BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0472.0053.p (239 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K4I6.1 B3K4I6_9BACI Beta-lactamase domain protein 301 3e-80 B7JEG0.1 B7JEG0_BACC0 Metallo-beta-lactamase family protein 288 4e-76 C2TNS9.1 C2TNS9_BACCE Beta-lactamase domain protein 288 4e-76 B3ZBV6.1 B3ZBV6_BACCE Metallo-beta-lactamase family protein 287 6e-76 Q4MR27.1 Q4MR27_BACCE Metal-dependent hydrolase 286 1e-75 >B3K4I6.1 B3K4I6_9BACI Beta-lactamase domain protein Length = 239 Score = 301 bits (771), Expect = 3e-80, Method: Compositional matrix adjust. Identities = 148/236 (62%), Positives = 181/236 (76%), Gaps = 1/236 (0%) Query: 1 MRLTQEGQLLQLTWLPRLFPVNCYLVEEKEGLTLIDAAMSFSVQGILDTAAKLNKPINRI 60 +R T E Q+ Q+++LPRLFP+N YLVEE +G +LIDA MSFS +GIL AA + KPI RI Sbjct: 2 LRTTIE-QVTQISFLPRLFPINVYLVEESDGFSLIDAGMSFSQKGILQAAADIGKPIKRI 60 Query: 61 ILTHAHGDHVGALDELKQRLPSAQVYISERDAALLRGDRSLREGEPQTPIKGSVPTKITT 120 +LTHAHGDHVGALD LK+ LP+A V IS RDA LL+G+ L+ GEPQTPI+G +P ITT Sbjct: 61 VLTHAHGDHVGALDGLKKELPNASVCISRRDALLLKGNAELQPGEPQTPIRGDIPKNITT 120 Query: 121 VPDILLQEGDAVGSLTAIATPGHTPGSMSFLDERTGALIAGDALQTFRRTAVAGTVVPFF 180 VPD+LL++GD++GSL AIATPGHTPG M+FLDER+G LIAGDA QT AV+G + P+F Sbjct: 121 VPDVLLEDGDSIGSLKAIATPGHTPGHMAFLDERSGILIAGDAWQTRGGLAVSGVIKPWF 180 Query: 181 PFPAMATWNKASALESAVKLLKLSPKVLAVGHGNLLHAPIEHMKYAVEQAEQLQKK 236 PFPAMATW+K ALESA L L P VLAVGHG +L P M+ AV QAE ++ Sbjct: 181 PFPAMATWSKEQALESAGMLASLKPAVLAVGHGRMLRNPAGAMQEAVAQAESTFRR 236 >B7JEG0.1 B7JEG0_BACC0 Metallo-beta-lactamase family protein Length = 240 Score = 288 bits (736), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 139/232 (59%), Positives = 176/232 (75%) Query: 1 MRLTQEGQLLQLTWLPRLFPVNCYLVEEKEGLTLIDAAMSFSVQGILDTAAKLNKPINRI 60 MR+ E + QL++LPR+FPVNCY VEE++GLTLIDAA+ +S +GIL A K+ KPI I Sbjct: 1 MRMMHEKTVYQLSFLPRVFPVNCYFVEEEDGLTLIDAALPYSAKGILQAAEKIGKPITNI 60 Query: 61 ILTHAHGDHVGALDELKQRLPSAQVYISERDAALLRGDRSLREGEPQTPIKGSVPTKITT 120 +LTHAH DH+GALD LK+ LP VYIS+RDA LL GD +L++ EP TPIKG VP KI T Sbjct: 61 VLTHAHDDHIGALDTLKEVLPHVPVYISKRDAKLLEGDTTLQKDEPNTPIKGGVPKKIKT 120 Query: 121 VPDILLQEGDAVGSLTAIATPGHTPGSMSFLDERTGALIAGDALQTFRRTAVAGTVVPFF 180 VPDILL++GD VGSL AI TPGHTPGSMSFLD R ALI GDA QT TAV+G + +F Sbjct: 121 VPDILLEDGDRVGSLLAIMTPGHTPGSMSFLDIRNNALIVGDAFQTRGGTAVSGQMKFWF 180 Query: 181 PFPAMATWNKASALESAVKLLKLSPKVLAVGHGNLLHAPIEHMKYAVEQAEQ 232 PFPAMATW+K AL+SA KL + P +LA GHG +++ P ++ A+++A++ Sbjct: 181 PFPAMATWSKEMALQSAEKLREYEPSLLAAGHGKMVNDPGAIIELAIQEAKR 232 >C2TNS9.1 C2TNS9_BACCE Beta-lactamase domain protein Length = 240 Score = 288 bits (736), Expect = 4e-76, Method: Compositional matrix adjust. Identities = 139/232 (59%), Positives = 176/232 (75%) Query: 1 MRLTQEGQLLQLTWLPRLFPVNCYLVEEKEGLTLIDAAMSFSVQGILDTAAKLNKPINRI 60 MR+ E + QL++LPR+FPVNCY VEE++GLTLIDAA+ +S +GIL A K+ KPI I Sbjct: 1 MRMMHEKTVYQLSFLPRVFPVNCYFVEEEDGLTLIDAALPYSAKGILQAAEKIGKPITNI 60 Query: 61 ILTHAHGDHVGALDELKQRLPSAQVYISERDAALLRGDRSLREGEPQTPIKGSVPTKITT 120 +LTHAH DH+GALD LK+ LP VYIS+RDA LL GD +L++ EP TPIKG VP KI T Sbjct: 61 VLTHAHDDHIGALDTLKEVLPHVPVYISKRDAKLLEGDTTLQKDEPNTPIKGGVPKKIKT 120 Query: 121 VPDILLQEGDAVGSLTAIATPGHTPGSMSFLDERTGALIAGDALQTFRRTAVAGTVVPFF 180 VPDILL++GD VGSL AI TPGHTPGSMSFLD R ALI GDA QT TAV+G + +F Sbjct: 121 VPDILLEDGDRVGSLLAIMTPGHTPGSMSFLDIRNNALIVGDAFQTRGGTAVSGQMKFWF 180 Query: 181 PFPAMATWNKASALESAVKLLKLSPKVLAVGHGNLLHAPIEHMKYAVEQAEQ 232 PFPAMATW+K AL+SA KL + P +LA GHG +++ P ++ A+++A++ Sbjct: 181 PFPAMATWSKEMALQSAEKLREYEPSLLAAGHGKMVNDPGAIIELAIQEAKR 232 >B3ZBV6.1 B3ZBV6_BACCE Metallo-beta-lactamase family protein Length = 240 Score = 287 bits (734), Expect = 6e-76, Method: Compositional matrix adjust. Identities = 138/232 (59%), Positives = 176/232 (75%) Query: 1 MRLTQEGQLLQLTWLPRLFPVNCYLVEEKEGLTLIDAAMSFSVQGILDTAAKLNKPINRI 60 MR+ E + QL++LPR+FPVNCY VEE++GLTLIDAA+ +S +GIL A K+ KPI I Sbjct: 1 MRMMHEKTVYQLSFLPRVFPVNCYFVEEEDGLTLIDAALPYSAKGILQAAEKIGKPITNI 60 Query: 61 ILTHAHGDHVGALDELKQRLPSAQVYISERDAALLRGDRSLREGEPQTPIKGSVPTKITT 120 +LTHAH DH+GALD LK+ LP VYIS+RDA LL GD +L++ EP TPIKG VP KI T Sbjct: 61 VLTHAHDDHIGALDTLKEVLPHVPVYISKRDAKLLEGDTTLQKDEPNTPIKGGVPKKIKT 120 Query: 121 VPDILLQEGDAVGSLTAIATPGHTPGSMSFLDERTGALIAGDALQTFRRTAVAGTVVPFF 180 VPDILL++GD VGSL AI TPGHTPGSMSFLD R ALI GDA QT TAV+G + +F Sbjct: 121 VPDILLEDGDRVGSLLAIMTPGHTPGSMSFLDIRNNALIVGDAFQTRGGTAVSGQMKFWF 180 Query: 181 PFPAMATWNKASALESAVKLLKLSPKVLAVGHGNLLHAPIEHMKYAVEQAEQ 232 PFPAMATW+K +L+SA KL + P +LA GHG +++ P ++ A+++A++ Sbjct: 181 PFPAMATWSKEISLQSAEKLREYEPSLLAAGHGKMINDPEAVIELAIQEAKR 232 >Q4MR27.1 Q4MR27_BACCE Metal-dependent hydrolase Length = 240 Score = 286 bits (732), Expect = 1e-75, Method: Compositional matrix adjust. Identities = 137/232 (59%), Positives = 177/232 (76%) Query: 1 MRLTQEGQLLQLTWLPRLFPVNCYLVEEKEGLTLIDAAMSFSVQGILDTAAKLNKPINRI 60 MR+ E + QL++LPR+FPVNCY VEE++GLTLIDAA+ +S +GIL +A K+ KPI +I Sbjct: 1 MRMMHEQTVYQLSFLPRVFPVNCYFVEEEDGLTLIDAALPYSAKGILQSAEKIGKPITKI 60 Query: 61 ILTHAHGDHVGALDELKQRLPSAQVYISERDAALLRGDRSLREGEPQTPIKGSVPTKITT 120 +LTHAH DH+GALD LK+ LP VYIS+RDA LL GD +L++ EP TPIKG VP KI T Sbjct: 61 VLTHAHDDHIGALDALKEVLPHVPVYISKRDAKLLEGDTTLQKDEPNTPIKGGVPKKIKT 120 Query: 121 VPDILLQEGDAVGSLTAIATPGHTPGSMSFLDERTGALIAGDALQTFRRTAVAGTVVPFF 180 VPD+LL++GD VGSL AI TPGHTPGSMSFLD R ALI GDA QT AV+G + +F Sbjct: 121 VPDVLLEDGDRVGSLLAIMTPGHTPGSMSFLDVRNKALIVGDAFQTRGGMAVSGQMKFWF 180 Query: 181 PFPAMATWNKASALESAVKLLKLSPKVLAVGHGNLLHAPIEHMKYAVEQAEQ 232 PFPAMATW+K AL+SA KL + P +LA GHG +++ P ++ A+++A++ Sbjct: 181 PFPAMATWSKEVALQSAEKLREYEPSLLAAGHGKMINDPGAVIELAIKEAKR 232 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,373,396,995 Number of extensions: 54094336 Number of successful extensions: 162056 Number of sequences better than 1.0e-05: 895 Number of HSP's gapped: 162512 Number of HSP's successfully gapped: 895 Length of query: 239 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 107 Effective length of database: 1,817,122,223 Effective search space: 194432077861 Effective search space used: 194432077861 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)