BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0012.p (1728 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C2P7V8.1 C2P7V8_BACCE Polyketide synthase type I 1234 0.0 C0JRE5.1 C0JRE5_BACCE ZmaA 1233 0.0 C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I 1232 0.0 C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I 1231 0.0 B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase 1231 0.0 >C2P7V8.1 C2P7V8_BACCE Polyketide synthase type I Length = 3338 Score = 1234 bits (3192), Expect = 0.0, Method: Compositional matrix adjust. Identities = 670/1729 (38%), Positives = 1009/1729 (58%), Gaps = 56/1729 (3%) Query: 11 EIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAGAV 70 +IA+IG+ RFPGA N +FWNN+K G ES+ FTDEEL GV +++ NYVKA Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVNSPNYVKAKGY 1437 Query: 71 LDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGASSN 130 L+ + FD FF Y+P+DA +MDPQ+R+FHE AW +LE AGY +TYPGLIGV++GAS N Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 131 YNWNA-RVYSYEGEHRDAFSEIQLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXIHT 189 W S E F L++KD L+++ISYKFNLKGPSM IH Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 190 ACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGTGA 249 AC++LL G CD+AIAGG ++ P ++GY YQEG S DGH R FDE A+G+LFG+G G Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 250 VVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGPDS 309 VVLKPL+ A+ D D I AV+KG+A+NNDGNRK GY APSVEGQ EVI+ A + V P+S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 310 ISYIETHGTGTQLGDTIEFTALQQVFHTRQSPCI-LGSVKNNIGHLDAASGVAGFMKAVL 368 ISYIETHGT T+LGDTIE AL +VF++ + + +GSVK N+GHL+AASGVAG +K V Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 369 ALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYPLRAGVSSFGVGGMNAHLI 428 A+K + +PP VNF K N + EK PF VN +L +W + PLRAGVSSFG+GG NAH+I Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 429 LEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTLQAGR 488 LE+AP +E Q++++SA+S ++L+ MT NL H+E++P + + D +YTLQ GR Sbjct: 1798 LEEAP-KLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGR 1856 Query: 489 KPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMGRELY 548 K F+ R+ L+C ++ IE L + D R+ Q V E +I F+F G G+QYVNMG ELY Sbjct: 1857 KEFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVNMGLELY 1916 Query: 549 HNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLVILFIFGYAL 608 E IFR+ +D+CFAILQ + + + +L+P+ +A E + R++ S ILF F YA+ Sbjct: 1917 EQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILFAFEYAV 1976 Query: 609 AELLMEWGIKPDVVIGYSLGEYIAGTVSGLFTLEQAIPLVLKRGRLFQQLPDGIMLSIPL 668 A+LLM WGIKP+ +IGYS GEY+A ++ +FTLE A+ LV+KRG+L LP G+MLS+PL Sbjct: 1977 AKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGVMLSVPL 2036 Query: 669 PPDKVLPLLGD-------SLEIAIDNQVSCVVGGPAHLVLELEEKLKQSKCVCTPLPTAK 721 P ++++ L+ ++ +A+ N +C+V G +++ E +LK+ + +C + Sbjct: 2037 PEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCMRVTIEG 2096 Query: 722 VIHTSRVESILDEYRAALQPVQYQPMKLRFMSSVTGDWAGPEELATSQYWIDQLQEKVSF 781 H+ ++SILDEY + + + + K+ ++S++TG W PEE YW+ ++ V F Sbjct: 2097 AAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHMRGTVRF 2156 Query: 782 VKAVQRLA-DTRTLFIEIGPGHDLSALVKRTFG-QGPNVQVLNLIPIGTSKVSEQHHLYD 839 +Q L D +LFIEIGPG+DLS L R + N ++ N + VS+ + L+ Sbjct: 2157 SDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSDMYFLFS 2216 Query: 840 RIGKLWQYGYSADWNTF--SPQGRRIPLPTYAFMRKKFWLEEPSFP--GRAGSQPYRMNR 895 I ++W G S DW F + RRIPLP Y+F + + L+ + + S+ ++++ Sbjct: 2217 HITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSKQSKISK 2276 Query: 896 -KNIEEWYYVPSWKRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKFTDKWKTVSEGSVTV 954 NI EW+Y P WK T P+ +E ++F D G + + VTV Sbjct: 2277 NNNISEWFYTPQWKSSTLF---EPNHDVNE-TWIVFVDQEGLGNELVKDLLNKGQRVVTV 2332 Query: 955 YKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWSLPFDQKEAHALVPD 1014 G K + D +INP DY L E+ +P +IH+W + ++++A + Sbjct: 2333 EPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNEERQASIEYVN 2392 Query: 1015 AGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSPHKATMLGPVKVIPL 1074 + G++S+ + +A G + +R+ITNGV +V+GD+ P K+T+LG V+P Sbjct: 2393 CKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQ 2452 Query: 1075 EYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNNSFWVPTCNAVTLD- 1133 EY + CS +D+ L + + +I+ LV + + + + AYR N +V T + L+ Sbjct: 2453 EYSYLSCSSVDVVLPLNKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQ 2512 Query: 1134 -TRHAMKIQPHGKYLITXXXXXXXXXXXXXXXRQARVELILAGRTPFPPKEEWAEWSAPH 1192 + + ++ +G YLIT + + L+L RT P ++EW H Sbjct: 2513 PAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEW----DMH 2568 Query: 1193 LAEE------IQKLTEIENSGGTVHVLQADISNPAEVQALLTQVEHTVGELTGVIHAAGV 1246 L E I+K+ EIE +G V+VL AD+++ +++ + + E G++ GVIH AG+ Sbjct: 2569 LKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKINGVIHGAGI 2628 Query: 1247 ADGE---LIQRSTRESSKNMLAAKVDGTLCLYEALRGKPLDFFILCSSLSSYLPAIGQAG 1303 G+ LIQ +E + +AK+ G + L E LR K LDF +L SS+S+ L +G Sbjct: 2629 LGGKTFNLIQELEKEDCEEQFSAKIYGLINLEECLRNKDLDFCVLMSSISAVLGGLGYVS 2688 Query: 1304 YCAANAFLDSFAFYAHAQNPGFPVLSVNWERWKQTGMSRRIEALHKELTGSELEDTITEG 1363 Y A+N ++D FA Y + + P +SVNW WK E ++ S E ++T Sbjct: 2689 YAASNIYMDVFAQYINRYSK-LPWISVNWSDWKY----WEDEEKDMQIGASVHELSMTPE 2743 Query: 1364 EGIQIFSRIGNLAVPQIII-SAFDMNERVQLYELAGSPLDFEGAE---SISHQQPVAGIF 1419 EG+Q F+ + +++I S ++ R+ + L S D + E ++ H Sbjct: 2744 EGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKEEELDSTLYHS------- 2796 Query: 1420 ERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDDSLFELGGDSLMALSILARVQKQW 1479 RP L TEYV PRNE E +L+++W F V VG+ D L ELGGDSL A++I++++ K++ Sbjct: 2797 -RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEF 2855 Query: 1480 NERIPMAYFINHPTVAGISSYMEQATPTESSGVKPVARREYYPLTSVQKRVYFLQKMHST 1539 N +P+ + +++Y+ +A +E + P + +Y L+S QKR Y L +++ Sbjct: 2856 NVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHYQLSSAQKRFYVLHRLYPE 2915 Query: 1540 TTVYNNPGIYQLESEIDTGXXXXXXXXXXXXHEILRTSFGFAGEEVVQRVHQNVVFSIEE 1599 +T YN+ + L +++ HEI RT+ ++ VQ +H + F I + Sbjct: 2916 STAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHITQ 2975 Query: 1600 LDGHEAGMDAVIAGFIRPFELEKAPLLRVGYLR---DKRILLIDMHHLVSDEMSYRLLIQ 1656 ++G E+ ++ +I FIRPF AP RVG +R K IL+ID+HH+V+D +SY + ++ Sbjct: 2976 IEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFVR 3035 Query: 1657 DFLALYEGKDLTVLPLQYKDYAAWQSGMKGSPAFVSQQQYWLDQFADGA 1705 D ALY G+ L L +QYKDY+ WQ K + +QYWLDQF DG Sbjct: 3036 DLFALYSGEKLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLDQFKDGV 3084 Score = 543 bits (1398), Expect = e-152, Method: Compositional matrix adjust. Identities = 279/639 (43%), Positives = 401/639 (62%), Gaps = 29/639 (4%) Query: 9 GLEIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAG 68 GLEIA+IG+A +FPGA+ QFW+NLK+G++S++ FT++EL +EGV + L + N+VKA Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 71 Query: 69 AVLDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGAS 128 L+ EYFDE FF Y+P++A +MDPQ+R+ E WE+LE AGY P Y GLIG++ GAS Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 129 SNYNWNARVYSYEGEHRDAFSEI-QLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXI 187 +N+NW + FSE LS KD +++ SYK LKGPS I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 188 HTACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGT 247 H ACRSLL+GEC +A AGG SI P ++GY Y EG S DG +R FD +A G +F +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 248 GAVVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGP 307 G V+LK LE+A+AD D I+ V+KGSA NNDG RK GY APSVEGQ EVI++A +EV P Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 308 DSISYIETHGTGTQLGDTIEFTALQQVFH--TRQSPCILGSVKNNIGHLDAASGVAGFMK 365 +ISYIETHGT T LGD+IE AL++ F ++S C +GSVK+N+GHLD A+GV G +K Sbjct: 312 STISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 366 AVLALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYP-LRAGVSSFGVGGMN 424 VL+++H+Q+PP +N + N ++ PF +NT L++W LRAGVS+FG GG N Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTN 431 Query: 425 AHLILEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTL 484 H++LE+AP V+ + +L++LSA+S E+L N T NL +++E + D+ + DVAYTL Sbjct: 432 VHIVLEEAP-KVKSSASTREKKLMVLSARSKEALNNATVNLVQYLESNKDVELADVAYTL 490 Query: 485 QAGRKPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMG 544 Q GR+PF +R+ ++C+D I+ L K + V + E PE +VF+ P + + + Sbjct: 491 QTGRRPFTYRRAVLCKDIDSAIDNL--KTVKDFHV-KTQENPE-LVFVLPSEYSSIIENV 546 Query: 545 RELYHNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLV---IL 601 +ELY EP+F + ++ Q+++ + F D SLV Sbjct: 547 KELYQKEPLFLQVFERNMTDAQMYTGKALKEAFFKG-------------TDDSLVEDLTF 593 Query: 602 FIFGYALAELLMEWGIKPDVVIGYSLGEYIAGTVSGLFT 640 F+ ++ ++L+E ++P +IG L AG VS ++ Sbjct: 594 FVCLQSIIDVLIECDVRPSNIIGTGL----AGMVSDIYN 628 Score = 279 bits (713), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 198/706 (28%), Positives = 342/706 (48%), Gaps = 64/706 (9%) Query: 826 IGTSKVSEQHHLYDRIGKLWQYGYSADWNT-FSPQGR-RIPLPTYAFMRKKFWLEEPSFP 883 I +++ Q+ L + +G+ W+ G +W+ + + R RI LPTY F +K++W++ Sbjct: 683 INNNQIILQNDLLELLGQAWELGVEINWSKLYEEEFRLRIALPTYPFEKKRYWIDPAEQQ 742 Query: 884 GRAGSQPYRMN-RKNIEEWYYVPSW--KRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKF 940 S+ + R NI EW+Y P W K + VT+ S + L+F D+ G Sbjct: 743 NIINSEETSIKKRSNIAEWFYTPGWMEKEIVDVTKG------STKSWLLFLDNEHIGLAL 796 Query: 941 TDKWKTVSEGSVTVYKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWS 1000 +K + +TV G K S +E I P EDY LF EL +P+E++HLW+ Sbjct: 797 KEKLERDGHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWN 856 Query: 1001 LPFDQKEAHALVPDAGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSP 1060 + D K+ + LD G++SL+++AK + +P+ + V+TN + +V+GD++ Sbjct: 857 V--DNKD----LGIETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIA 910 Query: 1061 HKATMLGPVKVIPLEYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNN 1120 K+T+L P+KV P EYP+IRC +D +L D + +I +L S++ A ++V A RNN Sbjct: 911 EKSTLLAPIKVFPQEYPNIRCRSVDF-MLSDNE--EALISNLYSEIQADIIDTVIAIRNN 967 Query: 1121 SFWVPTCNAVTLDTRHAM-------------KIQPHGKYLITXXXXXXXXXXXXXXXRQA 1167 + ++ + + M I+ G YLIT R Sbjct: 968 TRYIRIYEPIPDEKVSEMLVINENESASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTV 1027 Query: 1168 RVELILAGRTPFPPKEEW-----AEWSAPHLAEEIQKLTEIENSGGTVHVLQADISNPAE 1222 + +LIL RT P +EEW ++ L + I + ++E+ G V AD+++ + Sbjct: 1028 KAKLILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQ 1087 Query: 1223 VQALLTQVEHTVGELTGVIHAAGVADGELIQ----RSTRESSKNMLAAKVDGTLCLYEAL 1278 ++ ++ Q E G + GVIHAAGV + Q + +R + KV G L L + L Sbjct: 1088 MRNVIHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLL 1147 Query: 1279 RGKPLDFFILCSSLSSYLPAIGQAGYCAANAFLDSFA-FYAHAQNPGFPVLSVNWERWKQ 1337 LDF L SSLS L +G Y AAN +LDSF+ ++ N + S+NW W+ Sbjct: 1148 SNYDLDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT--SINWGDWQY 1205 Query: 1338 TGMSRRIEALHKELTGSELED-TITEGEGIQIFSRIGNLA-VPQIIISAFDMNERVQLYE 1395 TG E ++K +E +T EG + F + L+ + Q+IIS+ D+N+R + Sbjct: 1206 TGT----EQVNKIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQW- 1260 Query: 1396 LAGSPLDFEGAESISHQQPVAGIFERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMD 1455 ++ + IS E + T + ++E E + +W+ + V V ++ Sbjct: 1261 -----INLNSRKRISE-------LETQTKTGDKFRNQDEVEEVIIGIWKEFYSVDTVNVN 1308 Query: 1456 DSLFELGGDSLMALSILARVQKQWNERIPMAYFINHPTVAGISSYM 1501 ++ F+LG SL + I R+ + ++I + +P++ ++ Y+ Sbjct: 1309 ENFFDLGATSLHIIQIHERLINRLEKQISIGVMFEYPSIRSLAKYL 1354 >C0JRE5.1 C0JRE5_BACCE ZmaA Length = 3336 Score = 1233 bits (3189), Expect = 0.0, Method: Compositional matrix adjust. Identities = 670/1729 (38%), Positives = 1007/1729 (58%), Gaps = 56/1729 (3%) Query: 11 EIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAGAV 70 +IA+IG+ RFPGA N +FWNN+K G ES+ FTDEEL GV + + NYVKA Sbjct: 1376 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1435 Query: 71 LDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGASSN 130 L+ + FD FF Y+P+DA +MDPQ+R+FHE AW +LE AGY +TYPGLIGV++GAS N Sbjct: 1436 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1495 Query: 131 YNWNA-RVYSYEGEHRDAFSEIQLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXIHT 189 W S E F L++KD L+++ISYKFNLKGPSM IH Sbjct: 1496 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1555 Query: 190 ACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGTGA 249 AC++LL G CD+AIAGG ++ P ++GY YQEG S DGH R FDE A+G+LFG+G G Sbjct: 1556 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1615 Query: 250 VVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGPDS 309 VVLKPL+ A+ D D I AV+KG+A+NNDGNRK GY APSVEGQ EVI+ A + V P+S Sbjct: 1616 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1675 Query: 310 ISYIETHGTGTQLGDTIEFTALQQVFHTRQSPCI-LGSVKNNIGHLDAASGVAGFMKAVL 368 ISYIETHGT T+LGDTIE AL +VF++ + + +GSVK N+GHL+AASGVAG +K V Sbjct: 1676 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1735 Query: 369 ALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYPLRAGVSSFGVGGMNAHLI 428 A+K + +PP VNF K N + EK PF VN +L +W + PLRAGVSSFG+GG NAH+I Sbjct: 1736 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1795 Query: 429 LEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTLQAGR 488 LE+AP +E Q++++SA+S ++L+ MT NL H+E++P + + D +YTLQ GR Sbjct: 1796 LEEAP-KLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGR 1854 Query: 489 KPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMGRELY 548 K F+ R+ L+C ++ IE L + D R+ Q V E +I F+F G G+QYVNMG ELY Sbjct: 1855 KEFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVNMGLELY 1914 Query: 549 HNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLVILFIFGYAL 608 E IFR+ +D+CFAILQ + + + +L+P+ +A E + R++ S ILF F YA+ Sbjct: 1915 EQEAIFREAMDECFAILQSFTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILFAFEYAV 1974 Query: 609 AELLMEWGIKPDVVIGYSLGEYIAGTVSGLFTLEQAIPLVLKRGRLFQQLPDGIMLSIPL 668 A+LLM WGIKP+ +IGYS GEY+A ++ +FTLE A+ LV+KRG+L LP G+MLS+PL Sbjct: 1975 AKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGVMLSVPL 2034 Query: 669 PPDKVLPLLGD-------SLEIAIDNQVSCVVGGPAHLVLELEEKLKQSKCVCTPLPTAK 721 P ++++ L+ ++ +A+ N +C+V G +++ E +LK+ + +C + Sbjct: 2035 PEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCMRVTIEG 2094 Query: 722 VIHTSRVESILDEYRAALQPVQYQPMKLRFMSSVTGDWAGPEELATSQYWIDQLQEKVSF 781 H+ ++SILDEY + + + + K+ ++S++TG W PEE YW+ ++ V F Sbjct: 2095 AAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHMRGTVRF 2154 Query: 782 VKAVQRLA-DTRTLFIEIGPGHDLSALVKRTFG-QGPNVQVLNLIPIGTSKVSEQHHLYD 839 +Q L D +LFIEIGPG+DLS L R + N ++ N + VS+ + L+ Sbjct: 2155 SDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSDMYFLFS 2214 Query: 840 RIGKLWQYGYSADWNTF--SPQGRRIPLPTYAFMRKKFWLEEPSFP--GRAGSQPYRMNR 895 I ++W G S DW F + RRIPLP Y+F + + L+ + + S+ ++++ Sbjct: 2215 HITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSKQSKISK 2274 Query: 896 -KNIEEWYYVPSWKRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKFTDKWKTVSEGSVTV 954 NI EW+Y P WK T P+ +E ++F D G + + VTV Sbjct: 2275 NNNISEWFYTPQWKSSTLF---EPNHDVNE-TWIVFVDQEGLGNELVKDLLNKGQRVVTV 2330 Query: 955 YKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWSLPFDQKEAHALVPD 1014 G K + D +INP DY L E+ +P +IH+W + ++++A + Sbjct: 2331 EPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNEERQASIEYVN 2390 Query: 1015 AGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSPHKATMLGPVKVIPL 1074 + G++S+ + +A G + +R+ITNGV +V+GD+ P K+T+LG V+P Sbjct: 2391 CKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQ 2450 Query: 1075 EYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNNSFWVPTCNAVTLD- 1133 EY + CS +D+ L + +I+ LV + + + + AYR N +V T + L+ Sbjct: 2451 EYSYLSCSSVDVVLPLKKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQ 2510 Query: 1134 -TRHAMKIQPHGKYLITXXXXXXXXXXXXXXXRQARVELILAGRTPFPPKEEWAEWSAPH 1192 + + ++ +G YLIT + + L+L RT P ++EW H Sbjct: 2511 PAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEW----DMH 2566 Query: 1193 LAEE------IQKLTEIENSGGTVHVLQADISNPAEVQALLTQVEHTVGELTGVIHAAGV 1246 L E I+K+ EIE +G V+VL AD+++ +++ + + E G++ GVIH AG+ Sbjct: 2567 LKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKINGVIHGAGI 2626 Query: 1247 ADGE---LIQRSTRESSKNMLAAKVDGTLCLYEALRGKPLDFFILCSSLSSYLPAIGQAG 1303 G+ LIQ +E + +AK+ G L L E LR K LDF +L SS+S+ L +G Sbjct: 2627 LGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVLGGLGYVS 2686 Query: 1304 YCAANAFLDSFAFYAHAQNPGFPVLSVNWERWKQTGMSRRIEALHKELTGSELEDTITEG 1363 Y A+N ++D FA Y + + P +SVNW WK E ++ S E ++T Sbjct: 2687 YAASNIYMDVFAQYINRYSK-LPWISVNWSDWKY----WEDEEKDMQIGASVHELSMTPE 2741 Query: 1364 EGIQIFSRIGNLAVPQIII-SAFDMNERVQLYELAGSPLDFEGAE---SISHQQPVAGIF 1419 EG+Q F+ + +++I S ++ R+ + L S D + E ++ H Sbjct: 2742 EGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKEEELDSTLYHS------- 2794 Query: 1420 ERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDDSLFELGGDSLMALSILARVQKQW 1479 RP L TEYV PRNE E +L+++W F V VG+ D L ELGGDSL A++I++++ K++ Sbjct: 2795 -RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEF 2853 Query: 1480 NERIPMAYFINHPTVAGISSYMEQATPTESSGVKPVARREYYPLTSVQKRVYFLQKMHST 1539 N +P+ + +++Y+ +A +E + P + +Y L+S QKR Y L +++ Sbjct: 2854 NVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHYQLSSAQKRFYVLHRLYPE 2913 Query: 1540 TTVYNNPGIYQLESEIDTGXXXXXXXXXXXXHEILRTSFGFAGEEVVQRVHQNVVFSIEE 1599 +T YN+ + L +++ HEI RT+ ++ VQ +H + F I + Sbjct: 2914 STAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHITQ 2973 Query: 1600 LDGHEAGMDAVIAGFIRPFELEKAPLLRVGYLR---DKRILLIDMHHLVSDEMSYRLLIQ 1656 ++G E+ ++ +I FIRPF AP RVG +R K IL+ID+HH+V+D +SY + ++ Sbjct: 2974 IEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFVR 3033 Query: 1657 DFLALYEGKDLTVLPLQYKDYAAWQSGMKGSPAFVSQQQYWLDQFADGA 1705 D ALY G+ L L +QYKDY+ WQ K + +QYWL+QF DG Sbjct: 3034 DLFALYSGEKLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLEQFKDGV 3082 Score = 540 bits (1391), Expect = e-151, Method: Compositional matrix adjust. Identities = 277/639 (43%), Positives = 400/639 (62%), Gaps = 29/639 (4%) Query: 9 GLEIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAG 68 GLEIA+IG+A +FPGA+ QFW+NLK+G++S++ FT++EL +EGV + L + N+VKA Sbjct: 10 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 69 Query: 69 AVLDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGAS 128 L+ EYFDE FF Y+P++A +MDPQ+R+ E WE+LE AGY P Y GLIG++ GAS Sbjct: 70 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 129 Query: 129 SNYNWNARVYSYEGEHRDAFSEI-QLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXI 187 +N+NW + FSE LS KD +++ SYK LKGPS I Sbjct: 130 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 189 Query: 188 HTACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGT 247 H ACRSLL+GEC +A AGG SI P ++GY Y EG S DG +R FD +A G +F +G Sbjct: 190 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 249 Query: 248 GAVVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGP 307 G V+LK LE+A+AD D I+ V+KGSA NNDG RK GY APSVEGQ EVI++A +EV P Sbjct: 250 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 309 Query: 308 DSISYIETHGTGTQLGDTIEFTALQQVFH--TRQSPCILGSVKNNIGHLDAASGVAGFMK 365 +ISY+ETHGT T LGD+IE AL++ F ++S C +GSVK+N+GHLD A+GV G +K Sbjct: 310 STISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 369 Query: 366 AVLALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYP-LRAGVSSFGVGGMN 424 VL+++H+Q+PP +N + N ++ PF +NT L++W LRAGVS+FG GG N Sbjct: 370 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSDDNDLLRAGVSAFGYGGTN 429 Query: 425 AHLILEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTL 484 H++LE+AP V+ + +L++LSA+S E+L N T N+ +++E + D+ + DVAYTL Sbjct: 430 VHIVLEEAP-KVKSSASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELADVAYTL 488 Query: 485 QAGRKPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMG 544 Q GR+PF +R+ ++C D I+ L K + V + E P+ +VF+ P + + + Sbjct: 489 QTGRRPFPYRRAVLCMDIDSAIDNL--KTVKDFHV-KTQENPD-LVFVLPSEYSSIIENV 544 Query: 545 RELYHNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLV---IL 601 +ELY EP+F K ++ Q+++ + F D SLV Sbjct: 545 KELYQKEPLFLKVFERNMTDAQMYTGKALKEAFFKG-------------TDDSLVEDLTF 591 Query: 602 FIFGYALAELLMEWGIKPDVVIGYSLGEYIAGTVSGLFT 640 F+ ++ ++L+E ++P +IG L AG VS ++ Sbjct: 592 FVCLQSIIDVLIECDVRPSNIIGTGL----AGMVSDIYN 626 Score = 276 bits (706), Expect = 1e-71, Method: Compositional matrix adjust. Identities = 195/705 (27%), Positives = 341/705 (48%), Gaps = 62/705 (8%) Query: 826 IGTSKVSEQHHLYDRIGKLWQYGYSADWNTFSPQGRR--IPLPTYAFMRKKFWLEEPSFP 883 I +++ Q+ L + +G+ W+ G +W+ + R I LPTY F +K++W++ Sbjct: 681 INNNQIILQNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQQ 740 Query: 884 GRAGSQPYRMN-RKNIEEWYYVPSW--KRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKF 940 ++ + R NI EW+Y P W K + VT+ +S + L+F D+ G Sbjct: 741 NITNNEETSIKKRSNIAEWFYTPGWMEKEIVDVTK------ESTKSWLLFLDNEHIGLAL 794 Query: 941 TDKWKTVSEGSVTVYKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWS 1000 +K + +TV G K S +E I P EDY LF EL +P+E++HLW+ Sbjct: 795 KEKLERDGHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWN 854 Query: 1001 LPFDQKEAHALVPDAGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSP 1060 + D K+ + LD G++SL+++AK + +P+ + V+TN + +V+GD++ Sbjct: 855 V--DNKD----LGIKTLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIA 908 Query: 1061 HKATMLGPVKVIPLEYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNN 1120 K+T+L P+KV P EYP+IRC +D +L D + +I +L S++ ++V A RNN Sbjct: 909 EKSTLLAPIKVFPQEYPNIRCRSVDF-MLSDNE--EALISNLYSEIQTDIIDTVIAIRNN 965 Query: 1121 SFWVPTCNAVTLDTRHAM-------------KIQPHGKYLITXXXXXXXXXXXXXXXRQA 1167 + ++ + + M I+ G YLIT R Sbjct: 966 TRYIRIYEPIPDEKVSEMLVINENELASKIPNIRSKGVYLITGGMGGVGLKLAEYLARTV 1025 Query: 1168 RVELILAGRTPFPPKEEWAE-----WSAPHLAEEIQKLTEIENSGGTVHVLQADISNPAE 1222 + +LIL RT P +EEW E L + I + ++E+ G V AD+++ + Sbjct: 1026 KAKLILVSRTALPDREEWDEILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQ 1085 Query: 1223 VQALLTQVEHTVGELTGVIHAAGVADGELIQ----RSTRESSKNMLAAKVDGTLCLYEAL 1278 ++ ++ Q E G + GVIHAAGV + Q + +R + KV G L L + L Sbjct: 1086 MRNVIHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLL 1145 Query: 1279 RGKPLDFFILCSSLSSYLPAIGQAGYCAANAFLDSFA-FYAHAQNPGFPVLSVNWERWKQ 1337 LDF L SSLS L +G Y AAN +LDSF+ ++ N + S+NW W+ Sbjct: 1146 SNYDLDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT--SINWGDWQY 1203 Query: 1338 TGMSRRIEALHKELTGSELEDTITEGEGIQIFSRIGNLA-VPQIIISAFDMNERVQLYEL 1396 TG ++++ + + LE +T EG + F + L+ + Q+IIS+ D+N+R + Sbjct: 1204 TG-AQQVNKIFNAQSIEALE--MTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQW-- 1258 Query: 1397 AGSPLDFEGAESISHQQPVAGIFERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDD 1456 ++ + IS E + T + ++E E + +W+ + V V +++ Sbjct: 1259 ----INLNSRKRISE-------LETQTKTGDKFRNQDEVEEIIIGIWKEFYSVDTVNVNE 1307 Query: 1457 SLFELGGDSLMALSILARVQKQWNERIPMAYFINHPTVAGISSYM 1501 + F+LG SL + I R+ + ++I + +P++ ++ Y+ Sbjct: 1308 NFFDLGATSLHIIQIHERLINRLEKQISIGVMFEYPSIRSLARYL 1352 >C2XEJ3.1 C2XEJ3_BACCE Polyketide synthase type I Length = 3339 Score = 1232 bits (3187), Expect = 0.0, Method: Compositional matrix adjust. Identities = 669/1729 (38%), Positives = 1009/1729 (58%), Gaps = 56/1729 (3%) Query: 11 EIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAGAV 70 +IA+IG+ RFPGA N +FWNN+K G ES+ FTDEEL GV + + NYVKA Sbjct: 1379 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1438 Query: 71 LDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGASSN 130 L+ + FD FF Y+P+DA +MDPQ+R+FHE AW +LE AGY +TYPGLIGV++GAS N Sbjct: 1439 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1498 Query: 131 YNWNA-RVYSYEGEHRDAFSEIQLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXIHT 189 W S E F L++KD L+++ISYKFNLKGPSM IH Sbjct: 1499 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1558 Query: 190 ACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGTGA 249 AC++LL G CD+AIAGG ++ P ++GY YQEG S DGH R FDE A+G+LFG+G G Sbjct: 1559 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1618 Query: 250 VVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGPDS 309 VVLKPL+ A+ D D I AV+KG+A+NNDGNRK GY APSVEGQ EVI+ A + V P+S Sbjct: 1619 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1678 Query: 310 ISYIETHGTGTQLGDTIEFTALQQVFHTRQSPCI-LGSVKNNIGHLDAASGVAGFMKAVL 368 ISYIETHGT T+LGDTIE AL +VF++ + + +GSVK N+GHL+AASGVAG +K V Sbjct: 1679 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1738 Query: 369 ALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYPLRAGVSSFGVGGMNAHLI 428 A+K + +PP VNF K N + EK PF VN +L +W + PLRAGVSSFG+GG NAH+I Sbjct: 1739 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGGTNAHII 1798 Query: 429 LEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTLQAGR 488 LE+AP +E Q++++SA+S ++L+ MT NL H+E++P + + D +YTLQ GR Sbjct: 1799 LEEAP-KLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSYTLQIGR 1857 Query: 489 KPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMGRELY 548 K F+ R+ L+C ++ IE L + + R+ Q V E ++ F+F G G+QYVNMG ELY Sbjct: 1858 KEFKHRRALVCSSTQEGIELLNQPEGRRVQYVNVKEEHPKVNFLFSGNGSQYVNMGLELY 1917 Query: 549 HNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLVILFIFGYAL 608 E IFR+ +D+CFAILQ + + + +L+P+ ++A E + R++ S ILF F YA+ Sbjct: 1918 EQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILFAFEYAV 1977 Query: 609 AELLMEWGIKPDVVIGYSLGEYIAGTVSGLFTLEQAIPLVLKRGRLFQQLPDGIMLSIPL 668 A+LLM WGIKP+ +IGYS GEY+A ++ +FTLE A+ LV+KRG+L LP G+MLS+PL Sbjct: 1978 AKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGVMLSVPL 2037 Query: 669 PPDKVLPLLGD-------SLEIAIDNQVSCVVGGPAHLVLELEEKLKQSKCVCTPLPTAK 721 P ++++ L+ ++ +A+ N +C+V G +++ E +LK+ + +C + Sbjct: 2038 PEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKKRLMCMRVTIEG 2097 Query: 722 VIHTSRVESILDEYRAALQPVQYQPMKLRFMSSVTGDWAGPEELATSQYWIDQLQEKVSF 781 H+ ++SILDEY + + + + K+ ++S++TG W PEE YW+ ++ V F Sbjct: 2098 AAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHMRGTVRF 2157 Query: 782 VKAVQRLA-DTRTLFIEIGPGHDLSALVKRTFG-QGPNVQVLNLIPIGTSKVSEQHHLYD 839 +Q L D +LFIEIGPG+DLS L R + N ++ N + VS+ + L+ Sbjct: 2158 SDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSDMYFLFS 2217 Query: 840 RIGKLWQYGYSADWNTF--SPQGRRIPLPTYAFMRKKFWLEEPSFP--GRAGSQPYRMNR 895 I ++W G S DW F + RRIPLP Y+F + + L+ + + S+ ++++ Sbjct: 2218 HITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSKQSKISK 2277 Query: 896 -KNIEEWYYVPSWKRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKFTDKWKTVSEGSVTV 954 NI EW+Y P WK T P+ +E ++F D G + + VTV Sbjct: 2278 NNNISEWFYTPQWKSSTLF---EPNHDVNE-TWIVFVDQEGLGNELVKDLLNKGQRVVTV 2333 Query: 955 YKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWSLPFDQKEAHALVPD 1014 G K + D +INP DY L E+ +P +IH+W + ++++A + Sbjct: 2334 EPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNEERQASIEYVN 2393 Query: 1015 AGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSPHKATMLGPVKVIPL 1074 + G++S+ + +A G + +R+ITNGV +V+GD+ P K+T+LG V+P Sbjct: 2394 CKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQ 2453 Query: 1075 EYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNNSFWVPTCNAVTLD- 1133 EY + CS +D+ L + + +I+ LV + + + + AYR N +V T + L+ Sbjct: 2454 EYSYLSCSSVDVVLPLNKEWKNRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQ 2513 Query: 1134 -TRHAMKIQPHGKYLITXXXXXXXXXXXXXXXRQARVELILAGRTPFPPKEEWAEWSAPH 1192 + + ++ +G YLIT + + L+L RT P ++EW H Sbjct: 2514 PAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTLQANLVLLTRTGLPNRDEW----DMH 2569 Query: 1193 LAEE------IQKLTEIENSGGTVHVLQADISNPAEVQALLTQVEHTVGELTGVIHAAGV 1246 L E I+K+ EIE +G V+VL AD+++ +++ + + E G++ GVIH AG+ Sbjct: 2570 LKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKINGVIHGAGI 2629 Query: 1247 ADGE---LIQRSTRESSKNMLAAKVDGTLCLYEALRGKPLDFFILCSSLSSYLPAIGQAG 1303 G+ LIQ +E + +AK+ G L L E LR K LDF +L SS+S+ L +G Sbjct: 2630 LGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVLGGLGYVS 2689 Query: 1304 YCAANAFLDSFAFYAHAQNPGFPVLSVNWERWKQTGMSRRIEALHKELTGSELEDTITEG 1363 Y A+N ++D FA Y + + P +SVNW WK E ++ S E ++T Sbjct: 2690 YAASNIYMDVFAQYINRYSK-LPWISVNWSDWKY----WEDEEKDMQIGASVHELSMTPE 2744 Query: 1364 EGIQIFSRIGNLAVPQIII-SAFDMNERVQLYELAGSPLDFEGAE---SISHQQPVAGIF 1419 EG+Q F+ + +++I S ++ R+ + L S D + E ++ H Sbjct: 2745 EGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKEEELDSTLYHS------- 2797 Query: 1420 ERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDDSLFELGGDSLMALSILARVQKQW 1479 RP L TEYV PRNE E +L+++W F V VG+ D L ELGGDSL A++I++++ K++ Sbjct: 2798 -RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEF 2856 Query: 1480 NERIPMAYFINHPTVAGISSYMEQATPTESSGVKPVARREYYPLTSVQKRVYFLQKMHST 1539 N +P+ + +++Y+ +A +E + P + +Y L+S QKR Y L +++ Sbjct: 2857 NVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHYQLSSAQKRFYVLHRLYPE 2916 Query: 1540 TTVYNNPGIYQLESEIDTGXXXXXXXXXXXXHEILRTSFGFAGEEVVQRVHQNVVFSIEE 1599 +T YN+ + L +++ HEI RT+ ++ VQ +H + F I + Sbjct: 2917 STAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHITQ 2976 Query: 1600 LDGHEAGMDAVIAGFIRPFELEKAPLLRVGYLR---DKRILLIDMHHLVSDEMSYRLLIQ 1656 ++G E+ ++ +I FIRPF AP RVG +R K IL+ID+HH+V+D +SY + ++ Sbjct: 2977 IEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFVR 3036 Query: 1657 DFLALYEGKDLTVLPLQYKDYAAWQSGMKGSPAFVSQQQYWLDQFADGA 1705 D ALY G+ L L +QYKDY+ WQ K + +QYWLDQF DG Sbjct: 3037 DLFALYSGEKLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLDQFKDGV 3085 Score = 538 bits (1386), Expect = e-150, Method: Compositional matrix adjust. Identities = 277/639 (43%), Positives = 399/639 (62%), Gaps = 29/639 (4%) Query: 9 GLEIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAG 68 GLEIA+IG+A +FPGA+ QFW+NLK+G++S++ FT++EL +EGV E L + N+VKA Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLEVLQHPNFVKAK 71 Query: 69 AVLDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGAS 128 L+ EYFDE FF Y+P++A +MDPQ+R+ E WE+LE AGY P Y GLIG++ GAS Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 129 SNYNWNARVYSYEGEHRDAFSEI-QLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXI 187 +N+NW + FSE LS KD +++ SYK LKGPS I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 188 HTACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGT 247 H ACRSLL+GEC +A AGG SI P ++GY Y EG S DG +R FD +A G +F +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 248 GAVVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGP 307 G V+LK LE+A+AD D I+ V+KGSA NNDG RK GY APSVEGQ EVI++A +EV P Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 308 DSISYIETHGTGTQLGDTIEFTALQQVFH--TRQSPCILGSVKNNIGHLDAASGVAGFMK 365 +ISYIETHGT T LGD+IE AL++ F ++S C +GSVK+N+GHLD A+GV G +K Sbjct: 312 STISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 366 AVLALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYP-LRAGVSSFGVGGMN 424 VL+++H+Q+PP +N + N ++ PF +NT L++W LRAGVS+FG GG N Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTN 431 Query: 425 AHLILEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTL 484 H++LE+AP V+ + +L++LSA+S E+L N T N+ ++E + D+ + DVAYTL Sbjct: 432 VHIVLEEAP-KVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTL 490 Query: 485 QAGRKPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMG 544 Q GR+ F +R+ ++C+D I+ L K + V + E P+ +VF+ P + + + Sbjct: 491 QTGRRSFPYRRAVLCKDIDSAIDNL--KTVKDFHV-KTQENPD-LVFVLPSEYSSIIENV 546 Query: 545 RELYHNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLV---IL 601 +ELY EP+F + ++ Q+++ + F D SLV Sbjct: 547 KELYQKEPLFLQVFERNMTDAQMYTGKALKEAFFKG-------------TDDSLVEDLTF 593 Query: 602 FIFGYALAELLMEWGIKPDVVIGYSLGEYIAGTVSGLFT 640 F+ ++ ++L+E ++P +IG L AG VS ++ Sbjct: 594 FVCLQSIIDVLIECDVRPSNIIGTGL----AGMVSDIYN 628 Score = 273 bits (699), Expect = 9e-71, Method: Compositional matrix adjust. Identities = 195/707 (27%), Positives = 338/707 (47%), Gaps = 65/707 (9%) Query: 826 IGTSKVSEQHHLYDRIGKLWQYGYSADWNTFSPQGRR--IPLPTYAFMRKKFWLE--EPS 881 I +++ Q+ L + +G+ W+ G +W+ + R I LPTY F +K++W++ E Sbjct: 683 INNNQIILQNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQQ 742 Query: 882 FPGRAGSQPYRMNRKNIEEWYYVPSW--KRLTPVTQAAPSQAKSERRRLIFGDHSSAGQK 939 + + R NI +W+Y P W K + VT+ S + L+F D+ G Sbjct: 743 NITNSEEETSIKKRSNIAKWFYTPGWMEKEIVDVTKG------STKSWLLFLDNEHIGLA 796 Query: 940 FTDKWKTVSEGSVTVYKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLW 999 +K + +TV G K S +E I P EDY LF EL +P+E++HLW Sbjct: 797 LKEKLERDGHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLW 856 Query: 1000 SLPFDQKEAHALVPDAGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATS 1059 ++ D K+ + LD G++SL+++AK + +P+ + V+TN + +V+GD++ Sbjct: 857 NV--DNKD----LGIETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESII 910 Query: 1060 PHKATMLGPVKVIPLEYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRN 1119 K+T+L P+KV P EYP+IRC +D +L D + +I +L S++ ++V A RN Sbjct: 911 AEKSTLLAPIKVFPQEYPNIRCRSVDF-MLSDNE--EALISNLYSEIQTDIIDTVIAIRN 967 Query: 1120 NSFWVPTCNAVTLDTRHAM-------------KIQPHGKYLITXXXXXXXXXXXXXXXRQ 1166 N+ ++ + + M I+ G YLIT R Sbjct: 968 NTRYIRIYEPIPDEKVSEMLVINENESASKIPNIRSEGVYLITGGIGGVGLKLAEYLART 1027 Query: 1167 ARVELILAGRTPFPPKEEW-----AEWSAPHLAEEIQKLTEIENSGGTVHVLQADISNPA 1221 + +LIL RT P +EEW ++ L + I + ++E+ G V AD+++ Sbjct: 1028 VKAKLILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEE 1087 Query: 1222 EVQALLTQVEHTVGELTGVIHAAGVADGELIQ----RSTRESSKNMLAAKVDGTLCLYEA 1277 +++ ++ Q E G + GVIHAAGV + Q + +R + KV G L L + Sbjct: 1088 QMRNVIHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKL 1147 Query: 1278 LRGKPLDFFILCSSLSSYLPAIGQAGYCAANAFLDSFA-FYAHAQNPGFPVLSVNWERWK 1336 L LDF L SSLS L +G Y AAN +LDSF+ ++ N + +S+NW W+ Sbjct: 1148 LSNYDLDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRW--ISINWGDWQ 1205 Query: 1337 QTGMSRRIEALHKELTGSELED-TITEGEGIQIFSRIGNLA-VPQIIISAFDMNERVQLY 1394 TG E ++K +E +T EG + F + L+ + Q+IIS+ D+N+R + Sbjct: 1206 YTGT----EQVNKIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQW 1261 Query: 1395 ELAGSPLDFEGAESISHQQPVAGIFERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGM 1454 ++ + IS E + T + ++E E + +W+ + V V Sbjct: 1262 ------INLNSRKRISE-------LETQTKTGDKFRNQDEVEEIIIGIWKEFYSVDTVNE 1308 Query: 1455 DDSLFELGGDSLMALSILARVQKQWNERIPMAYFINHPTVAGISSYM 1501 +++ F+LG SL + I R+ + + I + +P++ ++ Y+ Sbjct: 1309 NENFFDLGATSLHIIQIHERLINRLEKHISIGVMFEYPSIRSLAKYL 1355 >C2N7K8.1 C2N7K8_BACCE Polyketide synthase type I Length = 3338 Score = 1231 bits (3185), Expect = 0.0, Method: Compositional matrix adjust. Identities = 668/1729 (38%), Positives = 1007/1729 (58%), Gaps = 56/1729 (3%) Query: 11 EIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAGAV 70 +IA+IG+ RFPGA N +FWNN+K G ES+ FTDEEL GV + + NYVKA Sbjct: 1378 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1437 Query: 71 LDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGASSN 130 L+ + FD FF Y+P+DA +MDPQ+R+FHE AW +LE AGY +TYPGLIGV++GAS N Sbjct: 1438 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1497 Query: 131 YNWNA-RVYSYEGEHRDAFSEIQLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXIHT 189 W S E F L++KD L+++ISYKFNLKGPSM IH Sbjct: 1498 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1557 Query: 190 ACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGTGA 249 AC++LL G CD+AIAGG ++ P ++GY YQEG S DGH R FDE A+G+LFG+G G Sbjct: 1558 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1617 Query: 250 VVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGPDS 309 VVLKPL+ A+ D D I AV+KG+A+NNDGNRK GY APSVEGQ EVI+ A + V P+S Sbjct: 1618 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1677 Query: 310 ISYIETHGTGTQLGDTIEFTALQQVFHTRQSPCI-LGSVKNNIGHLDAASGVAGFMKAVL 368 ISYIETHGT T+LGDTIE AL +VF++ + + +GSVK N+GHL+AASGVAG +K V Sbjct: 1678 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1737 Query: 369 ALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYPLRAGVSSFGVGGMNAHLI 428 A+K + +PP VNF K N + EK PF VN +L +W + PLRAGVSSFG+GG NAH+I Sbjct: 1738 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQQLNEWKEDNKPLRAGVSSFGIGGTNAHII 1797 Query: 429 LEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTLQAGR 488 LE+AP +E Q++++SA+S ++L+ MT NL H+E++P + + D +YTLQ GR Sbjct: 1798 LEEAP-KLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADASYTLQIGR 1856 Query: 489 KPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMGRELY 548 K F+ R+ L+C ++ IE L + D R+ Q V E +I F+F G G+QYVNMG ELY Sbjct: 1857 KEFKHRRALVCSSTQEGIEQLNQPDGRRVQYANVKEEHPKIHFLFSGNGSQYVNMGLELY 1916 Query: 549 HNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLVILFIFGYAL 608 E IFR+ +D+CFAILQ + + + +L+P+ +A E + R++ S ILF F YA+ Sbjct: 1917 EQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSINEATEKLKRMEFSQPILFAFEYAV 1976 Query: 609 AELLMEWGIKPDVVIGYSLGEYIAGTVSGLFTLEQAIPLVLKRGRLFQQLPDGIMLSIPL 668 A+LLM WGIKP+ +IGYS GEY+A ++ +FTLE A+ LV+KRG+L LP G+MLS+PL Sbjct: 1977 AKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGVMLSVPL 2036 Query: 669 PPDKVLPLLGD-------SLEIAIDNQVSCVVGGPAHLVLELEEKLKQSKCVCTPLPTAK 721 P ++++ L+ ++ +A+ N +C+V G +++ E +LK+ + +C + Sbjct: 2037 PEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCMRVTIEG 2096 Query: 722 VIHTSRVESILDEYRAALQPVQYQPMKLRFMSSVTGDWAGPEELATSQYWIDQLQEKVSF 781 H+ ++SILDEY + + + + K+ ++S++TG W PEE YW+ ++ V F Sbjct: 2097 AAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHMRGTVRF 2156 Query: 782 VKAVQRLA-DTRTLFIEIGPGHDLSALVKRTFG-QGPNVQVLNLIPIGTSKVSEQHHLYD 839 +Q L D +LFIEIGPG+DLS L R + N ++ N + VS+ + L+ Sbjct: 2157 SDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSDMYFLFS 2216 Query: 840 RIGKLWQYGYSADWNTF--SPQGRRIPLPTYAFMRKKFWLEEPSFP--GRAGSQPYRMNR 895 I ++W G S DW F + RRIPLP Y+F + + L+ + + S+ ++++ Sbjct: 2217 HITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSKQSKISK 2276 Query: 896 -KNIEEWYYVPSWKRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKFTDKWKTVSEGSVTV 954 NI EW+Y P WK T P+ +E ++F D G + + VTV Sbjct: 2277 NNNISEWFYTPQWKSSTLF---EPNHDVNE-TWIVFVDQEGLGNELVKDLLNKGQRVVTV 2332 Query: 955 YKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWSLPFDQKEAHALVPD 1014 G K + D +INP DY L E+ +P +IH+W + ++++A + Sbjct: 2333 EPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNEERQASIEYVN 2392 Query: 1015 AGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSPHKATMLGPVKVIPL 1074 + G++S+ + +A G + +R+ITNGV +V+GD+ P K+T+LG V+P Sbjct: 2393 CKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQ 2452 Query: 1075 EYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNNSFWVPTCNAVTLD- 1133 EY + CS +D+ L + +I+ L+ + + + + AYR N +V T + L+ Sbjct: 2453 EYSYLSCSSVDVVLPLNKEGKSRLINQLIEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQ 2512 Query: 1134 -TRHAMKIQPHGKYLITXXXXXXXXXXXXXXXRQARVELILAGRTPFPPKEEWAEWSAPH 1192 + + ++ +G YLIT + + ++L RT P ++EW H Sbjct: 2513 PAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANIVLLTRTGLPNRDEW----DMH 2568 Query: 1193 LAEE------IQKLTEIENSGGTVHVLQADISNPAEVQALLTQVEHTVGELTGVIHAAGV 1246 L E I+K+ EIE +G V+VL AD+++ +++ + + E G++ GVIH AG+ Sbjct: 2569 LKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKINGVIHGAGI 2628 Query: 1247 ADGE---LIQRSTRESSKNMLAAKVDGTLCLYEALRGKPLDFFILCSSLSSYLPAIGQAG 1303 G+ LIQ +E + +AK+ G L L E LR K LDF +L SS+S+ L +G Sbjct: 2629 LGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVLGGLGYVS 2688 Query: 1304 YCAANAFLDSFAFYAHAQNPGFPVLSVNWERWKQTGMSRRIEALHKELTGSELEDTITEG 1363 Y A+N ++D FA Y + + P +SVNW WK E ++ S E ++T Sbjct: 2689 YAASNIYMDVFAQYIN-RYSNLPWISVNWSDWKY----WEDEEKDMQIGASVHELSMTPE 2743 Query: 1364 EGIQIFSRIGNLAVPQIII-SAFDMNERVQLYELAGSPLDFEGAE---SISHQQPVAGIF 1419 EG+Q F+ + +++I S ++ R+ + L S D + E ++ H Sbjct: 2744 EGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKEEELDSTLYHS------- 2796 Query: 1420 ERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDDSLFELGGDSLMALSILARVQKQW 1479 RP L TEYV PRNE E +L+++W F V VG+ D L ELGGDSL A++I++++ K++ Sbjct: 2797 -RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEF 2855 Query: 1480 NERIPMAYFINHPTVAGISSYMEQATPTESSGVKPVARREYYPLTSVQKRVYFLQKMHST 1539 N +P+ + +++Y+ +A +E + P + +Y L+S QKR Y L +++ Sbjct: 2856 NVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSHYQLSSAQKRFYVLHRLYPE 2915 Query: 1540 TTVYNNPGIYQLESEIDTGXXXXXXXXXXXXHEILRTSFGFAGEEVVQRVHQNVVFSIEE 1599 +T YN+ + L +++ HEI RT+ ++ VQ +H + F I + Sbjct: 2916 STAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHITQ 2975 Query: 1600 LDGHEAGMDAVIAGFIRPFELEKAPLLRVGYLR---DKRILLIDMHHLVSDEMSYRLLIQ 1656 ++G E+ ++ +I FIRPF AP RVG +R K IL+ID+HH+V+D +SY + ++ Sbjct: 2976 IEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFVR 3035 Query: 1657 DFLALYEGKDLTVLPLQYKDYAAWQSGMKGSPAFVSQQQYWLDQFADGA 1705 D ALY G+ L L +QYKDY+ WQ K + +QYWL+QF DG Sbjct: 3036 DLFALYSGEKLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLEQFKDGV 3084 Score = 538 bits (1386), Expect = e-150, Method: Compositional matrix adjust. Identities = 277/639 (43%), Positives = 399/639 (62%), Gaps = 29/639 (4%) Query: 9 GLEIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAG 68 GLEIA+IG+A +FPGA+ QFW+NLK+G++S++ FT++EL +EGV + L + N+VKA Sbjct: 12 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 71 Query: 69 AVLDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGAS 128 L+ EYFDE FF Y+P++A +MDPQ+R+ E WE+LE AGY P Y GLIG++ GAS Sbjct: 72 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 131 Query: 129 SNYNWNARVYSYEGEHRDAFSEI-QLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXI 187 +N+NW + FSE LS KD +++ SYK LKGPS I Sbjct: 132 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 191 Query: 188 HTACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGT 247 H ACRSLL+GEC +A AGG SI P ++GY Y EG S DG +R FD +A G +F +G Sbjct: 192 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 251 Query: 248 GAVVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGP 307 G V+LK LE+A+AD D I+ V+KGSA NNDG RK GY APSVEGQ EVI++A +EV P Sbjct: 252 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 311 Query: 308 DSISYIETHGTGTQLGDTIEFTALQQVFH--TRQSPCILGSVKNNIGHLDAASGVAGFMK 365 +ISYIETHGT T LGD+IE AL++ F ++S C +GSVK+N+GHLD A+GV G +K Sbjct: 312 STISYIETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 371 Query: 366 AVLALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYP-LRAGVSSFGVGGMN 424 VL+++H+Q+PP +N + N ++ PF +NT L++W LRAGVS+FG GG N Sbjct: 372 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDNDLLRAGVSAFGYGGTN 431 Query: 425 AHLILEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTL 484 H++LE+AP V+ + +L++LSA+S E+L N T N+ ++E + D+ + DVAYTL Sbjct: 432 VHIVLEEAP-KVKSSASTREKKLMVLSARSKEALNNATVNMVEYLESNKDVELADVAYTL 490 Query: 485 QAGRKPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMG 544 Q GR+ F +R+ ++C+D I+ L K + V + E P+ +VF+ P + + + Sbjct: 491 QTGRRSFPYRRAVLCKDIDSAIDNL--KTVKDFHV-KTQENPD-LVFVLPSEYSSIIENV 546 Query: 545 RELYHNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLV---IL 601 +ELY EP+F K ++ Q+++ + F D SLV Sbjct: 547 KELYQKEPLFLKVFERNMTDAQMYTGKALKEAFFKG-------------TDDSLVEDLTF 593 Query: 602 FIFGYALAELLMEWGIKPDVVIGYSLGEYIAGTVSGLFT 640 F+ ++ ++L+E ++P +IG L AG VS ++ Sbjct: 594 FVCLQSIIDVLIECDVRPSNIIGTGL----AGMVSDIYN 628 Score = 278 bits (711), Expect = 4e-72, Method: Compositional matrix adjust. Identities = 195/705 (27%), Positives = 343/705 (48%), Gaps = 62/705 (8%) Query: 826 IGTSKVSEQHHLYDRIGKLWQYGYSADWNTFSPQGRR--IPLPTYAFMRKKFWLEEPSFP 883 I +++ Q+ L + +G+ W+ G +W+ + R I LPTY F +K++W++ Sbjct: 683 INNNQIILQNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQQ 742 Query: 884 GRAGSQPYRMN-RKNIEEWYYVPSW--KRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKF 940 S+ + R NI EW+Y P W K + VT+ +S + L+F D+ G Sbjct: 743 NITNSEETSIKKRSNIAEWFYTPGWMEKEIVDVTK------ESTKSWLLFLDNEHIGLAL 796 Query: 941 TDKWKTVSEGSVTVYKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWS 1000 +K + +TV G K S +E I P + EDY LF EL +P+E++HLW+ Sbjct: 797 KEKLERDGHRVITVGVGPSYKKISLNEFTICPTKQEDYYQLFNELQKQECLPEEIVHLWN 856 Query: 1001 LPFDQKEAHALVPDAGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSP 1060 + D K+ + LD G++SL+++AK + +P+ + V+TN + +V+GD++ Sbjct: 857 V--DNKD----LGIETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIA 910 Query: 1061 HKATMLGPVKVIPLEYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNN 1120 K+T+L P+KV P EYP+IRC +D +L D + +I +L S++ ++V A RNN Sbjct: 911 EKSTLLAPIKVFPQEYPNIRCRSVDF-MLSDNE--EALISNLYSEIQTDIIDTVIAIRNN 967 Query: 1121 SFWVPTCNAVTLDTRHAM-------------KIQPHGKYLITXXXXXXXXXXXXXXXRQA 1167 + ++ + + M I+ G YLIT R Sbjct: 968 TRYIRIYEPIPDEKVSEMLVINENELASKIPNIRSEGIYLITGGMGGVGLKLAEYLARTV 1027 Query: 1168 RVELILAGRTPFPPKEEW-----AEWSAPHLAEEIQKLTEIENSGGTVHVLQADISNPAE 1222 + +LIL RT P +EEW ++ L + I + ++E+ G V AD+++ + Sbjct: 1028 KAKLILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQ 1087 Query: 1223 VQALLTQVEHTVGELTGVIHAAGVADGELIQ----RSTRESSKNMLAAKVDGTLCLYEAL 1278 ++ ++ Q E G + GVIHAAGV + Q + +R + KV G L L + L Sbjct: 1088 MRNVIHQTEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLL 1147 Query: 1279 RGKPLDFFILCSSLSSYLPAIGQAGYCAANAFLDSFA-FYAHAQNPGFPVLSVNWERWKQ 1337 LDF L SSLS L +G Y AAN +LDSF+ ++ N + S+NW W+ Sbjct: 1148 SNYDLDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT--SINWGDWQY 1205 Query: 1338 TGMSRRIEALHKELTGSELEDTITEGEGIQIFSRIGNLA-VPQIIISAFDMNERVQLYEL 1396 TG ++++ + + LE +T EG + F + L+ + Q+IIS+ D+N+R + Sbjct: 1206 TG-AQQVNKIFNAQSIEALE--MTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQW-- 1260 Query: 1397 AGSPLDFEGAESISHQQPVAGIFERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDD 1456 ++ + IS E + T + ++E E + +W+ + V V +++ Sbjct: 1261 ----INLNSRKRISE-------LETQTKTGDKFRNQDEVEEIIIGIWKEFYSVDTVNVNE 1309 Query: 1457 SLFELGGDSLMALSILARVQKQWNERIPMAYFINHPTVAGISSYM 1501 + F+LG SL + I R+ + ++I + +P++ ++ Y+ Sbjct: 1310 NFFDLGATSLHIIQIHERLINRLEKQISIGVMFEYPSIRSLARYL 1354 >B5UXK2.1 B5UXK2_BACCE Beta-ketoacyl synthase Length = 3336 Score = 1231 bits (3185), Expect = 0.0, Method: Compositional matrix adjust. Identities = 668/1729 (38%), Positives = 1008/1729 (58%), Gaps = 56/1729 (3%) Query: 11 EIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAGAV 70 +IA+IG+ RFPGA N +FWNN+K G ES+ FTDEEL GV + + NYVKA Sbjct: 1376 DIAIIGIDGRFPGAQNVNEFWNNIKSGTESIQFFTDEELIESGVNPMEVKSPNYVKAKGY 1435 Query: 71 LDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGASSN 130 L+ + FD FF Y+P+DA +MDPQ+R+FHE AW +LE AGY +TYPGLIGV++GAS N Sbjct: 1436 LEGTDNFDAPFFDYTPQDASLMDPQLRVFHECAWSALEHAGYNIETYPGLIGVYSGASPN 1495 Query: 131 YNWNA-RVYSYEGEHRDAFSEIQLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXIHT 189 W S E F L++KD L+++ISYKFNLKGPSM IH Sbjct: 1496 LYWQVLSTLSEANEPAGQFLISLLNDKDSLSTQISYKFNLKGPSMNIFTGCSTSLVAIHN 1555 Query: 190 ACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGTGA 249 AC++LL G CD+AIAGG ++ P ++GY YQEG S DGH R FDE A+G+LFG+G G Sbjct: 1556 ACQALLQGHCDIAIAGGITLTQPEKAGYTYQEGMLFSSDGHCRPFDENANGMLFGDGVGI 1615 Query: 250 VVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGPDS 309 VVLKPL+ A+ D D I AV+KG+A+NNDGNRK GY APSVEGQ EVI+ A + V P+S Sbjct: 1616 VVLKPLQEAINDGDTIHAVIKGTAINNDGNRKIGYTAPSVEGQVEVIKMAQHEANVEPES 1675 Query: 310 ISYIETHGTGTQLGDTIEFTALQQVFHTRQSPCI-LGSVKNNIGHLDAASGVAGFMKAVL 368 ISYIETHGT T+LGDTIE AL +VF++ + + +GSVK N+GHL+AASGVAG +K V Sbjct: 1676 ISYIETHGTATKLGDTIEIKALSEVFNSNEKQSVPIGSVKANVGHLNAASGVAGLIKTVF 1735 Query: 369 ALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYPLRAGVSSFGVGGMNAHLI 428 A+K + +PP VNF K N + EK PF VN +L +W + PLRAGVSSFG+GG NAH+I Sbjct: 1736 AMKDQVLPPSVNFTKPNTQIGFEKTPFYVNQRLNEWKKDNKPLRAGVSSFGIGGTNAHII 1795 Query: 429 LEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTLQAGR 488 LE+AP +E Q++++SA+S ++L+ MT NL H+E++P + + D +YTLQ GR Sbjct: 1796 LEEAP-KLEATSNSRPYQMLMISAKSKDALDRMTLNLGNHLEQNPHVNLADTSYTLQIGR 1854 Query: 489 KPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMGRELY 548 K F+ R+ L+C ++ IE L + + R+ Q V E ++ F+F G G+QYVNMG ELY Sbjct: 1855 KEFKHRRALVCSSTQEGIELLNQPEGRRVQYVNVKEEHPKVNFLFSGNGSQYVNMGLELY 1914 Query: 549 HNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLVILFIFGYAL 608 E IFR+ +D+CFAILQ + + + +L+P+ ++A E + R++ S ILF F YA+ Sbjct: 1915 EQEAIFREAMDECFAILQSVTNVNMKEVLYPTTFSIDEATEKLKRMEFSQPILFAFEYAV 1974 Query: 609 AELLMEWGIKPDVVIGYSLGEYIAGTVSGLFTLEQAIPLVLKRGRLFQQLPDGIMLSIPL 668 A+LLM WGIKP+ +IGYS GEY+A ++ +FTLE A+ LV+KRG+L LP G+MLS+PL Sbjct: 1975 AKLLMGWGIKPEAMIGYSFGEYVAACLAEVFTLEDALKLVVKRGQLMSSLPAGVMLSVPL 2034 Query: 669 PPDKVLPLLGD-------SLEIAIDNQVSCVVGGPAHLVLELEEKLKQSKCVCTPLPTAK 721 P ++++ L+ ++ +A+ N +C+V G +++ E +LK+ + +C + Sbjct: 2035 PEEELIHLINSFEKEYQHTISLAVVNGPACIVSGTEEAIVDFENELKKQRLMCMRVTIEG 2094 Query: 722 VIHTSRVESILDEYRAALQPVQYQPMKLRFMSSVTGDWAGPEELATSQYWIDQLQEKVSF 781 H+ ++SILDEY + + + + K+ ++S++TG W PEE YW+ ++ V F Sbjct: 2095 AAHSHELDSILDEYASYVSTLTLREPKIPYLSNLTGTWIRPEEATNPVYWVKHMRGTVRF 2154 Query: 782 VKAVQRLA-DTRTLFIEIGPGHDLSALVKRTFG-QGPNVQVLNLIPIGTSKVSEQHHLYD 839 +Q L D +LFIEIGPG+DLS L R + N ++ N + VS+ + L+ Sbjct: 2155 SDGIQELNRDNTSLFIEIGPGNDLSRLTSRLLDYENGNERIFNTVRSVQQDVSDMYFLFS 2214 Query: 840 RIGKLWQYGYSADWNTF--SPQGRRIPLPTYAFMRKKFWLEEPSFP--GRAGSQPYRMNR 895 I ++W G S DW F + RRIPLP Y+F + + L+ + + S+ ++++ Sbjct: 2215 HITRMWVTGISVDWEQFYKDEKRRRIPLPMYSFNKISYKLQGNPYDLGQKLNSKQSKISK 2274 Query: 896 -KNIEEWYYVPSWKRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKFTDKWKTVSEGSVTV 954 NI EW+Y P WK T P+ +E ++F D G + + VTV Sbjct: 2275 NNNISEWFYTPQWKSSTLF---EPNHDVNE-TWIVFVDQEGLGNELVKDLLNKGQRVVTV 2330 Query: 955 YKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWSLPFDQKEAHALVPD 1014 G K + D +INP DY L E+ +P +IH+W + ++++A + Sbjct: 2331 EPGFAFNKENNDRFIINPEERTDYVKLLDEVQEIYGLPTRIIHMWGITNEERQASIEYVN 2390 Query: 1015 AGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSPHKATMLGPVKVIPL 1074 + G++S+ + +A G + +R+ITNGV +V+GD+ P K+T+LG V+P Sbjct: 2391 CKQNLGFYSMFYLTQALGDKNISDSISIRIITNGVQQVIGDEELIPEKSTVLGTSLVVPQ 2450 Query: 1075 EYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNNSFWVPTCNAVTLD- 1133 EY + CS +D+ L + +I+ LV + + + + AYR N +V T + L+ Sbjct: 2451 EYSYLSCSSVDVVLPLNKEWKSRLINQLVEECLSNTNDKMIAYRGNKRFVQTYEPLQLEQ 2510 Query: 1134 -TRHAMKIQPHGKYLITXXXXXXXXXXXXXXXRQARVELILAGRTPFPPKEEWAEWSAPH 1192 + + ++ +G YLIT + + L+L RT P ++EW H Sbjct: 2511 PAKEKLPLRKNGVYLITGGLGGIGTILAKHLAQTVQANLVLLTRTGLPNRDEW----DMH 2566 Query: 1193 LAEE------IQKLTEIENSGGTVHVLQADISNPAEVQALLTQVEHTVGELTGVIHAAGV 1246 L E I+K+ EIE +G V+VL AD+++ +++ + + E G++ GVIH AG+ Sbjct: 2567 LKENTMYSDRIRKVLEIEETGSKVYVLAADVTDQSQLYEAIHKAEQKFGKINGVIHGAGI 2626 Query: 1247 ADGE---LIQRSTRESSKNMLAAKVDGTLCLYEALRGKPLDFFILCSSLSSYLPAIGQAG 1303 G+ LIQ +E + +AK+ G L L E LR K LDF +L SS+S+ L +G Sbjct: 2627 LGGKTFNLIQELEKEDCEEQFSAKIYGLLNLEECLRNKDLDFCVLMSSISAVLGGLGYVS 2686 Query: 1304 YCAANAFLDSFAFYAHAQNPGFPVLSVNWERWKQTGMSRRIEALHKELTGSELEDTITEG 1363 Y A+N ++D FA Y + + P +SVNW WK E ++ S E ++T Sbjct: 2687 YAASNIYMDVFAQYIN-RYSNLPWISVNWSDWKY----WEDEEKDMQIGASVHELSMTPE 2741 Query: 1364 EGIQIFSRIGNLAVPQIII-SAFDMNERVQLYELAGSPLDFEGAE---SISHQQPVAGIF 1419 EG+Q F+ + +++I S ++ R+ + L S D + E ++ H Sbjct: 2742 EGVQAFNIALSWKQGEVLIHSPGELQARIDQWVLLNSFNDEKEEELDSTLYHS------- 2794 Query: 1420 ERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMDDSLFELGGDSLMALSILARVQKQW 1479 RP L TEYV PRNE E +L+++W F V VG+ D L ELGGDSL A++I++++ K++ Sbjct: 2795 -RPQLLTEYVAPRNEVEEKLSKIWRNIFKVSEVGVHDDLLELGGDSLKAITIVSKIHKEF 2853 Query: 1480 NERIPMAYFINHPTVAGISSYMEQATPTESSGVKPVARREYYPLTSVQKRVYFLQKMHST 1539 N +P+ + +++Y+ +A +E + P + YY L+S QKR Y L +++ Sbjct: 2854 NVEVPIKELFTLSNIEKLANYISRADKSEFDVIVPAEPKSYYQLSSAQKRFYVLHRLYPE 2913 Query: 1540 TTVYNNPGIYQLESEIDTGXXXXXXXXXXXXHEILRTSFGFAGEEVVQRVHQNVVFSIEE 1599 +T YN+ + L +++ HEI RT+ ++ VQ +H + F I + Sbjct: 2914 STAYNDTSVILLNGKLNIERLEKAFTQLIKRHEIFRTTIEMKNDKPVQIIHDHADFHITQ 2973 Query: 1600 LDGHEAGMDAVIAGFIRPFELEKAPLLRVGYLR---DKRILLIDMHHLVSDEMSYRLLIQ 1656 ++G E+ ++ +I FIRPF AP RVG +R K IL+ID+HH+V+D +SY + ++ Sbjct: 2974 IEGFESEVEQIINEFIRPFNFNNAPYFRVGLIRLEEQKHILIIDLHHIVTDGVSYDIFVR 3033 Query: 1657 DFLALYEGKDLTVLPLQYKDYAAWQSGMKGSPAFVSQQQYWLDQFADGA 1705 D ALY G+ L L +QYKDY+ WQ K + +QYWL++F DG Sbjct: 3034 DLFALYSGEKLPNLKIQYKDYSEWQQSEKEKEIALKHEQYWLEEFKDGV 3082 Score = 538 bits (1385), Expect = e-150, Method: Compositional matrix adjust. Identities = 275/639 (43%), Positives = 400/639 (62%), Gaps = 29/639 (4%) Query: 9 GLEIAVIGLACRFPGADNREQFWNNLKDGLESVTVFTDEELRREGVTAEFLSNENYVKAG 68 GLEIA+IG+A +FPGA+ QFW+NLK+G++S++ FT++EL +EGV + L + N+VKA Sbjct: 10 GLEIAIIGMAGKFPGANEINQFWDNLKNGVDSISTFTEDELIKEGVNLDVLQHPNFVKAK 69 Query: 69 AVLDRFEYFDERFFGYSPKDALVMDPQVRLFHEVAWESLEDAGYVPDTYPGLIGVFAGAS 128 L+ EYFDE FF Y+P++A +MDPQ+R+ E WE+LE AGY P Y GLIG++ GAS Sbjct: 70 GYLEEVEYFDESFFAYTPREAKIMDPQIRMLQETTWEALEMAGYNPFDYEGLIGLYVGAS 129 Query: 129 SNYNWNARVYSYEGEHRDAFSEI-QLSNKDFLASRISYKFNLKGPSMXXXXXXXXXXXXI 187 +N+NW + FSE LS KD +++ SYK LKGPS I Sbjct: 130 TNFNWMKHTPLLNSDSVVEFSEAGTLSYKDAISTLTSYKLGLKGPSFTLYTACSTSLLSI 189 Query: 188 HTACRSLLSGECDMAIAGGSSILIPHRSGYLYQEGHFLSKDGHIRAFDEQASGILFGNGT 247 H ACRSLL+GEC +A AGG SI P ++GY Y EG S DG +R FD +A G +F +G Sbjct: 190 HLACRSLLTGECSIAAAGGVSITYPKKNGYKYHEGMTSSPDGKVRTFDAEAQGAVFSDGV 249 Query: 248 GAVVLKPLENALADKDHIWAVVKGSAVNNDGNRKAGYMAPSVEGQREVIESALQVSEVGP 307 G V+LK LE+A+AD D I+ V+KGSA NNDG RK GY APSVEGQ EVI++A +EV P Sbjct: 250 GMVILKRLEDAIADGDTIYGVIKGSAANNDGGRKVGYTAPSVEGQAEVIQAAHSFAEVDP 309 Query: 308 DSISYIETHGTGTQLGDTIEFTALQQVFH--TRQSPCILGSVKNNIGHLDAASGVAGFMK 365 +ISY+ETHGT T LGD+IE AL++ F ++S C +GSVK+N+GHLD A+GV G +K Sbjct: 310 STISYVETHGTATPLGDSIEVEALKRAFQDVDKKSFCAIGSVKSNVGHLDTAAGVTGLIK 369 Query: 366 AVLALKHRQIPPMVNFAKSNPLLEMEKYPFAVNTKLLDWPLSSYP-LRAGVSSFGVGGMN 424 VL+++H+Q+PP +N + N ++ PF +NT L++W LRAGVS+FG GG N Sbjct: 370 TVLSMRHKQLPPTLNVKRPNSKIDFIDSPFYINTDLVNWQSEDKDLLRAGVSAFGYGGTN 429 Query: 425 AHLILEQAPLPVEEPEEDLQPQLILLSAQSMESLENMTENLARHVEEHPDIRIRDVAYTL 484 H++LE+AP V+ + +L++LSA+S E+L N T N+ +++E + D+ + DVAYTL Sbjct: 430 VHIVLEEAP-KVKSSASTREKKLMVLSARSKEALNNATVNMVQYLESNKDVELADVAYTL 488 Query: 485 QAGRKPFEFRKQLICRDRKQLIEGLRKKDARQPQVNRVGEAPEQIVFMFPGQGAQYVNMG 544 Q GR+ F +R+ ++C+D I+ L K + V + E P+ +VF+ P + + + Sbjct: 489 QTGRRSFPYRRAVLCKDIDSAIDNL--KTVKDFHV-KTQENPD-LVFVLPSEYSSIIENV 544 Query: 545 RELYHNEPIFRKYLDQCFAILQVHSETDYRAILFPSEEEAEQAREFMARLDHSLV---IL 601 +ELY EP+F K ++ Q+++ + F D SLV Sbjct: 545 KELYQKEPLFLKVFERNMTDAQMYTGKALKEAFFKG-------------TDDSLVEDLTF 591 Query: 602 FIFGYALAELLMEWGIKPDVVIGYSLGEYIAGTVSGLFT 640 F+ ++ ++L+E ++P +IG L AG +S ++ Sbjct: 592 FVCLQSIIDVLIECDVRPSNIIGTGL----AGMISDIYN 626 Score = 275 bits (703), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 195/706 (27%), Positives = 337/706 (47%), Gaps = 64/706 (9%) Query: 826 IGTSKVSEQHHLYDRIGKLWQYGYSADWNTFSPQGRR--IPLPTYAFMRKKFWLEEPSFP 883 I +++ Q+ L + +G+ W+ G +W+ + R I LPTY F +K++W++ Sbjct: 681 INNNQIILQNDLLEVLGQAWELGVEINWSKLYEEEYRLRIALPTYPFEKKRYWIDPAEQQ 740 Query: 884 GRAGSQPYRMN-RKNIEEWYYVPSW--KRLTPVTQAAPSQAKSERRRLIFGDHSSAGQKF 940 S+ + R NI EW+Y P W K + V + S + L+F D+ G Sbjct: 741 NITNSEETSIKKRSNIAEWFYTPGWMEKEIVDVIKG------STKSWLLFLDNEHIGLAL 794 Query: 941 TDKWKTVSEGSVTVYKGEKRAKWSADELVINPARDEDYEWLFQELHAGSFIPDEMIHLWS 1000 +K + +TV G K S +E I P EDY LF EL +P+E++HLW+ Sbjct: 795 KEKLERDGHRVITVGVGPSYKKISLNEFTICPTEQEDYYQLFNELQKQECLPEEIVHLWN 854 Query: 1001 LPFDQKEAHALVPDAGLDDGYFSLLAIAKACGQHLGEHPLELRVITNGVCEVMGDDATSP 1060 + D K+ + LD G++SL+++AK + +P+ + V+TN + +V+GD++ Sbjct: 855 V--DNKD----LGIETLDTGFYSLISLAKTISKFNLLYPININVMTNNMQKVVGDESIIA 908 Query: 1061 HKATMLGPVKVIPLEYPSIRCSLLDMELLPDGSRLDNMIDSLVSQLAAAKWESVAAYRNN 1120 K+T+L P+KV P EYP+IRC +D +L D + +I +L S++ ++V A RNN Sbjct: 909 EKSTLLAPIKVFPQEYPNIRCRSVDF-MLSDNE--EALISNLYSEIQTDIIDTVIAIRNN 965 Query: 1121 SFWVPTCNAVTLDTRHAM-------------KIQPHGKYLITXXXXXXXXXXXXXXXRQA 1167 + ++ + + M I+ G YLIT R Sbjct: 966 TRYIRIYEPIPDEKVSEMLVIKENESASKIPNIRSEGVYLITGGMGGVGLKLAEYLARTV 1025 Query: 1168 RVELILAGRTPFPPKEEW-----AEWSAPHLAEEIQKLTEIENSGGTVHVLQADISNPAE 1222 + +LIL RT P +EEW ++ L + I + ++E+ G V AD+++ + Sbjct: 1026 KAKLILVSRTALPDREEWDQILQSQIENEQLCQRINHIQKLESLGAKVMTAVADVADEEQ 1085 Query: 1223 VQALLTQVEHTVGELTGVIHAAGVADGELIQ----RSTRESSKNMLAAKVDGTLCLYEAL 1278 ++ ++ Q E G + GVIHAAGV + Q + +R + KV G L L + L Sbjct: 1086 MRNVIHQAEANFGHINGVIHAAGVLRVKSAQCPMEKISRIECEEQFLPKVHGVLVLDKLL 1145 Query: 1279 RGKPLDFFILCSSLSSYLPAIGQAGYCAANAFLDSFA-FYAHAQNPGFPVLSVNWERWKQ 1337 LDF L SSLS L +G Y AAN +LDSF+ ++ N + S+NW W+ Sbjct: 1146 SNYDLDFCYLVSSLSPILGGLGFVAYSAANLYLDSFSDKVSNTSNNRWT--SINWGDWQY 1203 Query: 1338 TGMSRRIEALHKELTGSELED-TITEGEGIQIFSRIGNLA-VPQIIISAFDMNERVQLYE 1395 TG E ++K +E +T EG + F + L+ + Q+IIS+ D+N+R + Sbjct: 1204 TGT----EQVNKIFNAQSIEALEMTSEEGQKTFQCVLGLSGLNQVIISSGDLNKRFDQW- 1258 Query: 1396 LAGSPLDFEGAESISHQQPVAGIFERPSLTTEYVPPRNERERELAQLWEAQFGVQPVGMD 1455 ++ + IS E + T + ++E E + +W+ + V V ++ Sbjct: 1259 -----INLNSRKRISE-------LETQTKTGDKFRNQDEVEEIIIGIWKEFYSVDTVNVN 1306 Query: 1456 DSLFELGGDSLMALSILARVQKQWNERIPMAYFINHPTVAGISSYM 1501 ++ F+LG SL + I R+ + + I + +P++ ++ Y+ Sbjct: 1307 ENFFDLGATSLHIIQIHERLINRLEKHISIGVMFEYPSIHSLAKYL 1352 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.405 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 10,386,086,507 Number of extensions: 447975795 Number of successful extensions: 1136829 Number of sequences better than 1.0e-05: 12726 Number of HSP's gapped: 1076794 Number of HSP's successfully gapped: 18748 Length of query: 1728 Length of database: 3,060,696,203 Length adjustment: 150 Effective length of query: 1578 Effective length of database: 1,647,543,953 Effective search space: 2599824357834 Effective search space used: 2599824357834 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 139 (58.2 bits)