BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0472.0028.p (402 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B1DCZ8.1 B1DCZ8_9BACL Two component transcriptional regulator, A... 447 e-123 B7GJK9.1 B7GJK9_ANOFW DNA-binding response regulator (Contains R... 157 1e-36 B3EYL7.1 B3EYL7_BACST Two-component response regulator 155 7e-36 Q5KYP0.1 Q5KYP0_GEOKA Two-component response regulator 155 9e-36 B4BMA7.1 B4BMA7_9BACI Two component transcriptional regulator, A... 145 5e-33 >B1DCZ8.1 B1DCZ8_9BACL Two component transcriptional regulator, AraC family Length = 395 Score = 447 bits (1149), Expect = e-123, Method: Compositional matrix adjust. Identities = 212/392 (54%), Positives = 290/392 (73%), Gaps = 3/392 (0%) Query: 1 VNILVADDERVIREGIRRTIGQISPDHQVFVAAKAEEAVRIMEEQRIHIVLTDILMPGMS 60 +NIL+ DDE VIREGI+RT+ P + ++A AEEAV + + RI IVLTDILMPGM+ Sbjct: 1 MNILIVDDENVIREGIKRTLNNRFPAYSTYLAVNAEEAVAQLRKHRIDIVLTDILMPGMT 60 Query: 61 GLEFMKISKRRYPYVKWVVISAHSEFSYAQEAVRLGARDYLLKPIGKNKLLELINNLTAE 120 GLE M +++ YP VKWVVISA+SEFSYAQEAVRLGA+DYLLKPIGK L E+I + E Sbjct: 61 GLEMMNLTRSMYPRVKWVVISAYSEFSYAQEAVRLGAKDYLLKPIGKEVLAEMIEKICGE 120 Query: 121 IEQDNDISRQGERLKASLRFLREGVFQRLASGLDIGNLDIEPFIEDYKHFYMVMVQLDAE 180 IEQ+ +++ + E LK + +LRE VFQR A GLDIG D+ PF++ + HF ++MV++++ Sbjct: 121 IEQEREMTEEAELLKLNRNYLREAVFQRWAQGLDIGRFDMMPFMDSHPHFNLIMVKMES- 179 Query: 181 DRSIRLEHFIVENVLSELIELHGRGFVVSYDRQSLLGLITLREDAAIQQFQSEVKEHLTH 240 D+ ++LEHF++ENVL ELIE +G+GFV YD +SLLGL+TL E I E++ HL Sbjct: 180 DKVVQLEHFMIENVLGELIEKYGQGFVTIYDSKSLLGLVTLPESGTITSLLEELRTHLIK 239 Query: 241 YLKIPFQVIHSGLSHDFSTVPQVVKRMREASASQVLELEPMKGSGEKAIDVALHYIKEHF 300 YL++PFQ++H+ D VP V+RMR+AS++QV E +++I+VAL YI+ H+ Sbjct: 240 YLRVPFQIMHTDRIEDIDAVPGEVQRMRQASSTQV--YEHYASGSDQSIEVALQYIRTHY 297 Query: 301 YEDLSLEKMASVVFLNPAYFSQLFKQKTGQGYKEYVTSLRLEQAKXXXXXXXXXXAEIAE 360 + DLSLEK+A++V+LNP YFSQLFKQKTG G+KEYV LRLEQAK A++AE Sbjct: 298 HADLSLEKVAAIVYLNPVYFSQLFKQKTGSGFKEYVIGLRLEQAKQMLLNPKLKLADVAE 357 Query: 361 RVGYQDMKHFTQMFRKRYQLTPTEYRQQQNIN 392 R+GYQDM+HF+Q+FRK+Y TP+E+RQ+ ++ Sbjct: 358 RIGYQDMRHFSQLFRKKYGETPSEFRQRHRMD 389 >B7GJK9.1 B7GJK9_ANOFW DNA-binding response regulator (Contains REC and AraC-type DNA-binding domain) Length = 428 Score = 157 bits (398), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 113/406 (27%), Positives = 214/406 (52%), Gaps = 24/406 (5%) Query: 2 NILVADDERVIREGIRRTIGQISP-DHQVFVAAKAEEAVRIMEEQRIHIVLTDILMPGMS 60 +L+ADDE + REG++ I + P +F A A++ +E+ R HI+ D+ MPG+ Sbjct: 21 KLLIADDEPLEREGLQLMIERAFPHTFTIFHAEHGRSAIQQVEQHRPHIIFMDMKMPGIQ 80 Query: 61 GLEFMKISKRRYPYVKWVVISAHSEFSYAQEAVRLGARDYLLKPIGKNKLLELINNLTAE 120 GLE + ++ K V+++A+ F+YA+EA+ G +Y+LKP K ++++L+ L + Sbjct: 81 GLEAIAEIRKMDAQAKIVILTAYDYFTYAKEAISFGVSEYVLKPAKKQQMIDLLQKLLQQ 140 Query: 121 IEQDNDISRQGERLKASLRFLREGVFQRLASGLDIGNLD---IEPFIE-DYKHFYMVMVQ 176 I ++ + Q + L L + + + + L +G +D F +++ Y ++V+ Sbjct: 141 IAEEQAMREQQLATREKLVQL-QALGEMAWTWLFMGKMDECAAHTFTGMEFESGYAIVVE 199 Query: 177 LDAEDRSIRLEHFIVENVLSELIELHGRGFVVSYDRQSLLGLITLRED----AAIQQFQS 232 L+ D R + E + + I+ R +++ + I ++D + +Q Sbjct: 200 LEKADACEREKW---EEKMKQCIKQQRRCLCSLLNQRQMAIFIEAKQDEHVISFVQSLLK 256 Query: 233 EVKEHLTHYLKIPFQVIHSGLSHDFSTVPQVVKRMREASA-SQVLELE--PMKG------ 283 ++++ L +KI I SG+ + + +R S+ S+V+ ++ P+ Sbjct: 257 QLEKVLQQRVKIGIGTIQSGVDGMKRSYKEASIAVRYVSSFSRVMHVDDVPLTDEVEQTT 316 Query: 284 --SGEKAIDVALHYIKEHFYEDLSLEKMASVVFLNPAYFSQLFKQKTGQGYKEYVTSLRL 341 +G I+ +++E++ D++LE++A V L P YFS+LFK++TGQ + +YVT LR+ Sbjct: 317 IKTGGSVIEQVEMFLQENYCYDVTLEEVAKYVHLTPYYFSKLFKKETGQTFIDYVTHLRI 376 Query: 342 EQAKXXXXXXXXXXAEIAERVGYQDMKHFTQMFRKRYQLTPTEYRQ 387 E+AK E RVGY+D +F+++F+K +TPTEYRQ Sbjct: 377 EKAKQLMRDEGLTVKEACYRVGYKDPNYFSRVFKKVTNMTPTEYRQ 422 >B3EYL7.1 B3EYL7_BACST Two-component response regulator Length = 404 Score = 155 bits (392), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 117/411 (28%), Positives = 201/411 (48%), Gaps = 35/411 (8%) Query: 2 NILVADDERVIREGIRRTIGQISPDHQVFVAAK-AEEAVRIMEEQRIHIVLTDILMPGMS 60 +L+ADDE +IREGIR +I + +V A+ EEA+ + R+ ++ D+ MP M Sbjct: 5 KVLIADDEAIIREGIRESIDWNEFNMEVVAEAEDGEEALELALRHRVDVLFVDLSMPIMD 64 Query: 61 GLEFMKISKRRYPYVKWVVISAHSEFSYAQEAVRLGARDYLLKPIGKNKLLELINNLTAE 120 GL MK ++ + P +VI+ + EFSYAQEA+RL DYLLKP +L E++ + + Sbjct: 65 GLTLMKYAREKLPNCHMIVITGYDEFSYAQEAIRLQVDDYLLKPTDPQRLREVVAKVKEK 124 Query: 121 IEQDNDISRQGERLKASL---------RFLREGVFQRLASGLDIGNLDIEPFIEDYK--- 168 +EQ+ + E L + +F E V RL +G L + Sbjct: 125 LEQEQKEKQYRELLTNQVQKHIHVLRQQFGMEWVAGRLTEEDIMGQLSLLGLSRSCPAQV 184 Query: 169 ---HFYMVMVQLDAEDRSIRLEHFIVENVLSELIELHGRG-FVVSYDRQSLLGLITLR-- 222 ++ Q DR +L F +E +SEL+ G G +V D + +I+ + Sbjct: 185 VVIQWFSFKNQPIVSDRDRQLLLFAIEKAVSELL---GDGEKIVFRDSNEFIVVISWKPI 241 Query: 223 EDAAIQQFQSEVKEHLTHYLKIPFQVIHSGLSHDFSTVPQVVKRMREASASQVLELEPMK 282 + +Q ++ +K+HL + + + G+ + + ++M E S L P+ Sbjct: 242 SEEQCRQMETALKQHLHIRASVYIETVEGGMVGVATAYEKCKEQMVEES-----RLSPI- 295 Query: 283 GSGEKAIDVALHYIKEHFYE-DLSLEKMASVVFLNPAYFSQLFKQKTGQGYKEYVTSLRL 341 + A YI++HF + DL+LE +A + ++P Y S++ KQ+ G + +T +R+ Sbjct: 296 ------VRRARQYIQKHFSQSDLTLESVAEFLNVSPVYLSRMIKQELGISFIHLLTKIRM 349 Query: 342 EQAKXXXXXXXXXXAEIAERVGYQDMKHFTQMFRKRYQLTPTEYRQQQNIN 392 E+A EIAERVGY +F+ F+K ++P +YR+ + I+ Sbjct: 350 EKAAELLLSTELPIHEIAERVGYDTQHYFSTAFKKAMGVSPNQYRRTRMIS 400 >Q5KYP0.1 Q5KYP0_GEOKA Two-component response regulator Length = 401 Score = 155 bits (391), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 116/411 (28%), Positives = 199/411 (48%), Gaps = 35/411 (8%) Query: 2 NILVADDERVIREGIRRTIGQISPDHQVFVAAK-AEEAVRIMEEQRIHIVLTDILMPGMS 60 +L+ADDE +IREGIR +I + +V A+ EEA+ + R++++ D+ MP M Sbjct: 3 KVLIADDEAIIREGIRESIDWNEFNMEVVAEAEDGEEALELALRHRVNVLFVDLSMPIMD 62 Query: 61 GLEFMKISKRRYPYVKWVVISAHSEFSYAQEAVRLGARDYLLKPIGKNKLLELINNLTAE 120 GL MK ++ + P +VI+ + EFSYAQEA+RL DYLLKP +L E++ + + Sbjct: 63 GLTLMKYAREKLPNCHMIVITGYDEFSYAQEAIRLQVDDYLLKPTDPQRLREVVAKVKEK 122 Query: 121 IEQDNDISRQGERLKASL---------RFLREGVFQRLASGLDIGNLDIEPFIEDYK--- 168 +EQ+ + E L + +F E V RL +G L + Sbjct: 123 LEQEQKEKQYRELLTNQVQKHIHVLRQQFGMEWVAGRLTEEDIMGQLSLLGLSRSCPAQV 182 Query: 169 ---HFYMVMVQLDAEDRSIRLEHFIVENVLSELIELHGRG-FVVSYDRQSLLGLITLR-- 222 ++ Q DR +L F +E +SEL+ G G +V D + +I+ + Sbjct: 183 VVIQWFSFKNQPIVSDRDRQLLLFAIEKAVSELL---GDGEKIVFRDSNEFIVVISWKPI 239 Query: 223 EDAAIQQFQSEVKEHLTHYLKIPFQVIHSGLSHDFSTVPQVVKRMREASASQVLELEPMK 282 + +Q ++ +K+HL + + + G++ + + ++M E S L P+ Sbjct: 240 SEEQCRQMETALKQHLHIRASVYIETVEGGMTGVMAAYEKCKEQMVEES-----RLSPI- 293 Query: 283 GSGEKAIDVALHYIKEHFYE-DLSLEKMASVVFLNPAYFSQLFKQKTGQGYKEYVTSLRL 341 + A YI++HF + DL+LE +A + ++P Y S++ KQ+ G + + R+ Sbjct: 294 ------VRRARQYIQKHFSQSDLTLESVAQFLNVSPVYLSRIIKQELGISFIHLLAKTRM 347 Query: 342 EQAKXXXXXXXXXXAEIAERVGYQDMKHFTQMFRKRYQLTPTEYRQQQNIN 392 E+A EIAERVGY +F+ F+K ++P +YR+ N Sbjct: 348 EKAAELLLSTELPIHEIAERVGYDTQHYFSTAFKKAMGVSPNQYRRMHITN 398 >B4BMA7.1 B4BMA7_9BACI Two component transcriptional regulator, AraC family Length = 400 Score = 145 bits (367), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 115/411 (27%), Positives = 203/411 (49%), Gaps = 45/411 (10%) Query: 2 NILVADDERVIREGIRRTIGQISPDHQVFVAAK-AEEAVRIMEEQRIHIVLTDILMPGMS 60 +L+ADDE +IREGIR +I + +V A+ EEA+ + + +H++ D+ MP M Sbjct: 3 KVLIADDEMIIREGIRESIDWAQFNMEVIAEAEDGEEALELAIKHEVHVLFVDLSMPIMD 62 Query: 61 GLEFMKISKRRYPYVKWVVISAHSEFSYAQEAVRLGARDYLLKPIGKNKLLELINNLTAE 120 GL MK + R P+ +VI+ + EFSYAQEA+RL DYLLKP +L E++ + + Sbjct: 63 GLTLMKHVRERLPHCHMIVITGYDEFSYAQEALRLQVDDYLLKPTDPKQLREVVAKVKEK 122 Query: 121 IEQDND----ISRQGERLKASLRFLREGVFQRLASGLDIGNLDIEPF--------IEDYK 168 +E+++ + +++ ++R LR Q+L G L E + + Sbjct: 123 LEREHQERGYVELLTSQVQKNVRLLR----QQLGVEWVEGRLTEEEMMRQLPLLGLPSFC 178 Query: 169 HFYMVMVQ---------LDAEDRSIRLEHFIVENVLSELIELHGRGFVVSYDRQSLLGLI 219 +V++Q ++ DR I L F +EN++SEL+ H +V D + +I Sbjct: 179 PVQVVVIQWFSFKNQPIMNDRDRHILL--FAIENIVSELLVNH--EMLVFRDSNGFVVVI 234 Query: 220 TLREDAAIQQ--FQSEVKEHLTHYLKIPFQVIHSGLSHDFSTVPQVVKRMREASASQVLE 277 + Q+ ++ +K++L +++ G++ S + ++M E Sbjct: 235 VWTPISEEQRRGIEAALKQYLYIGASAYMEMVEGGVTGVISAYEKCKRKMEEEK-----R 289 Query: 278 LEPMKGSGEKAIDVALHYIKEHFYE-DLSLEKMASVVFLNPAYFSQLFKQKTGQGYKEYV 336 L P+ + A YI+ HF + +L+LE +A + ++P Y S++ KQ+ G + + Sbjct: 290 LSPV-------VRRAKQYIQTHFSQSELTLESVAQFLNVSPIYLSRMIKQELGISFVHLL 342 Query: 337 TSLRLEQAKXXXXXXXXXXAEIAERVGYQDMKHFTQMFRKRYQLTPTEYRQ 387 T +RL +A EIAERVGY +F+ F+K + P +YR+ Sbjct: 343 TKIRLTKAVELLLSTELPIHEIAERVGYDTQHYFSTAFKKAMGVPPNQYRK 393 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.321 0.137 0.380 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,127,362,607 Number of extensions: 80615339 Number of successful extensions: 315023 Number of sequences better than 1.0e-05: 9802 Number of HSP's gapped: 328280 Number of HSP's successfully gapped: 10450 Length of query: 402 Length of database: 3,060,696,203 Length adjustment: 138 Effective length of query: 264 Effective length of database: 1,760,596,133 Effective search space: 464797379112 Effective search space used: 464797379112 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 132 (55.5 bits)