BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0028.p (2184 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase 737 0.0 C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I 706 0.0 C2P7V8.1 C2P7V8_BACCE Polyketide synthase type I 701 0.0 C0JRE5.1 C0JRE5_BACCE ZmaA 701 0.0 C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I 701 0.0 >B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase Length = 3336 Score = 737 bits (1902), Expect = 0.0, Method: Compositional matrix adjust. Identities = 456/1279 (35%), Positives = 670/1279 (52%), Gaps = 101/1279 (7%) Query: 2 KENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKE 61 +++++TGLE+AIIGM+G FPGA + QF+ N+KNGVDSIS FT+++L + GV +V Sbjct: 4 QDDSKTGLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHP 63 Query: 62 NFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIG 121 NFVKAKGYL E EYFD SFF YTP EA+ MDPQ R+L E W ALE AGY P + IG Sbjct: 64 NFVKAKGYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIG 123 Query: 122 VYAGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACS 181 +Y G +F+W + + S + E E L+ KD +ST SYKL LKGPS+TL+TACS Sbjct: 124 LYVGASTNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACS 183 Query: 182 TSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGT 241 TSL+++H AC+ +++GEC +A AGGVS+T P +NGY + +GM S DG+ R FDA + G Sbjct: 184 TSLLSIHLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGA 243 Query: 242 VVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHR 301 V +G+G+VILKRLEDA+ D D IY VIKG+A NNDG RKVGY+APSV+GQAEVI+ AH Sbjct: 244 VFSDGVGMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHS 303 Query: 302 VAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ-TKRKHFCGLGSVKTNIGHLDSAAG 360 A VDP I Y+E HGT T LGD IEV+AL AFQ +K FC +GSVK+N+GHLD+AAG Sbjct: 304 FAEVDPSTISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAG 363 Query: 361 IAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWEN-GSGPRRAGVSSF 419 + GLIK VL++ +K L PTL+ PN + DSPFY+ + W++ RAGVS+F Sbjct: 364 VTGLIKTVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDKDLLRAGVSAF 423 Query: 420 GVGGTNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 G GGTN HIVLEEAP +S + +++L+V SA+++EAL + VQ ++ N A Sbjct: 424 GYGGTNVHIVLEEAPKVKS-SASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELA 482 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKPVYFWFAGMALE 539 D+AYTLQ GR F YR+ V C+ + + L+ D + +L V +E Sbjct: 483 DVAYTLQTGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKTQENPDLVFVLPSEYSSIIE 542 Query: 540 EAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSDVYIGQTPVFLFQL-ALA 598 + Y P + E + A G E G+D + + F L ++ Sbjct: 543 NVKELYQK---EPLFLKVFERNMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSII 599 Query: 599 KWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEAL-MLMEKRDRLLEEWRGSEGDLFLL 657 L+ V+P+ ++GTG ++ E+ L L+E L EW E Sbjct: 600 DVLIECDVRPSNIIGTGLAGMISDIYNKSLKPEDVLNQLVENYTELQTEWTHGE------ 653 Query: 658 EALQSEFYEAFDSVTLSAPAIPLLSADAGSNTVLDVTLPDYWVNALGADDDGKSLPAKAE 717 + LL+ V DV P+Y Sbjct: 654 -------------------KVELLTQ------VKDVD-PNY------------------- 668 Query: 718 EADKHLVLHFGAAGEPSGPSGYISLVKSGPELLETVGCIWANGYPLQWDELAKHQNRARV 777 +++H G + I L E+L G W G + W +L + + R R+ Sbjct: 669 -----VIVHIGELLNSEINNNQIILQNDLLEVL---GQAWELGVEINWSKLYEEEYRLRI 720 Query: 778 ILPTYPFTRKRYWVDTQQIKQFQNIWKRQEPQPGKE-NKEEWMYVPSWIRSEYMPEEREQ 836 LPTYPF +KRYW+D + QNI +E K N EW Y P W+ E + + Sbjct: 721 ALPTYPFEKKRYWIDPAEQ---QNITNSEETSIKKRSNIAEWFYTPGWMEKEIVDVIKGS 777 Query: 837 QQGLIAVFATQEPFVARCIERLEQMGHTIARIEAGESFQQNNLS-FEINPEXXXXXXXXX 895 + + +F E E+LE+ GH + + G S+++ +L+ F I P Sbjct: 778 TKSWL-LFLDNEHIGLALKEKLERDGHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLF 836 Query: 896 XXXXXXGDGPVRIVHFWCMHPQSAAREQLPEAEECNRLGYYTLLNIARAVSQLQLQQPVT 955 P IVH W + + E L G+Y+L+++A+ +S+ L P+ Sbjct: 837 NELQKQECLPEEIVHLWNVDNKDLGIETLD-------TGFYSLISLAKTISKFNLLYPIN 889 Query: 956 IDIVANQVAEVTGNETVVPAKATLFGPLRVIPKEYENIACRLIDTDQYDHH--ILCRILS 1013 I+++ N + +V G+E+++ K+TL P++V P+EY NI CR +D D+ ++ + S Sbjct: 890 INVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSDNEEALISNLYS 949 Query: 1014 GPENNRRADWIALRNNY----IWEP----AFKQVRLTTPLHAVHK--RLTSXXXXXXXXX 1063 + + IA+RNN I+EP ++ + + K + S Sbjct: 950 EIQTDIIDTVIAIRNNTRYIRIYEPIPDEKVSEMLVIKENESASKIPNIRSEGVYLITGG 1009 Query: 1064 XXXXXXHVAKYLAEQYQAQVVLLNRSQFLPEAEWDKWYAIHSGDDPVSQKIASLREIKAA 1123 +A+YLA +A+++L++R+ EWD+ ++ + Q+I ++++++ Sbjct: 1010 MGGVGLKLAEYLARTVKAKLILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESL 1069 Query: 1124 ASGFYLVQADITDAAQVRAVFGQILERCGAINGIIQAAGV----PDGAVIQRRSREMCEA 1179 + AD+ D Q+R V Q G ING+I AAGV +++ SR CE Sbjct: 1070 GAKVMTAVADVADEEQMRNVIHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEE 1129 Query: 1180 VFGTKIYGTQVLQKVIGELSRPVDXXXXXXXXXXXXAPPAQVAYSAANSFLDAFAQ--IN 1237 F K++G VL K++ +D VAYSAAN +LD+F+ N Sbjct: 1130 QFLPKVHGVLVLDKLLSNYD--LDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSN 1187 Query: 1238 TKRGYFTQAINWDRWENTG 1256 T +T +INW W+ TG Sbjct: 1188 TSNNRWT-SINWGDWQYTG 1205 Score = 705 bits (1820), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/1361 (32%), Positives = 686/1361 (50%), Gaps = 125/1361 (9%) Query: 5 TRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGV-PAEVYTKENF 63 T+ ++AIIG+ G FPGA+N+ +F+ N+K+G +SI FFTDE+L E+GV P EV + N+ Sbjct: 1371 TKEDNDIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSP-NY 1429 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VKAKGYL + FD FF YTP +A MDPQ R+ HE AW ALE AGY IGVY Sbjct: 1430 VKAKGYLEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVY 1489 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 +G P+ +W+ LS + F I+ LNDKD +ST++SYK NLKGPS +FT CSTS Sbjct: 1490 SGASPNLYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTS 1549 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVA+H ACQ ++ G CD+A+AGG+++T P + GY +Q+GM+ SSDG CR FD ++G + Sbjct: 1550 LVAIHNACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLF 1609 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LK L++A++D D I+AVIKGTAINNDG+RK+GY+APSV+GQ EVI+ A A Sbjct: 1610 GDGVGIVVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEA 1669 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQTKRKHFCGLGSVKTNIGHLDSAAGIAG 363 V+P+ I YIE HGT T LGD IE+KAL+ F + K +GSVK N+GHL++A+G+AG Sbjct: 1670 NVEPESISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAG 1729 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 LIK V A+ ++ L P+++F PN + E +PFY+ R+ EW+ + P RAGVSSFG+GG Sbjct: 1730 LIKTVFAMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGG 1789 Query: 424 TNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAY 483 TNAHI+LEEAP ++ + Q+L+ SAK+++AL++ +++NP AD +Y Sbjct: 1790 TNAHIILEEAPKLEATSNSRPY-QMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSY 1848 Query: 484 TLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFWFAGMALEEAV 542 TLQ GR+ F +R+ + C + G L + + + +V+ K+E V F F+G + Sbjct: 1849 TLQIGRKEFKHRRALVCSSTQEGIELLNQPEGRRVQYVNVKEEHPKVNFLFSGNGSQYVN 1908 Query: 543 QHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGS-----------DVYIGQTPVF 591 RE M+E + V E+L + + Q +F Sbjct: 1909 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILF 1968 Query: 592 LFQLALAKWL--------------------------------LRVGVKPAALMG------ 613 F+ A+AK L L++ VK LM Sbjct: 1969 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2028 Query: 614 ------------------------TGTGAYVAGCLAGVFTLEEALMLME---KRDRLLEE 646 T + A V G V EEA++ E K+ RL+ Sbjct: 2029 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2088 Query: 647 WRGSEGDLFL--LEALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNAL 703 EG L+++ E+ ++TL P IP LS G+ + T P YWV + Sbjct: 2089 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2148 Query: 704 GADDDGKSLPAKAEEADKHLVLHFGAAGEPSGPSGYISLVKSGPE--------------- 748 + + L + G + S + + ++G E Sbjct: 2149 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2208 Query: 749 ---LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKR 805 L + +W G + W++ K + R R+ LP Y F + Y + Q + + Sbjct: 2209 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSK 2268 Query: 806 QEPQPGKENKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTI 865 Q N EW Y P W S + + I VF QE ++ L G + Sbjct: 2269 QSKISKNNNISEWFYTPQWKSSTLFEPNHDVNETWI-VFVDQEGLGNELVKDLLNKGQRV 2327 Query: 866 ARIEAGESF-QQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQL 924 +E G +F ++NN F INPE P RI+H W + + R+ Sbjct: 2328 VTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI--TNEERQAS 2385 Query: 925 PEAEECNR-LGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 E C + LG+Y++ + +A+ + ++I I+ N V +V G+E ++P K+T+ G Sbjct: 2386 IEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTS 2445 Query: 984 RVIPKEYENIACRLID-----TDQYDHHILCRILSGPENNRRADWIALRNNYIWEPAFKQ 1038 V+P+EY ++C +D ++ ++ +++ +N IA R N + ++ Sbjct: 2446 LVVPQEYSYLSCSSVDVVLPLNKEWKSRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEP 2505 Query: 1039 VRLTTPLHAVHKR-LTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLPEAEW 1097 ++L P A K L +AK+LA+ QA +VLL R+ EW Sbjct: 2506 LQLEQP--AKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEW 2563 Query: 1098 DKWYAIHSGDDPV-SQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGAING 1156 D +H ++ + S +I + EI+ S Y++ AD+TD +Q+ + ++ G ING Sbjct: 2564 D----MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2619 Query: 1157 IIQAAGVPDGA---VIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXXXXXX 1213 +I AG+ G +IQ +E CE F KIYG L++ + ++ +D Sbjct: 2620 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLR--NKDLDFCVLMSSISA 2677 Query: 1214 XXAPPAQVAYSAANSFLDAFAQ-INTKRGYFTQAINWDRWE 1253 V+Y+A+N ++D FAQ IN ++NW W+ Sbjct: 2678 VLGGLGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWK 2718 Score = 381 bits (978), Expect = e-103, Method: Compositional matrix adjust. Identities = 200/606 (33%), Positives = 343/606 (56%), Gaps = 13/606 (2%) Query: 1586 ALTPEEGLMILDAALSTAYPQVIV-STVDLPARVEAYRNEKVNLYQDNGGSSAADKVQAS 1644 ++TPEEG+ + ALS +V++ S +L AR++ + +N + D + S Sbjct: 2737 SMTPEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWV--LLNSFNDEKEEELDSTLYHS 2794 Query: 1645 GVNMSAE------ELEHVIRSIWQSVLGHEQISREDDFFDLGGDSLKVLTVAERIYQAVN 1698 + E E+E + IW+++ ++ DD +LGGDSLK +T+ +I++ N Sbjct: 2795 RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFN 2854 Query: 1699 IKIPVSVFFHTTVLNELARHIQAASHTTNEYAAIQKAAPGAYYPLSSAQKRLYFQQQLQP 1758 +++P+ F + + +LA +I A + E+ I A P +YY LSSAQKR Y +L P Sbjct: 2855 VEVPIKELFTLSNIEKLANYISRADKS--EFDVIVPAEPKSYYQLSSAQKRFYVLHRLYP 2912 Query: 1759 DSVAYNILEITSVEGNLDPGKLQNAFDLLIQRHAVLRTSFDVINGEIVQIIHDRAEFQVE 1818 +S AYN + + G L+ +L+ AF LI+RH + RT+ ++ N + VQIIHD A+F + Sbjct: 2913 ESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHIT 2972 Query: 1819 HVTVKXXXXXXXXXXFMQPFDLRSAPLLRVKIVRCGMQKYVWLFDIHHIIADNLSVEILK 1878 + F++PF+ +AP RV ++R QK++ + D+HHI+ D +S +I Sbjct: 2973 QIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFV 3032 Query: 1879 SELISIYNGQADQLKPILLEYVDFVGWQNEQIRRGKFDKQTEYWLQQLSGELPESRLPAD 1938 +L ++Y+G+ +L + ++Y D+ WQ + + K +YWL++ +P +P D Sbjct: 3033 RDLFALYSGE--KLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLEEFKDGVPVLNMPTD 3090 Query: 1939 YPRPAVLSHQGDIYTFTLDETVTGRLKQGMKRNTTTLFMNMMALFSVLLQKYTGQDEVMI 1998 Y RP +L +G +FT+D VT ++K+ + + TTL+ M++++++LL KYTGQ++V+I Sbjct: 3091 YTRPEILDLKGSKISFTIDSNVTKKIKRLLAKEETTLYTLMLSVYNILLGKYTGQEDVVI 3150 Query: 1999 GASLAGRNHADLADMVGMFANVLPFRSRINRDGSFEQLLTEVKTQSLQIFENQDVQFEVL 2058 G+ + GR HADL D++G+F N+L R+ + F Q L EVK Q LQ FE+Q Q+E L Sbjct: 3151 GSPITGRPHADLQDIIGVFVNMLGIRNYPRAEQRFTQFLFEVKEQVLQAFEHQKCQYEDL 3210 Query: 2059 VEALGRSHQLSENPLFNVMLVLPDVAPAEAAMDQVRLQAYPFCNPSSKFDLTLWVYDYDD 2118 V LG + NPLF+V V+ ++ +D + L+ Y ++ DL L V + +D Sbjct: 3211 VNQLGLQGTYNRNPLFDVSFVMQNMDADHMFIDGLELRTYDHDFKRAQMDLLLRVVELED 3270 Query: 2119 SIEMRMEYSTDLFARKTIITMCRHLLDIASLVAGNPDILIKEIMLDSGLVRTEALDLLDD 2178 +IE+ MEY+T L+ R T+ +C ++I + +P+IL+K+I + + + + D Sbjct: 3271 TIELTMEYATSLYTRDTVQKLCERYVEIFEQIVDHPEILLKDISFKQEIQELQPVKVSVD 3330 Query: 2179 GNDFAF 2184 DF F Sbjct: 3331 FGDFNF 3336 >C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I Length = 3339 Score = 706 bits (1822), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/1361 (32%), Positives = 687/1361 (50%), Gaps = 125/1361 (9%) Query: 5 TRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGV-PAEVYTKENF 63 T+ ++AIIG+ G FPGA+N+ +F+ N+K+G +SI FFTDE+L E+GV P EV + N+ Sbjct: 1374 TKEDNDIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSP-NY 1432 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VKAKGYL + FD FF YTP +A MDPQ R+ HE AW ALE AGY IGVY Sbjct: 1433 VKAKGYLEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVY 1492 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 +G P+ +W+ LS + F I+ LNDKD +ST++SYK NLKGPS +FT CSTS Sbjct: 1493 SGASPNLYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTS 1552 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVA+H ACQ ++ G CD+A+AGG+++T P + GY +Q+GM+ SSDG CR FD ++G + Sbjct: 1553 LVAIHNACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLF 1612 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LK L++A++D D I+AVIKGTAINNDG+RK+GY+APSV+GQ EVI+ A A Sbjct: 1613 GDGVGIVVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEA 1672 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQTKRKHFCGLGSVKTNIGHLDSAAGIAG 363 V+P+ I YIE HGT T LGD IE+KAL+ F + K +GSVK N+GHL++A+G+AG Sbjct: 1673 NVEPESISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAG 1732 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 LIK V A+ ++ L P+++F PN + E +PFY+ R+ EW+ + P RAGVSSFG+GG Sbjct: 1733 LIKTVFAMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGG 1792 Query: 424 TNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAY 483 TNAHI+LEEAP ++ + Q+L+ SAK+++AL++ +++NP AD +Y Sbjct: 1793 TNAHIILEEAPKLEATSNSRPY-QMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSY 1851 Query: 484 TLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFWFAGMALEEAV 542 TLQ GR+ F +R+ + C + G L + + + +V+ K+E V F F+G + Sbjct: 1852 TLQIGRKEFKHRRALVCSSTQEGIELLNQPEGRRVQYVNVKEEHPKVNFLFSGNGSQYVN 1911 Query: 543 QHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGS-----------DVYIGQTPVF 591 RE M+E + V E+L + + Q +F Sbjct: 1912 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILF 1971 Query: 592 LFQLALAKWL--------------------------------LRVGVKPAALMG------ 613 F+ A+AK L L++ VK LM Sbjct: 1972 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2031 Query: 614 ------------------------TGTGAYVAGCLAGVFTLEEALMLME---KRDRLLEE 646 T + A V G V EEA++ E K+ RL+ Sbjct: 2032 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKKRLMCM 2091 Query: 647 WRGSEGDLFL--LEALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNAL 703 EG L+++ E+ ++TL P IP LS G+ + T P YWV + Sbjct: 2092 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2151 Query: 704 GADDDGKSLPAKAEEADKHLVLHFGAAGEPSGPSGYISLVKSGPE--------------- 748 + + L + G + S + + ++G E Sbjct: 2152 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2211 Query: 749 ---LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKR 805 L + +W G + W++ K + R R+ LP Y F + Y + Q + + Sbjct: 2212 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSK 2271 Query: 806 QEPQPGKENKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTI 865 Q N EW Y P W S + + I VF QE ++ L G + Sbjct: 2272 QSKISKNNNISEWFYTPQWKSSTLFEPNHDVNETWI-VFVDQEGLGNELVKDLLNKGQRV 2330 Query: 866 ARIEAGESF-QQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQL 924 +E G +F ++NN F INPE P RI+H W + + R+ Sbjct: 2331 VTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI--TNEERQAS 2388 Query: 925 PEAEECNR-LGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 E C + LG+Y++ + +A+ + ++I I+ N V +V G+E ++P K+T+ G Sbjct: 2389 IEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTS 2448 Query: 984 RVIPKEYENIACRLID-----TDQYDHHILCRILSGPENNRRADWIALRNNYIWEPAFKQ 1038 V+P+EY ++C +D ++ + ++ +++ +N IA R N + ++ Sbjct: 2449 LVVPQEYSYLSCSSVDVVLPLNKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEP 2508 Query: 1039 VRLTTPLHAVHKR-LTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLPEAEW 1097 ++L P A K L +AK+LA+ QA +VLL R+ EW Sbjct: 2509 LQLEQP--AKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTLQANLVLLTRTGLPNRDEW 2566 Query: 1098 DKWYAIHSGDDPV-SQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGAING 1156 D +H ++ + S +I + EI+ S Y++ AD+TD +Q+ + ++ G ING Sbjct: 2567 D----MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2622 Query: 1157 IIQAAGVPDGA---VIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXXXXXX 1213 +I AG+ G +IQ +E CE F KIYG L++ + ++ +D Sbjct: 2623 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLR--NKDLDFCVLMSSISA 2680 Query: 1214 XXAPPAQVAYSAANSFLDAFAQ-INTKRGYFTQAINWDRWE 1253 V+Y+A+N ++D FAQ IN ++NW W+ Sbjct: 2681 VLGGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWK 2721 Score = 562 bits (1448), Expect = e-157, Method: Compositional matrix adjust. Identities = 300/654 (45%), Positives = 404/654 (61%), Gaps = 8/654 (1%) Query: 2 KENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKE 61 +++++TGLE+AIIGM+G FPGA + QF+ N+KNGVDSIS FT+++L + GV EV Sbjct: 6 QDDSKTGLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLEVLQHP 65 Query: 62 NFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIG 121 NFVKAKGYL E EYFD SFF YTP EA+ MDPQ R+L E W ALE AGY P + IG Sbjct: 66 NFVKAKGYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIG 125 Query: 122 VYAGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACS 181 +Y G +F+W + + S + E E L+ KD +ST SYKL LKGPS+TL+TACS Sbjct: 126 LYVGASTNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACS 185 Query: 182 TSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGT 241 TSL+++H AC+ +++GEC +A AGGVS+T P +NGY + +GM S DG+ R FDA + G Sbjct: 186 TSLLSIHLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGA 245 Query: 242 VVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHR 301 V +G+G+VILKRLEDA+ D D IY VIKG+A NNDG RKVGY+APSV+GQAEVI+ AH Sbjct: 246 VFSDGVGMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHS 305 Query: 302 VAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ-TKRKHFCGLGSVKTNIGHLDSAAG 360 A VDP I YIE HGT T LGD IEV+AL AFQ +K FC +GSVK+N+GHLD+AAG Sbjct: 306 FAEVDPSTISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAG 365 Query: 361 IAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGP-RRAGVSSF 419 + GLIK VL++ +K L PTL+ PN + DSPFY+ + W++ RAGVS+F Sbjct: 366 VTGLIKTVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAF 425 Query: 420 GVGGTNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 G GGTN HIVLEEAP +S + +++L+V SA+++EAL + V+ ++ N A Sbjct: 426 GYGGTNVHIVLEEAPKVKS-SASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELA 484 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKPVYFWFAGMALE 539 D+AYTLQ GR F YR+ V C+ + + L+ D + +L V +E Sbjct: 485 DVAYTLQTGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKTQENPDLVFVLPSEYSSIIE 544 Query: 540 EAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSDVYIGQTPVFLFQL-ALA 598 + Y P + E + A G E G+D + + F L ++ Sbjct: 545 NVKELYQK---EPLFLQVFERNMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSII 601 Query: 599 KWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALM-LMEKRDRLLEEWRGSE 651 L+ V+P+ ++GTG V+ E+ L L+E L EW E Sbjct: 602 DVLIECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNPLVENYIELQTEWTHGE 655 Score = 379 bits (974), Expect = e-102, Method: Compositional matrix adjust. Identities = 200/606 (33%), Positives = 342/606 (56%), Gaps = 13/606 (2%) Query: 1586 ALTPEEGLMILDAALSTAYPQVIV-STVDLPARVEAYRNEKVNLYQDNGGSSAADKVQAS 1644 ++TPEEG+ + ALS +V++ S +L AR++ + +N + D + S Sbjct: 2740 SMTPEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWV--LLNSFNDEKEEELDSTLYHS 2797 Query: 1645 GVNMSAE------ELEHVIRSIWQSVLGHEQISREDDFFDLGGDSLKVLTVAERIYQAVN 1698 + E E+E + IW+++ ++ DD +LGGDSLK +T+ +I++ N Sbjct: 2798 RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFN 2857 Query: 1699 IKIPVSVFFHTTVLNELARHIQAASHTTNEYAAIQKAAPGAYYPLSSAQKRLYFQQQLQP 1758 +++P+ F + + +LA +I A + E+ I A P ++Y LSSAQKR Y +L P Sbjct: 2858 VEVPIKELFTLSNIEKLANYISRADKS--EFDVIVPAEPKSHYQLSSAQKRFYVLHRLYP 2915 Query: 1759 DSVAYNILEITSVEGNLDPGKLQNAFDLLIQRHAVLRTSFDVINGEIVQIIHDRAEFQVE 1818 +S AYN + + G L+ +L+ AF LI+RH + RT+ ++ N + VQIIHD A+F + Sbjct: 2916 ESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHIT 2975 Query: 1819 HVTVKXXXXXXXXXXFMQPFDLRSAPLLRVKIVRCGMQKYVWLFDIHHIIADNLSVEILK 1878 + F++PF+ +AP RV ++R QK++ + D+HHI+ D +S +I Sbjct: 2976 QIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFV 3035 Query: 1879 SELISIYNGQADQLKPILLEYVDFVGWQNEQIRRGKFDKQTEYWLQQLSGELPESRLPAD 1938 +L ++Y+G+ +L + ++Y D+ WQ + + K +YWL Q +P +P D Sbjct: 3036 RDLFALYSGE--KLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLDQFKDGVPVLNMPTD 3093 Query: 1939 YPRPAVLSHQGDIYTFTLDETVTGRLKQGMKRNTTTLFMNMMALFSVLLQKYTGQDEVMI 1998 Y RP +L +G +FT+D VT ++K+ + + TTL+ M++++++LL KYTGQ++V+I Sbjct: 3094 YTRPEILDLKGSKISFTIDSNVTKKIKRLLAKEETTLYTLMLSVYNILLGKYTGQEDVVI 3153 Query: 1999 GASLAGRNHADLADMVGMFANVLPFRSRINRDGSFEQLLTEVKTQSLQIFENQDVQFEVL 2058 G+ + GR HADL D++G+F N+L R+ + F Q L EVK Q LQ FE+Q Q+E L Sbjct: 3154 GSPITGRPHADLQDIIGVFVNMLGIRNYPRAEQRFTQFLFEVKEQVLQAFEHQKCQYEDL 3213 Query: 2059 VEALGRSHQLSENPLFNVMLVLPDVAPAEAAMDQVRLQAYPFCNPSSKFDLTLWVYDYDD 2118 V LG + NPLF+V V+ ++ +D + L+ Y ++ DL L V + +D Sbjct: 3214 VNQLGLQGTYNRNPLFDVSFVMQNMDADHMFIDGLELRTYDHDFKRAQMDLLLRVVELED 3273 Query: 2119 SIEMRMEYSTDLFARKTIITMCRHLLDIASLVAGNPDILIKEIMLDSGLVRTEALDLLDD 2178 +IE+ MEY+T L+ R T+ +C ++I + +P+IL+K+I + + + + D Sbjct: 3274 TIELTMEYATSLYTRDTVQKLCERYVEIFEQIVDHPEILLKDISFKQEIQELQPVKVSVD 3333 Query: 2179 GNDFAF 2184 DF F Sbjct: 3334 FGDFNF 3339 Score = 207 bits (527), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 146/530 (27%), Positives = 250/530 (47%), Gaps = 35/530 (6%) Query: 748 ELLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQE 807 +LLE +G W G + W +L + + R R+ LPTYPF +KRYW+D + QNI +E Sbjct: 693 DLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQ---QNITNSEE 749 Query: 808 PQPGKE--NKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTI 865 K+ N +W Y P W+ E + + + + +F E E+LE+ GH + Sbjct: 750 ETSIKKRSNIAKWFYTPGWMEKEIVDVTKGSTKSWL-LFLDNEHIGLALKEKLERDGHRV 808 Query: 866 ARIEAGESFQQNNLS-FEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQL 924 + G S+++ +L+ F I P P IVH W + + E L Sbjct: 809 ITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNKDLGIETL 868 Query: 925 PEAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPLR 984 G+Y+L+++A+ +S+ L P+ I+++ N + +V G+E+++ K+TL P++ Sbjct: 869 D-------TGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIK 921 Query: 985 VIPKEYENIACRLIDTDQYDHH--ILCRILSGPENNRRADWIALRNNY----IWEP---- 1034 V P+EY NI CR +D D+ ++ + S + + IA+RNN I+EP Sbjct: 922 VFPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDE 981 Query: 1035 AFKQVRLTTPLHAVHK--RLTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFL 1092 ++ + + K + S +A+YLA +A+++L++R+ Sbjct: 982 KVSEMLVINENESASKIPNIRSEGVYLITGGIGGVGLKLAEYLARTVKAKLILVSRTALP 1041 Query: 1093 PEAEWDKWYAIHSGDDPVSQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCG 1152 EWD+ ++ + Q+I ++++++ + AD+ D Q+R V Q G Sbjct: 1042 DREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFG 1101 Query: 1153 AINGIIQAAGV----PDGAVIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXX 1208 ING+I AAGV +++ SR CE F K++G VL K++ +D Sbjct: 1102 HINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYD--LDFCYLV 1159 Query: 1209 XXXXXXXAPPAQVAYSAANSFLDAFAQ--INTKRGYFTQAINWDRWENTG 1256 VAYSAAN +LD+F+ NT + +INW W+ TG Sbjct: 1160 SSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWI-SINWGDWQYTG 1208 >C2P7V8.1 C2P7V8_BACCE Polyketide synthase type I Length = 3338 Score = 701 bits (1809), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/1361 (32%), Positives = 686/1361 (50%), Gaps = 125/1361 (9%) Query: 5 TRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGV-PAEVYTKENF 63 T+ ++AIIG+ G FPGA+N+ +F+ N+K+G +SI FFTDE+L E+GV P EV + N+ Sbjct: 1373 TKEDNDIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVNSP-NY 1431 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VKAKGYL + FD FF YTP +A MDPQ R+ HE AW ALE AGY IGVY Sbjct: 1432 VKAKGYLEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVY 1491 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 +G P+ +W+ LS + F I+ LNDKD +ST++SYK NLKGPS +FT CSTS Sbjct: 1492 SGASPNLYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTS 1551 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVA+H ACQ ++ G CD+A+AGG+++T P + GY +Q+GM+ SSDG CR FD ++G + Sbjct: 1552 LVAIHNACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLF 1611 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LK L++A++D D I+AVIKGTAINNDG+RK+GY+APSV+GQ EVI+ A A Sbjct: 1612 GDGVGIVVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEA 1671 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQTKRKHFCGLGSVKTNIGHLDSAAGIAG 363 V+P+ I YIE HGT T LGD IE+KAL+ F + K +GSVK N+GHL++A+G+AG Sbjct: 1672 NVEPESISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAG 1731 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 LIK V A+ ++ L P+++F PN + E +PFY+ ++ EW+ + P RAGVSSFG+GG Sbjct: 1732 LIKTVFAMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGG 1791 Query: 424 TNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAY 483 TNAHI+LEEAP ++ + Q+L+ SAK+++AL++ +++NP AD +Y Sbjct: 1792 TNAHIILEEAPKLEATSNSRPY-QMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASY 1850 Query: 484 TLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFWFAGMALEEAV 542 TLQ GR+ F +R+ + C + G L + + + + K+E ++F F+G + Sbjct: 1851 TLQIGRKEFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVN 1910 Query: 543 QHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGS-----------DVYIGQTPVF 591 RE M+E + V E+L + + Q +F Sbjct: 1911 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILF 1970 Query: 592 LFQLALAKWL--------------------------------LRVGVKPAALMG------ 613 F+ A+AK L L++ VK LM Sbjct: 1971 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2030 Query: 614 ------------------------TGTGAYVAGCLAGVFTLEEALMLME---KRDRLLEE 646 T + A V G V EEA++ E K+ RL+ Sbjct: 2031 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2090 Query: 647 WRGSEGDLFL--LEALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNAL 703 EG L+++ E+ ++TL P IP LS G+ + T P YWV + Sbjct: 2091 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2150 Query: 704 GADDDGKSLPAKAEEADKHLVLHFGAAGEPSGPSGYISLVKSGPE--------------- 748 + + L + G + S + + ++G E Sbjct: 2151 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2210 Query: 749 ---LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKR 805 L + +W G + W++ K + R R+ LP Y F + Y + Q + + Sbjct: 2211 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSK 2270 Query: 806 QEPQPGKENKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTI 865 Q N EW Y P W S + + I VF QE ++ L G + Sbjct: 2271 QSKISKNNNISEWFYTPQWKSSTLFEPNHDVNETWI-VFVDQEGLGNELVKDLLNKGQRV 2329 Query: 866 ARIEAGESF-QQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQL 924 +E G +F ++NN F INPE P RI+H W + + R+ Sbjct: 2330 VTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI--TNEERQAS 2387 Query: 925 PEAEECNR-LGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 E C + LG+Y++ + +A+ + ++I I+ N V +V G+E ++P K+T+ G Sbjct: 2388 IEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTS 2447 Query: 984 RVIPKEYENIACRLID-----TDQYDHHILCRILSGPENNRRADWIALRNNYIWEPAFKQ 1038 V+P+EY ++C +D ++ + ++ +++ +N IA R N + ++ Sbjct: 2448 LVVPQEYSYLSCSSVDVVLPLNKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEP 2507 Query: 1039 VRLTTPLHAVHKR-LTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLPEAEW 1097 ++L P A K L +AK+LA+ QA +VLL R+ EW Sbjct: 2508 LQLEQP--AKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEW 2565 Query: 1098 DKWYAIHSGDDPV-SQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGAING 1156 D +H ++ + S +I + EI+ S Y++ AD+TD +Q+ + ++ G ING Sbjct: 2566 D----MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2621 Query: 1157 IIQAAGVPDGA---VIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXXXXXX 1213 +I AG+ G +IQ +E CE F KIYG L++ + ++ +D Sbjct: 2622 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLINLEECLR--NKDLDFCVLMSSISA 2679 Query: 1214 XXAPPAQVAYSAANSFLDAFAQ-INTKRGYFTQAINWDRWE 1253 V+Y+A+N ++D FAQ IN ++NW W+ Sbjct: 2680 VLGGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWK 2720 Score = 563 bits (1452), Expect = e-158, Method: Compositional matrix adjust. Identities = 301/654 (46%), Positives = 405/654 (61%), Gaps = 8/654 (1%) Query: 2 KENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKE 61 +++++TGLE+AIIGM+G FPGA + QF+ N+KNGVDSIS FT+++L + GV +V Sbjct: 6 QDDSKTGLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHP 65 Query: 62 NFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIG 121 NFVKAKGYL E EYFD SFF YTP EA+ MDPQ R+L E W ALE AGY P + IG Sbjct: 66 NFVKAKGYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIG 125 Query: 122 VYAGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACS 181 +Y G +F+W + + S + E E L+ KD +ST SYKL LKGPS+TL+TACS Sbjct: 126 LYVGASTNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACS 185 Query: 182 TSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGT 241 TSL+++H AC+ +++GEC +A AGGVS+T P +NGY + +GM S DG+ R FDA + G Sbjct: 186 TSLLSIHLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGA 245 Query: 242 VVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHR 301 V +G+G+VILKRLEDA+ D D IY VIKG+A NNDG RKVGY+APSV+GQAEVI+ AH Sbjct: 246 VFSDGVGMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHS 305 Query: 302 VAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ-TKRKHFCGLGSVKTNIGHLDSAAG 360 A VDP I YIE HGT T LGD IEV+AL AFQ +K FC +GSVK+N+GHLD+AAG Sbjct: 306 FAEVDPSTISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAG 365 Query: 361 IAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGP-RRAGVSSF 419 + GLIK VL++ +K L PTL+ PN + DSPFY+ + W++ RAGVS+F Sbjct: 366 VTGLIKTVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAF 425 Query: 420 GVGGTNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 G GGTN HIVLEEAP +S + +++L+V SA+++EAL + VQ ++ N A Sbjct: 426 GYGGTNVHIVLEEAPKVKS-SASTREKKLMVLSARSKEALNNATVNLVQYLESNKDVELA 484 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKPVYFWFAGMALE 539 D+AYTLQ GR F+YR+ V C+ + + L+ D + EL V +E Sbjct: 485 DVAYTLQTGRRPFTYRRAVLCKDIDSAIDNLKTVKDFHVKTQENPELVFVLPSEYSSIIE 544 Query: 540 EAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSDVYIGQTPVFLFQL-ALA 598 + Y P + E + A G E G+D + + F L ++ Sbjct: 545 NVKELYQK---EPLFLQVFERNMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSII 601 Query: 599 KWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALM-LMEKRDRLLEEWRGSE 651 L+ V+P+ ++GTG V+ E+ L L+E L EW E Sbjct: 602 DVLIECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNPLVENYIELQTEWTHGE 655 Score = 378 bits (970), Expect = e-102, Method: Compositional matrix adjust. Identities = 199/606 (32%), Positives = 342/606 (56%), Gaps = 13/606 (2%) Query: 1586 ALTPEEGLMILDAALSTAYPQVIV-STVDLPARVEAYRNEKVNLYQDNGGSSAADKVQAS 1644 ++TPEEG+ + ALS +V++ S +L AR++ + +N + D + S Sbjct: 2739 SMTPEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWV--LLNSFNDEKEEELDSTLYHS 2796 Query: 1645 GVNMSAE------ELEHVIRSIWQSVLGHEQISREDDFFDLGGDSLKVLTVAERIYQAVN 1698 + E E+E + IW+++ ++ DD +LGGDSLK +T+ +I++ N Sbjct: 2797 RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFN 2856 Query: 1699 IKIPVSVFFHTTVLNELARHIQAASHTTNEYAAIQKAAPGAYYPLSSAQKRLYFQQQLQP 1758 +++P+ F + + +LA +I A + E+ I A P ++Y LSSAQKR Y +L P Sbjct: 2857 VEVPIKELFTLSNIEKLANYISRADKS--EFDVIVPAEPKSHYQLSSAQKRFYVLHRLYP 2914 Query: 1759 DSVAYNILEITSVEGNLDPGKLQNAFDLLIQRHAVLRTSFDVINGEIVQIIHDRAEFQVE 1818 +S AYN + + G L+ +L+ AF LI+RH + RT+ ++ N + VQIIHD A+F + Sbjct: 2915 ESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHIT 2974 Query: 1819 HVTVKXXXXXXXXXXFMQPFDLRSAPLLRVKIVRCGMQKYVWLFDIHHIIADNLSVEILK 1878 + F++PF+ +AP RV ++R QK++ + D+HHI+ D +S +I Sbjct: 2975 QIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFV 3034 Query: 1879 SELISIYNGQADQLKPILLEYVDFVGWQNEQIRRGKFDKQTEYWLQQLSGELPESRLPAD 1938 +L ++Y+G+ +L + ++Y D+ WQ + + K +YWL Q +P +P D Sbjct: 3035 RDLFALYSGE--KLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLDQFKDGVPVLNMPTD 3092 Query: 1939 YPRPAVLSHQGDIYTFTLDETVTGRLKQGMKRNTTTLFMNMMALFSVLLQKYTGQDEVMI 1998 Y RP +L +G +FT+D VT ++K+ + + TTL+ M++++++LL KYTGQ++V+I Sbjct: 3093 YTRPEILDLKGSKISFTIDSNVTKKIKRLLAKEETTLYTLMLSVYNILLGKYTGQEDVVI 3152 Query: 1999 GASLAGRNHADLADMVGMFANVLPFRSRINRDGSFEQLLTEVKTQSLQIFENQDVQFEVL 2058 G+ + GR HADL D++G+F N+L R+ + F Q L EVK Q LQ FE+Q Q+E L Sbjct: 3153 GSPITGRPHADLQDIIGVFVNMLGIRNYPRAEQRFTQFLFEVKEQVLQAFEHQKCQYEDL 3212 Query: 2059 VEALGRSHQLSENPLFNVMLVLPDVAPAEAAMDQVRLQAYPFCNPSSKFDLTLWVYDYDD 2118 V LG + NPLF+V V+ ++ +D + L+ Y ++ DL L V + +D Sbjct: 3213 VNQLGLQGTYNRNPLFDVSFVMQNMDADHMFIDGLELRTYDHDFKRAQMDLLLRVVELED 3272 Query: 2119 SIEMRMEYSTDLFARKTIITMCRHLLDIASLVAGNPDILIKEIMLDSGLVRTEALDLLDD 2178 +IE+ MEY+T L+ + T+ +C ++I + +P+IL+K+I + + + + D Sbjct: 3273 TIELTMEYATSLYTKDTVQKLCERYVEIFEQIVDHPEILLKDISFKQEIQELQPVKVSVD 3332 Query: 2179 GNDFAF 2184 DF F Sbjct: 3333 FGDFNF 3338 Score = 209 bits (533), Expect = 2e-51, Method: Compositional matrix adjust. Identities = 148/529 (27%), Positives = 250/529 (47%), Gaps = 34/529 (6%) Query: 748 ELLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQE 807 +LLE +G W G + W +L + + R R+ LPTYPF +KRYW+D + QNI +E Sbjct: 693 DLLELLGQAWELGVEINWSKLYEEEFRLRIALPTYPFEKKRYWIDPAEQ---QNIINSEE 749 Query: 808 PQPGKE-NKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTIA 866 K N EW Y P W+ E + + + + +F E E+LE+ GH + Sbjct: 750 TSIKKRSNIAEWFYTPGWMEKEIVDVTKGSTKSWL-LFLDNEHIGLALKEKLERDGHRVI 808 Query: 867 RIEAGESFQQNNLS-FEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQLP 925 + G S+++ +L+ F I P P IVH W + + E L Sbjct: 809 TVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNKDLGIETLD 868 Query: 926 EAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPLRV 985 G+Y+L+++A+ +S+ L P+ I+++ N + +V G+E+++ K+TL P++V Sbjct: 869 -------TGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKV 921 Query: 986 IPKEYENIACRLIDTDQYDHH--ILCRILSGPENNRRADWIALRNNY----IWEP----A 1035 P+EY NI CR +D D+ ++ + S + + IA+RNN I+EP Sbjct: 922 FPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQADIIDTVIAIRNNTRYIRIYEPIPDEK 981 Query: 1036 FKQVRLTTPLHAVHK--RLTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLP 1093 ++ + + K + S +A+YLA +A+++L++R+ Sbjct: 982 VSEMLVINENESASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPD 1041 Query: 1094 EAEWDKWYAIHSGDDPVSQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGA 1153 EWD+ ++ + Q+I ++++++ + AD+ D Q+R V Q G Sbjct: 1042 REEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFGH 1101 Query: 1154 INGIIQAAGV----PDGAVIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXX 1209 ING+I AAGV +++ SR CE F K++G VL K++ +D Sbjct: 1102 INGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYD--LDFCYLVS 1159 Query: 1210 XXXXXXAPPAQVAYSAANSFLDAFAQ--INTKRGYFTQAINWDRWENTG 1256 VAYSAAN +LD+F+ NT +T +INW W+ TG Sbjct: 1160 SLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT-SINWGDWQYTG 1207 >C0JRE5.1 C0JRE5_BACCE ZmaA Length = 3336 Score = 701 bits (1808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/1361 (32%), Positives = 685/1361 (50%), Gaps = 125/1361 (9%) Query: 5 TRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGV-PAEVYTKENF 63 T+ ++AIIG+ G FPGA+N+ +F+ N+K+G +SI FFTDE+L E+GV P EV + N+ Sbjct: 1371 TKEDNDIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSP-NY 1429 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VKAKGYL + FD FF YTP +A MDPQ R+ HE AW ALE AGY IGVY Sbjct: 1430 VKAKGYLEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVY 1489 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 +G P+ +W+ LS + F I+ LNDKD +ST++SYK NLKGPS +FT CSTS Sbjct: 1490 SGASPNLYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTS 1549 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVA+H ACQ ++ G CD+A+AGG+++T P + GY +Q+GM+ SSDG CR FD ++G + Sbjct: 1550 LVAIHNACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLF 1609 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LK L++A++D D I+AVIKGTAINNDG+RK+GY+APSV+GQ EVI+ A A Sbjct: 1610 GDGVGIVVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEA 1669 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQTKRKHFCGLGSVKTNIGHLDSAAGIAG 363 V+P+ I YIE HGT T LGD IE+KAL+ F + K +GSVK N+GHL++A+G+AG Sbjct: 1670 NVEPESISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAG 1729 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 LIK V A+ ++ L P+++F PN + E +PFY+ ++ EW+ + P RAGVSSFG+GG Sbjct: 1730 LIKTVFAMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGG 1789 Query: 424 TNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAY 483 TNAHI+LEEAP ++ + Q+L+ SAK+++AL++ +++NP AD +Y Sbjct: 1790 TNAHIILEEAPKLEATSNSRPY-QMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASY 1848 Query: 484 TLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFWFAGMALEEAV 542 TLQ GR+ F +R+ + C + G L + + + + K+E ++F F+G + Sbjct: 1849 TLQIGRKEFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVN 1908 Query: 543 QHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGS-----------DVYIGQTPVF 591 RE M+E V E+L + + Q +F Sbjct: 1909 MGLELYEQEAIFREAMDECFAILQSFTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILF 1968 Query: 592 LFQLALAKWL--------------------------------LRVGVKPAALMG------ 613 F+ A+AK L L++ VK LM Sbjct: 1969 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2028 Query: 614 ------------------------TGTGAYVAGCLAGVFTLEEALMLME---KRDRLLEE 646 T + A V G V EEA++ E K+ RL+ Sbjct: 2029 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2088 Query: 647 WRGSEGDLFL--LEALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNAL 703 EG L+++ E+ ++TL P IP LS G+ + T P YWV + Sbjct: 2089 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2148 Query: 704 GADDDGKSLPAKAEEADKHLVLHFGAAGEPSGPSGYISLVKSGPE--------------- 748 + + L + G + S + + ++G E Sbjct: 2149 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2208 Query: 749 ---LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKR 805 L + +W G + W++ K + R R+ LP Y F + Y + Q + + Sbjct: 2209 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSK 2268 Query: 806 QEPQPGKENKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTI 865 Q N EW Y P W S + + I VF QE ++ L G + Sbjct: 2269 QSKISKNNNISEWFYTPQWKSSTLFEPNHDVNETWI-VFVDQEGLGNELVKDLLNKGQRV 2327 Query: 866 ARIEAGESF-QQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQL 924 +E G +F ++NN F INPE P RI+H W + + R+ Sbjct: 2328 VTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI--TNEERQAS 2385 Query: 925 PEAEECNR-LGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 E C + LG+Y++ + +A+ + ++I I+ N V +V G+E ++P K+T+ G Sbjct: 2386 IEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTS 2445 Query: 984 RVIPKEYENIACRLIDT-----DQYDHHILCRILSGPENNRRADWIALRNNYIWEPAFKQ 1038 V+P+EY ++C +D ++ + ++ +++ +N IA R N + ++ Sbjct: 2446 LVVPQEYSYLSCSSVDVVLPLKKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEP 2505 Query: 1039 VRLTTPLHAVHKR-LTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLPEAEW 1097 ++L P A K L +AK+LA+ QA +VLL R+ EW Sbjct: 2506 LQLEQP--AKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEW 2563 Query: 1098 DKWYAIHSGDDPV-SQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGAING 1156 D +H ++ + S +I + EI+ S Y++ AD+TD +Q+ + ++ G ING Sbjct: 2564 D----MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2619 Query: 1157 IIQAAGVPDGA---VIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXXXXXX 1213 +I AG+ G +IQ +E CE F KIYG L++ + ++ +D Sbjct: 2620 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLR--NKDLDFCVLMSSISA 2677 Query: 1214 XXAPPAQVAYSAANSFLDAFAQ-INTKRGYFTQAINWDRWE 1253 V+Y+A+N ++D FAQ IN ++NW W+ Sbjct: 2678 VLGGLGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWK 2718 Score = 560 bits (1443), Expect = e-157, Method: Compositional matrix adjust. Identities = 299/654 (45%), Positives = 403/654 (61%), Gaps = 8/654 (1%) Query: 2 KENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKE 61 +++++TGLE+AIIGM+G FPGA + QF+ N+KNGVDSIS FT+++L + GV +V Sbjct: 4 QDDSKTGLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHP 63 Query: 62 NFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIG 121 NFVKAKGYL E EYFD SFF YTP EA+ MDPQ R+L E W ALE AGY P + IG Sbjct: 64 NFVKAKGYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIG 123 Query: 122 VYAGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACS 181 +Y G +F+W + + S + E E L+ KD +ST SYKL LKGPS+TL+TACS Sbjct: 124 LYVGASTNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACS 183 Query: 182 TSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGT 241 TSL+++H AC+ +++GEC +A AGGVS+T P +NGY + +GM S DG+ R FDA + G Sbjct: 184 TSLLSIHLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGA 243 Query: 242 VVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHR 301 V +G+G+VILKRLEDA+ D D IY VIKG+A NNDG RKVGY+APSV+GQAEVI+ AH Sbjct: 244 VFSDGVGMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHS 303 Query: 302 VAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ-TKRKHFCGLGSVKTNIGHLDSAAG 360 A VDP I Y+E HGT T LGD IEV+AL AFQ +K FC +GSVK+N+GHLD+AAG Sbjct: 304 FAEVDPSTISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAG 363 Query: 361 IAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGP-RRAGVSSF 419 + GLIK VL++ +K L PTL+ PN + DSPFY+ + W++ RAGVS+F Sbjct: 364 VTGLIKTVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSDDNDLLRAGVSAF 423 Query: 420 GVGGTNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 G GGTN HIVLEEAP +S + +++L+V SA+++EAL + VQ ++ N A Sbjct: 424 GYGGTNVHIVLEEAPKVKS-SASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELA 482 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKPVYFWFAGMALE 539 D+AYTLQ GR F YR+ V C + + L+ D + +L V +E Sbjct: 483 DVAYTLQTGRRPFPYRRAVLCMDIDSAIDNLKTVKDFHVKTQENPDLVFVLPSEYSSIIE 542 Query: 540 EAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSDVYIGQTPVFLFQL-ALA 598 + Y P + E + A G E G+D + + F L ++ Sbjct: 543 NVKELYQK---EPLFLKVFERNMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSII 599 Query: 599 KWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEAL-MLMEKRDRLLEEWRGSE 651 L+ V+P+ ++GTG V+ E+ L L+E L EW E Sbjct: 600 DVLIECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNQLVENYTELQTEWTHGE 653 Score = 379 bits (974), Expect = e-102, Method: Compositional matrix adjust. Identities = 199/606 (32%), Positives = 343/606 (56%), Gaps = 13/606 (2%) Query: 1586 ALTPEEGLMILDAALSTAYPQVIV-STVDLPARVEAYRNEKVNLYQDNGGSSAADKVQAS 1644 ++TPEEG+ + ALS +V++ S +L AR++ + +N + D + S Sbjct: 2737 SMTPEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWV--LLNSFNDEKEEELDSTLYHS 2794 Query: 1645 GVNMSAE------ELEHVIRSIWQSVLGHEQISREDDFFDLGGDSLKVLTVAERIYQAVN 1698 + E E+E + IW+++ ++ DD +LGGDSLK +T+ +I++ N Sbjct: 2795 RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFN 2854 Query: 1699 IKIPVSVFFHTTVLNELARHIQAASHTTNEYAAIQKAAPGAYYPLSSAQKRLYFQQQLQP 1758 +++P+ F + + +LA +I A + E+ I A P ++Y LSSAQKR Y +L P Sbjct: 2855 VEVPIKELFTLSNIEKLANYISRADKS--EFDVIVPAEPKSHYQLSSAQKRFYVLHRLYP 2912 Query: 1759 DSVAYNILEITSVEGNLDPGKLQNAFDLLIQRHAVLRTSFDVINGEIVQIIHDRAEFQVE 1818 +S AYN + + G L+ +L+ AF LI+RH + RT+ ++ N + VQIIHD A+F + Sbjct: 2913 ESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHIT 2972 Query: 1819 HVTVKXXXXXXXXXXFMQPFDLRSAPLLRVKIVRCGMQKYVWLFDIHHIIADNLSVEILK 1878 + F++PF+ +AP RV ++R QK++ + D+HHI+ D +S +I Sbjct: 2973 QIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFV 3032 Query: 1879 SELISIYNGQADQLKPILLEYVDFVGWQNEQIRRGKFDKQTEYWLQQLSGELPESRLPAD 1938 +L ++Y+G+ +L + ++Y D+ WQ + + K +YWL+Q +P +P D Sbjct: 3033 RDLFALYSGE--KLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLEQFKDGVPVLNMPTD 3090 Query: 1939 YPRPAVLSHQGDIYTFTLDETVTGRLKQGMKRNTTTLFMNMMALFSVLLQKYTGQDEVMI 1998 Y RP ++ +G +FT+D VT ++K+ + + TTL+ M++++++LL KYTGQ++V+I Sbjct: 3091 YTRPEIIDLKGSKISFTIDSNVTKKIKRLLAKEETTLYTLMLSVYNILLGKYTGQEDVVI 3150 Query: 1999 GASLAGRNHADLADMVGMFANVLPFRSRINRDGSFEQLLTEVKTQSLQIFENQDVQFEVL 2058 G+ + GR HADL D++G+F N+L R+ + F Q L EVK Q LQ FE+Q Q+E L Sbjct: 3151 GSPITGRPHADLQDIIGVFVNMLGIRNYPRAEQRFTQFLFEVKEQVLQAFEHQKCQYEDL 3210 Query: 2059 VEALGRSHQLSENPLFNVMLVLPDVAPAEAAMDQVRLQAYPFCNPSSKFDLTLWVYDYDD 2118 V LG + NPLF+V V+ ++ +D + L+ Y ++ DL L V + +D Sbjct: 3211 VNKLGLQGTYNRNPLFDVSFVMQNMDADHMFIDGLELRTYDHDFKRAQMDLLLRVVELED 3270 Query: 2119 SIEMRMEYSTDLFARKTIITMCRHLLDIASLVAGNPDILIKEIMLDSGLVRTEALDLLDD 2178 +IE+ MEY+T L+ R T+ +C ++I + +P+IL+K+I + + + + D Sbjct: 3271 TIELTMEYATSLYTRDTVQKLCERYVEIFEQIVDHPEILLKDISFKQEIQELQPVKVSVD 3330 Query: 2179 GNDFAF 2184 DF F Sbjct: 3331 FGDFNF 3336 Score = 213 bits (541), Expect = 2e-52, Method: Compositional matrix adjust. Identities = 149/529 (28%), Positives = 250/529 (47%), Gaps = 34/529 (6%) Query: 748 ELLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQE 807 +LLE +G W G + W +L + + R R+ LPTYPF +KRYW+D + QNI +E Sbjct: 691 DLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQ---QNITNNEE 747 Query: 808 PQPGKE-NKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTIA 866 K N EW Y P W+ E + +E + + +F E E+LE+ GH + Sbjct: 748 TSIKKRSNIAEWFYTPGWMEKEIVDVTKESTKSWL-LFLDNEHIGLALKEKLERDGHRVI 806 Query: 867 RIEAGESFQQNNLS-FEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQLP 925 + G S+++ +L+ F I P P IVH W + + + L Sbjct: 807 TVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNKDLGIKTLD 866 Query: 926 EAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPLRV 985 G+Y+L+++A+ +S+ L P+ I+++ N + +V G+E+++ K+TL P++V Sbjct: 867 -------TGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKV 919 Query: 986 IPKEYENIACRLIDTDQYDHH--ILCRILSGPENNRRADWIALRNNY----IWEPAFKQ- 1038 P+EY NI CR +D D+ ++ + S + + IA+RNN I+EP + Sbjct: 920 FPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDEK 979 Query: 1039 -----VRLTTPLHAVHKRLTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLP 1093 V L + + S +A+YLA +A+++L++R+ Sbjct: 980 VSEMLVINENELASKIPNIRSKGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPD 1039 Query: 1094 EAEWDKWYAIHSGDDPVSQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGA 1153 EWD+ ++ + Q+I ++++++ + AD+ D Q+R V Q G Sbjct: 1040 REEWDEILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFGH 1099 Query: 1154 INGIIQAAGV----PDGAVIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXX 1209 ING+I AAGV +++ SR CE F K++G VL K++ +D Sbjct: 1100 INGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYD--LDFCYLVS 1157 Query: 1210 XXXXXXAPPAQVAYSAANSFLDAFAQ--INTKRGYFTQAINWDRWENTG 1256 VAYSAAN +LD+F+ NT +T +INW W+ TG Sbjct: 1158 SLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT-SINWGDWQYTG 1205 >C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I Length = 3338 Score = 701 bits (1808), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/1361 (32%), Positives = 684/1361 (50%), Gaps = 125/1361 (9%) Query: 5 TRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGV-PAEVYTKENF 63 T+ ++AIIG+ G FPGA+N+ +F+ N+K+G +SI FFTDE+L E+GV P EV + N+ Sbjct: 1373 TKEDNDIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSP-NY 1431 Query: 64 VKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIGVY 123 VKAKGYL + FD FF YTP +A MDPQ R+ HE AW ALE AGY IGVY Sbjct: 1432 VKAKGYLEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVY 1491 Query: 124 AGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACSTS 183 +G P+ +W+ LS + F I+ LNDKD +ST++SYK NLKGPS +FT CSTS Sbjct: 1492 SGASPNLYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTS 1551 Query: 184 LVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGTVV 243 LVA+H ACQ ++ G CD+A+AGG+++T P + GY +Q+GM+ SSDG CR FD ++G + Sbjct: 1552 LVAIHNACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLF 1611 Query: 244 GNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHRVA 303 G+G+G+V+LK L++A++D D I+AVIKGTAINNDG+RK+GY+APSV+GQ EVI+ A A Sbjct: 1612 GDGVGIVVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEA 1671 Query: 304 GVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQTKRKHFCGLGSVKTNIGHLDSAAGIAG 363 V+P+ I YIE HGT T LGD IE+KAL+ F + K +GSVK N+GHL++A+G+AG Sbjct: 1672 NVEPESISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAG 1731 Query: 364 LIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGPRRAGVSSFGVGG 423 LIK V A+ ++ L P+++F PN + E +PFY+ ++ EW+ + P RAGVSSFG+GG Sbjct: 1732 LIKTVFAMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGG 1791 Query: 424 TNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASADIAY 483 TNAHI+LEEAP ++ + Q+L+ SAK+++AL++ +++NP AD +Y Sbjct: 1792 TNAHIILEEAPKLEATSNSRPY-QMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASY 1850 Query: 484 TLQQGREHFSYRQYVSCRTLLAGCAAL-RVKADQALWVDPKKELKPVYFWFAGMALEEAV 542 TLQ GR+ F +R+ + C + G L + + + + K+E ++F F+G + Sbjct: 1851 TLQIGRKEFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVN 1910 Query: 543 QHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGS-----------DVYIGQTPVF 591 RE M+E + V E+L + + Q +F Sbjct: 1911 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILF 1970 Query: 592 LFQLALAKWL--------------------------------LRVGVKPAALMG------ 613 F+ A+AK L L++ VK LM Sbjct: 1971 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGV 2030 Query: 614 ------------------------TGTGAYVAGCLAGVFTLEEALMLME---KRDRLLEE 646 T + A V G V EEA++ E K+ RL+ Sbjct: 2031 MLSVPLPEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCM 2090 Query: 647 WRGSEGDLFL--LEALQSEFYEAFDSVTLSAPAIPLLSADAGS-NTVLDVTLPDYWVNAL 703 EG L+++ E+ ++TL P IP LS G+ + T P YWV + Sbjct: 2091 RVTIEGAAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHM 2150 Query: 704 GADDDGKSLPAKAEEADKHLVLHFGAAGEPSGPSGYISLVKSGPE--------------- 748 + + L + G + S + + ++G E Sbjct: 2151 RGTVRFSDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSD 2210 Query: 749 ---LLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKR 805 L + +W G + W++ K + R R+ LP Y F + Y + Q + + Sbjct: 2211 MYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSK 2270 Query: 806 QEPQPGKENKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTI 865 Q N EW Y P W S + + I VF QE ++ L G + Sbjct: 2271 QSKISKNNNISEWFYTPQWKSSTLFEPNHDVNETWI-VFVDQEGLGNELVKDLLNKGQRV 2329 Query: 866 ARIEAGESF-QQNNLSFEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQL 924 +E G +F ++NN F INPE P RI+H W + + R+ Sbjct: 2330 VTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI--TNEERQAS 2387 Query: 925 PEAEECNR-LGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPL 983 E C + LG+Y++ + +A+ + ++I I+ N V +V G+E ++P K+T+ G Sbjct: 2388 IEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTS 2447 Query: 984 RVIPKEYENIACRLID-----TDQYDHHILCRILSGPENNRRADWIALRNNYIWEPAFKQ 1038 V+P+EY ++C +D + ++ +++ +N IA R N + ++ Sbjct: 2448 LVVPQEYSYLSCSSVDVVLPLNKEGKSRLINQLIEECLSNTNDKMIAYRGNKRFVQTYEP 2507 Query: 1039 VRLTTPLHAVHKR-LTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLPEAEW 1097 ++L P A K L +AK+LA+ QA +VLL R+ EW Sbjct: 2508 LQLEQP--AKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANIVLLTRTGLPNRDEW 2565 Query: 1098 DKWYAIHSGDDPV-SQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGAING 1156 D +H ++ + S +I + EI+ S Y++ AD+TD +Q+ + ++ G ING Sbjct: 2566 D----MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKING 2621 Query: 1157 IIQAAGVPDGA---VIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXXXXXX 1213 +I AG+ G +IQ +E CE F KIYG L++ + ++ +D Sbjct: 2622 VIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLR--NKDLDFCVLMSSISA 2679 Query: 1214 XXAPPAQVAYSAANSFLDAFAQ-INTKRGYFTQAINWDRWE 1253 V+Y+A+N ++D FAQ IN ++NW W+ Sbjct: 2680 VLGGLGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWK 2720 Score = 559 bits (1441), Expect = e-156, Method: Compositional matrix adjust. Identities = 299/654 (45%), Positives = 404/654 (61%), Gaps = 8/654 (1%) Query: 2 KENTRTGLEVAIIGMSGSFPGAKNLEQFFQNVKNGVDSISFFTDEQLAEAGVPAEVYTKE 61 +++++TGLE+AIIGM+G FPGA + QF+ N+KNGVDSIS FT+++L + GV +V Sbjct: 6 QDDSKTGLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHP 65 Query: 62 NFVKAKGYLNECEYFDNSFFGYTPNEAQFMDPQTRLLHEHAWMALEDAGYPPGRTQDAIG 121 NFVKAKGYL E EYFD SFF YTP EA+ MDPQ R+L E W ALE AGY P + IG Sbjct: 66 NFVKAKGYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIG 125 Query: 122 VYAGGRPHFHWEALSLSMGSRNGTEDFEIAHLNDKDLMSTRVSYKLNLKGPSYTLFTACS 181 +Y G +F+W + + S + E E L+ KD +ST SYKL LKGPS+TL+TACS Sbjct: 126 LYVGASTNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACS 185 Query: 182 TSLVAVHAACQGVISGECDMAVAGGVSVTSPLQNGYFHQDGMILSSDGRCRAFDAASDGT 241 TSL+++H AC+ +++GEC +A AGGVS+T P +NGY + +GM S DG+ R FDA + G Sbjct: 186 TSLLSIHLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGA 245 Query: 242 VVGNGIGLVILKRLEDALDDNDHIYAVIKGTAINNDGSRKVGYSAPSVDGQAEVIRTAHR 301 V +G+G+VILKRLEDA+ D D IY VIKG+A NNDG RKVGY+APSV+GQAEVI+ AH Sbjct: 246 VFSDGVGMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHS 305 Query: 302 VAGVDPKEIGYIEAHGTGTALGDPIEVKALTTAFQ-TKRKHFCGLGSVKTNIGHLDSAAG 360 A VDP I YIE HGT T LGD IEV+AL AFQ +K FC +GSVK+N+GHLD+AAG Sbjct: 306 FAEVDPSTISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAG 365 Query: 361 IAGLIKAVLALHNKCLLPTLHFANPNPHLMLEDSPFYLVDRMREWENGSGP-RRAGVSSF 419 + GLIK VL++ +K L PTL+ PN + DSPFY+ + W++ RAGVS+F Sbjct: 366 VTGLIKTVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAF 425 Query: 420 GVGGTNAHIVLEEAPSGQSVKQAEAQEQLLVFSAKTREALEQSIEAFVQDVQKNPGKASA 479 G GGTN HIVLEEAP +S + +++L+V SA+++EAL + V+ ++ N A Sbjct: 426 GYGGTNVHIVLEEAPKVKS-SASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELA 484 Query: 480 DIAYTLQQGREHFSYRQYVSCRTLLAGCAALRVKADQALWVDPKKELKPVYFWFAGMALE 539 D+AYTLQ GR F YR+ V C+ + + L+ D + +L V +E Sbjct: 485 DVAYTLQTGRRSFPYRRAVLCKDIDSAIDNLKTVKDFHVKTQENPDLVFVLPSEYSSIIE 544 Query: 540 EAVQHYHSCLHHPYCREEMEELLLQASGIRGVKRDELLSGGSDVYIGQTPVFLFQL-ALA 598 + Y P + E + A G E G+D + + F L ++ Sbjct: 545 NVKELYQK---EPLFLKVFERNMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSII 601 Query: 599 KWLLRVGVKPAALMGTGTGAYVAGCLAGVFTLEEALM-LMEKRDRLLEEWRGSE 651 L+ V+P+ ++GTG V+ E+ L L+E L EW E Sbjct: 602 DVLIECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNPLVENYIELQIEWTHGE 655 Score = 379 bits (973), Expect = e-102, Method: Compositional matrix adjust. Identities = 199/606 (32%), Positives = 343/606 (56%), Gaps = 13/606 (2%) Query: 1586 ALTPEEGLMILDAALSTAYPQVIV-STVDLPARVEAYRNEKVNLYQDNGGSSAADKVQAS 1644 ++TPEEG+ + ALS +V++ S +L AR++ + +N + D + S Sbjct: 2739 SMTPEEGVQAFNIALSWKQGEVLIHSPGELQARIDQWV--LLNSFNDEKEEELDSTLYHS 2796 Query: 1645 GVNMSAE------ELEHVIRSIWQSVLGHEQISREDDFFDLGGDSLKVLTVAERIYQAVN 1698 + E E+E + IW+++ ++ DD +LGGDSLK +T+ +I++ N Sbjct: 2797 RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEFN 2856 Query: 1699 IKIPVSVFFHTTVLNELARHIQAASHTTNEYAAIQKAAPGAYYPLSSAQKRLYFQQQLQP 1758 +++P+ F + + +LA +I A + E+ I A P ++Y LSSAQKR Y +L P Sbjct: 2857 VEVPIKELFTLSNIEKLANYISRADKS--EFDVIVPAEPKSHYQLSSAQKRFYVLHRLYP 2914 Query: 1759 DSVAYNILEITSVEGNLDPGKLQNAFDLLIQRHAVLRTSFDVINGEIVQIIHDRAEFQVE 1818 +S AYN + + G L+ +L+ AF LI+RH + RT+ ++ N + VQIIHD A+F + Sbjct: 2915 ESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHIT 2974 Query: 1819 HVTVKXXXXXXXXXXFMQPFDLRSAPLLRVKIVRCGMQKYVWLFDIHHIIADNLSVEILK 1878 + F++PF+ +AP RV ++R QK++ + D+HHI+ D +S +I Sbjct: 2975 QIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFV 3034 Query: 1879 SELISIYNGQADQLKPILLEYVDFVGWQNEQIRRGKFDKQTEYWLQQLSGELPESRLPAD 1938 +L ++Y+G+ +L + ++Y D+ WQ + + K +YWL+Q +P +P D Sbjct: 3035 RDLFALYSGE--KLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLEQFKDGVPVLNMPTD 3092 Query: 1939 YPRPAVLSHQGDIYTFTLDETVTGRLKQGMKRNTTTLFMNMMALFSVLLQKYTGQDEVMI 1998 Y RP ++ +G +FT+D VT ++K+ + + TTL+ M++++++LL KYTGQ++V+I Sbjct: 3093 YTRPEIIDLKGSKISFTIDSNVTKKIKRLLAKEETTLYTLMLSVYNILLGKYTGQEDVVI 3152 Query: 1999 GASLAGRNHADLADMVGMFANVLPFRSRINRDGSFEQLLTEVKTQSLQIFENQDVQFEVL 2058 G+ + GR HADL D++G+F N+L R+ + F Q L EVK Q LQ FE+Q Q+E L Sbjct: 3153 GSPITGRPHADLQDIIGVFVNMLGIRNYPRAEQRFTQFLFEVKEQVLQAFEHQKCQYEDL 3212 Query: 2059 VEALGRSHQLSENPLFNVMLVLPDVAPAEAAMDQVRLQAYPFCNPSSKFDLTLWVYDYDD 2118 V LG + NPLF+V V+ ++ +D + L+ Y ++ DL L V + +D Sbjct: 3213 VNQLGLQGTYNRNPLFDVSFVMQNMDADHMFIDGLELRTYDHDFKRAQMDLLLRVVELED 3272 Query: 2119 SIEMRMEYSTDLFARKTIITMCRHLLDIASLVAGNPDILIKEIMLDSGLVRTEALDLLDD 2178 +IE+ MEY+T L+ R T+ +C ++I + +P+IL+K+I + + + + D Sbjct: 3273 TIELTMEYATSLYTRDTVQKLCERYVEIFEQIVDHPEILLKDISFKQEIQELQPVKVSVD 3332 Query: 2179 GNDFAF 2184 DF F Sbjct: 3333 FGDFNF 3338 Score = 214 bits (546), Expect = 7e-53, Method: Compositional matrix adjust. Identities = 150/529 (28%), Positives = 250/529 (47%), Gaps = 34/529 (6%) Query: 748 ELLETVGCIWANGYPLQWDELAKHQNRARVILPTYPFTRKRYWVDTQQIKQFQNIWKRQE 807 +LLE +G W G + W +L + + R R+ LPTYPF +KRYW+D + QNI +E Sbjct: 693 DLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQ---QNITNSEE 749 Query: 808 PQPGKE-NKEEWMYVPSWIRSEYMPEEREQQQGLIAVFATQEPFVARCIERLEQMGHTIA 866 K N EW Y P W+ E + +E + + +F E E+LE+ GH + Sbjct: 750 TSIKKRSNIAEWFYTPGWMEKEIVDVTKESTKSWL-LFLDNEHIGLALKEKLERDGHRVI 808 Query: 867 RIEAGESFQQNNLS-FEINPEXXXXXXXXXXXXXXXGDGPVRIVHFWCMHPQSAAREQLP 925 + G S+++ +L+ F I P P IVH W + + E L Sbjct: 809 TVGVGPSYKKISLNEFTICPTKQEDYYQLFNELQKQECLPEEIVHLWNVDNKDLGIETLD 868 Query: 926 EAEECNRLGYYTLLNIARAVSQLQLQQPVTIDIVANQVAEVTGNETVVPAKATLFGPLRV 985 G+Y+L+++A+ +S+ L P+ I+++ N + +V G+E+++ K+TL P++V Sbjct: 869 -------TGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKV 921 Query: 986 IPKEYENIACRLIDTDQYDHH--ILCRILSGPENNRRADWIALRNNY----IWEPAFKQ- 1038 P+EY NI CR +D D+ ++ + S + + IA+RNN I+EP + Sbjct: 922 FPQEYPNIRCRSVDFMLSDNEEALISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDEK 981 Query: 1039 -----VRLTTPLHAVHKRLTSXXXXXXXXXXXXXXXHVAKYLAEQYQAQVVLLNRSQFLP 1093 V L + + S +A+YLA +A+++L++R+ Sbjct: 982 VSEMLVINENELASKIPNIRSEGIYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPD 1041 Query: 1094 EAEWDKWYAIHSGDDPVSQKIASLREIKAAASGFYLVQADITDAAQVRAVFGQILERCGA 1153 EWD+ ++ + Q+I ++++++ + AD+ D Q+R V Q G Sbjct: 1042 REEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQTEANFGH 1101 Query: 1154 INGIIQAAGV----PDGAVIQRRSREMCEAVFGTKIYGTQVLQKVIGELSRPVDXXXXXX 1209 ING+I AAGV +++ SR CE F K++G VL K++ +D Sbjct: 1102 INGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYD--LDFCYLVS 1159 Query: 1210 XXXXXXAPPAQVAYSAANSFLDAFAQ--INTKRGYFTQAINWDRWENTG 1256 VAYSAAN +LD+F+ NT +T +INW W+ TG Sbjct: 1160 SLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT-SINWGDWQYTG 1207 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.404 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 12,852,239,019 Number of extensions: 543064839 Number of successful extensions: 1410443 Number of sequences better than 1.0e-05: 12223 Number of HSP's gapped: 1353917 Number of HSP's successfully gapped: 17845 Length of query: 2184 Length of database: 3,060,696,203 Length adjustment: 152 Effective length of query: 2032 Effective length of database: 1,628,701,923 Effective search space: 3309522307536 Effective search space used: 3309522307536 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 140 (58.5 bits)