BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0489.0003.p (2437 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I5H5.1 B8I5H5_CLOCE Amino acid adenylation domain protein 1492 0.0 B8I5I0.1 B8I5I0_CLOCE Condensation domain protein 1030 0.0 C3HA42.1 C3HA42_BACTU Beta-ketoacyl synthase 1023 0.0 B8I5H4.1 B8I5H4_CLOCE Beta-ketoacyl synthase 913 0.0 C3HA41.1 C3HA41_BACTU Beta-ketoacyl synthase 815 0.0 >B8I5H5.1 B8I5H5_CLOCE Amino acid adenylation domain protein Length = 3695 Score = 1492 bits (3863), Expect = 0.0, Method: Compositional matrix adjust. Identities = 816/2428 (33%), Positives = 1336/2428 (55%), Gaps = 97/2428 (3%) Query: 40 ENRTADDIAIIGIACRFPFADTLEQYWDNLLNGINGITDFPLKRRKDIDPLLQKV---ME 96 E + D+AIIGI+ +F +++++ +L NG N + FP +R++DID +L+ + + Sbjct: 25 EEVSTQDVAIIGISGKFASCGNMDEFYVSLRNGDNLVGKFPQRRKQDIDTILRYMGISEK 84 Query: 97 TPVYGKGSYLEQVDSFDAEYFRLSPKEAEFMDPHQRLMLEVAAEAIEDAGYMGEKIYGTQ 156 VY +G++L ++D FD F +SPKEA MDP+QRL L+ A AIED+GY G+++ ++ Sbjct: 85 ETVYYEGAFLNEIDKFDCSLFNISPKEAGLMDPNQRLFLQTAWNAIEDSGYGGDRLRSSR 144 Query: 157 TGVFIGRDHHSSGLYQQFID----SSNELAMTGNLPSFISGRIAFFFNLTGPNQVIDTAC 212 TGV++G + Y++++ S L++TGN+ S ++ RI++ +L GP+ ++DTAC Sbjct: 145 TGVYVGYCGDFNEDYRKYVQLMDPSMAALSVTGNIKSIVASRISYLLDLKGPSMLVDTAC 204 Query: 213 SSGLVALHQGCESLRHKECTMAIVGGISLNLLPLANSSFKIV--ENNDGKVRPFDKNATG 270 SS LVA+H C++LR EC AI GG+ L LLP+ N+ + E++ G R FD+ + G Sbjct: 205 SSTLVAIHLACQALRKGECETAIAGGVKLILLPVDNNPQNGIGIESSSGVTRSFDEYSDG 264 Query: 271 TTWGEGLSAIMIKPLREALKDKDRIYSVVKGSGVNSDGASNYITAPNPEAQERLLIDVWT 330 T +GEG++AI++KPL++A++D+D IYS++KGS VN DG S IT PN +AQ ++I W Sbjct: 265 TGFGEGVAAIVLKPLKKAIEDRDNIYSIIKGSAVNQDGTSMGITVPNAQAQSDVIIRAWK 324 Query: 331 KAGVHPETISYIETHGTGTVIGDPIEVKAMKQAFDQYTNKKQFCGLGSVKSNIGHLVGAS 390 A + PETISYIE HGTGT +GDP+E+ ++ AF QYTNKKQFC + SVK+NIGHL A+ Sbjct: 325 DAKIDPETISYIEAHGTGTNLGDPVEIDGIEMAFAQYTNKKQFCAVSSVKTNIGHLDSAA 384 Query: 391 GMASLIKVILSMKHRQLVPTIHFEEPNPYIPFSQSPFYMVDKPLAWEAAQGPRRAGISSF 450 G+A L+K +LS+KH++L P++HF+ PN I F SP Y+ D WE GPRR GISSF Sbjct: 385 GIAGLLKAVLSLKHKELFPSLHFDRPNQKINFQNSPVYINDSLEQWENHGGPRRCGISSF 444 Query: 451 GFSGMNCHVLLEEWQQEDQQTVREEPEQP-----RIFPVSAKTKSGLLELLQRYSQFLQT 505 G SG NCH++LEE Q ++ PE+ IF +S++ +GL+E L+ Y ++L Sbjct: 445 GLSGTNCHLVLEEPPQ-----IKSIPEESPGCNYHIFTLSSQNINGLMEQLKNYEKYLNR 499 Query: 506 HQRADFQNLVYTAQLGREHFAHRLAIIAKDASELWRKIAAVLLNDVDQLPESIGYYGYFP 565 + +L T GR H+ RLA + +EL KI + ++ + Y+G Sbjct: 500 EREVSLGSLCSTTNTGRGHYNFRLAFVITSKNELKEKIQKLSTGGLENFEKYGVYFGKHK 559 Query: 566 IRQKAKNNMAQQDLSEAKTRAAYDKARRLVRQIAENPAQAAEGSLEELAQLYVQGTRVDW 625 I K K + + S+ + + + + N +Q + SLE + LYV G V W Sbjct: 560 IVDKEKESRGNNEYSQEEIADLSLQTETYLNEAINNESQQKKVSLENICALYVNGANVQW 619 Query: 626 NALWTGQAVQTARLPVYPFTKTRHWPAPAPTEGAFPGVPGPLLGECTVKTAGMRIYAATL 685 N L+ + LP Y F K R W + PL+ + +++ + +++ T Sbjct: 620 NRLYKSGSYAKVSLPGYSFMKKRCWIEHENSNSH--NSKHPLIDKHILESVDLDVFSTTF 677 Query: 686 SGKEHWLLQEHRILGNGVWPGVAYLEMAKAASGYFFAGENVVLRQVTLQNMLICPPDETR 745 W+L EH+I N V PG YLEM + AS F + ++QVT + LI DE + Sbjct: 678 KVDRQWVLNEHQIGSNYVAPGTTYLEMIREASRKHFGNHPLKMQQVTFIHPLILKADEEK 737 Query: 746 VVHTIIREEQDHAAFTIAS-MKEGGHTENWIIHAQGEI--YPQAEPKMPVIALEPLIQVM 802 VHTII+ ++D +TIAS KE G W+ H+ G + P+ + E + Sbjct: 738 EVHTIIKRDEDTLEYTIASKQKENGQ---WLKHSTGAVAGIPKEDASSLSFDFEKI---- 790 Query: 803 NEESVELFTPILTAG-----IQYGPSWKCIRRFYQNE--SAAVLHIGSTDGASAREPFSL 855 +E+ I G ++ GP W ++ Y + + A +G + + + + Sbjct: 791 -KEACPNVIDIGNMGSREGILRLGPRWDTLKAMYTGDRMALACFELGE-EYSEDLSKYHM 848 Query: 856 HPALMDTALSFWHLLRQREEAADLPAFPFYYESIRIFGVMPASFFSYVRKRETHGDHRET 915 +P+LMD A++ ++ + P Y S++I+ +P SF+SY+ +++ + E Sbjct: 849 YPSLMDCAVNIANM-----SVGEGLYLPLSYGSLKIYETLPRSFYSYLVRKDNMSLNNEI 903 Query: 916 ASYDISLIDEAGNVFAEVENYTLKKV-SPALISKD---LFYRINWVKSPR---PDGGSRI 968 A +DI L+DE G AE+E+Y++KKV + L ++D LFY+ W K + + Sbjct: 904 AIFDIKLMDEYGKALAEIEDYSVKKVHNTGLEAEDPDNLFYKTGWEKQEQEFLTGENADF 963 Query: 969 GGTVLLFGNDCRATREFIRHMEAGDVELIQVVQGEAYRKEKDSRYVVGNAAADYIQLFAD 1028 G ++F ++ E + + A E ++V G +R+ S+Y+ G D+ +LF++ Sbjct: 964 SGVTIIFNDEYGMGEELAQKLRAAGTETVEVEFGIDFRQINHSKYMTGTDEGDFRKLFSE 1023 Query: 1029 LQGRNVSRMIHGYALDEDSGADSLSSLQAVQEKSVQSLFFIIKALVQAKYKEQIELVLLG 1088 L GR V+R+I+ AL+ D+ D + L E+ V +L + KA+ ++ + ++LV++ Sbjct: 1024 LNGRAVNRIIYLSALNFDTDMD-IDGLDEAMERGVYNLHRLTKAISES-MQNDLDLVIIA 1081 Query: 1089 KQGYEVTGGEKELEPCYAAFYNLGKVADTEYPNLKCRSIDLGDETEWGAVLEEIFGERTA 1148 EV ++++ + Y +G+V EY N++CR ID+ + ++ E+ ++ Sbjct: 1082 DNASEVVEYQEKINALSGSLYAMGRVIGQEYDNIRCRCIDIDKAVDTDLIISELAQKKFL 1141 Query: 1149 NQVAYRENKRFIXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXXXXXELARYXXXXXXXX 1207 V+YR +R+I E+ RY Sbjct: 1142 FNVSYRNGQRYIQNLQRQSPYSNGGDKIQIREEGVYIVAGGLGGIGLEICRYLAAEKRVN 1201 Query: 1208 XXXXXXXXXPPREAWEDIRQS------GTEPGTSRKIELLEEIERSGSQVMICPCDISDG 1261 P R W+D+ ++ T+ +I+ ++E++ GS+V+ D++D Sbjct: 1202 LVMINRSPLPERSLWDDLLKNTYEGINDTDYNIIDRIQSIKELKDMGSKVLCFSADLADM 1261 Query: 1262 QQLKHCLMQLREAYGPVKXXXXXXXXXXSGYLFTKDWSDFTRVTAPKIEGTYLLYSLLQ- 1320 ++ L ++R+ + + G L KD RV APK+ GT +L L + Sbjct: 1262 ASVRLVLDEVRKHHANINGVINLAGVFEEGILIKKDTEALKRVIAPKVNGTLILDRLTEN 1321 Query: 1321 EQPDFFVLFSSIATLEGSPGQGDYAAGNGYLDGFAHFLRRKGVRGLTLNWAAWEETGMAL 1380 + DFFV+FSSIA+ G GQG+Y+A N ++D FA + R G + +++NW W + GMA Sbjct: 1322 DNLDFFVMFSSIASFIGGHGQGEYSAANAFMDSFAEYKNRTGRKVISINWTGWNQVGMAS 1381 Query: 1381 D-NGALGSKIYRPLKTGTAVHAFSRALQLEEPRVIIADIRLDQLDESVTGKLPLQLSPDL 1439 N + G +I++ + A+ AF RAL PRV+I ++ + + E +QLS ++ Sbjct: 1382 QYNLSDGRRIFKLISKEKAIKAFDRALTASLPRVVIGELDYEFMAEYAMDNAYIQLSQEI 1441 Query: 1440 RRTGNRFAQ-PRPVAAAADTIAII--GHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFY 1496 + + + + P+ V ++ G + ME+ VA +W + GL+++DI +N Y Sbjct: 1442 KNSLKPYIKMPQQVKQPGKRKIVLPKGRQNQEYTPMEKGVAAVWGEVLGLEEIDIYENLY 1501 Query: 1497 ELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKAAGSE 1556 LGGDSI+A ++AN +N +L+ + I+++FEY TV LAA+LE P + + SE Sbjct: 1502 NLGGDSIIALRIANEINKKLNASIRISDLFEYLTVQRLAAFLEDKTPEKEVSVKDLRESE 1561 Query: 1557 APNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLR 1616 + Y+LS Q RIWFLQNYDPQ T Y+LP+V I +++ VL++ +++L +RH LR Sbjct: 1562 KEHTYYELSNIQKRIWFLQNYDPQMTVYNLPLVSSINAELNVQVLKEAVNLLIQRHEVLR 1621 Query: 1617 TIIKNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQNLFRAEL 1676 T+ NG P Q ++ + D EPH N F L R + Sbjct: 1622 TVFGEENGEPYQKILTVYEYEPEVVDLTGEPHKESVLNELIAQENKKPFNLSNPPMRVVV 1681 Query: 1677 HRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQE 1736 ++ S Y LY+N+HHI++DGWSMG+F E M+LY+ I ++ ++L P+ + DWV+Q+ Sbjct: 1682 YKLSSSSYCLYLNIHHIVTDGWSMGIFSYELMKLYEGIVLEKVVELEPLNFRYTDWVKQQ 1741 Query: 1737 KLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVTGQLRL 1796 W S +++ ME YW++EL +PLPVL LP DY RP Y+GS+IKF++ T +L+ Sbjct: 1742 LEWQDSSEFVEMENYWLQELYKPLPVLNLPVDYKRPQMQTYNGSFIKFSIDGNTTAKLKE 1801 Query: 1797 LAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCIRVD 1856 A+ + TL M +L+ YF+ LKK++ ++DI+VG PV+GRE +E ENI+G+F+N + IR++ Sbjct: 1802 FARQHNITLNMALLSAYFVLLKKITADKDIVVGLPVTGRENKELENIMGVFINTLSIRIN 1861 Query: 1857 FRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLYDNVPQ 1916 F +SS ++ V+ KCLKAY N +YPF+ ++ KLNPERD SR+P+FST+FQLYD +P Sbjct: 1862 FENISSLNDLITCVREKCLKAYRNIKYPFDLIISKLNPERDLSRSPIFSTVFQLYDKIPP 1921 Query: 1917 DNDRMSLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYLTHLINQVIADPEGQLS 1976 + + S+++LS +C+ + +IE+R EY T LF ++TI+ +A Y T++IN + + + + Sbjct: 1922 ETEGSSMFELSMLCREEDNRIEIRAEYNTDLFEKQTIERFAVYYTNIINAFLIESDMSID 1981 Query: 1977 RYELLDARHKAEIINQFHPLPVPMNPPDQVCRLFEAQVEQNPDQTAVVFEGERVSYRELD 2036 E+L II F+ + + LFE Q + P ++ +Y +++ Sbjct: 1982 GIEILSLEETNRIITLFNATEREYDRTASIDTLFELQAKALPHSQCIIQGNTIYTYAQIN 2041 Query: 2037 ELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILKSGRPYVPLDPDFPPERIAYM 2096 L+N +A L++ + VG+ + R +M+ +LGILK+G Y+P+DP++P ERI YM Sbjct: 2042 SLANCIARTLLEKGVMKGDIVGIMVERSCNMLVGILGILKAGAAYLPIDPEYPGERINYM 2101 Query: 2097 IRHSGLRTVVSDGASIPKLLELASDVLKAVIDVAGDSTPAGTADHLSCYKYSDIRKQPVA 2156 + S ++ +++ G L+ +D+ D G ++LS I +P Sbjct: 2102 LNDSSVKVLLTSGK-----LKGTVAFYGISVDMDDDGLYTGNCENLS------INNRP-- 2148 Query: 2157 RIPSKAASELMYIIYTSGSTGTPKGVMVSQPNVINYLLWSRQQFQLGPQHHMMLVTSISF 2216 L Y+IYTSGSTG PKGVM+ V N++ ++ + G ++ +TS+SF Sbjct: 2149 -------DSLAYVIYTSGSTGKPKGVMIEHQAVCNFIEGMVEKIEFGSGKSILALTSMSF 2201 Query: 2217 DISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQHKINFWHSVPVLMNQFLFGLSSQ 2276 DI + E L G + + S ++ +DP LL + Q+ I P + L Sbjct: 2202 DIFILETILPLCIGMKVVIASEEQQKDPKLLSEIIKQNSIEMLQMTPSRLQLLL-----S 2256 Query: 2277 DEKEIACLQHFDTVAIGGEAWSPKLAGDIRRSFPRAKLYNLYGPTEATIWATYYEAASDL 2336 D + + L + +GGEA+ L +++R A++YN+YGPTE TIW+T E L Sbjct: 2257 DSRGRSSLSVPQVLMVGGEAFPQALLDEVKRC-TNARIYNMYGPTETTIWSTIRE----L 2311 Query: 2337 TGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGEICISGAGVTPGYFRDEETTAGVFRTH 2396 T ++ + +G+PI+N +++I+ + GNL GIPGE+CISG G++ GY E T F + Sbjct: 2312 TDRSTIDIGKPIANTQVYIVSESGNLQPIGIPGELCISGDGLSRGYINRPELTLEKFLEN 2371 Query: 2397 PFT-DQIVYHTGDIGKYGMGGQLEYIAR 2423 P+ + +Y TGD K+ G +EYI R Sbjct: 2372 PYMPGKKMYRTGDFVKWLPDGNIEYIRR 2399 Score = 602 bits (1551), Expect = e-169, Method: Compositional matrix adjust. Identities = 353/1013 (34%), Positives = 552/1013 (54%), Gaps = 49/1013 (4%) Query: 1433 LQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDIS 1492 L L+P+ + +R A P PV +T + ++E E+A+ +++ +++ ++ Sbjct: 2481 LPLTPNGKT--DRKALPCPVLTGLNTNGFVD----AVNETEKALQRIYQDVLNIQRAGVN 2534 Query: 1493 KNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKA 1552 NF+ LGG S+ AT + + + +L ++ ++ +F+ PT+ LA + + S + Sbjct: 2535 DNFFALGGHSLKATILVSRIYKELGTEIPLSAVFKTPTIKELACSINGTDISEYQPIIPV 2594 Query: 1553 AGSEAPNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRH 1612 S + Y LS AQ RI+ ++ ++TAY++PV+ + D +Q + L RH Sbjct: 2595 EKS----SSYSLSPAQRRIYLMEAVTGESTAYNIPVLMDLEGEFDRERFEQAIKNLVARH 2650 Query: 1613 SSLRTIIKNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQN-L 1671 LRT V+G+P Q V I + + ++ F L+ L Sbjct: 2651 EILRTYFDAVDGVPVQIVQECMEPEIAYIEIKEDDSDGNIQNL------IKPFNLKSGPL 2704 Query: 1672 FRAELHRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVD 1731 FR ++ + + ++HHII DG S+G+ RE++ELY R +L + +Q D Sbjct: 2705 FRVKVLLTDNGRKTIMFDIHHIICDGISLGILTREFIELY------RGKELKELTVQYRD 2758 Query: 1732 WVEQEKLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIAYDGSYIKFTVSEEVT 1791 +V + GS Y E YWM + +PVL +P DY RP +Y+G + F +++E++ Sbjct: 2759 YVSWKSSLYGSERYKQQENYWMGMFSGDIPVLNMPADYTRPTVQSYEGDTVYFELNKEMS 2818 Query: 1792 GQLRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMV 1851 +L + + +T MT+LA++ + L K + +EDIIVG PV+GR + EN++G+F+N + Sbjct: 2819 KKLHEVETSEKTTASMTLLAVFNVLLYKYTGQEDIIVGMPVAGRGNADLENMLGVFINTL 2878 Query: 1852 CIRVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLY 1911 +R +F L+EV+ L AY N Y F LV+KLN RD SR+P+F +F + Sbjct: 2879 AMRNRPEGTKTFHNFLQEVRHNALNAYENQDYQFEELVDKLNVPRDLSRSPLFDVMFIMQ 2938 Query: 1912 D-NVPQD------------NDRMSLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYAC 1958 + + P+ + + S +DL+ + RLEY T +F ET++ + Sbjct: 2939 NTSFPEIEEEGLRFKSREFDSKSSKFDLTLESVEKENTLHFRLEYCTKIFMRETVERMSL 2998 Query: 1959 YLTHLINQVIADPEGQLSRYELLDARHKAEIINQFHPLPVPMNPPDQ--VCRLFEAQVEQ 2016 + +++ QV+ +P+ LS +++ K +I F+ V + V LFE Q E Sbjct: 2999 HFLNILEQVLNNPDITLSDIDIITKEEKEKIEGVFNATDVDFGDRGKLTVHELFERQAEF 3058 Query: 2017 NPDQTAVVFEGERVSYRELDELSNQLAAFLVQLEQEPAEPVGVYLGRGIHMIAVLLGILK 2076 PD AV+ EG ++Y EL+E +N+LA L + E VG+ + + I MI +LGILK Sbjct: 3059 RPDSIAVMCEGTGITYNELNEKANKLARLLQNEGIKREESVGIMVHKSIEMIIGMLGILK 3118 Query: 2077 SGRPYVPLDPDFPPERIAYMIRHSGLRTVVSDGASIPK--LLELASDVLKAVIDVAGDST 2134 +G YVP+DPD+P +RI YM++HS R ++ D +S K ++ + L+ VI++ S Sbjct: 3119 AGGAYVPVDPDYPADRIHYMLKHSQTRFLIIDQSSFEKTEMINTEENSLEVVINL---SE 3175 Query: 2135 PAGTADHLSCYKYSDIRKQPVARIPSKAA-SELMYIIYTSGSTGTPKGVMVSQPNVINYL 2193 AG L Y DI+ + +KA LMYIIYTSGSTG PKGV VS N +NYL Sbjct: 3176 GAGKTAGLIKYTAEDIKNLSPYNLKNKANPKNLMYIIYTSGSTGLPKGVGVSHANAVNYL 3235 Query: 2194 LWSRQQFQLGPQHHMMLVTSISFDISVFEIFGCLSSGATLHVVSSDRLRDPALLLAYMNQ 2253 WS + L + M LVTS+SFDISVFEIFG L SG L +V R++D +L + Y++ Sbjct: 3236 NWSIENMSLSHKDVMALVTSMSFDISVFEIFGSLLSGTCLCIVPDSRMKDGSLFMEYIDA 3295 Query: 2254 HKINFWHSVPVLMNQFLFGLSSQDEKEIACLQHFD---TVAIGGEAWSPKLAGDIRRSFP 2310 K+ WHSVP LM Q L + S+ K + + F + IGGEAW+ +LA DIR F Sbjct: 3296 GKVTIWHSVPALMIQLLTAVKSR--KTLGNQELFSRIRCIMIGGEAWTYELAKDIREYFH 3353 Query: 2311 RAKLYNLYGPTEATIWATYYEAASDLTGKTVVPLGQPISNNRIFILDKDGNLCGPGIPGE 2370 A++ N+YGPTEATIW T ++ + TV+P+G+PISNN++ ILD +C GIPG+ Sbjct: 3354 HARIVNMYGPTEATIWVTSHDVRDNPGSSTVIPIGKPISNNKVLILDSCKKMCPIGIPGD 3413 Query: 2371 ICISGAGVTPGYFRDEETTAGVFRTHPFTDQIVYHTGDIGKYGMGGQLEYIAR 2423 I ISG VT GY++DEE T VF + I+Y TGD+G+Y G +EY+ R Sbjct: 3414 IYISGLNVTRGYYKDEEKTREVFTLYGEKGSIIYRTGDVGRYLSDGTIEYLGR 3466 Score = 64.7 bits (156), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 50/72 (69%) Query: 1470 SEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYP 1529 SE+E+ +A +W++ +KK+ NF+ LGG+S++ QM ++++ + K+ + +IF+YP Sbjct: 3580 SEVERFLAGIWSQLLDMKKVGTKDNFFSLGGNSLLVNQMHSMIDEKYPGKIKVIDIFKYP 3639 Query: 1530 TVSGLAAYLEQS 1541 T+S LA ++E S Sbjct: 3640 TISKLADFMEGS 3651 >B8I5I0.1 B8I5I0_CLOCE Condensation domain protein Length = 2006 Score = 1030 bits (2663), Expect = 0.0, Method: Compositional matrix adjust. Identities = 633/2012 (31%), Positives = 1025/2012 (50%), Gaps = 100/2012 (4%) Query: 40 ENRTADDIAIIGIACRFPFADTLEQYWDNLLNGINGITDFPLKRRKDIDPLLQKVME--- 96 EN + DIAIIG++ RF A+ L QYW+ + +G + ITD R+ D K Sbjct: 24 ENISKKDIAIIGMSGRFGAAENLSQYWEYIKDGKDLITDLSGTRQSDCMHFASKFSNKKG 83 Query: 97 TPVYGKGSYLEQVDSFDAEYFRLSPKEAEFMDPHQRLMLEVAAEAIEDAGYMGEKIYGTQ 156 Y KG++ +++D FD ++F +SP+EA MDP+QRL LE EAIEDAGY G++I G++ Sbjct: 84 NTEYLKGAFFKELDKFDNDFFNISPREASLMDPNQRLFLENVWEAIEDAGYCGKRIMGSK 143 Query: 157 TGVFIGRDHHSSGLYQQFIDSSNELA---MTGNLPSFISGRIAFFFNLTGPNQVIDTACS 213 TGV+IG +S LA + GN+ S ++ RIA+ +L GP ++DTACS Sbjct: 144 TGVYIGYSGSKPTYETLLWESEASLAPESLAGNVNSMLASRIAYILDLKGPCMLVDTACS 203 Query: 214 SGLVALHQGCESLRHKECTMAIVGGISLNLLPLANSSFKIV--ENNDGKVRPFDKNATGT 271 S L+A+H C+++R+ EC +A+ GGI LLPL + V ++DGK R FD N+ GT Sbjct: 204 SSLMAVHLACQAIRNGECHIAVAGGIKTLLLPLKTDDSENVGIASSDGKARTFDDNSDGT 263 Query: 272 TWGEGLSAIMIKPLREALKDKDRIYSVVKGSGVNSDGASNYITAPNPEAQERLLIDVWTK 331 GEG++A+++KPL +AL DKD IY+V+KGS N+DG+S ITAPN AQ ++ W Sbjct: 264 GIGEGVAAVLLKPLEQALNDKDHIYAVIKGSAANNDGSSIGITAPNSLAQRDAIVKAWED 323 Query: 332 AGVHPETISYIETHGTGTVIGDPIEVKAMKQAFDQYTNKKQFCGLGSVKSNIGHLVGASG 391 +G++PET+SYIE HGTGT +GDPIE+ +K+AF +YT+KKQFC +GSVKSNIGHL +G Sbjct: 324 SGINPETLSYIEAHGTGTKLGDPIEIDGIKRAFKKYTDKKQFCAIGSVKSNIGHLDNVAG 383 Query: 392 MASLIKVILSMKHRQLVPTIHFEEPNPYIPFSQSPFYMVDKPLAWEAAQGPRRAGISSFG 451 +A LIK +L +++ Q+ PT+HF+ PN I F SP Y+ D+ WE PRR GISSFG Sbjct: 384 IAGLIKAVLCIQYGQIPPTLHFKRPNRKIMFEDSPVYVNDRLHEWETMGYPRRCGISSFG 443 Query: 452 FSGMNCHVLLEEWQQEDQQTVREEPEQP-RIFPVSAKTKSGLLELLQRYSQFLQTHQRAD 510 SG NCH++LEE ++ E P+ ++ +SAK + L LL+ + ++L+ ++ Sbjct: 444 ISGTNCHMILEEAPNSKGKS--ENPQSKLQVLTLSAKNEKSLYSLLKSFDEYLKKNKEVS 501 Query: 511 FQNLVYTAQLGREHFAHRLAIIAKDASELWRKIAAVLLNDVDQLPESIG----YYGYFPI 566 +++ +T GR H + R+A+I ++ ++ KI+ + D P+ I YYGY + Sbjct: 502 IEDICFTQNTGRMHHSLRIALILENRHDMEEKISKL----ADLQPKGIREQGVYYGYHKV 557 Query: 567 RQKAKNNMAQQDLSEAKTRAAYDKARRLVRQIAENPAQAAEGSLEELAQLYVQGTRVDWN 626 + ++ +SE R A ++++ G+LEE+ LY G +DW+ Sbjct: 558 VRNSEGIKNDGYISETDKRELSKTASERLKELV-TSGNYNRGTLEEICILYTTGGDIDWD 616 Query: 627 ALWTGQAVQTARLPVYPFTKTRHW--------PAPAPTEGAFPGVPGPLLGECTVKTAGM 678 L+ + LP YPF + R W + + G +PG + + T Sbjct: 617 FLYKSE--NKVSLPTYPFNRKRFWIDTKRQMKESVQESHGERYKLPGYRISD----TINQ 670 Query: 679 RIYAATLSGKEHWLLQEHRILGNGVWPGVAYLEMAKAASGYFFAGENVVLRQVTLQNMLI 738 +Y A +S + WLL+EH++ GN + G AYLE+A S ++ G+ V +R++TL LI Sbjct: 671 EVYTAEISVENQWLLREHKVGGNYMLVGTAYLELAMQTSKKYYPGKAVEIRELTLLTPLI 730 Query: 739 CPPDETRVVHTIIREEQDHAAFTIASMKEGGHTENWIIHAQGEIYPQAEPKMPVIALEPL 798 ++ +HT+I +E F IAS K WI HAQG IY + E L Sbjct: 731 VGEEDKVELHTVIMKEYGFLKFVIAS-KSKTAENGWIEHAQGRIYGTEKLSDKYDMTEAL 789 Query: 799 IQVMNEESVELFTPILTAGIQYGPSWKCIRRFYQ--NESAAVLHIGSTDGASAREPFSLH 856 + NE +E A ++ G W+C+ + + NE+ L +G E F LH Sbjct: 790 QRCTNEWDIE--NKQKNAVVEVGKRWQCLTKAFSGTNEALGYLELGEEYKGDFDE-FQLH 846 Query: 857 PALMDTALSFWHLLRQREEAADLPAFPFYYESIRIFGVMPASFFSYVRKRETHGDHRETA 916 P ++DTAL+F Q E+A FPF++ S++I + + S+VR + T Sbjct: 847 PPMLDTALNFAG--DQAEKAG--FYFPFHFNSVKIHNPISSKIISHVR---ILNNSDRTI 899 Query: 917 SYDISLIDEAGNVFAEVENYTLKKVSPALISK-DLFYRINWVK---SPRPDGGSRIGG-- 970 Y+I+L+DE V EV+ Y KK + L++K DL + I WV+ + + + G Sbjct: 900 EYNITLVDENRRVLMEVDRYVTKKDAGQLLNKTDLLHSIEWVEYSDTAQDKAFDLLDGNK 959 Query: 971 TVLLFGNDCRATREFIRHMEAGDVELIQVVQGEAYRKEKDSRYVVGNAAADYIQLFADLQ 1030 + L F + R+ E I +EA +++I+V GE Y +Y VG + D+ QLF+ Sbjct: 960 STLFFSDKSRSCNEIINRLEAKGIKVIEVNTGEEYGVLGKDKYSVGYSQEDFYQLFSQES 1019 Query: 1031 GRNVSRMIHGYALDEDSGADSLSSLQAVQ---EKSVQSLFFIIKALVQAKYKEQIELVLL 1087 ++++ +++ DSG S ++ ++ E SV +LF + KA +Q + I++V+L Sbjct: 1020 IKDINYIVYS----PDSGLPDTSDIKILENKLENSVYNLFRLTKAWMQKNTGKDIKIVIL 1075 Query: 1088 GKQGYEVTGGEKELEPCYAAFYNLGKVADTEYPNLKCRSIDLGDETEWGAVLEEIFGERT 1147 VTG E+ L P AA + + V EYPNLK + ID+ + E +++ E Sbjct: 1076 STYVNSVTGNEECLNPENAALFGMAFVLKKEYPNLKIKCIDMDEGCEAESIISEFQTVHK 1135 Query: 1148 ANQVAYRENKRFIXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXXXELARYXXXXXXX 1206 +A+R +R+I E+A++ Sbjct: 1136 TRMIAFRNGRRYIEQLKRVKREQNPSNSVKIRENGVYIITGGLGGIGLEIAKHMASGTNL 1195 Query: 1207 XXXXXXXXXXPPREAWEDIRQSGTEPGTSRKIELLEEIERSGSQVMICPCDISDGQQLKH 1266 P R W+ I ++ + KI+ + +IE GS+V D+SD Q +K Sbjct: 1196 NVIMINRSEMPERSQWDTILETEKDLKLCNKIKSIMDIESLGSKVTYYNGDVSDMQSMKL 1255 Query: 1267 CLMQLREAYGPVKXXXXXXXXXXSGYLFTKDWSDFTRVTAPKIEGTYLLYSLLQE-QPDF 1325 + + + YG + +G TKD V A K++GT+++ SL DF Sbjct: 1256 IIEDVIKNYGKINGIIHSAGIAGNGLAITKDEKRIKEVMAAKVKGTWIIDSLTSNLNMDF 1315 Query: 1326 FVLFSSIATLEGSPGQGDYAAGNGYLDGFAHFLRRKGVRGLTLNWAAWEETGMALDNGAL 1385 +LFSS TL S GQ DY A N Y+D + ++ ++ +NWAAW+ETGMA ++ A Sbjct: 1316 LLLFSSAETLTTSAGQSDYTAANYYMDTYCYYRNKRNQPTFCINWAAWKETGMAKEHNAD 1375 Query: 1386 GSKIYRPLKTGTAVHAFSRALQLEEPRVIIADIRLDQLDESVTGKLPLQLSPDLRRTGNR 1445 ++ L T V F L+ +PRVI + + L + LP+ L P+L +R Sbjct: 1376 RDGVFMVLSTANGVRVFDEVLKSGQPRVIAGQLNYNLL-AGLKESLPVTLEPELSAVLDR 1434 Query: 1446 FAQPRPVAAAADT-------IAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYEL 1498 + R A T I + G + I++ EQA+ +WA F ++++ +FY+ Sbjct: 1435 SKKTRKSDIIAGTTKQDTVDIKLTGKTDDQITKTEQAIGYIWASIFQSNEINVYDSFYDQ 1494 Query: 1499 GGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSGLAAYLEQSLPSRNEATAKA--AGSE 1556 GGDSI A ++ N++ +SI ++ ++ L Y++ +A+ K+ G Sbjct: 1495 GGDSIFAMKITNVIRNTWGINISITDVMNNQSIYELGKYIDSEFAETKQASLKSLPIGKA 1554 Query: 1557 APNAGYDLSKAQHRIWFLQNYDPQTTAYHLPVVKQIREAIDLAVLQQGLDILTRRHSSLR 1616 + Y +S +Q R++ L+ Y T Y++PV + +++ ++ + + +RH SLR Sbjct: 1555 EKSDYYPVSSSQKRLYILEQYGNIGTTYNIPVALMVEGRLNIQRVENSIGRIIQRHESLR 1614 Query: 1617 TIIKNVNGIPKQFVVPDKSHVIHFTDYAQEPHXXXXXXXXXXXXNTTAFELEQNLFRAEL 1676 T K VNG Q V D + + A E N L + L L Sbjct: 1615 TTFKEVNGSISQIVHKDYKPDFRYFE-ADEKKTETIIRDFVKPFNLNKGPLVKTL----L 1669 Query: 1677 HRYEESDYLLYINMHHIISDGWSMGVFFREWMELYDQIRSKRPIQLAPIALQPVDWVEQE 1736 ++ YLL ++ HHI++D S + +E++++Y + +L Q D+ + Sbjct: 1670 VKFSSDRYLLLMDFHHIVTDWASSDIIIKEFIDIY------KDNELPEPGTQYKDYSVWQ 1723 Query: 1737 KLWIGSGDYLNMERYWMKELAQPLPVLELPTDYDRPHSIA---YDGSYIKFTVSEEVTGQ 1793 S ++L E YW+ + +PVL LP D + H + Y G I F + ++T + Sbjct: 1724 NQLFSSKEFLEQENYWLNIFSGDIPVLHLPVD-KKEHDESVPDYTGKSISFKLGADLTER 1782 Query: 1794 LRLLAKNRSSTLYMTVLAIYFLFLKKLSQEEDIIVGFPVSGREQQEWENIIGLFMNMVCI 1853 L ++ + TL+M +LA Y + L K + +EDI++G P+SGR + EN +G+F+NM+ + Sbjct: 1783 LDKFSQKQGVTLFMLLLASYNILLSKYTGQEDIVIGSPISGRIHTDVENTVGMFVNMLPM 1842 Query: 1854 RVDFRELSSFGGVLEEVKRKCLKAYANGRYPFNTLVEKLNPERDPSRTPVFSTIFQLY-- 1911 R +F G LEEV+ C A+ N YPF ++ +L +++ +FS F L Sbjct: 1843 RNFPSGNKTFAGFLEEVRDNCFGAFENQDYPFEMMISRLEAQKNTKINSLFSITFALMTR 1902 Query: 1912 --DNVPQDNDRM---------SLYDLSCICKMDGGQIEVRLEYKTSLFTEETIQNYACYL 1960 + + D+ +M S +DL+ G I + Y+T+LF +++ N+ Y Sbjct: 1903 REERIDVDDFKMMPVNIPVTTSKFDLTIDAVKVDGDIAIDFRYRTALFRSDSMDNFIKYY 1962 Query: 1961 THLINQVIADPEGQLSRYELLDARHKAEIINQ 1992 L+ VI +PE ++ + L+ R +NQ Sbjct: 1963 KELLEIVIEEPEIKIEDIDFLEEREDGTSLNQ 1994 >C3HA42.1 C3HA42_BACTU Beta-ketoacyl synthase Length = 1604 Score = 1023 bits (2644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 563/1600 (35%), Positives = 881/1600 (55%), Gaps = 72/1600 (4%) Query: 11 ILESVKANRLDQKLALKILHQLNSGPAEAENRTADDIAIIGIACRFPFADTLEQYWDNLL 70 ILE VK ++ Q+ A K+L +LNS E+ ++DIA+IGI+C+ P A+ E+YW+NL+ Sbjct: 8 ILEQVKQRKITQEQAKKMLQELNS-----ESMQSEDIAVIGISCKLPKANNTEEYWNNLI 62 Query: 71 NGINGITDFPLKRRKDIDPLLQKVMETPVYGKG-------------SYLEQVDSFDAEYF 117 N ++ ++ + K I P++ T G G YLE VD FDAE+F Sbjct: 63 NSLDCKVNYQEEMIKYIKPIVNNKGFTDFLGSGFLTEEQADDWKLGGYLEDVDKFDAEFF 122 Query: 118 RLSPKEAEFMDPHQRLMLEVAAEAIEDAGYMGEKIYGTQTGVFIGRDHHSSGLYQQFIDS 177 +SPKEA+ +DP R++LE AIEDAGY G+KIYG+ T +F+G+DH ++ LY+ +I Sbjct: 123 NISPKEAKAIDPSHRVLLETVWTAIEDAGYGGDKIYGSNTSLFVGKDHVNNTLYR-YITE 181 Query: 178 SNELAMTGNLPSFISGRIAFFFNLTGPNQVIDTACSSGLVALHQGCESLRHKECTMAIVG 237 S +MTGN P ++GRI + NL G + V+D+ACSSGL+ +H C +L+ KEC MAIV Sbjct: 182 SESSSMTGNWPGLMAGRINYLLNLKGNSMVLDSACSSGLLGVHLACNALKSKECEMAIVS 241 Query: 238 GISLNLLPLANSSFK-IVENNDGKVRPFDKNATGTTWGEGLSAIMIKPLREALKDKDRIY 296 GISL P +S K ++E+ KV FDKNA GT + +G++A+++KPL +A +D D IY Sbjct: 242 GISLGFFPRFETSRKSMMESKSDKVNAFDKNADGTFFSDGVAAVILKPLNKARRDGDNIY 301 Query: 297 SVVKGSGVNSDGASNYITAPNPEAQERLLIDVWTKAGVHPETISYIETHGTGTVIGDPIE 356 +V+KGS +N+DGASN +TAPN AQE +LI W A V+PETI YIE HGTGT +GDPIE Sbjct: 302 AVIKGSAINNDGASNGLTAPNAIAQEEVLIKAWENAQVNPETIQYIEAHGTGTKLGDPIE 361 Query: 357 VKAMKQAFDQYTNKKQFCGLGSVKSNIGHLVGASGMASLIKVILSMKHRQLVPTIHFEEP 416 +K + AF +YT+K QFCG+GSVKSNIGH V SG+ASLIK++LSMKH + P+I+F+EP Sbjct: 362 IKGITNAFSKYTDKIQFCGVGSVKSNIGHTVAVSGLASLIKIVLSMKHNIIPPSINFKEP 421 Query: 417 NPYIPFSQSPFYMVDKPLAWEAAQGPRRAGISSFGFSGMNCHVLLEE--WQQEDQQTVRE 474 N I F SP ++ DKP W PRRAGISSFGF G N H+++EE Q D+ + + Sbjct: 422 NSLINFVNSPVFVTDKPHKWPRGIVPRRAGISSFGFVGTNAHIVVEEPSIQSNDELSSKL 481 Query: 475 EPEQPRIFPVSAKTKSGLLELLQRYSQFLQTHQRADFQNLVYTAQLGREHFAHRLAIIAK 534 E +F +SAKT+ L++LL++Y++F + + +N+ YT GR H+ +RLAII K Sbjct: 482 TFE---VFTLSAKTEKSLIQLLKKYNEFFKKGTQKSLKNICYTVNTGRGHYGYRLAIIVK 538 Query: 535 DASELWRKIAAVLLNDVDQLPESIGYYGYFPIRQKAKNNMAQQDLSEAKTRAAYDKARRL 594 EL +KI + +++ + E Y+GY I K M + +++ ++ R K L Sbjct: 539 SYEELIQKIDLLCNQNLNDISEKGVYFGYHKIGSDRKKVMDEGEITLSEHRKMNTKVENL 598 Query: 595 VRQIAENPAQAAEGSLEELAQLYVQGTRVDWNALWTGQAVQTARLPVYPFTKTRHWPAPA 654 + I+ + +L E+ LY++G +V+W ++ + LP Y F + + W Sbjct: 599 LLDISNESNEYLVLNLTEICDLYIKGAKVNWKKIYVDEKRNIVSLPTYQFERIQCWGEVK 658 Query: 655 PTEGAFP---GVPGPLLGECTVKTAGMRIYAATLSGKEHWLLQEHRILGNGVWPGVAYLE 711 P + PL+ +C + IY+ T + + W+L +H+I+G V PG YLE Sbjct: 659 DRRDETPIQKNISHPLIDQCLADSMNETIYSTTFNVDKDWVLSDHKIMGVSVIPGTTYLE 718 Query: 712 MAKAASGYFFAGENVVLRQVTLQNMLICPPDETRVVHTIIREEQDHAAFTIASMKEGGHT 771 M + AS FF N+ LR V L+ DE +VVHTII++E++ FTIAS KEG Sbjct: 719 MGRKASSEFFGNNNLELRDVIFFTPLLVHQDENKVVHTIIKKEKEGVRFTIAS-KEG--- 774 Query: 772 ENWIIHAQGEIYPQAEPKMPVIALEPLIQVMNEESVEL----FTPILTAGIQYGPSWKCI 827 E WI HA+G Y E K + L + + N E +++ T + + +GP W Sbjct: 775 EKWIPHAEGRAYELKEMKSIMFDLSLMKKDANREKIKVEYEDDTQLTSNVFTFGPRWLNF 834 Query: 828 RRFYQNESAAVLHIGSTDGASAR-EPFSLHPALMDTALSFWHLLRQREEAADLPAFPFYY 886 + + ++ + +D + LHP+L+D A + + E+ D P Y Sbjct: 835 KEVILDHDEQLVELKLSDEFKGDLKDLLLHPSLLDNAANVF----IGEDDDDSTFLPLSY 890 Query: 887 ESIRIFGVMPASFFSYVRKRETHGDHRETASYDISLIDEAGNVFAEVENYTLKKVS--PA 944 +S++I+ VMP F+++V K+ + ++ET +I LID AG VFAE+ +Y LKK Sbjct: 891 KSVKIYSVMPQHFYAHVIKKSS---NKETKVCNIQLIDTAGVVFAEITDYVLKKADRLDT 947 Query: 945 LISKDL-----FYRINWVKSPRP-DGGSRIGGTVLLFGNDCRATREFIRHMEAGDVELIQ 998 + ++L FY I WV+ +P + T+L+F + ++ I+ ++ + +IQ Sbjct: 948 IFDENLEKESSFYHIKWVQGSKPVKVNTNTSETILVFKDKQEIYKKVIKELQYDNHNIIQ 1007 Query: 999 VVQGEAYRKEKDSRYVVGNAAADYIQLFADLQGRNVSRMIHGYALDEDSGADSLSSLQAV 1058 V G + K D ++++ A DY L +++ RN++++IH ++ + A S+L+ + Sbjct: 1008 VEFGNRFEKINDQQFIINGMADDYSNLINEVKERNITKIIHLSSM-TNGEAIHFSNLKEL 1066 Query: 1059 QEKSVQSLFFIIKALVQAKYKEQIELVLLGKQGYEVTGGEKELEPCYAAFYNLGKVADTE 1118 Q + SLF++++ + K K I+L+L+ EVTG EK + P AA + LG V E Sbjct: 1067 QHNGLYSLFYLVRGISVNKVKRNIDLILISNNVTEVTGNEKTINPLGAAMFGLGSVISQE 1126 Query: 1119 YPNLKCRSIDLGDETEWGAVLEEIFGERTANQVAYRENKRFIXXXXXXXXX--XXXXXXX 1176 + N+KCR+ID+ D T +++EEI E Q+A+R N R+I Sbjct: 1127 FSNIKCRAIDVDDHTAITSIIEEIKSEDKHYQIAFRNNIRYISELDVVEHNPDKQGAGLE 1186 Query: 1177 XXXXXXXXXXXXXXXXXXELARYXXXXXXXXXXXXXXXXXPPREAWEDIRQSGTEPGTSR 1236 E+A+Y P E WEDI G++ SR Sbjct: 1187 IKENGVYMITGGTGGIGLEIAKYLAGKNKVNIVLLNRSKLPEMELWEDIINDGSDQKLSR 1246 Query: 1237 KIELLEEIERSGSQVMICPCDISDGQQLKHCLMQLREAYGPVKXXXXXXXXXXSGYLFTK 1296 K+E++ I+ GS+V C++SD + + +++E YG + G++F K Sbjct: 1247 KLEIIRSIQGMGSEVKCYSCEVSDFSSMSKVIGEVKEKYGKINGIFHCAGVAGEGFIFRK 1306 Query: 1297 DWSDFTRVTAPKIEGTYLL-YSLLQEQPDFFVLFSSIATLEGSPGQGDYAAGNGYLDGFA 1355 + F V PKI GT+L+ Y E DF +LFSSI ++ G GQGDY A N YLD F+ Sbjct: 1307 QEAVFKEVINPKISGTWLIDYLTKDENIDFSILFSSINSIFGGAGQGDYTAANAYLDSFS 1366 Query: 1356 HFLRRKGVRGLTLNWAAWEETGMALDNGALGS-KIYRPLKTGTAVHAFSRALQLEEPRVI 1414 ++ +KG + +++NW AW+E G+A+D G I++ L A+ + VI Sbjct: 1367 YYRNKKGKKTISINWPAWDEVGIAVDYGVTDEFSIFKLLTVNKALSILDTIVDNALTNVI 1426 Query: 1415 IADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPRPVAAAADTIA--------IIGHSG 1466 + +D L E G+LP +LS ++ N+ + + + ++ +I G Sbjct: 1427 PGKLNMDIL-EVAKGELPFELSISIK---NKLKEAKKTRVETEKVSLKNSTSDVVIKGKG 1482 Query: 1467 AVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIF 1526 SE E+ +AQ+++ + ++D+ ++F +GGDSIMATQ+ L+N + + I++IF Sbjct: 1483 EYYSETEKNIAQMYSMVLDIPELDLYESFSAMGGDSIMATQLLKLINQKYPNLVDISDIF 1542 Query: 1527 EYPTVSGLAAYLEQSLPSRNEATAKAAGSEAPNAGYDLSK 1566 YP+V L+ Y++ + NE G N +L K Sbjct: 1543 TYPSVVELSEYIDGEI---NENDHLKNGETNVNNDNNLEK 1579 >B8I5H4.1 B8I5H4_CLOCE Beta-ketoacyl synthase Length = 1613 Score = 913 bits (2360), Expect = 0.0, Method: Compositional matrix adjust. Identities = 526/1591 (33%), Positives = 854/1591 (53%), Gaps = 100/1591 (6%) Query: 11 ILESVKANRLDQKLALKILHQLNSGPAEAENRTADDIAIIGIACRFPFADTLEQYWDNLL 70 I+E+ + +K A +I+ L + E R+ +DIAI+G+A + PFA ++++W N+ Sbjct: 8 IVENTGNGNISKKAAAQIIRLLK----DDEIRSDNDIAIVGMAAKLPFAPNIDEFWINIR 63 Query: 71 NGINGITDFPLKRRKDIDPLLQKVMETPV---YGKGSYLEQVDSFDAEYFRLSPKEAEFM 127 NG + ++DFP +R+KD D LL + P Y G++L++VD FD ++F+LSPKEA + Sbjct: 64 NGRDCVSDFPEERKKDTDALLGHMNLKPSEIEYSIGAFLDEVDKFDYKFFKLSPKEASLI 123 Query: 128 DPHQRLMLEVAAEAIEDAGYMGEKIYGTQTGVFIGRDHHSSGLYQQFIDSSNE----LAM 183 DP+QRL L+ A +AIED+GY ++ G++TGV++G Y++FI + + +A+ Sbjct: 124 DPNQRLFLQTAYQAIEDSGYGNGRLSGSKTGVYVGYSSDFGESYKRFIHTVDPGLSGIAI 183 Query: 184 TGNLPSFISGRIAFFFNLTGPNQVIDTACSSGLVALHQGCESLRHKECTMAIVGGISLNL 243 GN+ S I+ RI+++ +L GP+ ++DTACSS LVA+H C ++R+ EC A+ GG+ LNL Sbjct: 184 PGNIKSIIASRISYYLDLKGPSMLVDTACSSSLVAIHMACRAIRNGECETALAGGVKLNL 243 Query: 244 LPLA-NSSFKI-VENNDGKVRPFDKNATGTTWGEGLSAIMIKPLREALKDKDRIYSVVKG 301 LPL N I + ++DGK R FD ++ GT GEG +AI++KPL++A+ D+D +Y+V+KG Sbjct: 244 LPLKINRQDGIGITSSDGKARSFDDSSDGTGIGEGCAAILLKPLKKAIADRDNVYAVIKG 303 Query: 302 SGVNSDGASNYITAPNPEAQERLLIDVWTKAGVHPETISYIETHGTGTVIGDPIEVKAMK 361 S +N DG S ITAPN AQE +++ W AGV+PETISYIE HGTGT +GDP+E+ ++ Sbjct: 304 SAINQDGNSIGITAPNSAAQEEVIVKAWKDAGVNPETISYIEAHGTGTKLGDPLEIDGIE 363 Query: 362 QAFDQYTNKKQFCGLGSVKSNIGHLVGASGMASLIKVILSMKHRQLVPTIHFEEPNPYIP 421 AF +YT+KKQFC LG+VK+NIGHL ASGMA +IK+++++ +++L P +HF+ PN Sbjct: 364 SAFKRYTDKKQFCALGTVKTNIGHLDNASGMAGVIKMVMALTNKELPPMLHFKRPNRKTN 423 Query: 422 FSQSPFYMVDKPLAWEAAQGPRRAGISSFGFSGMNCHVLLEEW-QQEDQQTVREE---PE 477 +SP Y+ D+ WE PRR GISSFG SG NCH++LEE E Q EE P Sbjct: 424 IQESPVYINDRLTQWETDGFPRRCGISSFGLSGTNCHMILEEAPSSEKPQYPAEESIIPY 483 Query: 478 QPRIFPVSAKTKSGLLELLQRYSQFLQTHQRADFQNLVYTAQLGREHFAHRLAIIAKDAS 537 + + +SA S L ++ Y L + +++ YTA GR HF R+AII D Sbjct: 484 RKNVLTISANHVSALQSYIEAYRHMLDNIKNVTLEDICYTANTGRTHFPVRIAIITTDIK 543 Query: 538 ELWRKIA----AVLLN-DVDQLPESIGYYGYFPIRQKAKNNMAQQDLSEAKTRAAYDKAR 592 +L +K+A ++ N D + + Y P +N + D T A+ D Sbjct: 544 DLKQKLAFLTGSIKYNIDTKCIYSAKEYATDHPGISTFENLTPEADTLPDLTSASGDIYN 603 Query: 593 RLVRQIAENPAQAAEGSLEELAQLYVQGTRVDWNALWTGQAVQTARLPVYPFTKTRHW-P 651 + L+E+ + Y+ G + W+ ++ G+ ++ LP YPF + R W Sbjct: 604 K---------------HLDEICKSYISGDHIQWDKVYDGKGMKKVSLPTYPFERLRCWLT 648 Query: 652 APAPT-------EGAFPGVPGPLLGECTVKTAGMRIYAATLSGKEHWLLQEHRILGNGVW 704 A P E ++ + PLL C+ +T +Y+ HW+L EH++ GN + Sbjct: 649 ANTPKAAEINAYEQSYNKLGYPLLDSCSTETMEGAVYSTNFQVNRHWVLNEHKVNGNFIV 708 Query: 705 PGVAYLEMAKAASGYFFAGENVVLRQVTLQNMLICPPDETRVVHTIIREEQDHAAFTIAS 764 PG +Y+EM A G++ EN+ R + + L +E R V T+++ E + F +AS Sbjct: 709 PGTSYIEMVSEAVGHYKYYENLEFRDIIFEFPLAVGENEARDVQTVLKIEDGYLGFYVAS 768 Query: 765 MKEGGHTENWIIHAQGEIYPQAEPKMPVIALEPLIQ-VMNEESVELFTPILTAGIQYGPS 823 +G + W+ H QG+++ + + + + + EE +EL T I GP Sbjct: 769 RPDG---DKWVRHVQGKVFLDEDRNSVQYNPDEMARSAIFEEDIEL-TGKRKGLIDTGPR 824 Query: 824 WKCIRRFYQNESAAVLHIGSTDGASAR-EPFSLHPALMDTALSFWHLLRQREEAADLPAF 882 W +++ Y + ++ D + + +HPALMD+A++ + Sbjct: 825 WNNLKKVYTLHDGVLAYLVLPDEFTGDLDKCIIHPALMDSAVNV-----AIGSIGEGLYL 879 Query: 883 PFYYESIRIFGVMPASFFSYVRKRETHGDHRETASYDISLIDEAGNVFAEVENYTLKKVS 942 P+ Y+S+ I+G MP +S +R++ + ETAS+DI L+DE G VFA++ENYTLKKV+ Sbjct: 880 PWSYKSLIIYGKMPDKLYSLIRQKGKADLNMETASFDIILMDEKGRVFADIENYTLKKVN 939 Query: 943 PALISKD-------LFYRINWVKSPRPDGGSRI-------GGTVLLFGNDCRATREFIRH 988 L + D +F+R+NW+K+ G I G VLLF + R + ++ Sbjct: 940 QLLTTPDYKSVKVNMFHRMNWIKNYTTKGVESIHNAYKPAAGKVLLFKD--RGSL-WMDI 996 Query: 989 MEAGDVELIQVVQGEAYRKEKDSRYVVGNAAADYIQLFADLQGRNVSRMIHGYALDEDSG 1048 E V++++V Y K RY +G DY +L DL+ +S++IH ++ + Sbjct: 997 KETLGVDVVEVDICGCYEKFATGRYSIGYGEEDYDRLIKDLREEGISQIIHLSSIGWEKL 1056 Query: 1049 ADSLSSLQAVQEKSVQSLFFIIKALVQAKYKEQIELVLLGKQGYEVTGGEKELEPCYAAF 1108 + SL Q++ + SL ++I++L+ K + ++EL+ + VTG E+ + A Sbjct: 1057 PEDSDSLAETQKRGLYSLVYLIRSLISNKIRNEVELIAVSDYVNMVTGMERRINYYNATI 1116 Query: 1109 YNLGKVADTEYPNLKCRSIDLGDETEWGAVLEEIFGERTANQVAYRENKRFIXXXXXXXX 1168 + VA EY NLKCR ID+ + TE ++ E+ + + +AYR+ +R+ Sbjct: 1117 PGICTVAGQEYGNLKCRCIDIDETTEVNKLVSELNSRDSCSLIAYRDGERYHQEMDEVHL 1176 Query: 1169 XXXX-XXXXXXXXXXXXXXXXXXXXXXELARYXXXXXXXXXXXXXXXXXPPREAWEDIRQ 1227 E A Y P REAW++I + Sbjct: 1177 EDSEPEEIEICEKGVYIITGGLGGIGREFAGYLSAKKPVSLVLIARTYIPDREAWDEILK 1236 Query: 1228 SGTEPGTSRKIELLEEIERSGSQVMICPCDISDGQQLKHCLMQLREAYGPVKXXXXXXXX 1287 + ++KIE +++IE+SGSQV+ D+S+ +K+ L +R YG + Sbjct: 1237 KNSGTMLAQKIEFIKDIEKSGSQVVYYSADVSNENDMKNVLSSIRRKYGRINGVIHAAGI 1296 Query: 1288 XXSGYLFTKDWSDFTRVTAPKIEGTYLLYSLLQEQP-DFFVLFSSIATLEGSPGQGDYAA 1346 +G++ KD FTRV PK++GT++L L +E DFF++FSSI ++ G GQ DY A Sbjct: 1297 AGNGFIIRKDMEIFTRVVKPKVQGTFILDKLTKEDNLDFFIMFSSINSILGGAGQSDYTA 1356 Query: 1347 GNGYLDGFAHFLRRK-GVRGLTLNWAAWEETGMALDNGALGSKI---YRPLKTGTAVHAF 1402 N ++D FA + R+ G + +++NW AW+ETGMA DNG + KI + P T A+ F Sbjct: 1357 ANSFMDSFADYRRKTAGGKTVSINWTAWKETGMAFDNGIINGKIRGVFLPATTSDAIQMF 1416 Query: 1403 SRALQLEEPRVIIADIRLD-----------QLDESVTGKL---PLQLSPDLRRTGNRFAQ 1448 + R+I + + + + GK+ ++ + D +R R + Sbjct: 1417 EEITAKKLTRIIAGQLDFETIPLLDSGTAIRFSNKIQGKIHKYKVRSNTDSQRNTAREGE 1476 Query: 1449 PRPVAAAADTIAIIGHSGAVISEMEQAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQM 1508 P + I G IS ++ VA++WA GL+++ + NF +LGGDS+MAT + Sbjct: 1477 ITP-------LKIKGSKDKGISSVQAVVARIWAGALGLEEVSVYDNFNDLGGDSVMATLL 1529 Query: 1509 ANLLNTQLHQKLSIAEIFEYPTVSGLAAYLE 1539 L + + I++IF YP++S ++ Y+E Sbjct: 1530 LKNLEKEFPGIVDISDIFNYPSISAMSEYIE 1560 >C3HA41.1 C3HA41_BACTU Beta-ketoacyl synthase Length = 1609 Score = 815 bits (2104), Expect = 0.0, Method: Compositional matrix adjust. Identities = 490/1576 (31%), Positives = 808/1576 (51%), Gaps = 110/1576 (6%) Query: 41 NRTADDIAIIGIACRFPFADTLEQYWDNLLNGINGITDFPLKRRKDIDPLLQ----KVME 96 N + DIAIIGI+ +F A+ L YWD L+N I D P+ R+KD D L+ K Sbjct: 36 NISETDIAIIGISGKFGKANNLNDYWDLLINEEELIRDIPINRKKDADNYLEYSGIKNKN 95 Query: 97 TPV-YGKGSYLEQVDSFDAEYFRLSPKEAEFMDPHQRLMLEVAAEAIEDAGYMGEKIYGT 155 V Y K +YL++++ FD ++F + P EA+ +DP QRL +E A A+EDAGY G K+ GT Sbjct: 96 KDVNYTKIAYLDEINKFDCDFFEIIPNEAKLIDPRQRLFVETAWNALEDAGYGGGKLCGT 155 Query: 156 QTGVFIGRDHHSSGLYQQFIDSSNE----LAMTGNLPSFISGRIAFFFNLTGPNQVIDTA 211 +TG+++G S Y + I+ ++ LA GN+ S I+ R+A+ + GP VIDTA Sbjct: 156 KTGIYVGLSSDGSNEYFKLIEKGDQSLLGLATAGNIKSVIASRLAYILDFKGPTMVIDTA 215 Query: 212 CSSGLVALHQGCESLRHKECTMAIVGGISLNLLPLANSSFKI---VENNDGKVRPFDKNA 268 CSS LV LH C++LR+++C A+VGG+++ + P K + ++D V+ FD A Sbjct: 216 CSSSLVTLHTACQALRNRDCDTALVGGVNIKVFPKTEEENKWNIGITSSDSIVKTFDNEA 275 Query: 269 TGTTWGEGLSAIMIKPLREALKDKDRIYSVVKGSGVNSDGASNYITAPNPEAQERLLIDV 328 GT GEG++AI++KPL+ A+ DKD+IY+V+KGS +N DG+S ITAPN AQE +++D Sbjct: 276 DGTNSGEGVAAILLKPLKNAILDKDQIYAVIKGSAINQDGSSVGITAPNVTAQENVILDA 335 Query: 329 WTKAGVHPETISYIETHGTGTVIGDPIEVKAMKQAFDQYTNKKQFCGLGSVKSNIGHLVG 388 W A + P+TI+YIE HGTGT +GDPIEV A++QAF ++T++KQFC + SVK+NIGHL Sbjct: 336 WKDAHIDPKTITYIEAHGTGTKLGDPIEVSAIQQAFSKFTDRKQFCAISSVKTNIGHLDS 395 Query: 389 ASGMASLIKVILSMKHRQLVPTIHFEEPNPYIPFSQSPFYMVDKPLAWEAAQGPRRAGIS 448 +G+A LIK ++++KH+++ P+++F+ PN I F +SP Y+ D+ W G R G+S Sbjct: 396 LAGLAGLIKAVMALKHKKIPPSLNFKVPNRNINFHESPVYVNDRVQDWINNDGVYRCGVS 455 Query: 449 SFGFSGMNCHVLLEEWQQEDQQTVREEPEQPRIFPVSAKTKSGLLELLQRYSQFLQTHQR 508 SFG SG NCHV+LEE + +Q E IF VSA+TK L LL RY +FL + Sbjct: 456 SFGLSGTNCHVILEEAPKIEQH--EETVFSENIFTVSARTKKSLFNLLNRYVEFLGKEKE 513 Query: 509 ADFQNLVYTAQLGREHFAHRLAIIAKDASELWRKIAAVLLNDVDQLPESIGYYGYFPIRQ 568 ++ YT GR RLA+I K EL K+ ++ ++ P+ YF + + Sbjct: 514 VKLHDICYTVNTGRLANKFRLALIIKTKEELLEKLELLVRSEWKTYPDK---DIYFQMIE 570 Query: 569 KAKNNMAQQ----DLSEAKTRAAYDKARRLVRQIAENPAQAAEGSLEELAQLYVQGTRVD 624 K + + ++E+ T + +R++ +I ++ + L+ L+++Y G V+ Sbjct: 571 KNTRFIGRSIFFTRINESHTSH---QIKRIINRIRKDITHINKCDLQFLSEVYCNGADVN 627 Query: 625 WNALWTGQAVQTARLPVYPFTKTRHWPAPAPTEGAFPGVPG--PLLGECTVKTAGMRIYA 682 + L+ Q LP Y F R W + PL+ +++ M +Y Sbjct: 628 FEELYRQFNFQKVSLPTYSFDGKRLWIDLKEKSNSISSEKDKHPLINNLVLQSFNMEVYV 687 Query: 683 ATLSGKEHWLLQEHRILGNGVWPGVAYLEMAKAASGYFFAGE-NVVLRQVTLQNMLICPP 741 + L+ K+HW+L EH++ + V PG Y++ A+ +F N+VL+ V ++L Sbjct: 688 SHLNVKDHWILNEHKVENSYVVPGTTYIDTAREIGKRYFGDSWNIVLKNVMFPHLLQVKD 747 Query: 742 DETRVVHTIIREEQDHAAFTIASMKEGGHTENWIIHAQGEIYPQAEPKMPVIALEPL--- 798 ETR VHTII ++D F++ S + G E W+ HA+ I + + + +E L Sbjct: 748 VETREVHTIINIKEDALEFSVVS--KLGEVE-WVKHAEALIVKEVKERPKKYDIEVLKKN 804 Query: 799 ------IQVMNEESVELF------------TPILTAGIQYGPSWKCIRRFYQNESAAVLH 840 IQ N V++ T + + G WKC Y+N + Sbjct: 805 YESVYIIQKNNRSLVDVNQKDYESVYFIEDTNRSESIVSVGDRWKCTNAIYRNSEGVLCE 864 Query: 841 IG-STDGASAREPFSLHPALMDTALSFWHLLRQREEAADLPAFPFYYESIRIFGVMPASF 899 + + + + +SLHPA+MD A++ D P+YY++ RIFG P F Sbjct: 865 LEIKKEYQNDFDCYSLHPAMMDCAVNAATFT-----INDESYLPYYYKNFRIFGSTPKKF 919 Query: 900 FSYVRKRETHGDHRETASYDISLIDEAGNVFAEVENYTLKKVSPAL----ISKDLFYRIN 955 +SY+ K+ D+ ET +DI L++EAG VF E+ NY +KKV + SK +++++ Sbjct: 920 YSYITKKT--NDNEETGKFDILLLNEAGEVFGEISNYIVKKVHGSTEKIDKSKQMYHKLA 977 Query: 956 WVKSPRPDGGSRIGG-TVLLFGNDCRATREFIRHMEAGDVELIQVVQGEAYRKEKDSRYV 1014 WV + +LLF N+ + + + + +I+V G+ + K + +Y Sbjct: 978 WVSKKDYILERKYDNRNILLFKNEGELSNKIAKQLRVDGKSVIEVELGKQFSKISNWKYT 1037 Query: 1015 VGNAAADYIQLFADLQGRNVSRMIHGYALDEDSGADSLSSLQAVQEKSVQSLFFIIKALV 1074 + DY +LF ++ N++++IH ++ ++ + L LQ ++SLF++ K+++ Sbjct: 1038 IRGEQEDYDKLFEAIENENINQIIHLMTINNETD-EELLQLQKKLSIGLESLFYLTKSIM 1096 Query: 1075 QAKYKEQIELVLLGKQGYEVTGGEKELEPCYAAFYNLGKVADTEYPNLKCRSIDLGDETE 1134 + K +EL+L + V G E +++P AAF+ GKV + EYP L R ID+ D+ Sbjct: 1097 K-NTKNSMELLLFTDFAHRVNGEEFKIKPHNAAFFGFGKVIEKEYPKLSVRCIDIDDKIC 1155 Query: 1135 WGAVLEEIFGERTANQVAYRENKRFIXXXXXXXXXXX-XXXXXXXXXXXXXXXXXXXXXX 1193 + EI ++ VAYR+ +++ Sbjct: 1156 VEDCITEINSKKQVELVAYRDKDKYVQELQNVDIKALPEEKVEFKKDGVYVITGGMGGIG 1215 Query: 1194 XELARYXXXXXXXXXXXXXXXXXPPREAWEDIRQSGTEPGTSRK------IELLEEIERS 1247 E+A+Y I +SG S K I+ + EI+ S Sbjct: 1216 LEMAKYISSKENVNLIL--------------IGRSGLSATASEKSKIAYKIKTINEIQES 1261 Query: 1248 GSQVMICPCDISDGQQLKHCLMQLREAYGPVKXXXXXXXXXXSGYLFTKDWSDFTRVTAP 1307 GS+V ++++ ++K ++R+ + + G++F K+ F V P Sbjct: 1262 GSRVECYKANVANEHEIKEVFREIRKKFNKIDGVIHGAGVSGEGFIFRKEKEVFDNVIKP 1321 Query: 1308 KIEGTYLLYSLLQ-EQPDFFVLFSSIATLEGSPGQGDYAAGNGYLDGFAHF--LRRKGVR 1364 KI GT+++ L + +Q DFF++FSSI +L GS GQ DYAA N Y+D F F L + Sbjct: 1322 KIHGTWIMNQLTKDDQLDFFIMFSSITSLGGSMGQADYAAANAYMDSFEEFRSLVVPEQK 1381 Query: 1365 GLTLNWAAWEETGMAL-----------DNGALGSKIYRPLKTGTAVHAFSRALQLEEPRV 1413 LT+NW W + GM DN ++ + + A++ F +Q E +V Sbjct: 1382 TLTINWCGWNDVGMLAEYIDKRKEEHKDNNG-----FKTINSIEAIYTFDEIIQKEISKV 1436 Query: 1414 IIADIRLDQLDESVTGKLPLQLSPDLRRTGNRFAQPRPVAAAADTIAIIGHSGAVISEME 1473 II +I L G + +S D+ + R Q ++ + + + + +E Sbjct: 1437 IIGEIDYKVLGVH-KGLIKFLISSDILQ---RIDQTVSKEKISEEMNFVRVNHIDYNSIE 1492 Query: 1474 QAVAQLWAKTFGLKKMDISKNFYELGGDSIMATQMANLLNTQLHQKLSIAEIFEYPTVSG 1533 + ++W K GL+++ I FY+LGGDSI A + + + ++ +++IF YP++ Sbjct: 1493 NKILKVWIKVLGLEQIGIDDKFYDLGGDSISAIYLMKEIEKEFPSRIDVSDIFTYPSIRE 1552 Query: 1534 LAAYLEQSLPSRNEAT 1549 +A Y+E L + ++ Sbjct: 1553 MALYIESELKNDDDCV 1568 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.406 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 14,588,730,554 Number of extensions: 634656313 Number of successful extensions: 1582050 Number of sequences better than 1.0e-05: 18420 Number of HSP's gapped: 1496068 Number of HSP's successfully gapped: 28895 Length of query: 2437 Length of database: 3,060,696,203 Length adjustment: 153 Effective length of query: 2284 Effective length of database: 1,619,280,908 Effective search space: 3698437593872 Effective search space used: 3698437593872 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 140 (58.5 bits)