BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0015.p (2806 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I5H8.1 B8I5H8_CLOCE Amino acid adenylation domain protein 830 0.0 O30409.1 TYCC_BREPA Tyrocidine synthetase 3 ATP-dependent aspara... 679 0.0 C0ZDA6.1 C0ZDA6_BREBN Tyrocidine synthetase II EC=5.1.1.11 676 0.0 C0ZDA7.1 C0ZDA7_BREBN Tyrocidine synthetase III 673 0.0 O30981.1 O30981_BACSU Fengycin synthetase FenE 665 0.0 >B8I5H8.1 B8I5H8_CLOCE Amino acid adenylation domain protein Length = 4196 Score = 830 bits (2145), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/1186 (36%), Positives = 689/1186 (58%), Gaps = 43/1186 (3%) Query: 1618 PVTRKSQGKRPELPVAYVPAGTDTEK---------KLCAIYENHLGFQPIGIEDDFFELS 1668 P+T + R LP + T+TE+ +L I++ L +G+ ++FF+L Sbjct: 1787 PLTPNGKINRKALPEPDRISLTETERQKPQNELEERLADIFKEILNTDILGVTENFFDLG 1846 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNP-KSHY 1727 G+SL A+ + I K+F+ ++LT+ F TI+ +A +I + V P + +Y Sbjct: 1847 GNSLSAMILSLRINKEFNTEVSLTNIFTMSTIRQLANYINQKENKAVYDVIEVQPEREYY 1906 Query: 1728 PTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAE 1787 P S AQ+R+F L + YN +VL+EGN++ G++E +++ RHE LRTSF Sbjct: 1907 PMSQAQRRMFILNQIEDTQTSYNIYGAVLIEGNLDIGKLESAAKELLQRHEILRTSFEVV 1966 Query: 1788 NGEIVQIIHPHVDFKL---IRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQS 1844 NGE Q++H V+F L V+ + ++ + FI+PFDL++A LIR+GL+ E++ Sbjct: 1967 NGEPCQLVHKDVEFGLEIIKNNDVESEDLDNKITGFIRPFDLSKALLIRIGLIPLEEKRH 2026 Query: 1845 ILVVDMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKET 1904 ++++DMHHII+DGTSVN+L+ D LY GK LPP+ IQYKD++ WQ + SE + +E+ Sbjct: 2027 VVIMDMHHIISDGTSVNILLKDLFALYKGKDLPPVKIQYKDFSVWQNKLLKSEIMKGQES 2086 Query: 1905 YWLEKLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMX 1964 YWLE G +PVL LP DYPRP + F+G E+D ++ +I+ + E T FM + Sbjct: 2087 YWLETFKGEIPVLNLPIDYPRPPIMDFKGEVYEFEIDEFTTSKIRNLASESNTTMFMILL 2146 Query: 1965 XXXXXXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAF 2024 +G+ DI++G+P AGR H D+Q VGMF+N++ LR+ P + + F+ F Sbjct: 2147 SSYNVLLSKLTGQDDIIVGVPSAGRKHADIQNTVGMFINTIALRSNPG----KNRTFMDF 2202 Query: 2025 LQEVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHD 2084 LQEVR + LEA E QDFQ E+++D L KRD R L+DT+ N+ +M + S D Sbjct: 2203 LQEVRKNSLEAFEYQDFQFELLLDMLGIKRDLSRNPLFDTVLNFYNMNDSDNNYMSDETD 2262 Query: 2085 MKLSPYPMTSKTTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPE 2144 L PY + + K D+ ++ E + C YRT LFK T++YI EY +L+ I + Sbjct: 2263 FNLYPYEVKNNVAKFDIVLYASETDERLKFYCNYRTSLFKSSTIEYIMGEYVKLLGIIAD 2322 Query: 2145 QAGRTIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPAEN--------LVQRFEKQVAA 2196 + + I + +F + I N P+ + N P ++ LV+ EKQV Sbjct: 2323 EPEKLIRDYYIFSRESIV----NKRNPIVLKN---NGPEKSGTIKEHKTLVESIEKQVEE 2375 Query: 2197 YPAHTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGA 2256 + TAVK + + Y +LN+ AN IA I LK+ +S +R V LLF + +M+ + G Sbjct: 2376 HRESTAVKTHDRLVTYGELNDSANNIANII--LKKSKSNDR-VTLLFEHGADMIIGILGV 2432 Query: 2257 IKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEG 2316 +K G +VPLD + P +RL+ + D+ A +++T+ +N A EL ++ KV ++N + Sbjct: 2433 LKTGRSYVPLDPAYPEERLVDIFKDSGAEILVTNDKNLKYAEELVHILNRKVYLINIDKV 2492 Query: 2317 LSGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRM 2376 A NP + + +QTA+ILYTSG++G PKGV+QS++NI + + L ++H DR+ Sbjct: 2493 DLISPANNPKIAIEPEQTAYILYTSGTTGKPKGVMQSHKNIMELVGNYAEELLISHADRL 2552 Query: 2377 ALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRF 2436 L T+YSH + +DI ++LLNGA ++ DLK SI+ +S+W+ I++ H+VPS++R+ Sbjct: 2553 GLTTSYSHTVAAIDIFSALLNGAGIYPYDLKNKGSIENMSNWIEENSISILHTVPSIYRY 2612 Query: 2437 LMKNLPGDVKLPSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMVISFYTLD 2496 +K++ ++ R+++LGGEVV +D E YK ++ C+FVN G SE++V +FY +D Sbjct: 2613 FIKSIDKTKRISDTRLIILGGEVVYSSDIEEYKLLFSDDCIFVNLFGASEILVATFYLVD 2672 Query: 2497 KGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERV 2556 K ++VN +P GY ++G+ ++++ + + AGI+E G+LVY S YLS GYWN T Sbjct: 2673 KNTQVNTRTVPIGYELEGVSIQLLNDDNKAAGIYECGELVYHSHYLSQGYWNLDEKTNHQ 2732 Query: 2557 FASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQ 2616 F P++G Y+SGD RLLP+G +E+ GR D Q+KIRG R++L EIES + + I+ Sbjct: 2733 FERNPETGEVIAYKSGDLARLLPSGTIEHLGRKDTQVKIRGMRIELTEIESVVGGLKGIR 2792 Query: 2617 QSIVTATLDHEGEQAIAAYYVL--KEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTG 2674 + E I +YV +E K +L+ +LP Y+IP ++ P T Sbjct: 2793 ECAAIVLEKPNQENTIVVFYVPENEEVIENKQFKLMLKSKLPEYMIPSLLYPVESIPHTP 2852 Query: 2675 PNKVDRNALPAPDAIPSNDLRHE--YVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIG 2732 KVDR AL +I + D++ E Y PP N++E + +W E+L I IGV++ FFE+G Sbjct: 2853 NGKVDRKAL----SIKNVDVKEEAAYEPPTNQVEERMTEIWSEILEIGKIGVNENFFELG 2908 Query: 2733 GHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFLKDKHNHN 2778 GHSL + + + K ++ V++G++F YPTI LA + D N Sbjct: 2909 GHSLKATSLVSRIHKAFQVEVKLGEVFSYPTIRELAKLITDSVKEN 2954 Score = 613 bits (1580), Expect = e-172, Method: Compositional matrix adjust. Identities = 361/1180 (30%), Positives = 636/1180 (53%), Gaps = 42/1180 (3%) Query: 1609 GQPGKNG-PEPVTRKSQGKRPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFEL 1667 G+ KN P P + + KR E Y+ +TE+ L I+++ + +GI+DDF+EL Sbjct: 749 GKLDKNALPNP--KDTLKKRTE----YIEPRNNTEQSLVPIWQDVFQIEKLGIKDDFYEL 802 Query: 1668 SGDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHY 1727 G SLKAI + S I K + + ++ I+ +A++I + S+A + PV + +Y Sbjct: 803 GGHSLKAITLSSRIFKDLNVEVPISILLSTPNIEGIAKYIDSKSKALYINLKPVEERDYY 862 Query: 1728 PTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAE 1787 S AQKR F L YN + ++EG+++ +E++F+++INRH++ RT F Sbjct: 863 CLSSAQKRFFILNQFDEVNTSYNMPAAFIIEGDLDISHMEKIFSELINRHDAFRTVFEF- 921 Query: 1788 NGEI-VQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSIL 1846 NG++ VQ I +FK I + + +A+ FI+PFDLA+APL RVGL++ + + ++ Sbjct: 922 NGQVPVQRITASAEFK-IEQIQPDYNLLKAIGSFIKPFDLAKAPLFRVGLIRLADSKHLM 980 Query: 1847 VVDMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYW 1906 ++DMHHIIADG S+N+++ +F LY GK LP L QYKD++EWQ S +E YW Sbjct: 981 LIDMHHIIADGLSINIIIKEFLQLYEGKELPELKFQYKDFSEWQNKLFESGEILKQEKYW 1040 Query: 1907 LEKLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXX 1966 + K +G +PVL LPTD+PRP+ S++G ++ +D +++ ++ + T+FM + Sbjct: 1041 INKFSGEIPVLNLPTDFPRPSVKSYEGDKVEFNIDNNIKRKLELMAEGTKATFFMVLLTA 1100 Query: 1967 XXXXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQ 2026 SG+ DI+IG P +GR + D++ +VG+FVN+L +RN + + F FL+ Sbjct: 1101 YNVLLSKYSGQEDIIIGTPVSGRTYSDLENIVGVFVNTLAIRN----TIDSESTFREFLE 1156 Query: 2027 EVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMK 2086 V+ S LEA +NQD+Q E +VD L+ RD R ++DT+F++ + + E L ++K Sbjct: 1157 RVKESCLEAYDNQDYQFEELVDNLNLHRDTSRNPVFDTMFSFNN-----DIEEIELENLK 1211 Query: 2087 LSPYPMTSKTTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQA 2146 L PY +++ TK DL+++ ++ I+ Y T LFKRET + I + ++++ + Sbjct: 1212 LFPYDISNGQTKFDLSLNAFDDGQVIHFSLEYCTKLFKRETAEKITRHFTKILDQVVLNP 1271 Query: 2147 GRTIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQRFEKQVAAYPAHTAVKYR 2206 + ++ + + +++ R F+ + Q FE+QV P + A+ + Sbjct: 1272 EIRLSDIDILTTEEKRHLLFDLNSTKREYPFY-----SGIHQLFEEQVQKTPHNIALIFE 1326 Query: 2207 EESLNYRQLNEQANRIARRIWELKEQESVERPVA-LLFGNTIEMVAALAGAIKAGIPFVP 2265 + L Y +LNE++NRIA W L E+ E V ++ ++E+V + +KAG ++P Sbjct: 1327 GKQLTYHELNEKSNRIA---WYLIEKGVREDSVVGIMVERSMELVIGIMAILKAGGAYLP 1383 Query: 2266 LDRSAPLQRLIHMVNDAQATLILTDSE-NESIARELAERVHAKVTIVNTAEGLSGVSAE- 2323 +D P +R+ ++N++ +++LT + +E + E E + + + N ++ ++ E Sbjct: 1384 IDPDYPKERIDFLINNSNTSMLLTGKKISEDMYLENTETIAVREVLDNNNLPVTNLNLEY 1443 Query: 2324 NPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYS 2383 NP ++ +++YTSGS+G PKGV+ + + F + +D ++ S Sbjct: 1444 NP------ERLMYVIYTSGSTGNPKGVMVKSHSFVNLLNWFVREFDIGEKDCNLIIAPAS 1497 Query: 2384 HAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLM--KNL 2441 + + ++L+ G L + L +R+S +N E +T+ + PS F L+ Sbjct: 1498 FDLAQKNFFSTLVTGGCLCIFSPGL-YDYERMSEVINKEHVTMINCTPSAFYPLIDFNAD 1556 Query: 2442 PGDVKLPSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELM-VISFYTLDKGSE 2500 G ++L SL V LGGE + ++K+ A VN G +E + SFY +D Sbjct: 1557 SGFLRLQSLSRVFLGGEPINMGKLLPWRKSMAYSADIVNTYGPTECTDIASFYRIDNNII 1616 Query: 2501 VNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASG 2560 +P G +D + + I+ ++ + VG+L L+ GY+N G+T+ F Sbjct: 1617 EQETAVPIGKPIDNVQIYILDKNQKLVPQGMVGELCIGGIGLTRGYYNDPGLTKERFIEC 1676 Query: 2561 PDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIV 2620 +++YR+GD + G +E+ GR D Q+KIRGYR+++ EIE+++ P I++++ Sbjct: 1677 EGISGRKVYRTGDLAKWTQEGNIEFLGRVDNQVKIRGYRIEMGEIEASILSHPAIREAVA 1736 Query: 2621 TATLDHEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDR 2680 A D G + I AY V + ++ L++ LP Y+IP +++++ P+T K++R Sbjct: 1737 IAKEDSTGGKYICAYIVSDTGLSITELRDYLQKSLPGYMIPSRFVQIEKMPLTPNGKINR 1796 Query: 2681 NALPAPDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQ 2740 ALP PD I + + P+NE+E LA ++ E+L +GV + FF++GG+SL M Sbjct: 1797 KALPEPDRISLTETERQ--KPQNELEERLADIFKEILNTDILGVTENFFDLGGNSLSAMI 1854 Query: 2741 VQNNLEKELKLTVEMGDLFKYPTISSLATFLKDKHNHNDY 2780 + + KE V + ++F TI LA ++ K N Y Sbjct: 1855 LSLRINKEFNTEVSLTNIFTMSTIRQLANYINQKENKAVY 1894 Score = 589 bits (1519), Expect = e-165, Method: Compositional matrix adjust. Identities = 367/1163 (31%), Positives = 611/1163 (52%), Gaps = 69/1163 (5%) Query: 1633 AYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAIHVISSIRKQFDCNLTLT 1692 AY P E+++ I+ L IG+ ++FFEL G SLKA ++S I K F + L Sbjct: 2873 AYEPPTNQVEERMTEIWSEILEIGKIGVNENFFELGGHSLKATSLVSRIHKAFQVEVKLG 2932 Query: 1693 DFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLAQKRIFFLQGLMPDTVGYNES 1752 + F TI+ +A+ I ++ + N + I PV K +YP S AQKR+F L + YN Sbjct: 2933 EVFSYPTIRELAKLITDSVKENYKPIKPVGKKENYPASSAQKRLFILNQIEDAKTTYNIP 2992 Query: 1753 TSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIVQIIHPHVDFKLIRTAVKE-- 1810 + ++ G ++ ++E F +++ RHESLRT+F NGE+VQI+ +D K+ V++ Sbjct: 2993 GAAIINGVLDREKVERAFNKLVQRHESLRTAFSIVNGELVQIVKDKIDLKVTFLEVEKVP 3052 Query: 1811 ---QGIEEAVE---RFIQPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIADGTSVNLLV 1864 + +E +E F++PFDL++APL+RV L++ + IL+ D+HHII+D TS+ +LV Sbjct: 3053 GTKESTDEIIEIFKEFVKPFDLSKAPLLRVALIKIDLDKHILLYDIHHIISDATSIGILV 3112 Query: 1865 NDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYP 1924 N+F D Y GK L L +QYK+++ WQ + ++ + +E +WL+ G LP+L LPTDY Sbjct: 3113 NEFIDAYCGKELRELKVQYKEFSTWQNELLKTDIIKKQEEFWLDYFKGELPLLNLPTDYT 3172 Query: 1925 RPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGI 1984 RP+ SF+G ++ ELD + +KK + + T FM + SG+SDI++G Sbjct: 3173 RPSTQSFEGDTLSFELDGELLQLLKKTANKTGTTLFMLLLSAYNILLSKYSGQSDIIVGS 3232 Query: 1985 PQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIE 2044 P AGR +++ +VGMF N++ +RN + K FL +V+ + ++ ENQ +Q + Sbjct: 3233 PIAGRVQTELENVVGMFANTIAMRNN----VDGNKTLGMFLSDVKENTIQVYENQLYQFD 3288 Query: 2045 MIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLSPYPMTSKTTKADLNIH 2104 +++++L+ RD R L+DT+F Q+M N +E L M PY M ++T+K D+ + Sbjct: 3289 VLINKLNLNRDLSRNPLFDTMFTMQNM-NISERVVDGLSIM---PYGMDNRTSKFDITVE 3344 Query: 2105 LYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDIPPA 2164 + E + Y T LF++ET+ + E + +I+A+ I E+ + + Sbjct: 3345 VKEDDGKLIFIMEYCTRLFRKETIVRMAEHLKNIIKALTLNLDTPITEVSLLSDTE---- 3400 Query: 2165 GGNVSPPVRFQAFHYND-----PAENLVQR-FEKQVAAYPAHTAVKYREESLNYRQLNEQ 2218 R + +N+ P + FE+QV P A E + Y LN + Sbjct: 3401 -------KRQILYEFNNTKADYPKNKTIHELFEEQVIQNPDFIAAICNSEEITYMDLNTR 3453 Query: 2219 ANRIARRIWELKEQESVERP--VALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLI 2276 ANRIA E+ V+R VA+L ++EM+AA+ G +K+G ++PLD P +RL Sbjct: 3454 ANRIA----EVLRDRGVQRDSLVAILVSRSLEMLAAILGVLKSGAAYLPLDPEYPEERLR 3509 Query: 2277 HMVNDAQATLILTDSE-NESIARELAERVHAKVTIVNTAEG-LSGVSAENPSVCPDGDQT 2334 ++ D+ A ++L +S N I+ H +V ++ A G ++ S EN + Sbjct: 3510 FILEDSNAHILLANSNLNSGIS------FHGEV--IDLAHGSINQKSGENLPNINNPKDL 3561 Query: 2335 AFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIGILDILAS 2394 A++LYTSGS+G PKGV+ S+ + ++ T + + + LTT S I +L+ L Sbjct: 3562 AYVLYTSGSTGKPKGVMISHDAVCNFMTGVTDKIRIEKGSSILALTTISFDIFVLETLLP 3621 Query: 2395 LLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKLPSLRMVL 2454 L +G + + D + L + + I + PS + LM L S++ V+ Sbjct: 3622 LCHGLKVVIADEDHQKDPRMLRGLITGKNIDMLQMTPSTLQILMNELKNLSCFNSVKQVM 3681 Query: 2455 LGG----EVVTRADFELYKKNCAEHCLFVNFLGCSELMVIS-FYTLDKGSEVNHARLPAG 2509 +GG E + R ++YK N G +E V S L K S V+ G Sbjct: 3682 IGGEAFPETLLRELRKVYKGK------IYNMYGPTETTVWSAIKDLTKNSCVS-----IG 3730 Query: 2510 YAVDGIDVRIV-GESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKRL 2568 + + I+ G++ + G+ G++ + L+ GY N++ +T+ F S KRL Sbjct: 3731 GPIANTQILIMNGDNLQPIGV--AGEVCIGGDSLARGYLNRSELTKEKFVSSELVPGKRL 3788 Query: 2569 YRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHEG 2628 Y++GD + +P+G + + GR D Q+KIRGYR++L+EIE + I + +V A D Sbjct: 3789 YKTGDLAKWMPDGSIAFMGRIDNQVKIRGYRIELDEIEKCILKYNLINECVVIAQEDEFS 3848 Query: 2629 EQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAPDA 2688 + + YYV E +I++ + LP Y+IP ++ L P+T KVDR ALPA Sbjct: 3849 NKQLICYYVSSEEITVSEIMQHIGRDLPDYMIPGIYVRLASIPLTPNGKVDRRALPAAGT 3908 Query: 2689 IPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKE 2748 N + EY +E+E +A +W +L IG++D FF++GG+S+LL+++ LEK Sbjct: 3909 ARPN-IDSEYKEANSEIEKKIAEIWKSILKCDQIGINDSFFQLGGNSILLVRMHEELEKH 3967 Query: 2749 LKLTVEMGDLFKYPTISSLATFL 2771 + + LF + TI+ L+ F+ Sbjct: 3968 YPGKINVSKLFIHNTIAKLSEFI 3990 Score = 306 bits (783), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 223/897 (24%), Positives = 430/897 (47%), Gaps = 66/897 (7%) Query: 1889 WQQGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERI 1948 + ++S+ YR + +W ++L+ + D+ ++ + ++RI Sbjct: 4 YDNILLSSKKYREQRDFWCKQLSDIELTRMIELDFNASTEREL-NKKLYFTVQSDITDRI 62 Query: 1949 KKFSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLR 2008 K + +++ F+ + SG++ + + P + +D+ + +++LV R Sbjct: 63 IKIGKGSEMSIFIILLTAFEVFLYKYSGKNSLHVLSPVYKGSSKDLFFNDEIIIHNLVNR 122 Query: 2009 NQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNY 2068 NQ + L++ + ++ A ENQ++ +E I+ +L +++ +YD +F Sbjct: 123 NQS---------YKELLKKTKEDVVAAYENQEYPLEKILSELGIEKN-----VYDILFLS 168 Query: 2069 QSMKNQTETEASYLHDMKLSPYPMTSKTTKADLNIHLYEVPSGIYVECFYRTDLFKRETV 2128 Q++ N+T + H++ +S + ++ ++ L E IY EC TV Sbjct: 169 QNLHNKTVRDKK--HNLIIS-----YRHSEIGIDFTL-EYSDTIYNEC----------TV 210 Query: 2129 QYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDIPPAGGNVSPPVRFQAFHYND----PAE 2184 + I+ + +E + + IG + + + AF+ D + Sbjct: 211 KRIYNYFMTTLEECLKNPDQRIGLFSILNKEE---------KDTLLNAFNNTDYKFENKK 261 Query: 2185 NLVQRFEKQVAAYPAHTAVKYREESLNYRQLNEQANRIARRIWE--LKEQESVERPVALL 2242 ++ FE+Q A P TAV E+SL Y+QLN QAN+ A+ + E LK+ + V L+ Sbjct: 262 TIIDMFEEQAAIRPEDTAVVCSEKSLTYKQLNVQANKAAQMLIEKGLKKGDIV----GLI 317 Query: 2243 FGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAE 2302 G + + + + G +KAG ++P+D S P++R+ +M+ D+ A +L + + + EL Sbjct: 318 SGRSADTIIGIMGILKAGCAYLPIDPSYPVKRIEYMLTDSDAKAVLVQNTH---SHELE- 373 Query: 2303 RVHAKVTIVNTAEGLSGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIA 2362 + + I ++ + S +NP + D A+++YTSGS+G PKGV+ + N+ + Sbjct: 374 --YNGIIIDLNSKAFNNSSCDNPLISRGADDLAYVIYTSGSTGEPKGVMITLENVVNLVN 431 Query: 2363 QFTHSLAVNHQDRM--ALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLN 2420 ++ + R+ A++ + + I SLL G +L++ + + ++L + Sbjct: 432 GLELNIYRKYIGRLKVAIVAPFVFDASVQQIFTSLLFGHSLYIVPDDVRSDGKKLEGFYI 491 Query: 2421 SEGITLYHSVPSVFRFLMKNLPGDVKLPSLRMVLLGGEVVTRADFE-LYKKNCAEHCLFV 2479 I + P+ L N D+K ++ ++GGE + E Y + Sbjct: 492 ENKIDISDGTPNHLAGLALNASSDIKNMKVKHFIIGGEALHYTTVEKFYSRFEGNTPEIT 551 Query: 2480 NFLGCSELMVIS-FYTLDKGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQ 2538 N G +E V S FYTL+ +P G + + V I+GE+ +G++ Sbjct: 552 NVYGPTECCVDSTFYTLNPSDLAGSKIIPIGKPMPNVQVYILGENQELIPRGCIGEVYIS 611 Query: 2539 SEYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGY 2598 + GY ++ +T F P + K++Y++GD GR LP+G +E+ GR D Q+KIRGY Sbjct: 612 GTGVGVGYLSREQMTSERFIPNPFNVDKKMYKTGDLGRWLPDGNIEFIGRKDGQVKIRGY 671 Query: 2599 RVDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAY 2658 R++L EIE+ L I++++VT + + + AY+ E + L +++P Y Sbjct: 672 RIELGEIEAQLQKHENIREAVVTDRKEDSENKVLCAYFTANEKLGVTQLREHLSDKIPEY 731 Query: 2659 LIPRYWIELKFFPMTGPNKVDRNALPAP-DAIPSNDLRHEYVPPRNEMENMLARLWGEVL 2717 +IP Y+++++ P+T K+D+NALP P D + R EY+ PRN E L +W +V Sbjct: 732 MIPTYFVQIEKMPLTINGKLDKNALPNPKDTLKK---RTEYIEPRNNTEQSLVPIWQDVF 788 Query: 2718 GIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFLKDK 2774 I+ +G+ D F+E+GGHSL + + + + K+L + V + L P I +A ++ K Sbjct: 789 QIEKLGIKDDFYELGGHSLKAITLSSRIFKDLNVEVPISILLSTPNIEGIAKYIDSK 845 >O30409.1 TYCC_BREPA Tyrocidine synthetase 3 ATP-dependent asparagine adenylase ATP-dependent glutamine adenylase ATP-dependent tyrosine adenylase ATP-dependent valine adenylase ATP-dependent ornithine adenylase ATP-dependent leucine adenylase Length = 6486 Score = 679 bits (1751), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/1135 (34%), Positives = 625/1135 (55%), Gaps = 36/1135 (3%) Query: 1642 EKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIK 1701 E KL AI+E+ LG +PIG+ D FFEL G SLKA+HVIS +++ F ++ L F++ TI Sbjct: 2008 EAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAMHVISLLQRSFQVDVPLKVLFESPTIA 2067 Query: 1702 SVARFIRNASRANERQIAPVNPKSHYPTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNI 1761 +A + A + I PV + +YP S AQKR+F LQ + + YN + L+G + Sbjct: 2068 GLAPLVAAARKGTYTAIPPVEKQEYYPVSAAQKRMFILQQMEGAGISYNMPGFMYLDGKL 2127 Query: 1762 NAGRIEEVFAQIINRHESLRTSFRAENGEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFI 1821 + R+++ ++ RHESLRTSF + GE VQ +H VD + E + E+FI Sbjct: 2128 DTERLQQALKSLVQRHESLRTSFHSVQGETVQRVHDDVDLAISFGEATEAETRQIAEQFI 2187 Query: 1822 QPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIADGTSVNLLVNDFADLYMGKILPPLAI 1881 QPFDL APL+R GL++ ++ + ++D+HHI+ DG S+ LL+ +FA LY G+ LP L I Sbjct: 2188 QPFDLGTAPLLRAGLIKLAPERHLFMLDLHHIVVDGVSIGLLIEEFAQLYHGEELPALRI 2247 Query: 1882 QYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYPRPAALSFQGGRITLELD 1941 QYKD+A+WQQ + +E + +E YWL G +PVL LPTDYPRP+ SF G R Sbjct: 2248 QYKDFAKWQQDWFQTEEFAEQEAYWLNTFTGEIPVLNLPTDYPRPSVKSFAGDRFVFGSG 2307 Query: 1942 RPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGIPQAGRNHEDVQEMVGMF 2001 +++ + +QE T +M + S + DI++G P AGR+H + + +VGMF Sbjct: 2308 TALPKQLHQLAQETGTTLYMVLLAAYNVLLSKYSRQEDIIVGAPTAGRSHAETESIVGMF 2367 Query: 2002 VNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFL 2061 VN+L LRN+P K F FL EV+ + L A E+QD+ ++ +VD+LD +RD R L Sbjct: 2368 VNTLALRNEPAG----GKTFRDFLAEVKINTLGAFEHQDYPLDELVDKLDMQRDLSRNPL 2423 Query: 2062 YDTIFNYQSMKNQTETEASYLHDMKLSPYPMTSKTTKADLNIHLYEVPSGIYVECFYRTD 2121 +DT+F Q+M E + + + ++PY K K DL++ YE + I Y T Sbjct: 2424 FDTVFILQNM----EQKPFEMEQLTITPYSAEVKQAKFDLSLEAYEENAEIIFSLDYSTK 2479 Query: 2122 LFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDIPPAGGNVSPPVRFQAFHYND 2181 LF RET++ I + +++ A+ + + E+ + + + V F H + Sbjct: 2480 LFSRETIEKIATHFIQILRAVIAEPEMPLSEITMLTEAE------KQRLLVDFNGAHKDF 2533 Query: 2182 PAENLVQR-FEKQVAAYPAHTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERPVA 2240 P +Q FE+Q P TAV+ + L+Y++LNE+AN++A + E Q ++PV Sbjct: 2534 PQNKTLQALFEEQAEKSPQATAVEISGQPLSYQELNERANQLAATLRERGVQP--DQPVG 2591 Query: 2241 LLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIAREL 2300 ++ ++EMV + +KAG +VP+D P +R+ +M+ D QA L+LT + + +L Sbjct: 2592 IMANRSVEMVVGILAILKAGGAYVPIDPEYPEERVAYMLTDCQARLVLT---QKHLGAKL 2648 Query: 2301 AERVHAKVTIVNTAEGLSGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFY 2360 V A+ ++ E GV N A+I+YTSG++G PKGV+ +R I Sbjct: 2649 GSSVTAECLYLDD-ESNYGVHRSNLQPINTASDLAYIIYTSGTTGKPKGVMVEHRGIVNN 2707 Query: 2361 IAQFTHSLAVNHQDRMALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLN 2420 + + DR L +++ +L +L+GAT+ L + + L + Sbjct: 2708 VLWKKAEYQMKVGDRSLLSLSFAFDAFVLSFFTPVLSGATVVLAEDEEAKDPVSLKKLIA 2767 Query: 2421 SEGITLYHSVPSVFRFLMK-NLPGDVKLPSLRMVLLGGEVVTRADFELYKKNCAEHCLFV 2479 + TL VPS+F+ +++ + P D++ L+ V LGGE +T E K+ + V Sbjct: 2768 ASRCTLMTGVPSLFQAILECSTPADIR--PLQTVTLGGEKITAQLVEKCKQ-LNPDLVIV 2824 Query: 2480 NFLGCSELMVISFYTLDKGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQS 2539 N G +E V++ + G + A + G + + IV + + I VG++ Sbjct: 2825 NEYGPTESSVVATWQRLAGPD---AAITIGRPIANTSLYIVNQYHQLQPIGVVGEICIGG 2881 Query: 2540 EYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYR 2599 L+ GYWN+ +TE F S P + +R+Y++GD G+ LP+G +EY GR D Q+K+RGYR Sbjct: 2882 RGLARGYWNKPALTEEKFVSHPFAAGERMYKTGDLGKWLPDGTIEYIGRIDEQVKVRGYR 2941 Query: 2600 VDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAAYYVLKEPAAEKDIIRL---LREQLP 2656 +++ EIES L + ++V D G+ A+AAY+ E + D+ +L L ++LP Sbjct: 2942 IEIGEIESALLAAEKLTAAVVVVYEDQLGQSALAAYFTADE---QLDVTKLWSHLSKRLP 2998 Query: 2657 AYLIPRYWIELKFFPMTGPNKVDRNALPAPDAIPSNDLRHEYVPPRNEMENMLARLWGEV 2716 +Y+IP ++++L P+T KVD+ ALP P+ P + +YV P N +E+ LA +W V Sbjct: 2999 SYMIPAHFVQLDQLPLTPNGKVDKKALPKPEGKPVTE--AQYVAPTNAVESKLAEIWERV 3056 Query: 2717 LGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFL 2771 LG+ IG+ D FF+IGGHSL M V + +E ++ + + LF PTI +LA ++ Sbjct: 3057 LGVSGIGILDNFFQIGGHSLKAMAVAAQVHREYQVELPLKVLFAQPTIKALAQYV 3111 Score = 655 bits (1689), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/1165 (33%), Positives = 623/1165 (53%), Gaps = 40/1165 (3%) Query: 1618 PVTRKSQGKRPELP---------VAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELS 1668 P+T + +R +LP AY + E KL I++ LG +GI DDFF+L Sbjct: 938 PLTANGKVERKKLPKPAGAVVTGTAYAAPQNEIEAKLAEIWQQVLGISQVGIHDDFFDLG 997 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYP 1728 G SLKA+ V+ + K + L + F++ T+ +ARF+ + + I PV + YP Sbjct: 998 GHSLKAMTVVFQVSKALEVELPVKALFEHPTVAELARFLSRSEKTEYTAIQPVAAQEFYP 1057 Query: 1729 TSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN 1788 S AQKR++ LQ + + YN S ++LLEG ++ R Q+ RHE+LRTSF + Sbjct: 1058 VSSAQKRMYILQQFEGNGISYNISGAILLEGKLDYARFASAVQQLAERHEALRTSFHRID 1117 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE VQ +H V+ L E E+ + F++PFDL APL+R GLL+ G+ + + ++ Sbjct: 1118 GEPVQKVHEEVEVPLFMLEAPEDQAEKIMREFVRPFDLGVAPLMRTGLLKLGKDRHLFLL 1177 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 DMHHII+DG S +L+ +FA+LY G L PL++QYKD+A WQ +EAY+ +E +WL Sbjct: 1178 DMHHIISDGVSSQILLREFAELYQGADLQPLSLQYKDFAAWQNELFQTEAYKKQEQHWLN 1237 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 A +P+L LPTDYPRP+ SF G + + ER+++ + E T +M + Sbjct: 1238 TFADEIPLLNLPTDYPRPSVQSFAGDLVLFAAGKELLERLQQVASETGTTLYMILLAAYN 1297 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 +G+ DI++G P AGR+H DV+ ++G+FVN+L LRNQP K F FLQEV Sbjct: 1298 VLLSKYTGQEDIIVGTPVAGRSHADVENIMGIFVNTLALRNQPAS----SKTFAQFLQEV 1353 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 + + L A ++QD+ E +V++L +RD R L+DT+F+ ++ Q+ A ++ S Sbjct: 1354 KQNALAAYDHQDYPFEELVEKLAIQRDISRNPLFDTLFSLENANQQSLAIA----ELTAS 1409 Query: 2089 PYPMTSKTTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGR 2148 PY + +K +K DL ++ E P+ I + + T LFK+ETV+ + Y ++ I EQ Sbjct: 1410 PYELFNKISKFDLALNASESPADIQFQLTFATKLFKKETVERMARHYLEILRWISEQPTA 1469 Query: 2149 TIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQRFEKQVAAYPAHTAVKYREE 2208 ++ ++ + + + NV+ F A L Q E+Q A P AV Y E Sbjct: 1470 SLADIDMMTEAEKRTLLLNVN-----DTFVERTAATALHQLVEEQAARTPDEVAVVYEEY 1524 Query: 2209 SLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDR 2268 +L YR+LN +AN++AR + + + ++ + MV + +KAG + P+D Sbjct: 1525 ALTYRELNARANQLARLLR--SHGTGPDTLIGIMVDRSPGMVVGMLAVLKAGGAYTPIDP 1582 Query: 2269 SAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAE-NPSV 2327 S P +R+ +M++D+QA ++LT R L E + I++ E A+ N Sbjct: 1583 SYPPERIQYMLSDSQAPILLTQ-------RHLQELAAYQGEIIDVDEEAIYTGADTNLDN 1635 Query: 2328 CPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIG 2387 D A+++YTSGS+G PKGV+ S++ I ++ + + +D + T +S Sbjct: 1636 VAGKDDLAYVIYTSGSTGNPKGVMISHQAICNHMLWMRETFPLTTEDAVLQKTPFSFDAS 1695 Query: 2388 ILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKL 2447 + + L+ G L L I ++ + E IT VPS+ +M + PG Sbjct: 1696 VWEFYLPLITGGQLVLAKPDGHRDIAYMTRLIRDEKITTLQMVPSLLDLVMTD-PGWSAC 1754 Query: 2448 PSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMV-ISFYTLDKGSEVNHARL 2506 SL+ V GGE +T A + + + +N G +E + +++ + E ++ + Sbjct: 1755 TSLQRVFCGGEALTPALVSRFYET--QQAQLINLYGPTETTIDATYWPCPRQQE--YSAI 1810 Query: 2507 PAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAK 2566 P G +D + + +V S + + G+L + L+ GYW + +T+ F P Sbjct: 1811 PIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWQREELTKASFVDNPFEPGG 1870 Query: 2567 RLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDH 2626 +YR+GD R LP+G +EY GR D Q+KIRG+R++L EIE+TL ++ +V A D Sbjct: 1871 TMYRTGDMVRYLPDGHIEYLGRIDHQVKIRGHRIELGEIEATLLQHEAVKAVVVMARQDG 1930 Query: 2627 EGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAP 2686 +G+ ++ AY V ++ ++ L LPAY++P ++ L+ P++ KVDR ALP P Sbjct: 1931 KGQNSLYAYVVAEQDIQTAELRTYLSATLPAYMVPSAFVFLEQLPLSANGKVDRKALPQP 1990 Query: 2687 DAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLE 2746 + + YV PRNE E LA +W VLG++ IGV D FFE+GGHSL M V + L+ Sbjct: 1991 E--DAAASAAVYVAPRNEWEAKLAAIWESVLGVEPIGVHDHFFELGGHSLKAMHVISLLQ 2048 Query: 2747 KELKLTVEMGDLFKYPTISSLATFL 2771 + ++ V + LF+ PTI+ LA + Sbjct: 2049 RSFQVDVPLKVLFESPTIAGLAPLV 2073 Score = 645 bits (1665), Expect = 0.0, Method: Compositional matrix adjust. Identities = 378/1162 (32%), Positives = 613/1162 (52%), Gaps = 50/1162 (4%) Query: 1622 KSQGKRPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAIHVISSI 1681 K +GK P YV E KL I+E LG IGI D+FF++ G SLKA+ V + + Sbjct: 3027 KPEGK-PVTEAQYVAPTNAVESKLAEIWERVLGVSGIGILDNFFQIGGHSLKAMAVAAQV 3085 Query: 1682 RKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLAQKRIFFLQG 1741 +++ L L F TIK++A+++ + + I P + +YP S AQKR++ L+ Sbjct: 3086 HREYQVELPLKVLFAQPTIKALAQYVATSGKETYVPIEPAPLQEYYPVSSAQKRMYVLRQ 3145 Query: 1742 LMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIVQIIHPHVDF 1801 YN +++ +EG+++ R E ++ RHESLRTSF NGE VQ +H HV+ Sbjct: 3146 FADTGTVYNMPSALYIEGDLDRKRFEAAIHGLVERHESLRTSFHTVNGEPVQRVHEHVEL 3205 Query: 1802 KLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIADGTSVN 1861 + V E +E VE F+Q FDL +APL+RVGL + ++ + ++DMHHII+DG S Sbjct: 3206 NVQYAEVTEAQVEPTVESFVQAFDLTKAPLLRVGLFKLAAKRHLFLLDMHHIISDGVSAG 3265 Query: 1862 LLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLPVLTLPT 1921 +++ +F+ LY G+ LP L++ YKD+A WQ S+ Y E YWL +G +PVL LP Sbjct: 3266 IIMEEFSKLYRGEELPALSVHYKDFAVWQSELFQSDVYTEHENYWLNAFSGDIPVLNLPA 3325 Query: 1922 DYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESDIL 1981 D+ RP SF+G ++ + D+ + + K +QE Q T FM + SG+ DI+ Sbjct: 3326 DFSRPLTQSFEGDCVSFQADKALLDDLHKLAQESQSTLFMVLLAAYNVLLAKYSGQEDIV 3385 Query: 1982 IGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEALENQDF 2041 +G P AGR+H D++ ++GMFVN+L LRN P K F AFL+EV+ + L+A +QD+ Sbjct: 3386 VGTPIAGRSHADIENVLGMFVNTLALRNYPV----ETKHFQAFLEEVKQNTLQAYAHQDY 3441 Query: 2042 QIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLSPYPMTSKTTKADL 2101 E +V++LD +RD R L+DT+F Q++ + +A L +KL YP + K DL Sbjct: 3442 PFEALVEKLDIQRDLSRNPLFDTMFILQNL----DQKAYELDGLKLEAYPAQAGNAKFDL 3497 Query: 2102 NIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDI 2161 + +E +GI+ Y T LF+RE+++ + + +++ + + E+ + + + Sbjct: 3498 TLEAHEDETGIHFALVYSTKLFQRESIERMAGHFLQVLRQVVADQATALREISLLSEEE- 3556 Query: 2162 PPAGGNVSPPVRFQAFHYND-----PAENLVQR-FEKQVAAYPAHTAVKYREESLNYRQL 2215 R +N+ P + +Q FE+Q A P H AV + L YR+L Sbjct: 3557 ----------RRIVTVDFNNTFAAYPRDLTIQELFEQQAAKTPEHAAVVMDGQMLTYREL 3606 Query: 2216 NEQANRIARRIWELKEQESV--ERPVALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQ 2273 NE+AN++A + Q V E V LL ++EM+ + G +KAG ++ LD P + Sbjct: 3607 NEKANQLAHVL----RQNGVGKESIVGLLADRSLEMITGIMGILKAGGAYLGLDPEHPSE 3662 Query: 2274 RLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAENPSVCPDGDQ 2333 RL +M+ D ++L + E + IV E L NP++ Sbjct: 3663 RLAYMLEDGGVKVVLVQKHLLPLVGE------GLMPIVLEEESLRPEDCGNPAIVNGASD 3716 Query: 2334 TAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIGILDILA 2393 A+++YTSGS+G PKGV+ +RN+ + T+ + V DRM +I Sbjct: 3717 LAYVMYTSGSTGKPKGVMVEHRNVTRLVMH-TNYVQVRESDRMIQTGAIGFDAMTFEIFG 3775 Query: 2394 SLLNGATLHLC--DLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKLPSLR 2451 +LL+GA+L+L D+ LDA ++L +L + IT +F L ++ P SLR Sbjct: 3776 ALLHGASLYLVSKDVLLDA--EKLGDFLRTNQITTMWLTSPLFNQLSQDNPA--MFDSLR 3831 Query: 2452 MVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMVISFYTLDKGSEVNHARLPAGYA 2511 +++GGE ++ K + ++ + + Y +++ E ++P G Sbjct: 3832 ALIVGGEALSPKHINRVKSALPDLEIWNGYGPTENTTFSTCYLIEQHFE---EQIPIGKP 3888 Query: 2512 VDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKRLYRS 2571 + IV + + I G+L + ++ GY N+ +T F P + + +YR+ Sbjct: 3889 IANSTAYIVDGNNQPQPIGVPGELCVGGDGVARGYVNKPELTAEKFVPNPFAPGETMYRT 3948 Query: 2572 GDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHEGEQA 2631 GD R LP+G +EY GR D Q+KIRGYR++L EIE+ L +++++V + G++A Sbjct: 3949 GDLARWLPDGTIEYLGRIDQQVKIRGYRIELGEIETVLSQQAQVKEAVVAVIEEANGQKA 4008 Query: 2632 IAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAPDAIPS 2691 + AY+V ++ ++ + +QLP Y++P Y+++++ P+T KVDR ALP P Sbjct: 4009 LCAYFVPEQAVDAAELREAMSKQLPGYMVPAYYVQMEKLPLTANGKVDRRALPQPSG--E 4066 Query: 2692 NDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKL 2751 +V +N+ E L ++W EVLGI IG+ D FFEIGGHSL M V + K ++ Sbjct: 4067 RTTGSAFVAAQNDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAMNVITQVHKTFQV 4126 Query: 2752 TVEMGDLFKYPTISSLATFLKD 2773 + + LF PTI LA + + Sbjct: 4127 ELPLKALFATPTIHELAAHIAE 4148 Score = 632 bits (1631), Expect = e-178, Method: Compositional matrix adjust. Identities = 411/1207 (34%), Positives = 636/1207 (52%), Gaps = 81/1207 (6%) Query: 1618 PVTRKSQGKRPELP---------VAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELS 1668 P+T + R LP YV + E +L ++E L +G DDFF L Sbjct: 5092 PLTANGKVDRRSLPAPDVTMLRTTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALG 5151 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYP 1728 G SL+A+ V+SS+ ++ ++ L F+ TI+ +A FI ++ N I PV +++YP Sbjct: 5152 GHSLRAMRVLSSMHNEYQVDIPLRILFEKPTIQELAAFIEETAKGNVFSIEPVQKQAYYP 5211 Query: 1729 TSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN 1788 S AQKR++ L + YN +++L+EG + R+E F ++I RHESLRTSF N Sbjct: 5212 VSSAQKRMYILDQFEGVGISYNMPSTMLIEGKLERTRVEAAFQRLIARHESLRTSFAVVN 5271 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE VQ IH V F L + V EQ E V +QPFDL APLIRV LL+ GE + +L Sbjct: 5272 GEPVQNIHEDVPFALAYSEVTEQEARELVSSLVQPFDLEVAPLIRVSLLKIGEDRYVLFT 5331 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 DMHH I+DG S +L+ ++ LY G +LP L IQYKD+A WQQ F S A+ +E YWL+ Sbjct: 5332 DMHHSISDGVSSGILLAEWVQLYQGDVLPELRIQYKDFAVWQQEFSQSAAFHKQEAYWLQ 5391 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 A +PVL LPTD+ RP+ SF G + T+ + +E + + +Q T +M + Sbjct: 5392 TFADDIPVLNLPTDFTRPSTQSFAGDQCTIGAGKALTEGLHQLAQATGTTLYMVLLAAYN 5451 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 +G+ DI++G P GR+H D++ +VGMFVN+L +RN+P +R+K F FLQEV Sbjct: 5452 VLLAKYAGQEDIIVGTPITGRSHADLEPIVGMFVNTLAMRNKP----QREKTFSEFLQEV 5507 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 + + L+A +QD+ E +V++L RD R L+DT+F +Q N TE E L + L+ Sbjct: 5508 KQNALDAYGHQDYPFEELVEKLAIARDLSRNPLFDTVFTFQ---NSTE-EVMTLPECTLA 5563 Query: 2089 PYPMTSKT---TKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQ 2145 P+ MT +T K DL E + + Y T LF RET++ + + +I + Sbjct: 5564 PF-MTDETGQHAKFDLTFSATEEREEMTIGVEYSTSLFTRETMERFSRHFLTIAASIVQN 5622 Query: 2146 AGRTIGE----LPVFRQNDIPPAGGNVSPPVRFQAFHYNDPA------ENLVQRFEKQVA 2195 +GE LP +Q + AG +ND A + L Q FE+QV Sbjct: 5623 PHIRLGEIDMLLPEEKQQIL--AG-------------FNDTAVSYALDKTLHQLFEEQVD 5667 Query: 2196 AYPAHTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAG 2255 P A+ + E+SL Y +LNE+ANR+AR + + +R VA++ + EMV + G Sbjct: 5668 KTPDQAALLFSEQSLTYSELNERANRLARVLR--AKGVGPDRLVAIMAERSPEMVIGILG 5725 Query: 2256 AIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAE 2315 +KAG +VP+D P +R+ +++ D+ A L+L+ + + +++ + + + AE Sbjct: 5726 ILKAGGAYVPVDPGYPQERIQYLLEDSNAALLLSQAHLLPLLAQVSSELPECLDL--NAE 5783 Query: 2316 GLSGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDR 2375 +G+S N A+++YTSG++G PKGV+ ++ I + D+ Sbjct: 5784 LDAGLSGSNLPAVNQPTDLAYVIYTSGTTGKPKGVMIPHQGIVNCLQWRRDEYGFGPSDK 5843 Query: 2376 MALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQ---RLSSWLNSEGITLYHSVPS 2432 + +++ + + A LL GAT C L +A+ + L + + +T Y+ VPS Sbjct: 5844 ALQVFSFAFDGFVASLFAPLLGGAT---CVLPQEAAAKDPVALKKLMAATEVTHYYGVPS 5900 Query: 2433 VFRFLMKNLPGDVKLPSLRMVLLGGEVVTRADFELYKKNCAEH--CLFVNFLGCSELMVI 2490 +F+ ++ + LR V LGGE + +L +K +H N G +E V+ Sbjct: 5901 LFQAIL-DCSTTTDFNQLRCVTLGGE---KLPVQLVQKTKEKHPAIEINNEYGPTENSVV 5956 Query: 2491 SFYTLDKGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQA 2550 + T+ + E A + G + + V IV E I VG+L L+ GY N+ Sbjct: 5957 T--TISRSIEAGQA-ITIGRPLANVQVYIVDEQHHLQPIGVVGELCIGGAGLARGYLNKP 6013 Query: 2551 GVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLD 2610 +T F + P +R+Y++GD + +G +EY GR D Q+K+RGYR+++ EIES + Sbjct: 6014 ELTAEKFVANPFRPGERMYKTGDLVKWRTDGTIEYIGRADEQVKVRGYRIEIGEIESAVL 6073 Query: 2611 HIPFIQQSIVTATLDHEGEQA-IAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKF 2669 I Q++V A D + + AY+V + + L ++LPAY+IP Y++EL Sbjct: 6074 AYQGIDQAVVVARDDDATAGSYLCAYFVAATAVSVSGLRSHLAKELPAYMIPSYFVELDQ 6133 Query: 2670 FPMTGPNKVDRNALPAPDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFF 2729 P++ KVDR ALP P S+ EYV PRN E LA +W EVLG++ IG+ D FF Sbjct: 6134 LPLSANGKVDRKALPKPQQ--SDATTREYVAPRNATEQQLAAIWQEVLGVEPIGITDQFF 6191 Query: 2730 EIGGHS----LLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFLKDKHNHNDY----- 2780 E+GGHS LL+ +V ++ EL L + +F+YPTI +A F+ K + Y Sbjct: 6192 ELGGHSLKATLLIAKVYEYMQIELPLNL----IFQYPTIEKVADFITHKRFESRYGTAIL 6247 Query: 2781 LNQSKQR 2787 LNQ R Sbjct: 6248 LNQETAR 6254 Score = 629 bits (1622), Expect = e-177, Method: Compositional matrix adjust. Identities = 384/1181 (32%), Positives = 611/1181 (51%), Gaps = 44/1181 (3%) Query: 1616 PEPVTRKSQGKRPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAI 1675 P+P ++ G A+V A DTE KL I++ LG IGI D+FFE+ G SLKA+ Sbjct: 4061 PQPSGERTTGS------AFVAAQNDTEAKLQQIWQEVLGIPAIGIHDNFFEIGGHSLKAM 4114 Query: 1676 HVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLAQKR 1735 +VI+ + K F L L F TI +A I ++ I PV P + YP S AQKR Sbjct: 4115 NVITQVHKTFQVELPLKALFATPTIHELAAHIAESAFEQFETIQPVEPAAFYPVSFAQKR 4174 Query: 1736 IFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIVQII 1795 ++ L + YN + ++LEG ++ R ++ RHESLRTSF + NGE +Q + Sbjct: 4175 MYILHQFEGSGISYNVPSVLVLEGKLDYDRFAAAIQSLVKRHESLRTSFHSVNGEPLQRV 4234 Query: 1796 HPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIA 1855 HP V+ + E E ++ IQPFDL APL RV L++ G ++ + +DMHHII+ Sbjct: 4235 HPDVELPVRLLEATEDQSESLIQELIQPFDLEIAPLFRVNLIKLGAERHLFFMDMHHIIS 4294 Query: 1856 DGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLP 1915 DG S+ ++V + A LY GK L L IQYKD+A WQ S+ ++ +E +W AG +P Sbjct: 4295 DGVSLAVIVEEIASLYAGKQLSDLRIQYKDFAVWQTKLAQSDRFQKQEDFWTRTFAGEIP 4354 Query: 1916 VLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXS 1975 +L LP DYPRP+ SF G + L E+++K + E T FM + + Sbjct: 4355 LLNLPHDYPRPSVQSFDGDTVALGTGHHLLEQLRKLAAETGTTLFMVLLAAYHVLLSKYA 4414 Query: 1976 GESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEA 2035 G+ +I++G P AGR+H DV+ +VGMFVN+L L+N F AFL++V+ + L A Sbjct: 4415 GQEEIVVGTPIAGRSHADVERIVGMFVNTLALKNTAAGSLS----FRAFLEDVKQNALHA 4470 Query: 2036 LENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLSPYPMTSK 2095 E+QD+ E +V++L +RD R L+DT+F+ + E E + D+K+SPYP+ Sbjct: 4471 FEHQDYPFEHLVEKLQVRRDLSRNPLFDTMFSL-GLAESAEGEVA---DLKVSPYPVNGH 4526 Query: 2096 TTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPV 2155 K DL++ E G+ V+ Y T LF +ETV + Y +L++ I + + V Sbjct: 4527 IAKFDLSLDAMEKQDGLLVQFSYCTKLFAKETVDRLAAHYVQLLQTITADPDIELARISV 4586 Query: 2156 FRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQR-FEKQVAAYPAHTAVKYREESLNYRQ 2214 + + + F A P + Q+ FE+QV P AV + E L Y++ Sbjct: 4587 LSKAETEHMLHS------FLATKTAYPTDKTFQKLFEEQVEKTPNEIAVLFGNEQLTYQE 4640 Query: 2215 LNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQR 2274 LN +AN++AR + ++ E V +L ++ MV + +KAG FVP+D PL+R Sbjct: 4641 LNAKANQLARVLR--RKGVKPESTVGILVDRSLYMVIGMLAVLKAGGTFVPIDPDYPLER 4698 Query: 2275 LIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAENPSVCPDGDQT 2334 M+ D++A L+LT + S E + V+ E + P + Sbjct: 4699 QAFMLEDSEAKLLLTLQKMNSQVAFPYETFYLDTETVDQEETGNLEHVAQP------ENV 4752 Query: 2335 AFILYTSGSSGIPKGVV---QSYRNIAFYIAQFTH--SLAVNHQDRMALLTTYSHAIGIL 2389 A+I+YTSG++G PKGVV +SY N+AF H S V R+ + +++ + Sbjct: 4753 AYIIYTSGTTGKPKGVVIEHRSYANVAFAWKDEYHLDSFPV----RLLQMASFAFDVSTG 4808 Query: 2390 DILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNL-PGDVKLP 2448 D +LL G L +C + L + IT++ + P++ LM + ++ + Sbjct: 4809 DFARALLTGGQLVICPNGVKMDPASLYETIRRHEITIFEATPALIMPLMHYVYENELDMS 4868 Query: 2449 SLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMV-ISFYTLDKGSEVNHARLP 2507 +++++LG + DF+ + +N G +E + S+Y + + +P Sbjct: 4869 QMKLLILGADSCPAEDFKTLLARFGQKMRIINSYGVTEACIDTSYYEETDVTAIRSGTVP 4928 Query: 2508 AGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKR 2567 G + + + +V + VG+L ++ GY N+ +TE F P + +R Sbjct: 4929 IGKPLPNMTMYVVDAHLNLQPVGVVGELCIGGAGVARGYLNRPELTEEKFVPNPFAPGER 4988 Query: 2568 LYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHE 2627 LYR+GD + +G +E+ GRND Q+KIRG R++L EIE+ L + I +++V A D Sbjct: 4989 LYRTGDLAKWRADGNVEFLGRNDHQVKIRGVRIELGEIETQLRKLDGITEAVVVAREDRG 5048 Query: 2628 GEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAPD 2687 E+ + AY V ++ L ++LP +IP Y++ L P+T KVDR +LPAPD Sbjct: 5049 QEKELCAYVVADHKLDTAELRANLLKELPQAMIPAYFVTLDALPLTANGKVDRRSLPAPD 5108 Query: 2688 AIPSNDLR-HEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLE 2746 LR EYV PR+ E LA++W +VL + +G D FF +GGHSL M+V +++ Sbjct: 5109 V---TMLRTTEYVAPRSVWEARLAQVWEQVLNVPQVGALDDFFALGGHSLRAMRVLSSMH 5165 Query: 2747 KELKLTVEMGDLFKYPTISSLATFLKDKHNHNDYLNQSKQR 2787 E ++ + + LF+ PTI LA F+++ N + + Q+ Sbjct: 5166 NEYQVDIPLRILFEKPTIQELAAFIEETAKGNVFSIEPVQK 5206 Score = 299 bits (766), Expect = 3e-78, Method: Compositional matrix adjust. Identities = 261/1075 (24%), Positives = 499/1075 (46%), Gaps = 79/1075 (7%) Query: 1727 YPTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRA 1786 YP + Q+ + F + Y S +EG+ + E+ +++ +E LRT+F Sbjct: 11 YPLTPLQEGMLFHAVTDTGSSAYCLQMSATIEGDFHLPLFEKSLNKLVENYEVLRTAFVY 70 Query: 1787 ENGEIVQIIHPHVDFKLIRTAVKEQGIE-----------EAVERFIQPFDLARAPLIRVG 1835 +N + + V FK + V + I +A + FDL + L++ Sbjct: 71 QNMQRPR----QVVFKERKVTVPCENIAHLPSAEQDAYIQAYTKQHHAFDLTKDNLMKAA 126 Query: 1836 LLQAGEQQSILVVDMHHIIADGTSVNLLVND----FADLYMGKILPPLAIQ-YKDYAEWQ 1890 + Q E + LV HHII DG ++ +L++ +A L G+ +P A + Y +Y +W Sbjct: 127 IFQTAENKYRLVWAFHHIIVDGWTLGVLLHKLLTYYAALRKGEPIPREATKPYSEYIKWL 186 Query: 1891 QGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKK 1950 EA YW LAG P A ++ + ++++ + Sbjct: 187 DKQNKDEAL----AYWQNYLAGYDHQAAFPKKKLGTEASRYEHVEAMFTIAPEKTQQLIQ 242 Query: 1951 FSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGIPQAGR--NHEDVQEMVGMFVNSLVLR 2008 + + Q T D++ G +GR + ++ MVG+F+N++ R Sbjct: 243 IANQNQATMSSVFQALWGILASTYKNADDVVFGSVVSGRPPQIQGIESMVGLFINTIPTR 302 Query: 2009 NQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNY 2068 Q +++ F LQ V+ +AL + + + Y+ + I + Sbjct: 303 VQ----TNKQQTFSELLQTVQK---QALASATYDFAPL-----YEIQSTTVLKQELIDHL 350 Query: 2069 QSMKNQTETEASYLHDMKLSPYPMTS--KTTKADLNIHLYEVPSG-IYVECFYRTDLFKR 2125 + +N + +L + + + S + T DLN+ + PS +YV+ Y +++ Sbjct: 351 VTFENYPDHSMKHLEESLGFQFTVESGDEQTSYDLNVVVALAPSNELYVKLSYNAAVYES 410 Query: 2126 ETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDIPPAGGNVSPPVRFQAF-HYNDPA- 2183 V I R +I+ + IG P ++I G ++ + Q YND A Sbjct: 411 SFVNRIEGHLRTVIDQV-------IGN-PHVHLHEI----GIITEEEKQQLLVAYNDTAA 458 Query: 2184 -----ENLVQRFEKQVAAYPAHTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERP 2238 + + + +Q + PA AV E++L Y++L E++ ++A + E + + Sbjct: 459 EYPRDKTIFELIAEQASRTPAKAAVVCGEDTLTYQELMERSAQLANALRE--KGIASGSI 516 Query: 2239 VALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIAR 2298 V+++ +++E++ A+ +++G ++P+D P R+ ++++D+Q TL+LT S + R Sbjct: 517 VSIMAEHSLELIVAIMAVLRSGAAYLPIDPEYPQDRIQYLLDDSQTTLLLTQSHLQPNIR 576 Query: 2299 ELAERVHAKVTIVNTAEGLSGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIA 2358 ++ + + EG G ++ P PD A+++YTSGS+G PKG + +++ + Sbjct: 577 FAGSVLY--LDDRSLYEG--GSTSFAPESKPD--DLAYMIYTSGSTGNPKGAMITHQGLV 630 Query: 2359 FYIAQFTHSLAVNHQDRMALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSW 2418 YI L ++ S + + I LL+G T+H+ + +Q + Sbjct: 631 NYIWWANKVYVQGEAVDFPLYSSISFDLTVTSIFTPLLSGNTIHVY--RGADKVQVILDI 688 Query: 2419 LNSEGITLYHSVPSVFRFLMKNLPGDVKLPSLRMVLLGGE-VVTRADFELYKKNCAEHCL 2477 + + + P+ + L++++ G K S+R ++GGE + T+ ++Y + E+ Sbjct: 689 IKDNKVGIIKLTPTHLK-LIEHIDG--KASSIRRFIVGGENLPTKLAKQIYD-HFGENVQ 744 Query: 2478 FVNFLGCSELMVISFYTLDKGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVY 2537 N G +E +V L +P G D + + ++ S + + +G++ Sbjct: 745 IFNEYGPTETVVGCMIYLYDPQTTTQESVPIGVPADNVQLYLLDASMQPVPVGSLGEMYI 804 Query: 2538 QSEYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRG 2597 + ++ GY+N+ +T+ F P ++YR+GD + LP+G +EY GR D Q+KIRG Sbjct: 805 AGDGVAKGYFNRPELTKEKFIDNPFRPGTKMYRTGDLAKWLPDGNMEYAGRMDYQVKIRG 864 Query: 2598 YRVDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAAYYVLKEPAAEKDIIRLLREQLPA 2657 +R+++ EIE+ L +++++V D G+ + AY V + ++ L LP+ Sbjct: 865 HRIEMGEIETRLTQHEAVKEAVVIVEKDESGQNVLYAYLVSERELTVAELREFLGRTLPS 924 Query: 2658 YLIPRYWIELKFFPMTGPNKVDRNALPAP-DAIPSNDLRHEYVPPRNEMENMLARLWGEV 2716 Y+IP ++I L P+T KV+R LP P A+ + Y P+NE+E LA +W +V Sbjct: 925 YMIPSFFIRLAEIPLTANGKVERKKLPKPAGAVVTGT---AYAAPQNEIEAKLAEIWQQV 981 Query: 2717 LGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFL 2771 LGI +G+ D FF++GGHSL M V + K L++ + + LF++PT++ LA FL Sbjct: 982 LGISQVGIHDDFFDLGGHSLKAMTVVFQVSKALEVELPVKALFEHPTVAELARFL 1036 >C0ZDA6.1 C0ZDA6_BREBN Tyrocidine synthetase II EC=5.1.1.11 Length = 3589 Score = 676 bits (1744), Expect = 0.0, Method: Compositional matrix adjust. Identities = 397/1187 (33%), Positives = 650/1187 (54%), Gaps = 49/1187 (4%) Query: 1618 PVTRKSQGKRPELPVA---------YVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELS 1668 PVT + R LP+ Y+ T+ E+K+ AI+E+ LG PIGI+D+FF L Sbjct: 945 PVTPNGKTDRRALPIPEGNAFTGADYLAPTTELEQKMAAIWESVLGVSPIGIQDNFFTLG 1004 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYP 1728 G SLKAIH+IS ++K ++ L F TI+ +A+++ I V + HYP Sbjct: 1005 GHSLKAIHLISRMQKDCQTDVPLRVLFDRPTIQEIAKYVEGEEAGTYLAIPQVTMQEHYP 1064 Query: 1729 TSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN 1788 S AQKR+ L L P + YN +L+G +N ++E + +++RHESLRTSF N Sbjct: 1065 VSSAQKRMLILNQLDPASTVYNLPVVTVLDGELNVPQMENAISGLVSRHESLRTSFHTIN 1124 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE+VQ IHP + E + + + F++PFDL +APL RVGL++ GE++ ++++ Sbjct: 1125 GELVQRIHPECKLPIAYMEATENRLNQVITDFMRPFDLEKAPLSRVGLVKLGERRHVMII 1184 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 DMHHII+DG S +++ND A LY K LP IQYKD+A W++G ++ YR +E YW + Sbjct: 1185 DMHHIISDGVSSQIILNDLAQLYQDKSLPEQRIQYKDFAVWEKGLAQTDEYRKQEAYWTQ 1244 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 + A +PVL LP DY RP+ S +G R ++ S+ +++ + E T +M + Sbjct: 1245 RFADEIPVLNLPLDYSRPSVQSSEGERYLFRSEKQLSDGLQRVAAETGTTLYMVLMAAYH 1304 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 SG+ D+++G AGR H D + + GMFVN+L +RNQP K F FLQEV Sbjct: 1305 VLLAKYSGQEDMVVGTVTAGRTHPDTESITGMFVNTLAMRNQPVAT----KSFKQFLQEV 1360 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 + + L A E+ ++ E +V++L R+ R L+DT+F Q+M + + + M ++ Sbjct: 1361 KDNTLAAFEHGEYPFEELVEKLAVNRNRSRNPLFDTLFILQNM----DADPINIEGMTVT 1416 Query: 2089 PYPMTSKTTKADLNIHLYEVPSGIYVECF-YRTDLFKRETVQYIFEEYRRLIEAIPEQAG 2147 PY K K DL++ + +G+ CF + T LFK+ET++ + Y ++++ I + Sbjct: 1417 PYVPEGKMAKFDLSLEATQNHAGLLF-CFEFCTKLFKQETIERMSRHYIQILQEITQNTN 1475 Query: 2148 RTIGELPVF---RQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQRFEKQVAAYPAHTAVK 2204 + E+ + + ++ + S PV+ ++ L Q FE+QV P A+ Sbjct: 1476 LALYEIEMLTEQEKQELLVHFNDTSKPVQLES--------TLTQLFEEQVGKTPDQIALV 1527 Query: 2205 YREESLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFV 2264 ++ L Y++LN++AN++AR + K+ ++ V ++ ++EMV + +K+G +V Sbjct: 1528 CGDKKLTYQELNKKANQLARTL--RKKGVKADQRVGIMANRSLEMVIGILAILKSGGAYV 1585 Query: 2265 PLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAEN 2324 P+D P R+ +M+ D +A L+LT L +V A V + E S S Sbjct: 1586 PIDPEYPNDRIAYMLEDCEARLVLTQ-------EHLGAKVAAGVECL-YLEDKSNYSRIT 1637 Query: 2325 PSVCPDGDQT--AFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTY 2382 ++ P T A+I+YTSG++G PKGV+ +R I + LA++ DR L ++ Sbjct: 1638 TNLDPIHTATHLAYIIYTSGTTGKPKGVMGEHRGIVNSVTWNKQELALSVHDRGLLPLSF 1697 Query: 2383 SHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLP 2442 + L A +++G+T+ L + L + ++S + VPS+F+ +++ Sbjct: 1698 AFDAFALTFFALIISGSTVVLTKDEEAKDPIALKNLISSWSCSYTVCVPSMFQAILECST 1757 Query: 2443 GDVKLPSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMVISFYTLDKGSEVN 2502 + ++ L+MV+LGGE ++ E+ K+ + + VN G +E VI+ Y D + Sbjct: 1758 TE-EISPLKMVMLGGEKLSPKLVEMCKEMNPQ-MITVNAYGPTESSVIATYLCDA---LP 1812 Query: 2503 HARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPD 2562 A + G + + IV S + I VG++ L+ GYWN+ +TE F S P Sbjct: 1813 DAPITIGRPIANTSIYIVDHSHQLLPIGVVGEICIGGLGLARGYWNKPELTEEKFVSNPF 1872 Query: 2563 SGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTA 2622 +R+Y++GD GR LP+G +E+ GR D Q+K+RGYR+++ EIES L ++IV A Sbjct: 1873 VPGERMYKTGDLGRWLPDGTIEFAGRLDEQVKVRGYRIEIGEIESVLFSYEMTNEAIVVA 1932 Query: 2623 TLDHEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNA 2682 D G+ +AAY+ KE +E + L ++LPAY++P Y ++L FP+T K+DR A Sbjct: 1933 YQDGSGDAYLAAYFTGKENISEVALRTHLSQELPAYMVPTYLVQLDTFPLTPNGKIDRKA 1992 Query: 2683 LPAPDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQ 2742 LP P+ P+ + EY P NE+E LA++W VLGI IGV D FFE+GGHSL M V Sbjct: 1993 LPKPEGKPTTGV--EYAAPANEVEATLAKIWENVLGISGIGVMDNFFELGGHSLKAMTVV 2050 Query: 2743 NNLEKELKLTVEMGDLFKYPTISSLATFLKDKHNHNDYLNQSKQRGE 2789 ++ +E ++ + + F+ PT+ +L+ + + N +D L Q +R E Sbjct: 2051 AHVHREFQIDLTLKHFFEQPTVRALSRLIANSENTSDALIQPAERQE 2097 Score = 650 bits (1676), Expect = 0.0, Method: Compositional matrix adjust. Identities = 373/1165 (32%), Positives = 628/1165 (53%), Gaps = 46/1165 (3%) Query: 1622 KSQGKRPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAIHVISSI 1681 K +GK P V Y + E L I+EN LG IG+ D+FFEL G SLKA+ V++ + Sbjct: 1995 KPEGK-PTTGVEYAAPANEVEATLAKIWENVLGISGIGVMDNFFELGGHSLKAMTVVAHV 2053 Query: 1682 RKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLAQKRIFFLQG 1741 ++F +LTL FF+ T+++++R I N+ ++ I P + +YP S AQ+R++ L Sbjct: 2054 HREFQIDLTLKHFFEQPTVRALSRLIANSENTSDALIQPAERQEYYPVSSAQQRMYVLHQ 2113 Query: 1742 LMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIVQIIHPHVDF 1801 L + YN ++LEG ++ ++ +++RHE RTSF ++VQ IH V+ Sbjct: 2114 LEGAGISYNTPGMIMLEGQLDRDQMVHALQALVDRHEIWRTSFEMLGDQLVQKIHDRVEV 2173 Query: 1802 KLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIADGTSVN 1861 ++ + +E I+E + F+ PFDLA PL+R+GL+Q +++ +L+ DMHHI +D +SV Sbjct: 2174 EMAYRSAEEHQIDEIFQAFVHPFDLAVPPLLRMGLVQISDERHVLLYDMHHIASDASSVP 2233 Query: 1862 LLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLPVLTLPT 1921 L+ N+ A+LY G+ LP L IQYKD++ WQ+ F S+ ++ +E YW G VL +PT Sbjct: 2234 LIFNELAELYQGRQLPELRIQYKDFSVWQKRFTESDDFKKQEEYWRHAFEGHNSVLEIPT 2293 Query: 1922 DYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESDIL 1981 D+PRP SF+G +I L DRP E + + E + T FM + +G+ DI+ Sbjct: 2294 DFPRPPVKSFEGDQIVLATDRPLLEALHALAAETKTTLFMVLLAAYNVLLSKYTGQDDIV 2353 Query: 1982 IGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEALENQDF 2041 +G P +G+ +++ +VGMFVN+L +RN+P +K F FL EV+ + L+A ++QD+ Sbjct: 2354 VGTPISGKTRAELEPIVGMFVNTLAIRNKPTA----EKTFKEFLMEVKQNALDAYDHQDY 2409 Query: 2042 QIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLSPYPMTS--KTTKA 2099 +E +V++L +RDPGR L+DT+F Q+ E L + PY TS +K Sbjct: 2410 PLESLVEKLGIQRDPGRNPLFDTMFILQT----DELYQKTLGQLTYHPYEPTSALAISKF 2465 Query: 2100 DLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQN 2159 DL+ HL E + + + Y T LF+R+TV + + +++ + + R + + + Sbjct: 2466 DLSFHLTERETDLLLRLEYSTKLFRRDTVDRMSRHFMQILRNVAAEPDRQLQAIEMLTAE 2525 Query: 2160 DIPPAGGNVSPPVRFQAFHYND----PAENLVQRFEKQVAAYPAHTAVKYREESLNYRQL 2215 + + F++ D + + Q FE+ VA P TA+ + E+ + Y +L Sbjct: 2526 E---------KQLLLVEFNHTDREYTEDQTIQQLFEELVANTPDQTAIVFEEKQMTYEEL 2576 Query: 2216 NEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRL 2275 NE+AN++A + E S + V ++ ++EMV A +KAG F+P+D P +R+ Sbjct: 2577 NERANQLATVLREKGLGPS--QIVVMMVERSLEMVIATLAILKAGGAFLPVDPDYPEERI 2634 Query: 2276 IHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAENPSVCPDG-DQT 2334 +M+ D+QA L+LT S L +V ++ I++ + S + + +C + Sbjct: 2635 RYMIEDSQAKLVLTHS-------HLIHKVSSQAEIIDLGDAESYSAQTDNLLCINKPSDL 2687 Query: 2335 AFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIGILDILAS 2394 A+I+YTSG++G PKGV+ ++ A A F + V QDR + S + D+ + Sbjct: 2688 AYIIYTSGTTGNPKGVMLEHKGAANLQAMFKNHFGVTPQDRPGHFASISFDASVWDMFMA 2747 Query: 2395 LLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKLPSLRMVL 2454 LL GATL++ ++ +++ GIT+ P+ +L + ++PSLR+++ Sbjct: 2748 LLTGATLYIISRDTINDFRKFEEYVHKNGITILTLPPTYAIYLEPD-----RMPSLRILI 2802 Query: 2455 LGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMVISFYTLDKGSEVNHARLPAGYAVDG 2514 G + A E +K E ++N G +E + + E + G + Sbjct: 2803 TAGSAASTALVEQWK----EKVTYINAYGPTESTICATTWKALPHEPVGQTITIGKPIQN 2858 Query: 2515 IDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDY 2574 + IV E + + ++G+L L+ GYWN+ +T F P +++YR+GD Sbjct: 2859 TKLFIVDEQMQLKTVGQIGELCISGVALARGYWNRPELTAEKFVDNPFVPGEKMYRTGDL 2918 Query: 2575 GRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAA 2634 + LP+G +EY GR D Q+K+RG+RV+L E+ES L I +++ LD G+ + A Sbjct: 2919 AKWLPDGNIEYLGRIDHQVKVRGHRVELGEVESVLLRYETIVEAVAITHLDDLGQPYLCA 2978 Query: 2635 YYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAPDAIPSNDL 2694 YYV A+ + + ++LP Y++P +++++ P+T +K+DR ALP P Sbjct: 2979 YYVADGAASPAQLREFMGKELPNYMVPSFFVQMDKMPLTPNDKIDRKALPKPSH--EEKP 3036 Query: 2695 RHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVE 2754 EY P+NE+E++LA W EVLGI +G+ D FFE+GG S+ +QV L T+ Sbjct: 3037 GREYEAPQNELEHLLATTWAEVLGIGQVGMKDNFFELGGDSIKAIQVSTRLHAA-GWTLA 3095 Query: 2755 MGDLFKYPTISSLATFLKDKHNHND 2779 M +LF+YPTI +A + + +D Sbjct: 3096 MKELFQYPTIEQVAAHVIPNNRESD 3120 Score = 304 bits (779), Expect = 8e-80, Method: Compositional matrix adjust. Identities = 269/1081 (24%), Positives = 497/1081 (45%), Gaps = 138/1081 (12%) Query: 1754 SVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN-GEIVQIIHPHVDFKLIRTAVKEQG 1812 SV +EGN++ G ++ R + RT F E + +Q++ ++ + Sbjct: 40 SVSIEGNLDVGLYTNSLHVLVERFDVFRTLFLYEKLKQPLQVVMKERPIPILFCDLTAYD 99 Query: 1813 IEEAVERFIQ--------PFDLARAPLIRVGLLQAGEQQSILVVDMHHIIADGTSVNLLV 1864 +E +R+ Q F LA+ L+RV + Q E + ++ HHI+ DG +++ Sbjct: 100 EQEKQQRYTQYKRNDQEKTFHLAKDSLMRVAIFQMTESKYEIIWSFHHILMDGWCFSIIF 159 Query: 1865 NDFADLYMG-KILPPLAIQ----YKDYAEWQQGFITSEAYRSKETYWLEKLAGPLPVLTL 1919 +D +Y+ K P+++ Y + W + + + YW + L +L Sbjct: 160 DDLLSVYLSLKNGAPISLDPVQPYSQFIRW----LGKQDKEAALAYWRDYLEQFEQQTSL 215 Query: 1920 PTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESD 1979 P + + ++ +F + LDR ++++ + + QVT + + +D Sbjct: 216 PR-FGKSSSNAFLPAQYRFVLDRMVTQQLSAIASQNQVTLPTVIQTLWGILLQSYNTTND 274 Query: 1980 ILIGIPQAGRNHE--DVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEALE 2037 +L G +GR E + +MVG+F+N++ R Q + + F+ +Q+V ++ Sbjct: 275 VLFGSVVSGRPTEIVGIDKMVGLFINTIPFRVQ----AKNDQTFVDLIQDVHQRTRQSQP 330 Query: 2038 NQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYL-HDMKLSPYPMTSK- 2095 Y+ P LYD ++N + + + H M + YP+ Sbjct: 331 --------------YEHVP----LYD-------IQNDSVLKQDLIDHLMVIENYPLVEAL 365 Query: 2096 TTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQ--AGRTIGEL 2153 KA+ + + + VE F T+ Y + +P++ A R Sbjct: 366 QKKAETRQVCFAI---VNVEMFEPTN-------------YDMTVMVMPKEEIAMRFDYNA 409 Query: 2154 PVFRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQ-----RFEKQ---------VAAYPA 2199 VF I G++ + A N+P NL Q EKQ AAYP Sbjct: 410 AVFDDAFIQKMAGHLKQIATWVA---NNPRVNLQQVTLLTETEKQQLMARNLDTSAAYPT 466 Query: 2200 ----------------HTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERPVALLF 2243 H AV + E+ L YR+L+E++N++AR + + + + V + Sbjct: 467 KTMHELFMEQVERTPDHVAVVFGEQHLTYRELDEKSNQLARFL--RGKGIAADSLVGTMM 524 Query: 2244 GNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAER 2303 +IEM+ + G +KAG FVP+D P +R+ +M+ + ++T + L E+ Sbjct: 525 DRSIEMIVGILGVLKAGGAFVPIDPELPEERIAYMLEHSGIQWVVTQ-------QHLLEK 577 Query: 2304 VHAKV-TIVNTAEGLSGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIA 2362 + A TI +A + S+ + + + +I+YTSG++G PKGV+ ++N+A + Sbjct: 578 LSASTETIDISAPAIWEESSASVEMINQPEDLFYIIYTSGTTGKPKGVMLEHQNMA-NLM 636 Query: 2363 QFTHSLA-VNHQDRMALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLNS 2421 FT + ++ +++ TT S + +I ++LL+G L+L ++ ++++L +++ Sbjct: 637 HFTFAKTNIDFHEKVLQYTTCSFDVCYQEIFSTLLSGGQLYLITNEMRRNVEKLFAFIQE 696 Query: 2422 EGITLYHSVPSVFRFLM------KNLPGDVKLPSLRMVLLGGEVVTRADFELYKKNCAEH 2475 I++ S +F+ ++ P VK ++ G ++V + + Y +N H Sbjct: 697 NQISILSLPVSFLKFIFNEKDYAQSFPRCVK----HIITAGEQLVVTHELQKYLRN--HH 750 Query: 2476 CLFVNFLGCSELMVISFYTLDKGSEVNHARLPAGYAVDGIDVRIVGES--GREAGIFEVG 2533 N G SE V++ YT+D ++ P G + + I+ E + GI VG Sbjct: 751 VFLHNHYGPSETHVVTTYTMDPSMDIPELP-PIGKPISNTGIYILDEKLQLKPEGI--VG 807 Query: 2534 QLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQL 2593 +L + GY + +T F P +R+YR+GD R +P+G +E+ GR D Q+ Sbjct: 808 ELYISGANVGRGYLHNPELTAEKFLENPYQSGERMYRTGDLARWMPDGNIEFLGRIDHQV 867 Query: 2594 KIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAAYYVLKEPAAEKDIIRLLRE 2653 KIRG+R++L EIES L + I++++V D G + + AY VL E + +++ L Sbjct: 868 KIRGHRIELGEIESHLLNHALIKEAVVIDRTDETGGKYLCAYVVLAEEVSNEELRAYLSR 927 Query: 2654 QLPAYLIPRYWIELKFFPMTGPNKVDRNALPAPD--AIPSNDLRHEYVPPRNEMENMLAR 2711 LP Y+IP ++++L+ P+T K DR ALP P+ A D Y+ P E+E +A Sbjct: 928 TLPEYMIPSFFMKLERIPVTPNGKTDRRALPIPEGNAFTGAD----YLAPTTELEQKMAA 983 Query: 2712 LWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFL 2771 +W VLG+ IG+ D FF +GGHSL + + + ++K+ + V + LF PTI +A ++ Sbjct: 984 IWESVLGVSPIGIQDNFFTLGGHSLKAIHLISRMQKDCQTDVPLRVLFDRPTIQEIAKYV 1043 Query: 2772 K 2772 + Sbjct: 1044 E 1044 Score = 101 bits (252), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 80/324 (24%), Positives = 139/324 (42%), Gaps = 28/324 (8%) Query: 1613 KNGPEPVTRKSQGKRPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSL 1672 K P+P + G+ E P + E L + LG +G++D+FFEL GDS+ Sbjct: 3025 KALPKPSHEEKPGREYEAP------QNELEHLLATTWAEVLGIGQVGMKDNFFELGGDSI 3078 Query: 1673 KAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLA 1732 KAI V + + L + + FQ TI+ VA + +R +++ + L Sbjct: 3079 KAIQVSTRLHAA-GWTLAMKELFQYPTIEQVAAHVIPNNRESDQGVVEGE------IDLT 3131 Query: 1733 QKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIV 1792 + +F + D +N++ + E + G +++ F +I+ H++LR ++ EN I Sbjct: 3132 PIQKWFFERNFTDRHHWNQAVMLFREDGFDPGLVQQAFYKIVEHHDALRMIYKQENETIT 3191 Query: 1793 QIIHPHVD--FKLIRTAVKEQG-----IEEAVERFIQPFDLARAPLIRVGLLQAGEQQSI 1845 QI F+ +K+ I E DL + PL+ + L E + Sbjct: 3192 QINRALTGERFRFHSYDLKDHANSAAHIWELSNHIQSSIDLEQGPLVHLALFSTTEGDHL 3251 Query: 1846 LVVDMHHIIADGTSVNLLVNDFADLYMGK------ILPPLAIQYKDYAEWQQGFITSEAY 1899 L+ +HH++ DG S +L DF+ Y +LP +KD++ Q + S+ Sbjct: 3252 LIA-IHHLVVDGVSWRILFEDFSSAYSQALHNQEIVLPKKTDSFKDWSAQLQNYAESDEL 3310 Query: 1900 RSKETYWLEKLAGPLPVLTLPTDY 1923 + YW L LPTD+ Sbjct: 3311 LREAAYW-HNLESTATAEKLPTDF 3333 >C0ZDA7.1 C0ZDA7_BREBN Tyrocidine synthetase III Length = 6487 Score = 673 bits (1737), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/1166 (33%), Positives = 628/1166 (53%), Gaps = 42/1166 (3%) Query: 1618 PVTRKSQGKRPELP---------VAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELS 1668 P+T + +R +LP AYV +TE KL I++ LG +G+ D FF+L Sbjct: 938 PLTANGKVERKKLPKPDGAVVTGTAYVAPQNETETKLAEIWQQVLGVSRVGVHDHFFDLG 997 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYP 1728 G SLKA+ VI + K + +L + F+N T+ +A F+ + ++ I PV K YP Sbjct: 998 GHSLKAMTVIFQVSKALEVDLPVKALFENPTVSELAAFLSKSGKSKYTAIQPVEVKEFYP 1057 Query: 1729 TSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN 1788 S AQKR++ LQ + YN S ++LLEG ++ R ++ RHE+LRTSF + Sbjct: 1058 VSSAQKRMYILQQFEGSGISYNISGAMLLEGKLDYDRFANTVKRLAERHEALRTSFHRID 1117 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE VQ +H V+ ++ E E+ + F++PFDL APLIR GL+Q GE + + ++ Sbjct: 1118 GEPVQKVHEEVEVPILMLTSTEDKAEQIMRDFVRPFDLGIAPLIRTGLVQLGEDRHLFML 1177 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 DMHHII+DG S +L+++FA LY G+ L PL++QYKD+A WQ ++ Y+ +E +WL Sbjct: 1178 DMHHIISDGVSSQILLSEFAKLYQGEALQPLSLQYKDFAAWQNELFQTDVYKKQELHWLN 1237 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 A +P+L LPTDYPRP SF G + + + +ER++K + + T +M + Sbjct: 1238 TFADEIPLLNLPTDYPRPTIQSFAGDLVLFDTGKELTERLRKVAGDTSTTLYMVLLAAYH 1297 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 SG+ DI++G P AGR+H DV+ ++G+FVN+L +RNQP K F FLQEV Sbjct: 1298 VLLSKYSGQEDIIVGTPVAGRSHADVESIMGIFVNTLAMRNQPVS----DKTFTQFLQEV 1353 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 + + L A +NQD+ E +V++L +RD R L+DT+F+ ++ Q+ + + + Sbjct: 1354 KQNALAAYDNQDYPFEELVEKLAIQRDISRNPLFDTMFSLENANQQSLK----IEQLTAA 1409 Query: 2089 PYPMTSKTTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGR 2148 PY + +K +K DL ++ E S I+ + + T LF +ET+Q + Y ++ I Q Sbjct: 1410 PYELFNKISKFDLALNASESQSDIHFQFAFGTKLFAKETIQKMAHHYLEILRTICAQPNA 1469 Query: 2149 TIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQRFEKQVAAYPAHTAVKYREE 2208 + E+ + + + NV+ F + L Q FE+QV P AV Y Sbjct: 1470 KLAEIDMMTEAEKRALLLNVN-----DTFVERSADQVLHQLFEEQVVLTPDQVAVAYDGY 1524 Query: 2209 SLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDR 2268 +L YRQLN +AN++AR + Q + + ++ +IEMV ++ +KAG + P+D Sbjct: 1525 TLTYRQLNARANQVARMLRSKGTQP--DTLIGIMVDRSIEMVVSMLAVLKAGGAYTPMDP 1582 Query: 2269 SAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNT-AEGLSGVSAENPSV 2327 + P +R+ +M++D++A ++LT R L E V I++ E + N Sbjct: 1583 TYPPERIQYMLSDSKAPILLTQ-------RHLKETVEYTGEIIDVDDEAIYAGDDTNLDN 1635 Query: 2328 CPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIG 2387 D A+++YTSGS+G PKGV+ S++ I ++ ++ + +D + T +S Sbjct: 1636 VAGRDDLAYVIYTSGSTGNPKGVMISHQAICNHMLWMKNAFPLLTEDAVLQKTPFSFDAS 1695 Query: 2388 ILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKL 2447 + + L+ GA L L I ++ + E IT VPS+ +M PG Sbjct: 1696 VWEFYLPLITGARLVLAKPDGHRDIAYMTRMIREEKITTLQMVPSLLDLIMTE-PGWSSC 1754 Query: 2448 PSLRMVLLGGEVVTRADF-ELYKKNCAEHCLFVNFLGCSELMV-ISFYTLDKGSEVNHAR 2505 SL+ V GGE +T A Y+ A+ +N G +E + +++ + E H+ Sbjct: 1755 TSLQRVFCGGEALTAALVSRFYQTQTAQ---LINLYGPTESTIDATYWICPRLPE--HSV 1809 Query: 2506 LPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGA 2565 +P G +D + + +V S + + G+L + L+ GYWN+ +TE F P Sbjct: 1810 IPIGKPIDNVRLYVVNASNQLQPVGVAGELCIAGDGLARGYWNREELTEASFIDNPFEPG 1869 Query: 2566 KRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLD 2625 R+YR+GD R L G +EY GR D Q+KIRG+R++L EIE+ L +I+ +IV A D Sbjct: 1870 SRMYRTGDMVRYLACGNVEYLGRIDHQVKIRGHRIELGEIEARLLQHEWIKTAIVLARPD 1929 Query: 2626 HEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPA 2685 +G+ + AY V + D+ L LP+Y++P Y++ L+ P+T KVDR ALP Sbjct: 1930 EKGQNNLYAYIVSDQEMKTADLRAYLASHLPSYMVPSYFVYLEKLPLTANGKVDRKALPQ 1989 Query: 2686 PDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNL 2745 P+ ++++ YV PRNE+E L +W VLG I V D FFE+GGHSL M V + + Sbjct: 1990 PEGASTSEIV--YVAPRNEVEATLVDIWQSVLGQNPIWVHDHFFELGGHSLKAMNVISLI 2047 Query: 2746 EKELKLTVEMGDLFKYPTISSLATFL 2771 + L++ V + LF+ PTI+ L+ ++ Sbjct: 2048 HRTLQVDVPLKTLFESPTIADLSAYI 2073 Score = 644 bits (1662), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/1162 (33%), Positives = 632/1162 (54%), Gaps = 61/1162 (5%) Query: 1627 RPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAIHVISSIRKQFD 1686 RP YV + E +L I+E+ LG IG+ D+FF+L G SLKA+ + + I +++ Sbjct: 3031 RPVTGAEYVAPASPLESRLVEIWEHVLGVTDIGVLDNFFQLGGHSLKAMSLAAQIHREYQ 3090 Query: 1687 CNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLAQKRIFFLQGLMPDT 1746 L L+ F TI+++A +I + + I P + +YP S AQKR+F L+ + Sbjct: 3091 VELPLSVLFATPTIQALASYIETSGKDTHVPIHPAPWQEYYPVSSAQKRMFVLRQFEGTS 3150 Query: 1747 VGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIVQIIHPHVDFKLIRT 1806 YN + + +EG+++ R E ++I RHESLRTSF NGE VQ +H V+ + Sbjct: 3151 TVYNMPSVMFIEGDLDHARFETAIQELIKRHESLRTSFHTVNGEPVQRVHEAVELNVRYE 3210 Query: 1807 AVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIADGTSVNLLVND 1866 + E +E+ +E F+Q FDL +APL+RVGL + E + + ++DMHHII+DG SV +++ + Sbjct: 3211 DLTEDQVEQTIETFVQAFDLEKAPLLRVGLFRLAENRHLFLMDMHHIISDGVSVGIIMEE 3270 Query: 1867 FADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYPRP 1926 F+ Y ++LP L+IQYKD+A WQ ++ Y E YWL+ AG +PVL LP DY RP Sbjct: 3271 FSKFYRNQLLPELSIQYKDFAVWQTDLFQTDIYTKHENYWLKSFAGDIPVLNLPADYSRP 3330 Query: 1927 AALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGIPQ 1986 SF+G I+ D+ + + K + E Q T FM + SG+ DI++G P Sbjct: 3331 LVQSFEGDCISFHTDKTLMDDLYKLAHENQTTLFMVLLAAYNVLLSKYSGQEDIVVGTPI 3390 Query: 1987 AGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIEMI 2046 AGR+H DV++++GMFVN+L LRN P + K F AFL++V+ + L+A +QD+ E + Sbjct: 3391 AGRSHADVEKVLGMFVNTLALRNYP----DGTKSFQAFLEDVKQNTLQAYAHQDYPFEAL 3446 Query: 2047 VDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLSPYPMTSK--TTKADLNIH 2104 V++L+ +RD R L+DT+F Q++ + +A L +K Y + K DL + Sbjct: 3447 VEKLEIQRDLSRNPLFDTMFILQNL----DKKAYELDGLKFEAYSGDGQQGNAKFDLTLE 3502 Query: 2105 LYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQND---I 2161 +E +GI+ Y T LF R+T++ + + +++ + + E+ + + + + Sbjct: 3503 AHEDETGIHFSLVYSTKLFHRDTMERMAGHFLQVLRGVIADQTAALHEIDLLGEEEKHLV 3562 Query: 2162 PPAGGNVSPPVRFQAFHYNDPAENLVQR-FEKQVAAYPAHTAVKYREESLNYRQLNEQAN 2220 A N F A+ P E+ +Q FE+QV P H AV E+ L Y +LN++AN Sbjct: 3563 TVAFNNT-----FAAY----PRESTIQELFEEQVKRTPEHAAVVMNEQMLTYWELNQKAN 3613 Query: 2221 RIARRIWELK-EQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMV 2279 +IA + L+ ++SV V +L ++EM+ + G IKAG ++ +D P +R+ +M+ Sbjct: 3614 QIASVLRRLEVGRDSV---VGMLADRSLEMITGIMGIIKAGGAYLGIDPEHPAERISYML 3670 Query: 2280 NDAQATLILTDSENESIARELAERV-HAKVTIVNTAEGLSGVSAENPSVCPDGDQTAFIL 2338 D ++L + R L V + I+ E L A N + D A+++ Sbjct: 3671 EDGGVKVVL-------VQRHLLHLVEEGLIPIILEDESLEQADASNLTNLNDAKDLAYVM 3723 Query: 2339 YTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIGILDILASLLNG 2398 YTSGS+G PKGV+ +RN+ + + T+ + V +DRM +I +LL+G Sbjct: 3724 YTSGSTGKPKGVMVEHRNVT-RLVKHTNYVQVREEDRMIQTGAIGFDAMTFEIFGALLHG 3782 Query: 2399 ATLHLC--DLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKLPSLRMVLLG 2456 A+L L D+ LDA ++L S+L IT +F L +N P LR +++G Sbjct: 3783 ASLFLVSKDVLLDA--EKLGSFLRENRITTMWLTSPLFNQLSQNNPA--MFEGLRALIVG 3838 Query: 2457 GEVVTRADFELYKKNCAEHCLFV-NFLGCSELMVIS-FYTLDKGSEVNHARLPAGYAVDG 2514 GE ++ + K N A L + N G +E S Y ++K E N +P G + Sbjct: 3839 GEALSPR--HINKVNSAHPALEIWNGYGPTENTTFSTCYLIEKEFEDN---IPIGKPITN 3893 Query: 2515 IDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDY 2574 IV + I G+L + ++ GY N+ +T F P + +YR+GD Sbjct: 3894 STAYIVDRYNQPQPIGVPGELCVGGDGVARGYLNKPELTAEKFVPNPFVLGENMYRTGDL 3953 Query: 2575 GRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAA 2634 R +G +EY GR D Q+KIRGYR++L EIE+ L ++ +++++VT D G++A+ A Sbjct: 3954 ARWKADGTIEYLGRIDQQVKIRGYRIELGEIETVLTNLEKVKEAVVTVLDDTNGQKALCA 4013 Query: 2635 YYVLKEPAAEKDIIRL---LREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAP--DAI 2689 Y+V +E E D++ L + ++LP+Y++P ++++++ P+T KV+R ALP P D + Sbjct: 4014 YFVSEE---ELDVVELREAISKELPSYMVPAFYVQMEKLPLTANGKVNRRALPEPSGDRV 4070 Query: 2690 PSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKEL 2749 + YV P+N E LA +W EVLGI IG+ D FFE+GGHSL M V + K Sbjct: 4071 QGST----YVAPQNATEQKLAEIWQEVLGIHPIGIHDNFFELGGHSLKAMNVITQVHKAF 4126 Query: 2750 KLTVEMGDLFKYPTISSLATFL 2771 ++ + + LF+ PTI LA ++ Sbjct: 4127 QVELPLKALFETPTIHELAAYI 4148 Score = 629 bits (1621), Expect = e-177, Method: Compositional matrix adjust. Identities = 375/1175 (31%), Positives = 629/1175 (53%), Gaps = 47/1175 (4%) Query: 1618 PVTRKSQGKRPELP---------VAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELS 1668 P+T + R LP + YV + E L I+++ LG PI + D FFEL Sbjct: 1975 PLTANGKVDRKALPQPEGASTSEIVYVAPRNEVEATLVDIWQSVLGQNPIWVHDHFFELG 2034 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYP 1728 G SLKA++VIS I + ++ L F++ TI ++ +I A + I PV + +Y Sbjct: 2035 GHSLKAMNVISLIHRTLQVDVPLKTLFESPTIADLSAYIATAGKGKYTTIEPVQKQEYYS 2094 Query: 1729 TSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN 1788 S AQKR+F L+ + + YN + ++G ++ R+++ ++ RHESLRTSF + Sbjct: 2095 VSSAQKRMFILRQMEGAGISYNMPGILYIDGKLDTERLQQALKSVVRRHESLRTSFHSMK 2154 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE VQ +H V+ + E +++ VE+FIQPFDL +APL+R GL++ ++ + ++ Sbjct: 2155 GETVQRVHEDVELDISLMESTEGELKQIVEQFIQPFDLEKAPLMRAGLVKLAPERHLFML 2214 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 D+HHI+ DG S+ +LV + A LY G+ LP L+IQYKD+A WQ + ++ + ++E YW++ Sbjct: 2215 DLHHIVVDGVSIGILVQELAQLYHGEELPELSIQYKDFAHWQNQWYETDEFTAQEAYWID 2274 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 G +PVL L TDYPRP+ SF+G R+ + + + + T +M + Sbjct: 2275 TFTGEIPVLNLATDYPRPSVKSFEGERLVFGSGALLKKELNRLAHSTGATLYMVLLAAYH 2334 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 SG+ DI++G P AGR+H + ++GMFVN+L LRN+P K FL+FL EV Sbjct: 2335 VLLSKYSGQEDIVVGAPTAGRSHAETDSIIGMFVNTLALRNEPVGT----KTFLSFLAEV 2390 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 + + L+A ENQD+ ++ ++D+L+ +RD R L+DT+F Q+M +Q E + + + Sbjct: 2391 KNNTLKAFENQDYPLDELIDKLNIQRDLSRNPLFDTVFILQNM-DQKPFE---MEQLTFT 2446 Query: 2089 PYPMTSKTTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGR 2148 PY K DL++ YE I Y T LF R+T++ I + R++ A+ EQ Sbjct: 2447 PYMAEVNQAKFDLSLEAYEEDEEIVFSLDYCTKLFTRKTIENIAAHFIRILHAVIEQQAI 2506 Query: 2149 TIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPA-ENLVQRFEKQVAAYPAHTAVKYRE 2207 + E+ + A V F H P + L + FE+QV P A++ Sbjct: 2507 PLSEITMLS------AEEKHRLLVEFNQMHKEYPQNKTLHELFEEQVEKTPLVAAIEIGG 2560 Query: 2208 ESLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLD 2267 + ++YR+LNE+AN++A + E + + + V ++ ++EMV + +KAG +VP+D Sbjct: 2561 KQMSYRELNERANQLAVTLRERGVKAN--QFVGIMANRSMEMVVGIMAILKAGGAYVPID 2618 Query: 2268 RSAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAENPSV 2327 P R+ +M+ D +A L+LT ++ + +LA V + + S + N Sbjct: 2619 PEYPEDRVAYMLEDCEARLVLT---HKHLGAKLASSVRVECLYLEEEHNYSP-NRSNLEP 2674 Query: 2328 CPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIG 2387 A+++YTSG++G PKGV+ +R I + + QDR + +++ Sbjct: 2675 IQTASDLAYLIYTSGTTGKPKGVMIEHRGIVNSVLWKKEEYQFSVQDRNLVPLSFAFDGF 2734 Query: 2388 ILDILASLLNGATLHLC---DLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGD 2444 +L +L+G+T L + K S++RL + +T VPS+F+ +++ Sbjct: 2735 VLSFFTPILSGSTAVLVKDEEAKDPLSLRRLIAAARCTQMT---CVPSLFQAILE-CGSA 2790 Query: 2445 VKLPSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMVISFYTLDKGSEVNHA 2504 + SL+ V LGGE V+ E K + + N G +E V++ T + S+++ + Sbjct: 2791 ADISSLQTVTLGGEKVSAQLVEKSNKQNPQ-LVIANEYGPTESSVVA--TWQRISQLD-S 2846 Query: 2505 RLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSG 2564 + G + + IV + + I VG++ L+ GYWN+ +T F S P Sbjct: 2847 TITIGRPIANTSIYIVDKFHQLQPIGVVGEICIGGHGLARGYWNKPELTAEKFVSHPYLE 2906 Query: 2565 AKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATL 2624 +R+Y++GD G+ LP+G +E+ GR D Q+K+RGYR+++ EIES + + ++V Sbjct: 2907 GERMYKTGDLGKWLPDGTIEFIGRLDEQVKVRGYRIEIGEIESVMLSYEKLISAVVIVHE 2966 Query: 2625 DHEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALP 2684 D +G+ ++AAYY +E + L + LP+Y+IP + ++L F P+T K+DR ALP Sbjct: 2967 DQQGQSSLAAYYTAEEKLEVSKLWSYLSKSLPSYMIPAHLVQLDFLPLTPNGKLDRKALP 3026 Query: 2685 APDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNN 2744 P+ P EYV P + +E+ L +W VLG+ IGV D FF++GGHSL M + Sbjct: 3027 KPEGRPVTG--AEYVAPASPLESRLVEIWEHVLGVTDIGVLDNFFQLGGHSLKAMSLAAQ 3084 Query: 2745 LEKELKLTVEMGDLFKYPTISSLATFL----KDKH 2775 + +E ++ + + LF PTI +LA+++ KD H Sbjct: 3085 IHREYQVELPLSVLFATPTIQALASYIETSGKDTH 3119 Score = 625 bits (1612), Expect = e-176, Method: Compositional matrix adjust. Identities = 376/1169 (32%), Positives = 610/1169 (52%), Gaps = 48/1169 (4%) Query: 1616 PEPVTRKSQGKRPELPVAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGDSLKAI 1675 PEP + QG YV TE+KL I++ LG PIGI D+FFEL G SLKA+ Sbjct: 4063 PEPSGDRVQGS------TYVAPQNATEQKLAEIWQEVLGIHPIGIHDNFFELGGHSLKAM 4116 Query: 1676 HVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPTSLAQKR 1735 +VI+ + K F L L F+ TI +A +I + I PV YP S AQKR Sbjct: 4117 NVITQVHKAFQVELPLKALFETPTIHELAAYITASEMEQFETIQPVEHADFYPVSFAQKR 4176 Query: 1736 IFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAENGEIVQII 1795 ++ L + YN ++++G+++ R E ++ RHESLRTSF ++NGE VQ + Sbjct: 4177 MYILHEFEGSGISYNVPNVMIIDGHLDYERFEYAIRTLVKRHESLRTSFHSKNGEPVQRV 4236 Query: 1796 HPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVVDMHHIIA 1855 H V + + + +E+ ++ +QPFDL APL RV L++ G ++ + +DMHHII+ Sbjct: 4237 HEDVTLLIGISEATDDQVEQRIQELVQPFDLEVAPLFRVDLIKLGAERHLFFMDMHHIIS 4296 Query: 1856 DGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLEKLAGPLP 1915 DG S+ ++ +FA LY LP + IQYKD+A WQ SE ++ +E YW AG LP Sbjct: 4297 DGVSLAVIAKEFASLYEKNQLPDMRIQYKDFAAWQTKLAQSERFQKQEDYWTNVFAGELP 4356 Query: 1916 VLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXXXXXXXXS 1975 +L LP D+PRP SF+G + + +++ + T FM + + Sbjct: 4357 LLNLPNDFPRPTVQSFEGDTVAIGTGNHLLAELRQLAANTGSTLFMVLLAAYNVLLSKYT 4416 Query: 1976 GESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEVRASLLEA 2035 G+ +I++G P AGR+H DV+ +VGMFVN+L L+N F FL +V+ + L A Sbjct: 4417 GQEEIVVGTPIAGRSHADVERIVGMFVNTLALKNVAGGDL----TFREFLGDVKQNALHA 4472 Query: 2036 LENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLSPYPMTSK 2095 E+QD+ E +VD+L +RD R L+DT+F+ ++ A + + +S YP+ K Sbjct: 4473 FEHQDYPFEHLVDKLQVRRDLSRNPLFDTMFSL----GLADSSALEIAGLNMSAYPVDGK 4528 Query: 2096 TTKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPV 2155 K D+ + E + V+ Y T LF +E++ + Y L++ I R + E+ V Sbjct: 4529 IAKFDIALDAMEQQDELLVQFSYCTKLFAKESIDRMATHYIHLLQTIIANPDRKLAEISV 4588 Query: 2156 FRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQR-FEKQVAAYPAHTAVKYREESLNYRQ 2214 ++++ + F A + P Q FE+QV P AV +E L YR+ Sbjct: 4589 LSKDEMEQMLHD------FNATNVAYPTNKTFQELFEEQVEKTPNQVAVICEDEQLTYRE 4642 Query: 2215 LNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQR 2274 LNE+AN++AR + ++ + E V ++ ++ MV G +KAG +VP+D PL+R Sbjct: 4643 LNEKANQLARVLRQMGVKP--ESTVGIMVDRSLHMVVGTLGILKAGGAYVPIDPDYPLER 4700 Query: 2275 LIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAENPSVCPDGDQT 2334 ++ D+ A L LT + + + V T+ AEGL A N + Sbjct: 4701 QAFILEDSDAKLFLT------LQKMNTQLVFPYETLYLDAEGLYQGEASNLEPVALPEHA 4754 Query: 2335 AFILYTSGSSGIPKGVV---QSYRNIAFYIAQFTH--SLAVNHQDRMALLTTYSHAIGIL 2389 A+I+YTSG++G PKGVV +SY N+AF H + V R+ + +++ + Sbjct: 4755 AYIIYTSGTTGKPKGVVIEHRSYANVAFAWQDEYHLDTFPV----RLLQMASFAFDVSTG 4810 Query: 2390 DILASLLNGATLHLC--DLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNL-PGDVK 2446 D +LL G L +C ++K+D + L + IT++ + P++ LM + + Sbjct: 4811 DFARALLTGGQLVICPNEVKMDPA--SLYEIIKRYEITIFEATPALIMPLMHYIYENKLD 4868 Query: 2447 LPSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMV-ISFYTLDKGSEVNHAR 2505 + +++++LG + + DF+ + VN G +E + S+Y S + Sbjct: 4869 ISQMKLLILGADSCSAEDFKTLLTRFSHTLRIVNSYGVTEACIDSSYYEETDVSSIRSGT 4928 Query: 2506 LPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGA 2565 +P G + + + ++ + + VG+L ++ GY N+ +T F P + Sbjct: 4929 VPIGKPLPNMQMYVMDQQLNLQPVGVVGELCIGGAGVARGYLNRPELTVEKFVPNPFAPG 4988 Query: 2566 KRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLD 2625 + LYR+GD + +G +E+ GRND Q+KIRG R++L EIE+ L + I +++V A D Sbjct: 4989 ELLYRTGDLAKWRADGNMEFLGRNDHQVKIRGVRIELGEIETQLRKLDGILEAVVVARED 5048 Query: 2626 HEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPA 2685 H E+ + AY V + + L ++LP +IP Y++ L+ P+T K+DR +LP Sbjct: 5049 HRQEKYLCAYMVADHEIDTAQVRKQLLKELPQAMIPSYFVTLEALPLTANGKIDRRSLPV 5108 Query: 2686 PDAIPSNDLR-HEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNN 2744 PD + LR EYV PR E+E LAR+W +VL ++ +GV D FF IGGHSL M V ++ Sbjct: 5109 PDV---SLLRTTEYVAPRTELEAQLARVWEQVLNVEQVGVLDDFFAIGGHSLRAMSVISS 5165 Query: 2745 LEKELKLTVEMGDLFKYPTISSLATFLKD 2773 + E ++ + + LF+ PTI LA ++++ Sbjct: 5166 MHNEYQVDIPLRVLFEKPTIQQLAAYIEE 5194 Score = 609 bits (1570), Expect = e-171, Method: Compositional matrix adjust. Identities = 393/1188 (33%), Positives = 623/1188 (52%), Gaps = 73/1188 (6%) Query: 1618 PVTRKSQGKRPELPV---------AYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELS 1668 P+T + R LPV YV T+ E +L ++E L + +G+ DDFF + Sbjct: 5094 PLTANGKIDRRSLPVPDVSLLRTTEYVAPRTELEAQLARVWEQVLNVEQVGVLDDFFAIG 5153 Query: 1669 GDSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYP 1728 G SL+A+ VISS+ ++ ++ L F+ TI+ +A +I ++ I P + +YP Sbjct: 5154 GHSLRAMSVISSMHNEYQVDIPLRVLFEKPTIQQLAAYIEETAKEYVISIKPAPAQGYYP 5213 Query: 1729 TSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAEN 1788 S AQKR++ L + YN +++L+EG + R+E F Q+I RHESLRTSF N Sbjct: 5214 VSSAQKRMYILHQFEGVGISYNMPSTMLIEGKLEPERLETAFKQLIARHESLRTSFAVVN 5273 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE VQ IH V F+L T + E +E + +QPFDL APL+RV LLQ GE + +L Sbjct: 5274 GEPVQKIHEEVSFELSYTTITEDQAQEVLSSLVQPFDLGVAPLLRVRLLQIGEDRHVLFT 5333 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 D HH I+DG S +L++D LY G +LP L IQY+D++ WQQ S+A+ +E YW + Sbjct: 5334 DTHHSISDGVSSGILLSDLVQLYQGDVLPELRIQYRDFSVWQQELFRSDAFNKQEHYWAQ 5393 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 A +PVL L TD+ RP+ +F G + ++ + E + + ++E T +M + Sbjct: 5394 VFADEIPVLNLQTDFTRPSIQNFAGDQYSIGTGKQLMEGLNQLARETGTTLYMVLLATYN 5453 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 SG+ DI++G P GR+H D++ +VGMFVN+L +RN+P K F L EV Sbjct: 5454 VLLSKYSGQEDIIVGTPITGRSHADLEPIVGMFVNTLAMRNKPHA----GKTFTELLLEV 5509 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 + + L+A +QD+ E +V++LD RD R L+DT+F Q+ + A LH + L+ Sbjct: 5510 KQNALDAYAHQDYPFEELVEKLDIPRDLSRNPLFDTMFTVQNNSDN----AIDLHGLTLA 5565 Query: 2089 PYPMTSKT---TKADLNIHLYEVPSGIYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQ 2145 P+ MT + +K DL + E I + Y T LF RET++ + + + + + + Sbjct: 5566 PF-MTDQAGNHSKFDLTLIATEEREEIRIGVEYSTSLFTRETIERLSNHFMAIAQIVVQN 5624 Query: 2146 AGRTIGELPVFRQNDIPPAGGNVSPPVRFQAFH-YNDPAENLVQR------FEKQVAAYP 2198 + E+ + + + + Q F +ND A N VQ FE+QVA P Sbjct: 5625 PHIRLSEIDMLKAEE------------KKQIFESFNDTAVNYVQDKTLHQLFEEQVAKTP 5672 Query: 2199 AHTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIK 2258 A+ + +SL Y +LNEQANR+AR + + +R VA++ + EM+ + G +K Sbjct: 5673 NQEAILFNGQSLTYSKLNEQANRLARVLR--TKGVGPDRLVAVMAERSPEMIIGILGILK 5730 Query: 2259 AGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVN-TAEGL 2317 AG +VP+D + P +R+ +++ D+ A L+L S EL RV + + + +A+ Sbjct: 5731 AGGAYVPIDPAYPQERIQYLLADSNAALLLCQSH----LSELLSRVSSGLDWLELSAKHD 5786 Query: 2318 SGVSAENPSVCPDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMA 2377 + N S A+++YTSG++G PKGV+ +R I + D+ Sbjct: 5787 VEIDGSNLSSLNQPTDLAYVIYTSGTTGKPKGVMIPHRGIVNCLQWRRDEYGFGPGDKAL 5846 Query: 2378 LLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFL 2437 + +++ + + A LL GAT L + L + S G+T Y+ VPS+F+ + Sbjct: 5847 QVFSFAFDGFVASLFAPLLGGATCVLPREEEAKDPVALKKLIASAGVTHYYGVPSLFQAI 5906 Query: 2438 MKNLPGDVKLPSLRMVLLGGEVVTRADFELYKKNCAEH--CLFVNFLGCSELMVISFYTL 2495 + + LR V LGGE + +L +K +H N G +E V++ T+ Sbjct: 5907 L-DCSTAADFSPLRCVTLGGE---KLPAQLVQKTKEKHPAIEINNEYGPTENSVVT--TI 5960 Query: 2496 DKGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTER 2555 + E + G + + V IV I VG+L L+ GY N+ +T+ Sbjct: 5961 SRSIEAGQ-DITIGRPLANVQVYIVDTQHHLQPIGVVGELCIGGPGLAKGYLNKPELTQE 6019 Query: 2556 VFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFI 2615 F P + +Y++GD + +G ++Y GR D Q+K+RGYR+++ EIEST+ I Sbjct: 6020 KFVPNPFVPGELMYKTGDLVKWRADGTIDYIGRADEQVKVRGYRIEIGEIESTILAYDGI 6079 Query: 2616 QQSIVTATLDH-EGEQAIAAYYVLKEPAAE---KDIIRLLREQLPAYLIPRYWIELKFFP 2671 Q++V D Q + AY V PAAE ++ R L ++LPAY++P Y+++L P Sbjct: 6080 DQAVVVVQEDELTAGQYLCAYLV---PAAEVSVSELRRHLTKELPAYMVPSYFVQLDQLP 6136 Query: 2672 MTGPNKVDRNALPAPDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEI 2731 ++ KVDR ALP P PS+ E+V PR +E LA +W EVLGI IG+ D FFE+ Sbjct: 6137 LSANGKVDRKALPKPK--PSDATTREFVAPRTAIEYQLAAIWQEVLGIDPIGITDHFFEL 6194 Query: 2732 GGHS----LLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFLKDKH 2775 GGHS LL+ +V ++ EL L + +F++PTI +A F+ K+ Sbjct: 6195 GGHSLKATLLVAKVYEYMQIELPLNL----IFQHPTIEKVADFITHKN 6238 Score = 298 bits (763), Expect = 7e-78, Method: Compositional matrix adjust. Identities = 263/1084 (24%), Positives = 494/1084 (45%), Gaps = 97/1084 (8%) Query: 1727 YPTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRA 1786 YP + Q+ + F + Y S L+G+ E+ ++I +E LRT F Sbjct: 11 YPLTPLQEGMLFHAVKDTGSSAYCLQMSAKLQGDFQLSIFEKSMNKLIENYEVLRTVFVY 70 Query: 1787 ENGEIVQIIHP-HVDFKLIRTAVKEQGIE-----------EAVERFIQPFDLARAPLIRV 1834 +N + P V FK + V + I +A F+L + L++ Sbjct: 71 QN-----LQRPRQVVFKERKVTVHFENIAHLPIDDQNDYIKAYTNQQHTFELTKDVLMKA 125 Query: 1835 GLLQAGEQQSILVVDMHHIIADGTSVNLLVND----FADLYMGKILPPLAIQ-YKDYAEW 1889 + Q Q V HHII DG S+ +L++ +A + G+ +P A + Y +Y +W Sbjct: 126 AIFQTEANQYQFVWAFHHIIVDGWSLGVLLHKLLGYYAAIRKGEAVPREATKPYSEYIKW 185 Query: 1890 QQGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYPRPAALSFQGGRITLE----LDRPSS 1945 EA TYW + L G D+P+ ++ G + +E + + Sbjct: 186 LDKQNKEEAL----TYWQKYLEG----YDHQADFPKKKNVAEDGNYVHVENLFTIAPEKT 237 Query: 1946 ERIKKFSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGIPQAGR--NHEDVQEMVGMFVN 2003 +++ + + Q T D++ G +GR + ++ MVG+F+N Sbjct: 238 QQLMQIANRNQATMSSVFQSLWGILASKYKNSDDVVFGSVVSGRPPGIQGIESMVGLFIN 297 Query: 2004 SLVLRNQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYD 2063 ++ R Q RK+ F ++ V+ L + + I + K++ L D Sbjct: 298 TIPTRVQ----TNRKQTFSGLVKTVQKQALASAAYDFAPLYEIQSKTVLKQE-----LID 348 Query: 2064 TIFNYQSM----KNQTETEASYLHDMKLSPYPMTSKTTKADLNIHLYEVPSG-IYVECFY 2118 + Y++ N E + +++ + T D N+ + PS +YV+ Y Sbjct: 349 HLVTYENYPDDASNDREDSLGFQFNVENG-----EEQTSYDFNVVVAVAPSNEMYVKLSY 403 Query: 2119 RTDLFKRETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDIPPAGGNVSPPVRFQAF- 2177 +++ + + + +IE + P NDI G ++ + Q Sbjct: 404 NAAVYEESFMNRVEGHLKTIIEQVIHN--------PNVLLNDI----GIITDEEKQQLLV 451 Query: 2178 HYNDPA------ENLVQRFEKQVAAYPAHTAVKYREESLNYRQLNEQANRIARRI-WELK 2230 YND + + + +Q P+ AV E+ L Y++L E++N++AR + + Sbjct: 452 AYNDTTADYPRDKTIFELIAEQARQTPSKAAVICGEDRLTYQELQERSNQLARALRGKGI 511 Query: 2231 EQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTD 2290 Q S+ V+++ +++E++ A+ +K+G ++P+D P++R+ ++++D+Q ++LT Sbjct: 512 TQGSI---VSIMAEHSLELIVAIMAVLKSGGAYLPIDPEYPIERIQYLLDDSQTKILLTQ 568 Query: 2291 SENESIARELAERVH--AKVTIVNTAEGLSGVSAENPSVCPDGDQTAFILYTSGSSGIPK 2348 S L E+V + ++ G S + + C D A+++YTSGS+G PK Sbjct: 569 SH-------LQEKVEFEGDILYLDNPSLFEGDSTDLDNSC-KPDDLAYMIYTSGSTGNPK 620 Query: 2349 GVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHAIGILDILASLLNGATLHLCDLKL 2408 G + +++ + YI L ++ S + I I LL+G T+++ + Sbjct: 621 GAMITHQGLVNYIWWANKEYVQGEAVDFPLYSSISFDLTITSIFTPLLSGNTIYVY--RG 678 Query: 2409 DASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDVKLPSLRMVLLGGEVVTRADFELY 2468 +Q + + + + P+ + L++ + G S+R ++GGE + + Sbjct: 679 ADKVQVILDIIQDNQVGIIKLTPTHLK-LIEEIDGTNS--SIRRFIVGGENLPTKLAKRI 735 Query: 2469 KKNCAEHCLFVNFLGCSELMV-ISFYTLDKGSEVNHARLPAGYAVDGIDVRIVGESGREA 2527 +N ++ N G +E +V Y D + + +P G D + + ++ S + Sbjct: 736 YENFGQNVKIFNEYGPTETVVGCMIYLYDPKKPIQES-VPIGVPADNVQLYLLDSSMQPI 794 Query: 2528 GIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHG 2587 + G++ + ++ GY+N+ +TE F P ++YR+GD + LP+G +EY G Sbjct: 795 PVGSAGEMYIAGDGVAKGYFNRPELTEEKFIDNPFRPGTKMYRTGDLAKWLPDGNMEYVG 854 Query: 2588 RNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLDHEGEQAIAAYYVLKEPAAEKDI 2647 R D Q+KIRG+R+++ EIE+ L +I++++V A D G+ + AY V ++ ++ Sbjct: 855 RIDHQVKIRGHRIEMGEIETRLAQHEWIKEAVVIAEKDDSGQNVLYAYMVSEQELTVSEL 914 Query: 2648 IRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPAPDAIPSNDLRHEYVPPRNEMEN 2707 L LP+Y+IP +++ L+ P+T KV+R LP PD YV P+NE E Sbjct: 915 REHLGSTLPSYMIPSFFVRLEEIPLTANGKVERKKLPKPDGAVVTGT--AYVAPQNETET 972 Query: 2708 MLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSL 2767 LA +W +VLG+ +GV D FF++GGHSL M V + K L++ + + LF+ PT+S L Sbjct: 973 KLAEIWQQVLGVSRVGVHDHFFDLGGHSLKAMTVIFQVSKALEVDLPVKALFENPTVSEL 1032 Query: 2768 ATFL 2771 A FL Sbjct: 1033 AAFL 1036 >O30981.1 O30981_BACSU Fengycin synthetase FenE Length = 2554 Score = 665 bits (1715), Expect = 0.0, Method: Compositional matrix adjust. Identities = 407/1167 (34%), Positives = 632/1167 (54%), Gaps = 43/1167 (3%) Query: 1618 PVTRKSQGKRPELPV--------AYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSG 1669 PVT + R LP Y TE KL ++E L P+GI D+FF+ G Sbjct: 938 PVTPSGKLDRKALPAPDGAADRETYTAPRNLTEMKLSQLWEEVLKSGPVGIHDNFFDRGG 997 Query: 1670 DSLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQIAPVNPKSHYPT 1729 SLKA ++S I K+F + L D F + T++ +A I + + I P + YP Sbjct: 998 HSLKATALVSRIAKEFGVQVPLKDVFAHPTVEGLASVISEGTESPYEAIKPAGKRETYPV 1057 Query: 1730 SLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRAE-N 1788 S AQKR++ LQ L GYN + LEG ++ R++ VF ++I RHESLRTSF + + Sbjct: 1058 SSAQKRMYVLQQLEDGGTGYNMPAVLELEGKLDLTRMDAVFKKLIKRHESLRTSFTTDTD 1117 Query: 1789 GEIVQIIHPHVDFKLIRTAVKEQGIEEAVERFIQPFDLARAPLIRVGLLQAGEQQSILVV 1848 GE VQ IH V F+ + + Q +EA FIQPFDL++APL R G+++ + + +L+V Sbjct: 1118 GEPVQRIHDEVPFRFHTSVLGGQTEQEAASAFIQPFDLSQAPLFRAGIVKVSDGRHLLLV 1177 Query: 1849 DMHHIIADGTSVNLLVNDFADLYMGKILPPLAIQYKDYAEWQQGFITSEAYRSKETYWLE 1908 DMHHII+DG SVN L+ +F +LY + LP L IQYKDYA WQ+ F E Y+++E YWL+ Sbjct: 1178 DMHHIISDGVSVNTLIREFGELYANQELPALHIQYKDYAVWQEAFKKGETYKTQEAYWLK 1237 Query: 1909 KLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKKFSQEQQVTWFMTMXXXXX 1968 +L G LPVL LP DY RP +F G +++ LD+ + + K ++E T +M + Sbjct: 1238 QLEGELPVLDLPADYARPPVRTFAGDQVSFTLDQELTAGLHKLARENGSTLYMVLLAAYT 1297 Query: 1969 XXXXXXSGESDILIGIPQAGRNHEDVQEMVGMFVNSLVLRNQPXXXXERKKPFLAFLQEV 2028 SG+ DI++G P AGR H+D++ ++GMFVN+L LR +P E KPF FLQEV Sbjct: 1298 ALLARLSGQEDIIVGSPIAGRPHKDLEPILGMFVNTLALRARP----EGGKPFAQFLQEV 1353 Query: 2029 RASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNYQSMKNQTETEASYLHDMKLS 2088 R + LEA E+QD+ E +VD+L RD R L+D +F Q+M + E+ L D+ L Sbjct: 1354 RETALEAYEHQDYPFEELVDKLGMTRDMSRNPLFDVMFVLQNM----DQESMQLKDLCLR 1409 Query: 2089 PYP-MTSKTTKADLNIHLYEVPSG-IYVECFYRTDLFKRETVQYIFEEYRRLIEAIPEQA 2146 P + + +K DL ++ YE +G + + Y TDL+++ T++ ++ AI + + Sbjct: 1410 PATNVEHQVSKFDLTLYAYEEANGSMMFQMEYSTDLYQKNTIEMWLHYLMNMLRAIIQDS 1469 Query: 2147 GRTIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPAENLVQRFEKQVAAYPAHTAVKYR 2206 +G + V +N+ ++ R H E + + FE Q A P AV Sbjct: 1470 EAALGTIHVLDENETHFLIHELNCTKREYPRH-----ETISRLFELQAAQTPDAIAVAGD 1524 Query: 2207 EESLNYRQLNEQANRIARRIWELKEQESVERPVALLFGNTIEMVAALAGAIKAGIPFVPL 2266 E++L Y++LN +ANRIA + ++ E VALL T E+ A + G +KAG ++P+ Sbjct: 1525 EQTLTYKELNIRANRIAAVL--RRKGVGPETVVALLTTRTPEIAAGMLGILKAGGAYLPI 1582 Query: 2267 DRSAPLQRLIHMVNDAQATLILTDSENESIARELAERVHAKVTIVNTAEGLSGVSAENPS 2326 + P R+ +M++D+ A ++L SE + R E K+ I E + G Sbjct: 1583 AKDLPADRISYMLSDSGAKILL-QSEKANNQRLDLELKCEKIVI----EEIQGQGETKNF 1637 Query: 2327 VCPDGDQT-AFILYTSGSSGIPKGVVQSYRNIAFYIAQFTHSLAVNHQDRMALLTTYSHA 2385 P G + A+I+YTSGS+G PKGV+ R++ + + ++ + +DR+ L ++ Sbjct: 1638 EAPAGPHSLAYIIYTSGSTGKPKGVMIEQRSV-IRLVKNSNYIEFTPEDRLLLTSSLGFD 1696 Query: 2386 IGILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEGITLYHSVPSVFRFLMKNLPGDV 2445 + +IL LLNGA LHL D + +L ++ GIT S+F L + + Sbjct: 1697 VVTFEILGPLLNGAALHLTDKETFLDSHQLKRYIEQNGITTMWLTASLFNHLTEQ--NEK 1754 Query: 2446 KLPSLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFLGCSELMVISFYTLDKGSEVNHAR 2505 L +++GGE ++ + K+ C E ++ N G +E +F T ++ Sbjct: 1755 IFSRLINLIIGGEALSASHVNRIKQACPELSIW-NGYGPTE--NTTFSTCFHIEKLYEHS 1811 Query: 2506 LPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEYLSPGYWNQAGVTERVFASGPDSGA 2565 +P G + I+ + G I VG+L + ++ GY + +T+ F P + Sbjct: 1812 IPIGRPIGNSTAFILNKWGMLQPIGAVGELCVGGDGVARGYLGRPDLTKEKFVPNPFAPG 1871 Query: 2566 KRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVDLNEIESTLDHIPFIQQSIVTATLD 2625 +++YR+GD R LP+G +EY GR D Q+KIRGYRV+L EIES L HI ++++ V A Sbjct: 1872 EQMYRTGDLARWLPDGTIEYVGRVDDQVKIRGYRVELGEIESALRHIDGVKEAAVLARTG 1931 Query: 2626 HEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIPRYWIELKFFPMTGPNKVDRNALPA 2685 G + + AY +KE + + L + LP Y++P Y IE+ P+T K++R ALP Sbjct: 1932 QLGTKELYAYISVKEGTDAEQVRTHLSQMLPGYMMPAYVIEMDALPLTANGKLNRKALPE 1991 Query: 2686 PDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQHIGVDDGFFEIGGHSLLLMQVQNNL 2745 PD + YVPPRN++E LA +W EVLG Q IG++D FFE+GG S+ +QV L Sbjct: 1992 PDITS----KQTYVPPRNDLEEQLAIIWQEVLGTQRIGIEDSFFELGGDSIKALQVSARL 2047 Query: 2746 EKELKLTVEMGDLFKYPTISSLATFLK 2772 + ++ DLF++P I L+ ++ Sbjct: 2048 GR-YGWSLHASDLFRHPKIKDLSAVIR 2073 Score = 322 bits (825), Expect = 4e-85, Method: Compositional matrix adjust. Identities = 275/1072 (25%), Positives = 486/1072 (45%), Gaps = 70/1072 (6%) Query: 1727 YPTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRA 1786 YP S Q+ + F + Y E S + G ++ R ++ + +R+E RT+F Sbjct: 11 YPLSFMQEGMLFHSLYDEQSRAYFEQASFTINGQLDLDRFQKSMDAVFDRYEIFRTTFIY 70 Query: 1787 EN-GEIVQII----HPHVDFKLIRTAVKEQGIEEAVERFIQP-----FDLARAPLIRVGL 1836 +N + Q++ HV F+ I + + E+ E E F + FDL L+R+ + Sbjct: 71 KNVAKPRQVVLKNRSCHVHFEDI-SHLNEREKEHCTEAFKEQDKKRGFDLQSDVLMRISV 129 Query: 1837 LQAGEQQSILVVDMHHIIADGTSVNLLVNDFADLYM----GKI--LPPLAIQYKDYAEWQ 1890 L+ ++ + + HHI+ DG + +++ DF +Y G++ L P+ Y Y +W Sbjct: 130 LKWAPERYVCIWSHHHILMDGWCLGIIIKDFLHIYQALGEGRLPYLQPVQ-PYGTYIKW- 187 Query: 1891 QGFITSEAYRSKETYWLEKLAGPLPVLTLPTDYPRPAALSFQGGRITLELDRPSSERIKK 1950 + + YW ++L +LP + + Q ++T + + ++K Sbjct: 188 ---LMQQDREEAAAYWKKRLQHFEKASSLPKRNEQVSEGELQ--QVTFTISEKETSDLQK 242 Query: 1951 FSQEQQVTWFMTMXXXXXXXXXXXSGESDILIGIPQAGRNHE--DVQEMVGMFVNSLVLR 2008 + T + D + G +GR E DV+ +VG+F+N++ +R Sbjct: 243 IAAASGATLNTVFQALWGILLQKFNRCDDAVFGSVVSGRPSELEDVENIVGLFINTIPIR 302 Query: 2009 NQPXXXXERKKPFLAFLQEVRASLLEALENQDFQIEMIVDQLDYKRDPGRTFLYDTIFNY 2068 Q + F + ++ + EA F + I Q K++ L D I + Sbjct: 303 VQ-----SKALSFSGLVSRMQKEMTEAEAYSYFPLYDIQAQSALKQE-----LIDHIIVF 352 Query: 2069 QSMKNQTETEA---SYLHDMKLSPYPMTSKTTKADLNIHLYEVPS-GIYVECFYRTDLFK 2124 +++ Q E E + + + M +T + + +P ++V + T L++ Sbjct: 353 ENVPTQQEIEGLNQTGSFGFSVENFAMAEET---NYGCSVKVIPGRTLFVRINFHTGLYE 409 Query: 2125 RETVQYIFEEYRRLIEAIPEQAGRTIGELPVFRQNDIPPAGGNVSPPVRFQAFHYNDPAE 2184 + I + + +I A+ + ++ + + + A A Sbjct: 410 PGIIAEIKDYLQHMISAVISDPSLPVSKMTLLDHDKTQKMVAEYNTTGAVSAL-----AP 464 Query: 2185 NLVQRFEKQVAAYPAHTAVKYREESLNYRQLNEQANRIARRIWELKEQESVERPVALLFG 2244 L FE+QVA P TA+++ SL Y QL+ ANR+A R+ + E V +L Sbjct: 465 TLHGLFERQVALTPDRTALRFSGGSLTYAQLDMYANRLAARL--TAHGITKESIVGVLSE 522 Query: 2245 NTIEMVAALAGAIKAGIPFVPLDRSAPLQRLIHMVNDAQATLILTDSENESIARELAERV 2304 + +M+ A+ +KAG +VPLD + P +RL +M+ D+ A L+LT L V Sbjct: 523 RSPDMLTAVLAVLKAGGAYVPLDPAYPEERLSYMLKDSGAALLLTQPG-------LKAPV 575 Query: 2305 HAKVTIVNTAEGLSGVSAENPSVC-PDGDQTAFILYTSGSSGIPKGVVQSYRNIAFYIAQ 2363 + T+ L+ +E S+ D D A+++YTSGS+G PKGV +R ++ Sbjct: 576 FSGKTLEVDMTALANEESECHSLHQADSDSLAYVIYTSGSTGRPKGVAVEHRQAVSFLTG 635 Query: 2364 FTHSLAVNHQDRMALLTTYSHAIGILDILASLLNGATLHLCDLKLDASIQRLSSWLNSEG 2423 + D + + T++S + + L+GA+ +L + + + EG Sbjct: 636 MQMQFPLEEDDIIMMKTSFSFDASVWQLFWWTLSGASAYLLPSGWEKDPALMVKAIREEG 695 Query: 2424 ITLYHSVPSVFRFLMKNLPGDVKLP-SLRMVLLGGEVVTRADFELYKKNCAEHCLFVNFL 2482 +T H +P++ + +++ P SL+ V GGE + + E L V+ Sbjct: 696 VTTAHFIPAMLNSFLDQ--AEIEAPRSLKRVFAGGEPLAPHTAARFASLLPETSL-VHGY 752 Query: 2483 GCSELMV-ISFYTLDKGSEVNHARLPAGYAVDGIDVRIVGESGREAGIFEVGQLVYQSEY 2541 G +E V +FY D + N RLP G V G + ++ + G+L Sbjct: 753 GPTEATVDAAFYACDPELDKNRLRLPIGKPVPGARLYVLDPHLAVQPVGVAGELYIAGAG 812 Query: 2542 LSPGYWNQAGVTERVFASGPDSGAKRLYRSGDYGRLLPNGCLEYHGRNDAQLKIRGYRVD 2601 ++ GY N+ +TE F P +R+Y++GD R LP+G +E+ GR D Q+KIRGYR++ Sbjct: 813 VARGYLNRPELTEERFLDDPFYPGERMYKTGDLARWLPDGQVEFLGRLDDQVKIRGYRIE 872 Query: 2602 LNEIESTLDHIPFIQQSIVTATLDHEGEQAIAAYYVLKEPAAEKDIIRLLREQLPAYLIP 2661 EIE+ L I ++++ VT + GE + AY E ++ + L LP Y+IP Sbjct: 873 PGEIEAALRSIEGVREAAVTVRTE-SGEAELCAY---AEGLGRNEVRKQLETLLPGYMIP 928 Query: 2662 RYWIELKFFPMTGPNKVDRNALPAPDAIPSNDLRHEYVPPRNEMENMLARLWGEVLGIQH 2721 + IE++ +P+T K+DR ALPAPD R Y PRN E L++LW EVL Sbjct: 929 AHIIEMEQWPVTPSGKLDRKALPAPDGAAD---RETYTAPRNLTEMKLSQLWEEVLKSGP 985 Query: 2722 IGVDDGFFEIGGHSLLLMQVQNNLEKELKLTVEMGDLFKYPTISSLATFLKD 2773 +G+ D FF+ GGHSL + + + KE + V + D+F +PT+ LA+ + + Sbjct: 986 VGIHDNFFDRGGHSLKATALVSRIAKEFGVQVPLKDVFAHPTVEGLASVISE 1037 Score = 111 bits (277), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 88/327 (26%), Positives = 147/327 (44%), Gaps = 41/327 (12%) Query: 1618 PVTRKSQGKRPELP-------VAYVPAGTDTEKKLCAIYENHLGFQPIGIEDDFFELSGD 1670 P+T + R LP YVP D E++L I++ LG Q IGIED FFEL GD Sbjct: 1977 PLTANGKLNRKALPEPDITSKQTYVPPRNDLEEQLAIIWQEVLGTQRIGIEDSFFELGGD 2036 Query: 1671 SLKAIHVISSIRKQFDCNLTLTDFFQNKTIKSVARFIRNASRANERQ----IAPVNPKSH 1726 S+KA+ V + + + + +L +D F++ IK ++ IR R ++ P P H Sbjct: 2037 SIKALQVSARLGR-YGWSLHASDLFRHPKIKDLSAVIRKTERVIDQGSVQGAVPWTPIQH 2095 Query: 1727 YPTSLAQKRIFFLQGLMPDTVGYNESTSVLLEGNINAGRIEEVFAQIINRHESLRTSFRA 1786 + FL + + +N+S + ++ + ++ H++LR +R Sbjct: 2096 W----------FLSQDIKERHHFNQSVMLFSPDCLSENALRASLKKLAEHHDALRMIYRE 2145 Query: 1787 ENGEIVQI---IHPHVDFKLIRTAVKEQG------IEEAVERFIQPFDLARAPLIRVGLL 1837 ++G+ +QI IH + L + + + G I+E V Q +L + PL+ Sbjct: 2146 DSGQQMQINQDIHESKLYSLRISDLSDSGMDWETSIKEEVANLQQSINLQQGPLLHAAWF 2205 Query: 1838 QAGEQQSILVVDMHHIIADGTSVNLLVNDFADLYMGKI------LPPLAIQYKDYAEWQQ 1891 + L + +HH++ DG S +L+ D + Y LPP Y++YA Q Sbjct: 2206 KT-LSGDYLFLTIHHLVVDGVSWRILLEDLSAAYHQAASGQAIQLPPKTDSYQEYARRVQ 2264 Query: 1892 GFITSEAYRSKETYWL---EKLAGPLP 1915 + S +ETYW E+ A LP Sbjct: 2265 DYAQSSKLIREETYWRSVEEEKAAELP 2291 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.135 0.397 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 16,510,620,948 Number of extensions: 704623324 Number of successful extensions: 1946741 Number of sequences better than 1.0e-05: 19861 Number of HSP's gapped: 1841284 Number of HSP's successfully gapped: 30266 Length of query: 2806 Length of database: 3,060,696,203 Length adjustment: 154 Effective length of query: 2652 Effective length of database: 1,609,859,893 Effective search space: 4269348436236 Effective search space used: 4269348436236 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 141 (58.9 bits)