BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0470.0005.p (480 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KFH0.1 B3KFH0_9BACI Response regulator receiver 807 0.0 B1D8F1.1 B1D8F1_9BACL Two component transcriptional regulator, A... 771 0.0 A4XMH2.1 A4XMH2_CALS8 Two component transcriptional regulator, A... 263 3e-68 B1DAL9.1 B1DAL9_9BACL Two component transcriptional regulator, A... 227 2e-57 B1DGK5.1 B1DGK5_9BACL Two component transcriptional regulator, A... 176 4e-42 >B3KFH0.1 B3KFH0_9BACI Response regulator receiver Length = 480 Score = 807 bits (2084), Expect = 0.0, Method: Compositional matrix adjust. Identities = 391/480 (81%), Positives = 424/480 (88%) Query: 1 VYKVMIVDDEAWAIKGICNAFDWDKYGFEIVGQFKSAYNAWDAIRADKPDLVFTDIRMPD 60 +YKVMIVDDE WAIKGI NAFDWDKYGFEI+GQFKSAY AWDAI+A++PDLVFTDIRMP+ Sbjct: 1 MYKVMIVDDEPWAIKGIRNAFDWDKYGFEIIGQFKSAYTAWDAIKANEPDLVFTDIRMPE 60 Query: 61 ISGLDLMKRAKSHGLDTEFVIVSGYAEFEYAQEALRYGALDYFLKPLDIDMADQFIMKLA 120 ISGLDLMKRAK GLD EFVIVSGYAEFEYAQEALRYGALDYFLKPLDID AD FI KLA Sbjct: 61 ISGLDLMKRAKVEGLDIEFVIVSGYAEFEYAQEALRYGALDYFLKPLDIDKADPFIAKLA 120 Query: 121 MHFSRRSEARNQILLDALTSADEDEIKRLLPYSGCAAVCYYQVLAIYFEGENKDFKKLLS 180 MHFSRRS ARNQ+LLDALTS +ED IK LP AAV YYQVL IYFEGE+K+ + LLS Sbjct: 121 MHFSRRSTARNQLLLDALTSVNEDAIKSFLPLPDDAAVYYYQVLTIYFEGEHKNIRNLLS 180 Query: 181 LEGKPVYAVEVEAGTRKMLVVLITEHRAYLEGNWDERILNKTXXXXXXXXXXXXELKHMS 240 LEGKPV+ VEVEAG RKMLVVL+TEHR LEG+ D+R+LNKT +LKHMS Sbjct: 181 LEGKPVHVVEVEAGARKMLVVLMTEHRDCLEGHSDKRVLNKTGIHVMGVSSISNQLKHMS 240 Query: 241 KLIKEADLSASRVFLEEAAGAVHYEPKLHLVKPCIDRLYSIVQGNQFDNMDVYIKGLQKY 300 KLIKEADLSAS+VFLEEA G VHYEPKLHLVK CID ++ I+QGNQFD+++ YIKGLQ Y Sbjct: 241 KLIKEADLSASQVFLEEAGGVVHYEPKLHLVKSCIDEIHHILQGNQFDDVEAYIKGLQAY 300 Query: 301 FRDHHLGMCEVVYLWNQAVGILVNAYPEELKDMELEFLNYSEIKERFEHFESLCSFLYEV 360 FRDHHLGM EVVYLWNQAVGIL+ AY EELKDMELEFLNYSEIKERFEHFESLCSFL+EV Sbjct: 301 FRDHHLGMSEVVYLWNQAVGILIKAYSEELKDMELEFLNYSEIKERFEHFESLCSFLHEV 360 Query: 361 LASIRQENSRSLQEGDILSCFNKMIAYINQHFEQKLYLKDLSAQFFINQVYCCQFFKKNL 420 L SIR NSRSLQEGDI SCFN+MI YIN HFEQKLYLKDLSAQFFINQVYCCQ F+KNL Sbjct: 361 LDSIRIGNSRSLQEGDIQSCFNRMINYINHHFEQKLYLKDLSAQFFINQVYCCQLFRKNL 420 Query: 421 GKTFSEYVSDLRIKKARELLKQTDLSIEKIAIKSGYVDYYYFNKVFKKHCGMTPTKFRKS 480 GKTFSEYVS+LRIKKARELLK+TDLSIE++AIK+GYVDYYYFNKVFKKHCGMTPTKFRKS Sbjct: 421 GKTFSEYVSELRIKKARELLKRTDLSIEEVAIKAGYVDYYYFNKVFKKHCGMTPTKFRKS 480 >B1D8F1.1 B1D8F1_9BACL Two component transcriptional regulator, AraC family Length = 481 Score = 771 bits (1992), Expect = 0.0, Method: Compositional matrix adjust. Identities = 367/480 (76%), Positives = 417/480 (86%) Query: 1 VYKVMIVDDEAWAIKGICNAFDWDKYGFEIVGQFKSAYNAWDAIRADKPDLVFTDIRMPD 60 +YKVMIVDDE+WAIKGI NAFDWDKYGFEI+GQF SAY AWDAI A+KPDLVFTDIRMPD Sbjct: 1 MYKVMIVDDESWAIKGIRNAFDWDKYGFEIIGQFTSAYKAWDAILAEKPDLVFTDIRMPD 60 Query: 61 ISGLDLMKRAKSHGLDTEFVIVSGYAEFEYAQEALRYGALDYFLKPLDIDMADQFIMKLA 120 ISGLDLMKRAKSH LD EFVIVSGYAEF+YAQEALRYGAL+YFLKPLD+DMAD FI +LA Sbjct: 61 ISGLDLMKRAKSHDLDIEFVIVSGYAEFKYAQEALRYGALNYFLKPLDVDMADSFIAELA 120 Query: 121 MHFSRRSEARNQILLDALTSADEDEIKRLLPYSGCAAVCYYQVLAIYFEGENKDFKKLLS 180 MHFS+R ARNQ+LLDALTS +EDEIKR LP C AVCYYQVL+I F+G+NKDF KL + Sbjct: 121 MHFSKRGAARNQLLLDALTSPNEDEIKRYLPLPDCGAVCYYQVLSIDFKGDNKDFGKLFT 180 Query: 181 LEGKPVYAVEVEAGTRKMLVVLITEHRAYLEGNWDERILNKTXXXXXXXXXXXXELKHMS 240 LEGKPV AVEVEAG K L+VL+ E++ LE DE + T +L +M Sbjct: 181 LEGKPVTAVEVEAGANKRLIVLMAENKDCLEELRDELAVKNTGMNTVGISSISSQLTNMG 240 Query: 241 KLIKEADLSASRVFLEEAAGAVHYEPKLHLVKPCIDRLYSIVQGNQFDNMDVYIKGLQKY 300 KLIKEADLSAS+ FL++ A VHYEPK++LVKPCID +Y I+QGN+FD+M+ YI GLQ Y Sbjct: 241 KLIKEADLSASQAFLDDGASVVHYEPKVYLVKPCIDEIYRIIQGNRFDDMEAYINGLQAY 300 Query: 301 FRDHHLGMCEVVYLWNQAVGILVNAYPEELKDMELEFLNYSEIKERFEHFESLCSFLYEV 360 F+D HLGM EVVYLWNQAVGIL+NAY EELKDME+EFLNYSEIKERFEHFESLCSFL++V Sbjct: 301 FKDQHLGMSEVVYLWNQAVGILINAYAEELKDMEMEFLNYSEIKERFEHFESLCSFLHDV 360 Query: 361 LASIRQENSRSLQEGDILSCFNKMIAYINQHFEQKLYLKDLSAQFFINQVYCCQFFKKNL 420 LASI Q NSRSLQEGDILSCFN+M+AYI+ H+EQKLYLKDLSAQF+INQVYCCQ FKKNL Sbjct: 361 LASITQGNSRSLQEGDILSCFNRMVAYIDSHYEQKLYLKDLSAQFYINQVYCCQLFKKNL 420 Query: 421 GKTFSEYVSDLRIKKARELLKQTDLSIEKIAIKSGYVDYYYFNKVFKKHCGMTPTKFRKS 480 GKTFSEYVS+LRIKKARELLK+TDLSIE+IAI++GYV+YYYFNKVFKKHCG+TP+KFRKS Sbjct: 421 GKTFSEYVSELRIKKARELLKKTDLSIEEIAIQTGYVEYYYFNKVFKKHCGITPSKFRKS 480 >A4XMH2.1 A4XMH2_CALS8 Two component transcriptional regulator, AraC family Length = 476 Score = 263 bits (672), Expect = 3e-68, Method: Compositional matrix adjust. Identities = 164/490 (33%), Positives = 256/490 (52%), Gaps = 34/490 (6%) Query: 1 VYKVMIVDDEAWAIKGICNAFDWDKYGFEIVGQFKSAYNAWDAIRADKPDLVFTDIRMPD 60 ++KV++VDDE G+ F+W +GFEI+G+ + Y A D I+ PD+VF DIRMP+ Sbjct: 1 MFKVLLVDDEPLTFIGLKKIFNWQTWGFEIIGETTNPYEAIDLIKTLHPDVVFIDIRMPE 60 Query: 61 ISGLDLMKRAKSHGLDTEFVIVSGYAEFEYAQEALRYGALDYFLKPLDIDMADQFIMKLA 120 +SG+D+M++ + +DTEFV+VSGYAEF +AQ+A++YGA DY LKP++ID D + +L Sbjct: 61 LSGIDIMRKIREENVDTEFVVVSGYAEFSFAQQAIKYGAFDYCLKPINIDQEDNLLQRLF 120 Query: 121 MHFSRRSEARNQILLD-----ALTSADEDEIKRLLPYSGCAAVCYYQVLAIYFEGENKDF 175 H + RN L + LT D + + PY G YF G Sbjct: 121 EHLISKKLKRNLELFENCVDKKLTLKDFLSLINI-PYEGQ-----------YFRG----- 163 Query: 176 KKLLSLEGKPVYAVEVEAGTRKMLVVLITEHRAYLEGNWDERILNKTXXXXXXXXXXXXE 235 +S E Y + + V +T + + + +E ++ Sbjct: 164 VFWISPEKSTEYIYQFLRQKEVLFFVKLTPQKYFFIISCEEIPID--YLPYLRDGIIGIS 221 Query: 236 LKH-----MSKLIKEADLSASRVFLEEAAGAVHY-EPKLHLVKPCIDRLYSIVQGNQFDN 289 + H S + +A +A F+ + G Y P +V I+ + S ++ +N Sbjct: 222 IPHTQDSLFSNVFSQAHEAAYNSFIYQNNGVFEYSNPCYIIVNQLINDISSTIEKKDSEN 281 Query: 290 MDVYIKGLQKYFRDHHLGMCEVVYLWNQAVGILVNAYPEELKDMELEFLNYSEIKERFEH 349 + LQ +F+ + L + +V Y WNQ L P E DM + + Y EI F + Sbjct: 282 LKNIFFNLQGFFKSNKLTIGDVTYFWNQLSLYLNKLNPSEYSDMSI--MEYDEIANTFCN 339 Query: 350 FESLCSFLYEVLASIRQENSRSLQEGDILSCFNKMIAYINQHFEQKLYLKDLSAQFFINQ 409 E++ +L E + + +N + + F K+I YI+ H+ + L LK+LSA+FFI+ Sbjct: 340 IENMSEYLLERIEGVITKNKQFEYCSN--ENFLKLIEYIDNHYSEPLSLKELSAKFFISL 397 Query: 410 VYCCQFFKKNLGKTFSEYVSDLRIKKARELLKQTDLSIEKIAIKSGYVDYYYFNKVFKKH 469 YCC+ F+K +G +F+EY+++LR+KKA ELLK T+ S+ +IA GY DYY+FNK FKK Sbjct: 398 NYCCELFRKVIGCSFTEYLTNLRMKKAEELLKTTNYSVAEIARLVGYNDYYHFNKAFKKF 457 Query: 470 CGMTPTKFRK 479 G P FRK Sbjct: 458 YGTPPATFRK 467 >B1DAL9.1 B1DAL9_9BACL Two component transcriptional regulator, AraC family Length = 472 Score = 227 bits (578), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 148/484 (30%), Positives = 238/484 (49%), Gaps = 22/484 (4%) Query: 1 VYKVMIVDDEAWAIKGICNAFDWDKYGFEIVGQFKSAYNAWDAIRADKPDLVFTDIRMPD 60 ++KV+IVDDE+W ++ + + DW +YGFE+ GQ + +A +A+R +PD+VFTDIRMP+ Sbjct: 1 MHKVLIVDDESWVLESLKDLVDWARYGFEVAGQANNGTDALEAMRRLRPDVVFTDIRMPE 60 Query: 61 ISGLDLMKRAKSHGLDTEFVIVSGYAEFEYAQEALRYGALDYFLKPLDIDMADQFIMKLA 120 +SGL+L++R +S G FV+VSGYAEF YAQ+A+ YGA+ Y LKP D +MKL Sbjct: 61 MSGLELIQRGRSVGFPVHFVVVSGYAEFAYAQKAMSYGAVAYCLKPFDEPEISGVLMKLG 120 Query: 121 MHFSRRSEARNQILLDALTSADEDEIKRL---LPYSGCAAVCYYQVLAIYFEGENKDFKK 177 + L+ L ED +L L G ++ + G+ + Sbjct: 121 KLLDAAKGTADSPLVQLLEEPSEDARAKLQGELERIGIGDWATAGIVPVVSVGQG----E 176 Query: 178 LLSLEGKPVYAVEVEAGTRKMLVVLITEHRAYLEGNWDERILNKTXXXXXXXXXXXXELK 237 L L G ++ ++ G K +L L W + +L Sbjct: 177 LPGLRGP---SIRLKMGPSKTAYLLGAVKAEELASGWRRQF--PPDLSGIGIGAGITDLS 231 Query: 238 HMSKLIKEADLSASRVFLEEAAGAVHYEP-KLHLVKPCIDRLYSIVQGNQFDNMDVYIKG 296 + I AD+ A + F+ G + P K + + + + + +D + Sbjct: 232 GVRSAIAGADMLAHQFFVTGKRGVYEHRPYKENELNRRMSEISDAIAAVDMPAIDAAFRH 291 Query: 297 LQKYFRDHHLGMCEVVYLWNQAVGILVNAYPEELKDMELEFLNYSEIKERF-EHFESLCS 355 + + FR+ L ++N + L +L E +Y ++ + F + F+ L Sbjct: 292 IAELFREDALSTRHAFRVYNMTISFLF-----KLGQTEETLYSYEQLVQSFGDVFDMLGE 346 Query: 356 FLYEVLASIRQENSRSLQEGDILSCFNKMIAYINQHFEQKLYLKDLSAQFFINQVYCCQF 415 V+ R + + + FN+++ Y+ HF ++L L+ LS QFF+N Y Q Sbjct: 347 LQALVVRHCRGGEAHPPETKN--RTFNQILQYVTDHFREELSLQGLSEQFFMNPSYISQL 404 Query: 416 FKKNLGKTFSEYVSDLRIKKARELLKQT-DLSIEKIAIKSGYVDYYYFNKVFKKHCGMTP 474 FKK +G+TF Y+S LRI A +LL + D SI +IA K GY DY+YF ++FKK G TP Sbjct: 405 FKKEVGETFVGYISQLRIAHACKLLDENDDYSIHEIAEKIGYNDYFYFARLFKKMTGKTP 464 Query: 475 TKFR 478 T++R Sbjct: 465 TQYR 468 >B1DGK5.1 B1DGK5_9BACL Two component transcriptional regulator, AraC family Length = 483 Score = 176 bits (447), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 131/503 (26%), Positives = 236/503 (46%), Gaps = 45/503 (8%) Query: 1 VYKVMIVDDEAWAIKGICNAFDWDKYGFEIVGQFKSAYNAWDAIRADKPDLVFTDIRMPD 60 +Y+V+IVDDE W GI DW+ G++++GQ +A I +P++V +DIRMP Sbjct: 1 MYRVLIVDDEPWVAYGISKLIDWETEGYQVIGQAYDGSSALRFIEEHRPEVVVSDIRMPG 60 Query: 61 ISGLDLMKRAKSHGLDTEFVIVSGYAEFEYAQEALRYGALDYFLKPLDIDMADQFIMKLA 120 ++G++L+ L TE ++ SGY+EFEYAQ+ALR GA DY LK ++ + + IM+L Sbjct: 61 LNGIELLNEIAKQKLGTEVILASGYSEFEYAQQALRLGAFDYLLKQIEKEQLLETIMRLR 120 Query: 121 MHFSRRSEARNQILLDAL-TSADEDEIKRLLPYSGCAAVCYY-----------QVLAI-- 166 H ++ LDA A +++ LL G + Y VL I Sbjct: 121 GHLEQKK-------LDAGDPDAPLNDLFELLDADGNTTIGQYLCNRGMKPEHSNVLLINA 173 Query: 167 --YFEGENKDFKKLLSLEGKPVYAVEVEAGTRKMLVVLITEHRAYLEGNWDERILNKTXX 224 ++ +++ L G + + G+ K+ +L+ + A+ + + I Sbjct: 174 VFWYATVTDSSERVAKLSGMDAHVMRT--GSNKLSYILLYDEAAH-SADLLDFITGNLKD 230 Query: 225 XXXXXXXXXXELKH-MSKLIKEADLSASRVFLEEAAGAVHY---EPKLHLVKPCIDRLYS 280 +L + +SK+ AD++ V Y E + + +L Sbjct: 231 ASHIGISMPSDLSYPLSKVFHAADIALFTSCFYPDHRIVRYKEHEATAAGISGTMLQLEL 290 Query: 281 IVQGNQFDNMDVYIKGLQKYFRDHHLGMCEVVYLWNQAVGILVNAYPEELKDMELEFLNY 340 ++ + M ++ L + R L VY NQ + ++ Y + ++EFL Sbjct: 291 SMKERKLTGMQECLQRLMEQCRGMQLDQFASVY--NQIISLIHKYYSQASSQQDIEFLTC 348 Query: 341 SEIKERFEHFESLCSFLYEVLASIRQENSRSLQEGDILSCFNKMIA----YINQHFEQKL 396 ++ + +++ R +N L+ L + + YI+ F + + Sbjct: 349 DQLARIYSSIDAVFE---------RLKNGFELEGTPDLPVISGQVKAVMDYIDTSFTEDI 399 Query: 397 YLKDLSAQFFINQVYCCQFFKKNLGKTFSEYVSDLRIKKARELLKQTDLSIEKIAIKSGY 456 L ++ +F ++ Y KK G ++S+Y++ RI A+ELLK++ +S+ ++ + GY Sbjct: 400 MLGAIAKRFNLSLSYLSFLIKKEAGTSYSDYITGKRIALAKELLKESSISVHEVVERVGY 459 Query: 457 VDYYYFNKVFKKHCGMTPTKFRK 479 DY++FNK+FKKH G+TP+KFRK Sbjct: 460 KDYFHFNKLFKKHVGLTPSKFRK 482 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.412 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,667,916,454 Number of extensions: 107056595 Number of successful extensions: 326269 Number of sequences better than 1.0e-05: 6631 Number of HSP's gapped: 331878 Number of HSP's successfully gapped: 7288 Length of query: 480 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 340 Effective length of database: 1,741,754,103 Effective search space: 592196395020 Effective search space used: 592196395020 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 133 (55.8 bits)