BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0476.0053.p (470 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K6M9.1 B3K6M9_9BACI Dihydrolipoyl dehydrogenase EC=1.8.1.4 785 0.0 B1DLS2.1 B1DLS2_9BACL Dihydrolipoyl dehydrogenase EC=1.8.1.4 655 0.0 C0ZER3.1 C0ZER3_BREBN Dihydrolipoyl dehydrogenase EC=1.8.1.4 610 e-173 P11959.2 DLDH1_BACST Dihydrolipoyl dehydrogenase EC=1.8.1.4 588 e-166 A4ILU9.1 A4ILU9_GEOTN Dihydrolipoyl dehydrogenase EC=1.8.1.4 586 e-165 >B3K6M9.1 B3K6M9_9BACI Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 471 Score = 785 bits (2026), Expect = 0.0, Method: Compositional matrix adjust. Identities = 381/469 (81%), Positives = 421/469 (89%) Query: 1 MVVGDASIEIDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALIS 60 MVVGDAS++IDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALI+ Sbjct: 1 MVVGDASLDIDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALIA 60 Query: 61 AAHQYEAAQHGEVFGVTAENVKVDWAKTQEFKNGVVKRMTTGVTSLMKGNKIEVFSGEAM 120 AAHQ+E+A+H + FG++ ENV VD+AKTQEFKNGVVK+MT GV L+KGNK+EVF+GE M Sbjct: 61 AAHQFESAKHADAFGISVENVTVDFAKTQEFKNGVVKKMTGGVAGLLKGNKVEVFNGECM 120 Query: 121 FISANEARLFNEHESPRYKFNNCIIATGSRPIELKPFPFGGRILSSTEALELPEIPKSMI 180 FI+ NEAR+FN+HESPRY+F NCIIATGSRPIELKPFPFGGRILSSTEAL LPE+PKSMI Sbjct: 121 FINENEARVFNDHESPRYRFKNCIIATGSRPIELKPFPFGGRILSSTEALNLPEVPKSMI 180 Query: 181 VIGGGYIGAELGQMYSKFGTKVTIIEGLDTVLPGFDKDMTRLVAKNMAKTGIEIVTNAKA 240 VIGGGYIGAELGQMYSKFG+KVTIIEGLD+VL GFDKDMT LV KNM KTGIEI+T AKA Sbjct: 181 VIGGGYIGAELGQMYSKFGSKVTIIEGLDSVLAGFDKDMTSLVTKNMKKTGIEIITGAKA 240 Query: 241 ESAVQNDKEVTVKYSVGGESKEVTADYLLVTVGRRPNTXXXXXXXXXXXXXXXRGLIKVD 300 ESA QNDKEVTVKYSV GE+KEVTADYLLVTVGRRPNT RG +KVD Sbjct: 241 ESAEQNDKEVTVKYSVNGETKEVTADYLLVTVGRRPNTDGELGLDLIGLDMDERGFVKVD 300 Query: 301 HQGRTNIPNIYAIGDIVPGLALAHKASYEGKIAAEAISGHKSVVDYKVIPAVVFTDPECS 360 HQGRT+IP+I+AIGDIV GLALAHKASYEGK+AAEAISG SVVDYK IPAVVFTDPECS Sbjct: 301 HQGRTSIPHIFAIGDIVSGLALAHKASYEGKVAAEAISGMPSVVDYKCIPAVVFTDPECS 360 Query: 361 SVGLTEKEAKDKGYTVKSGKFPFAGNGRAVSLNSPEGFIKIVANSENNLVLGAQIVGIEA 420 SVG TE +AK+KG+ VK+GKFP+AGNGR+VSLN PEGF+KIVA L+LGAQIVG+EA Sbjct: 361 SVGYTEAQAKEKGHKVKAGKFPYAGNGRSVSLNHPEGFVKIVAEEGTGLILGAQIVGLEA 420 Query: 421 SNLIAELGLAIEMGATLEDIALTIHAHPTLGEIVMEAAELVEGHPIHVV 469 SNLIAELGLAIEMGATLED+ALTIHAHPTLGEIVMEAAELV GHPIH++ Sbjct: 421 SNLIAELGLAIEMGATLEDVALTIHAHPTLGEIVMEAAELVMGHPIHII 469 >B1DLS2.1 B1DLS2_9BACL Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 471 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/469 (70%), Positives = 390/469 (83%) Query: 1 MVVGDASIEIDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALIS 60 MVVGD S++IDTLVIGAGPGGYVAAIRAAQLGQ VL+V+K +GGVCLN GCIPSKALIS Sbjct: 1 MVVGDPSLDIDTLVIGAGPGGYVAAIRAAQLGQNVLVVEKENVGGVCLNVGCIPSKALIS 60 Query: 61 AAHQYEAAQHGEVFGVTAENVKVDWAKTQEFKNGVVKRMTTGVTSLMKGNKIEVFSGEAM 120 A+HQYE+ H FG+TA +VKV+W K QEFKNG+VK++T GV SL+K NK++ F+GE M Sbjct: 61 ASHQYESISHASAFGITAGDVKVEWNKVQEFKNGIVKKLTGGVASLLKANKVQYFNGEVM 120 Query: 121 FISANEARLFNEHESPRYKFNNCIIATGSRPIELKPFPFGGRILSSTEALELPEIPKSMI 180 FI+ NEAR+FN+ E+PRY+F NCIIATGSRPIELK FPF GRI+SST AL LPEIPKS+I Sbjct: 121 FINENEARVFNDQEAPRYRFKNCIIATGSRPIELKAFPFSGRIVSSTGALSLPEIPKSII 180 Query: 181 VIGGGYIGAELGQMYSKFGTKVTIIEGLDTVLPGFDKDMTRLVAKNMAKTGIEIVTNAKA 240 VIGGGYIG ELGQMYSKFGTKVTIIEG D +LPGFDKDM +VAK + T ++IVT A A Sbjct: 181 VIGGGYIGIELGQMYSKFGTKVTIIEGGDAILPGFDKDMGSIVAKKLKGTNVDIVTGAMA 240 Query: 241 ESAVQNDKEVTVKYSVGGESKEVTADYLLVTVGRRPNTXXXXXXXXXXXXXXXRGLIKVD 300 + A Q DK+VT+ Y VG + ++VTADYLLVTVGRRPNT RGL++VD Sbjct: 241 QGAEQTDKDVTLTYKVGDKEEKVTADYLLVTVGRRPNTDGDLGLELANVKVGERGLVEVD 300 Query: 301 HQGRTNIPNIYAIGDIVPGLALAHKASYEGKIAAEAISGHKSVVDYKVIPAVVFTDPECS 360 Q RT+ P+IYAIGDI+ G ALAHKA YEG+IAAEAISG SV+DYK +PAV F+DPEC+ Sbjct: 301 AQCRTSNPHIYAIGDIIAGPALAHKAMYEGRIAAEAISGQPSVIDYKCVPAVCFSDPECA 360 Query: 361 SVGLTEKEAKDKGYTVKSGKFPFAGNGRAVSLNSPEGFIKIVANSENNLVLGAQIVGIEA 420 +VGL+EKEAKDKGY K GKFPFA NGRA+SLN+ EGF+K+V++++ LVLGAQI+G+EA Sbjct: 361 AVGLSEKEAKDKGYKTKVGKFPFAINGRAMSLNATEGFVKLVSDADTGLVLGAQIIGLEA 420 Query: 421 SNLIAELGLAIEMGATLEDIALTIHAHPTLGEIVMEAAELVEGHPIHVV 469 SN+IAEL LAIEMGATLEDIALTIHAHPTLGEIV++AAE+ GHPIH V Sbjct: 421 SNMIAELALAIEMGATLEDIALTIHAHPTLGEIVLDAAEVALGHPIHTV 469 >C0ZER3.1 C0ZER3_BREBN Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 469 Score = 610 bits (1573), Expect = e-173, Method: Compositional matrix adjust. Identities = 302/470 (64%), Positives = 370/470 (78%), Gaps = 1/470 (0%) Query: 1 MVVGDASIEIDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALIS 60 MVVG+ + E+D LVIGAGPGGYVAAIRAAQLG+ V +V+K+ELGGVCLN GCIPSKA+I Sbjct: 1 MVVGEFTTEVDVLVIGAGPGGYVAAIRAAQLGKTVAVVEKAELGGVCLNVGCIPSKAMIH 60 Query: 61 AAHQYEAAQHGEVFGVTAENVKVDWAKTQEFKNGVVKRMTTGVTSLMKGNKIEVFSGEAM 120 AAH YE QH E G+T ENVKVD+AK QE+K+G+VK++T GV SL KG+KI+V GEA+ Sbjct: 61 AAHTYEHTQHTESMGITMENVKVDFAKVQEWKSGIVKQLTGGVGSLFKGHKIQVIPGEAL 120 Query: 121 FISANEARLFNEHESPRYKFNNCIIATGSRPIELKPFPFGGRILSSTEALELPEIPKSMI 180 F+S NE R+F+ ++ RY+F +CIIATGSRPIEL FPFG R++SSTEAL + E+PKS++ Sbjct: 121 FVSENEVRVFHGYDVNRYRFQHCIIATGSRPIELPAFPFGKRVMSSTEALSMTELPKSLV 180 Query: 181 VIGGGYIGAELGQMYSKFGTKVTIIEGLDTVLPGFDKDMTRLVAKNMAKTGIEIVTNAKA 240 VIGGGYIG ELG +++KFGTKVTI+EG D +LPGF+ DM RLV + + K + I T A A Sbjct: 181 VIGGGYIGIELGTVFAKFGTKVTILEGSDQILPGFEPDMPRLVERKLKKLDVTIHTKALA 240 Query: 241 ESAVQNDKEVTVKYSVGGESKEVTADYLLVTVGRRPNTXXXXXXXXXXXXXXXRGLIKVD 300 + + + V V V GE +++ A+Y+LVTVGRRPNT RGLI VD Sbjct: 241 QGMEETENGVIVTAEVKGEQQKIEAEYVLVTVGRRPNT-DELGIRDIGMNMTDRGLIVVD 299 Query: 301 HQGRTNIPNIYAIGDIVPGLALAHKASYEGKIAAEAISGHKSVVDYKVIPAVVFTDPECS 360 QGRT+IPN+YAIGDIV G ALAHKASYEGK+AAEAI+GH + VDYK IPAVVF DPE + Sbjct: 300 KQGRTSIPNVYAIGDIVAGPALAHKASYEGKVAAEAIAGHPAEVDYKAIPAVVFCDPEIA 359 Query: 361 SVGLTEKEAKDKGYTVKSGKFPFAGNGRAVSLNSPEGFIKIVANSENNLVLGAQIVGIEA 420 SVG+ EKEAK+KG G+FPFA NGRA+S+N+ EG++K++A E NLVLGAQIVG EA Sbjct: 360 SVGINEKEAKEKGIDYIVGRFPFAANGRALSVNAGEGYVKLIAEKETNLVLGAQIVGPEA 419 Query: 421 SNLIAELGLAIEMGATLEDIALTIHAHPTLGEIVMEAAELVEGHPIHVVK 470 SN+IAE+GLAIEMGATLEDI LTIHAHPTLGE+ MEAAEL G PIHV+K Sbjct: 420 SNIIAEIGLAIEMGATLEDIELTIHAHPTLGEVTMEAAELALGRPIHVMK 469 >P11959.2 DLDH1_BACST Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 470 Score = 588 bits (1517), Expect = e-166, Method: Compositional matrix adjust. Identities = 292/469 (62%), Positives = 356/469 (75%), Gaps = 1/469 (0%) Query: 1 MVVGDASIEIDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALIS 60 MVVGD +IE +TLV+GAGPGGYVAAIRAAQLGQKV IV+K LGGVCLN GCIPSKALIS Sbjct: 1 MVVGDFAIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALIS 60 Query: 61 AAHQYEAAQHGEVFGVTAENVKVDWAKTQEFKNGVVKRMTTGVTSLMKGNKIEVFSGEAM 120 A+H+YE A+H E G+ AENV +D+AK QE+K VVK++T GV L+KGNK+E+ GEA Sbjct: 61 ASHRYEQAKHSEEMGIKAENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAY 120 Query: 121 FISANEARLFNEHESPRYKFNNCIIATGSRPIELKPFPFGGRILSSTEALELPEIPKSMI 180 F+ AN R+ N + Y F N IIATGSRPIEL F F RIL ST AL L E+PKS++ Sbjct: 121 FVDANTVRVVNGDSAQTYTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEVPKSLV 180 Query: 181 VIGGGYIGAELGQMYSKFGTKVTIIEGLDTVLPGFDKDMTRLVAKNMAKTGIEIVTNAKA 240 VIGGGYIG ELG Y+ FGTKVTI+EG +L GF+K M ++ K + K G+E+VTNA A Sbjct: 181 VIGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNALA 240 Query: 241 ESAVQNDKEVTVKYSVGGESKEVTADYLLVTVGRRPNTXXXXXXXXXXXXXXXRGLIKVD 300 + A + + VTV Y GE+K + ADY+LVTVGRRPNT RGLI+VD Sbjct: 241 KGAEEREDGVTVTYEANGETKTIDADYVLVTVGRRPNT-DELGLEQIGIKMTNRGLIEVD 299 Query: 301 HQGRTNIPNIYAIGDIVPGLALAHKASYEGKIAAEAISGHKSVVDYKVIPAVVFTDPECS 360 Q RT++PNI+AIGDIVPG ALAHKASYEGK+AAEAI+GH S VDY IPAVVF+DPEC+ Sbjct: 300 QQCRTSVPNIFAIGDIVPGPALAHKASYEGKVAAEAIAGHPSAVDYVAIPAVVFSDPECA 359 Query: 361 SVGLTEKEAKDKGYTVKSGKFPFAGNGRAVSLNSPEGFIKIVANSENNLVLGAQIVGIEA 420 SVG E++AKD+G V + KFPFA NGRA++LN +GF+K+V E+ +++GAQI+G A Sbjct: 360 SVGYFEQQAKDEGIDVIAAKFPFAANGRALALNDTDGFLKLVVRKEDGVIIGAQIIGPNA 419 Query: 421 SNLIAELGLAIEMGATLEDIALTIHAHPTLGEIVMEAAELVEGHPIHVV 469 S++IAELGLAIE G T EDIALTIHAHPTLGEI MEAAE+ G PIH++ Sbjct: 420 SDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEAAEVALGTPIHII 468 >A4ILU9.1 A4ILU9_GEOTN Dihydrolipoyl dehydrogenase EC=1.8.1.4 Length = 470 Score = 586 bits (1510), Expect = e-165, Method: Compositional matrix adjust. Identities = 293/469 (62%), Positives = 355/469 (75%), Gaps = 1/469 (0%) Query: 1 MVVGDASIEIDTLVIGAGPGGYVAAIRAAQLGQKVLIVDKSELGGVCLNRGCIPSKALIS 60 MVVGD +IE +TLV+GAGPGGYVAAIRAAQLGQKV IV+K+ LGGVCLN GCIPSKALIS Sbjct: 1 MVVGDFAIETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKANLGGVCLNVGCIPSKALIS 60 Query: 61 AAHQYEAAQHGEVFGVTAENVKVDWAKTQEFKNGVVKRMTTGVTSLMKGNKIEVFSGEAM 120 A H+YE A+H E G+ AENV VD++K QE+K VVK++T GV L+KGNK+E+ GEA Sbjct: 61 AGHRYEQAKHSEEMGIKAENVTVDFSKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAY 120 Query: 121 FISANEARLFNEHESPRYKFNNCIIATGSRPIELKPFPFGGRILSSTEALELPEIPKSMI 180 F+ AN R+ N + Y F N IIATGSRPIEL F F RIL ST AL L EIPKS++ Sbjct: 121 FVDANTVRVVNGDSAQTYTFKNAIIATGSRPIELPNFKFSNRILDSTGALNLGEIPKSLV 180 Query: 181 VIGGGYIGAELGQMYSKFGTKVTIIEGLDTVLPGFDKDMTRLVAKNMAKTGIEIVTNAKA 240 VIGGGYIG ELG Y+ FG KVTI+EG +L GF+K M ++ + + K G++IVTNA A Sbjct: 181 VIGGGYIGIELGTAYANFGAKVTILEGAGEILSGFEKQMAAIIKRRLKKKGVDIVTNALA 240 Query: 241 ESAVQNDKEVTVKYSVGGESKEVTADYLLVTVGRRPNTXXXXXXXXXXXXXXXRGLIKVD 300 + A + + VTV Y GE+K V ADY+LVTVGRRPNT RGLI+VD Sbjct: 241 KGAEEREDGVTVTYEANGETKTVDADYVLVTVGRRPNT-DELGLEQVGIKMTDRGLIEVD 299 Query: 301 HQGRTNIPNIYAIGDIVPGLALAHKASYEGKIAAEAISGHKSVVDYKVIPAVVFTDPECS 360 Q RT++PNI+AIGDIVPG ALAHKASYEGK+AAEAI+GH SVVDY IPAVVF+DPEC+ Sbjct: 300 QQCRTSVPNIFAIGDIVPGPALAHKASYEGKVAAEAIAGHPSVVDYVAIPAVVFSDPECA 359 Query: 361 SVGLTEKEAKDKGYTVKSGKFPFAGNGRAVSLNSPEGFIKIVANSENNLVLGAQIVGIEA 420 SVG E++AKD+G V + KFPFA NGRA++LN +GF+K+V E+ +V+GAQI+G A Sbjct: 360 SVGYFEQQAKDEGIDVITAKFPFAANGRALALNDTDGFLKLVVRKEDGVVIGAQIIGPNA 419 Query: 421 SNLIAELGLAIEMGATLEDIALTIHAHPTLGEIVMEAAELVEGHPIHVV 469 S++IAELGLAIE G T EDIALTIHAHPTLGEI ME AE+ G PIH++ Sbjct: 420 SDMIAELGLAIEAGMTAEDIALTIHAHPTLGEIAMEGAEVALGTPIHII 468 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.315 0.134 0.377 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,609,894,815 Number of extensions: 105843249 Number of successful extensions: 399479 Number of sequences better than 1.0e-05: 7083 Number of HSP's gapped: 371740 Number of HSP's successfully gapped: 7132 Length of query: 470 Length of database: 3,060,696,203 Length adjustment: 139 Effective length of query: 331 Effective length of database: 1,751,175,118 Effective search space: 579638964058 Effective search space used: 579638964058 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 133 (55.8 bits)