNDEINLACERIQSIIIAE 184 Query: 181 HCKVR 185 HCKVR Sbjct: 185 HCKVR 189 >B1DHM5.1 B1DHM5_9BACL Guanylate kinase EC=2.7.4.8 Length = 205 Score = 301 bits (771), Expect = 2e-80, Method: Compositional matrix adjust. Identities = 142/183 (77%), Positives = 163/183 (89%) Query: 1 LLIILSGPSGVGKGTVCTALRPKMPELVYSVSATTRQPREGEENGVNYFFKTREQFAAMI 60 LLI+LSGPSGVGKGTVC+ LR K+PELVYSVSATTR+PR+GE +G+NYFFKT+EQF MI Sbjct: 5 LLIVLSGPSGVGKGTVCSVLRQKVPELVYSVSATTRKPRQGEIDGINYFFKTKEQFKEMI 64 Query: 61 EADQLLEYAEYVGNYYGTPRDFVERTLDSGRDIILEIEVQGALKVKEKFPEGIFVFLLPP 120 D LLE+AEYVGN YGTPRDFVE TL SG+D+ILEIEVQGALKVKEKFPEG+FVFLLPP Sbjct: 65 AKDALLEHAEYVGNCYGTPRDFVESTLASGKDVILEIEVQGALKVKEKFPEGVFVFLLPP 124 Query: 121 SMDELKDRIRGRGTEHPDVISHRMSVAEDEISLIRHYDYAVVNDEIDLACKRIESIIIAE 180 S+DELK RI GRGTE D I++RM+VA +E++LIRHYDYAVVNDEID AC RI+SII AE Sbjct: 125 SLDELKSRITGRGTETQDTINNRMTVAVEEMNLIRHYDYAVVNDEIDAACHRIQSIITAE 184 Query: 181 HCK 183 HC+ Sbjct: 185 HCR 187 >Q9K9Y2.1 KGUA_BACHD Guanylate kinase EC=2.7.4.8 Length = 204 Score = 268 bits (684), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 123/183 (67%), Positives = 156/183 (85%) Query: 1 LLIILSGPSGVGKGTVCTALRPKMPELVYSVSATTRQPREGEENGVNYFFKTREQFAAMI 60 LLI+LSGP+GVGKGTVC+ALR + YSVSATTR PR+GE +GVNYFFK+REQF AMI Sbjct: 7 LLIVLSGPAGVGKGTVCSALRKHDTNIQYSVSATTRAPRKGEVDGVNYFFKSREQFEAMI 66 Query: 61 EADQLLEYAEYVGNYYGTPRDFVERTLDSGRDIILEIEVQGALKVKEKFPEGIFVFLLPP 120 E ++LLE+AEYVGNYYGTP +V T+DSG+DIILEIEVQGALKV+E+FPEG+F+FL+PP Sbjct: 67 EKEELLEWAEYVGNYYGTPIQYVRETIDSGKDIILEIEVQGALKVRERFPEGVFIFLMPP 126 Query: 121 SMDELKDRIRGRGTEHPDVISHRMSVAEDEISLIRHYDYAVVNDEIDLACKRIESIIIAE 180 S+ EL+ RI GRGTE +VI+ RM+VA++EI +++ YDY V NDE++LA RI++I+ AE Sbjct: 127 SLAELRSRIVGRGTETEEVINKRMNVAKEEIEMMKKYDYVVENDEVELAVDRIKAIVTAE 186 Query: 181 HCK 183 HCK Sbjct: 187 HCK 189 >C0ZG02.1 C0ZG02_BREBN Guanylate kinase EC=2.7.4.8 Length = 206 Score = 263 bits (671), Expect = 8e-69, Method: Compositional matrix adjust. Identities = 125/183 (68%), Positives = 148/183 (80%) Query: 1 LLIILSGPSGVGKGTVCTALRPKMPELVYSVSATTRQPREGEENGVNYFFKTREQFAAMI 60 LL++LSGP+GVGKGTVC ALR MP LVYSVSATTRQPR GE GVNYFFK++E+F MI Sbjct: 8 LLLVLSGPAGVGKGTVCKALREVMPGLVYSVSATTRQPRPGEVEGVNYFFKSQEEFKRMI 67 Query: 61 EADQLLEYAEYVGNYYGTPRDFVERTLDSGRDIILEIEVQGALKVKEKFPEGIFVFLLPP 120 E D LLE+AEYVGNYYGTPR FV+ L+ GRD+ILEIEVQGAL+VKE FP+G F+FL PP Sbjct: 68 EEDALLEWAEYVGNYYGTPRQFVDDMLNEGRDVILEIEVQGALQVKESFPQGTFLFLAPP 127 Query: 121 SMDELKDRIRGRGTEHPDVISHRMSVAEDEISLIRHYDYAVVNDEIDLACKRIESIIIAE 180 ++EL++RI GRGTE ++I RM VA EI L+ HYDY VVND I+ AC RI++II AE Sbjct: 128 DLNELENRIVGRGTESQEIIRKRMEVARAEIELMDHYDYVVVNDVIESACDRIQAIITAE 187 Query: 181 HCK 183 H K Sbjct: 188 HLK 190 >Q5WFK3.1 KGUA_BACSK Guanylate kinase EC=2.7.4.8 Length = 205 Score = 262 bits (670), Expect = 9e-69, Method: Compositional matrix adjust. Identities = 121/183 (66%), Positives = 154/183 (84%) Query: 1 LLIILSGPSGVGKGTVCTALRPKMPELVYSVSATTRQPREGEENGVNYFFKTREQFAAMI 60 LLI+LSGP+GVGKGTVC ALR + + YSVSATTR+PREGE++GVNYFFKTREQF MI Sbjct: 7 LLIVLSGPAGVGKGTVCGALRNQNTAIEYSVSATTRKPREGEKHGVNYFFKTREQFEQMI 66 Query: 61 EADQLLEYAEYVGNYYGTPRDFVERTLDSGRDIILEIEVQGALKVKEKFPEGIFVFLLPP 120 E +LLE+AEYVGNYYGTP D+V+ T+++G+DIILEIEVQGA KV+ FPEG+F+FL PP Sbjct: 67 EDGKLLEWAEYVGNYYGTPIDYVQETINAGKDIILEIEVQGAQKVRTVFPEGVFIFLAPP 126 Query: 121 SMDELKDRIRGRGTEHPDVISHRMSVAEDEISLIRHYDYAVVNDEIDLACKRIESIIIAE 180 S+ EL+DRI GRGTE D+I+ RM+VA++EI L+ YDY V ND+++ A +RI++I+ AE Sbjct: 127 SLKELRDRIVGRGTETEDIINERMTVAKEEIDLMTMYDYVVENDKVEWAVERIKAIVTAE 186 Query: 181 HCK 183 HCK Sbjct: 187 HCK 189 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.139 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,117,903,946 Number of extensions: 45697929 Number of successful extensions: 176347 Number of sequences better than 1.0e-05: 2102 Number of HSP's gapped: 174683 Number of HSP's successfully gapped: 2106 Length of query: 185 Length of database: 3,060,696,203 Length adjustment: 127 Effective length of query: 58 Effective length of database: 1,864,227,298 Effective search space: 108125183284 Effective search space used: 108125183284 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 127 (53.5 bits)