BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0472.0054.p (337 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A6WG36.1 A6WG36_KINRD Alpha/beta hydrolase fold 244 7e-63 B0YJE8.1 B0YJE8_PAEPO Alpa/beta hydrolase-thioesterase 226 3e-57 B4WUK0.1 B4WUK0_9SYNE Hydrolase, alpha/beta fold family, putative 164 1e-38 Q022C4.1 Q022C4_SOLUE Alpha/beta hydrolase fold 163 2e-38 A8YHH3.1 A8YHH3_MICAE Similar to tr|Q7NL16|Q7NL16 160 1e-37 >A6WG36.1 A6WG36_KINRD Alpha/beta hydrolase fold Length = 333 Score = 244 bits (624), Expect = 7e-63, Method: Compositional matrix adjust. Identities = 132/303 (43%), Positives = 188/303 (62%), Gaps = 3/303 (0%) Query: 37 EAIASNAAKKQYPAPGKLVDAGGFKLHIHKQGTG---SPTIILESGSGETSLSWRDIPDQ 93 E +A + PA VDAG LH+ ++G+G +PT++LE+GSGETS S+ + D Sbjct: 25 EEVARRTGRPPAPAGSLRVDAGSAVLHLVRRGSGAPGTPTVVLEAGSGETSASFARVLDG 84 Query: 94 LAKSATVVSYDRAGYAWSESSPNERTGANIVRELHNALMNEGLPGPYLVVGHSLGGMYAR 153 A VV+ DRAGY S S RTG ++V EL AL G P PY++ GHS+GG++AR Sbjct: 85 WDLPAAVVATDRAGYGRSGPSSAPRTGEHVVTELRTALRRSGSPPPYVLAGHSMGGLFAR 144 Query: 154 LFTQTYRDDVMGLVLVDARPENDERETAAILKAEKFAGNPSAAILAILKRSGVMRLFQDS 213 F + +V GLVL+DARPE+D R TA +L+A FA +P +LA L R+G +R Sbjct: 145 RFAVEHPGEVAGLVLLDARPEDDARRTADLLRAAGFAEDPPWPLLAGLARTGALRTLAPV 204 Query: 214 LLEGMVAKEDRGKFINVISTPSYFTAKEQEGKLATSTEDAIRGQNFGALPVRIIARGLPQ 273 LL V DR +F++V + P+YF + +E T+TED +RG+ G PV ++ARG Q Sbjct: 205 LLGPSVPAADRAEFLDVTAGPAYFRTRAEEAAAITATEDLVRGRTLGDRPVAVVARGRAQ 264 Query: 274 DYASFGFSEAGGKQLEAIWQAGQRSMLQLSTDSKLTIAEKSGHMIIHDQPELVIETILSL 333 DYA+ G A G+ LE +WQ GQR ML+LST S+LT+A SGH++ ++P+ V E + + Sbjct: 265 DYAAAGLDAATGRALEELWQDGQRRMLRLSTRSRLTVAAGSGHLVPRERPDAVREAVRWV 324 Query: 334 LKQ 336 L + Sbjct: 325 LTE 327 >B0YJE8.1 B0YJE8_PAEPO Alpa/beta hydrolase-thioesterase Length = 207 Score = 226 bits (575), Expect = 3e-57, Method: Compositional matrix adjust. Identities = 121/201 (60%), Positives = 144/201 (71%) Query: 9 KSSKRIWKKXXXXXXXXXXXXXGSGFLYEAIASNAAKKQYPAPGKLVDAGGFKLHIHKQG 68 K +R W + SGF+YE IAS K QYP PG+LVDAGG++LHI K G Sbjct: 2 KQRRRTWTRIVFLIISCLLLFVISGFVYEWIASKKDKSQYPPPGELVDAGGYRLHIRKLG 61 Query: 69 TGSPTIILESGSGETSLSWRDIPDQLAKSATVVSYDRAGYAWSESSPNERTGANIVRELH 128 GSPTI+LESGSGE+SLSWRDIP++L+ ATVVSYDRAGYAWSE + RTG NIV+ELH Sbjct: 62 NGSPTILLESGSGESSLSWRDIPEKLSSFATVVSYDRAGYAWSEEAATPRTGENIVQELH 121 Query: 129 NALMNEGLPGPYLVVGHSLGGMYARLFTQTYRDDVMGLVLVDARPENDERETAAILKAEK 188 AL N G+ PY++VGHSLGGMY+RL+ QTYRD+V GLVLVDARPEND R T I E+ Sbjct: 122 VALKNAGIQAPYILVGHSLGGMYSRLYAQTYRDEVAGLVLVDARPENDARRTNKIYAKER 181 Query: 189 FAGNPSAAILAILKRSGVMRL 209 NPS I +L++SG RL Sbjct: 182 PKVNPSPLISILLEKSGAFRL 202 >B4WUK0.1 B4WUK0_9SYNE Hydrolase, alpha/beta fold family, putative Length = 322 Score = 164 bits (415), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 102/316 (32%), Positives = 168/316 (53%), Gaps = 24/316 (7%) Query: 32 SGFLYEAIASNAAKKQYPAPGKLVDAGGFKLHIHKQGTGSPTIILESGSGETSLSWRDIP 91 +G LY+ +++ +++YP G+L+D GGF+LH++ G G+PT+++++G S++W +P Sbjct: 13 TGILYQVVSTAIDQRRYPPQGELIDIGGFRLHLNCMGQGTPTVVMDAGGCAPSIAWGLVP 72 Query: 92 DQLAKSATVVSYDRAGYAWSESSPN---ERTGANIVRELHNALMNEGLPGPYLVVGHSLG 148 ++AK A V YDRAG+ WSE PN RT ELH L + PY++VGHSLG Sbjct: 73 SEIAKFARVCIYDRAGFGWSE--PNFSAARTSQQSADELHLLLSKAEIEPPYILVGHSLG 130 Query: 149 GMYARLFTQTYRDDVMGLVLVDARPEN---DERETAAILKAEKFAGNPSAAILAILKRSG 205 G+ RL+ + +D+ GLVLVD+ EN E E + + + G + +L+ G Sbjct: 131 GVNMRLYASQHLEDIAGLVLVDSSHENQMTSEMERRIKMTSWLYQGFRIVSQFGLLRLIG 190 Query: 206 VMRLF-------QDSLLEGMVAKEDRGKFINVISTPSYFTAKEQEGKLATSTEDAIRG-Q 257 M L Q++ + + F + P Y+ A E + + IR Sbjct: 191 EMNLLPVLKEIKQETQNYPLAVQSLFDTFKSFCYRPDYWAAASSELANIKESLEGIRSVS 250 Query: 258 NFGALPVRIIARGLPQDYASFGFSEAGGKQLEAIWQAGQRSMLQLSTDSKLTIAEKSGHM 317 + G+LP+ ++++G +D S +++E W A Q + LS+ S+ IAE SGH+ Sbjct: 251 SLGSLPLIVLSQG-SKD------STVSAERVER-WAALQLDLTNLSSCSQHVIAEDSGHL 302 Query: 318 IIHDQPELVIETILSL 333 I DQPEL++ + L Sbjct: 303 IPLDQPELIVSAVRQL 318 >Q022C4.1 Q022C4_SOLUE Alpha/beta hydrolase fold Length = 334 Score = 163 bits (413), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 107/301 (35%), Positives = 154/301 (51%), Gaps = 4/301 (1%) Query: 33 GFLYEAIASNAAKKQYPAPGKLVDAGGFKLHIHKQGTGSPTIILESGSGETSLSWRDIPD 92 GF+Y+ +A + P PG+LVD GG +L++ G GSPT++L+S G S SW I Sbjct: 25 GFVYQRVAERYERGNLPRPGRLVDVGGHRLYLSCTGEGSPTVVLDSALGVVSYSWTPIQA 84 Query: 93 QLAKSATVVSYDRAGYAWSESSPNERTGANIVRELHNALMNEGLPGPYLVVGHSLGGMYA 152 ++++ V SYDRAGY S+ P RT + ELH+ L GPY++VGHSLGG+ Sbjct: 85 EVSRFTRVCSYDRAGYGLSDPGPLPRTSKQLASELHSLLGTAEEAGPYVLVGHSLGGLTI 144 Query: 153 RLFTQTYRDDVMGLVLVDARPENDERETAAILKAEKFAGNPSAAILAILKRSGVMRLFQD 212 RLFTQ + +V GLVLVD+ EN E L+ +L G+ R+ Sbjct: 145 RLFTQAHPAEVAGLVLVDSASENAEAHLTPELRPLMMPPLTQMKFAGVLAEFGMHRIVL- 203 Query: 213 SLLEGMVAKE-DRGKFINVISTPSYFTAKEQEGKLATSTEDAIRGQNFGALPVRIIARG- 270 S+ +G + E R +N+ A + L STE G P+ ++ RG Sbjct: 204 SMRKGRGSTEAQRAAALNLRRRAYIQAAIGELEALPLSTEQVRSAGKLGDRPLIVLTRGP 263 Query: 271 LPQDYASFGFSEAGGKQLEAIWQAG-QRSMLQLSTDSKLTIAEKSGHMIIHDQPELVIET 329 + A G S A + E IW+ Q +M+ LST + A+ SGHMI ++PE VI+ Sbjct: 264 VHPGEAPRGVSPAIYENFERIWRTEIQATMVGLSTRGEQRFAKHSGHMIPQEEPEAVIDG 323 Query: 330 I 330 I Sbjct: 324 I 324 >A8YHH3.1 A8YHH3_MICAE Similar to tr|Q7NL16|Q7NL16 Length = 336 Score = 160 bits (406), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 113/314 (35%), Positives = 157/314 (50%), Gaps = 25/314 (7%) Query: 36 YEAIASNAAKKQYPAPGKLVDAGGFKLHIHKQGTGSPTIILESGSGETSLSWRDIPDQLA 95 Y+ +A+ +YP PG+L+D GG++LH+H + GSPT++++ G G S W + ++A Sbjct: 24 YQQVATIKDLSKYPPPGQLIDVGGYRLHLHCKSQGSPTVVMDYGLGGISPLWHWVQSEVA 83 Query: 96 KSATVVSYDRAGYAWSESSPNERTGANIVRELHNALMNEGLPGPYLVVGHSLGGMYARLF 155 K +V YDRAGY WSE SP+ RT +V+ELH L G+ GPYL+VGHSLGG+ RLF Sbjct: 84 KFTSVCVYDRAGYGWSEPSPHPRTSLIMVQELHTLLTKGGIAGPYLLVGHSLGGLNMRLF 143 Query: 156 TQTYRDDVMGLVLVDARPENDERETAAILKAEKFAGNPSAAILAILKR------------ 203 Y +V+G+VLVDA P N + A L+I+ R Sbjct: 144 ASRYPSEVVGVVLVDAVPANVYSRLGNEFRKNMAATRQMFRSLSIISRLGILRLLLQLKG 203 Query: 204 SGVMRLFQDSLLEGMVAKEDRGKFINVISTPSYFTAKEQEGKLATSTEDAIRGQNFGA-L 262 S V F L V KF+ P F E L + +F + L Sbjct: 204 SDVAPEFVQKLPPS-VQSVVLAKFL-----PQSFNTALAESALMKKDAALVSKTSFPSHL 257 Query: 263 PVRIIARGLPQDYASFGFSEAGGKQLEAIWQAGQRSMLQLSTDSKLTIAEKSGHMIIHDQ 322 P+ +I+ GL FS + E+IW+ Q LST L IA SGH I DQ Sbjct: 258 PLVVISHGLNM------FSGQNVEVSESIWRQLQAETSDLSTSGSLQIAHSSGHNIHIDQ 311 Query: 323 PELVIETILSLLKQ 336 PELV++ I +L+Q Sbjct: 312 PELVVDAIRKILQQ 325 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.314 0.131 0.371 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,925,447,543 Number of extensions: 80537101 Number of successful extensions: 158167 Number of sequences better than 1.0e-05: 533 Number of HSP's gapped: 158766 Number of HSP's successfully gapped: 535 Length of query: 337 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 201 Effective length of database: 1,779,438,163 Effective search space: 357667070763 Effective search space used: 357667070763 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (22.0 bits) S2: 131 (55.1 bits)