BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0486.0007.p (549 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KCQ7.1 B3KCQ7_9BACI Response regulator receiver 548 e-154 C0Z4C7.1 C0Z4C7_BREBN Probable two-component response regulator 533 e-149 B1DIU4.1 B1DIU4_9BACL Two component transcriptional regulator, A... 496 e-138 C4IM91.1 C4IM91_CLOBU Response regulator receiver protein 367 2e-99 B1QZD7.1 B1QZD7_CLOBU Transcriptional regulator 367 2e-99 >B3KCQ7.1 B3KCQ7_9BACI Response regulator receiver Length = 544 Score = 548 bits (1411), Expect = e-154, Method: Compositional matrix adjust. Identities = 276/549 (50%), Positives = 378/549 (68%), Gaps = 6/549 (1%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 MYK++L +DE DVREG++ +I WE GFE+ AENGREA ++ +RL PDVV+TDI MPF Sbjct: 1 MYKVLLVDDEADVREGLVQEIQWEACGFEIKGTAENGREAVEAAERLEPDVVITDISMPF 60 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 +GLQLA W+R P KI+ILTGYDEF+YA++AI L +DEY+LKPFSA+ +++L K++ Sbjct: 61 QDGLQLASWLREHQPLCKIVILTGYDEFDYARQAITLSVDEYLLKPFSAESFMELLGKIK 120 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 I+ E+AE+E+V L EHYR SLP+LRE FL+SL++R+L + I EK+ YG+ L G Sbjct: 121 DKIDMEVAEREDVRQLKEHYRTSLPLLRESFLASLLTRKLPLSIIEEKTRNYGLPLNGAC 180 Query: 181 FQASVISVDYIREGGGGEAVSSRPVS-LRDTGDRNLQLFAVLNIAEEICQKHSFGKVFIH 239 + A+V+++ E S P S LR +GD +L L A+LNIA+E+ SFG FI+ Sbjct: 181 YLAAVMAL-----YPAAEHKESAPSSSLRHSGDMDLMLHAMLNIAKELMDPLSFGSAFIY 235 Query: 240 RDNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQSFN 299 +D+ S G L+ + +++ +LKL VT G G+ + S L S+ Sbjct: 236 QDSIVFLITNDGCEDESWFGDLQVALDRLLKSILHYLKLPVTIGVGSRVRTLSDLKHSYQ 295 Query: 300 DALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVVDEL 359 DAL ALDYRLILG +VI+I+DVES + DEL +Q+LIR +KLGT +EL E + + Sbjct: 296 DALLALDYRLILGAEKVIFIDDVESPRQEGIRLDELQEQALIRNLKLGTAEELSEAITHI 355 Query: 360 FGGLDAAQVSTQEYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNNMGEAK 419 F L A + QE QI+LLE++T ILR AKESG EL + G G+ +EI KF+ + EAK Sbjct: 356 FDELIGASCTIQEVQIYLLEVVTAILRTAKESGIELEEMFGAGYQLHAEIFKFSGLQEAK 415 Query: 420 EWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDISIGRVCQHLHISTGYFSS 479 W+ V + I+ RQ +YK ++++A Y R HY + DIS+ ++C HLHISTGYFS Sbjct: 416 AWLQDVSLAIRKQISSSRQHAYKDIVEKALQYTREHYGDPDISLQKLCMHLHISTGYFSG 475 Query: 480 IFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRKKYGQSP 539 +FKKE+KMT+V YL+Q+R+E AKELLRST+LKAFEIAER+GFADPNYFSF F+K+ G SP Sbjct: 476 VFKKELKMTYVQYLMQLRMETAKELLRSTDLKAFEIAERVGFADPNYFSFSFKKQVGVSP 535 Query: 540 KEYKNSSRG 548 KEY+ +RG Sbjct: 536 KEYRAQARG 544 >C0Z4C7.1 C0Z4C7_BREBN Probable two-component response regulator Length = 534 Score = 533 bits (1373), Expect = e-149, Method: Compositional matrix adjust. Identities = 279/547 (51%), Positives = 366/547 (66%), Gaps = 18/547 (3%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 MYKLIL +DEEDVREG+ +IDW +G+EVV +AENGREA + ++RL PDVVVTDI+MPF Sbjct: 1 MYKLILVDDEEDVREGVSQEIDWHSHGYEVVAKAENGREALELVERLRPDVVVTDIKMPF 60 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 MNGLQLAE I +P +IIILTG+DEFEYAQKA+KLQIDEY+LKPFSA EL++ L KV+ Sbjct: 61 MNGLQLAESIGRDYPAIRIIILTGFDEFEYAQKAVKLQIDEYVLKPFSASELMEALDKVK 120 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 ++ E A +ENV +L + YRKSLPVLRE FLSSL+SR+L ++ K+ EYGI LR Sbjct: 121 RRMDEEAAHRENVQLLRDSYRKSLPVLREVFLSSLLSRQLVQHDVFSKACEYGIELRSPE 180 Query: 181 FQASVISVDYIREGGGGEAVSSRPVSLRDTGDRNLQLFAVLNIAEE-ICQKHSFGKVFIH 239 + +VI VD ++ ++ L LFAV NIAEE + G VF+H Sbjct: 181 YLVAVICVDQPKQE-----------------EQQLFLFAVKNIAEEQLNASKQAGIVFLH 223 Query: 240 RDNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQSFN 299 D I R I EEIR+ +++++ +TVT G G A + L S+ Sbjct: 224 EDQVVLLMRTKADDTQRIEVRAQHIAEEIRRTIEKYMSITVTIGIGNAVADIAALPYSYE 283 Query: 300 DALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVVDEL 359 DA+QALDY+ ILG NR+I I DVE + + DE + L+R IK+GT EL+ V+DEL Sbjct: 284 DAMQALDYKSILGCNRMIVINDVEKQASEQIRLDERREHELVRCIKMGTSTELRAVIDEL 343 Query: 360 FGGLDAAQVSTQEYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNNMGEAK 419 F + VS ++Y+I+LLEI+TTIL+ A + +++ G L + F M +A+ Sbjct: 344 FDQVAGVPVSIEDYRIYLLEIMTTILKTAHRAEVDMDQLFGGQRYLLQVMTTFTGMEDAR 403 Query: 420 EWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDISIGRVCQHLHISTGYFSS 479 E I +C RLM SIA RQ++Y++LI QA DY +HY DISI +VC+ LHIS GYFS Sbjct: 404 EQITDICERLMASIASGRQTTYRRLITQALDYTHAHYHSPDISIHKVCEQLHISLGYFSG 463 Query: 480 IFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRKKYGQSP 539 IFKKE K TFVSYLL +R+E AKELLR+T+LK+FEIAE++G+ DPNYFSF FRK G S Sbjct: 464 IFKKETKTTFVSYLLSLRMEKAKELLRTTDLKSFEIAEKVGYTDPNYFSFSFRKYTGMSA 523 Query: 540 KEYKNSS 546 KEY++ S Sbjct: 524 KEYRSQS 530 >B1DIU4.1 B1DIU4_9BACL Two component transcriptional regulator, AraC family Length = 550 Score = 496 bits (1278), Expect = e-138, Method: Compositional matrix adjust. Identities = 253/550 (46%), Positives = 363/550 (66%), Gaps = 13/550 (2%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 MYKL+L +DE +V EG++ +IDWE GF V A NG+EA + I+++ PDV++TDI MP+ Sbjct: 1 MYKLLLVDDEPEVTEGLMMEIDWESCGFSEVKTAGNGKEATELIEKMEPDVLITDISMPY 60 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 MNGL+LA+W++ +P T+++ILTG+DEFEYA++AI LQ++ Y+LKPFS +L + +L+V+ Sbjct: 61 MNGLELADWVKKMYPITRVVILTGHDEFEYAKQAINLQVENYLLKPFSGSQLTETVLQVK 120 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 ++ E + NV +L EHYR +LP++RE+FLSSL++R A I EK+ +YG+ L GE Sbjct: 121 QRMDEERETRNNVELLQEHYRMTLPIVREKFLSSLITRHQSLASIREKAEKYGMELDGEG 180 Query: 181 FQASVISVDYI----REGGGGEAVSSRPVSLRDTGDRNLQLFAVLNIAEEICQKHSFGKV 236 + SVISV + E AVSS D +L+LF++ NIA EI +H GKV Sbjct: 181 YVVSVISVLHSDKPEEELDPLHAVSS-------IKDLDLKLFSITNIAGEIWTRHQLGKV 233 Query: 237 FIHRDNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQ 296 FIH+D + T L+EI Q+++RFLKL V G GT L Sbjct: 234 FIHQDQVVLFTVSPDGRDEEVMEATQDALKEILQSIERFLKLPVMIGVGTFTRDIRSLKY 293 Query: 297 SFNDALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVV 356 S+ A ALDYR ILG N++I I+D+E RV L +DE +Q+L+R+IK+GT EL EV+ Sbjct: 294 SYEAAEVALDYRRILGINQIICIDDMEERVQEKLIFDEWKEQNLVRSIKVGTELELAEVI 353 Query: 357 DELFGGLDAAQVSTQ--EYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNN 414 DELF L Q Q ++ +LLE++T I++++K + P L + K N Sbjct: 354 DELFDDLARVQAPVQVHNFEHYLLEMVTAIIKLSKMIDDGKDKDPIFAVGILDQYQKLNT 413 Query: 415 MGEAKEWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDISIGRVCQHLHIST 474 + E K W +C ++ IA RQ SYK ++++A + +S++ +S++SI VC HLHIST Sbjct: 414 LNETKAWFTDLCGKVRSRIASRRQHSYKHIVEEAIQFTKSNFNDSELSINVVCAHLHIST 473 Query: 475 GYFSSIFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRKK 534 GYFSS+FKKE+KMT+ +YLLQ+R+EAAKE LR+TELK FEIA+++GFADPNYFS CF+K Sbjct: 474 GYFSSLFKKEVKMTYGAYLLQLRMEAAKEYLRTTELKTFEIADKVGFADPNYFSLCFKKY 533 Query: 535 YGQSPKEYKN 544 G S KEY++ Sbjct: 534 AGVSAKEYRS 543 >C4IM91.1 C4IM91_CLOBU Response regulator receiver protein Length = 534 Score = 367 bits (942), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 193/547 (35%), Positives = 332/547 (60%), Gaps = 18/547 (3%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 +YK+++ +DEE++R GII +I WE YGF +V AENG+EA + ++L PDV++TDI+MPF Sbjct: 3 LYKVMIVDDEEEIRLGIIKKIKWEDYGFVIVGDAENGQEALEKAEKLQPDVIMTDIRMPF 62 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 MNGL+L E + P+ K+II +G D+FE+AQKAI++ + EY+LKP ++ E+I+VL +++ Sbjct: 63 MNGLELGEKLAAIMPSVKMIIFSGCDDFEFAQKAIRINVIEYVLKPINSIEVIEVLKRLK 122 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 ++ E EK NV +L ++Y SLPV++EQFL + R+ + + + + + + Sbjct: 123 INLDKEYDEKRNVEILYKYYIDSLPVIKEQFLVGAIEGRISEQQWDDMTKKLKLDINSRY 182 Query: 181 FQASVISVDY--IREGGGGEAVSSRPVSLRDTGDRNLQLFAVLNIAEEICQKHSFGKVFI 238 VI +DY + E S +S++ D N++ F C SF +++ Sbjct: 183 LSIGVIRLDYEQMSSNVFREEDSLMQISIKKVVDDNMENF---------CSFISF--LYL 231 Query: 239 HRDNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQSF 298 + + + G L E+ ++ R + L+++AG G C ++QS+ Sbjct: 232 DKVIVIGNFDEKQHVQSFVNG-----LNEVCRSFNRIVGLSISAGIGNICKVFGDITQSY 286 Query: 299 NDALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVVDE 358 +A AL+YR+I+G + I+IEDVE L DE T++ +I IK+ + +++ ++V + Sbjct: 287 KNAQSALEYRIIVGTGKAIYIEDVEPNTSMQLHLDENTERLMINAIKIESSKKISQIVTK 346 Query: 359 LFGGLDAAQVSTQEYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNNMGEA 418 LF + + VS EY++++ EII ++LR+ + +ND + F + + FN++ Sbjct: 347 LFDVYEISFVSFNEYKMYITEIIISLLRLIQSYNLNVNDIFKVNFNLYTFLDNFNSIDSI 406 Query: 419 KEWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDISIGRVCQHLHISTGYFS 478 KEWI+ ++ D I ER +S K LI++AK YI +Y + ++S+ ++C LH+S+ YFS Sbjct: 407 KEWIVDKALKINDCIKKERVNSSKILIEKAKLYITENYMDYELSVEKICSVLHVSSTYFS 466 Query: 479 SIFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRKKYGQS 538 ++FKKE +FV++L ++RLE A LL +T+ K + IAE +G+++ NYFS+ F+KK+G S Sbjct: 467 TMFKKETGKSFVNFLTELRLEQAITLLNTTDYKTYIIAENVGYSEANYFSYVFKKKFGMS 526 Query: 539 PKEYKNS 545 P +Y+ S Sbjct: 527 PSKYRKS 533 >B1QZD7.1 B1QZD7_CLOBU Transcriptional regulator Length = 534 Score = 367 bits (942), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 193/547 (35%), Positives = 332/547 (60%), Gaps = 18/547 (3%) Query: 1 MYKLILAEDEEDVREGIIAQIDWEQYGFEVVDQAENGREAADSIDRLLPDVVVTDIQMPF 60 +YK+++ +DEE++R GII +I WE YGF +V AENG+EA + ++L PDV++TDI+MPF Sbjct: 3 LYKVMIVDDEEEIRLGIIKKIKWEDYGFVIVGDAENGQEALEKAEKLQPDVIMTDIRMPF 62 Query: 61 MNGLQLAEWIRNRHPNTKIIILTGYDEFEYAQKAIKLQIDEYILKPFSAQELIDVLLKVR 120 MNGL+L E + P+ K+II +G D+FE+AQKAI++ + EY+LKP ++ E+I+VL +++ Sbjct: 63 MNGLELGEKLAAIMPSVKMIIFSGCDDFEFAQKAIRINVIEYVLKPINSIEVIEVLKRLK 122 Query: 121 SAIEAEIAEKENVFVLSEHYRKSLPVLREQFLSSLVSRRLRPAEIAEKSAEYGIHLRGEL 180 ++ E EK NV +L ++Y SLPV++EQFL + R+ + + + + + + Sbjct: 123 INLDKEYDEKRNVEILYKYYIDSLPVIKEQFLVGAIEGRISEQQWDDMTKKLKLDINSRY 182 Query: 181 FQASVISVDY--IREGGGGEAVSSRPVSLRDTGDRNLQLFAVLNIAEEICQKHSFGKVFI 238 VI +DY + E S +S++ D N++ F C SF +++ Sbjct: 183 LSIGVIRLDYEQMSSNVFREEDSLMQISIKKVVDDNMENF---------CSFISF--LYL 231 Query: 239 HRDNXXXXXXXXXXXXASITGRTYAILEEIRQNVQRFLKLTVTAGSGTACHSPSLLSQSF 298 + + + G L E+ ++ R + L+++AG G C ++QS+ Sbjct: 232 DKVIVIGNFDEKQHVQSFVNG-----LNEVCRSFNRIVGLSISAGIGNICKVFGDITQSY 286 Query: 299 NDALQALDYRLILGNNRVIWIEDVESRVGRMLAYDELTQQSLIRTIKLGTLQELKEVVDE 358 +A AL+YR+I+G + I+IEDVE L DE T++ +I IK+ + +++ ++V + Sbjct: 287 KNAQSALEYRIIVGTGKAIYIEDVEPNTSMQLHLDENTERLMINAIKIESSKKISQIVTK 346 Query: 359 LFGGLDAAQVSTQEYQIFLLEIITTILRVAKESGSELNDYPGLGFTSLSEIHKFNNMGEA 418 LF + + VS EY++++ EII ++LR+ + +ND + F + + FN++ Sbjct: 347 LFDVYEISFVSFNEYKMYITEIIISLLRLIQSYNLNVNDIFKVNFNLYTFLDNFNSIDSI 406 Query: 419 KEWIIGVCSRLMDSIAMERQSSYKQLIDQAKDYIRSHYEESDISIGRVCQHLHISTGYFS 478 KEWI+ ++ D I ER +S K LI++AK YI +Y + ++S+ ++C LH+S+ YFS Sbjct: 407 KEWIVDKALKINDCIKKERVNSSKILIEKAKLYITENYMDYELSVEKICSVLHVSSTYFS 466 Query: 479 SIFKKEMKMTFVSYLLQIRLEAAKELLRSTELKAFEIAERIGFADPNYFSFCFRKKYGQS 538 ++FKKE +FV++L ++RLE A LL +T+ K + IAE +G+++ NYFS+ F+KK+G S Sbjct: 467 TMFKKETGKSFVNFLTELRLEQAITLLNTTDYKTYIIAENVGYSEANYFSYVFKKKFGMS 526 Query: 539 PKEYKNS 545 P +Y+ S Sbjct: 527 PSKYRKS 533 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.381 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,959,817,843 Number of extensions: 114820736 Number of successful extensions: 398947 Number of sequences better than 1.0e-05: 14524 Number of HSP's gapped: 410698 Number of HSP's successfully gapped: 15165 Length of query: 549 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 408 Effective length of database: 1,732,333,088 Effective search space: 706791899904 Effective search space used: 706791899904 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)