BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0476.0072.p (475 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K6L7.1 B3K6L7_9BACI Sensor protein EC=2.7.13.3 568 e-160 C0ZJT4.1 C0ZJT4_BREBN Two-component sensor histidine kinase EC=2... 347 1e-93 B1Q5F3.1 B1Q5F3_CLOBO Sensor protein EC=2.7.13.3 296 4e-78 C3KZH3.1 C3KZH3_CLOB6 Sensor histidine kinase EC=2.7.3.- 295 5e-78 B1QQN7.1 B1QQN7_CLOBO Sensor protein EC=2.7.13.3 295 5e-78 >B3K6L7.1 B3K6L7_9BACI Sensor protein EC=2.7.13.3 Length = 484 Score = 568 bits (1463), Expect = e-160, Method: Compositional matrix adjust. Identities = 287/474 (60%), Positives = 357/474 (75%), Gaps = 2/474 (0%) Query: 1 MIKKGMRRQIVLHYXXXXXXXXXXXXXXXXXXXRTYYYDSVYSKITTHIGTAEDFLK-YE 59 +IKKG+RRQIVLHY R+YYYD+VY+ + HI TA DF + + Sbjct: 2 IIKKGIRRQIVLHYFLVVFIALLLIEVIFLIALRSYYYDTVYNHMVNHIRTANDFYQPFR 61 Query: 60 ISGERSPNQLQKLLDFFEMDYTELQVLTQDGNMLISSTGFQPDRTITTSDVPEAVGGSVG 119 ++ + NQL +++ FE+ TELQ+L G +L +STGF+ ++TI TSDV +A+ G+ Sbjct: 62 LTSSDNVNQLSEMVRHFELYNTELQILNPAGQVLSTSTGFEIEQTIKTSDVTQALAGNTS 121 Query: 120 RWVGRQPGTNESVMAVSKLVHINGRETYVIRYVTSMERIDSDLLNLTLVSIGIGSAVMAI 179 RW+G+Q GT + VMAVS+ V TY++RYVTS+E ++ L+ +TL ++ IG+AV+AI Sbjct: 122 RWIGKQQGTGQIVMAVSQSVSNGFENTYILRYVTSLEYVNDKLMKMTLFAVSIGAAVLAI 181 Query: 180 VVLFSFGLANSIVKPLKNITAVSAQMAKGKFTTRIKGDYRYEIGDLASTLNYMADEIIRS 239 V+ FS GLANSIVKPL NIT VSAQMAKGKF RIKGDY+YE+G+L+STLNYMA EI+RS Sbjct: 182 VLAFSIGLANSIVKPLNNITTVSAQMAKGKFNVRIKGDYKYELGELSSTLNYMAQEIVRS 241 Query: 240 NQIKDDFISSISHELRTPLTSIKGWSETLVSGGYDPEETKLGMGIISKESDRLIGLVEEI 299 NQ+KDDFISSISHELRTPLTSIKGWSETL SGGYDPEETK+GM IISKE+DRLIGLVEE+ Sbjct: 242 NQVKDDFISSISHELRTPLTSIKGWSETLDSGGYDPEETKIGMQIISKETDRLIGLVEEL 301 Query: 300 LDFSKLQQNEMKLSMGRVDIKVLLQETILNIWAKAEKKRIHLLLECEETFFIKGDANRLK 359 LDFSKLQQNEMKL G V+++ LLQE +LN+W KAEKK + + LE +E I GD NRLK Sbjct: 302 LDFSKLQQNEMKLVKGIVNLRELLQEIMLNLWTKAEKKGVQIKLESDEKPIIYGDVNRLK 361 Query: 360 QVFLNLVDNAVKFSPEDSSIVLSAQRLTGSELAVIVRDSGIGISEAHLGRVRDRFFQVDA 419 QVFLN+VDNAVKFS E+ I LS + + V V+D GIGIS+ HL RV+DRFFQV+ Sbjct: 362 QVFLNIVDNAVKFSHENGVINLSFA-MEEKFVIVTVQDHGIGISDEHLRRVKDRFFQVNP 420 Query: 420 LNGGTGLGLAISQQIVELHGGKLEMDSELGKGTQVTVILPMTEELPPEAPQAEN 473 LNGGTGLGLAI+QQ+VELHGG +EM+SELG GT V V LP+ E P A EN Sbjct: 421 LNGGTGLGLAITQQLVELHGGTMEMESELGHGTAVIVKLPLPEGKIPMAGGLEN 474 >C0ZJT4.1 C0ZJT4_BREBN Two-component sensor histidine kinase EC=2.7.3.- Length = 474 Score = 347 bits (890), Expect = 1e-93, Method: Compositional matrix adjust. Identities = 189/460 (41%), Positives = 283/460 (61%), Gaps = 4/460 (0%) Query: 4 KGMRRQIVLHYXXXXXXXXXXXXXXXXXXXRTYYYDSVYSKITTHIGTAEDFLKYEISGE 63 KG++ ++VLH+ TYY + + T T +F+ +G Sbjct: 12 KGIKSRLVLHFGLILLLIVLLLEGLFYWAVHTYYIGTATEALVTRSTTFTNFINKYATGY 71 Query: 64 RSPNQLQKLL-DFFEMDYTELQVLTQDGNMLISSTGFQPDRTITTSDVPEAVGGSVGRWV 122 R ++ + +L + +Y +++VL G ++++S GFQ I T DV +A+ G G ++ Sbjct: 72 RLKDKARYILENVSNQEYAKIEVLDPGGKVILNSYGFQTSEIINTPDVMDALKGQSGLYI 131 Query: 123 GRQPGTNESVMAVSKLVHINGRETYVIRYVTSMERIDSDLLNLTLVSIGIGSAVMAIVVL 182 G+ P + E V+AVS + +G V+RY S E + + + L G+G+ V+ + Sbjct: 132 GKSPQSRERVIAVSNPLTYSGEFVGVLRYTISAEPLYQAVNRIALYGAGVGTGVVILAFA 191 Query: 183 FSFGLANSIVKPLKNITAVSAQMAKGKFTTRIKGDYRYEIGDLASTLNYMADEIIRSNQI 242 S +A IV P++++T + QMA+G F+ R + E+G LA T NYMA EI ++ ++ Sbjct: 192 LSLLMAKRIVDPIEDLTNAAKQMAEGNFSVRAPKRFDDEVGTLADTFNYMATEIGKNEKL 251 Query: 243 KDDFISSISHELRTPLTSIKGWSETLVSGGY-DPEETKLGMGIISKESDRLIGLVEEILD 301 K+DFISS+SHELRTPLTSIKGW ETL+SGG +PEET LG+ +ISKE+DRLIGLVEE+LD Sbjct: 252 KNDFISSVSHELRTPLTSIKGWGETLISGGLEEPEETMLGLEVISKETDRLIGLVEELLD 311 Query: 302 FSKLQQNEMKLSMGRVDIKVLLQETILNIWAKAEKKRIHLLLECEET-FFIKGDANRLKQ 360 FSK Q EMKLS +D++ LLQ+ L +A K+I L LE T + GD NRLKQ Sbjct: 312 FSKFQSGEMKLSRVPMDVRELLQDLHLQFSVRAHAKQIELKLETPPTPLIVMGDPNRLKQ 371 Query: 361 VFLNLVDNAVKFSPEDSSIVLSAQRLTGSELAVIVRDSGIGISEAHLGRVRDRFFQVDAL 420 VF+NL+DNA+KF+P++ SIV++A L+ L V V D+G GI+ L V ++FF+ + Sbjct: 372 VFVNLLDNALKFTPQNGSIVIAAS-LSADRLLVTVTDTGEGINPEDLPHVTEKFFKGRSK 430 Query: 421 NGGTGLGLAISQQIVELHGGKLEMDSELGKGTQVTVILPM 460 G+GLGLAI ++I++LH G+ + S LG+GT + V LP+ Sbjct: 431 LSGSGLGLAICKEIIQLHAGRFSVSSALGQGTSIMVDLPL 470 >B1Q5F3.1 B1Q5F3_CLOBO Sensor protein EC=2.7.13.3 Length = 464 Score = 296 bits (757), Expect = 4e-78, Method: Compositional matrix adjust. Identities = 164/429 (38%), Positives = 261/429 (60%), Gaps = 3/429 (0%) Query: 34 RTYYYDSVYSKITTHIGTAEDFL-KYEISGERSPNQLQKLLDFFEMDYTELQVLTQDGNM 92 R YYY+++ I+ I T+ +F KY + N L + F+ ++Q++ G + Sbjct: 34 RHYYYNNLEDAISNQIKTSAEFYNKYFSNSPLEDNVLDNVDVFWRQTSAQVQIIDTKGKV 93 Query: 93 LISSTGFQPDRTITTSDVPEAVGGSVGRWVGRQPGTNESVMAVSKLVHINGRETYVIRYV 152 L+ S G I TSD+ +A+ G G W+G+ VMAV+ + + + V+R++ Sbjct: 94 LMDSIGVSNKSQIKTSDIQKALKGEKGVWIGKVDYDTSGVMAVTYPLKSDNQIVGVLRFI 153 Query: 153 TSMERIDSDLLNLTLVSIGIGSAVMAIVVLFSFGLANSIVKPLKNITAVSAQMAKGKFTT 212 TS+ ++SD+ ++L + IG V+ I L S LANSI +P+K +T V+ +MA G F Sbjct: 154 TSLRYVNSDIARISLGFLLIGLVVILISGLVSLFLANSITEPIKELTDVANKMASGNFKV 213 Query: 213 RIKGDYRYEIGDLASTLNYMADEIIRSNQIKDDFISSISHELRTPLTSIKGWSETLVSGG 272 + + + E G+L+ TLNYMADEI++ +Q+K++FISS+SHELRTPLTSIKGW+ TL S Sbjct: 214 KSEKMFDDEFGELSDTLNYMADEIVKKDQLKNEFISSVSHELRTPLTSIKGWAITLNSNE 273 Query: 273 YDPEETKLGMGIISKESDRLIGLVEEILDFSKLQQNEMKLSMGRVDIKVLLQETILNIWA 332 D E K G+ II ES+RL G+VEE+LDFSK +MKL+ ++I ++ + Sbjct: 274 VDKEILKDGLKIIEDESERLSGMVEELLDFSKFVSGKMKLNKEEINICEIIDTVRKQLEP 333 Query: 333 KAEKKRIHLLLECEETF-FIKGDANRLKQVFLNLVDNAVKFSPEDSSIVLSAQRLTGSEL 391 A + RI+ C I GD NR+KQV +NL+DNA KF+PE + L+ + + Sbjct: 334 YAYRNRINFKATCINKLPNIYGDRNRIKQVLINLLDNAFKFTPEGGLVELNT-KYEEEYI 392 Query: 392 AVIVRDSGIGISEAHLGRVRDRFFQVDALNGGTGLGLAISQQIVELHGGKLEMDSELGKG 451 ++V+D+G+GIS+ L RV+++F++ ++ G+GL+I +I++LH G L ++SE KG Sbjct: 393 TIVVKDTGVGISKEDLPRVKEKFYKGNSGKSKNGIGLSICDEIIKLHNGVLHIESEENKG 452 Query: 452 TQVTVILPM 460 T +++ LPM Sbjct: 453 TTISIKLPM 461 >C3KZH3.1 C3KZH3_CLOB6 Sensor histidine kinase EC=2.7.3.- Length = 464 Score = 295 bits (756), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 164/429 (38%), Positives = 261/429 (60%), Gaps = 3/429 (0%) Query: 34 RTYYYDSVYSKITTHIGTAEDFL-KYEISGERSPNQLQKLLDFFEMDYTELQVLTQDGNM 92 R YYY+++ I+ I T+ +F KY + N L + F+ ++Q++ G + Sbjct: 34 RHYYYNNLEDAISNQIKTSAEFYNKYFSNSPLEDNVLDNVDVFWRQTSAQVQIIDTKGKV 93 Query: 93 LISSTGFQPDRTITTSDVPEAVGGSVGRWVGRQPGTNESVMAVSKLVHINGRETYVIRYV 152 L+ S G I TSD+ +A+ G G W+G+ VMAV+ + + + V+R++ Sbjct: 94 LMDSIGVSNKSQIKTSDIQKALKGEKGVWIGKVDYDTSGVMAVTYPLKSDNQIVGVLRFI 153 Query: 153 TSMERIDSDLLNLTLVSIGIGSAVMAIVVLFSFGLANSIVKPLKNITAVSAQMAKGKFTT 212 TS+ ++SD+ ++L + IG V+ I L S LANSI +P+K +T V+ +MA G F Sbjct: 154 TSLRYVNSDIARISLGFLLIGLVVILISGLVSLFLANSITEPIKELTDVANKMASGNFKV 213 Query: 213 RIKGDYRYEIGDLASTLNYMADEIIRSNQIKDDFISSISHELRTPLTSIKGWSETLVSGG 272 + + + E G+L+ TLNYMADEI++ +Q+K++FISS+SHELRTPLTSIKGW+ TL S Sbjct: 214 KSEKMFDDEFGELSDTLNYMADEIVKKDQLKNEFISSVSHELRTPLTSIKGWAITLNSNE 273 Query: 273 YDPEETKLGMGIISKESDRLIGLVEEILDFSKLQQNEMKLSMGRVDIKVLLQETILNIWA 332 D E K G+ II ES+RL G+VEE+LDFSK +MKL+ ++I ++ + Sbjct: 274 VDKEILKDGLKIIEDESERLSGMVEELLDFSKFVSGKMKLNKEEINICEIIDTVRKQLEP 333 Query: 333 KAEKKRIHLLLECEETF-FIKGDANRLKQVFLNLVDNAVKFSPEDSSIVLSAQRLTGSEL 391 A + RI+ C I GD NR+KQV +NL+DNA KF+PE + L+ + + Sbjct: 334 YAYRNRINFKATCINKLPNIYGDRNRIKQVLINLLDNAFKFTPEGGLVELNT-KCEEEYI 392 Query: 392 AVIVRDSGIGISEAHLGRVRDRFFQVDALNGGTGLGLAISQQIVELHGGKLEMDSELGKG 451 ++V+D+G+GI++ L RV+++F++ ++ G+GL+I +I++LH G L ++SE KG Sbjct: 393 TIVVKDTGVGINKEDLPRVKEKFYKGNSGKSKNGIGLSICDEIIKLHNGVLHIESEENKG 452 Query: 452 TQVTVILPM 460 T ++V LPM Sbjct: 453 TTISVKLPM 461 >B1QQN7.1 B1QQN7_CLOBO Sensor protein EC=2.7.13.3 Length = 464 Score = 295 bits (756), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 164/429 (38%), Positives = 261/429 (60%), Gaps = 3/429 (0%) Query: 34 RTYYYDSVYSKITTHIGTAEDFL-KYEISGERSPNQLQKLLDFFEMDYTELQVLTQDGNM 92 R YYY+++ I+ I T+ +F KY + N L + F+ ++Q++ G + Sbjct: 34 RHYYYNNLEDAISNQIKTSAEFYNKYFSNSPLEDNVLDNVDVFWRQTSAQVQIIDTKGKV 93 Query: 93 LISSTGFQPDRTITTSDVPEAVGGSVGRWVGRQPGTNESVMAVSKLVHINGRETYVIRYV 152 L+ S G I TSD+ +A+ G G W+G+ VMAV+ + + + V+R++ Sbjct: 94 LMDSIGVSNKSQIKTSDIQKALKGEKGVWIGKVDYDTSGVMAVTYPLKSDNQIVGVLRFI 153 Query: 153 TSMERIDSDLLNLTLVSIGIGSAVMAIVVLFSFGLANSIVKPLKNITAVSAQMAKGKFTT 212 TS+ ++SD+ ++L + IG V+ I L S LANSI +P+K +T V+ +MA G F Sbjct: 154 TSLRYVNSDIARISLGFLLIGLVVILISGLVSLFLANSITEPIKELTDVANKMASGNFKV 213 Query: 213 RIKGDYRYEIGDLASTLNYMADEIIRSNQIKDDFISSISHELRTPLTSIKGWSETLVSGG 272 + + + E G+L+ TLNYMADEI++ +Q+K++FISS+SHELRTPLTSIKGW+ TL S Sbjct: 214 KSEKMFDDEFGELSDTLNYMADEIVKKDQLKNEFISSVSHELRTPLTSIKGWAITLNSNE 273 Query: 273 YDPEETKLGMGIISKESDRLIGLVEEILDFSKLQQNEMKLSMGRVDIKVLLQETILNIWA 332 D E K G+ II ES+RL G+VEE+LDFSK +MKL+ ++I ++ + Sbjct: 274 VDKEILKDGLKIIEDESERLSGMVEELLDFSKFVSGKMKLNKEEINICEIIDTVRKQLEP 333 Query: 333 KAEKKRIHLLLECEETF-FIKGDANRLKQVFLNLVDNAVKFSPEDSSIVLSAQRLTGSEL 391 A + RI+ C I GD NR+KQV +NL+DNA KF+PE + L+ + + Sbjct: 334 YAYRNRINFKATCINKLPNIYGDRNRIKQVLINLLDNAFKFTPEGGLVELNT-KCEEEYI 392 Query: 392 AVIVRDSGIGISEAHLGRVRDRFFQVDALNGGTGLGLAISQQIVELHGGKLEMDSELGKG 451 ++V+D+G+GI++ L RV+++F++ ++ G+GL+I +I++LH G L ++SE KG Sbjct: 393 TIVVKDTGVGINKEDLPRVKEKFYKGNSGKSKNGIGLSICDEIIKLHNGVLHIESEENKG 452 Query: 452 TQVTVILPM 460 T ++V LPM Sbjct: 453 TTISVKLPM 461 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.317 0.135 0.374 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,558,535,443 Number of extensions: 103802715 Number of successful extensions: 436843 Number of sequences better than 1.0e-05: 32617 Number of HSP's gapped: 362612 Number of HSP's successfully gapped: 32765 Length of query: 475 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 335 Effective length of database: 1,741,754,103 Effective search space: 583487624505 Effective search space used: 583487624505 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 133 (55.8 bits)