BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0490.0016.p (601 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KGU9.1 B3KGU9_9BACI Histidine kinase internal region 452 e-125 Q65KZ4.1 Q65KZ4_BACLD YesM 406 e-111 O31516.1 YESM_BACSU Sensor histidine kinase yesM EC=2.7.13.3 395 e-108 B1DJR5.1 B1DJR5_9BACL Integral membrane sensor signal transducti... 392 e-107 B0NES5.1 B0NES5_EUBSP Putative uncharacterized protein 233 6e-59 >B3KGU9.1 B3KGU9_9BACI Histidine kinase internal region Length = 577 Score = 452 bits (1163), Expect = e-125, Method: Compositional matrix adjust. Identities = 244/580 (42%), Positives = 347/580 (59%), Gaps = 13/580 (2%) Query: 11 SAFKNPGIFNKMIMXXXXXXXXXXXXXXXXXQYVYRIYDRQIYEKASEVLGMSSVSIENE 70 + +KN I NK+ + QY + IYD Q+Y K+S+VL +SS +IE+E Sbjct: 6 TIYKNMKIKNKLSLLISLIVAMAFAFAVIVQQYAFSIYDEQLYLKSSQVLHLSSSAIESE 65 Query: 71 LKELEQLSFTVVADEQIQNCLRQLLDNPSPYERQVLHNRIINRLVAFAGAEKYVYSMILM 130 L+ +EQLSF ++ D QIQN LR + + S Y+R +L +++RL+ + G+E +YS+ L+ Sbjct: 66 LERVEQLSFNIITDTQIQNILRSIAGSESDYDRLILRQHLVDRLLNYVGSEPMLYSIHLI 125 Query: 131 DANDGVMTAGNREWLSETLQDQLRPLAIAGAGSNIW-YTQGSKNSLLAVRQIKSYTGSTF 189 D+ D G+ + ++++ LA G W Y S +LL R+I+SY+G+ F Sbjct: 126 DSYDHQQDVGSVVPIEPAKKERILQLAGDADGEERWIYPDESDPALLLSREIRSYSGTLF 185 Query: 190 TLDNLGTLXXXXXXXXXXDDSTSIAGDGGQLIVVDKGTGRSVYXXXXXXXXXXXXXXVQR 249 L+ LGT+ S AG G LIV +Y + Sbjct: 186 DLNYLGTIIIRINMDKIVRKS---AGGEGDLIVTSGAD--VIYPATPHFDPAVIQSSLSS 240 Query: 250 PEAYRTVGYSKGTYFVAKTNSSYMDWTYINATPFNEMFRQITFVKRLVVIIFGCIXXXXX 309 Y T TYF+A S WTY+N TPFN+ F+QI F+K LV+I+F I Sbjct: 241 GNGYLTREIDGHTYFIAHNRSGNTGWTYMNVTPFNQTFKQIIFIKELVIIVFTVIFAVAI 300 Query: 310 XXXYRLARSIVRPVSKLTEKMRRIEKGDL---DNLEEQALGFVSQTAQDEVSQLNRTFQM 366 R +R + RP+ L +M+ EKG+ + L + A + A +E+ L+RTF++ Sbjct: 301 LLGIRFSRGLTRPIESLITRMKLAEKGNFAEANVLPQDA----APVAMNELGLLHRTFRL 356 Query: 367 MIRRIRELIDENYAKQLVIRETELKALQAQINPHFLYNTLESINWLAKVNKQKQISDMVE 426 MI RI LI ENY+ +L+I+ETE KALQAQINPHFLYNTLES+NWLAK+NKQ QISDMV+ Sbjct: 357 MIERINALITENYSNRLLIKETEFKALQAQINPHFLYNTLESVNWLAKMNKQSQISDMVQ 416 Query: 427 ALGFLLRSSIGLKDPLISLEKELSIVRSYVIIQRTRFEERLDFRLDVPDGLLDALVPKLT 486 AL FLLR+S+ LK+P+++L +EL IVR+YVIIQ+ RFE+RL F LDV + L +PKL+ Sbjct: 417 ALAFLLRNSVSLKEPILTLGEELEIVRNYVIIQKFRFEDRLHFTLDVQEQDLHRKIPKLS 476 Query: 487 LQPLVENAIRYALEPNIEPCVISISISRTEDGLDLRVSDNGPGMTADFIRGLEQGRIQTR 546 LQPL+ENAI YALEP+++PC I++S + T + V D+GPGM D + L G + T Sbjct: 477 LQPLLENAIHYALEPSVDPCRITLSCTETPSAFCVIVEDDGPGMAPDTLTRLRSGDLATS 536 Query: 547 GEGIGLANIAERIQIVFGQEWGTEIESRPGEGTTIHVHIP 586 G GIGL NI ERI++ FG +G I+S PG GT + + +P Sbjct: 537 GNGIGLLNIEERIKLAFGDHYGLSIDSGPGLGTRVILSLP 576 >Q65KZ4.1 Q65KZ4_BACLD YesM Length = 578 Score = 406 bits (1043), Expect = e-111, Method: Compositional matrix adjust. Identities = 231/555 (41%), Positives = 326/555 (58%), Gaps = 16/555 (2%) Query: 42 QYVYRIYDRQIYEKASEVLGMSSVSIENELKELEQLSFTVVADEQIQNCLRQLLDNPSPY 101 QY +R+YD+QIY K+S+VL +SS SIE+ELK++E +S+ + D IQ L + + Y Sbjct: 33 QYAFRVYDQQIYRKSSQVLMLSSKSIEDELKKIEDVSYQITTDADIQANLLKAGRGQNKY 92 Query: 102 ERQVLHNRIINRLVAFAGAEKYVYSMILMDANDGVMTAGNREWLSETLQDQLRPL---AI 158 R + ++I ++L + G+++Y+ S+ L DA+ +AG L+E L++Q L A Sbjct: 93 GRYRIKSKIWDKLAEYTGSKRYIKSIHLFDASGTEYSAGAN--LTEALREQKNALIEKAS 150 Query: 159 AGAGSNIWYTQ-GSKNSLLAVRQIKSYTGSTFTLDNLGTLXXXXXXXXXXDDSTSIAGDG 217 GSN+W G LL+VR+I+SY LD+LGT+ D G+G Sbjct: 151 RQKGSNMWEPMPGETGELLSVREIRSY--ERLNLDHLGTVVIVADLKRVIGDLPKDWGEG 208 Query: 218 -GQLIVVDKGTGRSVYXXXXXXXXXXXXXXVQRPE-AYRTVGYSKGTYFVAKTNSSYMDW 275 G++ + D GR ++ E Y V + +FV+ S+Y +W Sbjct: 209 AGKIAMSD---GRELFFSEMPFSQTDGLRLSSHAENGYDIVEENGQRFFVSYVKSAYKNW 265 Query: 276 TYINATPFNEMFRQITFVKRLVVIIFGCIXXXXXXXXYRLARSIVRPVSKLTEKMRRIEK 335 TY + PF+ MF +I+ +K +++ +F ++AR I P+ KL M+ ++ Sbjct: 266 TYWSLIPFDAMFSKISAMKTILISLFILFFLIAVLFGRKMARGITSPIEKLVAAMKNVQN 325 Query: 336 GDLDNLEEQALGFVSQTAQDEVSQLNRTFQMMIRRIRELIDENYAKQLVIRETELKALQA 395 GD + L QDEVS LNR F M+ RI ELI ENY KQL+++ETE KALQA Sbjct: 326 GDF---KLAPLTRAPLDRQDEVSVLNRNFFTMVERINELIAENYKKQLMLKETEFKALQA 382 Query: 396 QINPHFLYNTLESINWLAKVNKQKQISDMVEALGFLLRSSIGLKDPLISLEKELSIVRSY 455 QINPHFLYNTLESINWLAK N+Q QIS M E+LGFLLR++I +K ++++E+E IVR Y Sbjct: 383 QINPHFLYNTLESINWLAKTNRQPQISKMTESLGFLLRNAINMKTDVLTIEEEAEIVRHY 442 Query: 456 VIIQRTRFEERLDFRLDVPDGLLDALVPKLTLQPLVENAIRYALEPNIEPCVISISISRT 515 IQR RFEERL F LD+ + VPKL LQPL ENAI Y LEP IEPC I I + Sbjct: 443 FTIQRFRFEERLVFELDIEPAVKKCRVPKLVLQPLAENAITYCLEPFIEPCHIQIKAYKK 502 Query: 516 EDGLDLRVSDNGPGMTADFIRGLEQGRIQTRGEGIGLANIAERIQIVFGQEWGTEIESRP 575 E+ + L V+DNGPGM DF+ + ++T G GIGL NI ERIQ++FG+ +G I S Sbjct: 503 EELVYLTVADNGPGMDEDFLEKARKELVRTTGRGIGLQNIDERIQLMFGKGYGLTISSEK 562 Query: 576 GEGTTIHVHIPYVRG 590 +GT + + IP+ G Sbjct: 563 NKGTVMMIKIPFQSG 577 >O31516.1 YESM_BACSU Sensor histidine kinase yesM EC=2.7.13.3 Length = 577 Score = 395 bits (1015), Expect = e-108, Method: Compositional matrix adjust. Identities = 225/550 (40%), Positives = 323/550 (58%), Gaps = 21/550 (3%) Query: 42 QYVYRIYDRQIYEKASEVLGMSSVSIENELKELEQLSFTVVADEQIQNCLRQLLDNPSPY 101 QY + +YD QIY K+SEVL MSS IE+ELK++E +S+ ++ DEQIQ L + + Y Sbjct: 38 QYAFHVYDEQIYRKSSEVLRMSSERIEDELKKIEDVSYEIITDEQIQRIL-SMQNRDDTY 96 Query: 102 ERQVLHNRIINRLVAFAGAEKYVYSMILMDANDGVMTAGNREW-LSETLQDQLRPLAIAG 160 ++ + + ++L +A EKY+ S+ ++DA +AG+ L + Q+++ A A Sbjct: 97 DQYQMKQELWDQLAGYASDEKYIDSIHVIDARGSEYSAGSSSSDLLQQEQEEVFKRAKAK 156 Query: 161 AGSNIWYTQGSKNS-LLAVRQIKSYTGSTFTLDNLGTLXXXXXXXXXXDDSTSIAGDG-G 218 +G N+W T G + L++ RQI+SY +L+ LG + D GD G Sbjct: 157 SGRNLWMTLGGSDPVLISARQIRSY--HQLSLNGLGMVLIQVNVKQMIRDVPKDWGDSVG 214 Query: 219 QLIVVDKGTGRSVYXXXXXXXXXXXXXXVQRPEAYRTVGYSKGTYFVAKTNSSYMDWTYI 278 +++ D+G G VY + Y + + YF++ SSY +W+Y Sbjct: 215 DIMIADQG-GNLVYTAHASAHVPEAAKETLKHPGYDLIKKNGKRYFISYLQSSYQNWSYY 273 Query: 279 NATPFNEMFRQITFVKRLVVIIFGCIXXXXXXXXYRLARSIVRPVSKLTEKMRRIEKGDL 338 N PF++MF +I+F+K ++ F ++A SI P+ +L M+ ++ + Sbjct: 274 NVIPFDQMFAKISFMKTVIGTCFLLFFCVVLLFGRKIANSITEPIEQLVTAMKSVQHSGI 333 Query: 339 DNLEEQALGFVSQTAQDEVSQLNRTFQMMIRRIRELIDENYAKQLVIRETELKALQAQIN 398 + +L + QDE LNR F +M++RI EL++EN KQL+I+ETELKALQAQIN Sbjct: 334 EAGVSLSL---PEHTQDEAGMLNRHFTVMMKRINELMEENVEKQLIIKETELKALQAQIN 390 Query: 399 PHFLYNTLESINWLAKVNKQKQISDMVEALGFLLRSSIGLKDPLISLEKELSIVRSYVII 458 PHFLYNTLESINWLAK N+QKQIS MVE+LGFLLR+SI +K ++++++E IVR Y+ I Sbjct: 391 PHFLYNTLESINWLAKANQQKQISKMVESLGFLLRNSIHMKKDIVTIQEEADIVRHYMTI 450 Query: 459 QRTRFEERLDFRLDVPDGLLDALVPKLTLQPLVENAIRYALEPNIEPCVISISISRTEDG 518 QR RFEERL F LD+ D + L+PKLTLQPL ENAI+YALEP PC I I + + Sbjct: 451 QRFRFEERLKFTLDIDDEVKHCLIPKLTLQPLAENAIQYALEPFTRPCAIRIQAKKAKGC 510 Query: 519 LDLRVSDNGPGMTADFIRGLEQGRI--QTRGEGIGLANIAERIQIVFGQEWGTEIESRPG 576 + + V DNGPGM GRI T G GIGL NI ERI + FG+ +G I S Sbjct: 511 VCITVEDNGPGM---------DGRILESTGGRGIGLWNIRERISLTFGEPYGLRIHSEHE 561 Query: 577 EGTTIHVHIP 586 +GT I + IP Sbjct: 562 KGTRIVITIP 571 >B1DJR5.1 B1DJR5_9BACL Integral membrane sensor signal transduction histidine kinase Length = 586 Score = 392 bits (1006), Expect = e-107, Method: Compositional matrix adjust. Identities = 213/556 (38%), Positives = 310/556 (55%), Gaps = 15/556 (2%) Query: 42 QYVYRIYDRQIYEKASEVLGMSSVSIENELKELEQLSFTVVADEQIQNCLRQLLDNPSPY 101 +Y + YD++IY++++ L +S+ +E EL+ +E++SF + D IQ+ L ++ S Y Sbjct: 38 KYAFHAYDKEIYKQSASALNSASLGVEKELRNMEKISFKIATDSYIQDYLSEIKAGGSEY 97 Query: 102 ERQVLHNRIINRLVAFAGAEKYVYSMILMD------ANDGVMTAGNREWLSETLQDQLRP 155 + I RL+ F EKY+ S +MD N M +RE + + D Sbjct: 98 SNYITAVNIRQRLLTFTSNEKYILSFHVMDVFSKQYGNGYKMINLSRERTDQVVHDTNTQ 157 Query: 156 LAIAGAGSNIWYTQGSKNSLLAVRQIKSYTGSTFTLDNLGTLXXXXXXXXXXDDSTSIAG 215 G + N+L+A R+I+ G LD+LG + D + A Sbjct: 158 FG----GVQFVFPDYGDNALIAGREIRRVDG--LELDHLGNMAVRIDIDRLYSDLVTSAD 211 Query: 216 DGGQLIVVDKGTGRSVYXXXXXXXXXXXXXXVQRPEAYRTVGYSKGTYFVAKTNSSYMDW 275 + + + G VY + + ++ V S +YF+ +S Y+DW Sbjct: 212 NSKAYFAIMQKDGHLVYPHDQPGGMDLTSLQLTGQQGFKIVSLSGKSYFITYYSSGYLDW 271 Query: 276 TYINATPFNEMFRQITFVKRLVVIIFGCIXXXXXXXXYRLARSIVRPVSKLTEKMRRIEK 335 Y+N P++++F K V+I++ + +RSI P+ +L ++M+RI+ Sbjct: 272 VYVNVMPYDQIFHTTESAKNTVIIVYILLSILILGAALSFSRSITGPIERLNQRMKRIQL 331 Query: 336 GDLDNLEEQALGFVSQTAQDEVSQLNRTFQMMIRRIRELIDENYAKQLVIRETELKALQA 395 G + EE A+DE QL R F+MM+ RI ELI+ENY KQL I++TE KALQA Sbjct: 332 GHFEFAEEPE---ERNLAKDEAGQLQRNFRMMVGRIDELINENYVKQLTIKDTEFKALQA 388 Query: 396 QINPHFLYNTLESINWLAKVNKQKQISDMVEALGFLLRSSIGLKDPLISLEKELSIVRSY 455 QINPHFLYNTLESINW AK+ KQIS MVE+LG+LLRS+I K P ++LE EL +V Y Sbjct: 389 QINPHFLYNTLESINWSAKIAGHKQISIMVESLGYLLRSTISHKQPTVTLEDELRLVGHY 448 Query: 456 VIIQRTRFEERLDFRLDVPDGLLDALVPKLTLQPLVENAIRYALEPNIEPCVISISISRT 515 + IQ RFEERL F +PD LL+ VPKL+LQPLVENAI Y LE IE CVI+I+ Sbjct: 449 IAIQHIRFEERLVFENRIPDRLLNMYVPKLSLQPLVENAIHYGLEQMIEACVITITAEEH 508 Query: 516 EDGLDLRVSDNGPGMTADFIRGLEQGRIQTRGEGIGLANIAERIQIVFGQEWGTEIESRP 575 E G+ + V+DNGPG+ D I L G I+ RG GIGL NI +RI+++FG+ +G +ES P Sbjct: 509 EGGIAITVADNGPGLAPDVIDQLRSGEIEPRGTGIGLRNIEDRIKMLFGEAYGIRVESVP 568 Query: 576 GEGTTIHVHIPYVRGE 591 + T I +++P GE Sbjct: 569 QQDTRITLYLPIEMGE 584 >B0NES5.1 B0NES5_EUBSP Putative uncharacterized protein Length = 594 Score = 233 bits (593), Expect = 6e-59, Method: Compositional matrix adjust. Identities = 127/346 (36%), Positives = 192/346 (55%), Gaps = 7/346 (2%) Query: 253 YRTVGYSKGTYFVAKTNSSYMDWTYINATPFNEMFRQITFVKRLVVIIFGCIXXXXXXXX 312 Y + + G YF K + W YI P+ + + F K + +++ Sbjct: 254 YGVISVNAGKYFAVKGSIGNTSWNYICLVPYGHISATLNFTKLMALVVILVSVLISLLLS 313 Query: 313 YRLARSIVRPVSKLTEKMRRIEKGDLDNLEEQALGFVSQTAQDEVSQLNRTFQMMIRRIR 372 L RS+ S+L +KM+ + D G+ DEV L+ F M +I+ Sbjct: 314 RMLIRSVTSDFSRLIQKMKAFGR---DESTPPDTGYDYSGRTDEVGVLHNQFDHMALKIQ 370 Query: 373 ELIDENYAKQLVIRETELKALQAQINPHFLYNTLESINWLAKVNKQKQISDMVEALGFLL 432 LI ENY +++ ++ LKAL+ QINPHFLYNTLE++NW AK +K IS MVE+LG L+ Sbjct: 371 NLIQENYVNEILSKDARLKALENQINPHFLYNTLEAVNWRAKAIGEKDISSMVESLGTLM 430 Query: 433 RSSIGLKDPLISLEKELSIVRSYVIIQRTRFEERLDFRLDVPDGLLDALVPKLTLQPLVE 492 R ++ KD ++ +EL IV+SY+ IQ+ RFE+RL++ + D ++D +P LT+QPLVE Sbjct: 431 RETLNTKDKTFTVRRELEIVKSYLTIQQIRFEDRLEYTKQIDDSIMDISLPHLTIQPLVE 490 Query: 493 NAIRYALEPNIEPCVISISISRTEDGLDLRVSDNGPGMTADFIRGLEQGRIQTRGEGIGL 552 NAI YA+E + E C I I +R+ D + + V +N D +R L+QG + G GIGL Sbjct: 491 NAINYAMEESTEVCHIQIEGTRSGDYVYIDVVNNDSQFEQDLLRKLDQGLVTPHGFGIGL 550 Query: 553 ANIAERIQIVFGQEWGTEIESRPGEGTTIHVHIPYVRGEYRHVQTA 598 NI +RIQ+ +G E+G + ++ E + IP GE HV+T Sbjct: 551 LNIHKRIQLTYGSEYGLHLFNKDDEHAVARIIIP--GGE--HVKTT 592 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.136 0.387 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,007,565,593 Number of extensions: 113880917 Number of successful extensions: 335845 Number of sequences better than 1.0e-05: 2161 Number of HSP's gapped: 333366 Number of HSP's successfully gapped: 2162 Length of query: 601 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 459 Effective length of database: 1,722,912,073 Effective search space: 790816641507 Effective search space used: 790816641507 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)