BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0479.0023.p (601 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C0Z8Y2.1 C0Z8Y2_BREBN Putative adenine deaminase EC=3.5.4.2 781 0.0 Q1AZ25.1 ADEC_RUBXD Adenine deaminase EC=3.5.4.2 679 0.0 Q2RL95.1 ADEC_MOOTA Adenine deaminase EC=3.5.4.2 487 e-135 Q98NF9.1 ADEC_RHILO Adenine deaminase EC=3.5.4.2 484 e-135 A4EGR4.1 A4EGR4_9RHOB Adenine deaminase 484 e-134 >C0Z8Y2.1 C0Z8Y2_BREBN Putative adenine deaminase EC=3.5.4.2 Length = 609 Score = 781 bits (2016), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/603 (64%), Positives = 456/603 (75%), Gaps = 4/603 (0%) Query: 2 SFTRKPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKD 61 SF R PLADC+P+LVA +RG+ ATL I G LVNV SGEIL MS+AV G RIAYVG Sbjct: 7 SFARPPLADCIPDLVAFSRGEKKATLFIHNGTLVNVLSGEILPNMSIAVVGTRIAYVGPF 66 Query: 62 VSHMIGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIA 121 V M E T +I+A G+Y+APG+LDGHCHIES+ L+VT+FA AVLPLGTTGGFFDAHEI+ Sbjct: 67 VEGMTDESTTIIDAKGKYMAPGLLDGHCHIESSMLSVTQFANAVLPLGTTGGFFDAHEIS 126 Query: 122 NVFGLKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVI 181 NV GL G+R+ML+E R TP+AAYMQVASCVPS FET GA GP EVAEA +WG D+I Sbjct: 127 NVLGLPGLRIMLDEARQTPMAAYMQVASCVPSTDASFETAGAEFGPAEVAEALSWGPDMI 186 Query: 182 ALGEVMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECV 241 ALGEVMNFPGVVYGD KM+GEIQATLRAG+VVDGH+TWP+ D RL YAAAGVTGDHECV Sbjct: 187 ALGEVMNFPGVVYGDPKMIGEIQATLRAGKVVDGHYTWPSSDPRLAAYAAAGVTGDHECV 246 Query: 242 TAEDVIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGH 301 T+EDV +RVRLGMYA+MRRGSAWHDVA TI AHTE G+D RRM+LV+DDR +SL++EGH Sbjct: 247 TSEDVAQRVRLGMYAKMRRGSAWHDVAATIKAHTEQGIDSRRMMLVSDDRICDSLKEEGH 306 Query: 302 MDFVVRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVV 361 M+F+VRHAISQGVKPVTAFQMATINTAERFGVARD+GSI PG ADIILLDGNLADV+VV Sbjct: 307 MNFIVRHAISQGVKPVTAFQMATINTAERFGVARDVGSIAPGIIADIILLDGNLADVNVV 366 Query: 362 MTIAAGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIR 421 TIA G VVAENG MT L+P+ YP + SV + DF+I+ P+ SG++ TRV Sbjct: 367 TTIARGEVVAENGEMTLELSPFPYPEFAINSVKIKAELTPSDFIIKTPVPSGTIKTRVAV 426 Query: 422 VIENHVETEELILDLPVSEGRLQVG--NGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAA 479 V ENHVETEE+ +D+ V+ G LQ+ + LCK+AV ERH TG +G+ +GF++PAA Sbjct: 427 VRENHVETEEVFVDVAVANGELQITPESTLCKMAVFERHGKTGGSGIGIVGNVGFNQPAA 486 Query: 480 IAMTVAHDSHNVLVIGNDDGLMXXXXXXXXXXXXXXXXXXXXXXXL-FPLAIAGLMSVEP 538 IAMTVAHD HNVLVIGNDD M + PL +AGLMS EP Sbjct: 487 IAMTVAHDCHNVLVIGNDDERMAQAANAVISMQGGIAVVTGDGEMVELPLRLAGLMSTEP 546 Query: 539 FEMXXXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRISPEEGIKLVS 598 +E L +GCT+NYAFMTLSLLAL VIPTL ISD GL+RIS + G + VS Sbjct: 547 YETVVQQSMEISQALVKAGCTMNYAFMTLSLLALVVIPTLHISDTGLIRIS-DAGFERVS 605 Query: 599 LFV 601 LFV Sbjct: 606 LFV 608 >Q1AZ25.1 ADEC_RUBXD Adenine deaminase EC=3.5.4.2 Length = 606 Score = 679 bits (1753), Expect = 0.0, Method: Compositional matrix adjust. Identities = 365/597 (61%), Positives = 430/597 (72%), Gaps = 3/597 (0%) Query: 5 RKPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSH 64 RKPL + EL ATARGDLPATLVI G LV+V SGE+L GMSVAV+G RIAYVG D H Sbjct: 7 RKPLYEMTRELAATARGDLPATLVIRDGTLVSVTSGEVLPGMSVAVRGPRIAYVGPDAGH 66 Query: 65 MIGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVF 124 +G T VI+AAGRYIAPG LDGHCHIES+Q+TVT+FARAVLPLGTTGGFFDAHEI NV Sbjct: 67 TVGPQTTVIDAAGRYIAPGFLDGHCHIESSQITVTQFARAVLPLGTTGGFFDAHEITNVL 126 Query: 125 GLKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALG 184 GL+G+RLML+E R TPLAAY++VASCVPS E ET GA IGPEEVAEA +WGEDVIALG Sbjct: 127 GLRGLRLMLDEARSTPLAAYLEVASCVPSTSTELETPGAVIGPEEVAEALSWGEDVIALG 186 Query: 185 EVMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTAE 244 EVMNFPGVV+GD +M EI A LRAG++ DGHF WP DD RL YAA+G++G HE T E Sbjct: 187 EVMNFPGVVFGDERMHAEISAALRAGKIADGHFCWPPDDHRLAAYAASGISGCHEGTTPE 246 Query: 245 DVIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDF 304 D + R+R GMYA++RRGSAWHDVA TI AHTE GLDPRR+LLVTDDRS ESL +EGHMDF Sbjct: 247 DTLWRLRQGMYAKLRRGSAWHDVAATIKAHTERGLDPRRILLVTDDRSPESLLEEGHMDF 306 Query: 305 VVRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTI 364 VVRHAI+QGV PVTAFQMAT+N AERF V+ D+GS+TPG ADI+LL+G+LA+V V +T+ Sbjct: 307 VVRHAIAQGVNPVTAFQMATLNPAERFRVSHDVGSVTPGRYADILLLEGDLAEVRVSLTV 366 Query: 365 AAGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVIE 424 AAG VVAE G M A L PY YP L +V + EDF I AP R IRV+E Sbjct: 367 AAGEVVAEGGRMVAELEPYDYPAFCLDTVRVAGGLGPEDFDIPAPGGGERARVRAIRVVE 426 Query: 425 NHVETEELILDLPVSEG--RLQVGNGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIAM 482 NHVET ++LPV G RL +CK+ V+ERH G + G G+GF PAA+A Sbjct: 427 NHVETRGEWVELPVEGGLVRLDPRKDVCKLFVIERHGRGGGRGAGFVTGLGFERPAALAS 486 Query: 483 TVAHDSHNVLVIGNDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMSVEPFEMX 542 TVAHDSHN++V+GN + LM + PL +AGLMS EP+E Sbjct: 487 TVAHDSHNLMVLGNSEELMSRAAREVVAARGGVAVAVGGETAVLPLPVAGLMSPEPYEEV 546 Query: 543 XXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRISPEEGIKLVSL 599 L +GC +NYAFMT+SLLAL V+P L +SD+GLV + EEG +LV L Sbjct: 547 ARLSREIGRALRSAGCRMNYAFMTISLLALVVLPELHLSDRGLVEVG-EEGFRLVGL 602 >Q2RL95.1 ADEC_MOOTA Adenine deaminase EC=3.5.4.2 Length = 596 Score = 487 bits (1254), Expect = e-135, Method: Compositional matrix adjust. Identities = 277/586 (47%), Positives = 360/586 (61%), Gaps = 9/586 (1%) Query: 4 TRKPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVS 63 TR+PLA+ ELVA A G LPA VI GGK+VNV +GEIL +A++ GRIA VG DVS Sbjct: 4 TRRPLAEVTRELVAVATGKLPADTVIKGGKVVNVFTGEILP-WDIAIKNGRIASVG-DVS 61 Query: 64 HMIGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANV 123 +G T VI+A+G Y+ PG +DGH H+ES+ +TVT+FARAVLP GTT F D HEIANV Sbjct: 62 AAVGPETEVIDASGYYLCPGFMDGHVHVESSMVTVTQFARAVLPGGTTAIFMDPHEIANV 121 Query: 124 FGLKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIAL 183 G+ G++LM++E R PL + + SCVP+A P FE GAS GPEEVA A W + L Sbjct: 122 LGMDGVKLMVDEGRELPLKVFATMPSCVPAA-PGFEDAGASFGPEEVAAAMQW-PGICGL 179 Query: 184 GEVMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTA 243 GE+MNFPGV+ GD + GE++ATL AG+ + GHF PAD L Y AAG++ HE Sbjct: 180 GEMMNFPGVLAGDPAVHGELRATLAAGKPITGHFAMPADFQGLAGYTAAGISSCHESTRT 239 Query: 244 EDVIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMD 303 ED + R+RLGMYA MR GSAWHD+ TI + TE +D RR +LV+DD E+L GH++ Sbjct: 240 EDALNRLRLGMYAMMREGSAWHDIKATIKSLTETRVDSRRAMLVSDDTHPETLLSTGHLN 299 Query: 304 FVVRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMT 363 VVR AI +G+ P+ A Q TINTAE FGVA+D+G+I PG ADI+ L +LA V + Sbjct: 300 HVVRRAIEEGLNPIRAIQAVTINTAECFGVAQDLGAIAPGRYADILFLK-DLARVAIDKV 358 Query: 364 IAAGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVI 423 + G VVA G + L AYP V SVHL + F I AP V RV+ +I Sbjct: 359 MVDGRVVAAGGRLLVDLPAVAYPDRVRHSVHLKEPLTPWHFRINAPAGKSRVQVRVMEII 418 Query: 424 ENHVETEELILDLPVSEGRLQVG--NGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIA 481 E +V T L + +PV +G++ G L K+AV+ERH G G+ +G G GF + A+A Sbjct: 419 EANVNTRHLTVTVPVVDGQVTAGVEADLAKVAVVERHGGNGSIGLGFVRGFGF-KAGAVA 477 Query: 482 MTVAHDSHNVLVIG-NDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMSVEPFE 540 TVAHDSHN+L++G ND + L PL IAGLMS P E Sbjct: 478 STVAHDSHNLLIVGMNDADMALAGNTLAGCGGGMVAVRDGQVLALLPLPIAGLMSDRPVE 537 Query: 541 MXXXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLV 586 + GC L FMT++LL+L V+P LR++++GLV Sbjct: 538 EVAARLAAVHRAWQELGCRLVSPFMTMALLSLPVLPELRLTNRGLV 583 >Q98NF9.1 ADEC_RHILO Adenine deaminase EC=3.5.4.2 Length = 605 Score = 484 bits (1247), Expect = e-135, Method: Compositional matrix adjust. Identities = 280/601 (46%), Positives = 360/601 (59%), Gaps = 13/601 (2%) Query: 6 KPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSHM 65 KP + LV A G PA LVI G+ VNV SGEI+ G +A+ GGR AY G + SH Sbjct: 13 KPWTEMATHLVDVAMGRKPADLVIRNGRWVNVHSGEIIAGTDIAIAGGRFAYCGPNASHA 72 Query: 66 IGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVFG 125 IG+GT+V++A GRY+ PG+ D H H+ES +TVTEF RAV+P GTT F D HEIANV G Sbjct: 73 IGQGTKVVDAGGRYLVPGLCDAHMHVESGMVTVTEFCRAVIPHGTTSMFIDPHEIANVLG 132 Query: 126 LKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALGE 185 L G+RLM +E P+ ++Q+ SCVPSA P E GA + +VAEA TW E++I LGE Sbjct: 133 LPGVRLMHDEAVAMPINVHVQMPSCVPSA-PGLEHAGAELTVADVAEAMTW-ENIIGLGE 190 Query: 186 VMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPV--YAAAGVTGDHECVTA 243 VMNFPGV D M GEI AT+RAG+ V GH+ + D LP Y A G DHE A Sbjct: 191 VMNFPGVAANDPVMSGEIAATVRAGKTVGGHYA--SRDLGLPFHGYVAGGPEDDHEGTRA 248 Query: 244 EDVIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMD 303 ED I RVR GM A +R GSAW+DVA I A TE G+DPR +L TDD S +L EGHMD Sbjct: 249 EDAIARVRQGMKAMLRLGSAWYDVASQIKAVTEGGIDPRNFILCTDDSHSGTLVHEGHMD 308 Query: 304 FVVRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMT 363 VVRHAI QG+KPVTA QMATINTA+ F + R+IGSI PG AD++++ +LA + + Sbjct: 309 RVVRHAIQQGLKPVTAIQMATINTAQHFRLEREIGSIAPGRLADLLIVS-DLAAMTIDEV 367 Query: 364 IAAGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVI 423 A GV +A+ G + + Y YP +V L + A DF I AP + V RVI VI Sbjct: 368 YARGVRLAKGGKLDIDIPAYDYPKTAKNTVKLGKKLRAGDFDITAPKGANEVRVRVIGVI 427 Query: 424 ENHVETEELILDLPVSEGRLQVG--NGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIA 481 EN T L DLPV +G + + N +C+IA++ERH+GTG + +G G+ A+A Sbjct: 428 ENQAPTRALEADLPVEDGLVAMDRRNDVCQIALVERHRGTGGVTNAFVSGFGYMGDCAMA 487 Query: 482 MTVAHDSHNVLVIG-NDDGLMXXXXXXXXXXXXXXXXXXXXXXXLFPLAIAGLMSVEPFE 540 +VAHD+H+++ +G N + L + IAGLMS E E Sbjct: 488 SSVAHDAHHIICVGTNKQDMALAVNRLGQVGGGVVLFSKGKELALVEMPIAGLMSDERAE 547 Query: 541 MXXXXXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRISPEEGIKLVSLF 600 + + GC+LN A+M SLLAL VIP LRISD GL+ ++ + V LF Sbjct: 548 IVAAKAEKLTEAMRKMGCSLNNAYMQHSLLALVVIPELRISDVGLIDVTT---FQKVDLF 604 Query: 601 V 601 V Sbjct: 605 V 605 >A4EGR4.1 A4EGR4_9RHOB Adenine deaminase Length = 599 Score = 484 bits (1246), Expect = e-134, Method: Compositional matrix adjust. Identities = 278/588 (47%), Positives = 348/588 (59%), Gaps = 4/588 (0%) Query: 6 KPLADCVPELVATARGDLPATLVITGGKLVNVCSGEILEGMSVAVQGGRIAYVGKDVSHM 65 K AD P LVA A G A LVI GGKLVNV + EIL+G VAV GR AYVG D SH Sbjct: 6 KSWADVAPRLVAVAAGREKADLVIRGGKLVNVQTREILDGWQVAVAEGRFAYVGPDASHC 65 Query: 66 IGEGTRVIEAAGRYIAPGMLDGHCHIESTQLTVTEFARAVLPLGTTGGFFDAHEIANVFG 125 IG+ T+VIEA GRY+ PG+ DGH HIES LT EFA AV+P GTT F D HEIANV G Sbjct: 66 IGDDTQVIEAEGRYLIPGLCDGHMHIESGMLTPAEFAAAVIPHGTTTMFTDPHEIANVLG 125 Query: 126 LKGIRLMLEEMRGTPLAAYMQVASCVPSAGPEFETTGASIGPEEVAEAYTWGEDVIALGE 185 L+G+R+M +E P+ Y Q+ SC PSA P ETTG I +VAEA W +I LGE Sbjct: 126 LRGVRMMHDEALMQPVNIYTQMPSCAPSA-PGLETTGFEISAADVAEAMAW-PGIIGLGE 183 Query: 186 VMNFPGVVYGDSKMLGEIQATLRAGRVVDGHFTWPADDWRLPVYAAAGVTGDHECVTAED 245 +MNFPGV+ GD +ML E+ AT+ AG+ V GH+ P Y A G DHE + D Sbjct: 184 MMNFPGVINGDPQMLAEMAATMNAGKTVGGHYASPDKGVAFSAYVAGGAADDHEGTSEAD 243 Query: 246 VIERVRLGMYAQMRRGSAWHDVAKTITAHTEHGLDPRRMLLVTDDRSSESLRDEGHMDFV 305 I RVR GM + MR GSAW+DV ITA TE GLDPR +L TDD + +L ++GHM+ V Sbjct: 244 AIARVRNGMRSMMRLGSAWYDVESQITAVTEKGLDPRNFILCTDDCMAGTLVNDGHMNRV 303 Query: 306 VRHAISQGVKPVTAFQMATINTAERFGVARDIGSITPGSCADIILLDGNLADVHVVMTIA 365 +RHAI+ G PV A QMATINTA FG+ R+IGSI PG AD+IL +L + + IA Sbjct: 304 LRHAIACGCDPVIALQMATINTATHFGLEREIGSIAPGRRADVILTS-DLTTLPIEDVIA 362 Query: 366 AGVVVAENGIMTASLAPYAYPGEVLASVHLPQLPVAEDFVIRAPIESGSVLTRVIRVIEN 425 G VA +G +T Y +P + +VH+ ++ DF I+AP V +VI V+EN Sbjct: 363 RGRTVARDGKITVECPHYTWPDDARKTVHMGKVLGPSDFAIQAPEGKNKVKAKVIGVVEN 422 Query: 426 HVETEELILDLPVSEGRLQVGNGLCKIAVLERHKGTGNKSVGVAAGIGFHEPAAIAMTVA 485 TE L +LPV +G ++ +IA++ERH+GTG G +G G+ A+A TVA Sbjct: 423 QAPTEALTAELPVVDGLVEGEGDTYQIALVERHQGTGKVVNGFVSGFGYTGKMAMASTVA 482 Query: 486 HDSHNVLVIGNDDGLMXXXXXXXXXXXXXXXX-XXXXXXXLFPLAIAGLMSVEPFEMXXX 544 HDSH+++V+G D +M L L IAGLMS P Sbjct: 483 HDSHHMIVVGTDRAMMAAAGNRLGDVGGGVTVWKDGKELALVELPIAGLMSDSPAAEVAA 542 Query: 545 XXXXXXXXLYDSGCTLNYAFMTLSLLALAVIPTLRISDKGLVRISPEE 592 + GCTLN A+M SLLAL VIP+LRISD GLV + E Sbjct: 543 KADQMVAAMAACGCTLNNAYMQHSLLALVVIPSLRISDLGLVDVDKFE 590 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,284,157,508 Number of extensions: 135386231 Number of successful extensions: 344611 Number of sequences better than 1.0e-05: 541 Number of HSP's gapped: 342058 Number of HSP's successfully gapped: 547 Length of query: 601 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 459 Effective length of database: 1,722,912,073 Effective search space: 790816641507 Effective search space used: 790816641507 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)