BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0475.0006.p (527 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value C4G2Z0.1 C4G2Z0_ABIDE Putative uncharacterized protein 317 2e-84 C0D1H3.1 C0D1H3_9CLOT Putative uncharacterized protein 308 9e-82 A4E7Q0.1 A4E7Q0_9ACTN Putative uncharacterized protein 259 5e-67 Q3Y037.1 Q3Y037_ENTFC Similar to metal-dependent hydrolase with ... 250 3e-64 Q3XZ05.1 Q3XZ05_ENTFC Similar to metal-dependent hydrolase with ... 231 2e-58 >C4G2Z0.1 C4G2Z0_ABIDE Putative uncharacterized protein Length = 511 Score = 317 bits (812), Expect = 2e-84, Method: Compositional matrix adjust. Identities = 182/520 (35%), Positives = 272/520 (52%), Gaps = 22/520 (4%) Query: 9 ADRVLLSNAVFTGIEDSVSPAFVALQGERIAAVGNPAEAKDWIGPKTFVHHLKDALIMPG 68 AD +LLSN +FTG+ F+A++ ++I AV N + + G TFV LK+ LI+PG Sbjct: 4 ADILLLSNYIFTGMSKEPINGFIAIKDDKIIAVEN-EHPELYYGENTFVLDLKNQLILPG 62 Query: 69 VHDNHVFFTGYMSMHRGVDLTHAAT----IDEALQLLRQDAENRPSEQNVYAYGWSEEGW 124 D H FFTGY+ G+DL + T I E +L D + G S Sbjct: 63 FVDTHCFFTGYLLSISGIDLKNCKTEGEVIHEITNILHTD------QDCFLGKGLSP--- 113 Query: 125 GQLPGQSL--LDEAFPDRAVIAINRTKSYCWMNTLAQHKYQFAPDECSAESRAHLLKDMM 182 L G S+ L E FPD A+I C+MN AQ K+ F PD+C +E LL ++ Sbjct: 114 -NLKGLSMTYLSEKFPDTAIILFTADGESCYMNHAAQEKFNFTPDKCYSEGYPKLLSYLL 172 Query: 183 QDRELVRQEFLDFARMLAKRGVTSIKDIGFDRHSXXXXXXXXXXXXXXXXXRVHFALEPV 242 +E R EFL++ +ML +G+TSIK++GFD S RVHF +PV Sbjct: 173 NQKENSRSEFLNYLKMLNSKGITSIKEMGFDDFSGFTDIIKDLENEQALTARVHFMSQPV 232 Query: 243 LQPLDIPAGLQYKERYQGEFLRFQGYKLMLDGVVADHTGDMLEPYADMPGVTTLRPVDYE 302 P+++ G Q +E++Q +F+RF G+ M DG ++ GDM PY P + + + Sbjct: 233 AFPMNLDYGSQMREKFQSDFVRFSGFNQMTDGSISQLEGDMKTPYLCAPTCCQ-KEIPWT 291 Query: 303 AIETAVQAADSHGIKCCLTAEGDAAIRKAVDILEGCSRRR-GDQRIRHSISDLEYPHPDD 361 +E V AD HG + L A+GDAAI K++ I C + + G + RH+I+DLE D Sbjct: 292 TLEEDVLNADKHGFRFSLHAQGDAAIAKSIAIFNKCQKNQDGTLKHRHAITDLECSDVLD 351 Query: 362 IRRMGENGIFAEVYAQIL-LLNPSYEEAYMSAVAGKENESRFYNYKSMLEANVPVTIGTD 420 + +MGE I E+Y QI+ + N + A + G ++N + M++ + ++ TD Sbjct: 352 LAKMGELNIIGEIYPQIMSITNRQDKIAMIEEKIGMNRGKNYWNRRKMIDNGITLSCATD 411 Query: 421 LPLFLTSVPDSLYAASFRLFSDGSPMGGWQPEQGMPAAEVLKAWTINGARHNGMEERTGT 480 LPL ++P+S+Y + F +G + E + AE+L AWT G + G E GT Sbjct: 412 LPLLFDNIPESIYHSVGGFFPEGGET--FNKENTITTAELLTAWTYGGQYNLGQENLLGT 469 Query: 481 LEAGKAADIAVFDRNLLDTTATEIRDAHVILTITAGQITY 520 LE GK ADI V D+N+ T +IR+ V +T+ G+I Y Sbjct: 470 LEVGKLADITVLDKNVFTLTFDDIRNVKVSMTMVNGKIVY 509 >C0D1H3.1 C0D1H3_9CLOT Putative uncharacterized protein Length = 514 Score = 308 bits (789), Expect = 9e-82, Method: Compositional matrix adjust. Identities = 187/516 (36%), Positives = 260/516 (50%), Gaps = 12/516 (2%) Query: 9 ADRVLLSNAVFTGIEDSVSPAFVALQGERIAAVGNPAEAKDWIGPKTFVHHLKDALIMPG 68 AD +L SNA+F G P FVA+ G RI A G P++ ++ G T +H L D LI PG Sbjct: 4 ADLLLRSNAIFDGSGREPQPGFVAVAGNRILASG-PSDGAEYAGENTEIHELGDRLICPG 62 Query: 69 VHDNHVFFTGYMSMHRGVDLTHAATIDEALQLLRQDAENRPSEQNVYAYGWSEEGWGQLP 128 D H FFTGY+ G DL +T +E L + V A G+G L Sbjct: 63 FVDVHCFFTGYLLTITGADLGGCSTEEEVLSAAKAYQNTLKPGATVLARN-VRPGFGGLT 121 Query: 129 GQSLLDEAFPDRAVIAINRTKSYCWMNTLAQHKYQFAPDECSAESRAHLLKDMMQDRELV 188 Q LD+ F I C+MN+ A Y F PD C +ES LL+ ++ D Sbjct: 122 -QEKLDQEFGATPAILFMEGGETCYMNSAAGAAYGFTPDTCWSESYWKLLRYILSDHSYS 180 Query: 189 RQEFLDFARMLAKRGVTSIKDIGFDRHSXXXXXXXXXXXXXXXXXRVHFALEPVLQPLDI 248 EF + M+ RG+TS+K++GFD RVHF +PV P+++ Sbjct: 181 VPEFKKYLAMMNSRGITSVKEMGFDDFYGFTEALAELEQGQELTARVHFMSQPVGAPMNL 240 Query: 249 PAGLQYKERYQGEFLRFQGYKLMLDGVVADHTGDMLEPYADMPGVTTLRPVDYEAIETAV 308 G ++++QG+F+ F GY M DG ++ G+M +PY + +D+E ++ Sbjct: 241 EYGKSMRDKFQGDFVSFSGYNQMTDGSISQLEGEMKKPYL-CADTCCAKDIDWEGLKRDT 299 Query: 309 QAADSHGIKCCLTAEGDAAIRKAVDILEGCSR-RRGDQRIRHSISDLEYPHPDDIRRMGE 367 AAD G + L A+GD AI K VDI E C R G + R +I+DLE P D+ RMG Sbjct: 300 LAADKEGFRFSLHAQGDGAIGKTVDIFEQCQRDENGKMKNRQAITDLECSDPADLERMGR 359 Query: 368 NGIFAEVYAQILLLNPSYEEAYMSAVAGKENESRFY-NYKSMLEANVPVTIGTDLPLFLT 426 GI AEVY QI+ + + M + RFY N + M ++ V ++ GTDLPL Sbjct: 360 LGIIAEVYPQIMSIADRAGKIAMIEEKIGMDRGRFYWNRRKMADSGVTISCGTDLPLLYD 419 Query: 427 SVPDSLYAASFRLFSDGSPMGG--WQPEQGMPAAEVLKAWTINGARHNGMEERTGTLEAG 484 +P+S+Y LF P GG + E + AE+LKAWT G + G E+ GTLEAG Sbjct: 420 DIPESVYHTVGGLF----PEGGEPFNKENTLTVAELLKAWTSGGQYNLGREQELGTLEAG 475 Query: 485 KAADIAVFDRNLLDTTATEIRDAHVILTITAGQITY 520 K ADIAV D NL D + R V +T+ G++ Y Sbjct: 476 KLADIAVLDGNLFDVDPAKARGMKVFMTLVNGRVVY 511 >A4E7Q0.1 A4E7Q0_9ACTN Putative uncharacterized protein Length = 527 Score = 259 bits (662), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 169/522 (32%), Positives = 254/522 (48%), Gaps = 18/522 (3%) Query: 12 VLLSNAVFTGIEDSVSPAFVALQGERIAAVGNPAEAKDWIGPKTFVHHLKDALIMPGVHD 71 VL S +VFTG D FVA++G RI AVG E ++ V L D +MPG+ D Sbjct: 7 VLTSKSVFTGTGDLPFEGFVAVRGNRIEAVGTKCEVASYLTQADEVVDLGDRTVMPGLID 66 Query: 72 NHVFFTGYMSMHRGVDLTHAATIDEALQLLRQDAENRPSEQNVYAYGWSEEGWGQLPG-- 129 H F+TG+ G DL+ A EA+ LLR E+ P + + E Sbjct: 67 VHTFYTGWALRTLGSDLSGIADAKEAVSLLRAWKEDHPDCAAAFGHNLPETLASDAENAN 126 Query: 130 -QSLLDEAFPDRAVIAINRTKSYCWMNTLAQHKYQFAPDECSAESRAHLLKDMMQDRELV 188 ++ D+ F D V+ C +N A +Y F P C AE ++ D + E V Sbjct: 127 TAAVFDDCFGDIPVVCFTPGAGTCVLNAAASARYGFTPQACYAEKIWRMMSDFLALPE-V 185 Query: 189 RQEFLDFARMLAKRGVTSIKDIGFDRHSXXXXXXXXXXXXXXXXXRVHFALEPVLQPLDI 248 R + D+ ML +RGVT+IK++ FD + RV +PV ++ Sbjct: 186 RAGYSDYMSMLNERGVTAIKEMAFDDYYGFADEMARREESGELTVRVSMMSQPVGAGANL 245 Query: 249 PAGLQYKERYQGEFLRFQGYKLMLDGVVADHTGDMLEPYADM-----PGVTTLRPVDYEA 303 + +ER++G F+RF G+ M D V +M++PY D G T + +++ Sbjct: 246 AYAREARERFRGPFVRFSGFNRMTDRGVWAGLAEMIDPYEDTADAGAAGKTVVEEPEWDL 305 Query: 304 IETAVQAADSHGIKCCLTAEGDAAIRKAVDILEGCSR-RRGDQRIRHSISDLEYPHPDDI 362 IE ++A D+ G + L +GD A+R+ V + R G RH+I+DLE P D+ Sbjct: 306 IENELRAIDADGFRYSLHCQGDGAVRRTVALYASLPRDEHGRMLRRHAITDLENSDPTDL 365 Query: 363 RRMGENGIFAEVYAQILLLNPSYEEAYMSAVAGKENESRF---YNYKSMLEANVPVTIGT 419 G+ G EVY QIL L+ E +S + + E+R +N + M ++ V GT Sbjct: 366 VEFGKLGGICEVYPQILTLD--RREDCLSMMRRQIGETRLLHSWNRRGMEDSGCTVCCGT 423 Query: 420 DLPLFLTSVPDSLYAASFRLFSDGSPMGGWQPEQGMPAAEVLKAWTINGARHNGMEERTG 479 DLPL + S+ +S+Y+A F+DG P+ + E+L+AWT GA E+ G Sbjct: 424 DLPLLIPSLGESIYSACGGFFADGLPV---NEVNTLTLVELLRAWTAGGAYDLMREDELG 480 Query: 480 TLEAGKAADIAVFDRNLLDTTATEIRDAHVILTITAGQITYD 521 TLE GK ADI V DR++ D + RD V +T++ GQI +D Sbjct: 481 TLEVGKLADICVLDRDVFDLDYRDARDLAVDMTMSDGQIVFD 522 >Q3Y037.1 Q3Y037_ENTFC Similar to metal-dependent hydrolase with the TIM-barrel fold Length = 524 Score = 250 bits (638), Expect = 3e-64, Method: Compositional matrix adjust. Identities = 144/514 (28%), Positives = 258/514 (50%), Gaps = 14/514 (2%) Query: 12 VLLSNAVFTGIEDSVSPAFVALQGERIAAVG--NPAEAKDWIGPKTFVHHLKDALIMPGV 69 V+ S+ ++T S ++ ++G I ++ NP +D TF+ K+ L+ G Sbjct: 8 VIRSSKIYTKKGFSPESGYIFIEGNIIKSITKENPISDEDV----TFID-CKNGLVTAGN 62 Query: 70 HDNHVFFTGYMSMHRGVDLTHAATIDEALQLLRQDAENRPSEQNVYAYGWSEEGWGQLPG 129 D+H FF+G+ G D + T ++ L ++ + + ++ Sbjct: 63 VDSHCFFSGHAMNFIGEDFSDVQTSNDLFTKLSHLTNLEDNKAIILGHDLPQKFTNSKYA 122 Query: 130 QSLLDEAFPDRAVIAINRTKSYCWMNTLAQHKYQFAPDECSAESRAHLLKDMMQDRELVR 189 + L ++ FPD + + C +N+ A+ ++ F C E+ LL + D++ ++ Sbjct: 123 KKL-NKLFPDIPTVIMASGAETCLLNSAAESRFNFTSQTCYPEAYWRLLHYVFSDKKFIK 181 Query: 190 QEFLDFARMLAKRGVTSIKDIGFDRHSXXXXXXXXXXXXXXXXXRVHFALEPVLQPLDIP 249 F+ + + L RG+T+IK++GFD RV+F +PV + ++I Sbjct: 182 PLFVSYMKFLNSRGITAIKEMGFDDFYGFTDILKELEESSDLSLRVNFMSQPVSEKMNID 241 Query: 250 AGLQYKERYQGEFLRFQGYKLMLDGVVADHTGDMLEPYADMPGVTTLRPVDYEAIETAVQ 309 + + G+ +RF G+ M DG +++ GD+ +PY + +T + +D+ IE ++ Sbjct: 242 YAKKMSALFTGDAIRFSGFNKMTDGSISEMKGDLKQPYTNNSEITNIEKIDWNEIERDLK 301 Query: 310 AADSHGIKCCLTAEGDAAIRKAVDILEGC-SRRRGDQRIRHSISDLEYPHPDDIRRMGEN 368 AD+HG + L A+GD A+ K V ++E C + G RHSI+DLE DD+++MG+ Sbjct: 302 IADNHGFRFSLHAQGDGAVSKTVSLMEKCQTDINGKLLNRHSITDLELTEKDDLKKMGDL 361 Query: 369 GIFAEVYAQILLL--NPSYEEAYMSAVAGKENESRFYNYKSMLEANVPVTIGTDLPLFLT 426 GI AE+Y QI L NP + + G ++N K M+ N+ ++ GTDLPL Sbjct: 362 GIIAEIYPQITSLYDNPLAKVKQIKEYVGPR-AKYYWNRKEMINNNIILSCGTDLPLLYD 420 Query: 427 SVPDSLYAASFRLFSDGSPMGGWQPEQGMPAAEVLKAWTINGARHNGMEERTGTLEAGKA 486 +P+S++ A F+D S + + +E++ AWT GA + G+E++ GTLEAGK Sbjct: 421 DIPESIFNACGGYFTDDSFQ--FNSNNCLNVSELIDAWTSGGAYNLGLEDKIGTLEAGKL 478 Query: 487 ADIAVFDRNLLDTTATEIRDAHVILTITAGQITY 520 ADI ++ +L ++ A V+ TI G+I + Sbjct: 479 ADIVIYSDDLFSIPIKNVKQAKVVTTIYDGKIVF 512 >Q3XZ05.1 Q3XZ05_ENTFC Similar to metal-dependent hydrolase with the TIM-barrel fold Length = 413 Score = 231 bits (588), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 135/388 (34%), Positives = 211/388 (54%), Gaps = 12/388 (3%) Query: 11 RVLLSNAVFTGIEDSVSPAFVALQGERIAAVGNPAEAKDWIGPKTFVHHLKDALIMPGVH 70 ++L S +F G E ++ + I V N D + T + D +MP +H Sbjct: 3 QILRSKMIFDG-EQPPFKGYIVINEGIIEKVENNWNYSDLLNENTELIAYDDQFVMPAIH 61 Query: 71 DNHVFFTGYMSMHRGVDLTHAATIDEALQLLRQDAENRPSEQNVYAYGWSEEGWGQLPGQ 130 DNHVFF+GY++M+ G+DL+ ++ +EA++ ++ ++ +++ +YA+GW W P + Sbjct: 62 DNHVFFSGYLAMNAGIDLSDTSSANEAVERIKAVMNHKKADEPIYAHGWDAALWKTDPSE 121 Query: 131 SLLDEAFPDRAVIAINRTKSYCWMNTLAQHKYQFAPDECSAESRAHLLKDMMQDRELVRQ 190 LL+E + AI++ +S+CWMN +A+ Y F E SAESR L+K+M+ +++L+ + Sbjct: 122 ELLNEINHFGPITAIDKNRSHCWMNAIAKQTYGFTEKETSAESRVLLIKEMLANKKLLAE 181 Query: 191 EFLDFARMLAKRGVTSIKDIGFDRHSXXXXXXXXXXXXXXXXXRVHFALEPVLQPLDIPA 250 + +F +L +GV S+K+I FD + ++ V +PL Sbjct: 182 VYAEFEALLLSKGVISMKEIVFDDAEFLSNIPQRKILS-------NLYVQAVQEPLQHEL 234 Query: 251 GLQYKERYQGEFLRFQGYKLMLDGVVADHTGDMLEPYADMPGVTTLRPVDYEAIETAVQA 310 +YKE+ E +RF G K+M+DGVVAD +GD+ Y GV + +DYEAI+ V A Sbjct: 235 LYEYKEKVFPEKVRFGGVKIMVDGVVADRSGDIYGVYQS--GVASPE-IDYEAIKAEVAA 291 Query: 311 ADSHGIKCCLTAEGDAAIRKAVDILEGCSRRRGDQRIRHSISDLEYPHPDDIRRMGENGI 370 + I CCLT EGD A KA IL +R + + +SISDLE +M E + Sbjct: 292 FNEVEIPCCLTTEGDKAGYKAASILVEFGKRL-PEGVFNSISDLEMVTQKTAEKMNEGQV 350 Query: 371 FAEVYAQILLLNPSYEEAYMSAVAGKEN 398 AEVY QIL LN + EEAYMS V E+ Sbjct: 351 VAEVYPQILGLNQTLEEAYMSTVIKNES 378 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.135 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,031,427,613 Number of extensions: 125829019 Number of successful extensions: 285615 Number of sequences better than 1.0e-05: 746 Number of HSP's gapped: 284754 Number of HSP's successfully gapped: 795 Length of query: 527 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 386 Effective length of database: 1,732,333,088 Effective search space: 668680571968 Effective search space used: 668680571968 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)