BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0023.p (2551 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I5H3.1 B8I5H3_CLOCE Beta-ketoacyl synthase 840 0.0 B8I978.1 B8I978_CLOCE Beta-ketoacyl synthase 837 0.0 B8I5I1.1 B8I5I1_CLOCE Amino acid adenylation domain protein 804 0.0 B8I5I2.1 B8I5I2_CLOCE Beta-ketoacyl synthase 728 0.0 A7Z4Y6.1 A7Z4Y6_BACA2 BaeL 647 0.0 >B8I5H3.1 B8I5H3_CLOCE Beta-ketoacyl synthase Length = 1620 Score = 840 bits (2170), Expect = 0.0, Method: Compositional matrix adjust. Identities = 461/1239 (37%), Positives = 713/1239 (57%), Gaps = 41/1239 (3%) Query: 1296 QPAESDEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLAANQISPE 1355 Q E+DE AIIG A KFP +E+ E++W NL I P R G A Sbjct: 37 QHIENDEIAIIGMAGKFPGSENLEEYWENLMDSRLCIGKIPPDR-----GSFAVEITEGT 91 Query: 1356 GHAYCQGGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGGTILSGTR 1415 +Y + GY++EID+FD+AFF ISP+E + MDP QR+ LE ++A E +G GG L G+ Sbjct: 92 DSSYSKAGYIKEIDKFDAAFFRISPKEAKYMDPIQRVFLETAWEAIEDAGYGGDRLYGSN 151 Query: 1416 TGVYVGKDTTGRNEYNNRVDILDPLKVTSGSTGILASRIAYYLNLNGPCLVVDTACSSSL 1475 TGVY G D T + Y + DPL +T +GILASRI+Y LNLNGP LV+DTACSS L Sbjct: 152 TGVYTGNDHTWGSPYKYMIQDRDPLAITGSWSGILASRISYILNLNGPALVIDTACSSGL 211 Query: 1476 TAICLATQALKQGQIDIAIVAGVSLAYLPTQRNSL--IDSADEMIRPFDAGANGTMWGEG 1533 A+ A ALK G+ +AI G+ + Y P + N + ++S D IR FD A+GT+WGEG Sbjct: 212 VAVHEACNALKTGKCQMAIAGGIHIIYKPIENNEMGIVESNDSTIRAFDDKASGTVWGEG 271 Query: 1534 AGTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPNAEAQEKVLVAAWKAANIDP 1593 G +ILK + +A++D I+AVIKGS +NN+G SNGITAP AEAQE +L+ AWK A I+P Sbjct: 272 VGVVILKPLKKAMEDKDEIYAVIKGSAVNNDGASNGITAPKAEAQEDLLIKAWKEARINP 331 Query: 1594 ETISYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAGTVKANIGHLVGASGMASVI 1653 E ISYIE H TGT LGDPIE+KG++ AFR+FT K QFC G+VK N+GHLVGASG+AS+I Sbjct: 332 ENISYIETHGTGTVLGDPIEIKGLSRAFRKFTKKNQFCGIGSVKTNLGHLVGASGIASLI 391 Query: 1654 KMIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWSGSAAPRRCGISSFGFSGTN 1713 K ++A K +PP L F+ PN +I+F+++P+YVND+ W R CG+SSFGFSGTN Sbjct: 392 KTVLAINKKVIPPTLNFEYPNRYIDFSNAPVYVNDKTTFWEADQNIRLCGVSSFGFSGTN 451 Query: 1714 CHILLEEPPVFTNPQEAKQDWHILALSAKTAGSLSALIKRYFHMINGTVTLDLQNLCFTA 1773 CH++++E + A + LSAK+ S+ L++RY IN L+++C T Sbjct: 452 CHVVIQEVKKEIRAETASHRPMVFTLSAKSQFSMKELVQRYLKFINRPEVPSLKDICSTT 511 Query: 1774 NISRGHYEHRIVLLFRTENELRAKFKYLQEAGILQAADRDQRIYYKASRISYDQEGF-DG 1832 + RGHY +R ++ R +ELR K L+E ++ Q IY+ +I ++G + Sbjct: 512 AVGRGHYNYRAAIIVRGMDELREKLIQLREVIDIKQT-HVQNIYFGEHKIVSSKKGLNEA 570 Query: 1833 DGLLEQDKLKLNKLAESLIEEWSVEETLSAVDNLHKIARLYTDGADINWDRLYQGKQHRL 1892 + + E ++ ++++ A+ ++ + E V L ++ RLYT GAD++W++ Y+G R Sbjct: 571 NDITEHERREISQKADLKLKAFLQGE----VHELEELCRLYTIGADVDWNKFYEGTGGRT 626 Query: 1893 TELPAYAYEPVRHWIGGSA--RKGSSSPGK----YYQLQWLPDHREQPAGIK-PDEGAWL 1945 LP Y +E R+WI + + +P K Y+++W+P + + ++ + Sbjct: 627 VHLPPYPFERNRYWIDNEKGEKTKAVTPEKNKHNLYEIRWVPCTEAPKSSMNLTNKTVAI 686 Query: 1946 FVGGTGTKSQELLRVLRKQEIELIEVTPGARYHQLAANRYSI-GSGEEYSLLLKELSNRG 2004 F+ G + L L + I++I+V G Y + Y+I G +Y L +++ +R Sbjct: 687 FMDAEGI-GEGLASNLTDKGIDVIQVMLGESYEKKNELSYTISGCERDYYKLFEDMGDRR 745 Query: 2005 IKHVIHCLSLADEKIA-GIEDLHAAENRGVYNLHHLVTALLNGQYHQELNLFFVADHTFL 2063 I +IH ++ E+L + GVY+L ++V + + Q + + V+ +TF Sbjct: 746 ISKIIHLFGNRSKQYGDSPEELELSHITGVYSLFYMVKSFAKLKSGQSVEMVLVSRNTFS 805 Query: 2064 VNRHEPVLNPHHAVLFGMAKVIPQEYPQFKCRCIDIDSATAPATVWKEICSGKGDFQVAY 2123 V++ E NP +A LF + +VI EY +CR +DID+ T ++ E+ + A Sbjct: 806 VDKQEKKANPGNAALFALGRVISAEYENIRCRGVDIDTDTDANSLVSEVYGYNTSYLTAI 865 Query: 2124 RDNTRYLEHFGERRLEAAEAGGVSLKENGVYVVTGGLGGIGLAVAQYLSGKQRVHLCLLN 2183 RD RY++ F + G+ +K GVY++TGGLGGIGL +A++LS K ++ L+N Sbjct: 866 RDGKRYIQEFARLEMGGGSRKGIDIKSQGVYIITGGLGGIGLEIARHLSQKGAGNIALVN 925 Query: 2184 RRTLP------------PGPSQSQR---IRQIEANGSDVDLYSVDISAPNELQGVLQAIR 2228 R ++P QR I IEA+G+ V Y DIS +++ GV+ IR Sbjct: 926 RSSMPERHEWAEILKAGADTKLCQRINAINSIEADGTAVFSYPGDISVKDQMMGVINEIR 985 Query: 2229 TKYGQINGLFHCAGIAGEGLLINKGKPEIKRVLDAKVTGTWLLDQYTAQDHLDYFVLFSS 2288 K+ ING+ HCAG+AGEGL+ K + ++ +VL K+ GT++LD T +D +D+FV FSS Sbjct: 986 DKFNNINGIIHCAGLAGEGLISGKSQADLSKVLSPKIEGTFMLDNVTREDEIDFFVTFSS 1045 Query: 2289 VTSLLGGMGQADYTAANAYLDGFSDYRQANNRRSVTINWPAWKEVGMTLKYDIQEGRSPF 2348 V S+L GQ DY AANA++D F+ +R +R+V+I+WPAWK+ GM +Y + +S F Sbjct: 1046 VMSILNVPGQGDYAAANAFMDSFAQWRSTQGKRTVSISWPAWKDTGMAAEYKADKNKSLF 1105 Query: 2349 LGLTEEQGISILDAVLQRKLSRIIAGEINERYFQNGDPSLP-FAVPPQMISRGTGAFNPQ 2407 ++ EQ +S + +L+ + + +IAGE++ + F + + + + Sbjct: 1106 KPISVEQALSDFELILESESTHVIAGELDFEMLSGISEDIQLFKLEKDIAAELESTVSSN 1165 Query: 2408 EKVIADEPILPI--LKGRYDHSYNSYEISLAAMWQKVLGVAEVNVHLPFQETGGNSILAT 2465 + E LP LKG +Y E + +W +L + E+++H F + GGNS+L+ Sbjct: 1166 SLISVKESPLPTVKLKGGVSGNYTKLEKLIGNIWGAILEIGELSIHDDFYDLGGNSLLSI 1225 Query: 2466 SLVKEIDGVYPGCVNIATLFAYPSIAKMAEYLKQKQSEN 2504 ++ ++ ++I LF + SI +A ++ +K E+ Sbjct: 1226 NMASKLKEQLNVEIDINNLFEHFSIVDLAMFISEKYPES 1264 Score = 715 bits (1845), Expect = 0.0, Method: Compositional matrix adjust. Identities = 433/1268 (34%), Positives = 679/1268 (53%), Gaps = 42/1268 (3%) Query: 9 IYELVASKKLTAKEATEYITYLQNGNEH-RSEEIAVVGISGRFPKADRVEQFWDNLCSGR 67 IY+LVA KKL +++ ++ LQ +H ++EIA++G++G+FP ++ +E++W+NL R Sbjct: 11 IYKLVADKKLDPQDSVVLLSELQKNKQHIENDEIAIIGMAGKFPGSENLEEYWENLMDSR 70 Query: 68 DCLDTFPEDRLHDGQALAPERHLAGGSLKQGGYLDEISFFDAEMFRISPKEALSMEPYQR 127 C+ P DR G S + GY+ EI FDA FRISPKEA M+P QR Sbjct: 71 LCIGKIPPDR---GSFAVEITEGTDSSYSKAGYIKEIDKFDAAFFRISPKEAKYMDPIQR 127 Query: 128 IMLEVAYDTLVNAGYETQDILGSKTGVFIGRDHVTGIEYRNYAAP-DIFRLTGGWPGILA 186 + LE A++ + +AGY + GS TGV+ G DH G Y+ D +TG W GILA Sbjct: 128 VFLETAWEAIEDAGYGGDRLYGSNTGVYTGNDHTWGSPYKYMIQDRDPLAITGSWSGILA 187 Query: 187 SRISYVYNLKGPSVVFDTSCSSGLVGLHFACESLRRNECDMAFVGGISGLFYFPPVKEDG 246 SRISY+ NL GP++V DT+CSSGLV +H AC +L+ +C MA GGI + P+ E+ Sbjct: 188 SRISYILNLNGPALVIDTACSSGLVAVHEACNALKTGKCQMAIAGGIH--IIYKPI-ENN 244 Query: 247 SLDQVESAEEKIRAFDKAAEGTVWGEGCGGLLLKPLSKAVADKDVIYAVIKGSGINNNGL 306 + VES + IRAFD A GTVWGEG G ++LKPL KA+ DKD IYAVIKGS +NN+G Sbjct: 245 EMGIVESNDSTIRAFDDKASGTVWGEGVGVVILKPLKKAMEDKDEIYAVIKGSAVNNDGA 304 Query: 307 SKGITAPNGEAQEELLKKVWKQAQINPETIRYIETHGTGTILGDTIELNSIINAFQAFTS 366 S GITAP EAQE+LL K WK+A+INPE I YIETHGTGT+LGD IE+ + AF+ FT Sbjct: 305 SNGITAPKAEAQEDLLIKAWKEARINPENISYIETHGTGTVLGDPIEIKGLSRAFRKFTK 364 Query: 367 KKQFCGVGSVKTNIGHLVGASGIVSLIKAVLMLKHGEIPASLHFQTPSPYINLADSALFI 426 K QFCG+GSVKTN+GHLVGASGI SLIK VL + IP +L+F+ P+ YI+ +++ +++ Sbjct: 365 KNQFCGIGSVKTNLGHLVGASGIASLIKTVLAINKKVIPPTLNFEYPNRYIDFSNAPVYV 424 Query: 427 NDQRSKLEKGNHPVRIGINSFGFSGTNCHVLLEEPPVPVYDNNAENNVFLLTLSARSSQK 486 ND+ + E + G++SFGFSGTNCHV+++E + A + + TLSA+S Sbjct: 425 NDKTTFWEADQNIRLCGVSSFGFSGTNCHVVIQEVKKEIRAETASHRPMVFTLSAKSQFS 484 Query: 487 LVEAAQSLQRFLLTNRSVNLADMCCTASQFRNHFANRLAITFSSYEDLLAKLKIIRETKE 546 + E Q +F+ +L D+C T + R H+ R AI ++L KL +RE Sbjct: 485 MKELVQRYLKFINRPEVPSLKDICSTTAVGRGHYNYRAAIIVRGMDELREKLIQLREV-- 542 Query: 547 LSLWSSH-PGISFQLHEVVADTKSQIEAWEIREGEKIALDKTANEAIRELLQKKAGSEML 605 + + +H I F H++V+ K EA +I E E+ + + A+ ++ LQ G Sbjct: 543 IDIKQTHVQNIYFGEHKIVSSKKGLNEANDITEHERREISQKADLKLKAFLQ---GEVHE 599 Query: 606 WEQAARFYIKGASMDWRPLYPGC--RKLAMPGNVLERTKYWPAEAKRGEVYQ-------D 656 E+ R Y GA +DW Y G R + +P ER +YW + ++GE + Sbjct: 600 LEELCRLYTIGADVDWNKFYEGTGGRTVHLPPYPFERNRYW-IDNEKGEKTKAVTPEKNK 658 Query: 657 ELYYTTEWVEESRLPAGSGAARETVLLIVHEADTALWEAQLPGKLRRK--RCILVEIGRP 714 Y WV + P S + I +A+ + E L L K I V +G Sbjct: 659 HNLYEIRWVPCTEAPKSSMNLTNKTVAIFMDAE-GIGEG-LASNLTDKGIDVIQVMLGES 716 Query: 715 YRKINAEHYHVSNSVEDFSALCGELDISALEQILYAAPSR-EGLPDSLKEFKESFNQTVM 773 Y K N Y +S D+ L ++ + +I++ +R + DS +E + S V Sbjct: 717 YEKKNELSYTISGCERDYYKLFEDMGDRRISKIIHLFGNRSKQYGDSPEELELSHITGVY 776 Query: 774 NLLYLVKALQAANTMNKDLDIALITRNAHVLQPMDTGSDPFAHTLYGIGKSILQENRSFH 833 +L Y+VK+ + + +++ L++RN + + ++P L+ +G+ I E + Sbjct: 777 SLFYMVKSFAKLKS-GQSVEMVLVSRNTFSVDKQEKKANPGNAALFALGRVISAEYENIR 835 Query: 834 VRHIDISNEPADLEALPAELEVPSAQYSVALRHGRRYVEVIKRXXXXXXXXXXXXXXXXX 893 R +DI + D +L +E+ + Y A+R G+RY++ R Sbjct: 836 CRGVDIDTD-TDANSLVSEVYGYNTSYLTAIRDGKRYIQEFARLEMGGGSRKGIDIKSQG 894 Query: 894 TFXXXXXXXXXXXEVCKYLSQKNRVKLIVLGRTAIPDRESWQSIIMDNEDKQLLKKINGI 953 + E+ ++LSQK + ++ R+++P+R W I+ D +L ++IN I Sbjct: 895 VYIITGGLGGIGLEIARHLSQKGAGNIALVNRSSMPERHEWAEILKAGADTKLCQRINAI 954 Query: 954 LAIEALGFTLDYHCVDICDEAQLRRTVEQIRQDHGSINGVFHCAGV-GVGDIEDFGMSGQ 1012 +IEA G + + DI + Q+ + +IR +ING+ HCAG+ G G I G S Sbjct: 955 NSIEADGTAVFSYPGDISVKDQMMGVINEIRDKFNNINGIIHCAGLAGEGLIS--GKSQA 1012 Query: 1013 EFEQRHAVKTYGSWLVYNLTQEFNTGFTLLFSSAVSITGGRGSLAYTAGNAFVDGLAETI 1072 + + + K G++++ N+T+E F + FSS +SI G Y A NAF+D A+ Sbjct: 1013 DLSKVLSPKIEGTFMLDNVTREDEIDFFVTFSSVMSILNVPGQGDYAAANAFMDSFAQWR 1072 Query: 1073 RLQGKNVMAINWSTWEATASRLSLQADKH--FFEFLSTHQALQALDLIIRRGMFRTIVGK 1130 QGK ++I+W W+ T +ADK+ F+ +S QAL +LI+ I G+ Sbjct: 1073 STQGKRTVSISWPAWKDTGMAAEYKADKNKSLFKPISVEQALSDFELILESESTHVIAGE 1132 Query: 1131 LNVQNKLLELENLWPFRLAGEIKQALFPKTRQ------EERPVRQTSVTVKEPEGYTATH 1184 L+ + E++ F+L +I L +E P+ + YT Sbjct: 1133 LDFEMLSGISEDIQLFKLEKDIAAELESTVSSNSLISVKESPLPTVKLKGGVSGNYTKLE 1192 Query: 1185 RELAQVWADILGLTTISVFDSFHQLGGDSIHAAHLHKQWNERHPGTLDVTDIYRYPTIHE 1244 + + +W IL + +S+ D F+ LGG+S+ + ++ + E+ +D+ +++ + +I + Sbjct: 1193 KLIGNIWGAILEIGELSIHDDFYDLGGNSLLSINMASKLKEQLNVEIDINNLFEHFSIVD 1252 Query: 1245 MAGYLDSQ 1252 +A ++ + Sbjct: 1253 LAMFISEK 1260 >B8I978.1 B8I978_CLOCE Beta-ketoacyl synthase Length = 1272 Score = 837 bits (2162), Expect = 0.0, Method: Compositional matrix adjust. Identities = 475/1276 (37%), Positives = 725/1276 (56%), Gaps = 61/1276 (4%) Query: 1301 DEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLAANQISPEGHAYC 1360 ++ A+IG + P A+D E FW NL G I FP SRR+DT+ YL S + + Y Sbjct: 26 EDIAVIGMYARLPQADDIEGFWDNLKNGRDCITKFPASRRRDTESYLHYKG-STKRNRYS 84 Query: 1361 QGGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGGTILSGTRTGVYV 1420 G YLE+ID+FD++FF+I+P+E LM P QR+ LE ++A E +G GG L G++TGVY+ Sbjct: 85 TGAYLEDIDKFDNSFFNITPKEASLMSPNQRIFLEATWKAIEDAGYGGKKLVGSKTGVYI 144 Query: 1421 GKDTTGRNEYNNRVDILDPLKVTSGSTG----ILASRIAYYLNLNGPCLVVDTACSSSLT 1476 G + +Y ++ DP V+ TG ++ SRI+Y L+L GP + +DTACSS+L Sbjct: 145 GFEADAPFDYTRYIEAFDPKSVSVAVTGNLTSVIPSRISYLLDLKGPSISIDTACSSALV 204 Query: 1477 AICLATQALKQGQIDIAIVAGVSLAYLPT--QRNSLIDSADEMIRPFDAGANGTMWGEGA 1534 A+ +A + +K ++AIV + L ++P Q N I+++D + FD ++GT GEG Sbjct: 205 AVHMACKGIKNKDCEMAIVGSIRLNFMPMEGQLNFGINASDGRAKTFDDSSDGTGSGEGV 264 Query: 1535 GTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPNAEAQEKVLVAAWKAANIDPE 1594 T +LK +S A++D IHAVIKGS +N +G S G++APN AQE V+V+AWK A IDPE Sbjct: 265 ITYLLKPLSRALKDKDNIHAVIKGSAINQDGRSIGLSAPNVLAQEDVIVSAWKDAGIDPE 324 Query: 1595 TISYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAGTVKANIGHLVGASGMASVIK 1654 T+SYIEAH TGTKLGDPIEV GI+ AFRR+T+K+QFC+ G+VK NIGHL A+G+A ++K Sbjct: 325 TVSYIEAHGTGTKLGDPIEVDGISRAFRRYTSKKQFCSIGSVKTNIGHLDNAAGVAGMLK 384 Query: 1655 MIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWSGSAAPRRCGISSFGFSGTNC 1714 +++ K+KQLP L ++ PN I F DSP+YVND+L W PRRCG+SSFGFSGTNC Sbjct: 385 AVLSLKNKQLPASLHYKVPNRRINFKDSPVYVNDKLTPWETHGFPRRCGVSSFGFSGTNC 444 Query: 1715 HILLEEPPVFTNPQEAKQDWHILALSAKTAGSLSALIKRYFHMINGTVTLDLQNLCFTAN 1774 HI+LEE P N + +L LSAKT +L L+KRY I +D+ N+C+T N Sbjct: 445 HIILEEAPSVVNKSIDRPCLEVLTLSAKTNDALKELVKRYRLYIQKNEDVDIGNMCYTQN 504 Query: 1775 ISRGHYEHRIVLLFRTENELRAKFKYLQEAGILQAADRDQRIYYKASRISYDQEGFDGDG 1834 R H+++RI ++ R EL+ K L +++ IY+ + Q+G +G Sbjct: 505 TGRWHFDYRIAVIARNTIELKNKLDKLVSIDFEDINEKE--IYFGIQLDNIKQKG--QNG 560 Query: 1835 LLEQDKLKLNKLAESLIEEWSVEETLSAVDNLHKIARLYTDGADINWDRLYQGKQHRLTE 1894 L E +L+ A+ +EE+ + E + D L+ I + Y +GA+I+WD LY+G+ Sbjct: 561 LFESKIKELSCEADKKLEEFILSEK-TEEDVLYDICKRYVEGANIDWDILYKGEDRTRIS 619 Query: 1895 LPAYAYEPVRHWIGGSARKGSSSPGKYYQLQWLPDHREQPAGIKPDEGAWLFVGGTGTKS 1954 LP Y + R WI +A +G + +Y W ++ + IK G+ L + K+ Sbjct: 620 LPTYPFRRTRCWI--NAEEGLEND-LFYVTAWESKILKKSSTIK---GSVLLFRDSIGKA 673 Query: 1955 QELLRVLRKQEIELIEVTPGARYHQLAANRYSI-GSGEEYSLLLKELSNRGIKHVIHCLS 2013 ++L+ +LR ++ +IEV G++Y ++ +RY I S + LL ++ + +++VIH S Sbjct: 674 EKLVAILRGMQVNVIEVDIGSKYKKINNSRYQISASAKAIQSLLNDIDIKDLRYVIHMAS 733 Query: 2014 LADEKIAGIEDLHAAENRGVYNLHHLVTALLNGQYHQELNLFFVADHTFLVNRHEPVLNP 2073 +++ I L G+Y+L+HL+ LN+ V+++ + E L P Sbjct: 734 ISESSTEDISILKQKLQNGIYSLYHLLQGTAKLGLKDRLNIVVVSEYVNKICGEENTLKP 793 Query: 2074 HHAVLFGMAKVIPQEYPQFKCRCIDIDSATAPATVWKEICSGKGDFQVAYRDNTRYLEHF 2133 +A +FGM K EYP RCIDID T + + EI + +F YR+ RY+E Sbjct: 794 ENAAMFGMGKSAFWEYPNISIRCIDIDRDTDISVIVPEISAEGVEFCTGYRNGNRYVEII 853 Query: 2134 GERRLEAAEAGGVSLKENGVYVVTGGLGGIGLAVAQYLSGK-QRVHLCLLNRRTLP---- 2188 + +E + +KE GVYV+TGG GG+G+ A+ L + +R L +NR LP Sbjct: 854 KQASIENKL---LDIKEEGVYVITGGAGGLGIEFAKRLVLRNRRAKLAFINRSKLPERND 910 Query: 2189 ------PGPSQS-----QRIRQIEANGSDVDLYSVDISAPNELQGVLQAIRTKYGQINGL 2237 G + I+ +EA G+++ L S D+S ++ V+ ++ +YG ING+ Sbjct: 911 WDAILASGSDEKMCRLLNNIKDMEARGAEITLLSADVSEFEGMKVVISELKRRYGNINGI 970 Query: 2238 FHCAGIAGEGLLINKGKPEIKRVLDAKVTGTWLLDQYTAQDHLDYFVLFSSVTSLLGGMG 2297 H AGI+ ++ + +++ VL K+ G W+LD+ T +++LD+FV+ SS +L+GG+G Sbjct: 971 IHSAGISKR----DETEEDLRAVLSPKIEGAWILDRLTQEENLDFFVMCSSAITLIGGLG 1026 Query: 2298 QADYTAANAYLDGFSDYRQANNRRSVTINWPAWKEVGMTLKYDIQEGRSPFLGLTEEQGI 2357 YTAANAYLD FS R + +R++ INW AW+ G+ I E + F L E + Sbjct: 1027 GGGYTAANAYLDSFSAQRSSQGKRTLAINWAAWENTGLAEGMTINEDKELFRVLLPENAL 1086 Query: 2358 SILDAVLQRKLSRIIAGEIN-ERYFQNGDPSLPFAVPPQMISRGTGAFNPQEKVIADEPI 2416 + L L R+I GE+N N LPF + + N EK + +E Sbjct: 1087 DAFENALNSNLDRVIIGELNLSSTILNLGEYLPFRLSDNLKK------NTIEKTVQEEEQ 1140 Query: 2417 LP--ILKGRYDHSYNSYEISLAAMWQKVLGVAEVNVHLPFQETGGNSILATSLVKEIDGV 2474 L LKG+ + Y E+ +A +W +VLG E NV+ F GG+SI+ T + ++ Sbjct: 1141 LKDIKLKGKEEQDYTKTEVLIAKIWGEVLGFEEFNVNDNFFTLGGDSIMITRVETLLEKH 1200 Query: 2475 YPGCVNIATLFAYPSIAKMAEYLKQKQSENESLQEADPKTAKRMELSDKLSGFVE----G 2530 YPG + I+ LFAYP+I+K+++YL Q S +EAD EL D + E G Sbjct: 1201 YPGRITISELFAYPTISKLSQYLSSSQI---SGKEAD---TGETELRDSIFKLFEDIRAG 1254 Query: 2531 KVPIENILQYLDNNEL 2546 I + ++Y D+ E+ Sbjct: 1255 SRNISSAIKYYDSLEV 1270 Score = 714 bits (1844), Expect = 0.0, Method: Compositional matrix adjust. Identities = 420/1239 (33%), Positives = 681/1239 (54%), Gaps = 49/1239 (3%) Query: 39 EEIAVVGISGRFPKADRVEQFWDNLCSGRDCLDTFPEDRLHDGQALAPERHLAGGSLKQ- 97 E+IAV+G+ R P+AD +E FWDNL +GRDC+ FP R D ++ H G + + Sbjct: 26 EDIAVIGMYARLPQADDIEGFWDNLKNGRDCITKFPASRRRDTESYL---HYKGSTKRNR 82 Query: 98 ---GGYLDEISFFDAEMFRISPKEALSMEPYQRIMLEVAYDTLVNAGYETQDILGSKTGV 154 G YL++I FD F I+PKEA M P QRI LE + + +AGY + ++GSKTGV Sbjct: 83 YSTGAYLEDIDKFDNSFFNITPKEASLMSPNQRIFLEATWKAIEDAGYGGKKLVGSKTGV 142 Query: 155 FIGRDHVTGIEYRNY-AAPD----IFRLTGGWPGILASRISYVYNLKGPSVVFDTSCSSG 209 +IG + +Y Y A D +TG ++ SRISY+ +LKGPS+ DT+CSS Sbjct: 143 YIGFEADAPFDYTRYIEAFDPKSVSVAVTGNLTSVIPSRISYLLDLKGPSISIDTACSSA 202 Query: 210 LVGLHFACESLRRNECDMAFVGGISGLFYFPPVKEDGSLD-QVESAEEKIRAFDKAAEGT 268 LV +H AC+ ++ +C+MA VG I F P+ +G L+ + +++ + + FD +++GT Sbjct: 203 LVAVHMACKGIKNKDCEMAIVGSIR--LNFMPM--EGQLNFGINASDGRAKTFDDSSDGT 258 Query: 269 VWGEGCGGLLLKPLSKAVADKDVIYAVIKGSGINNNGLSKGITAPNGEAQEELLKKVWKQ 328 GEG LLKPLS+A+ DKD I+AVIKGS IN +G S G++APN AQE+++ WK Sbjct: 259 GSGEGVITYLLKPLSRALKDKDNIHAVIKGSAINQDGRSIGLSAPNVLAQEDVIVSAWKD 318 Query: 329 AQINPETIRYIETHGTGTILGDTIELNSIINAFQAFTSKKQFCGVGSVKTNIGHLVGASG 388 A I+PET+ YIE HGTGT LGD IE++ I AF+ +TSKKQFC +GSVKTNIGHL A+G Sbjct: 319 AGIDPETVSYIEAHGTGTKLGDPIEVDGISRAFRRYTSKKQFCSIGSVKTNIGHLDNAAG 378 Query: 389 IVSLIKAVLMLKHGEIPASLHFQTPSPYINLADSALFINDQRSKLEKGNHPVRIGINSFG 448 + ++KAVL LK+ ++PASLH++ P+ IN DS +++ND+ + E P R G++SFG Sbjct: 379 VAGMLKAVLSLKNKQLPASLHYKVPNRRINFKDSPVYVNDKLTPWETHGFPRRCGVSSFG 438 Query: 449 FSGTNCHVLLEEPPVPVYDNNAENNVFLLTLSARSSQKLVEAAQSLQRFLLTNRSVNLAD 508 FSGTNCH++LEE P V + + +LTLSA+++ L E + + ++ N V++ + Sbjct: 439 FSGTNCHIILEEAPSVVNKSIDRPCLEVLTLSAKTNDALKELVKRYRLYIQKNEDVDIGN 498 Query: 509 MCCTASQFRNHFANRLAITFSSYEDLLAKLKIIRETKELSLWSSHPGISFQLHEVVADTK 568 MC T + R HF R+A+ + +L KL + + QL + + Sbjct: 499 MCYTQNTGRWHFDYRIAVIARNTIELKNKLDKLVSIDFEDINEKEIYFGIQLDNIKQKGQ 558 Query: 569 SQIEAWEIREGEKIALDKTANEAIRE-LLQKKAGSEMLWEQAARFYIKGASMDWRPLYPG 627 + + +I+E L A++ + E +L +K ++L++ R Y++GA++DW LY G Sbjct: 559 NGLFESKIKE-----LSCEADKKLEEFILSEKTEEDVLYDICKR-YVEGANIDWDILYKG 612 Query: 628 --CRKLAMPGNVLERTKYWPAEAKRGEVYQDELYYTTEWVEESRLPAGSGAARETVLLIV 685 ++++P RT+ W A+ G +++L+Y T W ES++ S + +VLL Sbjct: 613 EDRTRISLPTYPFRRTRCW-INAEEG--LENDLFYVTAW--ESKILKKSSTIKGSVLLFR 667 Query: 686 HEADTALWEAQLPGKLR--RKRCILVEIGRPYRKINAEHYHVSNSVEDFSALCGELDISA 743 A +L LR + I V+IG Y+KIN Y +S S + +L ++DI Sbjct: 668 DSIGKA---EKLVAILRGMQVNVIEVDIGSKYKKINNSRYQISASAKAIQSLLNDIDIKD 724 Query: 744 LEQILYAAPSREGLPDSLKEFKESFNQTVMNLLYLVKALQAANTMNKDLDIALITRNAHV 803 L +++ A E + + K+ + +L +L++ A + L+I +++ + Sbjct: 725 LRYVIHMASISESSTEDISILKQKLQNGIYSLYHLLQG-TAKLGLKDRLNIVVVSEYVNK 783 Query: 804 LQPMDTGSDPFAHTLYGIGKSILQENRSFHVRHIDISNEPADLEALPAELEVPSAQYSVA 863 + + P ++G+GKS E + +R IDI + D+ + E+ ++ Sbjct: 784 ICGEENTLKPENAAMFGMGKSAFWEYPNISIRCIDIDRD-TDISVIVPEISAEGVEFCTG 842 Query: 864 LRHGRRYVEVIKRXXXXXXXXXXXXXXXXXTFXXXXXXXXXXXEVCKYLSQKN-RVKLIV 922 R+G RYVE+IK+ + E K L +N R KL Sbjct: 843 YRNGNRYVEIIKQ---ASIENKLLDIKEEGVYVITGGAGGLGIEFAKRLVLRNRRAKLAF 899 Query: 923 LGRTAIPDRESWQSIIMDNEDKQLLKKINGILAIEALGFTLDYHCVDICDEAQLRRTVEQ 982 + R+ +P+R W +I+ D+++ + +N I +EA G + D+ + ++ + + Sbjct: 900 INRSKLPERNDWDAILASGSDEKMCRLLNNIKDMEARGAEITLLSADVSEFEGMKVVISE 959 Query: 983 IRQDHGSINGVFHCAGVGVGDIEDFGMSGQEFEQRHAVKTYGSWLVYNLTQEFNTGFTLL 1042 +++ +G+ING+ H AG+ D + ++ + K G+W++ LTQE N F ++ Sbjct: 960 LKRRYGNINGIIHSAGISKRD-----ETEEDLRAVLSPKIEGAWILDRLTQEENLDFFVM 1014 Query: 1043 FSSAVSITGGRGSLAYTAGNAFVDGLAETIRLQGKNVMAINWSTWEAT--ASRLSLQADK 1100 SSA+++ GG G YTA NA++D + QGK +AINW+ WE T A +++ DK Sbjct: 1015 CSSAITLIGGLGGGGYTAANAYLDSFSAQRSSQGKRTLAINWAAWENTGLAEGMTINEDK 1074 Query: 1101 HFFEFLSTHQALQALDLIIRRGMFRTIVGKLNVQNKLLELENLWPFRLAGEIKQALFPKT 1160 F L AL A + + + R I+G+LN+ + +L L PFRL+ +K+ KT Sbjct: 1075 ELFRVLLPENALDAFENALNSNLDRVIIGELNLSSTILNLGEYLPFRLSDNLKKNTIEKT 1134 Query: 1161 RQEERPVRQTSVTVKEPEGYTATHRELAQVWADILGLTTISVFDSFHQLGGDSIHAAHLH 1220 QEE ++ + KE + YT T +A++W ++LG +V D+F LGGDSI + Sbjct: 1135 VQEEEQLKDIKLKGKEEQDYTKTEVLIAKIWGEVLGFEEFNVNDNFFTLGGDSIMITRVE 1194 Query: 1221 KQWNERHPGTLDVTDIYRYPTIHEMAGYLDSQRISQPAA 1259 + +PG + +++++ YPTI +++ YL S +IS A Sbjct: 1195 TLLEKHYPGRITISELFAYPTISKLSQYLSSSQISGKEA 1233 >B8I5I1.1 B8I5I1_CLOCE Amino acid adenylation domain protein Length = 2508 Score = 804 bits (2077), Expect = 0.0, Method: Compositional matrix adjust. Identities = 463/1253 (36%), Positives = 702/1253 (56%), Gaps = 61/1253 (4%) Query: 1299 ESDEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLA--ANQISPEG 1356 ++D AIIG + KFP AE A ++W N+ +IR E R++D + ++ + ++P+ Sbjct: 35 QNDGIAIIGMSVKFPGAETAGEYWSNIINSTDSIRKMSEERKRDIEDFMLHFTSSVNPD- 93 Query: 1357 HAYCQGGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGGTILSGTRT 1416 Y +GGYL +ID+FD +FFHISP E M PEQRL LE + A E +G GG ILSG++T Sbjct: 94 FVYPEGGYLSDIDKFDYSFFHISPNEARYMSPEQRLFLETAWSAIEDAGYGGNILSGSKT 153 Query: 1417 GVYVGK-DTTGRNEYNNRVD-ILDPLKVTSGSTGILASRIAYYLNLNGPCLVVDTACSSS 1474 G++VG D +Y + D +L L + I+ASR+AY ++L GP +++DTACSSS Sbjct: 154 GIFVGHGDAPWYGQYVLKTDPVLQSLAFAGNISSIIASRLAYLMDLKGPSMLIDTACSSS 213 Query: 1475 LTAICLATQALKQGQIDIAIVAGVSLAYLPTQ--RNSLIDSADEMIRPFDAGANGTMWGE 1532 L A+ A ++++ G+ D AI GV+L +P + + I++ D R FD + GT WGE Sbjct: 214 LVAVHNACKSIQNGECDYAIAGGVTLNIIPVKGVLDVGIEAGDFRTRSFDNNSTGTSWGE 273 Query: 1533 GAGTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPNAEAQEKVLVAAWKAANID 1592 G I+LK + A+ DN I+AVIKGS +N +G+S G+TAPN +Q V+V AWK A I+ Sbjct: 274 GVAAILLKPLERALADNDNIYAVIKGSAINQDGSSAGLTAPNMLSQADVIVKAWKEAGIN 333 Query: 1593 PETISYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAGTVKANIGHLVGASGMASV 1652 PETISYIEAH +GTKLGD IE++ I AF R+T+KRQFCA G+VK NIGHL G SG+A + Sbjct: 334 PETISYIEAHGSGTKLGDTIEIEAIKRAFSRYTSKRQFCALGSVKTNIGHLGGTSGIAGL 393 Query: 1653 IKMIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWSGSAAPRRCGISSFGFSGT 1712 IK ++A K+ +LPP++ PN I+F DSP+Y+N+RL+DW+ RRCG+SSFG SGT Sbjct: 394 IKAVLALKNCELPPMINLSFPNREIDFVDSPVYLNNRLEDWTTEGVARRCGVSSFGLSGT 453 Query: 1713 NCHILLEEPPVFTNPQEAKQDWHILALSAKTAGSLSALIKRYFHMINGTVTLDLQNLCFT 1772 NCH++LEE A I LSAK+ SL L+K+Y ++ +L ++CFT Sbjct: 454 NCHVVLEEAVRKDTETSANPGPFIFTLSAKSENSLKQLVKQYKDYVSRESIPNLGDICFT 513 Query: 1773 ANISRGHYEHRIVLLFRTENELRAKFKYLQEAGILQAADRDQRIYYKA------SRISYD 1826 A+ R HY +RI L + K L D + + A + +SY Sbjct: 514 ASNGRAHYNYRIAFLAEDSEDFIKKINGLDIHDFRMNLDGEAVCCHYAKFKDEGNEVSYI 573 Query: 1827 QEGFDGDGL----LEQDKLKLNKLAESLIEEWSVEETLSAVDNLHKIARLYTDGADINWD 1882 +G +G L E+ K LNK E+ + + L ++ +LY GA I+W Sbjct: 574 LDGENGKSLKTHIFEKAKAILNKYMEN-----------KSREQLEELCKLYVIGASIDWS 622 Query: 1883 RLYQGKQHRLTELPAYAYEPVRHWIGGSARKGSSSPGK------YYQLQWLPDHREQPAG 1936 RLY ++ LP Y +E R W+ ++S G Y+ +W+P P Sbjct: 623 RLYSSGKYFRKRLPVYQFERERCWVESKKSIRNTSSGDVGFNHLYFGTEWVPSGT-IPGN 681 Query: 1937 IKPDEGAWLFVGGTGTKSQELLRVLRKQEIELIEVTPGARYHQLAANRYSI-GSGEEYSL 1995 +G L + S +L+ L+ + +IE+ G+ Y +L+ Y I GS +Y Sbjct: 682 WGSQDGYTLILKNQSEFSDDLIEKLKDKYKYVIEIVSGSNYERLSDTSYIINGSRADYDK 741 Query: 1996 LLKELSNRGIKHVIHCLSLA-DEKIAGIEDLHAAENRGVYNLHHLVTALLNGQYHQELNL 2054 L +L + I +IH LSL + + I +L A GV +L HL +L++ E+++ Sbjct: 742 LFHDLKDIHISKIIHMLSLERNRSVDSIYELEEAVENGVMSLFHLCRSLIDNDIKNEIDV 801 Query: 2055 FFVADHTFLVNRHEPVLNPHHAVLFGMAKVIPQEYPQFKCRCIDIDSATAPATVWKEICS 2114 ++D+ V E +NP +A LFG+ K++ QEY KCR IDID T T+ EI Sbjct: 802 VLISDYITRVTGEEEYINPENASLFGLGKIMDQEYGHLKCRAIDIDENTKIETLLNEISC 861 Query: 2115 GKGDFQVAYRDNTRYLEHFGERRLEAAEAGGVSLKENGVYVVTGGLGGIGLAVAQYLSGK 2174 G + VAYR+ RY+E F + +L + L ENG YV+TGG GGIGL +A+YLS Sbjct: 862 GYQSYHVAYRNGERYIEKFKKIKLSEYGKEDIKLVENGAYVITGGTGGIGLEIAKYLSAL 921 Query: 2175 QRVHLCLLNRRTLPPG---PSQSQR------------IRQIEANGSDVDLYSVDISAPNE 2219 +++++ L+ LP P +R I QIE G+ VD YS D+S E Sbjct: 922 KKINIVLIGVSKLPERHLWPDIIERGQEKKLCTKLEGIIQIEKLGASVDYYSADVSDEFE 981 Query: 2220 LQGVLQAIRTKYGQINGLFHCAGIAGEGLLINKGKPEIKRVLDAKVTGTWLLDQYTAQDH 2279 ++ V+ IR +YG+ING+ H AGIAG+G +I K + ++VL K+ GTWLLD+ T +D Sbjct: 982 MRTVISRIRGEYGRINGVVHSAGIAGDGFIIRKDEKAFRKVLAPKIKGTWLLDRLTIEDK 1041 Query: 2280 LDYFVLFSSVTSLLGGMGQADYTAANAYLDGFSDYRQANNRRSVTINWPAWKEVGMTLKY 2339 D+F++FSS S+ G G+ DYTAAN+YLD ++ +R +++TINW WK+VGM + Sbjct: 1042 PDFFIMFSSAVSIFGAPGEGDYTAANSYLDSYTWHRSGRG-KTLTINWTGWKDVGMIVNL 1100 Query: 2340 DIQEGRSPFLGLTEEQGISILDAVLQRKLSRIIAGEI---NERYFQNGDPSLPFAVPPQM 2396 +I S L ++ V+ RK+SR++ GEI NE + + G ++ + Sbjct: 1101 EIDTEGSKV--LPTRLAVNAFGLVINRKMSRVMIGEIDYDNEIHSKFGANAIMLSDEILQ 1158 Query: 2397 ISRGTGAFNPQEKVIADEPILPILKGRYDHSYNSYEISLAAMWQKVLGVAEVNVHLPFQE 2456 ++ A + + V+A+ I L GR + +Y+ E +A +W +LG + F E Sbjct: 1159 ENKAKNAQSGFDTVVAENEIK--LSGRQNENYSETEKRVANIWGSILGYDRIRTSDNFFE 1216 Query: 2457 TGGNSILATSLVKEIDGVYPGCVNIATLFAYPSIAKMAEYLKQ-KQSENESLQ 2508 GG+SI+A V I+ + + ++ L P + ++L++ ++E ++L Sbjct: 1217 LGGDSIIAMKAVNSINKLMGLKIVVSDLLRNPGFTEFVKFLEESSEAETDALN 1269 Score = 666 bits (1719), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/1291 (33%), Positives = 676/1291 (52%), Gaps = 53/1291 (4%) Query: 2 MDKLKKYIYELVASKKLTAKEATEYITYLQNGNEHRSEEIAVVGISGRFPKADRVEQFWD 61 MDK+ + I+E + K+ + E + L N+ +++ IA++G+S +FP A+ ++W Sbjct: 1 MDKIAQIIFENSVAGKIDKQVGAELLK-LLKTNKKQNDGIAIIGMSVKFPGAETAGEYWS 59 Query: 62 NLCSGRDCLDTFPEDR--------LHDGQALAPERHLAGGSLKQGGYLDEISFFDAEMFR 113 N+ + D + E+R LH ++ P+ +GGYL +I FD F Sbjct: 60 NIINSTDSIRKMSEERKRDIEDFMLHFTSSVNPDF-----VYPEGGYLSDIDKFDYSFFH 114 Query: 114 ISPKEALSMEPYQRIMLEVAYDTLVNAGYETQDILGSKTGVFIGRDHVTGIEYRNYAAP- 172 ISP EA M P QR+ LE A+ + +AGY + GSKTG+F+G H Y Y Sbjct: 115 ISPNEARYMSPEQRLFLETAWSAIEDAGYGGNILSGSKTGIFVG--HGDAPWYGQYVLKT 172 Query: 173 ----DIFRLTGGWPGILASRISYVYNLKGPSVVFDTSCSSGLVGLHFACESLRRNECDMA 228 G I+ASR++Y+ +LKGPS++ DT+CSS LV +H AC+S++ ECD A Sbjct: 173 DPVLQSLAFAGNISSIIASRLAYLMDLKGPSMLIDTACSSSLVAVHNACKSIQNGECDYA 232 Query: 229 FVGGISGLFYFPPVKEDGSLDQ-VESAEEKIRAFDKAAEGTVWGEGCGGLLLKPLSKAVA 287 GG++ PVK G LD +E+ + + R+FD + GT WGEG +LLKPL +A+A Sbjct: 233 IAGGVT--LNIIPVK--GVLDVGIEAGDFRTRSFDNNSTGTSWGEGVAAILLKPLERALA 288 Query: 288 DKDVIYAVIKGSGINNNGLSKGITAPNGEAQEELLKKVWKQAQINPETIRYIETHGTGTI 347 D D IYAVIKGS IN +G S G+TAPN +Q +++ K WK+A INPETI YIE HG+GT Sbjct: 289 DNDNIYAVIKGSAINQDGSSAGLTAPNMLSQADVIVKAWKEAGINPETISYIEAHGSGTK 348 Query: 348 LGDTIELNSIINAFQAFTSKKQFCGVGSVKTNIGHLVGASGIVSLIKAVLMLKHGEIPAS 407 LGDTIE+ +I AF +TSK+QFC +GSVKTNIGHL G SGI LIKAVL LK+ E+P Sbjct: 349 LGDTIEIEAIKRAFSRYTSKRQFCALGSVKTNIGHLGGTSGIAGLIKAVLALKNCELPPM 408 Query: 408 LHFQTPSPYINLADSALFINDQRSKLEKGNHPVRIGINSFGFSGTNCHVLLEEPPVPVYD 467 ++ P+ I+ DS +++N++ R G++SFG SGTNCHV+LEE + Sbjct: 409 INLSFPNREIDFVDSPVYLNNRLEDWTTEGVARRCGVSSFGLSGTNCHVVLEEAVRKDTE 468 Query: 468 NNAENNVFLLTLSARSSQKLVEAAQSLQRFLLTNRSVNLADMCCTASQFRNHFANRLAIT 527 +A F+ TLSA+S L + + + ++ NL D+C TAS R H+ R+A Sbjct: 469 TSANPGPFIFTLSAKSENSLKQLVKQYKDYVSRESIPNLGDICFTASNGRAHYNYRIAFL 528 Query: 528 FSSYEDLLAKLKIIR-ETKELSLWSSHPGISFQLHEVVADTKSQIEAWEIREGEKIALDK 586 ED + K+ + ++L + + + S I E + K + + Sbjct: 529 AEDSEDFIKKINGLDIHDFRMNLDGEAVCCHYAKFKDEGNEVSYILDGENGKSLKTHIFE 588 Query: 587 TANEAIRELLQKKAGSEMLWEQAARFYIKGASMDWRPLYPGCR--KLAMPGNVLERTKYW 644 A + + ++ K+ ++ E+ + Y+ GAS+DW LY + + +P ER + W Sbjct: 589 KAKAILNKYMENKSREQL--EELCKLYVIGASIDWSRLYSSGKYFRKRLPVYQFERERCW 646 Query: 645 PAEAKR-------GEVYQDELYYTTEWVEESRLPAGSGAARETVLLIVHEADTALWEAQL 697 E+K+ G+V + LY+ TEWV +P G+ L++ ++++ + L Sbjct: 647 -VESKKSIRNTSSGDVGFNHLYFGTEWVPSGTIPGNWGSQDGYTLILKNQSE---FSDDL 702 Query: 698 PGKLRRKRCILVEI--GRPYRKINAEHYHVSNSVEDFSALCGEL-DISALEQILYAAPSR 754 KL+ K ++EI G Y +++ Y ++ S D+ L +L DI + I + R Sbjct: 703 IEKLKDKYKYVIEIVSGSNYERLSDTSYIINGSRADYDKLFHDLKDIHISKIIHMLSLER 762 Query: 755 EGLPDSLKEFKESFNQTVMNLLYLVKALQAANTMNKDLDIALITRNAHVLQPMDTGSDPF 814 DS+ E +E+ VM+L +L ++L N + ++D+ LI+ + + +P Sbjct: 763 NRSVDSIYELEEAVENGVMSLFHLCRSL-IDNDIKNEIDVVLISDYITRVTGEEEYINPE 821 Query: 815 AHTLYGIGKSILQENRSFHVRHIDISNEPADLEALPAELEVPSAQYSVALRHGRRYVEVI 874 +L+G+GK + QE R IDI +E +E L E+ Y VA R+G RY+E Sbjct: 822 NASLFGLGKIMDQEYGHLKCRAIDI-DENTKIETLLNEISCGYQSYHVAYRNGERYIEKF 880 Query: 875 KRXXXXXXXXXXXXXXXXXTFXXXXXXXXXXXEVCKYLSQKNRVKLIVLGRTAIPDRESW 934 K+ + E+ KYLS ++ ++++G + +P+R W Sbjct: 881 KKIKLSEYGKEDIKLVENGAYVITGGTGGIGLEIAKYLSALKKINIVLIGVSKLPERHLW 940 Query: 935 QSIIMDNEDKQLLKKINGILAIEALGFTLDYHCVDICDEAQLRRTVEQIRQDHGSINGVF 994 II ++K+L K+ GI+ IE LG ++DY+ D+ DE ++R + +IR ++G INGV Sbjct: 941 PDIIERGQEKKLCTKLEGIIQIEKLGASVDYYSADVSDEFEMRTVISRIRGEYGRINGVV 1000 Query: 995 HCAGVGVGDIEDFGMSGQEFEQRHAVKTYGSWLVYNLTQEFNTGFTLLFSSAVSITGGRG 1054 H AG+ GD + F + A K G+WL+ LT E F ++FSSAVSI G G Sbjct: 1001 HSAGIA-GDGFIIRKDEKAFRKVLAPKIKGTWLLDRLTIEDKPDFFIMFSSAVSIFGAPG 1059 Query: 1055 SLAYTAGNAFVDGLAETIRLQGKNVMAINWSTWEATASRLSLQADKHFFEFLSTHQALQA 1114 YTA N+++D +GK + INW+ W+ ++L+ D + L T A+ A Sbjct: 1060 EGDYTAANSYLDSYTWHRSGRGK-TLTINWTGWKDVGMIVNLEIDTEGSKVLPTRLAVNA 1118 Query: 1115 LDLIIRRGMFRTIVGKLNVQNKLLELENLWPFRLAGEIKQALFPKTRQE--ERPVRQTSV 1172 L+I R M R ++G+++ N++ L+ EI Q K Q + V + + Sbjct: 1119 FGLVINRKMSRVMIGEIDYDNEIHSKFGANAIMLSDEILQENKAKNAQSGFDTVVAENEI 1178 Query: 1173 TV--KEPEGYTATHRELAQVWADILGLTTISVFDSFHQLGGDSIHAAHLHKQWNERHPGT 1230 + ++ E Y+ T + +A +W ILG I D+F +LGGDSI A N+ Sbjct: 1179 KLSGRQNENYSETEKRVANIWGSILGYDRIRTSDNFFELGGDSIIAMKAVNSINKLMGLK 1238 Query: 1231 LDVTDIYRYPTIHEMAGYLDSQRISQPAALN 1261 + V+D+ R P E +L+ ++ ALN Sbjct: 1239 IVVSDLLRNPGFTEFVKFLEESSEAETDALN 1269 >B8I5I2.1 B8I5I2_CLOCE Beta-ketoacyl synthase Length = 1298 Score = 728 bits (1880), Expect = 0.0, Method: Compositional matrix adjust. Identities = 443/1299 (34%), Positives = 685/1299 (52%), Gaps = 84/1299 (6%) Query: 1302 EYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLAANQISPEGHAYCQ 1361 + A+IG A K AE ++ W+NL GV + PE R+KD YL Q Sbjct: 25 DIAVIGIAVKLSKAETVDELWQNLKAGVDCVGEIPEERKKDITAYLDFISTGESQKTIGQ 84 Query: 1362 GGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGGTILSGTRTGVYVG 1421 +++E+D+FD FF +SP+E LMDP QRL LE ++A + +G GG + T TG+++G Sbjct: 85 AAFIKEVDKFDYGFFKLSPKEAGLMDPNQRLFLEVAWKAIQDAGYGGNKIKDTNTGIFLG 144 Query: 1422 KDTTGRNEYNNRVDILDPLKVTSGSTG----ILASRIAYYLNLNGPCLVVDTACSSSLTA 1477 +Y + ++P ++ + G ++A RI+Y LNL GP +++DT CSSSL A Sbjct: 145 --CGADCDYKEMISKVEPQSISVAAVGNLRPVIAGRISYILNLKGPTMLIDTTCSSSLVA 202 Query: 1478 ICLATQALKQGQIDIAIVAGVSLAYLPTQRNSL-IDSADEMIRPFDAGANGTMWGEGAGT 1536 + LA ++L + D+AI G+ L LP ++ + S+D + FD ++GT GEG Sbjct: 203 VHLACRSLINRECDMAIAGGIQLHILPVKQTDIGTSSSDGRTKTFDFDSDGTGTGEGVLA 262 Query: 1537 IILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPNAEAQEKVLVAAWKAANIDPETI 1596 +ILK +S+A+ D I+AVIKGS +N++G+S G+TAP+A AQE V++ AW+ A I+PETI Sbjct: 263 VILKPLSKAILDMDNIYAVIKGSAINSDGSSLGLTAPSASAQESVIIKAWEDAGINPETI 322 Query: 1597 SYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAGTVKANIGHLVGASGMASVIKMI 1656 SYIEAH TGT+LGDPIE++GI AF RFTN+ FCA G+ K+N GHL A+G+ +K + Sbjct: 323 SYIEAHGTGTRLGDPIEIEGIKKAFGRFTNRTGFCAVGSAKSNYGHLDSAAGILGFVKAV 382 Query: 1657 MAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWSGSAAPRRCGISSFGFSGTNCHI 1716 ++ KHK +P L F PN I+F DSP+YV D+ +W S RRCG+SSFG SGTN HI Sbjct: 383 LSLKHKTIPKNLHFNKPNAEIDFIDSPVYVADKTAEWERSGDKRRCGVSSFGISGTNSHI 442 Query: 1717 LLEEPP------VFTNPQEAKQDWHILALSAKTAGSLSALIKRYFHMINGTVTLDLQNLC 1770 +LEE P VF + + + +SA++ +L L+ +Y + D ++C Sbjct: 443 VLEEAPELREHKVFQDSETG-----VFTVSARSQTALKTLVAQYIGYLEACKAEDFHSIC 497 Query: 1771 FTANISRGHYEHRIVLLFRTENELRAKFKYLQEAGILQAADRDQRIYYKAS-RISYDQEG 1829 +TAN R HY +R+ +L + +EL + + +G + IYY A I D+ Sbjct: 498 YTANTGREHYNYRLSVLADSLDELLLRLNFFLNSGAYSF--ENAYIYYGAYFMIDKDRPR 555 Query: 1830 FDGDGLLEQDKLKLNKLAESLIEEWSVEETLSAVDNLHKIARLYTDGADINWDRLYQGKQ 1889 +++ ++ A++ +EE+ + + + LH++ LYT GA+I W+RLY G+ Sbjct: 556 TGVFDFTDKEIKEITNSAKTKMEEFLLNKNRQEL--LHELMELYTKGAEIEWERLYTGEG 613 Query: 1890 HRLTELPAYAYEPVRHWIG--GSARKGSSSPGKYYQLQWLPDHREQPAGIKPDEGAWLFV 1947 R LPAY +E R WI SA+ S Y+ W+ D + G L Sbjct: 614 RRKISLPAYPFEKNRCWINIPHSAQSMVQSQDILYENVWIHDETCLETTDLLERGTVLVF 673 Query: 1948 GGTGTKSQELLRVLRKQEIELIEVTPGARYHQLAANRY-SIGSGEEYSLLLKELSNRGIK 2006 G +++ L++ +LI+V G + L N Y + + Y LL+ LS I Sbjct: 674 GERCQLYNSIVKGLQESGDQLIQVFKGTEFKDLGKNSYECVNTRGGYEKLLEVLSCENIT 733 Query: 2007 HVIHCLSLADE-KIAGIEDLHAAENRGVYNLHHLVTALLNGQYHQELNLFFVADHTFLVN 2065 V++ E +I E + + G+Y A Q + V+ + Sbjct: 734 RVLYLTPREKEIEINSPEQFESNLDDGLYAFFRFTAAFARKFAGQRVEFVLVSRPVNEII 793 Query: 2066 RHEPVLNPHHAVLFGMAKVIPQEYPQFKCRCIDIDSATAPATVWKEICSGKGDFQVAYRD 2125 HE + P + + G+ V+P EYP F RCI++D T A + KEI S K F+VAYR Sbjct: 794 GHEDIY-PDDSAITGVGMVLPFEYPGFSSRCIELDKETPYANIIKEIRSQKKYFKVAYRK 852 Query: 2126 NTRYLEHFGERRLEAAEAGGVSLKENGVYVVTGGLGGIGLAVAQYLSGKQRVHLCLLNRR 2185 RY+E + + + + KENG YV+TGGLG IG +A +++ + ++ L+ R Sbjct: 853 GKRYVEQLQSIQKDMVQKSNIYFKENGTYVITGGLGDIGTKLAVHVAKRHNANIILIGRT 912 Query: 2186 TLPPGPSQSQRIRQIEANGSD-------------------VDLYSVDISAPNELQGVLQA 2226 LP + + + I +NG D V Y+ DIS EL VL+A Sbjct: 913 KLP----EREYWKDIVSNGRDTVLSGKLEAMEKLEKFSCKVAYYTADISLERELSEVLEA 968 Query: 2227 IRTKYGQINGLFHCAGIAGE--GLLINKGKPEIKR-VLDAKVTGTWLLDQYTAQDHLDYF 2283 IR K+G+ING+ HCAG+ G +I + E R VL K+ GTWLLD+ T +D+LD+F Sbjct: 969 IRNKHGKINGIIHCAGVGANMTGRIIGEETEETFREVLKPKLRGTWLLDKLTRKDNLDFF 1028 Query: 2284 VLFSSVTSLLGGMGQADYTAANAYLDGFSDYRQANNRRSVTINWPAWKEVGMTLKYDIQE 2343 ++FSS +L+GG G + YTAAN YLD +S R+ + + + ++W W E Sbjct: 1029 IMFSSAITLIGGRGSSHYTAANCYLDAYSFKRKTSVTKYMALDWAPWYRSDSIGDKKTFE 1088 Query: 2344 GRSPFLGLTEEQGISILDAVLQRKLSRIIAGEIN-ERYFQNGDPSLPFAVPPQMISRGTG 2402 + F L + + D + L ++IAGE+N + + LPF ++ Sbjct: 1089 EKHIFKVLPQAAALKAFDETICLNLPKVIAGELNMDAALFKLEDFLPFNFSSEL------ 1142 Query: 2403 AFNPQEKVIADEP--ILP--------ILKGRYDHSYNSYEISLAAMWQKVLGVAEVNVHL 2452 +EK+ A + ILP L G+ Y+ E +A +W VLG +++++ Sbjct: 1143 ----KEKIDAHQKKTILPEKSHKQELTLTGKSSGEYSEAERKIAGIWGSVLGYKQLSIYN 1198 Query: 2453 PFQETGGNSILATSLVKEIDGVYPGCVNIATLFAYPSIAKMAEYL------KQKQSENES 2506 F E GG+SILA S+ + + + ++IA +FAYP+IAKMAEY+ K +S Sbjct: 1199 NFFEMGGDSILAASIHERLKKEFSQNISIADIFAYPTIAKMAEYISGFESKKPSKSTQLD 1258 Query: 2507 LQEADPKTAKRMELSDKLSGFVEGKVPIENILQYLDNNE 2545 L + + +L D +S +G++ I+N L L + E Sbjct: 1259 LNKENNINENIFDLFDMVS---KGEMSIDNALDRLSSME 1294 Score = 623 bits (1607), Expect = e-176, Method: Compositional matrix adjust. Identities = 402/1265 (31%), Positives = 662/1265 (52%), Gaps = 62/1265 (4%) Query: 35 EHRSEEIAVVGISGRFPKADRVEQFWDNLCSGRDCLDTFPEDRLHDGQALAPERHLAGG- 93 E ++IAV+GI+ + KA+ V++ W NL +G DC+ PE+R D A ++ G Sbjct: 20 EISCKDIAVIGIAVKLSKAETVDELWQNLKAGVDCVGEIPEERKKDITAYLD--FISTGE 77 Query: 94 ---SLKQGGYLDEISFFDAEMFRISPKEALSMEPYQRIMLEVAYDTLVNAGYETQDILGS 150 ++ Q ++ E+ FD F++SPKEA M+P QR+ LEVA+ + +AGY I + Sbjct: 78 SQKTIGQAAFIKEVDKFDYGFFKLSPKEAGLMDPNQRLFLEVAWKAIQDAGYGGNKIKDT 137 Query: 151 KTGVFIG-------RDHVTGIEYRNYAAPDIFRLTGGWPGILASRISYVYNLKGPSVVFD 203 TG+F+G ++ ++ +E ++ + + G ++A RISY+ NLKGP+++ D Sbjct: 138 NTGIFLGCGADCDYKEMISKVEPQSISVAAV----GNLRPVIAGRISYILNLKGPTMLID 193 Query: 204 TSCSSGLVGLHFACESLRRNECDMAFVGGISGLFYFPPVKEDGSLDQVESAEEKIRAFDK 263 T+CSS LV +H AC SL ECDMA GGI + PVK+ S++ + + FD Sbjct: 194 TTCSSSLVAVHLACRSLINRECDMAIAGGIQ--LHILPVKQTDI--GTSSSDGRTKTFDF 249 Query: 264 AAEGTVWGEGCGGLLLKPLSKAVADKDVIYAVIKGSGINNNGLSKGITAPNGEAQEELLK 323 ++GT GEG ++LKPLSKA+ D D IYAVIKGS IN++G S G+TAP+ AQE ++ Sbjct: 250 DSDGTGTGEGVLAVILKPLSKAILDMDNIYAVIKGSAINSDGSSLGLTAPSASAQESVII 309 Query: 324 KVWKQAQINPETIRYIETHGTGTILGDTIELNSIINAFQAFTSKKQFCGVGSVKTNIGHL 383 K W+ A INPETI YIE HGTGT LGD IE+ I AF FT++ FC VGS K+N GHL Sbjct: 310 KAWEDAGINPETISYIEAHGTGTRLGDPIEIEGIKKAFGRFTNRTGFCAVGSAKSNYGHL 369 Query: 384 VGASGIVSLIKAVLMLKHGEIPASLHFQTPSPYINLADSALFINDQRSKLEKGNHPVRIG 443 A+GI+ +KAVL LKH IP +LHF P+ I+ DS +++ D+ ++ E+ R G Sbjct: 370 DSAAGILGFVKAVLSLKHKTIPKNLHFNKPNAEIDFIDSPVYVADKTAEWERSGDKRRCG 429 Query: 444 INSFGFSGTNCHVLLEEPPV----PVYDNNAENNVFLLTLSARSSQKLVEAAQSLQRFLL 499 ++SFG SGTN H++LEE P V+ ++E VF T+SARS L +L Sbjct: 430 VSSFGISGTNSHIVLEEAPELREHKVF-QDSETGVF--TVSARSQTALKTLVAQYIGYLE 486 Query: 500 TNRSVNLADMCCTASQFRNHFANRLAITFSSYEDLLAKLKIIRETKELSLWSSHPGISFQ 559 ++ + +C TA+ R H+ RL++ S ++LL +L + S +++ I + Sbjct: 487 ACKAEDFHSICYTANTGREHYNYRLSVLADSLDELLLRLNFFLNSGAYSFENAY--IYYG 544 Query: 560 LHEVVADTKSQIEAWEIREGEKIALDKTANEAIRELLQKKAGSEMLWEQAARFYIKGASM 619 + ++ + + ++ + E + +A + E L K E+L E Y KGA + Sbjct: 545 AYFMIDKDRPRTGVFDFTDKEIKEITNSAKTKMEEFLLNKNRQELLHE-LMELYTKGAEI 603 Query: 620 DWRPLYP--GCRKLAMPGNVLERTKYW---PAEAKRGEVYQDELYYTTEWVEESRLPAGS 674 +W LY G RK+++P E+ + W P A+ QD LY +E+ L Sbjct: 604 EWERLYTGEGRRKISLPAYPFEKNRCWINIPHSAQSMVQSQDILYENVWIHDETCLETTD 663 Query: 675 GAARETVLLIVHEADTALWEAQLPGKLRRKRCILVEI--GRPYRKINAEHYHVSNSVEDF 732 R TVL+ L+ + + G L+ L+++ G ++ + Y N+ + Sbjct: 664 LLERGTVLVFGERCQ--LYNSIVKG-LQESGDQLIQVFKGTEFKDLGKNSYECVNTRGGY 720 Query: 733 SALCGELDISALEQILYAAPSREGLPDSLKEFKESFNQTVMNLLYLVKALQAANTMNKDL 792 L L + ++LY P + + + E ES + + A A + + Sbjct: 721 EKLLEVLSCENITRVLYLTPREKEIEINSPEQFESNLDDGLYAFFRFTAAFARKFAGQRV 780 Query: 793 DIALITRNAH-VLQPMDTGSDPFAHTLYGIGKSILQENRSFHVRHIDISNEPADLEALPA 851 + L++R + ++ D D A T G+G + E F R I++ E + Sbjct: 781 EFVLVSRPVNEIIGHEDIYPDDSAIT--GVGMVLPFEYPGFSSRCIELDKETP-YANIIK 837 Query: 852 ELEVPSAQYSVALRHGRRYVEVIKRXXXXXXXXXXXXXXXXXTFXXXXXXXXXXXEVCKY 911 E+ + VA R G+RYVE ++ T+ ++ + Sbjct: 838 EIRSQKKYFKVAYRKGKRYVEQLQSIQKDMVQKSNIYFKENGTYVITGGLGDIGTKLAVH 897 Query: 912 LSQKNRVKLIVLGRTAIPDRESWQSIIMDNEDKQLLKKINGILAIEALGFTLDYHCVDIC 971 +++++ +I++GRT +P+RE W+ I+ + D L K+ + +E + Y+ DI Sbjct: 898 VAKRHNANIILIGRTKLPEREYWKDIVSNGRDTVLSGKLEAMEKLEKFSCKVAYYTADIS 957 Query: 972 DEAQLRRTVEQIRQDHGSINGVFHCAGVG---VGDIEDFGMSGQE-FEQRHAVKTYGSWL 1027 E +L +E IR HG ING+ HCAGVG G I G +E F + K G+WL Sbjct: 958 LERELSEVLEAIRNKHGKINGIIHCAGVGANMTGRI--IGEETEETFREVLKPKLRGTWL 1015 Query: 1028 VYNLTQEFNTGFTLLFSSAVSITGGRGSLAYTAGNAFVDGLAETIRLQGKNVMAINWSTW 1087 + LT++ N F ++FSSA+++ GGRGS YTA N ++D + + MA++W+ W Sbjct: 1016 LDKLTRKDNLDFFIMFSSAITLIGGRGSSHYTAANCYLDAYSFKRKTSVTKYMALDWAPW 1075 Query: 1088 ---EATASRLSLQADKHFFEFLSTHQALQALDLIIRRGMFRTIVGKLNVQNKLLELENLW 1144 ++ + + + +KH F+ L AL+A D I + + I G+LN+ L +LE+ Sbjct: 1076 YRSDSIGDKKTFE-EKHIFKVLPQAAALKAFDETICLNLPKVIAGELNMDAALFKLEDFL 1134 Query: 1145 PFRLAGEIKQALFPKTRQ----EERPVRQTSVTVKEPEGYTATHRELAQVWADILGLTTI 1200 PF + E+K+ + ++ E+ ++ ++T K Y+ R++A +W +LG + Sbjct: 1135 PFNFSSELKEKIDAHQKKTILPEKSHKQELTLTGKSSGEYSEAERKIAGIWGSVLGYKQL 1194 Query: 1201 SVFDSFHQLGGDSIHAAHLHKQWNERHPGTLDVTDIYRYPTIHEMAGYL---DSQRISQP 1257 S++++F ++GGDSI AA +H++ + + + DI+ YPTI +MA Y+ +S++ S+ Sbjct: 1195 SIYNNFFEMGGDSILAASIHERLKKEFSQNISIADIFAYPTIAKMAEYISGFESKKPSKS 1254 Query: 1258 AALNL 1262 L+L Sbjct: 1255 TQLDL 1259 >A7Z4Y6.1 A7Z4Y6_BACA2 BaeL Length = 4475 Score = 647 bits (1669), Expect = 0.0, Method: Compositional matrix adjust. Identities = 503/1751 (28%), Positives = 833/1751 (47%), Gaps = 183/1751 (10%) Query: 16 KKLTAKEATEYITYLQNGNEHRSEEIAVVGISGRFPKADRVEQFWDNLCSGRDCLDTFPE 75 ++LT ++ E + + + ++ IA+VG+SG++P A ++ +WDNL ++ + P Sbjct: 2813 ERLTIQKEPEPVQAKREPKDEIADAIAIVGMSGKYPDAPELKTYWDNLARAKNAIRDIPL 2872 Query: 76 DRLHDGQALAPERHLAGGS-LKQGGYLDEISFFDAEMFRISPKEALSMEPYQRIMLEVAY 134 R + P + G + G LD+I FD F ISP EA M+P RI L+ + Sbjct: 2873 SRWDVNKYYDPALNKKGKVYCRSIGMLDDIEEFDPLFFNISPSEAELMDPQHRIFLQEGF 2932 Query: 135 DTLVNAGYETQDILGSKTGVFIG-RDHVTGIEYRNYAAPDIFRLTGGWPGILASRISYVY 193 +AGY ++++ G GV++G ++ G+ + TG I A+R+ Y Sbjct: 2933 KAFEDAGYSSKELNGKNCGVYLGIMNNEYGMMLNKHQTGG--SATGNSFSIAAARLPYYL 2990 Query: 194 NLKGPSVVFDTSCSSGLVGLHFACESLRRNECDMAFVGGISGLFYFPP-----VKEDGSL 248 NLKGP++ DT+CSS LVG H A ++L +E DMA VGG++ Y P + E G L Sbjct: 2991 NLKGPAIPIDTACSSSLVGAHLARQALLNHEIDMALVGGVT--LYLTPESYISMCEAGML 3048 Query: 249 DQVESAEEKIRAFDKAAEGTVWGEGCGGLLLKPLSKAVADKDVIYAVIKGSGINNNGLSK 308 S + + +AFD +A G V GEG G L+LK L A AD+D IY VI GSGIN +G + Sbjct: 3049 ----SPDGQCKAFDNSANGFVPGEGAGALVLKRLKDAEADQDHIYGVIIGSGINQDGKTN 3104 Query: 309 GITAPNGEAQEELLKKVWKQAQINPETIRYIETHGTGTILGDTIELNSIINAFQAFTSKK 368 GITAP+ ++Q +L ++V++ I+PE+I Y E HGTGT GD IEL ++ + F+ T +K Sbjct: 3105 GITAPSAKSQMDLERQVYEAHNIHPESITYAEMHGTGTKQGDPIELEALSSVFKEKTDRK 3164 Query: 369 QFCGVGSVKTNIGHLVGASGIVSLIKAVLMLKHGEIPASLHFQTPSPYINLADSALFIND 428 QFC +GSVK+NIGH A+G+ S+ K +L +KH ++ +LHF TP+ + + DS LF+N Sbjct: 3165 QFCAIGSVKSNIGHTSAAAGVASVQKVLLSMKHQQLVPTLHFSTPNEHFDFDDSPLFVNT 3224 Query: 429 QRSKLEKGNHPVRIGINSFGFSGTNCHVLLEE--PPVPVYDNNAENNVFLLTLSARSSQK 486 + E G P R ++SFG+SGTN H+++EE P E N+F+L SA+ + + Sbjct: 3225 ELKPWETGGAPRRACVSSFGYSGTNAHLVIEEYQPKDRGSRKPDETNIFVL--SAKKAPQ 3282 Query: 487 LVEAAQSLQRFLLTNRSVNLADMCCTASQFRNHFANRLAITFSSYEDLLAKL-KIIRETK 545 + A+S+ F ++++NL+DM T R+ RLA+T S E+L+++L + Sbjct: 3283 VKTYAESVIEFAKADQNINLSDMAYTLQTGRDAMDYRLAVTAGSREELISRLTDFVNGNT 3342 Query: 546 ELSLWSSHPGISFQLHEVVADTKSQIEAWEIREGEKIALDKTANEAIRELLQKKAGSEML 605 ++ +H + K +I+A+E D + +R KK Sbjct: 3343 GEGIYEAH----------IKTAKKEIKAFET--------DDDLKQLVRSWFDKKK----- 3379 Query: 606 WEQAARFYIKGASMDWRPLYPG--CRKLAMPGNVLERTKYWPAEAK----RGEVYQDELY 659 + + A + KG MDW LY G R++++P + YW E K E ++ + Sbjct: 3380 YAKIAELWAKGLQMDWDRLYQGEKPRRISLPAYPFAKEPYWLPEPKVIPQETEDRREAVL 3439 Query: 660 YTTEWVEESRLPAGSGAARETVLLIVHEADTALWEAQLPGKLRRKRCILVEIGRPYRKIN 719 +WV AG + R ++I+ +A TA + + V+ Sbjct: 3440 LEKQWVPCEIDSAGEKSGR--TVMILADARTAELAEETAKHFADSFILPVD--------- 3488 Query: 720 AEHYHVSNSVEDFSALCGELDISALEQILYAAPSREGLPDSLKEFKESFNQT-VMNLLYL 778 + D++ + G +D++ PS EG+ S Q + LLY+ Sbjct: 3489 ----SADTAASDWNHIDGAIDLTGCGD---EDPSLEGISRLQTLIDTSRRQARPLTLLYV 3541 Query: 779 VKALQAANTMNKDLDIALITRNAHVLQPMDTGSDPFAHTLYGIGKSILQENRSFHVRHID 838 K L+ K + +A ++ G+ + + E ++ RH+D Sbjct: 3542 TKGLEPFQ--QKTIHLAGAAKS-------------------GLYRMLQNEYQNVTSRHMD 3580 Query: 839 ISNEPADLEALPA----ELEVPSAQYSVALRHGRRYVEVIKRXXXXXXXXXXXXXXXXXT 894 +++ D + L E + + R+G+RY + + Sbjct: 3581 -ADKDTDQQTLAKQIADEFSADCTEPEICRRNGQRYRALFREIPSGKRAEHKPAPFPEDH 3639 Query: 895 FXXXXXXXXXXXEVC-KYLSQKNRVKLIVL-GRTAIPDRESWQSIIMDNEDKQLLKKING 952 +C ++ ++K+ VK +VL GR IP R ++ + +L +KI Sbjct: 3640 VLFITGGTRGLGLLCARHFTEKHGVKKVVLTGREPIPPRHKRSAV-----NTRLKEKIRA 3694 Query: 953 ILAIEALGFTLDYHCVDICDEAQLRRTVEQIRQDHGSINGVFHCAG-VGVGDIEDFGMSG 1011 I +EA G + + + D +E IR+ G I GV HCAG V + + Sbjct: 3695 IEELEAKGVQVAVISLKLSDHDAAAAEIETIRRTMGPIGGVIHCAGSVNSVNPAFIRKTA 3754 Query: 1012 QEFEQRHAVKTYGSWLVYNLTQEFNTGFTLLFSSAVSITGG--RGSLAYTAGNAFVDGLA 1069 ++ ++ K G + +L F +LFSS ++ G Y NA++D A Sbjct: 3755 EDIQEVLEPKVAGLQTLSSLFTNDPLQFFVLFSSVSAVVPALAAGQSDYAMANAYMDYFA 3814 Query: 1070 ETIRLQGKNVMAINWSTWEATA-SRLSLQADKHFFEF-LSTHQALQALDLIIRRGMFRTI 1127 + Q +++I W W+ T + ++ K LS + L LD I+ Sbjct: 3815 AAHQHQ-YPLVSIQWPNWKETGLGEVRTESLKQTGLLGLSNAEGLDLLDRILS------- 3866 Query: 1128 VGKLNVQNKLLELENLWPFRLAGEIKQALFPKTRQ--EERPVRQTSVTVKEPEGYTATHR 1185 EN+ P L + ++ + R +E+ ++T + + R Sbjct: 3867 -------------ENIRPSVLPAIVDRSEWHPDRLLCQEKKQKETEAVINGKAAEKHSDR 3913 Query: 1186 EL--------AQVWADILGLTT--ISVFDSFHQLGGDSIHAAHLHKQWNERHPGTLDVTD 1235 EL ++++D L + + + F G DSI A L +Q N+ LD + Sbjct: 3914 ELLLDTKAWLVKLFSDELKIAPEELETDEPFQDYGVDSIILAQLLQQMNQALKEDLDPSV 3973 Query: 1236 IYRYPTIHEMAGYLDSQRISQPAALNLDSILEGFKGSKYSKEEAKRLLAEWTEHSSVERL 1295 +Y +PTI A +L S QP ++ + + + LL + E+ Sbjct: 3974 LYEHPTIDAFAEWLVSN--GQPLL------------AEREEPDTEMLLPAAVQTVHTEQK 4019 Query: 1296 QPAESDEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLAANQISPE 1355 + A +++ A++G +C+FP AE EQ+W L +G AI P R + Y+A Sbjct: 4020 RDAVTEDIAVVGMSCRFPGAESLEQYWDLLRSGRSAIGSVPAERFGYANQYVA------- 4072 Query: 1356 GHAYCQGGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGGTILSGTR 1415 G ++ +D FDS FF I + + MDP+ +LE + H+G + G Sbjct: 4073 -------GLIDNMDHFDSEFFFIPENDAKAMDPQALAVLEESLKLWCHAGYSREEIKGIE 4125 Query: 1416 TGVYVGKDTTGRNEYNNRVDILDPLK--VTSGSTGILASRIAYYLNLNGPCLVVDTACSS 1473 GVY+G GR+++ +IL + + +G LA+ ++ + +L GP +V+DTACSS Sbjct: 4126 AGVYIG----GRSQHQPDPEILANTRNPIVAGGQNYLAANVSQFFDLRGPSIVLDTACSS 4181 Query: 1474 SLTAICLATQALKQGQIDIAIVAGVSL-----AYLPTQRNSLIDSADEMIRPFDAGANGT 1528 +LT + +A QAL+ G I A+V GVSL A+ Q L++ FD + G Sbjct: 4182 ALTGMNMAVQALRSGDIKAAVVGGVSLLNTDAAHRMFQERGLLNEK-PAFHVFDKRSGGV 4240 Query: 1529 MWGEGAGTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPNAEAQEKVLVAAWKA 1588 + GEG G ++LK +S+A +D IHAVIK + MNN+G + G +APN +AQ+ V+ +A Sbjct: 4241 VLGEGVGMVLLKTVSQAQKDGDTIHAVIKAAAMNNDGRTAGPSAPNMQAQKDVMQSALFK 4300 Query: 1589 ANIDPETISYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAGTVKANIGHLVGASG 1648 + PE ISYIEA+ +G+ + D +E+K I + +R + + G++K NIGH + A G Sbjct: 4301 SGKKPEDISYIEANGSGSAVTDLLELKAIQSVYR--SGQHVPLGIGSIKPNIGHPLCAEG 4358 Query: 1649 MASVIKMIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWSGSAAPRRCGISSFG 1708 +AS IK+++ KHKQ P L P P + + + + +W AA I+ F Sbjct: 4359 IASFIKVVLMLKHKQTVPFLSGDEPMPHFDITKTDFHFHKTAGEW--DAARPSAAINCFA 4416 Query: 1709 FSGTNCHILLE 1719 GTN H++LE Sbjct: 4417 DGGTNAHVILE 4427 Score = 435 bits (1118), Expect = e-119, Method: Compositional matrix adjust. Identities = 262/763 (34%), Positives = 407/763 (53%), Gaps = 56/763 (7%) Query: 1167 VRQTSVTVKEPEGYTATHRELAQVWADILGLT--TISVFDSFHQLGGDSIHAAHLHKQWN 1224 + +T+ + + E A H EL++ AD+L + + + ++F LG DSI K N Sbjct: 2693 MSETAASAEPEEPIEAVHDELSKALADVLYMERHEVDIDEAFIDLGMDSITGLEWIKAVN 2752 Query: 1225 ERHPGTLDVTDIYRYPTIHEMAGYLDSQ-----RISQPAALNLDSILEGFKGSKYSKEEA 1279 +R+ +VT +Y YPTI + A +L +Q R Q + + + + + E Sbjct: 2753 KRYGTDCNVTKVYDYPTIRQFADFLRAQPSVRGRKKQAVPVRPKPLTQQHAPQEKTPAEP 2812 Query: 1280 KRLLAEWTEHSSVERLQPAE--SDEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPE 1337 +RL + + +P + +D AI+G + K+P A + + +W NL AIR P Sbjct: 2813 ERLTIQKEPEPVQAKREPKDEIADAIAIVGMSGKYPDAPELKTYWDNLARAKNAIRDIPL 2872 Query: 1338 SRRKDTDGYLAANQISPEGHAYCQG-GYLEEIDRFDSAFFHISPREGELMDPEQRLLLEN 1396 SR Y A ++ +G YC+ G L++I+ FD FF+ISP E ELMDP+ R+ L+ Sbjct: 2873 SRWDVNKYYDPA--LNKKGKVYCRSIGMLDDIEEFDPLFFNISPSEAELMDPQHRIFLQE 2930 Query: 1397 VYQAAEHSGLGGTILSGTRTGVYVGKDTTGRNEYNNRVDILDPLKVTSGSTG----ILAS 1452 ++A E +G L+G GVY+G NEY +L+ + +TG I A+ Sbjct: 2931 GFKAFEDAGYSSKELNGKNCGVYLG---IMNNEYGM---MLNKHQTGGSATGNSFSIAAA 2984 Query: 1453 RIAYYLNLNGPCLVVDTACSSSLTAICLATQALKQGQIDIAIVAGVSLAYLPTQRNSLID 1512 R+ YYLNL GP + +DTACSSSL LA QAL +ID+A+V GV+L P S+ + Sbjct: 2985 RLPYYLNLKGPAIPIDTACSSSLVGAHLARQALLNHEIDMALVGGVTLYLTPESYISMCE 3044 Query: 1513 ----SADEMIRPFDAGANGTMWGEGAGTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSN 1568 S D + FD ANG + GEGAG ++LKR+ +A D I+ VI GS +N +G +N Sbjct: 3045 AGMLSPDGQCKAFDNSANGFVPGEGAGALVLKRLKDAEADQDHIYGVIIGSGINQDGKTN 3104 Query: 1569 GITAPNAEAQEKVLVAAWKAANIDPETISYIEAHATGTKLGDPIEVKGITNAFRRFTNKR 1628 GITAP+A++Q + ++A NI PE+I+Y E H TGTK GDPIE++ +++ F+ T+++ Sbjct: 3105 GITAPSAKSQMDLERQVYEAHNIHPESITYAEMHGTGTKQGDPIELEALSSVFKEKTDRK 3164 Query: 1629 QFCAAGTVKANIGHLVGASGMASVIKMIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVND 1688 QFCA G+VK+NIGH A+G+ASV K++++ KH+QL P L F PN +F DSP++VN Sbjct: 3165 QFCAIGSVKSNIGHTSAAAGVASVQKVLLSMKHQQLVPTLHFSTPNEHFDFDDSPLFVNT 3224 Query: 1689 RLQDWSGSAAPRRCGISSFGFSGTNCHILLEEPPVFTNPQEAKQDWHILALSAKTAGSLS 1748 L+ W APRR +SSFG+SGTN H+++EE + +I LSAK A + Sbjct: 3225 ELKPWETGGAPRRACVSSFGYSGTNAHLVIEEYQPKDRGSRKPDETNIFVLSAKKAPQVK 3284 Query: 1749 ALIKRYFHMINGTVTLDLQNLCFTANISRGHYEHRIVLLFRTENELRAKFKYLQEA---- 1804 + ++L ++ +T R ++R+ + + EL ++ Sbjct: 3285 TYAESVIEFAKADQNINLSDMAYTLQTGRDAMDYRLAVTAGSREELISRLTDFVNGNTGE 3344 Query: 1805 GILQAADRDQRIYYKASRISYDQEGFDGDGLLEQDKLKLNKLAESLIEEWSVEETLSAVD 1864 GI +A + + KA F+ D L+Q L+ W ++ + Sbjct: 3345 GIYEAHIKTAKKEIKA---------FETDDDLKQ-----------LVRSWFDKKKYA--- 3381 Query: 1865 NLHKIARLYTDGADINWDRLYQGKQHRLTELPAYAYEPVRHWI 1907 KIA L+ G ++WDRLYQG++ R LPAY + +W+ Sbjct: 3382 ---KIAELWAKGLQMDWDRLYQGEKPRRISLPAYPFAKEPYWL 3421 Score = 379 bits (973), Expect = e-102, Method: Compositional matrix adjust. Identities = 312/1071 (29%), Positives = 491/1071 (45%), Gaps = 145/1071 (13%) Query: 920 LIVLGRTAIPDRESWQSIIMDNEDKQLLKKINGILAIEALGFTLDYHCVDICDEAQLRRT 979 LI+ GR+ ++DN K L++++ LG Y D+ ++ +++ Sbjct: 1519 LILTGRS-----------LLDNRKKAQLQELSD------LGAQAVYKQTDMTEKQEVQSL 1561 Query: 980 VEQIRQDHGSINGVFHCAGVGVGDIED-FGMSGQEFEQRHAVKTYGSWLVY--NLTQEFN 1036 I + +G +NG+ H AG I+D + + + E R + S LV+ ++ Sbjct: 1562 TADICRQYGGLNGIIHSAGT----IKDNYILKKHKDEIRDVLAPKVSGLVHLDEAAKDIE 1617 Query: 1037 TGFTLLFSSAVSITGGRGSLAYTAGNAFVDGLAETI-RLQGKN-----VMAINWSTWEAT 1090 F +LFSS G G Y NAF++ +E R + +N ++I W W+ Sbjct: 1618 LDFLILFSSGAGSAGSAGQADYAMANAFMNAFSEKRNRKKARNERYGHTLSICWPLWKDG 1677 Query: 1091 ASRLSLQADKHFFEF-----LSTHQALQALDLIIRRGMFRTIVGKLNVQNKLLELENLWP 1145 + + + + + T +QAL +R G ++++ E Sbjct: 1678 GMTVDAETEAMLTKESGMVPMQTENGIQAL--------YR---GWAANTSQVMVTEGY-- 1724 Query: 1146 FRLAGEIKQALFPKTRQEERPVRQTSVTVKEPEGYTA---------THRELAQVWADI-- 1194 A +I+ F K +++P + + +EP G TA T L QV +++ Sbjct: 1725 ---AAKIRA--FLKKSADDQPDKGSET--EEPVGLTASGENMLAEKTEHFLKQVLSEVTK 1777 Query: 1195 LGLTTISVFDSFHQLGGDSIHAAHLHKQWNERHPGTLDVTDIYRYPTIHEMAGYLDSQRI 1254 L + I G DSI HL + E+ G+L T + Y I + Y Sbjct: 1778 LPVGKIDAKAPMEDYGIDSIMIMHLTGRL-EKSFGSLSKTLFFEYQNIESLTQYF----- 1831 Query: 1255 SQPAALNLDSILE--GFKGSK-----------------YSKEEAKRLLAEWTEHSSVERL 1295 + D++LE G K + + + E K+ A+ + E Sbjct: 1832 ---MKAHRDTLLEVTGMKTEETPAAKPALSEKAKVKPVFKRNEGKKGFAQ-VRPDTRENQ 1887 Query: 1296 QPAESDEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLAANQISPE 1355 Q E ++ AIIG + ++P AE+ ++FW+NL+ G I P R D Y A++ E Sbjct: 1888 QLTEREDIAIIGISGRYPQAENLQEFWKNLSEGTDCITEIPNDRW-DHSLYYDADK-DKE 1945 Query: 1356 GHAYCQ-GGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGGTILS-- 1412 G Y + GG+L+++D+FD FF ISPR+ +LMDP++RL L+ VY+ E +G L+ Sbjct: 1946 GKTYGKWGGFLKDVDKFDPQFFSISPRDAKLMDPQERLFLQCVYETMEDAGYTRKKLTEK 2005 Query: 1413 -----GTRTGVYVGKDTTGRNEYNNRVDILDPLKVTSGSTGILASRIAYYLNLNGPCLVV 1467 G GVYVG Y +G+ +A+R +Y NGP + + Sbjct: 2006 SGDLLGANVGVYVGVMYEEYQLYGAEEQARGKSLALTGNPSSIANRASYVFGFNGPSMAL 2065 Query: 1468 DTACSSSLTAICLATQALKQGQIDIAIVAGVSLAYLPTQ-----RNSLIDSADEMIRPFD 1522 DT CSSSLTAI LA Q+L+ G+ + A GV+++ P + +N + S F Sbjct: 2066 DTMCSSSLTAIHLACQSLRNGECEAAFAGGVNVSVHPNKYLMLGQNRFLSSKGR-CESFG 2124 Query: 1523 AGANGTMWGEGAGTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPNAEAQEKVL 1582 G +G + GEG G ++LK +S+A D I+ +IKG+ +N++G +NG + PN AQ V+ Sbjct: 2125 EGGDGYVPGEGVGAVLLKPLSKAKADGDHIYGLIKGTAVNHDGKTNGYSVPNPNAQAAVI 2184 Query: 1583 VAAWKAANIDPETISYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAGTVKANIGH 1642 A K A DP +SYIEAH TGT LGDPIE+ G+T AF T +QFCA G+ K+NIGH Sbjct: 2185 KQALKDAGTDPRAVSYIEAHGTGTSLGDPIEITGLTKAFSEQTQDKQFCAIGSAKSNIGH 2244 Query: 1643 LVGASGMASVIKMIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWS-------- 1694 A+G+A + K+++ KHKQL P L + NP I+F +P V L++W Sbjct: 2245 CESAAGIAGLTKVLLQMKHKQLAPSLHSRTLNPNIDFLATPFKVQQTLEEWKRPVINENG 2304 Query: 1695 -GSAAPRRCGISSFGFSGTNCHILLEEPPVFTNPQEAKQDWH--ILALSAKTAGSLSALI 1751 PR G+SSFG G N HI++EE + + A H ++ LSAK L Sbjct: 2305 VNKELPRTAGLSSFGAGGVNAHIVIEEYSADEDKETAFAAPHPSMIVLSAKNEQRLQKRA 2364 Query: 1752 KRYFHMINGT--VTLDLQNLCFTANISRGHYEHRIVLLFRTENELRAKFKYLQEAGILQA 1809 KR + DL + +T + R E R+ ++ EL K G ++ Sbjct: 2365 KRLLDALRSGRYREADLSRIAYTLQVGREPMEERLGMIVSNLRELEEKLDEF--TGGKES 2422 Query: 1810 ADRDQRIYYKASRISYDQEGFDGDGLLEQDKLKLNKLAESLIEEWSVEETLSAVDNLHKI 1869 D+ R K ++ D L D + E IE W +E+ +A K+ Sbjct: 2423 IDQLYRGQVKQNK--------DTMALFTAD-----EDMEKTIEAW-LEKGKAA-----KV 2463 Query: 1870 ARLYTDGADINWDRLYQGKQHRLTELPAYAYEPVRHWIGGSARKGSSSPGK 1920 L+ G +NWD+LYQ + + LPAY + R+WI SA P + Sbjct: 2464 LELWVKGLPLNWDKLYQMGRPQKISLPAYPFAKDRYWIDTSADAAVKRPAE 2514 Score = 361 bits (926), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 239/720 (33%), Positives = 364/720 (50%), Gaps = 85/720 (11%) Query: 1230 TLDVTDIYRYPTIHEMAGYLDSQRISQPAALNLDSILEGFKGSKYSKEEAKRLLAEWTEH 1289 TL T ++ Y T E+A +L Q S F S E+ E Sbjct: 360 TLSPTLLFEYTTAAELAAFLTEQYGSH------------FSASPAKMEKQVETQTERRRK 407 Query: 1290 SSVERLQPAESDEYAIIGYACKFPMAEDAEQFWRNLTTGVGAIRPFPESRRKDTDGYLAA 1349 SSV + ++ AIIG A ++P AE+ +FW NL G + PESR D Sbjct: 408 SSV-----PQDEDIAIIGMAGRYPQAENIHEFWENLKEGKNCVTEIPESR---WDWRRFE 459 Query: 1350 NQISPEGHAYCQ-GGYLEEIDRFDSAFFHISPREGELMDPEQRLLLENVYQAAEHSGLGG 1408 N SP G + + GG++++ D FD FF I+PRE E MDP++RL L+ ++ E +G Sbjct: 460 NVKSPSGKSISKWGGFIDDPDCFDPQFFRITPREAETMDPQERLFLQTCWETIEDAGYTP 519 Query: 1409 TILSGTR-------TGVYVG---KDTTGRNEYNNRVDILDPLKVTSGSTGILASRIAYYL 1458 L+ R GV+ G KD T + D + PL + +A+R++Y+ Sbjct: 520 KSLAEARGRNKRQRVGVFAGVMHKDYTLVGAEASSEDHVFPLSLNYAQ---IANRVSYFC 576 Query: 1459 NLNGPCLVVDTACSSSLTAICLATQALKQGQIDIAIVAGVSLAYLPTQ--RNSLID--SA 1514 N +GP + VDT CSSSLTA+ LA +++++G+ + A+ GV+L+ P + L D S Sbjct: 577 NFHGPSMAVDTVCSSSLTAVHLAAESIRRGECESAVAGGVNLSLHPNKYLTYGLWDMFST 636 Query: 1515 DEMIRPFDAGANGTMWGEGAGTIILKRMSEAVQDNHVIHAVIKGSEMNNNGTSNGITAPN 1574 D + F +G + EG G ++LK + EAV+D I+AVIKGS +N+ GT +GI+ P+ Sbjct: 637 DGVCHTFGKDGDGYVPAEGIGAVLLKPLREAVKDGDRIYAVIKGSAVNHVGTVSGISVPS 696 Query: 1575 AEAQEKVLVAAWKAANIDPETISYIEAHATGTKLGDPIEVKGITNAFRRFTNKRQFCAAG 1634 AQ ++ A IDP T+SYIEAH TGT LGDPIEV+G+ AFR++T +QFC+ G Sbjct: 697 PVAQADLIEECLDKAGIDPRTVSYIEAHGTGTSLGDPIEVQGLVKAFRQYTQDKQFCSIG 756 Query: 1635 TVKANIGHLVGASGMASVIKMIMAFKHKQLPPVLQFQNPNPFIEFADSPIYVNDRLQDWS 1694 +VK+NIGH A+G++ + K+ + HK L P L + NP+++F SP YV + W Sbjct: 757 SVKSNIGHAESAAGISGLSKVALQLHHKTLVPSLHSEELNPYLDFEQSPFYVQHHTEAWQ 816 Query: 1695 GSAA---------PRRCGISSFGFSGTNCHILLE----EPPVFTNPQEAKQDWHILALSA 1741 + PRR GISSFG +G+N H++LE E TN + A++ I +SA Sbjct: 817 QPSVTENGNETVYPRRAGISSFGATGSNVHLILEEFIPEESHGTNAEPAEEQTFIFPVSA 876 Query: 1742 KTAGSLSALIKRYFHMINGTVTLDLQNLCFTANISRGHYEHRIVLLFRTENELRAKFKYL 1801 + L + + I+ L L++ +T I R E R+V + +L+ + + Sbjct: 877 RNEERLKEYVAKLSAFIHP--GLPLEDAAYTLQIGREQMEERVVFTAQNMTQLKERLEGF 934 Query: 1802 QEAGILQAADRDQRIYYKASRISYDQEGFDGDGLLEQDKLKLNKLAESLIEEWSVEETLS 1861 + R++ DK K +LA LI +W LS Sbjct: 935 LAGKTVSGCWRNR-----------------------ADKSKQAELAPDLIHKW-----LS 966 Query: 1862 AVDNLHKIARLYTDGADINWDRLY-QGKQHRLTELPAYAYEPVRHWIGGSARKGSSSPGK 1920 + +L IA + G ++W LY + K +R++ LP Y +E +R+W+ A K S P K Sbjct: 967 S-GSLEMIAEKWAGGGTMDWKLLYGENKPNRIS-LPTYPFEKIRYWV-PKAEKRESLPQK 1023 Score = 343 bits (881), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 221/642 (34%), Positives = 339/642 (52%), Gaps = 61/642 (9%) Query: 37 RSEEIAVVGISGRFPKADRVEQFWDNLCSGRDCLDTFPEDRLHDGQALAPERHLAGGSL- 95 + E+IA++G++GR+P+A+ + +FW+NL G++C+ PE R D + + +G S+ Sbjct: 412 QDEDIAIIGMAGRYPQAENIHEFWENLKEGKNCVTEIPESRW-DWRRFENVKSPSGKSIS 470 Query: 96 KQGGYLDEISFFDAEMFRISPKEALSMEPYQRIMLEVAYDTLVNAGYETQDILGSK---- 151 K GG++D+ FD + FRI+P+EA +M+P +R+ L+ ++T+ +AGY + + ++ Sbjct: 471 KWGGFIDDPDCFDPQFFRITPREAETMDPQERLFLQTCWETIEDAGYTPKSLAEARGRNK 530 Query: 152 ---TGVFIGRDH--VTGIEYRNYAAPDIFRLTGGWPGILASRISYVYNLKGPSVVFDTSC 206 GVF G H T + + +F L+ + I A+R+SY N GPS+ DT C Sbjct: 531 RQRVGVFAGVMHKDYTLVGAEASSEDHVFPLSLNYAQI-ANRVSYFCNFHGPSMAVDTVC 589 Query: 207 SSGLVGLHFACESLRRNECDMAFVGGISGLFYFPPVKEDGSLDQVESAEEKIRAFDKAAE 266 SS L +H A ES+RR EC+ A GG++ L P L + S + F K + Sbjct: 590 SSSLTAVHLAAESIRRGECESAVAGGVN-LSLHPNKYLTYGLWDMFSTDGVCHTFGKDGD 648 Query: 267 GTVWGEGCGGLLLKPLSKAVADKDVIYAVIKGSGINNNGLSKGITAPNGEAQEELLKKVW 326 G V EG G +LLKPL +AV D D IYAVIKGS +N+ G GI+ P+ AQ +L+++ Sbjct: 649 GYVPAEGIGAVLLKPLREAVKDGDRIYAVIKGSAVNHVGTVSGISVPSPVAQADLIEECL 708 Query: 327 KQAQINPETIRYIETHGTGTILGDTIELNSIINAFQAFTSKKQFCGVGSVKTNIGHLVGA 386 +A I+P T+ YIE HGTGT LGD IE+ ++ AF+ +T KQFC +GSVK+NIGH A Sbjct: 709 DKAGIDPRTVSYIEAHGTGTSLGDPIEVQGLVKAFRQYTQDKQFCSIGSVKSNIGHAESA 768 Query: 387 SGIVSLIKAVLMLKHGEIPASLHFQTPSPYINLADSALFIN------DQRSKLEKGN--- 437 +GI L K L L H + SLH + +PY++ S ++ Q S E GN Sbjct: 769 AGISGLSKVALQLHHKTLVPSLHSEELNPYLDFEQSPFYVQHHTEAWQQPSVTENGNETV 828 Query: 438 HPVRIGINSFGFSGTNCHVLLEE-PPVPVYDNN---AENNVFLLTLSARSSQKLVEAAQS 493 +P R GI+SFG +G+N H++LEE P + N AE F+ +SAR+ ++L E Sbjct: 829 YPRRAGISSFGATGSNVHLILEEFIPEESHGTNAEPAEEQTFIFPVSARNEERLKEYVAK 888 Query: 494 LQRFLLTNRSVNLADMCCTASQFRNHFANRLAITFSSYEDLLAKLKIIRETKELS-LWSS 552 L F+ + + L D T R R+ T + L +L+ K +S W + Sbjct: 889 LSAFI--HPGLPLEDAAYTLQIGREQMEERVVFTAQNMTQLKERLEGFLAGKTVSGCWRN 946 Query: 553 HPGISFQLHEVVADTKSQIEAWEIREGEKIALDKTANEAIRELLQKKAGSEMLWEQAARF 612 AD Q E +A D L+ K S L E A Sbjct: 947 R-----------ADKSKQAE---------LAPD---------LIHKWLSSGSL-EMIAEK 976 Query: 613 YIKGASMDWRPLYPGCR--KLAMPGNVLERTKYWPAEAKRGE 652 + G +MDW+ LY + ++++P E+ +YW +A++ E Sbjct: 977 WAGGGTMDWKLLYGENKPNRISLPTYPFEKIRYWVPKAEKRE 1018 Score = 343 bits (881), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 217/646 (33%), Positives = 337/646 (52%), Gaps = 78/646 (12%) Query: 39 EEIAVVGISGRFPKADRVEQFWDNLCSGRDCLDTFPEDRLHDGQALAPERHLAGGSL-KQ 97 E+IA++GISGR+P+A+ +++FW NL G DC+ P DR ++ G + K Sbjct: 1893 EDIAIIGISGRYPQAENLQEFWKNLSEGTDCITEIPNDRWDHSLYYDADKDKEGKTYGKW 1952 Query: 98 GGYLDEISFFDAEMFRISPKEALSMEPYQRIMLEVAYDTLVNAGY-------ETQDILGS 150 GG+L ++ FD + F ISP++A M+P +R+ L+ Y+T+ +AGY ++ D+LG+ Sbjct: 1953 GGFLKDVDKFDPQFFSISPRDAKLMDPQERLFLQCVYETMEDAGYTRKKLTEKSGDLLGA 2012 Query: 151 KTGVFIGRDHVTGIEYRNYAAPDIFR-----LTGGWPGILASRISYVYNLKGPSVVFDTS 205 GV++G V EY+ Y A + R LTG P +A+R SYV+ GPS+ DT Sbjct: 2013 NVGVYVG---VMYEEYQLYGAEEQARGKSLALTGN-PSSIANRASYVFGFNGPSMALDTM 2068 Query: 206 CSSGLVGLHFACESLRRNECDMAFVGGISGLFYFPPVKEDGSLDQVESAEEKIRAFDKAA 265 CSS L +H AC+SLR EC+ AF GG++ + P ++ S++ + +F + Sbjct: 2069 CSSSLTAIHLACQSLRNGECEAAFAGGVN-VSVHPNKYLMLGQNRFLSSKGRCESFGEGG 2127 Query: 266 EGTVWGEGCGGLLLKPLSKAVADKDVIYAVIKGSGINNNGLSKGITAPNGEAQEELLKKV 325 +G V GEG G +LLKPLSKA AD D IY +IKG+ +N++G + G + PN AQ ++K+ Sbjct: 2128 DGYVPGEGVGAVLLKPLSKAKADGDHIYGLIKGTAVNHDGKTNGYSVPNPNAQAAVIKQA 2187 Query: 326 WKQAQINPETIRYIETHGTGTILGDTIELNSIINAFQAFTSKKQFCGVGSVKTNIGHLVG 385 K A +P + YIE HGTGT LGD IE+ + AF T KQFC +GS K+NIGH Sbjct: 2188 LKDAGTDPRAVSYIEAHGTGTSLGDPIEITGLTKAFSEQTQDKQFCAIGSAKSNIGHCES 2247 Query: 386 ASGIVSLIKAVLMLKHGEIPASLHFQTPSPYINLADSALFINDQRSKLEKGNHPV----- 440 A+GI L K +L +KH ++ SLH +T +P I+ + + + LE+ PV Sbjct: 2248 AAGIAGLTKVLLQMKHKQLAPSLHSRTLNPNIDFLATPFKV---QQTLEEWKRPVINENG 2304 Query: 441 -------RIGINSFGFSGTNCHVLLEEPPVPVYDNNAEN-----NVFLLTLSARSSQKLV 488 G++SFG G N H+++EE D + E + ++ LSA++ Q+L Sbjct: 2305 VNKELPRTAGLSSFGAGGVNAHIVIEEYSA---DEDKETAFAAPHPSMIVLSAKNEQRLQ 2361 Query: 489 EAAQSLQRFLLTN--RSVNLADMCCTASQFRNHFANRLAITFSSYEDLLAKLKIIRETKE 546 + A+ L L + R +L+ + T R RL + S+ +L KL KE Sbjct: 2362 KRAKRLLDALRSGRYREADLSRIAYTLQVGREPMEERLGMIVSNLRELEEKLDEFTGGKE 2421 Query: 547 LSLWSSHPGISFQLHEVVA------DTKSQIEAWEIREGEKIALDKTANEAIRELLQKKA 600 S+ + G Q + +A D + IEAW L+K Sbjct: 2422 -SIDQLYRGQVKQNKDTMALFTADEDMEKTIEAW---------------------LEKGK 2459 Query: 601 GSEMLWEQAARFYIKGASMDWRPLYPGCR--KLAMPGNVLERTKYW 644 +++L ++KG ++W LY R K+++P + +YW Sbjct: 2460 AAKVL-----ELWVKGLPLNWDKLYQMGRPQKISLPAYPFAKDRYW 2500 Score = 140 bits (353), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 119/446 (26%), Positives = 203/446 (45%), Gaps = 48/446 (10%) Query: 2080 GMAKVIPQEYPQFKCRCIDIDSATAPATVWKEIC----SGKGDFQVAYRDNTRYLEHFGE 2135 G+ +++ EY R +D D T T+ K+I + + ++ R+ RY F E Sbjct: 3562 GLYRMLQNEYQNVTSRHMDADKDTDQQTLAKQIADEFSADCTEPEICRRNGQRYRALFRE 3621 Query: 2136 -RRLEAAEAGGVSLKENGVYVVTGGLGGIGLAVAQYLSGKQRVH-LCLLNRRTLPPGPSQ 2193 + AE E+ V +TGG G+GL A++ + K V + L R +PP + Sbjct: 3622 IPSGKRAEHKPAPFPEDHVLFITGGTRGLGLLCARHFTEKHGVKKVVLTGREPIPPRHKR 3681 Query: 2194 S----------QRIRQIEANGSDVDLYSVDISAPNELQGVLQAIRTKYGQINGLFHCAGI 2243 S + I ++EA G V + S+ +S + ++ IR G I G+ HCAG Sbjct: 3682 SAVNTRLKEKIRAIEELEAKGVQVAVISLKLSDHDAAAAEIETIRRTMGPIGGVIHCAGS 3741 Query: 2244 AGE--GLLINKGKPEIKRVLDAKVTGTWLLDQYTAQDHLDYFVLFSSVTSLLGGM--GQA 2299 I K +I+ VL+ KV G L D L +FVLFSSV++++ + GQ+ Sbjct: 3742 VNSVNPAFIRKTAEDIQEVLEPKVAGLQTLSSLFTNDPLQFFVLFSSVSAVVPALAAGQS 3801 Query: 2300 DYTAANAYLDGFSDYRQANNRRSVTINWPAWKEVGMTLKYDIQEGRSPFLGLTEEQGISI 2359 DY ANAY+D F+ Q + V+I WP WKE G+ ++ LGL+ +G+ + Sbjct: 3802 DYAMANAYMDYFAAAHQ-HQYPLVSIQWPNWKETGLGEVRTESLKQTGLLGLSNAEGLDL 3860 Query: 2360 LDAVLQRKLSRIIAGEINERYFQNGDPSLPFAVPPQMISRGTGAFNPQEKVIADEPILPI 2419 LD +L + + I +R + D L QEK + + Sbjct: 3861 LDRILSENIRPSVLPAIVDRSEWHPDRLLC-----------------QEK--KQKETEAV 3901 Query: 2420 LKGRYDHSYNSYEISL------AAMWQKVLGVA--EVNVHLPFQETGGNSILATSLVKEI 2471 + G+ ++ E+ L ++ L +A E+ PFQ+ G +SI+ L++++ Sbjct: 3902 INGKAAEKHSDRELLLDTKAWLVKLFSDELKIAPEELETDEPFQDYGVDSIILAQLLQQM 3961 Query: 2472 DGVYPGCVNIATLFAYPSIAKMAEYL 2497 + ++ + L+ +P+I AE+L Sbjct: 3962 NQALKEDLDPSVLYEHPTIDAFAEWL 3987 Score = 104 bits (259), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 111/434 (25%), Positives = 195/434 (44%), Gaps = 31/434 (7%) Query: 2078 LFGMAKVIPQEYPQFKCRCIDIDSATAPATV---WKEICSGKGDFQVAYRDNTRYLEHFG 2134 L G+ K E P + I+ + T+ KE + D + Y + RY + Sbjct: 1415 LTGLLKTAALENPNLTGQLIETEPDVKADTLSRYVKECSAHPDDKHIRYENGRRYTAQWQ 1474 Query: 2135 ERRLEAAEAGGVSLKENGVYVVTGGLGGIGLAVAQYLSGKQRVHLCLLNRRTLPPGPSQS 2194 E LE A K+ GVY++TGG GG+G A+ ++ + + +L R+L ++ Sbjct: 1475 ETGLEQFGAEK-PWKDKGVYLITGGAGGLGFLFAREIARHAKDAVLILTGRSLLDNRKKA 1533 Query: 2195 QRIRQIEANGSDVDLYSVDISAPNELQGVLQAIRTKYGQINGLFHCAGIAGEGLLINKGK 2254 Q ++++ G+ D++ E+Q + I +YG +NG+ H AG + ++ K K Sbjct: 1534 Q-LQELSDLGAQAVYKQTDMTEKQEVQSLTADICRQYGGLNGIIHSAGTIKDNYILKKHK 1592 Query: 2255 PEIKRVLDAKVTGTWLLDQYTAQDHLDYFVLFSSVTSLLGGMGQADYTAANAYLDGFSDY 2314 EI+ VL KV+G LD+ LD+ +LFSS G GQADY ANA+++ FS+ Sbjct: 1593 DEIRDVLAPKVSGLVHLDEAAKDIELDFLILFSSGAGSAGSAGQADYAMANAFMNAFSEK 1652 Query: 2315 R---QANNRR---SVTINWPAWKEVGMTLKYDIQ---EGRSPFLGLTEEQGISILDAVLQ 2365 R +A N R +++I WP WK+ GMT+ + + S + + E GI L Sbjct: 1653 RNRKKARNERYGHTLSICWPLWKDGGMTVDAETEAMLTKESGMVPMQTENGIQALYRGWA 1712 Query: 2366 RKLSRIIAGEINERYFQNGDPSLPFAVPPQMISRGTGAFNPQEKVIADEPILPILKGRYD 2425 S+++ E +A + + + P + +EP+ G + Sbjct: 1713 ANTSQVMVTE-------------GYAAKIRAFLKKSADDQPDKGSETEEPVGLTASGE-N 1758 Query: 2426 HSYNSYEISLAAMWQKV--LGVAEVNVHLPFQETGGNSILATSLVKEIDGVYPGCVNIAT 2483 E L + +V L V +++ P ++ G +SI+ L ++ + G ++ Sbjct: 1759 MLAEKTEHFLKQVLSEVTKLPVGKIDAKAPMEDYGIDSIMIMHLTGRLEKSF-GSLSKTL 1817 Query: 2484 LFAYPSIAKMAEYL 2497 F Y +I + +Y Sbjct: 1818 FFEYQNIESLTQYF 1831 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.399 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 15,458,265,942 Number of extensions: 676778724 Number of successful extensions: 1862202 Number of sequences better than 1.0e-05: 10335 Number of HSP's gapped: 1789237 Number of HSP's successfully gapped: 26548 Length of query: 2551 Length of database: 3,060,696,203 Length adjustment: 153 Effective length of query: 2398 Effective length of database: 1,619,280,908 Effective search space: 3883035617384 Effective search space used: 3883035617384 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 140 (58.5 bits)