BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0471.0024.p (516 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KKS4.1 B3KKS4_9BACI Glucose-6-phosphate 1-dehydrogenase EC=1.1... 939 0.0 B1DF50.1 B1DF50_9BACL Glucose-6-phosphate 1-dehydrogenase EC=1.1... 811 0.0 B7GHJ3.1 B7GHJ3_ANOFW Glucose-6-phosphate 1-dehydrogenase EC=1.1... 624 e-177 C5D429.1 C5D429_9BACI Glucose-6-phosphate 1-dehydrogenase EC=1.1... 595 e-168 C2WFI6.1 C2WFI6_BACCE Glucose-6-phosphate 1-dehydrogenase 593 e-167 >B3KKS4.1 B3KKS4_9BACI Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 515 Score = 939 bits (2426), Expect = 0.0, Method: Compositional matrix adjust. Identities = 451/512 (88%), Positives = 469/512 (91%) Query: 1 MAENQTLDALHTPGAVFFIFGATGDLARRKLFPAIYSLYREGKLTHDFAVIGVARRPRTQ 60 MAENQ LD + TPGAVFFIFGATGDLARRKLFPAIYSLYREGKL DFAVIGVARRPRTQ Sbjct: 1 MAENQNLDTMKTPGAVFFIFGATGDLARRKLFPAIYSLYREGKLDEDFAVIGVARRPRTQ 60 Query: 61 EEFREDVKESIQEFCRYQAGDASEWNEFVQHFEYKSLDINNIEGFRELNAQTEALEEKFR 120 EEFREDV SIQEFCRY + SEWN F QHFEYKSLDINNI+GFREL QTE LE KF Sbjct: 61 EEFREDVYRSIQEFCRYSSEQDSEWNAFAQHFEYKSLDINNIDGFRELREQTEQLETKFN 120 Query: 121 IPGNRMFYLALAPELFGSVSFNLKAGGMLQTRGWNRLVIEKPFGYNLESAEQLNEQIRQV 180 IPGNR+FYLALAPELFGSVSFNL GGML GWNRLVIEKPFGY+LESA +LNE+IR+V Sbjct: 121 IPGNRLFYLALAPELFGSVSFNLMKGGMLDGEGWNRLVIEKPFGYDLESAAKLNEEIRKV 180 Query: 181 FKEEEIYRIDHYLGKEMVQNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYY 240 FKEEEIYRIDHYLGKEMVQNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYY Sbjct: 181 FKEEEIYRIDHYLGKEMVQNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYY 240 Query: 241 DHAGALRDMGQNHMLQLLTMIAMEPPSRLLAEDIRDEKVKVLRSLRPYASSGEVHENVVR 300 DHAGALRDMGQNHMLQLLTMIAMEPPSRLLAEDIRDEKVKVLRSLRPYAS+ EV NVVR Sbjct: 241 DHAGALRDMGQNHMLQLLTMIAMEPPSRLLAEDIRDEKVKVLRSLRPYASNEEVKNNVVR 300 Query: 301 GQYTQGLYKGKTLPAYRQEDKVDPESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKT 360 GQYT G GK LPAYR+EDKV+PESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKT Sbjct: 301 GQYTSGSAGGKDLPAYREEDKVNPESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKT 360 Query: 361 TEVVVEFKGMPTNVYLGQKHKLEPNLLVIRVNPMEGIYVKINAKKPGSESEIQPLAMDFC 420 TEVVVEFK MPTNVYLGQKH LEPNLLVIRVNPMEGIYVKINAKKPGSESEI P+AMDFC Sbjct: 361 TEVVVEFKRMPTNVYLGQKHSLEPNLLVIRVNPMEGIYVKINAKKPGSESEIAPVAMDFC 420 Query: 421 QSCMVGINSPEAYERLLHDAARGDSTYFTRWDEVSSAWSFVDRIAQAWREGTGDLASYPA 480 QSC+VGINSPEAYERLLHDAARGDSTYFTRWDEV+SAWSFVDRIA AWRE G+L SYPA Sbjct: 421 QSCIVGINSPEAYERLLHDAARGDSTYFTRWDEVASAWSFVDRIASAWRENQGELESYPA 480 Query: 481 GSWGPVEADQLLAREGFHWWPVNGQDEDNVVW 512 GSWGP +AD+LL +GFHWWPVNGQ EDNVVW Sbjct: 481 GSWGPDKADELLKEDGFHWWPVNGQLEDNVVW 512 >B1DF50.1 B1DF50_9BACL Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 514 Score = 811 bits (2096), Expect = 0.0, Method: Compositional matrix adjust. Identities = 371/511 (72%), Positives = 437/511 (85%) Query: 6 TLDALHTPGAVFFIFGATGDLARRKLFPAIYSLYREGKLTHDFAVIGVARRPRTQEEFRE 65 +++ + GA+++IFGATGDLA+RKLFPA++SLY+EGKL+ +FAV+G+ARR RT E+FR Sbjct: 2 NVESSNAQGAIYYIFGATGDLAKRKLFPALFSLYKEGKLSENFAVVGLARRERTNEQFRA 61 Query: 66 DVKESIQEFCRYQAGDASEWNEFVQHFEYKSLDINNIEGFRELNAQTEALEEKFRIPGNR 125 D+ ESI EFCRY+A D WN F +HFEY LDINN+E FR L ++ L+ KF IPGNR Sbjct: 62 DLYESIVEFCRYKADDVELWNRFAEHFEYMPLDINNVEAFRGLATLSDQLDAKFNIPGNR 121 Query: 126 MFYLALAPELFGSVSFNLKAGGMLQTRGWNRLVIEKPFGYNLESAEQLNEQIRQVFKEEE 185 +FYLALAP LFG VSF+L+ GG+L+++GW+R+VIEKPFGY+LESA++LN+QI QVFKEEE Sbjct: 122 LFYLALAPSLFGPVSFSLRDGGLLESKGWHRVVIEKPFGYDLESAQKLNDQITQVFKEEE 181 Query: 186 IYRIDHYLGKEMVQNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYYDHAGA 245 IYRIDHYLGKEMVQNI+VIRFANAFFEPLWNN HIAN+Q+TL ETVGVEERGGYYD +GA Sbjct: 182 IYRIDHYLGKEMVQNIQVIRFANAFFEPLWNNNHIANVQVTLSETVGVEERGGYYDKSGA 241 Query: 246 LRDMGQNHMLQLLTMIAMEPPSRLLAEDIRDEKVKVLRSLRPYASSGEVHENVVRGQYTQ 305 LRDMGQNHMLQ+LTMIAMEPPSRL EDIRDEKVKVLRSLRPY SS EV VVRGQY++ Sbjct: 242 LRDMGQNHMLQMLTMIAMEPPSRLHGEDIRDEKVKVLRSLRPYKSSDEVRNQVVRGQYSE 301 Query: 306 GLYKGKTLPAYRQEDKVDPESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKTTEVVV 365 G KGK LP YRQED V S TETYFAA++ VDNFRWAGVPFYIRTGKRLPVKTTEVV+ Sbjct: 302 GSLKGKELPGYRQEDSVGENSTTETYFAAKLAVDNFRWAGVPFYIRTGKRLPVKTTEVVI 361 Query: 366 EFKGMPTNVYLGQKHKLEPNLLVIRVNPMEGIYVKINAKKPGSESEIQPLAMDFCQSCMV 425 EFK MP NV Q+H L+PNLLVIRVNPMEGIY+K+NAK PG ++ +QP+ M+FCQSC + Sbjct: 362 EFKSMPQNVLFAQRHDLQPNLLVIRVNPMEGIYIKMNAKTPGEDNSVQPVNMEFCQSCQI 421 Query: 426 GINSPEAYERLLHDAARGDSTYFTRWDEVSSAWSFVDRIAQAWREGTGDLASYPAGSWGP 485 GIN+PEAYERL+HDA RGDSTYFTRWDEV+ AW FVDRIA AWRE DL YPAGSWGP Sbjct: 422 GINTPEAYERLIHDAVRGDSTYFTRWDEVAQAWEFVDRIAAAWREDPTDLQHYPAGSWGP 481 Query: 486 VEADQLLAREGFHWWPVNGQDEDNVVWQANS 516 +A++LLA++GF WWPVNGQ EDNV+W +NS Sbjct: 482 EKAEKLLAQDGFKWWPVNGQAEDNVIWVSNS 512 >B7GHJ3.1 B7GHJ3_ANOFW Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 495 Score = 624 bits (1610), Expect = e-177, Method: Compositional matrix adjust. Identities = 286/493 (58%), Positives = 375/493 (76%), Gaps = 6/493 (1%) Query: 13 PGAVFFIFGATGDLARRKLFPAIYSLYREGKLTHDFAVIGVARRPRTQEEFREDVKESIQ 72 P A IFGATGDLA+RKLFP+IY LY++GKL FAV+GVARRP T E FR VKE+I+ Sbjct: 6 PKATIIIFGATGDLAKRKLFPSIYKLYQKGKLAEQFAVVGVARRPHTDESFRSYVKETIE 65 Query: 73 EFCRYQAGDASEWNEFVQHFEYKSLDINNIEGFRELNAQTEALEEKFRIPGNRMFYLALA 132 E + + D ++F+ HF Y SLD N + + +LN +EE+F IPGNR+FYLA+A Sbjct: 66 EATKQELID----DKFISHFYYHSLDATNTQSYEQLNELLTRVEEQFHIPGNRIFYLAMA 121 Query: 133 PELFGSVSFNLKAGGMLQTRGWNRLVIEKPFGYNLESAEQLNEQIRQVFKEEEIYRIDHY 192 PE FG+++ +LK+ G+ T GW RLVIEKPFG++L+SA++LNE+IRQ F EE+I+RIDHY Sbjct: 122 PEFFGTITSHLKSEGLTATNGWTRLVIEKPFGHDLQSAQKLNEEIRQSFSEEQIFRIDHY 181 Query: 193 LGKEMVQNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYYDHAGALRDMGQN 252 LGKEMVQNIEVIRFANA FEPLWNN+ IANIQIT ET+GVE+RG YYDH+GALRDM QN Sbjct: 182 LGKEMVQNIEVIRFANAIFEPLWNNRFIANIQITSSETLGVEDRGRYYDHSGALRDMVQN 241 Query: 253 HMLQLLTMIAMEPPSRLLAEDIRDEKVKVLRSLRPYASSGEVHENVVRGQYTQGLYKGKT 312 HMLQ++ ++AMEPP +L +DIR EK+KVLR+LRP + +V VRGQY +G+ +G+ Sbjct: 242 HMLQMVALLAMEPPIKLTTDDIRSEKIKVLRALRP-MTHDDVETYFVRGQYGRGIVRGQE 300 Query: 313 LPAYRQEDKVDPESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKTTEVVVEFKGMPT 372 + YR+E VDP SNTET+ A ++ +DNFRWAGVPFYIRTGKR+ K+T++VV+FK +P Sbjct: 301 VVGYREEHSVDPNSNTETFVAGKLMIDNFRWAGVPFYIRTGKRMTEKSTKIVVQFKDVPM 360 Query: 373 NVYLGQKHKLEPNLLVIRVNPMEGIYVKINAKKPGSESEIQPLAMDFCQSCMVGINSPEA 432 N+Y + PNLLVI + P EGI + +NAKK G + P+ +D+C +C+ GIN+PEA Sbjct: 361 NLYYRTSEHVHPNLLVIHIQPDEGITLHLNAKKSGESMKTTPIKLDYCNNCIDGINTPEA 420 Query: 433 YERLLHDAARGDSTYFTRWDEVSSAWSFVDRIAQAW-REGTGDLASYPAGSWGPVEADQL 491 YE+LL+D RGD+T FT WDEV+++WSFVD I++ W D +Y AGS GP +AD+L Sbjct: 421 YEKLLYDCMRGDATNFTHWDEVAASWSFVDPISEVWANTKAADFPNYEAGSMGPKKADEL 480 Query: 492 LAREGFHWWPVNG 504 L ++GFHWWP+NG Sbjct: 481 LQKDGFHWWPLNG 493 >C5D429.1 C5D429_9BACI Glucose-6-phosphate 1-dehydrogenase EC=1.1.1.49 Length = 496 Score = 595 bits (1534), Expect = e-168, Method: Compositional matrix adjust. Identities = 273/491 (55%), Positives = 370/491 (75%), Gaps = 6/491 (1%) Query: 13 PGAVFFIFGATGDLARRKLFPAIYSLYREGKLTHDFAVIGVARRPRTQEEFREDVKESIQ 72 P ++ IFGATGDLA+RKLFP+IY LY +GKL+ +FAV+GVARRP + +EFR V++S++ Sbjct: 6 PKSLIVIFGATGDLAKRKLFPSIYRLYEKGKLSEEFAVVGVARRPLSNDEFRNYVRQSVE 65 Query: 73 EFCRYQAGDASEWNEFVQHFEYKSLDINNIEGFRELNAQTEALEEKFRIPGNRMFYLALA 132 + D FV HF Y D+ + +++L + + L+E + + GNR+FYLA+A Sbjct: 66 NALNQELSD----QRFVSHFYYHPFDVTDTASYQQLKSLLQQLDEIYHVDGNRIFYLAMA 121 Query: 133 PELFGSVSFNLKAGGMLQTRGWNRLVIEKPFGYNLESAEQLNEQIRQVFKEEEIYRIDHY 192 PE FG+++ LK+ G+ T GW RLVIEKPFG++L+SA+QLNE+IRQ F E EIYRIDHY Sbjct: 122 PEFFGTITSRLKSEGLTATNGWKRLVIEKPFGHDLQSAQQLNEEIRQSFSENEIYRIDHY 181 Query: 193 LGKEMVQNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYYDHAGALRDMGQN 252 LGKEMVQNIEVIRF+NA FEPLWNN+ I+NIQIT ET+GVE+RG YYDH+GALRDM QN Sbjct: 182 LGKEMVQNIEVIRFSNAIFEPLWNNRFISNIQITSSETLGVEDRGRYYDHSGALRDMVQN 241 Query: 253 HMLQLLTMIAMEPPSRLLAEDIRDEKVKVLRSLRPYASSGEVHENVVRGQYTQGLYKGKT 312 HMLQ++ ++AMEPP +L +DIR+EK+KVLR+LRP S EV + VRGQY +G+ GK Sbjct: 242 HMLQMVALLAMEPPIKLTTDDIRNEKIKVLRALRP-ISHEEVDQYFVRGQYGRGIVNGKE 300 Query: 313 LPAYRQEDKVDPESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKTTEVVVEFKGMPT 372 + +YR+E+ VDP SNTET+ A ++ +DNFRWAGVPFYIRTGKR+ K+T++VV+FK +P Sbjct: 301 VVSYREENNVDPNSNTETFVAGKLMIDNFRWAGVPFYIRTGKRMTEKSTKIVVQFKDVPM 360 Query: 373 NVYLGQKHKLEPNLLVIRVNPMEGIYVKINAKKPGSESEIQPLAMDFCQSCMVGINSPEA 432 N+Y K++PNLL+I + P EGI + +N KK G + P+ +D+C +C+ GIN+PEA Sbjct: 361 NLYYRTNEKIQPNLLIIHIQPDEGITLHLNGKKSGEYMKTTPIKLDYCNNCIDGINTPEA 420 Query: 433 YERLLHDAARGDSTYFTRWDEVSSAWSFVDRIAQAWREGTG-DLASYPAGSWGPVEADQL 491 YE+LL+D RGD+T FT WDEV+++W FVD I++ W D +Y AGS GP +D+L Sbjct: 421 YEKLLYDCMRGDATNFTHWDEVAASWQFVDPISEVWENTKAIDFPNYEAGSMGPKASDEL 480 Query: 492 LAREGFHWWPV 502 L ++GFHWWP+ Sbjct: 481 LQKDGFHWWPI 491 >C2WFI6.1 C2WFI6_BACCE Glucose-6-phosphate 1-dehydrogenase Length = 491 Score = 593 bits (1530), Expect = e-167, Method: Compositional matrix adjust. Identities = 270/490 (55%), Positives = 372/490 (75%), Gaps = 5/490 (1%) Query: 19 IFGATGDLARRKLFPAIYSLYREGKLTHDFAVIGVARRPRTQEEFREDVKESIQEFCRYQ 78 IFGATGDLA+RKLFP+IYSLY++G+L+ +FAV+GVARR + + FRE+V SIQE + + Sbjct: 3 IFGATGDLAKRKLFPSIYSLYKKGQLSKNFAVVGVARREWSDDVFRENVLSSIQE-SKIK 61 Query: 79 AGDASEWNEFVQHFEYKSLDINNIEGFRELNAQTEALEEKFRIPGNRMFYLALAPELFGS 138 G+ + +EF+ HF Y + D+ N +++LNA LEE+F IPGNRM+Y+A+APE FG+ Sbjct: 62 PGN--DLDEFLTHFRYLAFDVTNTASYQDLNALITNLEEQFNIPGNRMYYMAMAPEFFGT 119 Query: 139 VSFNLKAGGMLQTRGWNRLVIEKPFGYNLESAEQLNEQIRQVFKEEEIYRIDHYLGKEMV 198 ++ LK+ G+ + GWNRL+IEKPFG++L SA++LNE++R F E+EIYRIDHYLGKEMV Sbjct: 120 IASYLKSEGVTNSSGWNRLIIEKPFGHDLPSAQKLNEELRHAFAEDEIYRIDHYLGKEMV 179 Query: 199 QNIEVIRFANAFFEPLWNNKHIANIQITLGETVGVEERGGYYDHAGALRDMGQNHMLQLL 258 QNI VIRFANA FE LWNN++I+NIQIT E++GVE+RGGYYD++GALRDM QNHMLQ++ Sbjct: 180 QNIGVIRFANAIFESLWNNRYISNIQITSSESLGVEDRGGYYDNSGALRDMVQNHMLQMV 239 Query: 259 TMIAMEPPSRLLAEDIRDEKVKVLRSLRPYASSGEVHENVVRGQYTQGLYKGKTLPAYRQ 318 ++AMEPP RL E+IR EK+K LR+LRP A EV + VR QY G GK +P YR Sbjct: 240 ALLAMEPPIRLTTEEIRSEKIKALRALRPIAVE-EVDQYFVRSQYGPGTINGKEVPGYRS 298 Query: 319 EDKVDPESNTETYFAARVFVDNFRWAGVPFYIRTGKRLPVKTTEVVVEFKGMPTNVYLGQ 378 E+KVDP S TET+ A ++ +DNFRW+GVP YIRTGKR+ K+T++V++FK +P N+Y Sbjct: 299 ENKVDPNSRTETFVAGKLLIDNFRWSGVPIYIRTGKRMQEKSTKIVIQFKELPMNLYSKS 358 Query: 379 KHKLEPNLLVIRVNPMEGIYVKINAKKPGSESEIQPLAMDFCQSCMVGINSPEAYERLLH 438 ++ + PNLL+I + P EGI + +N KK G+ + P +D+C C+ +N+PEAYE+LL+ Sbjct: 359 ENSVHPNLLIIHIQPDEGISLVLNGKKIGTSEKTTPFKLDYCNDCVDRVNTPEAYEKLLY 418 Query: 439 DAARGDSTYFTRWDEVSSAWSFVDRIAQAWREG-TGDLASYPAGSWGPVEADQLLAREGF 497 DA +GD+T FT WDEV+ +W FVD I++AW++ + DL +Y +GS GP +D LLA GF Sbjct: 419 DAIQGDATNFTHWDEVALSWKFVDAISKAWKQDVSTDLLTYESGSMGPQASDDLLAENGF 478 Query: 498 HWWPVNGQDE 507 HWWP++ + Sbjct: 479 HWWPISDDSD 488 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,208,217,115 Number of extensions: 137778211 Number of successful extensions: 312197 Number of sequences better than 1.0e-05: 2176 Number of HSP's gapped: 304101 Number of HSP's successfully gapped: 2180 Length of query: 516 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 376 Effective length of database: 1,741,754,103 Effective search space: 654899542728 Effective search space used: 654899542728 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)