BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0490.0026.p (415 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DA64.1 B1DA64_9BACL Sodium/hydrogen exchanger 436 e-120 C0Z7J6.1 C0Z7J6_BREBN Potassium-efflux system protein YhaU 425 e-117 B3KFR9.1 B3KFR9_9BACI Sodium/hydrogen exchanger 410 e-112 Q81XF1.1 Q81XF1_BACAN Sodium/hydrogen exchanger family protein 374 e-102 C3P033.1 C3P033_BACAA Sodium/hydrogen exchanger family protein 374 e-102 >B1DA64.1 B1DA64_9BACL Sodium/hydrogen exchanger Length = 405 Score = 436 bits (1122), Expect = e-120, Method: Compositional matrix adjust. Identities = 232/407 (57%), Positives = 271/407 (66%), Gaps = 2/407 (0%) Query: 1 MNHYIVFEXXXXXXXXXXXXXXSTKLRFSVIPFYILIGMAVGPHAFKIWHLDFRFIESAA 60 M+H I+ E S K+RFSVIPFYILIGMAVGPH+ + WH DFRFIESA Sbjct: 1 MDH-IILEVGLAIALIALAGLLSAKIRFSVIPFYILIGMAVGPHSVEFWHFDFRFIESAP 59 Query: 61 LIEFMGRIGVLFLLFYLGLEFSVGRLVKAGRSIVTGGTIYILINFTLGLVLGWGLGFPLE 120 LIEFMGR+GVLFLLFYLGLEFSVGRL+K+GRSI GGTIYI INFTLGL+ GW GFP + Sbjct: 60 LIEFMGRLGVLFLLFYLGLEFSVGRLIKSGRSIAVGGTIYIAINFTLGLLFGWLSGFPFQ 119 Query: 121 EILXXXXXXXXXXXXXXXKVLVDLKRTANPETEMILGIIMFEDVFLAVYIXXXXXXXXXX 180 E L KVLVDLKRTANPETEMILGIIMFEDVFLAVYI Sbjct: 120 ETLVIAGITTISSSAIVAKVLVDLKRTANPETEMILGIIMFEDVFLAVYISILSGLILSG 179 Query: 181 XXXXXXXXXXXXXXXXYMLALLVIGRKLVPWLNRVLNIRSGEXXXXXXXXXXXXXXXXSE 240 +MLALL +GRK P LN++LNIRS E SE Sbjct: 180 STSIGGIILSTVIALVFMLALLTLGRKAAPMLNKLLNIRSNELFALVIFAGLFLVAGLSE 239 Query: 241 TIHXXXXXXXXXXXXXXXXTEHVKRIEKLVIPXXXXXXXXXXXXXGLTIDPLSLGGDALW 300 TIH TEH+KRIEKL++P GLTIDP +LGG A+W Sbjct: 240 TIHVAEAIGALLFGLVLAETEHMKRIEKLILPFRDFFGAVFFFSFGLTIDPTALGG-AVW 298 Query: 301 YSLAAVIITLIGNFAAGMLAGRSAGLSPRSSANIGLTIVSRGEFSIIMANLGKAGGLLAI 360 SLAAV +TLIGN AGMLAGRSAGLSP++S NIGLTIVSRGEFSIIMAN+ KAG L+A+ Sbjct: 299 LSLAAVAVTLIGNLTAGMLAGRSAGLSPKASVNIGLTIVSRGEFSIIMANMAKAGALMAV 358 Query: 361 LQPFAAMYVLILAILGPLLTKESKTIYKLLDKVFKFEKRHLARSSRQ 407 +QPFAA+YVLILAILGPLLTKE+K I+ LL+++F+++++ + S + Sbjct: 359 IQPFAALYVLILAILGPLLTKENKLIFNLLNRLFRWDRKQTSTSQSK 405 >C0Z7J6.1 C0Z7J6_BREBN Potassium-efflux system protein YhaU Length = 410 Score = 425 bits (1092), Expect = e-117, Method: Compositional matrix adjust. Identities = 230/409 (56%), Positives = 265/409 (64%), Gaps = 1/409 (0%) Query: 3 HYIVFEXXXXXXXXXXXXXXSTKLRFSVIPFYILIGMAVGPHAFKIWHLDFRFIESAALI 62 +IVFE S KL+FS++PFYIL+GM VGPHA I D RFI SA LI Sbjct: 2 EHIVFEVGLALALIAIAGFLSMKLKFSIVPFYILVGMIVGPHAPDIGLFDLRFISSAPLI 61 Query: 63 EFMGRIGVLFLLFYLGLEFSVGRLVKAGRSIVTGGTIYILINFTLGLVLGWGLGFPLEEI 122 EFMGR+GVLFLLFYLGLEFSVGRL+KAGRSI GGTIYI+INFTLGL+ GW GFPL+E+ Sbjct: 62 EFMGRLGVLFLLFYLGLEFSVGRLIKAGRSIAVGGTIYIVINFTLGLLFGWAAGFPLKEV 121 Query: 123 LXXXXXXXXXXXXXXXKVLVDLKRTANPETEMILGIIMFEDVFLAVYIXXXXXXXXXXXX 182 L KVLVDLKRTAN ETEMILGIIMFED+FLAVYI Sbjct: 122 LIIAGITTISSSAIVAKVLVDLKRTANRETEMILGIIMFEDIFLAVYISIVSGLVLSGAT 181 Query: 183 XXXXXXXXXXXXXXYMLALLVIGRKLVPWLNRVLNIRSGEXXXXXXXXXXXXXXXXSETI 242 YML L+++GRKLVP+LNR LNI+S E SETI Sbjct: 182 SLAGVLSSALIALGYMLLLIIVGRKLVPFLNRALNIKSNEVFMITVFAALFLIAGFSETI 241 Query: 243 HXXXXXXXXXXXXXXXXTEHVKRIEKLVIPXXXXXXXXXXXXXGLTIDPLSLGGDALWYS 302 H T+H+KRIE L++P GLTIDPLSLGG A+W S Sbjct: 242 HVAEAIGALLVGLVLAETQHMKRIEHLILPFRDFFGAMFFFSFGLTIDPLSLGG-AVWLS 300 Query: 303 LAAVIITLIGNFAAGMLAGRSAGLSPRSSANIGLTIVSRGEFSIIMANLGKAGGLLAILQ 362 + AV +TL GN AG+LAGRSAGL P++S NIGLTIVSRGEFSIIMANLGKAG L+ ILQ Sbjct: 301 IGAVALTLFGNVVAGLLAGRSAGLPPKASTNIGLTIVSRGEFSIIMANLGKAGALMEILQ 360 Query: 363 PFAAMYVLILAILGPLLTKESKTIYKLLDKVFKFEKRHLARSSRQAATA 411 PFAA+YVLILAILGPLLTKESK IYKLL+ VF+ +++ + A A Sbjct: 361 PFAALYVLILAILGPLLTKESKHIYKLLNAVFRLDRKTPVKEPANKADA 409 >B3KFR9.1 B3KFR9_9BACI Sodium/hydrogen exchanger Length = 414 Score = 410 bits (1053), Expect = e-112, Method: Compositional matrix adjust. Identities = 226/399 (56%), Positives = 260/399 (65%), Gaps = 2/399 (0%) Query: 1 MNHYIVFEXXXXXXXXXXXXXXSTKLRFSVIPFYILIGMAVGPHAFKIWHLDFRFIESAA 60 M+H +V E S KLRFSV+PFYIL+GMAVGPHAF DFRFIESA Sbjct: 1 MDH-LVLEVGLAIALIALAGLLSAKLRFSVVPFYILVGMAVGPHAFHFGSFDFRFIESAP 59 Query: 61 LIEFMGRIGVLFLLFYLGLEFSVGRLVKAGRSIVTGGTIYILINFTLGLVLGWGLGFPLE 120 LI+FMGRIGVLFLLFYLGLEFSVGRL+K+GRSIV GG+IYI INFTLGL++G GFPL Sbjct: 60 LIDFMGRIGVLFLLFYLGLEFSVGRLIKSGRSIVVGGSIYIAINFTLGLMIGIFAGFPLA 119 Query: 121 EILXXXXXXXXXXXXXXXKVLVDLKRTANPETEMILGIIMFEDVFLAVYIXXXXXXXXXX 180 E L KVLVDL+RTANPETEMILGIIMFEDVFLAVYI Sbjct: 120 ETLIVAGITTISSSAIVAKVLVDLRRTANPETEMILGIIMFEDVFLAVYISILSGLVLSG 179 Query: 181 XXXXXXXXXXXXXXXXYMLALLVIGRKLVPWLNRVLNIRSGEXXXXXXXXXXXXXXXXSE 240 +ML ++++GRK VP LN+ LNIRS E +E Sbjct: 180 SSSLGGVLISAVIALGFMLLVIIVGRKAVPLLNKALNIRSNELFALVVFGALFLLAGFAE 239 Query: 241 TIHXXXXXXXXXXXXXXXXTEHVKRIEKLVIPXXXXXXXXXXXXXGLTIDPLSLGGDALW 300 TIH TEH +RIE L++P GLTI P LGG A+W Sbjct: 240 TIHVAEAIGALLVGLVLAETEHRERIEHLILPFRDFFGAIFFFSFGLTIVPSELGG-AVW 298 Query: 301 YSLAAVIITLIGNFAAGMLAGRSAGLSPRSSANIGLTIVSRGEFSIIMANLGKAGGLLAI 360 SL AVIITL+GNF AGMLAGRSAGLS ++S+NIGLTIVSRGEFSII+AN+GKAGGL Sbjct: 299 LSLIAVIITLLGNFIAGMLAGRSAGLSSKASSNIGLTIVSRGEFSIILANMGKAGGLATF 358 Query: 361 LQPFAAMYVLILAILGPLLTKESKTIYKLLDKVFKFEKR 399 +QPFAA+YVLILAILGPLLTKESK +Y L+K+FKF+ Sbjct: 359 IQPFAALYVLILAILGPLLTKESKHVYNFLNKIFKFKDH 397 >Q81XF1.1 Q81XF1_BACAN Sodium/hydrogen exchanger family protein Length = 399 Score = 374 bits (960), Expect = e-102, Method: Compositional matrix adjust. Identities = 204/395 (51%), Positives = 255/395 (64%), Gaps = 1/395 (0%) Query: 5 IVFEXXXXXXXXXXXXXXSTKLRFSVIPFYILIGMAVGPHAFKIWHLDFRFIESAALIEF 64 ++FE + K +FSVIPF I++GM VGPHA I +DF+FIESA++I F Sbjct: 4 LIFEVGTALVLVAIAAVIAGKFKFSVIPFLIVLGMLVGPHAPTIGVIDFKFIESASVISF 63 Query: 65 MGRIGVLFLLFYLGLEFSVGRLVKAGRSIVTGGTIYILINFTLGLVLGWGLGFPLEEILX 124 +GRIGVLFLLFYLGLEFS+ +L+K+GRSI GGTIYILINF+LGL+ G+ +GFPL EIL Sbjct: 64 LGRIGVLFLLFYLGLEFSMKKLIKSGRSIAIGGTIYILINFSLGLLYGFIMGFPLLEILI 123 Query: 125 XXXXXXXXXXXXXXKVLVDLKRTANPETEMILGIIMFEDVFLAVYIXXXXXXXXXXXXXX 184 KVLVDL+RT N ETE+ILGIIMFED+FLAVY+ Sbjct: 124 IAGIITISSSAIVAKVLVDLRRTGNNETELILGIIMFEDIFLAVYLSVVSGLVLGDHASF 183 Query: 185 XXXXXXXXXXXXYMLALLVIGRKLVPWLNRVLNIRSGEXXXXXXXXXXXXXXXXSETIHX 244 YML ++ RK P LN++LNI S E SETIH Sbjct: 184 LGALTSIGIALGYMLLFFIVARKATPLLNKLLNISSDEIFIIVVFASLFFIAGFSETIHV 243 Query: 245 XXXXXXXXXXXXXXXTEHVKRIEKLVIPXXXXXXXXXXXXXGLTIDPLSLGGDALWYSLA 304 TEH RIE LV+P GL+IDP SLGG A+W +L Sbjct: 244 AEAIGALLLGLVFSETEHSDRIEHLVVPFRDFFGAIFFFSFGLSIDPFSLGG-AIWLTLG 302 Query: 305 AVIITLIGNFAAGMLAGRSAGLSPRSSANIGLTIVSRGEFSIIMANLGKAGGLLAILQPF 364 AV++T+IGNF AGM+AGR AGLS ++S NIGLTIVSRGEFSIIMAN+G AGGL+++L+PF Sbjct: 303 AVLLTIIGNFVAGMIAGRQAGLSHKASTNIGLTIVSRGEFSIIMANIGIAGGLMSVLKPF 362 Query: 365 AAMYVLILAILGPLLTKESKTIYKLLDKVFKFEKR 399 +A+YVLIL+ILGPLLTKESK +YKLL+K+FK++ + Sbjct: 363 SALYVLILSILGPLLTKESKNVYKLLNKIFKWDMK 397 >C3P033.1 C3P033_BACAA Sodium/hydrogen exchanger family protein Length = 399 Score = 374 bits (960), Expect = e-102, Method: Compositional matrix adjust. Identities = 204/395 (51%), Positives = 255/395 (64%), Gaps = 1/395 (0%) Query: 5 IVFEXXXXXXXXXXXXXXSTKLRFSVIPFYILIGMAVGPHAFKIWHLDFRFIESAALIEF 64 ++FE + K +FSVIPF I++GM VGPHA I +DF+FIESA++I F Sbjct: 4 LIFEVGTALVLVAIAAVIAGKFKFSVIPFLIVLGMLVGPHAPTIGVIDFKFIESASVISF 63 Query: 65 MGRIGVLFLLFYLGLEFSVGRLVKAGRSIVTGGTIYILINFTLGLVLGWGLGFPLEEILX 124 +GRIGVLFLLFYLGLEFS+ +L+K+GRSI GGTIYILINF+LGL+ G+ +GFPL EIL Sbjct: 64 LGRIGVLFLLFYLGLEFSMKKLIKSGRSIAIGGTIYILINFSLGLLYGFIMGFPLLEILI 123 Query: 125 XXXXXXXXXXXXXXKVLVDLKRTANPETEMILGIIMFEDVFLAVYIXXXXXXXXXXXXXX 184 KVLVDL+RT N ETE+ILGIIMFED+FLAVY+ Sbjct: 124 IAGIITISSSAIVAKVLVDLRRTGNNETELILGIIMFEDIFLAVYLSVVSGLVLGDHASF 183 Query: 185 XXXXXXXXXXXXYMLALLVIGRKLVPWLNRVLNIRSGEXXXXXXXXXXXXXXXXSETIHX 244 YML ++ RK P LN++LNI S E SETIH Sbjct: 184 LGALTSIGIALGYMLLFFIVARKATPLLNKLLNISSDEIFIIVVFASLFFIAGFSETIHV 243 Query: 245 XXXXXXXXXXXXXXXTEHVKRIEKLVIPXXXXXXXXXXXXXGLTIDPLSLGGDALWYSLA 304 TEH RIE LV+P GL+IDP SLGG A+W +L Sbjct: 244 AEAIGALLLGLVFSETEHSDRIEHLVVPFRDFFGAIFFFSFGLSIDPFSLGG-AIWLTLG 302 Query: 305 AVIITLIGNFAAGMLAGRSAGLSPRSSANIGLTIVSRGEFSIIMANLGKAGGLLAILQPF 364 AV++T+IGNF AGM+AGR AGLS ++S NIGLTIVSRGEFSIIMAN+G AGGL+++L+PF Sbjct: 303 AVLLTIIGNFVAGMIAGRQAGLSHKASTNIGLTIVSRGEFSIIMANIGIAGGLMSVLKPF 362 Query: 365 AAMYVLILAILGPLLTKESKTIYKLLDKVFKFEKR 399 +A+YVLIL+ILGPLLTKESK +YKLL+K+FK++ + Sbjct: 363 SALYVLILSILGPLLTKESKNVYKLLNKIFKWDMK 397 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.327 0.145 0.421 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,696,558,395 Number of extensions: 56306489 Number of successful extensions: 194135 Number of sequences better than 1.0e-05: 590 Number of HSP's gapped: 193598 Number of HSP's successfully gapped: 645 Length of query: 415 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 277 Effective length of database: 1,760,596,133 Effective search space: 487685128841 Effective search space used: 487685128841 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.7 bits) S2: 132 (55.5 bits)