BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0490.0046.p (386 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KJ29.1 B3KJ29_9BACI Phosphopantothenoylcysteine decarboxylase/... 513 e-144 B1DHL7.1 B1DHL7_9BACL Phosphopantothenoylcysteine decarboxylase/... 454 e-126 B7GGH2.1 B7GGH2_ANOFW Phosphopantothenoylcysteine synthetase/dec... 421 e-116 B4AE51.1 B4AE51_BACPU Phosphopantothenoylcysteine decarboxylase/... 409 e-112 A8FD35.1 A8FD35_BACP2 Bifunctional phosphopantothenoylcysteine d... 407 e-111 >B3KJ29.1 B3KJ29_9BACI Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase EC=4.1.1.36 EC=6.3.2.5 Length = 418 Score = 513 bits (1322), Expect = e-144, Method: Compositional matrix adjust. Identities = 266/397 (67%), Positives = 305/397 (76%), Gaps = 18/397 (4%) Query: 1 LTSKLTQKGATVHVIMTASAKQFITELTLQSLSKQRVYSDTFQERDPSSISHIDLADSAD 60 L S+L Q+GA VHVIMT SAKQFI ELTLQ+L+K VYSDTF ERDPS +SHI LAD AD Sbjct: 23 LCSRLVQRGADVHVIMTESAKQFIPELTLQTLTKNPVYSDTFDERDPSVVSHIHLADLAD 82 Query: 61 LVLVAPATANIIAKMAHGLADDMLSTXXXXXXXXXXXXXXXNVHMYQHPAVMDNINTLYK 120 LVL+APATANII KMAHGLADDML+T NVHMY HPAVM N+ TL Sbjct: 83 LVLIAPATANIIGKMAHGLADDMLTTTLLATTAPVMISPAMNVHMYTHPAVMANMETLVS 142 Query: 121 RGVKFIEPGEGQLACGYVGKGRLEEPEEIVKVVEQFFALQGSAA--------------NG 166 RGV IEPGEG LACGYVGKGR+EEP+ IV VVE+FF QG AA G Sbjct: 143 RGVSMIEPGEGLLACGYVGKGRMEEPDTIVDVVERFF--QGRAAESAASSNQDVESGSTG 200 Query: 167 PLAGKKVVITAGGTIERIDPVRYITNDSSGKMGFALSRAARAMGAEVTLIAARTDEAPPQ 226 L GKKVV+TAGGTIERIDPVRYITNDSSGKMGFA+++AA+ +GA+V LIAA TDEAPP+ Sbjct: 201 ILHGKKVVVTAGGTIERIDPVRYITNDSSGKMGFAIAKAAKQLGADVHLIAAHTDEAPPE 260 Query: 227 DPEIDVVRVESAADMYEAVLNAWQDCDILVKAAAVSDYRPRQSAESKIKKSGDTLSLELV 286 I RVESA DMYEAV + DI+VKAAAV+DYRP ++A SKIKK G+T++L+LV Sbjct: 261 G--IPAERVESAQDMYEAVQRVFDTSDIVVKAAAVADYRPAEAATSKIKKRGETMTLDLV 318 Query: 287 KTTDILENLGKQKGKQFLIGFAAETGNAEFYARDKLIRKNLDLIVANDVTMEGAGFGTDT 346 KTTDILE+LG+QK QFLIGFAAET E +AR+KL RKN DLIVANDVT EGAGFGTDT Sbjct: 319 KTTDILESLGRQKTSQFLIGFAAETDTVEQFAREKLKRKNCDLIVANDVTQEGAGFGTDT 378 Query: 347 NIVSVYDAEGLVLDLPQTSKDEVARQLLQLAAKRISG 383 N V ++DAEGLVL LP SK+EVA +LL LAA+R++G Sbjct: 379 NSVHIFDAEGLVLQLPVMSKEEVAMRLLTLAAERLTG 415 >B1DHL7.1 B1DHL7_9BACL Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase EC=4.1.1.36 EC=6.3.2.5 Length = 411 Score = 454 bits (1167), Expect = e-126, Method: Compositional matrix adjust. Identities = 229/382 (59%), Positives = 281/382 (73%), Gaps = 5/382 (1%) Query: 1 LTSKLTQKGATVHVIMTASAKQFITELTLQSLSKQRVYSDTFQERDPSSISHIDLADSAD 60 L SKL Q GA VHVIMT SA +FIT LTLQ+LS+ V+ DTF E+DPS ++HIDLAD AD Sbjct: 23 LCSKLVQAGAEVHVIMTESATKFITPLTLQTLSRHPVHIDTFDEKDPSVVTHIDLADRAD 82 Query: 61 LVLVAPATANIIAKMAHGLADDMLSTXXXXXXXXXXXXXXXNVHMYQHPAVMDNINTLYK 120 LV++APATANII K+A+GLADDMLST NVHMY+HPAV+ N+ L Sbjct: 83 LVVIAPATANIIGKVANGLADDMLSTTLLAATSPVLVAPAMNVHMYEHPAVVRNLELLAS 142 Query: 121 RGVKFIEPGEGQLACGYVGKGRLEEPEEIVKVVEQFFALQGSAANGPLAGKKVVITAGGT 180 RGV F+EPG GQLACGYV KGRL EPE+IV V + +G LAGK+V++TAGGT Sbjct: 143 RGVMFVEPGTGQLACGYVAKGRLAEPEDIVIAVHSLLK---AKEHGTLAGKRVLVTAGGT 199 Query: 181 IERIDPVRYITNDSSGKMGFALSRAARAMGAEVTLIAARTDEAPPQDPEIDVVRVESAAD 240 +ER+DPVRY+TNDSSGKMGFA++ AA+ MGAEVT+IA RT PP + V+RVESA Sbjct: 200 MERLDPVRYLTNDSSGKMGFAIAEAAKVMGAEVTVIAGRTSVDPPAG--VKVIRVESARQ 257 Query: 241 MYEAVLNAWQDCDILVKAAAVSDYRPRQSAESKIKKSGDTLSLELVKTTDILENLGKQKG 300 M +AVL +++ DI+VK+AAV+DYRP KIKKSG+TL+LEL KTTDIL+ LG++K Sbjct: 258 MLDAVLERFEESDIVVKSAAVADYRPVTRHGQKIKKSGETLTLELEKTTDILQTLGERKT 317 Query: 301 KQFLIGFAAETGNAEFYARDKLIRKNLDLIVANDVTMEGAGFGTDTNIVSVYDAEGLVLD 360 Q LIGFAAET E YA DKL RKN DLIV NDV+ EGAGF DTNIV +Y GL+ Sbjct: 318 HQLLIGFAAETEQLEKYAMDKLKRKNADLIVGNDVSQEGAGFNGDTNIVQLYGPSGLIEA 377 Query: 361 LPQTSKDEVARQLLQLAAKRIS 382 +P SK E A+++L +AA+R+S Sbjct: 378 MPLLSKRETAQRILTIAARRLS 399 >B7GGH2.1 B7GGH2_ANOFW Phosphopantothenoylcysteine synthetase/decarboxylase Length = 400 Score = 421 bits (1083), Expect = e-116, Method: Compositional matrix adjust. Identities = 212/383 (55%), Positives = 270/383 (70%), Gaps = 7/383 (1%) Query: 1 LTSKLTQKGATVHVIMTASAKQFITELTLQSLSKQRVYSDTFQERDPSSISHIDLADSAD 60 LTSKL Q GA V V+MT +A QF+T LT Q+LSK VY DTF E+ P I+HIDLAD A Sbjct: 23 LTSKLVQVGANVKVVMTEAACQFVTPLTFQALSKNEVYVDTFDEKKPHVIAHIDLADWAH 82 Query: 61 LVLVAPATANIIAKMAHGLADDMLSTXXXXXXXXXXXXXXXNVHMYQHPAVMDNINTLYK 120 +VLVAPATAN IAK+AHGLAD+M++T NVHMY+HP+V N+ TL Sbjct: 83 VVLVAPATANTIAKLAHGLADNMVTTILLATKAPVWIAPAMNVHMYEHPSVQQNMRTLQS 142 Query: 121 RGVKFIEPGEGQLACGYVGKGRLEEPEEIVKVVEQFFALQGSAANGPLAGKKVVITAGGT 180 G +FIEP EG LACGYVGKGRLEEPE IV ++EQ F A N L GKKV++TAG T Sbjct: 143 FGYRFIEPAEGMLACGYVGKGRLEEPETIVTLLEQHF-----ATNHILKGKKVLVTAGPT 197 Query: 181 IERIDPVRYITNDSSGKMGFALSRAARAMGAEVTLIAARTDEAPPQDPEIDVVRVESAAD 240 E++DPVR+ +N S+GKMG+AL+ AAR GA+V LI+ T A P + ++RVESA Sbjct: 198 REKLDPVRFFSNHSTGKMGYALAEAARDFGADVVLISGPT--ALPSPSGVQMIRVESAQH 255 Query: 241 MYEAVLNAWQDCDILVKAAAVSDYRPRQSAESKIKKSGDTLSLELVKTTDILENLGKQKG 300 MYE V+N + D DI++K AAV+DYRP+ A++KIKK ++ L +T DIL+ LG+QK Sbjct: 256 MYEEVMNHFHDSDIVIKTAAVADYRPKYVADNKIKKQQGDYTVVLERTIDILQTLGEQKT 315 Query: 301 KQFLIGFAAETGNAEFYARDKLIRKNLDLIVANDVTMEGAGFGTDTNIVSVYDAEGLVLD 360 QFL+GFAAET + E YA+DKL RKN D+IVAN+V EGAGFGTDTNIV+++ +G V Sbjct: 316 HQFLVGFAAETNDVERYAKDKLARKNADMIVANNVVQEGAGFGTDTNIVTLFKRDGTVKS 375 Query: 361 LPQTSKDEVARQLLQLAAKRISG 383 LP K EVA+++L+ + I G Sbjct: 376 LPLLPKSEVAKEILREVHREIEG 398 >B4AE51.1 B4AE51_BACPU Phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase EC=4.1.1.36 EC=6.3.2.5 Length = 405 Score = 409 bits (1051), Expect = e-112, Method: Compositional matrix adjust. Identities = 204/377 (54%), Positives = 266/377 (70%), Gaps = 5/377 (1%) Query: 1 LTSKLTQKGATVHVIMTASAKQFITELTLQSLSKQRVYSDTFQERDPSSISHIDLADSAD 60 LTSKL Q GA V VIMT SA++F++ LT Q+LS+ VY DTF+E +P I+HID+AD AD Sbjct: 23 LTSKLVQAGANVRVIMTESAREFVSPLTFQALSRHEVYVDTFKENNPKVIAHIDVADWAD 82 Query: 61 LVLVAPATANIIAKMAHGLADDMLSTXXXXXXXXXXXXXXXNVHMYQHPAVMDNINTLYK 120 L+LVAPATA+ I KMA GLADDML+T NVHMY HPAV NI TLY+ Sbjct: 83 LILVAPATAHTIGKMAAGLADDMLTTTLLASTAPVWIAPAMNVHMYDHPAVKRNIRTLYE 142 Query: 121 RGVKFIEPGEGQLACGYVGKGRLEEPEEIVKVVEQFFALQGSAANGPLAGKKVVITAGGT 180 G +FIEP EG LACGY+GKGRLEEPE+IV+ + FF N PL+GKKVV+TAG T Sbjct: 143 DGYQFIEPSEGYLACGYIGKGRLEEPEKIVEHIRAFFE---EPKNLPLSGKKVVVTAGPT 199 Query: 181 IERIDPVRYITNDSSGKMGFALSRAARAMGAEVTLIAARTDEAPPQDPEIDVVRVESAAD 240 E IDPVR+ TN SSGKMG+A++ AA+ MGA+VTLI+ P + VV VESA D Sbjct: 200 REVIDPVRFFTNRSSGKMGYAIAEAAQQMGADVTLISGPVSLTAPN--HVHVVHVESAED 257 Query: 241 MYEAVLNAWQDCDILVKAAAVSDYRPRQSAESKIKKSGDTLSLELVKTTDILENLGKQKG 300 MY+A L +++ D+++K+AAV+DY P S K+KK L +E +T DIL+ LGK+K Sbjct: 258 MYQAALAVYEEADLVIKSAAVADYTPVTSYPHKMKKQDGALEIEFTRTKDILKELGKRKE 317 Query: 301 KQFLIGFAAETGNAEFYARDKLIRKNLDLIVANDVTMEGAGFGTDTNIVSVYDAEGLVLD 360 Q L+GFAAET + ++YA+ K+ K+LD+IVAN+VT EGAGFGTDTN+ ++ A+G + Sbjct: 318 HQVLVGFAAETQDVKYYAKKKIESKHLDMIVANNVTKEGAGFGTDTNVAAIIKADGTTTE 377 Query: 361 LPQTSKDEVARQLLQLA 377 LP SK ++A ++L+ A Sbjct: 378 LPMMSKKDLAFEILKEA 394 >A8FD35.1 A8FD35_BACP2 Bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase EC=4.1.1.36 EC=6.3.2.5 Length = 405 Score = 407 bits (1045), Expect = e-111, Method: Compositional matrix adjust. Identities = 204/377 (54%), Positives = 264/377 (70%), Gaps = 5/377 (1%) Query: 1 LTSKLTQKGATVHVIMTASAKQFITELTLQSLSKQRVYSDTFQERDPSSISHIDLADSAD 60 LTSKL Q GA V VIMT SA++F++ LT Q+LS+ VY DTF+E +P I+HID+AD AD Sbjct: 23 LTSKLVQAGANVRVIMTESAREFVSPLTFQALSRHEVYVDTFKENNPKVIAHIDVADWAD 82 Query: 61 LVLVAPATANIIAKMAHGLADDMLSTXXXXXXXXXXXXXXXNVHMYQHPAVMDNINTLYK 120 L+LVAPATA+ I KMA GLADDML+T NVHMY HPAV NI TLY+ Sbjct: 83 LILVAPATAHTIGKMAAGLADDMLTTTLLASTAPVWIAPAMNVHMYDHPAVKRNIRTLYE 142 Query: 121 RGVKFIEPGEGQLACGYVGKGRLEEPEEIVKVVEQFFALQGSAANGPLAGKKVVITAGGT 180 G +FIEP EG LACGY+GKGRLEEPE+IV+ + FF S PL+GKKVV+TAG T Sbjct: 143 DGYRFIEPSEGYLACGYIGKGRLEEPEKIVEHIRAFFEEPKSL---PLSGKKVVVTAGPT 199 Query: 181 IERIDPVRYITNDSSGKMGFALSRAARAMGAEVTLIAARTDEAPPQDPEIDVVRVESAAD 240 E IDPVR+ TN SSGKMG+A++ AA+ MGA+VTLI+ P + VV VESA D Sbjct: 200 REVIDPVRFFTNRSSGKMGYAIAEAAQQMGADVTLISGPVSLTEPN--HVHVVHVESAED 257 Query: 241 MYEAVLNAWQDCDILVKAAAVSDYRPRQSAESKIKKSGDTLSLELVKTTDILENLGKQKG 300 MY+A L +++ D+ +K+AAV+DY P S K+KK L +E +T DIL+ LGK+K Sbjct: 258 MYQAALAEYEEADLFIKSAAVADYTPVTSYPHKMKKQDGALEIEFTRTKDILKELGKRKE 317 Query: 301 KQFLIGFAAETGNAEFYARDKLIRKNLDLIVANDVTMEGAGFGTDTNIVSVYDAEGLVLD 360 Q L+GFAAET + E+YA+ K+ K+LD+IVAN+VT EGAGF TDTN+ ++ A+G + Sbjct: 318 HQVLVGFAAETQDVEYYAKKKIESKHLDMIVANNVTKEGAGFATDTNVAAIIKADGTTKE 377 Query: 361 LPQTSKDEVARQLLQLA 377 LP SK ++A ++L+ A Sbjct: 378 LPMMSKKDLAFEILKEA 394 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.131 0.358 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,988,221,508 Number of extensions: 76197139 Number of successful extensions: 235012 Number of sequences better than 1.0e-05: 1688 Number of HSP's gapped: 230171 Number of HSP's successfully gapped: 1695 Length of query: 386 Length of database: 3,060,696,203 Length adjustment: 137 Effective length of query: 249 Effective length of database: 1,770,017,148 Effective search space: 440734269852 Effective search space used: 440734269852 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 132 (55.5 bits)