BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0459.0010.p (243 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value Q183B2.1 Q183B2_CLOD6 Butyrate--acetoacetate CoA-transferase sub... 202 2e-50 C3WZP9.1 C3WZP9_9FUSO Acetoacetate:butyrate/acetate coenzyme A t... 199 1e-49 Q8RHY3.1 Q8RHY3_FUSNN Acetoacetate:butyrate/acetate coenzyme A t... 197 5e-49 A8MJB1.1 A8MJB1_ALKOO 3-oxoacid CoA-transferase, A subunit EC=2.... 197 8e-49 Q7P2G9.1 Q7P2G9_FUSNV ACETOACETATE:BUTYRATE/ACETATE COENZYME A T... 196 2e-48 >Q183B2.1 Q183B2_CLOD6 Butyrate--acetoacetate CoA-transferase subunit A EC=2.8.3.9 Length = 218 Score = 202 bits (515), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 104/218 (47%), Positives = 147/218 (67%), Gaps = 1/218 (0%) Query: 24 NKLISAEDAVKKVKDGDTVMVGGFLAGGHPEQLVRALVETHSAGNLTIISNDTGTTELSI 83 NK++S ++A+ VKDGDT+MVGGF+A G PE L+ L + + +LT+I NDTG + + Sbjct: 2 NKIVSIDEALSHVKDGDTIMVGGFMANGSPENLIDYLC-SKNIKDLTLICNDTGFIDKGV 60 Query: 84 YKLVKSGRVKRIYASYIGSNPETGRLLMTKEAEVSLFPQGTLAEKIRXXXXXXXXXXXXX 143 K+V + + K+I AS++G N ETGR + E +V L PQGTLAE+IR Sbjct: 61 GKMVVNKQFKKIIASHVGLNKETGRQMNNNETDVELVPQGTLAEQIRAAGYGLGGILTPT 120 Query: 144 XXXXIVEEGKRKVDIDGREYLLELPLKADVALIRAHKADEAGNLVINGSSRNFNFVMAMA 203 +VEEGK+K+ +D +EYLLE P+ ADVAL+ A K D+AGNLV GS NFN +MA A Sbjct: 121 GIGTLVEEGKQKIVVDSKEYLLEKPIYADVALLFASKVDKAGNLVYKGSMNNFNNLMASA 180 Query: 204 ADYVVAQTDEYVKLGEIDPNHVNVPGIFIDAIVKVGDM 241 A + ++DE V++G+IDPN VN PGIF++ IV+ G++ Sbjct: 181 AKITIVESDEIVEIGDIDPNEVNTPGIFVNYIVEGGNL 218 >C3WZP9.1 C3WZP9_9FUSO Acetoacetate:butyrate/acetate coenzyme A transferase Length = 217 Score = 199 bits (507), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 101/216 (46%), Positives = 145/216 (67%), Gaps = 1/216 (0%) Query: 22 MNNKLISAEDAVKKVKDGDTVMVGGFLAGGHPEQLVRALVETHSAGNLTIISNDTGTTEL 81 M KL+S E+A+ +KDG TV +GGFLA G PE ++ ALVE +LTI++NDTG + Sbjct: 1 MRQKLVSMEEAISHIKDGMTVHIGGFLACGTPESIITALVE-KGVKDLTIVANDTGYVDR 59 Query: 82 SIYKLVKSGRVKRIYASYIGSNPETGRLLMTKEAEVSLFPQGTLAEKIRXXXXXXXXXXX 141 I +LV + +VK++ AS+IG+NPETGR + + E EV L PQGTLAE++R Sbjct: 60 GIGRLVVNNQVKKVIASHIGTNPETGRRMQSGEMEVELVPQGTLAERVRAGGYGLGGILT 119 Query: 142 XXXXXXIVEEGKRKVDIDGREYLLELPLKADVALIRAHKADEAGNLVINGSSRNFNFVMA 201 IV+EGK+ +++DG++YLLE P+KADVAL+ K DE GN++ +++NFN +MA Sbjct: 120 PTGLGTIVQEGKQIINVDGKDYLLEKPIKADVALLFGSKVDELGNVICEKTTKNFNPLMA 179 Query: 202 MAADYVVAQTDEYVKLGEIDPNHVNVPGIFIDAIVK 237 AAD V+ + E V +G + P H+++ IFID IVK Sbjct: 180 TAADLVIVEALEVVPVGSLSPEHLDISRIFIDYIVK 215 >Q8RHY3.1 Q8RHY3_FUSNN Acetoacetate:butyrate/acetate coenzyme A transferase EC=2.8.3.9 Length = 217 Score = 197 bits (502), Expect = 5e-49, Method: Compositional matrix adjust. Identities = 100/216 (46%), Positives = 144/216 (66%), Gaps = 1/216 (0%) Query: 22 MNNKLISAEDAVKKVKDGDTVMVGGFLAGGHPEQLVRALVETHSAGNLTIISNDTGTTEL 81 M K++S E+A+ VKDG TV +GGF+A G PE ++ AL+E +LTI++NDTG + Sbjct: 1 MKQKIVSMEEAISHVKDGMTVHIGGFIACGTPESIITALIE-KGVKDLTIVANDTGLIDK 59 Query: 82 SIYKLVKSGRVKRIYASYIGSNPETGRLLMTKEAEVSLFPQGTLAEKIRXXXXXXXXXXX 141 I +LV + +VK++ AS+IG+NPETGR + + E EV L PQGTLAE++R Sbjct: 60 GIGRLVVNNQVKKVIASHIGTNPETGRRMQSGEMEVELVPQGTLAERVRAAGYGLGGILT 119 Query: 142 XXXXXXIVEEGKRKVDIDGREYLLELPLKADVALIRAHKADEAGNLVINGSSRNFNFVMA 201 IV+EGK+ +++DG++YLLE P+KADVALI K DE GN++ +++NFN +MA Sbjct: 120 PTGLGTIVQEGKQIINVDGKDYLLEKPIKADVALIFGTKVDELGNVICEKTTKNFNPLMA 179 Query: 202 MAADYVVAQTDEYVKLGEIDPNHVNVPGIFIDAIVK 237 AAD V+ + E V G + P H+++ IFID IVK Sbjct: 180 TAADVVIVEALEIVPAGSLSPEHLDISRIFIDYIVK 215 >A8MJB1.1 A8MJB1_ALKOO 3-oxoacid CoA-transferase, A subunit EC=2.8.3.8 Length = 217 Score = 197 bits (500), Expect = 8e-49, Method: Compositional matrix adjust. Identities = 100/212 (47%), Positives = 141/212 (66%), Gaps = 1/212 (0%) Query: 25 KLISAEDAVKKVKDGDTVMVGGFLAGGHPEQLVRALVETHSAGNLTIISNDTGTTELSIY 84 K+++ E+A+ V+DG TVMVGGFL G P +++ ALVE +LT+I NDT + + Sbjct: 3 KIVNMEEAISHVQDGMTVMVGGFLGSGSPHKIIDALVE-KGVKDLTLICNDTAFVDAGVG 61 Query: 85 KLVKSGRVKRIYASYIGSNPETGRLLMTKEAEVSLFPQGTLAEKIRXXXXXXXXXXXXXX 144 K++ + + K++ S+IG+N ETGR + KE EV L PQGTLAE++R Sbjct: 62 KMIVTKQFKKVIVSHIGTNKETGRQMNEKETEVVLVPQGTLAEQVRAGGAGLGGILTPTG 121 Query: 145 XXXIVEEGKRKVDIDGREYLLELPLKADVALIRAHKADEAGNLVINGSSRNFNFVMAMAA 204 +VEEGK+K+++ G+ YLLELPL+ADVALI +K D+ GN+ G+SRNFN +MAMAA Sbjct: 122 VGTLVEEGKQKIEVGGKTYLLELPLRADVALIFGNKVDKKGNIYFEGASRNFNTLMAMAA 181 Query: 205 DYVVAQTDEYVKLGEIDPNHVNVPGIFIDAIV 236 D V+ + +E V++G I P V PGIFID IV Sbjct: 182 DTVIIEAEEIVEVGSIAPQDVVTPGIFIDYIV 213 >Q7P2G9.1 Q7P2G9_FUSNV ACETOACETATE:BUTYRATE/ACETATE COENZYME A TRANSFERASE EC=2.8.3.9 Length = 217 Score = 196 bits (498), Expect = 2e-48, Method: Compositional matrix adjust. Identities = 98/216 (45%), Positives = 144/216 (66%), Gaps = 1/216 (0%) Query: 22 MNNKLISAEDAVKKVKDGDTVMVGGFLAGGHPEQLVRALVETHSAGNLTIISNDTGTTEL 81 M K++S E+A+ +KDG TV +GGF+A G PE ++ AL+E +LTI++NDTG + Sbjct: 1 MKQKIVSMEEAISHIKDGMTVHIGGFIACGTPESIITALIE-KGVKDLTIVANDTGLIDK 59 Query: 82 SIYKLVKSGRVKRIYASYIGSNPETGRLLMTKEAEVSLFPQGTLAEKIRXXXXXXXXXXX 141 I +LV + +VK++ AS+IG+NPETGR + + E EV L PQGTLAE++R Sbjct: 60 GIGRLVVNNQVKKVIASHIGTNPETGRRMQSGEMEVELVPQGTLAERVRAGGYGLGGILT 119 Query: 142 XXXXXXIVEEGKRKVDIDGREYLLELPLKADVALIRAHKADEAGNLVINGSSRNFNFVMA 201 IV+EGK+ +++DG++YLLE P++ADVALI K DE GN++ +++NFN +MA Sbjct: 120 PTGLGTIVQEGKQIINVDGKDYLLEKPIRADVALIFGTKVDELGNVICEKTTKNFNPLMA 179 Query: 202 MAADYVVAQTDEYVKLGEIDPNHVNVPGIFIDAIVK 237 AAD V+ + E V G + P H+++ IFID IVK Sbjct: 180 TAADVVIVEALEIVPAGSLSPEHLDISRIFIDYIVK 215 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.316 0.135 0.369 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,186,049,309 Number of extensions: 42393670 Number of successful extensions: 126004 Number of sequences better than 1.0e-05: 1147 Number of HSP's gapped: 123970 Number of HSP's successfully gapped: 1164 Length of query: 243 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 111 Effective length of database: 1,817,122,223 Effective search space: 201700566753 Effective search space used: 201700566753 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 129 (54.3 bits)