BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0026.p (1557 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase 723 0.0 C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I 722 0.0 C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I 721 0.0 C3I386.1 C3I386_BACTU Polyketide synthase type I 720 0.0 C3FU99.1 C3FU99_BACTB Polyketide synthase type I 719 0.0 >B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase Length = 3336 Score = 723 bits (1867), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/1387 (32%), Positives = 714/1387 (51%), Gaps = 85/1387 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 LEIA+IG+AG+FPGA I+++WDNLKNGV S+ TF+E ELI GV + +VKAKG Sbjct: 11 LEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAKG 70 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 YLE FD FF YTP EA++MDPQ+++ E W + LIGL+ GAS Sbjct: 71 YLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAST 130 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVH 180 N W L V+ A L KD +S ++KL LKGP+ ++YTACSTSL+++H Sbjct: 131 NFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSIH 190 Query: 181 MAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXX 240 +A +SLL GEC IA AGGV++T P+K+GY+Y EGM SPDGK R F Sbjct: 191 LACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGVG 250 Query: 241 XXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPD 300 +LKRL+DA+ DGD IY VIKGSA NNDG +K G+TAPS GQAEVI+ A AEV P Sbjct: 251 MVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDPS 310 Query: 301 SIDYIECHGTGTPLGDPIELEALELGY-NPERRHACALGSVKTNIGHLDSAAGIASFIKT 359 +I Y+E HGT TPLGD IE+EAL+ + + +++ CA+GSVK+N+GHLD+AAG+ IKT Sbjct: 311 TISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIKT 370 Query: 360 VLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEP-LRAGISAFGIGGTNA 418 VL+++H LPP+L+ + PN + I+ FYIN L W S+++ LRAG+SAFG GGTN Sbjct: 371 VLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDKDLLRAGVSAFGYGGTNV 430 Query: 419 HIIVEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQV 477 HI++E+AP + +++ RE +L+ +SA++ AL ++ +Y ++ L D+AYTLQ Sbjct: 431 HIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELADVAYTLQT 490 Query: 478 GRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 GR+ FP R A++ + + +T EN ++FV+P Sbjct: 491 GRRSFPYRR-AVLCKDIDSAIDNLKTVKDFHVKTQENPDLVFVLP-----SEYSSIIENV 544 Query: 538 XXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKRE---YHPVLAFGSYYAVGKLF 594 P + + M + + G A+K + + + F ++ + Sbjct: 545 KELYQKEPLFLKVFER--NMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSIIDVL 602 Query: 595 IEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVRSFLLSLDECGM-----ERPEAGRRSS 649 IE + P +IG G + ++ + L E+ + + + E E+ E + Sbjct: 603 IECDVRPSNIIGTGLAGMISDIYNKSLKPEDVLNQLVENYTELQTEWTHGEKVELLTQVK 662 Query: 650 RREEIWLVLGAGNEAQPFLDKQSSKPQIIALEKLNTYSLMAAVGTMWLYGQDIKWRELYQ 709 + ++++ G L+ + + QII L+ +G W G +I W +LY+ Sbjct: 663 DVDPNYVIVHIGE----LLNSEINNNQIILQN-----DLLEVLGQAWELGVEINWSKLYE 713 Query: 710 HEQRNRLSLPTYAFDRQEFPVDP-ELFNLNHLLNRPPSGKGGTPADRDDIRKWFYIPAWE 768 E R R++LPTY F+++ + +DP E N+ + + + R +I +WFY P W Sbjct: 714 EEYRLRIALPTYPFEKKRYWIDPAEQQNITN-------SEETSIKKRSNIAEWFYTPGWM 766 Query: 769 SAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRCIMVEHAEHYQQITADHYR 828 + + + +W +F D +G AL + L + R I V Y++I+ + + Sbjct: 767 EKEIVDV---IKGSTKSWLLFLDNEHIGLALKEKLERDGHRVITVGVGPSYKKISLNEFT 823 Query: 829 VNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELANIETGQQLFLHHILRLVQF 885 + P E+ +L++ L + +P+ I +LW V + + + ++TG + ++ L + Sbjct: 824 ICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK-DLGIETLDTG----FYSLISLAKT 878 Query: 886 LGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIPYEYPNIKVCHVDFPLAE 945 + +++ +++N + + +E + K LL K+ P EYPNI+ VDF L++ Sbjct: 879 ISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSD 938 Query: 946 GDPARQREQARQMLREFQFEFPNKQVAYRGKSRWI--------EAVQKPLLLA---SPGK 994 + A + E Q + + +A R +R+I E V + L++ S K Sbjct: 939 NEEAL----ISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDEKVSEMLVIKENESASK 994 Query: 995 VSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWM-NRPDDA 1053 + R+ V +IT A+L+LV R+A P + EWDQ + ++ ++ Sbjct: 995 IPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPDREEWDQILQSQIENE 1054 Query: 1054 EVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAGVADYAG 1113 ++ + I I+ LE+ GA + AD++D M+ V+ +AEA G I GV+H AGV Sbjct: 1055 QLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFGHINGVIHAAGVLRVKS 1114 Query: 1114 V---IQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFGQVGYN 1170 +++ ++ +E LPKV G LVLD L N LDF L SS+ + G G V Y+ Sbjct: 1115 AQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFCYLVSSLSPILGG--LGFVAYS 1172 Query: 1171 AANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFEAEAIT 1230 AAN +LD+F +INW DW G ++K N EA +T Sbjct: 1173 AANLYLDSFSDKVSNTSNNRWTSINWGDWQYTG--------TEQVNKIFNAQSIEALEMT 1224 Query: 1231 TEQGVNVFRYIME-NQMNRVIVSALDLPALMEESNNISVEVILEQXXXXXXXXXXXXXXG 1289 +E+G F+ ++ + +N+VI+S+ DL ++ N++ + + Sbjct: 1225 SEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISELETQTKT-------- 1276 Query: 1290 SSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLVFKKLGVKLPL 1349 + +++ I IW ++ + ++E+FF LG SL I I + +L + + Sbjct: 1277 GDKFRNQDEVEEIIIGIWKEFYSVDTVNVNENFFDLGATSLHIIQIHERLINRLEKHISI 1336 Query: 1350 PAFFHKP 1356 F P Sbjct: 1337 GVMFEYP 1343 Score = 540 bits (1392), Expect = e-151, Method: Compositional matrix adjust. Identities = 283/644 (43%), Positives = 389/644 (60%), Gaps = 24/644 (3%) Query: 2 EIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGY 61 +IA+IG+ GRFPGA ++E+W+N+K+G S+Q F+++ELI +GV P YVKAKGY Sbjct: 1376 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1435 Query: 62 LEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPN 121 LE FDA FFDYTP +A LMDPQ++VFHEC W LIG+++GASPN Sbjct: 1436 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1495 Query: 122 HVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVHM 181 W+ L LS + G + S L DKD LS +I++K NLKGP+++I+T CSTSLVA+H Sbjct: 1496 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1555 Query: 182 AAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXXX 241 A Q+LL G CDIA+AGG+T+T PEK+GY YQEGM+ S DG CR F Sbjct: 1556 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1615 Query: 242 XVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPDS 301 VLK LQ+A++DGD I+AVIKG+A+NNDG +K G+TAPS GQ EVI+ A A V P+S Sbjct: 1616 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1675 Query: 302 IDYIECHGTGTPLGDPIELEALELGYNPERRHACALGSVKTNIGHLDSAAGIASFIKTVL 361 I YIE HGT T LGD IE++AL +N + + +GSVK N+GHL++A+G+A IKTV Sbjct: 1676 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1735 Query: 362 ALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGGTNAHII 421 A+K +LPPS++F PN + + FY+N RL EW N+PLRAG+S+FGIGGTNAHII Sbjct: 1736 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGGTNAHII 1795 Query: 422 VEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQVGRK 480 +E+AP S R +Q+L +SAK+ AL + +L + + P L D +YTLQ+GRK Sbjct: 1796 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSYTLQIGRK 1855 Query: 481 HFPIRE----------LALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXX 530 F R + L+N+ R +Q+ E+ V F+ + Sbjct: 1856 EFKHRRALVCSSTQEGIELLNQPEGRRVQYVNVKE-------EHPKVNFLFSGNGSQYVN 1908 Query: 531 XXXXXXXXXXXXXXPGARRF--LNQV--LGMMNRLVPDGAAVK--LEDLRKREYHPVLAF 584 F L V + M L P ++ E L++ E+ + F Sbjct: 1909 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILF 1968 Query: 585 GSYYAVGKLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVR 628 YAV KL + WG+ PEA+IG +++AACL+ +LE+A++ Sbjct: 1969 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALK 2012 Score = 346 bits (887), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 241/864 (27%), Positives = 410/864 (47%), Gaps = 50/864 (5%) Query: 684 NTYSLMAAVGTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNR 743 + Y L + + MW+ G + W + Y+ E+R R+ LP Y+F++ + + ++L LN Sbjct: 2208 DMYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLN- 2266 Query: 744 PPSGKGGTPADRDDIRKWFYIPAWESAAL--PNYEGRMLSRDAAWFIFCDPGGLG-EALG 800 K + ++I +WFY P W+S+ L PN++ + W +F D GLG E + Sbjct: 2267 ---SKQSKISKNNNISEWFYTPQWKSSTLFEPNHD-----VNETWIVFVDQEGLGNELVK 2318 Query: 801 DLLRQQQIRCIMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSLDAV---PDHICYLWTV 857 DLL + Q R + VE + + D + +NP + +L + + P I ++W + Sbjct: 2319 DLLNKGQ-RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI 2377 Query: 858 TSPMEPELANIE---TGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLC 914 T+ E A+IE Q L + + L Q LG + + ++I++NG+ + +E L Sbjct: 2378 TN--EERQASIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELI 2435 Query: 915 PMKGLLLGASKIIPYEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQFEFPNKQVAYR 974 P K +LG S ++P EY + VD L + R Q++ E +K +AYR Sbjct: 2436 PEKSTVLGTSLVVPQEYSYLSCSSVDVVLPLNKEWKSR-LINQLVEECLSNTNDKMIAYR 2494 Query: 975 GKSRWIEAVQKPLLLASPGKVSL-FRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVG 1033 G R+++ + PL L P K L R N V +IT A LVL+ Sbjct: 2495 GNKRFVQTYE-PLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLT 2553 Query: 1034 RSAFPPKSEWDQWMNRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAE 1093 R+ P + EWD M+ ++ + IR + +E G+ + V +AD++D S + + + +AE Sbjct: 2554 RTGLPNRDEWD--MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAE 2611 Query: 1094 ARLGPITGVLHTAGV--ADYAGVIQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVL 1151 + G I GV+H AG+ +IQ + +E K+ G L L+ RN+ LDF VL Sbjct: 2612 QKFGKINGVIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVL 2671 Query: 1152 FSSIGNYIYGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEK 1211 SSI + G G V Y A+N ++D F Y + ++NW+DW K M+ Sbjct: 2672 MSSISAVLGG--LGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWKYWEDEEKDMQI 2729 Query: 1212 NRSLHKAVNDLQFEAEAITTEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEVI 1271 S+H+ ++T E+GV F + + V++ + P ++ I V+ Sbjct: 2730 GASVHEL---------SMTPEEGVQAFNIALSWKQGEVLIHS---PGELQA--RIDQWVL 2775 Query: 1272 LEQXXXXXXXXXXXXXXGSS-SLLTE-----AGLQQQIADIWSTVLGIEAIGIDEDFFAL 1325 L S LLTE ++++++ IW + + +G+ +D L Sbjct: 2776 LNSFNDEKEEELDSTLYHSRPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLEL 2835 Query: 1326 GGDSLKAITIVSLVFKKLGVKLPLPAFFHKPXXXXXXXXXXXXXXXDYARIKRAPQKEGY 1385 GGDSLKAITIVS + K+ V++P+ F ++ I A K Y Sbjct: 2836 GGDSLKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSYY 2895 Query: 1386 PLTPGQKRLYFLSQMEQENKQYNNIIALQVNGPLDFGKLEACLKQLIRRHESLRTCFRRI 1445 L+ QKR Y L ++ E+ YN+ + +NG L+ +LE QLI+RHE RT Sbjct: 2896 QLSSAQKRFYVLHRLYPESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMK 2955 Query: 1446 GGEWVQWIEEEVQLALDVVDIKGTVNDKHIEAWIQAFDLAAAPLWKIGVFKEGEHRHLIV 1505 + VQ I + + ++ + ++ I +I+ F+ AP +++G+ + E +H+++ Sbjct: 2956 NDKPVQIIHDHADFHITQIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILI 3015 Query: 1506 FNIHHIITDGTSNAILIDEFTTLY 1529 ++HHI+TDG S I + + LY Sbjct: 3016 IDLHHIVTDGVSYDIFVRDLFALY 3039 >C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I Length = 3338 Score = 722 bits (1863), Expect = 0.0, Method: Compositional matrix adjust. Identities = 446/1387 (32%), Positives = 714/1387 (51%), Gaps = 85/1387 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 LEIA+IG+AG+FPGA I+++WDNLKNGV S+ TF+E ELI GV + +VKAKG Sbjct: 13 LEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAKG 72 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 YLE FD FF YTP EA++MDPQ+++ E W + LIGL+ GAS Sbjct: 73 YLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAST 132 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVH 180 N W L V+ A L KD +S ++KL LKGP+ ++YTACSTSL+++H Sbjct: 133 NFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSIH 192 Query: 181 MAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXX 240 +A +SLL GEC IA AGGV++T P+K+GY+Y EGM SPDGK R F Sbjct: 193 LACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGVG 252 Query: 241 XXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPD 300 +LKRL+DA+ DGD IY VIKGSA NNDG +K G+TAPS GQAEVI+ A AEV P Sbjct: 253 MVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDPS 312 Query: 301 SIDYIECHGTGTPLGDPIELEALELGY-NPERRHACALGSVKTNIGHLDSAAGIASFIKT 359 +I YIE HGT TPLGD IE+EAL+ + + +++ CA+GSVK+N+GHLD+AAG+ IKT Sbjct: 313 TISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIKT 372 Query: 360 VLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSK-NEPLRAGISAFGIGGTNA 418 VL+++H LPP+L+ + PN + I+ FYIN L W S+ N+ LRAG+SAFG GGTN Sbjct: 373 VLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTNV 432 Query: 419 HIIVEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQV 477 HI++E+AP + +++ RE +L+ +SA++ AL ++ Y ++ L D+AYTLQ Sbjct: 433 HIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTLQT 492 Query: 478 GRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 GR+ FP R A++ + + +T EN ++FV+P Sbjct: 493 GRRSFPYRR-AVLCKDIDSAIDNLKTVKDFHVKTQENPDLVFVLP-----SEYSSIIENV 546 Query: 538 XXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKRE---YHPVLAFGSYYAVGKLF 594 P + + M + + G A+K + + + F ++ + Sbjct: 547 KELYQKEPLFLKVFER--NMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSIIDVL 604 Query: 595 IEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVRSFL-----LSLDECGMERPEAGRRSS 649 IE + P +IG G + ++ + L E+ + + L ++ E+ E + Sbjct: 605 IECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNPLVENYIELQIEWTHGEKVELLTQVK 664 Query: 650 RREEIWLVLGAGNEAQPFLDKQSSKPQIIALEKLNTYSLMAAVGTMWLYGQDIKWRELYQ 709 + ++++ G L+ + + QII L+ +G W G +I W +LY+ Sbjct: 665 DVDPNFVIVHIGE----LLNSEINNNQIILQN-----DLLEVLGQAWELGVEINWSKLYE 715 Query: 710 HEQRNRLSLPTYAFDRQEFPVDP-ELFNLNHLLNRPPSGKGGTPADRDDIRKWFYIPAWE 768 E R R++LPTY F+++ + +DP E N+ + + + R +I +WFY P W Sbjct: 716 EEYRLRIALPTYPFEKKRYWIDPAEQQNITN-------SEETSIKKRSNIAEWFYTPGWM 768 Query: 769 SAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRCIMVEHAEHYQQITADHYR 828 + + +W +F D +G AL + L + R I V Y++I+ + + Sbjct: 769 EKEIVDVTKE---STKSWLLFLDNEHIGLALKEKLERDGHRVITVGVGPSYKKISLNEFT 825 Query: 829 VNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELANIETGQQLFLHHILRLVQF 885 + P + E+ +L++ L + +P+ I +LW V + + + ++TG + ++ L + Sbjct: 826 ICPTKQEDYYQLFNELQKQECLPEEIVHLWNVDNK-DLGIETLDTG----FYSLISLAKT 880 Query: 886 LGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIPYEYPNIKVCHVDFPLAE 945 + +++ +++N + + +E + K LL K+ P EYPNI+ VDF L++ Sbjct: 881 ISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSD 940 Query: 946 GDPARQREQARQMLREFQFEFPNKQVAYRGKSRWI--------EAVQKPLLLAS---PGK 994 + A + E Q + + +A R +R+I E V + L++ K Sbjct: 941 NEEAL----ISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDEKVSEMLVINENELASK 996 Query: 995 VSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWM-NRPDDA 1053 + R+ + +IT A+L+LV R+A P + EWDQ + ++ ++ Sbjct: 997 IPNIRSEGIYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPDREEWDQILQSQIENE 1056 Query: 1054 EVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAGVADYAG 1113 ++ + I I+ LE+ GA + AD++D M+ V+ + EA G I GV+H AGV Sbjct: 1057 QLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQTEANFGHINGVIHAAGVLRVKS 1116 Query: 1114 V---IQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFGQVGYN 1170 +++ ++ +E LPKV G LVLD L N LDF L SS+ + G G V Y+ Sbjct: 1117 AQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFCYLVSSLSPILGG--LGFVAYS 1174 Query: 1171 AANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFEAEAIT 1230 AAN +LD+F +INW DW G + ++K N EA +T Sbjct: 1175 AANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGA--------QQVNKIFNAQSIEALEMT 1226 Query: 1231 TEQGVNVFRYIME-NQMNRVIVSALDLPALMEESNNISVEVILEQXXXXXXXXXXXXXXG 1289 +E+G F+ ++ + +N+VI+S+ DL ++ N++ + + Sbjct: 1227 SEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISELETQTKT-------- 1278 Query: 1290 SSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLVFKKLGVKLPL 1349 + +++ I IW ++ + ++E+FF LG SL I I + +L ++ + Sbjct: 1279 GDKFRNQDEVEEIIIGIWKEFYSVDTVNVNENFFDLGATSLHIIQIHERLINRLEKQISI 1338 Query: 1350 PAFFHKP 1356 F P Sbjct: 1339 GVMFEYP 1345 Score = 537 bits (1384), Expect = e-150, Method: Compositional matrix adjust. Identities = 278/637 (43%), Positives = 387/637 (60%), Gaps = 10/637 (1%) Query: 2 EIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGY 61 +IA+IG+ GRFPGA ++E+W+N+K+G S+Q F+++ELI +GV P YVKAKGY Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1437 Query: 62 LEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPN 121 LE FDA FFDYTP +A LMDPQ++VFHEC W LIG+++GASPN Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 122 HVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVHM 181 W+ L LS + G + S L DKD LS +I++K NLKGP+++I+T CSTSLVA+H Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 182 AAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXXX 241 A Q+LL G CDIA+AGG+T+T PEK+GY YQEGM+ S DG CR F Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 242 XVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPDS 301 VLK LQ+A++DGD I+AVIKG+A+NNDG +K G+TAPS GQ EVI+ A A V P+S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 302 IDYIECHGTGTPLGDPIELEALELGYNPERRHACALGSVKTNIGHLDSAAGIASFIKTVL 361 I YIE HGT T LGD IE++AL +N + + +GSVK N+GHL++A+G+A IKTV Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 362 ALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGGTNAHII 421 A+K +LPPS++F PN + + FY+N +L EW N+PLRAG+S+FGIGGTNAHII Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 422 VEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQVGRK 480 +E+AP S R +Q+L +SAK+ AL + +L + + P L D +YTLQ+GRK Sbjct: 1798 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGRK 1857 Query: 481 HFPIRELALVNRKSQRVLQFAETATMK---GTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 F R + + + + Q + + E+ + F+ + Sbjct: 1858 EFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVNMGLELYE 1917 Query: 538 XXXXXXXPGARRF--LNQV--LGMMNRLVPDGAAVK--LEDLRKREYHPVLAFGSYYAVG 591 F L V + M L P ++ E L++ E+ + F YAV Sbjct: 1918 QEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILFAFEYAVA 1977 Query: 592 KLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVR 628 KL + WG+ PEA+IG +++AACL+ +LE+A++ Sbjct: 1978 KLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALK 2014 Score = 347 bits (889), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 240/864 (27%), Positives = 410/864 (47%), Gaps = 50/864 (5%) Query: 684 NTYSLMAAVGTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNR 743 + Y L + + MW+ G + W + Y+ E+R R+ LP Y+F++ + + ++L LN Sbjct: 2210 DMYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLN- 2268 Query: 744 PPSGKGGTPADRDDIRKWFYIPAWESAAL--PNYEGRMLSRDAAWFIFCDPGGLG-EALG 800 K + ++I +WFY P W+S+ L PN++ + W +F D GLG E + Sbjct: 2269 ---SKQSKISKNNNISEWFYTPQWKSSTLFEPNHD-----VNETWIVFVDQEGLGNELVK 2320 Query: 801 DLLRQQQIRCIMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSLDAV---PDHICYLWTV 857 DLL + Q R + VE + + D + +NP + +L + + P I ++W + Sbjct: 2321 DLLNKGQ-RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI 2379 Query: 858 TSPMEPELANIE---TGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLC 914 T+ E A+IE Q L + + L Q LG + + ++I++NG+ + +E L Sbjct: 2380 TN--EERQASIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELI 2437 Query: 915 PMKGLLLGASKIIPYEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQFEFPNKQVAYR 974 P K +LG S ++P EY + VD L + R Q++ E +K +AYR Sbjct: 2438 PEKSTVLGTSLVVPQEYSYLSCSSVDVVLPLNKEGKSR-LINQLIEECLSNTNDKMIAYR 2496 Query: 975 GKSRWIEAVQKPLLLASPGKVSL-FRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVG 1033 G R+++ + PL L P K L R N V +IT A +VL+ Sbjct: 2497 GNKRFVQTYE-PLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANIVLLT 2555 Query: 1034 RSAFPPKSEWDQWMNRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAE 1093 R+ P + EWD M+ ++ + IR + +E G+ + V +AD++D S + + + +AE Sbjct: 2556 RTGLPNRDEWD--MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAE 2613 Query: 1094 ARLGPITGVLHTAGV--ADYAGVIQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVL 1151 + G I GV+H AG+ +IQ + +E K+ G L L+ RN+ LDF VL Sbjct: 2614 QKFGKINGVIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVL 2673 Query: 1152 FSSIGNYIYGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEK 1211 SSI + G G V Y A+N ++D F Y + ++NW+DW K M+ Sbjct: 2674 MSSISAVLGG--LGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWKYWEDEEKDMQI 2731 Query: 1212 NRSLHKAVNDLQFEAEAITTEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEVI 1271 S+H+ ++T E+GV F + + V++ + P ++ I V+ Sbjct: 2732 GASVHEL---------SMTPEEGVQAFNIALSWKQGEVLIHS---PGELQA--RIDQWVL 2777 Query: 1272 LEQXXXXXXXXXXXXXXGSS-SLLTE-----AGLQQQIADIWSTVLGIEAIGIDEDFFAL 1325 L S LLTE ++++++ IW + + +G+ +D L Sbjct: 2778 LNSFNDEKEEELDSTLYHSRPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLEL 2837 Query: 1326 GGDSLKAITIVSLVFKKLGVKLPLPAFFHKPXXXXXXXXXXXXXXXDYARIKRAPQKEGY 1385 GGDSLKAITIVS + K+ V++P+ F ++ I A K Y Sbjct: 2838 GGDSLKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHY 2897 Query: 1386 PLTPGQKRLYFLSQMEQENKQYNNIIALQVNGPLDFGKLEACLKQLIRRHESLRTCFRRI 1445 L+ QKR Y L ++ E+ YN+ + +NG L+ +LE QLI+RHE RT Sbjct: 2898 QLSSAQKRFYVLHRLYPESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMK 2957 Query: 1446 GGEWVQWIEEEVQLALDVVDIKGTVNDKHIEAWIQAFDLAAAPLWKIGVFKEGEHRHLIV 1505 + VQ I + + ++ + ++ I +I+ F+ AP +++G+ + E +H+++ Sbjct: 2958 NDKPVQIIHDHADFHITQIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILI 3017 Query: 1506 FNIHHIITDGTSNAILIDEFTTLY 1529 ++HHI+TDG S I + + LY Sbjct: 3018 IDLHHIVTDGVSYDIFVRDLFALY 3041 >C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I Length = 3339 Score = 721 bits (1861), Expect = 0.0, Method: Compositional matrix adjust. Identities = 453/1387 (32%), Positives = 709/1387 (51%), Gaps = 84/1387 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 LEIA+IG+AG+FPGA I+++WDNLKNGV S+ TF+E ELI GV + +VKAKG Sbjct: 13 LEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLEVLQHPNFVKAKG 72 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 YLE FD FF YTP EA++MDPQ+++ E W + LIGL+ GAS Sbjct: 73 YLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAST 132 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVH 180 N W L V+ A L KD +S ++KL LKGP+ ++YTACSTSL+++H Sbjct: 133 NFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSIH 192 Query: 181 MAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXX 240 +A +SLL GEC IA AGGV++T P+K+GY+Y EGM SPDGK R F Sbjct: 193 LACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGVG 252 Query: 241 XXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPD 300 +LKRL+DA+ DGD IY VIKGSA NNDG +K G+TAPS GQAEVI+ A AEV P Sbjct: 253 MVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDPS 312 Query: 301 SIDYIECHGTGTPLGDPIELEALELGY-NPERRHACALGSVKTNIGHLDSAAGIASFIKT 359 +I YIE HGT TPLGD IE+EAL+ + + +++ CA+GSVK+N+GHLD+AAG+ IKT Sbjct: 313 TISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIKT 372 Query: 360 VLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSK-NEPLRAGISAFGIGGTNA 418 VL+++H LPP+L+ + PN + I+ FYIN L W S+ N+ LRAG+SAFG GGTN Sbjct: 373 VLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTNV 432 Query: 419 HIIVEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQV 477 HI++E+AP + +++ RE +L+ +SA++ AL ++ Y ++ L D+AYTLQ Sbjct: 433 HIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTLQT 492 Query: 478 GRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 GR+ FP R A++ + + +T EN ++FV+P Sbjct: 493 GRRSFPYRR-AVLCKDIDSAIDNLKTVKDFHVKTQENPDLVFVLPSEYSSIIENVKELYQ 551 Query: 538 XXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKRE---YHPVLAFGSYYAVGKLF 594 R M + + G A+K + + + F ++ + Sbjct: 552 KEPLFLQVFER-------NMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSIIDVL 604 Query: 595 IEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVRSFLLSLDECGM-----ERPEAGRRSS 649 IE + P +IG G + ++ + L E+ + + + E E+ E + Sbjct: 605 IECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNPLVENYIELQTEWTHGEKVELLTQVK 664 Query: 650 RREEIWLVLGAGNEAQPFLDKQSSKPQIIALEKLNTYSLMAAVGTMWLYGQDIKWRELYQ 709 + ++++ G L+ + + QII L+ +G W G +I W +LY+ Sbjct: 665 DVDPNFVIVHIGE----LLNSEINNNQIILQN-----DLLEVLGQAWELGVEINWSKLYE 715 Query: 710 HEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNRPPSGKGGTPADRDDIRKWFYIPAW-E 768 E R R++LPTY F+++ + +DP N S + + R +I KWFY P W E Sbjct: 716 EEYRLRIALPTYPFEKKRYWIDPA-----EQQNITNSEEETSIKKRSNIAKWFYTPGWME 770 Query: 769 SAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRCIMVEHAEHYQQITADHYR 828 + +G S W +F D +G AL + L + R I V Y++I+ + + Sbjct: 771 KEIVDVTKGSTKS----WLLFLDNEHIGLALKEKLERDGHRVITVGVGPSYKKISLNEFT 826 Query: 829 VNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELANIETGQQLFLHHILRLVQF 885 + P E+ +L++ L + +P+ I +LW V + + + ++TG + ++ L + Sbjct: 827 ICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK-DLGIETLDTG----FYSLISLAKT 881 Query: 886 LGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIPYEYPNIKVCHVDFPLAE 945 + +++ +++N + + +E + K LL K+ P EYPNI+ VDF L++ Sbjct: 882 ISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSD 941 Query: 946 GDPARQREQARQMLREFQFEFPNKQVAYRGKSRWI--------EAVQKPLLL---ASPGK 994 + A + E Q + + +A R +R+I E V + L++ S K Sbjct: 942 NEEAL----ISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDEKVSEMLVINENESASK 997 Query: 995 VSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWM-NRPDDA 1053 + R+ V +IT A+L+LV R+A P + EWDQ + ++ ++ Sbjct: 998 IPNIRSEGVYLITGGIGGVGLKLAEYLARTVKAKLILVSRTALPDREEWDQILQSQIENE 1057 Query: 1054 EVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAGVADYAG 1113 ++ + I I+ LE+ GA + AD++D M+ V+ +AEA G I GV+H AGV Sbjct: 1058 QLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFGHINGVIHAAGVLRVKS 1117 Query: 1114 V---IQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFGQVGYN 1170 +++ ++ +E LPKV G LVLD L N LDF L SS+ + G G V Y+ Sbjct: 1118 AQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFCYLVSSLSPILGG--LGFVAYS 1175 Query: 1171 AANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFEAEAIT 1230 AAN +LD+F +INW DW G ++K N EA +T Sbjct: 1176 AANLYLDSFSDKVSNTSNNRWISINWGDWQYTG--------TEQVNKIFNAQSIEALEMT 1227 Query: 1231 TEQGVNVFRYIME-NQMNRVIVSALDLPALMEESNNISVEVILEQXXXXXXXXXXXXXXG 1289 +E+G F+ ++ + +N+VI+S+ DL ++ N++ + + Sbjct: 1228 SEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISELETQTKT-------- 1279 Query: 1290 SSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLVFKKLGVKLPL 1349 + +++ I IW ++ + +E+FF LG SL I I + +L + + Sbjct: 1280 GDKFRNQDEVEEIIIGIWKEFYSVDTVNENENFFDLGATSLHIIQIHERLINRLEKHISI 1339 Query: 1350 PAFFHKP 1356 F P Sbjct: 1340 GVMFEYP 1346 Score = 540 bits (1392), Expect = e-151, Method: Compositional matrix adjust. Identities = 283/644 (43%), Positives = 389/644 (60%), Gaps = 24/644 (3%) Query: 2 EIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGY 61 +IA+IG+ GRFPGA ++E+W+N+K+G S+Q F+++ELI +GV P YVKAKGY Sbjct: 1379 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1438 Query: 62 LEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPN 121 LE FDA FFDYTP +A LMDPQ++VFHEC W LIG+++GASPN Sbjct: 1439 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1498 Query: 122 HVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVHM 181 W+ L LS + G + S L DKD LS +I++K NLKGP+++I+T CSTSLVA+H Sbjct: 1499 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1558 Query: 182 AAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXXX 241 A Q+LL G CDIA+AGG+T+T PEK+GY YQEGM+ S DG CR F Sbjct: 1559 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1618 Query: 242 XVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPDS 301 VLK LQ+A++DGD I+AVIKG+A+NNDG +K G+TAPS GQ EVI+ A A V P+S Sbjct: 1619 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1678 Query: 302 IDYIECHGTGTPLGDPIELEALELGYNPERRHACALGSVKTNIGHLDSAAGIASFIKTVL 361 I YIE HGT T LGD IE++AL +N + + +GSVK N+GHL++A+G+A IKTV Sbjct: 1679 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1738 Query: 362 ALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGGTNAHII 421 A+K +LPPS++F PN + + FY+N RL EW N+PLRAG+S+FGIGGTNAHII Sbjct: 1739 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGGTNAHII 1798 Query: 422 VEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQVGRK 480 +E+AP S R +Q+L +SAK+ AL + +L + + P L D +YTLQ+GRK Sbjct: 1799 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSYTLQIGRK 1858 Query: 481 HFPIRE----------LALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXX 530 F R + L+N+ R +Q+ E+ V F+ + Sbjct: 1859 EFKHRRALVCSSTQEGIELLNQPEGRRVQYVNVKE-------EHPKVNFLFSGNGSQYVN 1911 Query: 531 XXXXXXXXXXXXXXPGARRF--LNQV--LGMMNRLVPDGAAVK--LEDLRKREYHPVLAF 584 F L V + M L P ++ E L++ E+ + F Sbjct: 1912 MGLELYEQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILF 1971 Query: 585 GSYYAVGKLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVR 628 YAV KL + WG+ PEA+IG +++AACL+ +LE+A++ Sbjct: 1972 AFEYAVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALK 2015 Score = 347 bits (889), Expect = 9e-93, Method: Compositional matrix adjust. Identities = 241/864 (27%), Positives = 411/864 (47%), Gaps = 50/864 (5%) Query: 684 NTYSLMAAVGTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNR 743 + Y L + + MW+ G + W + Y+ E+R R+ LP Y+F++ + + ++L LN Sbjct: 2211 DMYFLFSHITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLN- 2269 Query: 744 PPSGKGGTPADRDDIRKWFYIPAWESAAL--PNYEGRMLSRDAAWFIFCDPGGLG-EALG 800 K + ++I +WFY P W+S+ L PN++ + W +F D GLG E + Sbjct: 2270 ---SKQSKISKNNNISEWFYTPQWKSSTLFEPNHD-----VNETWIVFVDQEGLGNELVK 2321 Query: 801 DLLRQQQIRCIMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSLDAV---PDHICYLWTV 857 DLL + Q R + VE + + D + +NP + +L + + P I ++W + Sbjct: 2322 DLLNKGQ-RVVTVEPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGI 2380 Query: 858 TSPMEPELANIE---TGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLC 914 T+ E A+IE Q L + + L Q LG + + ++I++NG+ + +E L Sbjct: 2381 TN--EERQASIEYVNCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELI 2438 Query: 915 PMKGLLLGASKIIPYEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQFEFPNKQVAYR 974 P K +LG S ++P EY + VD L + R Q++ E +K +AYR Sbjct: 2439 PEKSTVLGTSLVVPQEYSYLSCSSVDVVLPLNKEWKNR-LINQLVEECLSNTNDKMIAYR 2497 Query: 975 GKSRWIEAVQKPLLLASPGKVSL-FRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVG 1033 G R+++ + PL L P K L R N V +IT A LVL+ Sbjct: 2498 GNKRFVQTYE-PLQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTLQANLVLLT 2556 Query: 1034 RSAFPPKSEWDQWMNRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAE 1093 R+ P + EWD M+ ++ + IR + +E G+ + V +AD++D S + + + +AE Sbjct: 2557 RTGLPNRDEWD--MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAE 2614 Query: 1094 ARLGPITGVLHTAGV--ADYAGVIQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVL 1151 + G I GV+H AG+ +IQ + +E K+ G L L+ RN+ LDF VL Sbjct: 2615 QKFGKINGVIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVL 2674 Query: 1152 FSSIGNYIYGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEK 1211 SSI + G G V Y A+N ++D F Y + + ++NW+DW K M+ Sbjct: 2675 MSSISAVLGG--LGYVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWKYWEDEEKDMQI 2732 Query: 1212 NRSLHKAVNDLQFEAEAITTEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEVI 1271 S+H+ ++T E+GV F + + V++ + P ++ I V+ Sbjct: 2733 GASVHEL---------SMTPEEGVQAFNIALSWKQGEVLIHS---PGELQA--RIDQWVL 2778 Query: 1272 LEQXXXXXXXXXXXXXXGSS-SLLTE-----AGLQQQIADIWSTVLGIEAIGIDEDFFAL 1325 L S LLTE ++++++ IW + + +G+ +D L Sbjct: 2779 LNSFNDEKEEELDSTLYHSRPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLEL 2838 Query: 1326 GGDSLKAITIVSLVFKKLGVKLPLPAFFHKPXXXXXXXXXXXXXXXDYARIKRAPQKEGY 1385 GGDSLKAITIVS + K+ V++P+ F ++ I A K Y Sbjct: 2839 GGDSLKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHY 2898 Query: 1386 PLTPGQKRLYFLSQMEQENKQYNNIIALQVNGPLDFGKLEACLKQLIRRHESLRTCFRRI 1445 L+ QKR Y L ++ E+ YN+ + +NG L+ +LE QLI+RHE RT Sbjct: 2899 QLSSAQKRFYVLHRLYPESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMK 2958 Query: 1446 GGEWVQWIEEEVQLALDVVDIKGTVNDKHIEAWIQAFDLAAAPLWKIGVFKEGEHRHLIV 1505 + VQ I + + ++ + ++ I +I+ F+ AP +++G+ + E +H+++ Sbjct: 2959 NDKPVQIIHDHADFHITQIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILI 3018 Query: 1506 FNIHHIITDGTSNAILIDEFTTLY 1529 ++HHI+TDG S I + + LY Sbjct: 3019 IDLHHIVTDGVSYDIFVRDLFALY 3042 >C3I386.1 C3I386_BACTU Polyketide synthase type I Length = 3338 Score = 720 bits (1859), Expect = 0.0, Method: Compositional matrix adjust. Identities = 450/1387 (32%), Positives = 710/1387 (51%), Gaps = 85/1387 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 LEIA+IG+AG+FPGA I+++WDNLKNGV S+ TF+E ELI GV + +VKAKG Sbjct: 13 LEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAKG 72 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 YLE FD FF YTP EA++MDPQ+++ E W + LIGL+ GAS Sbjct: 73 YLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAST 132 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVH 180 N W L V+ A L KD +S ++KL LKGP+ ++YTACSTSL+++H Sbjct: 133 NFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSIH 192 Query: 181 MAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXX 240 +A +SLL GEC IA AGGV++T P+K+GY+Y EGM SPDGK R F Sbjct: 193 LACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGVG 252 Query: 241 XXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPD 300 +LKRL+DA+ DGD IY VIKGSA NNDG +K G+TAPS GQAEVI+ A AEV P Sbjct: 253 MVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDPS 312 Query: 301 SIDYIECHGTGTPLGDPIELEALELGY-NPERRHACALGSVKTNIGHLDSAAGIASFIKT 359 +I YIE HGT TPLGD IE+EAL+ + + +++ CA+GSVK+N+GHLD+AAG+ IKT Sbjct: 313 TISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIKT 372 Query: 360 VLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPS-KNEPLRAGISAFGIGGTNA 418 VL++KH LPP+L+ + PN + I+ FYIN L W S N+ LRAG+SAFG GGTN Sbjct: 373 VLSMKHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSDDNDLLRAGVSAFGYGGTNV 432 Query: 419 HIIVEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQV 477 HI++E+AP + +++ RE +L+ +SA++ AL ++ +Y ++ L D+AYTLQ Sbjct: 433 HIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELADVAYTLQT 492 Query: 478 GRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 GR+ FP R A++ + + +T EN +IFV+P Sbjct: 493 GRRPFPYRR-AVLCKDIDSAIDNLKTVKDFHVKTQENPDLIFVLPSEYSSIIENVKELYQ 551 Query: 538 XXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKRE---YHPVLAFGSYYAVGKLF 594 R M + + G A+K + + + F ++ + Sbjct: 552 KEPLFLQVFER-------NMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSIIDVL 604 Query: 595 IEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVRSFLLSLDECGM-----ERPEAGRRSS 649 IE + P VIG G + ++ + L E+ + + + E E+ E + Sbjct: 605 IECDVRPSNVIGTGLAGMVSDIYNKSLKPEDVLNQLVENYTELQTEWTHGEKVELLTQVK 664 Query: 650 RREEIWLVLGAGNEAQPFLDKQSSKPQIIALEKLNTYSLMAAVGTMWLYGQDIKWRELYQ 709 + +++ G L+ + + QII L+ +G W G +I W +LY+ Sbjct: 665 DVDPNSMIVHIGE----LLNSEINNNQIILRN-----DLLEVLGQAWELGVEINWSKLYE 715 Query: 710 HEQRNRLSLPTYAFDRQEFPVDP-ELFNLNHLLNRPPSGKGGTPADRDDIRKWFYIPAWE 768 E R R++LPTY F+++ + +DP E N+ + + + R +I +WFY P W Sbjct: 716 EEYRFRIALPTYPFEKKRYWIDPAEQQNITN-------SEETSIKKRSNIAEWFYTPGWM 768 Query: 769 SAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRCIMVEHAEHYQQITADHYR 828 + + +W +F D +G AL + L + R I V Y++I+ + + Sbjct: 769 EKEIVDVTKE---STKSWLLFLDNEHIGLALKEKLERDGHRVITVGVGPSYKKISLNEFT 825 Query: 829 VNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELANIETGQQLFLHHILRLVQF 885 + P E+ +L++ L + +P+ I +LW V + + + ++TG + ++ L + Sbjct: 826 ICPTEQEDYYQLFNELQKQECLPEEIIHLWNVDNK-DLGIETLDTG----FYSLISLAKT 880 Query: 886 LGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIPYEYPNIKVCHVDFPLAE 945 + +++ +++N + + +E + K LL K+ P EYPNI+ VDF L++ Sbjct: 881 ISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSD 940 Query: 946 GDPARQREQARQMLREFQFEFPNKQVAYRGKSRWI--------EAVQKPLLLAS---PGK 994 + A + E Q + + +A R +R+I E V + L++ K Sbjct: 941 NEEAL----ISNLYSEIQTDIIDTVIAIRNNTRYIRIYEPIPDEKVSEMLVINENELASK 996 Query: 995 VSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWM-NRPDDA 1053 + R+ V +IT A+L+LV R+A P + EW+Q + ++ ++ Sbjct: 997 IPNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPDREEWNQILQSQIENE 1056 Query: 1054 EVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAGVADYAG 1113 ++ + I I+ LE+ GA + AD++D M+ V+ +AEA G I GV+H AGV Sbjct: 1057 QLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFGHINGVIHAAGVLRVKS 1116 Query: 1114 V---IQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFGQVGYN 1170 +++ ++ +E LPKV G LVLD L N LDF L SS+ + G G V Y+ Sbjct: 1117 AQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFCYLVSSLSPILGG--LGFVAYS 1174 Query: 1171 AANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFEAEAIT 1230 AAN +LD+F +INW DW G + ++K N EA +T Sbjct: 1175 AANLYLDSFSDKVSNTSNNRWTSINWGDWQYTGA--------QQVNKIFNAQSIEALEMT 1226 Query: 1231 TEQGVNVFRYIME-NQMNRVIVSALDLPALMEESNNISVEVILEQXXXXXXXXXXXXXXG 1289 +E+G F+ ++ + +N+VI+S+ DL ++ N++ + + Sbjct: 1227 SEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISELETQTKT-------- 1278 Query: 1290 SSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLVFKKLGVKLPL 1349 + +++ I IW ++ + ++E+FF LG SL I I + +L ++ + Sbjct: 1279 GDKFRNQDEVEEIIIGIWKEFYSVDTVNVNENFFDLGATSLHIIQIHERLINRLEKQISI 1338 Query: 1350 PAFFHKP 1356 F P Sbjct: 1339 GVMFEYP 1345 Score = 536 bits (1380), Expect = e-149, Method: Compositional matrix adjust. Identities = 277/637 (43%), Positives = 387/637 (60%), Gaps = 10/637 (1%) Query: 2 EIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGY 61 +IA+IG+ GRFPGA ++E+W+N+K+G S+Q F+++ELI +GV P YVKAKGY Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1437 Query: 62 LEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPN 121 LE FDA FFDYTP +A LMDPQ++VFHEC W LIG+++GASPN Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 122 HVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVHM 181 W+ L LS + G + S L DKD LS +I++K NLKGP+++I+T CSTSLVA+H Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 182 AAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXXX 241 A+Q+LL G CDIA+AGG+T+T PEK+GY YQEGM+ S DG CR F Sbjct: 1558 ASQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 242 XVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPDS 301 VLK LQ+A++DGD I+AVIKG+A+NNDG +K G+TAPS GQ EVI+ A A V P+S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 302 IDYIECHGTGTPLGDPIELEALELGYNPERRHACALGSVKTNIGHLDSAAGIASFIKTVL 361 I YIE HGT T LGD IE++AL +N + + +GSVK N+GHL++A+G+A IKTV Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 362 ALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGGTNAHII 421 A+K +LPPS++F PN + + FY+N +L EW N+PLRAG+S+FGIGGTNAHII Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 422 VEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQVGRK 480 +E+AP S R +Q+L +SAK+ AL + +L + + P L D +YTLQ+GRK Sbjct: 1798 LEEAPKLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHLNLADASYTLQIGRK 1857 Query: 481 HFPIRELALVNRKSQRVLQFAETATMK---GTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 F R + + + + Q + + E+ + F+ + Sbjct: 1858 EFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKINFLFSGNGSQYVNMGLELYE 1917 Query: 538 XXXXXXXPGARRF--LNQV--LGMMNRLVPDGAAVK--LEDLRKREYHPVLAFGSYYAVG 591 F L V + M L P ++ E L++ E+ + F Y+V Sbjct: 1918 QEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILFAFEYSVA 1977 Query: 592 KLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVR 628 KL + WG+ PEA+IG +++AACL+ +LE+A + Sbjct: 1978 KLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDAFK 2014 Score = 347 bits (889), Expect = 7e-93, Method: Compositional matrix adjust. Identities = 248/910 (27%), Positives = 429/910 (47%), Gaps = 60/910 (6%) Query: 648 SSRREEIWLVLGAGNE----AQPFLDKQSSKPQI------IALEKLNTYSLMAAVGTMWL 697 +S +++ +G GN+ LD ++ +I + + + Y L + + MW+ Sbjct: 2164 NSDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSDMYFLFSHITRMWV 2223 Query: 698 YGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNRPPSGKGGTPADRDD 757 G + W + Y+ E+R R+ LP Y+F++ + + ++L LN K + ++ Sbjct: 2224 TGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLN----SKQSKISKNNN 2279 Query: 758 IRKWFYIPAWESAAL--PNYEGRMLSRDAAWFIFCDPGGLG-EALGDLLRQQQIRCIMVE 814 I +WFY P W+S+ L PN++ + W +F D GLG E + DLL + Q R + VE Sbjct: 2280 ISEWFYTPQWKSSTLFEPNHD-----VNETWIVFVDQEGLGNELVKDLLNKGQ-RVVTVE 2333 Query: 815 HAEHYQQITADHYRVNPLRSEEMDRLYHSLDAV---PDHICYLWTVTSPMEPELANIE-- 869 + + D + +NP + +L + + P I ++W +T+ E A+IE Sbjct: 2334 PGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITN--EERQASIEYV 2391 Query: 870 -TGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIP 928 Q L + + L Q LG + + ++I++NG+ + +E L P K +LG S ++P Sbjct: 2392 NCKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVP 2451 Query: 929 YEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQFEFPNKQVAYRGKSRWIEAVQKPLL 988 EY + VD L + R Q++ E +K +AYRG R+++ + PL Sbjct: 2452 QEYSYLSCSSVDVVLPLNKEWKNR-LINQLVEECLSNTNDKMIAYRGNKRFVQTFE-PLQ 2509 Query: 989 LASPGKVSL-FRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWM 1047 L P K L R N V +IT A LVL+ R+ P + EWD M Sbjct: 2510 LEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEWD--M 2567 Query: 1048 NRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAG 1107 + ++ + IR + +E G+ + V +AD++D S + + + +AE + G I GV+H AG Sbjct: 2568 HLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKINGVIHGAG 2627 Query: 1108 V--ADYAGVIQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFG 1165 + +IQ + +E K+ G L L+ RN+ LDF VL SSI + G G Sbjct: 2628 ILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVLGG--LG 2685 Query: 1166 QVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFE 1225 V Y A+N ++D F Y + + ++NW+DW K M+ S+H+ Sbjct: 2686 YVSYAASNIYMDVFAQYINRYSKLPWISVNWSDWKYWEDEEKDMQIGASVHEL------- 2738 Query: 1226 AEAITTEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEVILEQXXXXXXXXXXX 1285 ++T E+GV F + + V++ + P ++ I V+L Sbjct: 2739 --SMTPEEGVQAFNIALSWKQGEVLIHS---PGELQAR--IDQWVLLNSFNDEKEEELDS 2791 Query: 1286 XXXGSS-SLLTE-----AGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLV 1339 S LLTE ++++++ IW + + +G+ +D LGGDSLKAITIVS + Sbjct: 2792 TLYHSRPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKI 2851 Query: 1340 FKKLGVKLPLPAFFHKPXXXXXXXXXXXXXXXDYARIKRAPQKEGYPLTPGQKRLYFLSQ 1399 K+ V++P+ F ++ I A K Y L+ QKR Y L + Sbjct: 2852 HKEFNVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHYQLSSAQKRFYVLHR 2911 Query: 1400 MEQENKQYNNIIALQVNGPLDFGKLEACLKQLIRRHESLRTCFRRIGGEWVQWIEEEVQL 1459 + E+ YN+ + +NG L+ +LE QLI+RHE RT + VQ I + Sbjct: 2912 LYPESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADF 2971 Query: 1460 ALDVVDIKGTVNDKHIEAWIQAFDLAAAPLWKIGVFKEGEHRHLIVFNIHHIITDGTSNA 1519 + ++ + ++ I +I+ F+ AP +++G+ + E +H+++ ++HHI+TDG S Sbjct: 2972 HITQIEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYD 3031 Query: 1520 ILIDEFTTLY 1529 I + + LY Sbjct: 3032 IFVRDLFALY 3041 >C3FU99.1 C3FU99_BACTB Polyketide synthase type I Length = 3338 Score = 719 bits (1855), Expect = 0.0, Method: Compositional matrix adjust. Identities = 448/1387 (32%), Positives = 711/1387 (51%), Gaps = 85/1387 (6%) Query: 1 LEIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKG 60 LEIA+IG+AG+FPGA I+++WDNLKNGV S+ TF+E ELI GV + +VKAKG Sbjct: 13 LEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAKG 72 Query: 61 YLEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASP 120 YLE FD FF YTP EA++MDPQ+++ E W + LIGL+ GAS Sbjct: 73 YLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAST 132 Query: 121 NHVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVH 180 N W L V+ A L KD +S ++KL LKGP+ ++YTACSTSL+++H Sbjct: 133 NFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSIH 192 Query: 181 MAAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXX 240 +A +SLL GEC IA AGGV++T P+K+GY+Y EGM SPDGK R F Sbjct: 193 LACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGVG 252 Query: 241 XXVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPD 300 +LKRL+DA+ DGD IY VIKGSA NNDG +K G+TAPS GQAEVI+ A AEV P Sbjct: 253 MVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDPS 312 Query: 301 SIDYIECHGTGTPLGDPIELEALELGY-NPERRHACALGSVKTNIGHLDSAAGIASFIKT 359 +I Y+E HGT TPLGD IE+EAL+ + + +++ CA+GSVK+N+GHLD+AAG+ IKT Sbjct: 313 TISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIKT 372 Query: 360 VLALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPS-KNEPLRAGISAFGIGGTNA 418 VL+++H LPP+L+ + PN + I+ FYIN L W S N+ LRAG+SAFG GGTN Sbjct: 373 VLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSDDNDLLRAGVSAFGYGGTNV 432 Query: 419 HIIVEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQV 477 HI++E+AP + +++ RE +L+ +SA++ AL ++ +Y ++ L D+AYTLQ Sbjct: 433 HIVLEEAPKVKSSASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELADVAYTLQT 492 Query: 478 GRKHFPIRELALVNRKSQRVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 GR+ FP R A++ + +T EN ++FV+P Sbjct: 493 GRRPFPYRR-AVLCMDIDSAIDNLKTVKDFHVKTQENPDLVFVLP-----SEYSSIIENV 546 Query: 538 XXXXXXXPGARRFLNQVLGMMNRLVPDGAAVKLEDLRKRE---YHPVLAFGSYYAVGKLF 594 P + + M + + G A+K + + + F ++ + Sbjct: 547 KELYQKEPLFLKVFER--NMTDAQMYTGKALKEAFFKGTDDSLVEDLTFFVCLQSIIDVL 604 Query: 595 IEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVRSFLLSLDECGM-----ERPEAGRRSS 649 IE + P +IG G + ++ + L E+ + + + E E+ E + Sbjct: 605 IECDVRPSNIIGTGLAGMVSDIYNKSLKPEDVLNQLVENYTELQTEWTHGEKVELLTQVK 664 Query: 650 RREEIWLVLGAGNEAQPFLDKQSSKPQIIALEKLNTYSLMAAVGTMWLYGQDIKWRELYQ 709 + +++ G L+ + + QII L+ +G W G +I W +LY+ Sbjct: 665 DVDPNSVIVHIGE----LLNSEINNNQIILQN-----DLLEVLGQAWELGVEINWSKLYE 715 Query: 710 HEQRNRLSLPTYAFDRQEFPVDP-ELFNLNHLLNRPPSGKGGTPADRDDIRKWFYIPAWE 768 E R R++LPTY F+++ + +DP E N+ + + + R +I +WFY P W Sbjct: 716 EEYRLRIALPTYPFEKKRYWIDPAEQQNITN-------SEETSIKKRSNIAEWFYTPGWM 768 Query: 769 SAALPNYEGRMLSRDAAWFIFCDPGGLGEALGDLLRQQQIRCIMVEHAEHYQQITADHYR 828 + + +W +F D +G AL + L + R I V Y++I+ + + Sbjct: 769 EKEIVDVTKE---STKSWLLFLDNEHIGLALKEKLERDGHRVITVGVGPSYKKISLNEFT 825 Query: 829 VNPLRSEEMDRLYHSL---DAVPDHICYLWTVTSPMEPELANIETGQQLFLHHILRLVQF 885 + P E+ +L++ L + +P+ I +LW V + + + ++TG + ++ L + Sbjct: 826 ICPTEQEDYYQLFNELQKQECLPEEIVHLWNVDNK-DLGIETLDTG----FYSLISLAKT 880 Query: 886 LGTAAAAQEVHLQIVSNGLYSITQEEMLCPMKGLLLGASKIIPYEYPNIKVCHVDFPLAE 945 + +++ +++N + + +E + K LL K+ P EYPNI+ VDF L++ Sbjct: 881 ISKFNLLYPININVMTNNMQKVVGDESIIAEKSTLLAPIKVFPQEYPNIRCRSVDFMLSD 940 Query: 946 GDPARQREQARQMLREFQFEFPNKQVAYRGKSRWI--------EAVQKPLLL---ASPGK 994 + A + E Q + + +A R +R+I E V + L++ S K Sbjct: 941 NEEAL----ISNLYSEIQTDIIDTVIAIRDNTRYIRIYEPIPDEKVSEMLVINENESASK 996 Query: 995 VSLFRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVGRSAFPPKSEWDQWM-NRPDDA 1053 + R+ V +IT A+L+LV R+A P + EWDQ + ++ ++ Sbjct: 997 IQNIRSEGVYLITGGMGGVGLKLAEYLARTVKAKLILVSRTALPDREEWDQILQSQIENE 1056 Query: 1054 EVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAEARLGPITGVLHTAGVADYAG 1113 ++ + I I+ LE+ GA + AD++D M+ V+ +AEA G I GV+H AGV Sbjct: 1057 QLCQRINHIQKLESLGAKVMTAVADVADEEQMRNVIHQAEANFGHINGVIHAAGVLRVKS 1116 Query: 1114 V---IQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVLFSSIGNYIYGRKFGQVGYN 1170 +++ ++ +E LPKV G LVLD L N LDF L SS+ + G G V Y+ Sbjct: 1117 AQCPMEKISRIECEEQFLPKVHGVLVLDKLLSNYDLDFCYLVSSLSPILGG--LGFVAYS 1174 Query: 1171 AANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEKNRSLHKAVNDLQFEAEAIT 1230 AAN +LD+F +INW DW G + ++K N EA +T Sbjct: 1175 AANLYLDSFSDKVSNTSNNRWTSINWGDWQYTG--------TQQVNKIFNAQSIEALEMT 1226 Query: 1231 TEQGVNVFRYIME-NQMNRVIVSALDLPALMEESNNISVEVILEQXXXXXXXXXXXXXXG 1289 +E+G F+ ++ + +N+VI+S+ DL ++ N++ + + Sbjct: 1227 SEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQWINLNSRKRISELETQTKT-------- 1278 Query: 1290 SSSLLTEAGLQQQIADIWSTVLGIEAIGIDEDFFALGGDSLKAITIVSLVFKKLGVKLPL 1349 + +++ I IW ++ + ++E+FF LG SL I I + +L + + Sbjct: 1279 GDKFRNQDEVEEIIIGIWKEFYSVDTVHVNENFFDLGATSLHIIQIHERLINRLEKHISI 1338 Query: 1350 PAFFHKP 1356 F P Sbjct: 1339 GVMFEYP 1345 Score = 536 bits (1380), Expect = e-150, Method: Compositional matrix adjust. Identities = 281/642 (43%), Positives = 390/642 (60%), Gaps = 20/642 (3%) Query: 2 EIAVIGLAGRFPGAGTISEYWDNLKNGVHSVQTFSEQELIAAGVEPGLAAKAEYVKAKGY 61 +IA+IG+ GRFPGA ++E+W+N+K+G S+Q F+++ELI +GV P YVKAKGY Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1437 Query: 62 LEAGHCFDARFFDYTPLEAELMDPQMKVFHECIWXXXXXXXXXXXXXQQLIGLFAGASPN 121 LE FDA FFDYTP +A LMDPQ++VFHEC W LIG+++GASPN Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 122 HVWEGLMGLSGKSGVMGHWAASQLLDKDYLSLRIAHKLNLKGPALSIYTACSTSLVAVHM 181 W+ L LS + G + S L DKD LS +I++K NLKGP+++I+T CSTSLVA+H Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 182 AAQSLLNGECDIALAGGVTVTLPEKSGYEYQEGMILSPDGKCRAFXXXXXXXXXXXXXXX 241 A Q+LL G CDIA+AGG+T+T PEK+GY YQEGM+ S DG CR F Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 242 XVLKRLQDALDDGDQIYAVIKGSAVNNDGLQKTGFTAPSTIGQAEVIRTALKLAEVSPDS 301 VLK LQ+A++DGD I+AVIKG+A+NNDG +K G+TAPS GQ EVI+ A A V P+S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 302 IDYIECHGTGTPLGDPIELEALELGYNPERRHACALGSVKTNIGHLDSAAGIASFIKTVL 361 I YIE HGT T LGD IE++AL +N + + +GSVK N+GHL++A+G+A IKTV Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 362 ALKHNILPPSLHFQTPNPVLKVIEKGFYINDRLTEWPSKNEPLRAGISAFGIGGTNAHII 421 A+K +LPPS++F PN + + FY+N +L EW N+PLRAG+S+FGIGGTNAHII Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 422 VEQAPPPREASAGREWQLLPVSAKTPSALAEIKQDLERYSKTEPR-RLEDIAYTLQVGRK 480 +E+AP S R +Q+L +SAK+ AL + +L + + P L D +YTLQ+GRK Sbjct: 1798 LEEAPKLEVTSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGRK 1857 Query: 481 HFPIRELALVNRKSQ---RVLQFAETATMKGTAGLENAPVIFVIPDFTQRXXXXXXXXXX 537 F R ALV +Q +L E ++ E P I +F Sbjct: 1858 EFKHRR-ALVCSSTQEGIELLNQPEGRRVQYVNVKEEHPKI----NFLFSGNGSQYVNMG 1912 Query: 538 XXXXXXXPGARRFLNQVLGMMNR---------LVPDGAAVK--LEDLRKREYHPVLAFGS 586 R +++ ++ L P ++ E L++ E+ + F Sbjct: 1913 LELYEQEAIFREAMDECFAILQSFTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILFAF 1972 Query: 587 YYAVGKLFIEWGLHPEAVIGRGKSQWLAACLSGELSLEEAVR 628 Y+V KL + WG+ PEA+IG +++AACL+ +LE+A++ Sbjct: 1973 EYSVAKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALK 2014 Score = 337 bits (865), Expect = 4e-90, Method: Compositional matrix adjust. Identities = 241/864 (27%), Positives = 405/864 (46%), Gaps = 50/864 (5%) Query: 684 NTYSLMAAVGTMWLYGQDIKWRELYQHEQRNRLSLPTYAFDRQEFPVDPELFNLNHLLNR 743 + Y L + + MW+ G I W + Y+ E+R R+ LP Y+F++ + + ++L LN Sbjct: 2210 DMYFLFSHITRMWVTGISIDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLN- 2268 Query: 744 PPSGKGGTPADRDDIRKWFYIPAWESAAL--PNYEGRMLSRDAAWFIFCDPGGLG-EALG 800 K + ++I +WFY P W+S+ L PN++ + W +F D GLG E + Sbjct: 2269 ---SKQSKISKNNNISEWFYTPQWKSSTLFEPNHD-----VNETWIVFVDQEGLGNELVK 2320 Query: 801 DLLRQQQIRCIMVEHAEHYQQITADHYRVNPLRSEEMDRLYHSLDAV---PDHICYLWTV 857 DLL + Q R + VE + + + +NP + +L + + P I ++W + Sbjct: 2321 DLLNKGQ-RVVTVEPGFGFNKENNGRFIINPEERTDYVKLLDEVQEICGLPTRIVHMWGI 2379 Query: 858 TSPMEPELANIE---TGQQLFLHHILRLVQFLGTAAAAQEVHLQIVSNGLYSITQEEMLC 914 T E A+IE Q L + I L Q LG + + ++I++NG+ + +E L Sbjct: 2380 TD--EERQASIEYVNCKQNLGFYSIFYLTQALGDKNISDSISIRIITNGVQQVIGDEELI 2437 Query: 915 PMKGLLLGASKIIPYEYPNIKVCHVDFPLAEGDPARQREQARQMLREFQFEFPNKQVAYR 974 P K +LG S ++P EY + VD L + R Q++ E +K +AYR Sbjct: 2438 PEKSTVLGTSLVVPQEYSYLSCSSVDVVLPLNKEWKSR-LINQLVEECLSNTNDKMIAYR 2496 Query: 975 GKSRWIEAVQKPLLLASPGKVSL-FRNNLVCMITXXXXXXXXXXXXXXXTQYTARLVLVG 1033 G R+++ + L L P K L R N V +IT A LVL+ Sbjct: 2497 GNKRFVQTYEH-LQLEQPAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLT 2555 Query: 1034 RSAFPPKSEWDQWMNRPDDAEVARIIRTIRALEAAGAVIEVHSADISDFSAMQQVVARAE 1093 R+ P + EWD M+ ++ + IR + +E G+ + V +AD++D S + + + +AE Sbjct: 2556 RTGLPNRDEWD--MHLKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAE 2613 Query: 1094 ARLGPITGVLHTAGV--ADYAGVIQRRTQAMTDEVLLPKVKGTLVLDTLFRNRRLDFFVL 1151 + G I GV+H AG+ +IQ + +E K+ G L L+ RN+ LDF VL Sbjct: 2614 QKFGKINGVIHGAGILGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVL 2673 Query: 1152 FSSIGNYIYGRKFGQVGYNAANEFLDAFVHYRLQNREGFTATINWNDWAEAGMSVKAMEK 1211 SSI + G G V Y A+N ++D F Y + ++NW+DW K M+ Sbjct: 2674 MSSISAVLGG--LGYVSYAASNIYMDVFAQYINRYSNLPWISVNWSDWKYWEDEEKDMQI 2731 Query: 1212 NRSLHKAVNDLQFEAEAITTEQGVNVFRYIMENQMNRVIVSALDLPALMEESNNISVEVI 1271 S+H+ ++T E+GV F + + V++ + P ++ I V+ Sbjct: 2732 GASVHEL---------SMTPEEGVQAFNIALSWKQGEVLIHS---PGELQA--RIDQWVL 2777 Query: 1272 LEQXXXXXXXXXXXXXXGSS-SLLTE-----AGLQQQIADIWSTVLGIEAIGIDEDFFAL 1325 L S LLTE ++++++ IW + + +G +D L Sbjct: 2778 LNSFNDEKEEELDSTLYHSRPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGAHDDLLEL 2837 Query: 1326 GGDSLKAITIVSLVFKKLGVKLPLPAFFHKPXXXXXXXXXXXXXXXDYARIKRAPQKEGY 1385 GGDSLKAITIVS + K+ V++P+ F ++ I A K Y Sbjct: 2838 GGDSLKAITIVSKIHKEFNVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHY 2897 Query: 1386 PLTPGQKRLYFLSQMEQENKQYNNIIALQVNGPLDFGKLEACLKQLIRRHESLRTCFRRI 1445 L+ QKR Y L ++ E+ YN+ + +NG L+ +LE QLI+RHE RT Sbjct: 2898 QLSSAQKRFYVLHRLYPESTAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMK 2957 Query: 1446 GGEWVQWIEEEVQLALDVVDIKGTVNDKHIEAWIQAFDLAAAPLWKIGVFKEGEHRHLIV 1505 + VQ I + + ++ + ++ I +I F+ AP +++G+ + E +H+++ Sbjct: 2958 NDKPVQIIHDHADFHITQIEGFESEVEQIINEFICPFNFNNAPYFRVGLIRLEEQKHILI 3017 Query: 1506 FNIHHIITDGTSNAILIDEFTTLY 1529 ++HHI+TDG S I + + LY Sbjct: 3018 IDLHHIVTDGVSYDIFVRDLFALY 3041 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.410 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 8,863,733,185 Number of extensions: 361055426 Number of successful extensions: 890434 Number of sequences better than 1.0e-05: 11378 Number of HSP's gapped: 844459 Number of HSP's successfully gapped: 16638 Length of query: 1557 Length of database: 3,060,696,203 Length adjustment: 149 Effective length of query: 1408 Effective length of database: 1,656,964,968 Effective search space: 2333006674944 Effective search space used: 2333006674944 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 138 (57.8 bits)