BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0029.p (1551 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I 1160 0.0 C3H381.1 C3H381_BACTU Polyketide synthase type I 1159 0.0 B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase 1159 0.0 C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I 1157 0.0 C2P7V8.1 C2P7V8_BACCE Polyketide synthase type I 1156 0.0 >C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I Length = 3339 Score = 1160 bits (3001), Expect = 0.0, Method: Compositional matrix adjust. Identities = 613/1526 (40%), Positives = 924/1526 (60%), Gaps = 32/1526 (2%) Query: 9 EIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGY 68 +IA+IG+ R PGA +V+ FW+N+ +G ESI FFT +EL+ESG+ P V P+YV+AKGY Sbjct: 1379 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1438 Query: 69 LENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXAS 128 LE +D FDA FF+Y+P +A +MDPQ+R+FHEC W ALE AGY TYPGLIG + Sbjct: 1439 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1498 Query: 129 LYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTIHL 188 LYWQ LS LSE G F + +KD +ST IS++ NLKGPS+ + T CSTSLV IH Sbjct: 1499 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1558 Query: 189 AAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGAGV 248 A QALL G CDIA+AGG ++T P K+GY YQEGM+ S DGHC+ FDE G + G+G G+ Sbjct: 1559 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1618 Query: 249 VVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNAAS 308 VVLK +EA+ DGD I+AVIKG+AINNDGNRK YTAPSVEGQVEVI+ AQ A V S Sbjct: 1619 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1678 Query: 309 IQFVETHGTGTVLGDPIELEALKAAFGNSEG-VCRIGSVKSNIGHLDAAAGVAGFIKATL 367 I ++ETHGT T LGD IE++AL F ++E IGSVK+N+GHL+AA+GVAG IK Sbjct: 1679 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1738 Query: 368 SLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFGIGGTNAHIV 427 +++ ++LPP+++FT N +I +PF VN +L++ + PLRAGVSSFGIGGTNAHI+ Sbjct: 1739 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGGTNAHII 1798 Query: 428 LEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQVGRT 487 LEEA R Q+++ISAKS+ AL++ + NL ++ +P V LAD +YTLQ+GR Sbjct: 1799 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSYTLQIGRK 1858 Query: 488 DFEHRRFVVANHTGELPEML-QPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQYVD 546 +F+HRR +V + T E E+L QP G R+V V++E+ + F+F G G+QYV+ Sbjct: 1859 EFKHRRALVCSSTQEGIELLNQPEG-------RRVQYVNVKEEHPKVNFLFSGNGSQYVN 1911 Query: 547 MGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQE-ARDEAVYKINRIDINQMVVF 605 MGL LY E +F++ +D CF +L S + +MK +L+P + DEA K+ R++ +Q ++F Sbjct: 1912 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILF 1971 Query: 606 IFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRGQMIKGTEEGA 665 FEYA+ K LM GIKP+ MIGYSFGE+ AACLA VF LEDA++++++RGQ++ G Sbjct: 1972 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2031 Query: 666 MLSVPMTEQELRPLLPP-------DVSLSIVNGPSCVVGGTRTAVEQFEEQLKSLRQICI 718 MLSVP+ E+EL L+ +SL++VNGP+C+V GT A+ FE +LK R +C+ Sbjct: 2032 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKKRLMCM 2091 Query: 719 RLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYWGQQL 778 R+ A HS ++ + D +A + + L P+IP++SNL+G WI EEAT+P YW + + Sbjct: 2092 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2151 Query: 779 TDSIRFADGLKEILKEEALTFLEVGPDRNLSALL-RYFVHRDSSHTILNLIRNPQENVED 837 ++RF+DG++E+ ++ F+E+GP +LS L R + + + I N +R+ Q++V D Sbjct: 2152 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2211 Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-K 896 +L++ + ++W G S++W + Y E+R R+ LP Y F + SY ++GNP+D+ GQ+ Sbjct: 2212 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDL--GQKLN 2269 Query: 897 GKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSGQ 956 K S + K ++ +WFY P W+ L + + + ++F + + + EL++ L + GQ Sbjct: 2270 SKQSKISKNNNISEWFYTPQWKSSTLFEPNHDV-NETWIVFVDQEGLGNELVKDLLNKGQ 2328 Query: 957 RVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPL 1016 RV+ V G F+ ++ + I+PE DY +L +QE +IH+W + N Sbjct: 2329 RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNE-ERQA 2387 Query: 1017 DAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIGL 1076 + Q GFYS+ Y+ Q L + + ++ I ++T+ V V G E L PE + ++G Sbjct: 2388 SIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGT 2447 Query: 1077 GIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPI 1136 +V+PQE ++ +VD+ N D+ ++YRG +R+V Sbjct: 2448 SLVVPQEYSYLSCSSVDV--VLPLNKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQT 2505 Query: 1137 YQPIKLEPQIVKPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPVRPE 1195 Y+P++LE + R NGVY++TGG G IG I+A+HLA +A++ ++ R+ P R E Sbjct: 2506 YEPLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTLQANLVLLTRTGLPNRDE 2565 Query: 1196 WDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECELGAING 1255 WD L E+ S I+++++ E+ G+ + + ADV+D Q+ +AI E + G ING Sbjct: 2566 WDMHL---KENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2622 Query: 1256 VIHCAANMGAEFFNPVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXXXXXXMSSTAAVL 1315 VIH A +G + FN + L++ C F K MSS +AVL Sbjct: 2623 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVL 2682 Query: 1316 XXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTVDXXXXXXXXXXXXGYT--SSIGDLAMS 1373 ++MD + + N++ ++ W +V+ +S+ +L+M+ Sbjct: 2683 GGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWKYWEDEEKDMQIGASVHELSMT 2742 Query: 1374 PEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPRDGQKKRQRPAA 1433 PEEG++A LS ++ ++HSPG L R+ +WV L ++ K + D RP Sbjct: 2743 PEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKE-EELDSTLYHSRPQL 2801 Query: 1434 MVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEETLSLQIP 1493 + EY P N +E++++ IW + ++ +HD+ ELG SL I I S + + ++++P Sbjct: 2802 LTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVP 2861 Query: 1494 IVDLFANPTIAALAKRIGQIENGGQD 1519 I +LF I LA I + + D Sbjct: 2862 IKELFTLSNIEKLANYISRADKSEFD 2887 Score = 551 bits (1421), Expect = e-154, Method: Compositional matrix adjust. Identities = 289/625 (46%), Positives = 393/625 (62%), Gaps = 24/625 (3%) Query: 7 GLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAK 66 GLEIA+IGM+ + PGA +++ FWDNL NG +SI+ FT DEL++ G+ + HP++V+AK Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLEVLQHPNFVKAK 71 Query: 67 GYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXX 126 GYLE + FD SFF Y+P EA++MDPQ+R+ E WEALE AGY P Y GLIG Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 127 ASLYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTI 186 + W + L ++ A + KD +STL S++L LKGPS T+ TACSTSL++I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 187 HLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGA 246 HLA ++LL GEC IA AGG SIT P K+GY+Y EGM SPDG + FD E QG+V +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 247 GVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNA 306 G+V+LKR E+A+ DGD IY VIKGSA NNDG RK YTAPSVEGQ EVIQ A AEV+ Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 307 ASIQFVETHGTGTVLGDPIELEALKAAFG--NSEGVCRIGSVKSNIGHLDAAAGVAGFIK 364 ++I ++ETHGT T LGD IE+EALK AF + + C IGSVKSN+GHLD AAGV G IK Sbjct: 312 STISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 365 ATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNP-LRAGVSSFGIGGTN 423 LS++H+ LPPTL+ N KI+ DSPF +N L + E N LRAGVS+FG GGTN Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTN 431 Query: 424 AHIVLEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQ 483 HIVLEEA R+ +L+++SA+S+ AL + N+ Y+ ++ +V LAD+AYTLQ Sbjct: 432 VHIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTLQ 491 Query: 484 VGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQ 543 GR F +RR V+ + L+ + + K QEN +VF+ P + Sbjct: 492 TGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKT----------QENPDLVFVLPSEYSS 541 Query: 544 YVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYK-INRIDINQM 602 ++ LY+ E LF Q +R ++ D+ ++ +A EA +K + + + Sbjct: 542 IIENVKELYQKEPLFLQVFER--NMTDAQ--------MYTGKALKEAFFKGTDDSLVEDL 591 Query: 603 VVFIFEYALGKYLMELGIKPKYMIG 627 F+ ++ L+E ++P +IG Sbjct: 592 TFFVCLQSIIDVLIECDVRPSNIIG 616 Score = 260 bits (664), Expect = 9e-67, Method: Compositional matrix adjust. Identities = 195/694 (28%), Positives = 318/694 (45%), Gaps = 48/694 (6%) Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQKG 897 Q L LGQ W G I W KLY E R R++LP YPFE++ Y ++ P + Sbjct: 691 QNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWID--PAEQQNITNSE 748 Query: 898 KHSLLPKQPHMEDWFYLPLWQQKAL-PLASGPLGGQLCLLFANDDLISRELLQALRSSGQ 956 + + + K+ ++ WFY P W +K + + G + LLF +++ I L + L G Sbjct: 749 EETSIKKRSNIAKWFYTPGWMEKEIVDVTKG--STKSWLLFLDNEHIGLALKEKLERDGH 806 Query: 957 RVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPL 1016 RVI V G + E+TI P DY QLF LQ+++ + ++HLW+++N+ Sbjct: 807 RVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK----- 861 Query: 1017 DAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIGL 1076 D E+ GFYS+ + + + +F+ + I V+T+ + V G E++ E + L+ Sbjct: 862 DLGI--ETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAP 919 Query: 1077 GIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPI 1136 V PQE +IR +VD + D ++ R R++ I Sbjct: 920 IKVFPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDII-----DTVIAIRNNTRYIRI 974 Query: 1137 YQPI---KLEPQIV--------KPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAI 1185 Y+PI K+ +V K R+ GVY++TGG G +G +AE+LA +A + + Sbjct: 975 YEPIPDEKVSEMLVINENESASKIPNIRSEGVYLITGGIGGVGLKLAEYLARTVKAKLIL 1034 Query: 1186 IQRS-FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIG 1244 + R+ P R EWD+ L E++ + I + + E LGA + ADV+D QM + I Sbjct: 1035 VSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIH 1094 Query: 1245 AIECELGAINGVIHCAANMGAEFFN-PVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXX 1303 E G INGVIH A + + P+ ++ C F PK Sbjct: 1095 QAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLD 1154 Query: 1304 XXXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTV---DXXXXXXXXXXX 1360 +SS + +L +++D++ + +W ++ D Sbjct: 1155 FCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWISINWGDWQYTGTEQVNK 1214 Query: 1361 XGYTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQG---ISEGK 1417 SI L M+ EEG + VL + ++ S G L+KR +W+ L ISE + Sbjct: 1215 IFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISELE 1274 Query: 1418 PVQPRDGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTL 1477 Q + G K R + + +E+ I GIW+EF + ++ ++NFF+LGATSL + Sbjct: 1275 -TQTKTGDKFRNQ-----------DEVEEIIIGIWKEFYSVDTVNENENFFDLGATSLHI 1322 Query: 1478 IRIKSIVEETLSLQIPIVDLFANPTIAALAKRIG 1511 I+I + L I I +F P+I +LAK + Sbjct: 1323 IQIHERLINRLEKHISIGVMFEYPSIRSLAKYLS 1356 >C3H381.1 C3H381_BACTU Polyketide synthase type I Length = 3338 Score = 1159 bits (2998), Expect = 0.0, Method: Compositional matrix adjust. Identities = 615/1526 (40%), Positives = 924/1526 (60%), Gaps = 32/1526 (2%) Query: 9 EIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGY 68 +IA+IG+ R PGA +V+ FW+N+ +G ESI FFT +EL+ESG+ P V P+YV+AKGY Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1437 Query: 69 LENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXAS 128 LE +D FDA FF+Y+P +A +MDPQ+R+FHEC W ALE AGY TYPGLIG + Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 129 LYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTIHL 188 LYWQ LS LSE G F + +KD +ST IS++ NLKGPS+ + T CSTSLV IH Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 189 AAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGAGV 248 A QALL G CDIA+AGG ++T P K+GY YQEGM+ S DGHC+ FDE G + G+G G+ Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 249 VVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNAAS 308 VVLK +EA+ DGD I+AVIKG+AINNDGNRK YTAPSVEGQVEVI+ AQ A V S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 309 IQFVETHGTGTVLGDPIELEALKAAFGNSEG-VCRIGSVKSNIGHLDAAAGVAGFIKATL 367 I ++ETHGT T LGD IE++AL F ++E IGSVK+N+GHL+AA+GVAG IK Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 368 SLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFGIGGTNAHIV 427 +++ ++LPP+++FT N +I +PF VN +L++ + PLRAGVSSFGIGGTNAHI+ Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 428 LEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQVGRT 487 LEEA R Q+++ISAKS+ AL++ + NL Y+ +P V LAD +YTLQ+GR Sbjct: 1798 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNYLEQNPHVNLADASYTLQIGRK 1857 Query: 488 DFEHRRFVVANHTGELPEML-QPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQYVD 546 +F+HRR +V + T E E L QP G R+V + V++E+ I F+F G G+QYV+ Sbjct: 1858 EFKHRRALVCSSTQEGIEQLNQPEG-------RRVQYANVKEEHPKINFLFSGNGSQYVN 1910 Query: 547 MGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQE-ARDEAVYKINRIDINQMVVF 605 MGL LY E +F++ +D CF +L S + +MK +L+P + DEA K+ R++ +Q V+F Sbjct: 1911 MGLELYEQEAIFREAMDECFAILQSITNVNMKEVLYPTTFSIDEATEKLKRMEFSQPVLF 1970 Query: 606 IFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRGQMIKGTEEGA 665 FEY++ K LM GIKP+ MIGYSFGE+ AACLA VF LEDA++++++RGQ++ G Sbjct: 1971 AFEYSVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2030 Query: 666 MLSVPMTEQELRPLLPP-------DVSLSIVNGPSCVVGGTRTAVEQFEEQLKSLRQICI 718 MLSVP+ E+EL L+ +SL++VNGP+C+V GT A+ FE +LK R +C+ Sbjct: 2031 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKKRLMCM 2090 Query: 719 RLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYWGQQL 778 R+ A HS ++ + D +A + + L P+IP++SNL+G WI EEAT+P YW + + Sbjct: 2091 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2150 Query: 779 TDSIRFADGLKEILKEEALTFLEVGPDRNLSALL-RYFVHRDSSHTILNLIRNPQENVED 837 ++RF+DG++E+ ++ F+E+GP +LS L R + + + I N +R+ Q++V D Sbjct: 2151 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2210 Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-K 896 +L++ + ++W G SI+W + Y E+R R+ LP Y F + SY ++GNP+D+ GQ+ Sbjct: 2211 MYFLFSHITRMWVTGISIDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDL--GQKLN 2268 Query: 897 GKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSGQ 956 K S + K ++ +WFY P W+ L + + + ++F + + + EL++ L + GQ Sbjct: 2269 SKQSKISKNNNISEWFYTPQWKSSTLFEPNHDV-NETWIVFVDQEGLGNELVKDLLNKGQ 2327 Query: 957 RVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPL 1016 RV+ V G F+ ++ + I+PE DY +L +QE ++H+W + + Sbjct: 2328 RVVTVETGFAFNKENNDRFIINPEERTDYVKLLDEVQEICGLPTRIVHMWGITDE-ERQA 2386 Query: 1017 DAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIGL 1076 + Q GFYS+ Y+ Q L + + ++ I ++T+ V V G E L PE + ++G Sbjct: 2387 SIEYVNCKQNLGFYSIFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGT 2446 Query: 1077 GIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPI 1136 +V+PQE ++ +VD+ N D+ ++YRG +R+V Sbjct: 2447 SLVVPQEYSYLSCSSVDV--VLPLNKEWKSRLINQLVGECLSNTNDKMIAYRGNKRFVQT 2504 Query: 1137 YQPIKLEPQIVKPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPVRPE 1195 Y+P++LE + R NGVY++TGG G IG I+A+HLA +A++ ++ R+ P R E Sbjct: 2505 YEPLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDE 2564 Query: 1196 WDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECELGAING 1255 WD L E+ S I+++++ E+ G+ + + ADV+D Q+ +AI E E G ING Sbjct: 2565 WDMHL---KENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQEFGKING 2621 Query: 1256 VIHCAANMGAEFFNPVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXXXXXXMSSTAAVL 1315 VIH A +G + FN + L++ C F K MSS +AVL Sbjct: 2622 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVL 2681 Query: 1316 XXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTVDXXXXXXXXXXXXGYT--SSIGDLAMS 1373 ++MD + + N++ ++ W +V+ +S+ +L+M+ Sbjct: 2682 GGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWKYWEDEEKDMQIGASVHELSMT 2741 Query: 1374 PEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPRDGQKKRQRPAA 1433 PEEG++A LS ++ ++HSPG L R+ +WV L ++ K + D RP Sbjct: 2742 PEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKE-EELDSTLYHSRPQL 2800 Query: 1434 MVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEETLSLQIP 1493 + EY P N +E++++ IW + ++ +HD+ ELG SL I I S + + ++++P Sbjct: 2801 LNEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVP 2860 Query: 1494 IVDLFANPTIAALAKRIGQIENGGQD 1519 I +LF I LA I + + D Sbjct: 2861 IKELFTLSNIEKLANYISRADKSEFD 2886 Score = 546 bits (1408), Expect = e-153, Method: Compositional matrix adjust. Identities = 286/625 (45%), Positives = 393/625 (62%), Gaps = 24/625 (3%) Query: 7 GLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAK 66 GLEIA+IGM+ + PGA +++ FWDNL NG +SI+ FT DEL++ G+ + HP++V+AK Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 71 Query: 67 GYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXX 126 GYLE + FD SFF Y+P EA++MDPQ+R+ E WEALE AGY P Y GLIG Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 127 ASLYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTI 186 + W + L ++ A + KD +STL S++L LKGPS T+ TACSTSL++I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 187 HLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGA 246 HLA ++LL GEC IA AGG SIT P K+GY+Y EGM SPDG + FD E QG+V +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 247 GVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNA 306 G+V+LKR E+A+ DGD IY VIKGSA NNDG RK YTAPSVEGQ EVIQ A AEV+ Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 307 ASIQFVETHGTGTVLGDPIELEALKAAFG--NSEGVCRIGSVKSNIGHLDAAAGVAGFIK 364 ++I ++ETHGT T LGD IE+EAL+ AF + + C IGSVKSN+GHLD AAGV G IK Sbjct: 312 STISYIETHGTATPLGDSIEVEALRRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 365 ATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNP-LRAGVSSFGIGGTN 423 LS++H+ LPPTL+ N KI+ DSPF +N L + + N LRAGVS+FG GGTN Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSDDNDLLRAGVSAFGYGGTN 431 Query: 424 AHIVLEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQ 483 HIVLEEA R+ +L+++SA+S+ AL + N+ Y+ ++ +V LAD+AYTLQ Sbjct: 432 VHIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTLQ 491 Query: 484 VGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQ 543 GR F +RR V+ + L+ + + K QEN +VF+ P + Sbjct: 492 TGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKT----------QENPDLVFVLPSEYSS 541 Query: 544 YVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYK-INRIDINQM 602 ++ LY+ E LF + +R ++ D+ ++ +A EA +K + + + Sbjct: 542 IIENVKELYQKEPLFLKVFER--NMTDAQ--------MYTGKALKEAFFKGTDDSLVEDL 591 Query: 603 VVFIFEYALGKYLMELGIKPKYMIG 627 F+ ++ L+E ++P +IG Sbjct: 592 TFFVCLQSIIDVLIECDVRPSNIIG 616 Score = 261 bits (666), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 195/695 (28%), Positives = 319/695 (45%), Gaps = 51/695 (7%) Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-- 895 Q L LGQ W G I W KLY E R R++LP YPFE++ Y + D E Q Sbjct: 691 QNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWI-----DSAEQQNIT 745 Query: 896 KGKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSG 955 + + + K+ ++ +WFY P W +K + + + LLF +++ I L + L G Sbjct: 746 NSEETSIKKRSNIAEWFYTPGWMEKEIVDVTKE-STKSWLLFLDNEHIGLALKEKLERDG 804 Query: 956 QRVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAP 1015 RVI V G + E+TI P DY QLF LQ+++ + ++HLW+++N+ Sbjct: 805 HRVITVGVGPSYKKISLNEFTICPNKQEDYYQLFNELQKQECLPEEIVHLWNVDNK---- 860 Query: 1016 LDAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIG 1075 D E+ GFYS+ + + + +F+ + I V+T+ + V G E++ E + L+ Sbjct: 861 -DLGI--ETLDTGFYSLISLAKTIGKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLA 917 Query: 1076 LGIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVP 1135 V PQE +IR +VD + D ++ R R++ Sbjct: 918 PIKVFPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDII-----DTVIAIRNNTRYIR 972 Query: 1136 IYQPI---KLEPQIV--------KPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIA 1184 IY+PI K+ +V K R+ GVY++TGG G +G +AE+LA +A + Sbjct: 973 IYEPIPDEKVSEMLVINENELASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLI 1032 Query: 1185 IIQRS-FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAI 1243 ++ R+ P R WD+ L E++ + I + + E LGA + ADV+D QM + I Sbjct: 1033 LVSRTALPDREVWDEILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVI 1092 Query: 1244 GAIECELGAINGVIHCAANMGAEFFN-PVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXX 1302 E G INGVIH A + + P+ ++ C F PK Sbjct: 1093 HQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDL 1152 Query: 1303 XXXXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTV---DXXXXXXXXXX 1359 +SS + +L +++D++ + +W ++ D Sbjct: 1153 DFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGAQQVN 1212 Query: 1360 XXGYTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQG---ISEG 1416 SI L M+ EEG + VL + ++ S G L+KR +W+ L ISE Sbjct: 1213 KIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISEL 1272 Query: 1417 KPVQPRDGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLT 1476 + Q + G K R + + +E+ I GIW+EF + +++++NFF+LGATSL Sbjct: 1273 E-TQTKTGDKFRNQ-----------DEVEEIIIGIWKEFYSVDTVNVNENFFDLGATSLH 1320 Query: 1477 LIRIKSIVEETLSLQIPIVDLFANPTIAALAKRIG 1511 +I+I + L QI I +F P+I +LA+ + Sbjct: 1321 IIQIHERLINRLEKQISIGVMFEYPSIRSLARYLS 1355 >B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase Length = 3336 Score = 1159 bits (2998), Expect = 0.0, Method: Compositional matrix adjust. Identities = 613/1526 (40%), Positives = 923/1526 (60%), Gaps = 32/1526 (2%) Query: 9 EIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGY 68 +IA+IG+ R PGA +V+ FW+N+ +G ESI FFT +EL+ESG+ P V P+YV+AKGY Sbjct: 1376 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1435 Query: 69 LENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXAS 128 LE +D FDA FF+Y+P +A +MDPQ+R+FHEC W ALE AGY TYPGLIG + Sbjct: 1436 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1495 Query: 129 LYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTIHL 188 LYWQ LS LSE G F + +KD +ST IS++ NLKGPS+ + T CSTSLV IH Sbjct: 1496 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1555 Query: 189 AAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGAGV 248 A QALL G CDIA+AGG ++T P K+GY YQEGM+ S DGHC+ FDE G + G+G G+ Sbjct: 1556 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1615 Query: 249 VVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNAAS 308 VVLK +EA+ DGD I+AVIKG+AINNDGNRK YTAPSVEGQVEVI+ AQ A V S Sbjct: 1616 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1675 Query: 309 IQFVETHGTGTVLGDPIELEALKAAFGNSEG-VCRIGSVKSNIGHLDAAAGVAGFIKATL 367 I ++ETHGT T LGD IE++AL F ++E IGSVK+N+GHL+AA+GVAG IK Sbjct: 1676 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1735 Query: 368 SLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFGIGGTNAHIV 427 +++ ++LPP+++FT N +I +PF VN +L++ + PLRAGVSSFGIGGTNAHI+ Sbjct: 1736 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGGTNAHII 1795 Query: 428 LEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQVGRT 487 LEEA R Q+++ISAKS+ AL++ + NL ++ +P V LAD +YTLQ+GR Sbjct: 1796 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSYTLQIGRK 1855 Query: 488 DFEHRRFVVANHTGELPEML-QPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQYVD 546 +F+HRR +V + T E E+L QP G R+V V++E+ + F+F G G+QYV+ Sbjct: 1856 EFKHRRALVCSSTQEGIELLNQPEG-------RRVQYVNVKEEHPKVNFLFSGNGSQYVN 1908 Query: 547 MGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQE-ARDEAVYKINRIDINQMVVF 605 MGL LY E +F++ +D CF +L S + +MK +L+P + DEA K+ R++ +Q ++F Sbjct: 1909 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILF 1968 Query: 606 IFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRGQMIKGTEEGA 665 FEYA+ K LM GIKP+ MIGYSFGE+ AACLA VF LEDA++++++RGQ++ G Sbjct: 1969 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2028 Query: 666 MLSVPMTEQELRPLLPP-------DVSLSIVNGPSCVVGGTRTAVEQFEEQLKSLRQICI 718 MLSVP+ E+EL L+ +SL++VNGP+C+V GT A+ FE +LK R +C+ Sbjct: 2029 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2088 Query: 719 RLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYWGQQL 778 R+ A HS ++ + D +A + + L P+IP++SNL+G WI EEAT+P YW + + Sbjct: 2089 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2148 Query: 779 TDSIRFADGLKEILKEEALTFLEVGPDRNLSALL-RYFVHRDSSHTILNLIRNPQENVED 837 ++RF+DG++E+ ++ F+E+GP +LS L R + + + I N +R+ Q++V D Sbjct: 2149 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2208 Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-K 896 +L++ + ++W G S++W + Y E+R R+ LP Y F + SY ++GNP+D+ GQ+ Sbjct: 2209 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDL--GQKLN 2266 Query: 897 GKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSGQ 956 K S + K ++ +WFY P W+ L + + + ++F + + + EL++ L + GQ Sbjct: 2267 SKQSKISKNNNISEWFYTPQWKSSTLFEPNHDV-NETWIVFVDQEGLGNELVKDLLNKGQ 2325 Query: 957 RVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPL 1016 RV+ V G F+ ++ + I+PE DY +L +QE +IH+W + N Sbjct: 2326 RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNE-ERQA 2384 Query: 1017 DAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIGL 1076 + Q GFYS+ Y+ Q L + + ++ I ++T+ V V G E L PE + ++G Sbjct: 2385 SIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGT 2444 Query: 1077 GIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPI 1136 +V+PQE ++ +VD+ N D+ ++YRG +R+V Sbjct: 2445 SLVVPQEYSYLSCSSVDV--VLPLNKEWKSRLINQLVEECLSNTNDKMIAYRGNKRFVQT 2502 Query: 1137 YQPIKLEPQIVKPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPVRPE 1195 Y+P++LE + R NGVY++TGG G IG I+A+HLA +A++ ++ R+ P R E Sbjct: 2503 YEPLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDE 2562 Query: 1196 WDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECELGAING 1255 WD L E+ S I+++++ E+ G+ + + ADV+D Q+ +AI E + G ING Sbjct: 2563 WDMHL---KENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2619 Query: 1256 VIHCAANMGAEFFNPVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXXXXXXMSSTAAVL 1315 VIH A +G + FN + L++ C F K MSS +AVL Sbjct: 2620 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVL 2679 Query: 1316 XXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTVDXXXXXXXXXXXXGYT--SSIGDLAMS 1373 ++MD + + N++ + W +V+ +S+ +L+M+ Sbjct: 2680 GGLGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWKYWEDEEKDMQIGASVHELSMT 2739 Query: 1374 PEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPRDGQKKRQRPAA 1433 PEEG++A LS ++ ++HSPG L R+ +WV L ++ K + D RP Sbjct: 2740 PEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKE-EELDSTLYHSRPQL 2798 Query: 1434 MVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEETLSLQIP 1493 + EY P N +E++++ IW + ++ +HD+ ELG SL I I S + + ++++P Sbjct: 2799 LTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVP 2858 Query: 1494 IVDLFANPTIAALAKRIGQIENGGQD 1519 I +LF I LA I + + D Sbjct: 2859 IKELFTLSNIEKLANYISRADKSEFD 2884 Score = 547 bits (1410), Expect = e-153, Method: Compositional matrix adjust. Identities = 288/625 (46%), Positives = 392/625 (62%), Gaps = 24/625 (3%) Query: 7 GLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAK 66 GLEIA+IGM+ + PGA +++ FWDNL NG +SI+ FT DEL++ G+ + HP++V+AK Sbjct: 10 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 69 Query: 67 GYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXX 126 GYLE + FD SFF Y+P EA++MDPQ+R+ E WEALE AGY P Y GLIG Sbjct: 70 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 129 Query: 127 ASLYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTI 186 + W + L ++ A + KD +STL S++L LKGPS T+ TACSTSL++I Sbjct: 130 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 189 Query: 187 HLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGA 246 HLA ++LL GEC IA AGG SIT P K+GY+Y EGM SPDG + FD E QG+V +G Sbjct: 190 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 249 Query: 247 GVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNA 306 G+V+LKR E+A+ DGD IY VIKGSA NNDG RK YTAPSVEGQ EVIQ A AEV+ Sbjct: 250 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 309 Query: 307 ASIQFVETHGTGTVLGDPIELEALKAAFG--NSEGVCRIGSVKSNIGHLDAAAGVAGFIK 364 ++I +VETHGT T LGD IE+EALK AF + + C IGSVKSN+GHLD AAGV G IK Sbjct: 310 STISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 369 Query: 365 ATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNP-LRAGVSSFGIGGTN 423 LS++H+ LPPTL+ N KI+ DSPF +N L + E LRAGVS+FG GGTN Sbjct: 370 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDKDLLRAGVSAFGYGGTN 429 Query: 424 AHIVLEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQ 483 HIVLEEA R+ +L+++SA+S+ AL + N+ Y+ ++ +V LAD+AYTLQ Sbjct: 430 VHIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELADVAYTLQ 489 Query: 484 VGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQ 543 GR F +RR V+ + L+ + + K QEN +VF+ P + Sbjct: 490 TGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKT----------QENPDLVFVLPSEYSS 539 Query: 544 YVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYK-INRIDINQM 602 ++ LY+ E LF + +R ++ D+ ++ +A EA +K + + + Sbjct: 540 IIENVKELYQKEPLFLKVFER--NMTDAQ--------MYTGKALKEAFFKGTDDSLVEDL 589 Query: 603 VVFIFEYALGKYLMELGIKPKYMIG 627 F+ ++ L+E ++P +IG Sbjct: 590 TFFVCLQSIIDVLIECDVRPSNIIG 614 Score = 262 bits (669), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 197/696 (28%), Positives = 320/696 (45%), Gaps = 53/696 (7%) Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-- 895 Q L LGQ W G I W KLY E R R++LP YPFE++ Y + D E Q Sbjct: 689 QNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWI-----DPAEQQNIT 743 Query: 896 KGKHSLLPKQPHMEDWFYLPLWQQKAL-PLASGPLGGQLCLLFANDDLISRELLQALRSS 954 + + + K+ ++ +WFY P W +K + + G + LLF +++ I L + L Sbjct: 744 NSEETSIKKRSNIAEWFYTPGWMEKEIVDVIKG--STKSWLLFLDNEHIGLALKEKLERD 801 Query: 955 GQRVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSA 1014 G RVI V G + E+TI P DY QLF LQ+++ + ++HLW+++N+ Sbjct: 802 GHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK--- 858 Query: 1015 PLDAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLI 1074 D E+ GFYS+ + + + +F+ + I V+T+ + V G E++ E + L+ Sbjct: 859 --DLGI--ETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLL 914 Query: 1075 GLGIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWV 1134 V PQE +IR +VD + D ++ R R++ Sbjct: 915 APIKVFPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDII-----DTVIAIRNNTRYI 969 Query: 1135 PIYQPI---KLEPQIV--------KPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASI 1183 IY+PI K+ +V K R+ GVY++TGG G +G +AE+LA +A + Sbjct: 970 RIYEPIPDEKVSEMLVIKENESASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKL 1029 Query: 1184 AIIQRS-FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADA 1242 ++ R+ P R EWD+ L E++ + I + + E LGA + ADV+D QM + Sbjct: 1030 ILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNV 1089 Query: 1243 IGAIECELGAINGVIHCAANMGAEFFN-PVTRLDEALCRTIFQPKXXXXXXXXXXXXXXX 1301 I E G INGVIH A + + P+ ++ C F PK Sbjct: 1090 IHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYD 1149 Query: 1302 XXXXXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTV---DXXXXXXXXX 1358 +SS + +L +++D++ + +W ++ D Sbjct: 1150 LDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGTEQV 1209 Query: 1359 XXXGYTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQG---ISE 1415 SI L M+ EEG + VL + ++ S G L+KR +W+ L ISE Sbjct: 1210 NKIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISE 1269 Query: 1416 GKPVQPRDGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSL 1475 + Q + G K R + + +E+ I GIW+EF + +++++NFF+LGATSL Sbjct: 1270 LE-TQTKTGDKFRNQ-----------DEVEEIIIGIWKEFYSVDTVNVNENFFDLGATSL 1317 Query: 1476 TLIRIKSIVEETLSLQIPIVDLFANPTIAALAKRIG 1511 +I+I + L I I +F P+I +LAK + Sbjct: 1318 HIIQIHERLINRLEKHISIGVMFEYPSIHSLAKYLS 1353 >C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I Length = 3338 Score = 1157 bits (2994), Expect = 0.0, Method: Compositional matrix adjust. Identities = 614/1526 (40%), Positives = 923/1526 (60%), Gaps = 32/1526 (2%) Query: 9 EIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGY 68 +IA+IG+ R PGA +V+ FW+N+ +G ESI FFT +EL+ESG+ P V P+YV+AKGY Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1437 Query: 69 LENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXAS 128 LE +D FDA FF+Y+P +A +MDPQ+R+FHEC W ALE AGY TYPGLIG + Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 129 LYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTIHL 188 LYWQ LS LSE G F + +KD +ST IS++ NLKGPS+ + T CSTSLV IH Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 189 AAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGAGV 248 A QALL G CDIA+AGG ++T P K+GY YQEGM+ S DGHC+ FDE G + G+G G+ Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 249 VVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNAAS 308 VVLK +EA+ DGD I+AVIKG+AINNDGNRK YTAPSVEGQVEVI+ AQ A V S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 309 IQFVETHGTGTVLGDPIELEALKAAFGNSEG-VCRIGSVKSNIGHLDAAAGVAGFIKATL 367 I ++ETHGT T LGD IE++AL F ++E IGSVK+N+GHL+AA+GVAG IK Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 368 SLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFGIGGTNAHIV 427 +++ ++LPP+++FT N +I +PF VN +L++ + PLRAGVSSFGIGGTNAHI+ Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 428 LEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQVGRT 487 LEEA R Q+++ISAKS+ AL++ + NL ++ +P V LAD +YTLQ+GR Sbjct: 1798 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGRK 1857 Query: 488 DFEHRRFVVANHTGELPEML-QPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQYVD 546 +F+HRR +V + T E E L QP G R+V + V++E+ I F+F G G+QYV+ Sbjct: 1858 EFKHRRALVCSSTQEGIEQLNQPDG-------RRVQYANVKEEHPKIHFLFSGNGSQYVN 1910 Query: 547 MGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQE-ARDEAVYKINRIDINQMVVF 605 MGL LY E +F++ +D CF +L S + +MK +L+P + +EA K+ R++ +Q ++F Sbjct: 1911 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILF 1970 Query: 606 IFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRGQMIKGTEEGA 665 FEYA+ K LM GIKP+ MIGYSFGE+ AACLA VF LEDA++++++RGQ++ G Sbjct: 1971 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2030 Query: 666 MLSVPMTEQELRPLLPP-------DVSLSIVNGPSCVVGGTRTAVEQFEEQLKSLRQICI 718 MLSVP+ E+EL L+ +SL++VNGP+C+V GT A+ FE +LK R +C+ Sbjct: 2031 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2090 Query: 719 RLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYWGQQL 778 R+ A HS ++ + D +A + + L P+IP++SNL+G WI EEAT+P YW + + Sbjct: 2091 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2150 Query: 779 TDSIRFADGLKEILKEEALTFLEVGPDRNLSALL-RYFVHRDSSHTILNLIRNPQENVED 837 ++RF+DG++E+ ++ F+E+GP +LS L R + + + I N +R+ Q++V D Sbjct: 2151 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2210 Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-K 896 +L++ + ++W G S++W + Y E+R R+ LP Y F + SY ++GNP+D+ GQ+ Sbjct: 2211 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDL--GQKLN 2268 Query: 897 GKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSGQ 956 K S + K ++ +WFY P W+ L + + + ++F + + + EL++ L + GQ Sbjct: 2269 SKQSKISKNNNISEWFYTPQWKSSTLFEPNHDV-NETWIVFVDQEGLGNELVKDLLNKGQ 2327 Query: 957 RVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPL 1016 RV+ V G F+ ++ + I+PE DY +L +QE +IH+W + N Sbjct: 2328 RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNE-ERQA 2386 Query: 1017 DAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIGL 1076 + Q GFYS+ Y+ Q L + + ++ I ++T+ V V G E L PE + ++G Sbjct: 2387 SIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGT 2446 Query: 1077 GIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPI 1136 +V+PQE ++ +VD+ N D+ ++YRG +R+V Sbjct: 2447 SLVVPQEYSYLSCSSVDV--VLPLNKEGKSRLINQLIEECLSNTNDKMIAYRGNKRFVQT 2504 Query: 1137 YQPIKLEPQIVKPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPVRPE 1195 Y+P++LE + R NGVY++TGG G IG I+A+HLA +A+I ++ R+ P R E Sbjct: 2505 YEPLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANIVLLTRTGLPNRDE 2564 Query: 1196 WDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECELGAING 1255 WD L E+ S I+++++ E+ G+ + + ADV+D Q+ +AI E + G ING Sbjct: 2565 WDMHL---KENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2621 Query: 1256 VIHCAANMGAEFFNPVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXXXXXXMSSTAAVL 1315 VIH A +G + FN + L++ C F K MSS +AVL Sbjct: 2622 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVL 2681 Query: 1316 XXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTVDXXXXXXXXXXXXGYT--SSIGDLAMS 1373 ++MD + + N++ + W +V+ +S+ +L+M+ Sbjct: 2682 GGLGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWKYWEDEEKDMQIGASVHELSMT 2741 Query: 1374 PEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPRDGQKKRQRPAA 1433 PEEG++A LS ++ ++HSPG L R+ +WV L ++ K + D RP Sbjct: 2742 PEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKE-EELDSTLYHSRPQL 2800 Query: 1434 MVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEETLSLQIP 1493 + EY P N +E++++ IW + ++ +HD+ ELG SL I I S + + ++++P Sbjct: 2801 LTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVP 2860 Query: 1494 IVDLFANPTIAALAKRIGQIENGGQD 1519 I +LF I LA I + + D Sbjct: 2861 IKELFTLSNIEKLANYISRADKSEFD 2886 Score = 550 bits (1416), Expect = e-154, Method: Compositional matrix adjust. Identities = 288/625 (46%), Positives = 393/625 (62%), Gaps = 24/625 (3%) Query: 7 GLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAK 66 GLEIA+IGM+ + PGA +++ FWDNL NG +SI+ FT DEL++ G+ + HP++V+AK Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 71 Query: 67 GYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXX 126 GYLE + FD SFF Y+P EA++MDPQ+R+ E WEALE AGY P Y GLIG Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 127 ASLYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTI 186 + W + L ++ A + KD +STL S++L LKGPS T+ TACSTSL++I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 187 HLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGA 246 HLA ++LL GEC IA AGG SIT P K+GY+Y EGM SPDG + FD E QG+V +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 247 GVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNA 306 G+V+LKR E+A+ DGD IY VIKGSA NNDG RK YTAPSVEGQ EVIQ A AEV+ Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 307 ASIQFVETHGTGTVLGDPIELEALKAAFG--NSEGVCRIGSVKSNIGHLDAAAGVAGFIK 364 ++I ++ETHGT T LGD IE+EALK AF + + C IGSVKSN+GHLD AAGV G IK Sbjct: 312 STISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 365 ATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNP-LRAGVSSFGIGGTN 423 LS++H+ LPPTL+ N KI+ DSPF +N L + E N LRAGVS+FG GGTN Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTN 431 Query: 424 AHIVLEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQ 483 HIVLEEA R+ +L+++SA+S+ AL + N+ Y+ ++ +V LAD+AYTLQ Sbjct: 432 VHIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTLQ 491 Query: 484 VGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQ 543 GR F +RR V+ + L+ + + K QEN +VF+ P + Sbjct: 492 TGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKT----------QENPDLVFVLPSEYSS 541 Query: 544 YVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYK-INRIDINQM 602 ++ LY+ E LF + +R ++ D+ ++ +A EA +K + + + Sbjct: 542 IIENVKELYQKEPLFLKVFER--NMTDAQ--------MYTGKALKEAFFKGTDDSLVEDL 591 Query: 603 VVFIFEYALGKYLMELGIKPKYMIG 627 F+ ++ L+E ++P +IG Sbjct: 592 TFFVCLQSIIDVLIECDVRPSNIIG 616 Score = 264 bits (674), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 195/695 (28%), Positives = 320/695 (46%), Gaps = 51/695 (7%) Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-- 895 Q L LGQ W G I W KLY E R R++LP YPFE++ Y + D E Q Sbjct: 691 QNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWI-----DPAEQQNIT 745 Query: 896 KGKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSG 955 + + + K+ ++ +WFY P W +K + + + LLF +++ I L + L G Sbjct: 746 NSEETSIKKRSNIAEWFYTPGWMEKEIVDVTKE-STKSWLLFLDNEHIGLALKEKLERDG 804 Query: 956 QRVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAP 1015 RVI V G + E+TI P DY QLF LQ+++ + ++HLW+++N+ Sbjct: 805 HRVITVGVGPSYKKISLNEFTICPTKQEDYYQLFNELQKQECLPEEIVHLWNVDNK---- 860 Query: 1016 LDAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIG 1075 D E+ GFYS+ + + + +F+ + I V+T+ + V G E++ E + L+ Sbjct: 861 -DLGI--ETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLA 917 Query: 1076 LGIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVP 1135 V PQE +IR +VD + D ++ R R++ Sbjct: 918 PIKVFPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDII-----DTVIAIRNNTRYIR 972 Query: 1136 IYQPI---KLEPQIV--------KPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIA 1184 IY+PI K+ +V K R+ G+Y++TGG G +G +AE+LA +A + Sbjct: 973 IYEPIPDEKVSEMLVINENELASKIPNIRSEGIYLITGGMGGVGLKLAEYLARTVKAKLI 1032 Query: 1185 IIQRS-FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAI 1243 ++ R+ P R EWD+ L E++ + I + + E LGA + ADV+D QM + I Sbjct: 1033 LVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVI 1092 Query: 1244 GAIECELGAINGVIHCAANMGAEFFN-PVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXX 1302 E G INGVIH A + + P+ ++ C F PK Sbjct: 1093 HQTEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDL 1152 Query: 1303 XXXXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTV---DXXXXXXXXXX 1359 +SS + +L +++D++ + +W ++ D Sbjct: 1153 DFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGAQQVN 1212 Query: 1360 XXGYTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQG---ISEG 1416 SI L M+ EEG + VL + ++ S G L+KR +W+ L ISE Sbjct: 1213 KIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISEL 1272 Query: 1417 KPVQPRDGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLT 1476 + Q + G K R + + +E+ I GIW+EF + +++++NFF+LGATSL Sbjct: 1273 E-TQTKTGDKFRNQ-----------DEVEEIIIGIWKEFYSVDTVNVNENFFDLGATSLH 1320 Query: 1477 LIRIKSIVEETLSLQIPIVDLFANPTIAALAKRIG 1511 +I+I + L QI I +F P+I +LA+ + Sbjct: 1321 IIQIHERLINRLEKQISIGVMFEYPSIRSLARYLS 1355 >C2P7V8.1 C2P7V8_BACCE Polyketide synthase type I Length = 3338 Score = 1156 bits (2991), Expect = 0.0, Method: Compositional matrix adjust. Identities = 613/1526 (40%), Positives = 925/1526 (60%), Gaps = 32/1526 (2%) Query: 9 EIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAKGY 68 +IA+IG+ R PGA +V+ FW+N+ +G ESI FFT +EL+ESG+ P V+ P+YV+AKGY Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVNSPNYVKAKGY 1437 Query: 69 LENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXXAS 128 LE +D FDA FF+Y+P +A +MDPQ+R+FHEC W ALE AGY TYPGLIG + Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 129 LYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTIHL 188 LYWQ LS LSE G F + +KD +ST IS++ NLKGPS+ + T CSTSLV IH Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 189 AAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGAGV 248 A QALL G CDIA+AGG ++T P K+GY YQEGM+ S DGHC+ FDE G + G+G G+ Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 249 VVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNAAS 308 VVLK +EA+ DGD I+AVIKG+AINNDGNRK YTAPSVEGQVEVI+ AQ A V S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 309 IQFVETHGTGTVLGDPIELEALKAAFGNSEG-VCRIGSVKSNIGHLDAAAGVAGFIKATL 367 I ++ETHGT T LGD IE++AL F ++E IGSVK+N+GHL+AA+GVAG IK Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 368 SLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNPLRAGVSSFGIGGTNAHIV 427 +++ ++LPP+++FT N +I +PF VN +L++ + PLRAGVSSFGIGGTNAHI+ Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 428 LEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQVGRT 487 LEEA R Q+++ISAKS+ AL++ + NL ++ +P V LAD +YTLQ+GR Sbjct: 1798 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGRK 1857 Query: 488 DFEHRRFVVANHTGELPEML-QPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQYVD 546 +F+HRR +V + T E E L QP G R+V + V++E+ I F+F G G+QYV+ Sbjct: 1858 EFKHRRALVCSSTQEGIEQLNQPDG-------RRVQYANVKEEHPKIHFLFSGNGSQYVN 1910 Query: 547 MGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQE-ARDEAVYKINRIDINQMVVF 605 MGL LY E +F++ +D CF +L S + +MK +L+P + +EA K+ R++ +Q ++F Sbjct: 1911 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILF 1970 Query: 606 IFEYALGKYLMELGIKPKYMIGYSFGEFAAACLAGVFVLEDAIRVIIRRGQMIKGTEEGA 665 FEYA+ K LM GIKP+ MIGYSFGE+ AACLA VF LEDA++++++RGQ++ G Sbjct: 1971 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2030 Query: 666 MLSVPMTEQELRPLLPP-------DVSLSIVNGPSCVVGGTRTAVEQFEEQLKSLRQICI 718 MLSVP+ E+EL L+ +SL++VNGP+C+V GT A+ FE +LK R +C+ Sbjct: 2031 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2090 Query: 719 RLDTSYALHSAVMEPVRDAFAEEMKQIRLYPPQIPFISNLSGNWITDEEATDPGYWGQQL 778 R+ A HS ++ + D +A + + L P+IP++SNL+G WI EEAT+P YW + + Sbjct: 2091 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2150 Query: 779 TDSIRFADGLKEILKEEALTFLEVGPDRNLSALL-RYFVHRDSSHTILNLIRNPQENVED 837 ++RF+DG++E+ ++ F+E+GP +LS L R + + + I N +R+ Q++V D Sbjct: 2151 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2210 Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-K 896 +L++ + ++W G S++W + Y E+R R+ LP Y F + SY ++GNP+D+ GQ+ Sbjct: 2211 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDL--GQKLN 2268 Query: 897 GKHSLLPKQPHMEDWFYLPLWQQKALPLASGPLGGQLCLLFANDDLISRELLQALRSSGQ 956 K S + K ++ +WFY P W+ L + + + ++F + + + EL++ L + GQ Sbjct: 2269 SKQSKISKNNNISEWFYTPQWKSSTLFEPNHDV-NETWIVFVDQEGLGNELVKDLLNKGQ 2327 Query: 957 RVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSAPL 1016 RV+ V G F+ ++ + I+PE DY +L +QE +IH+W + N Sbjct: 2328 RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNE-ERQA 2386 Query: 1017 DAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLIGL 1076 + Q GFYS+ Y+ Q L + + ++ I ++T+ V V G E L PE + ++G Sbjct: 2387 SIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGT 2446 Query: 1077 GIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWVPI 1136 +V+PQE ++ +VD+ N D+ ++YRG +R+V Sbjct: 2447 SLVVPQEYSYLSCSSVDV--VLPLNKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQT 2504 Query: 1137 YQPIKLEPQIVKPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASIAIIQRS-FPVRPE 1195 Y+P++LE + R NGVY++TGG G IG I+A+HLA +A++ ++ R+ P R E Sbjct: 2505 YEPLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDE 2564 Query: 1196 WDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADAIGAIECELGAING 1255 WD L E+ S I+++++ E+ G+ + + ADV+D Q+ +AI E + G ING Sbjct: 2565 WDMHL---KENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2621 Query: 1256 VIHCAANMGAEFFNPVTRLDEALCRTIFQPKXXXXXXXXXXXXXXXXXXXXXMSSTAAVL 1315 VIH A +G + FN + L++ C F K MSS +AVL Sbjct: 2622 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLINLEECLRNKDLDFCVLMSSISAVL 2681 Query: 1316 XXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTVDXXXXXXXXXXXXGYT--SSIGDLAMS 1373 ++MD + + N++ ++ W +V+ +S+ +L+M+ Sbjct: 2682 GGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWKYWEDEEKDMQIGASVHELSMT 2741 Query: 1374 PEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQGISEGKPVQPRDGQKKRQRPAA 1433 PEEG++A LS ++ ++HSPG L R+ +WV L ++ K + D RP Sbjct: 2742 PEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKE-EELDSTLYHSRPQL 2800 Query: 1434 MVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSLTLIRIKSIVEETLSLQIP 1493 + EY P N +E++++ IW + ++ +HD+ ELG SL I I S + + ++++P Sbjct: 2801 LTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFNVEVP 2860 Query: 1494 IVDLFANPTIAALAKRIGQIENGGQD 1519 I +LF I LA I + + D Sbjct: 2861 IKELFTLSNIEKLANYISRADKSEFD 2886 Score = 551 bits (1420), Expect = e-154, Method: Compositional matrix adjust. Identities = 290/625 (46%), Positives = 393/625 (62%), Gaps = 24/625 (3%) Query: 7 GLEIAVIGMSARVPGAADVHTFWDNLVNGKESITFFTADELLESGIEPAAVSHPDYVRAK 66 GLEIA+IGM+ + PGA +++ FWDNL NG +SI+ FT DEL++ G+ + HP++V+AK Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 71 Query: 67 GYLENSDQFDASFFNYSPLEAEVMDPQVRIFHECVWEALEDAGYCPGTYPGLIGXXXXXX 126 GYLE + FD SFF Y+P EA++MDPQ+R+ E WEALE AGY P Y GLIG Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 127 ASLYWQALSYLSEGARLLGPFTANQFANKDYMSTLISHRLNLKGPSLTVNTACSTSLVTI 186 + W + L ++ A + KD +STL S++L LKGPS T+ TACSTSL++I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 187 HLAAQALLNGECDIALAGGASITLPLKSGYQYQEGMILSPDGHCKAFDEEGQGSVPGNGA 246 HLA ++LL GEC IA AGG SIT P K+GY+Y EGM SPDG + FD E QG+V +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 247 GVVVLKRFEEAVQDGDHIYAVIKGSAINNDGNRKSAYTAPSVEGQVEVIQTAQQLAEVNA 306 G+V+LKR E+A+ DGD IY VIKGSA NNDG RK YTAPSVEGQ EVIQ A AEV+ Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 307 ASIQFVETHGTGTVLGDPIELEALKAAFG--NSEGVCRIGSVKSNIGHLDAAAGVAGFIK 364 ++I ++ETHGT T LGD IE+EALK AF + + C IGSVKSN+GHLD AAGV G IK Sbjct: 312 STISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 365 ATLSLQHRLLPPTLHFTTLNPKINLADSPFVVNGKLSDLSGEGNP-LRAGVSSFGIGGTN 423 LS++H+ LPPTL+ N KI+ DSPF +N L + E N LRAGVS+FG GGTN Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTN 431 Query: 424 AHIVLEEAXXXXXXXXGRDSQLILISAKSRSALEQHSSNLAAYIRNHPEVPLADLAYTLQ 483 HIVLEEA R+ +L+++SA+S+ AL + NL Y+ ++ +V LAD+AYTLQ Sbjct: 432 VHIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNLVQYLESNKDVELADVAYTLQ 491 Query: 484 VGRTDFEHRRFVVANHTGELPEMLQPLGNEKGKPSRKVFTSTVEQENKPIVFMFPGLGNQ 543 GR F +RR V+ + L+ + + K QEN +VF+ P + Sbjct: 492 TGRRPFTYRRAVLCKDIDSAIDNLKTVKDFHVKT----------QENPELVFVLPSEYSS 541 Query: 544 YVDMGLGLYRTELLFKQELDRCFDLLDSHLDFSMKAILFPQEARDEAVYK-INRIDINQM 602 ++ LY+ E LF Q +R ++ D+ ++ +A EA +K + + + Sbjct: 542 IIENVKELYQKEPLFLQVFER--NMTDAQ--------MYTGKALKEAFFKGTDDSLVEDL 591 Query: 603 VVFIFEYALGKYLMELGIKPKYMIG 627 F+ ++ L+E ++P +IG Sbjct: 592 TFFVCLQSIIDVLIECDVRPSNIIG 616 Score = 264 bits (675), Expect = 5e-68, Method: Compositional matrix adjust. Identities = 198/696 (28%), Positives = 321/696 (46%), Gaps = 53/696 (7%) Query: 838 QTYLYTRLGQLWGAGHSIEWMKLYAYERRNRLSLPAYPFERESYGMEGNPFDMLEGQQ-- 895 Q L LGQ W G I W KLY E R R++LP YPFE++ Y + D E Q Sbjct: 691 QNDLLELLGQAWELGVEINWSKLYEEEFRLRIALPTYPFEKKRYWI-----DPAEQQNII 745 Query: 896 KGKHSLLPKQPHMEDWFYLPLWQQKAL-PLASGPLGGQLCLLFANDDLISRELLQALRSS 954 + + + K+ ++ +WFY P W +K + + G + LLF +++ I L + L Sbjct: 746 NSEETSIKKRSNIAEWFYTPGWMEKEIVDVTKG--STKSWLLFLDNEHIGLALKEKLERD 803 Query: 955 GQRVIPVYRGHEFSMHDDGEYTIHPESLADYQQLFAVLQEKQVEADNLIHLWSLENRVSA 1014 G RVI V G + E+TI P DY QLF LQ+++ + ++HLW+++N+ Sbjct: 804 GHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK--- 860 Query: 1015 PLDAAAFHESQKNGFYSVTYIVQCLHQFSRNKAVRIAVVTDEVFPVTGQETLHPENAPLI 1074 D E+ GFYS+ + + + +F+ + I V+T+ + V G E++ E + L+ Sbjct: 861 --DLGI--ETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLL 916 Query: 1075 GLGIVIPQEMQHIRHLTVDIQAASAANXXXXXXXXXXXXXXXXXXHRDRQVSYRGLQRWV 1134 V PQE +IR +VD + D ++ R R++ Sbjct: 917 APIKVFPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQADII-----DTVIAIRNNTRYI 971 Query: 1135 PIYQPI---KLEPQIV--------KPDLFRTNGVYVLTGGAGMIGWIIAEHLAINYRASI 1183 IY+PI K+ +V K R+ GVY++TGG G +G +AE+LA +A + Sbjct: 972 RIYEPIPDEKVSEMLVINENESASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKL 1031 Query: 1184 AIIQRS-FPVRPEWDKWLGDHPEDDSTSRTIQEMIQAEKLGANIAIYPADVSDYGQMADA 1242 ++ R+ P R EWD+ L E++ + I + + E LGA + ADV+D QM + Sbjct: 1032 ILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNV 1091 Query: 1243 IGAIECELGAINGVIHCAANMGAEFFN-PVTRLDEALCRTIFQPKXXXXXXXXXXXXXXX 1301 I E G INGVIH A + + P+ ++ C F PK Sbjct: 1092 IHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYD 1151 Query: 1302 XXXXXXMSSTAAVLXXXXXXXXXXXXVFMDTYMKIRNKHRQVKWKTV---DXXXXXXXXX 1358 +SS + +L +++D++ + +W ++ D Sbjct: 1152 LDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGTEQV 1211 Query: 1359 XXXGYTSSIGDLAMSPEEGIEALTRVLSAERYHHMVHSPGILDKRLAEWVQLQG---ISE 1415 SI L M+ EEG + VL + ++ S G L+KR +W+ L ISE Sbjct: 1212 NKIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISE 1271 Query: 1416 GKPVQPRDGQKKRQRPAAMVEYEKPSNHLEKQIAGIWEEFLGIRDISIHDNFFELGATSL 1475 + Q + G K R + + +E+ I GIW+EF + +++++NFF+LGATSL Sbjct: 1272 LE-TQTKTGDKFRNQ-----------DEVEEVIIGIWKEFYSVDTVNVNENFFDLGATSL 1319 Query: 1476 TLIRIKSIVEETLSLQIPIVDLFANPTIAALAKRIG 1511 +I+I + L QI I +F P+I +LAK + Sbjct: 1320 HIIQIHERLINRLEKQISIGVMFEYPSIRSLAKYLS 1355 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 8,903,145,893 Number of extensions: 376954907 Number of successful extensions: 934651 Number of sequences better than 1.0e-05: 12431 Number of HSP's gapped: 879275 Number of HSP's successfully gapped: 15486 Length of query: 1551 Length of database: 3,060,696,203 Length adjustment: 149 Effective length of query: 1402 Effective length of database: 1,656,964,968 Effective search space: 2323064885136 Effective search space used: 2323064885136 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 138 (57.8 bits)