BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0459.0004.p (1044 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B9MQD5.1 B9MQD5_ANATD Diguanylate cyclase/phosphodiesterase with... 510 e-142 A4XFJ6.1 A4XFJ6_CALS8 Diguanylate cyclase/phosphodiesterase with... 499 e-139 B8I783.1 B8I783_CLOCE Diguanylate cyclase/phosphodiesterase 449 e-124 Q3AAV9.1 Q3AAV9_CARHZ Sensory box/GGDEF domain/EAL domain protein 432 e-119 Q8RAV9.1 Q8RAV9_THETN Diguanylate cyclase/phosphodiesterase doma... 432 e-118 >B9MQD5.1 B9MQD5_ANATD Diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(S) Length = 1016 Score = 510 bits (1314), Expect = e-142, Method: Compositional matrix adjust. Identities = 327/1064 (30%), Positives = 543/1064 (51%), Gaps = 98/1064 (9%) Query: 6 LLLLISIVFMLAPPASAHAERQEIRYQAELGYPPYKYLQNGYLTGFDIDLTSMIFEKQSY 65 +L + +++ ML + A+A ++++ + YPP+ Y G + GF IDL +++FE + Sbjct: 7 ILFVFTVLLMLFHISLANASHTPVKFEVDKNYPPFSYTSGGRIYGFTIDLANLVFEPDKF 66 Query: 66 LIHYSTGEWEGTYKRLTRGEIDTTGLMAVTEERKKDTLFSKPVFKSYISVYSRQALQEEI 125 + S+ EW YK+L G+ID T +A+ EERKK+ FSKP+F ++ +Y+ + + I Sbjct: 67 KLELSSDEWSQVYKKLVEGKIDVTAPVAIIEERKKEVHFSKPIFTRHVGLYTSKEFSKNI 126 Query: 126 KLSTLKNYKVGVGKKQYSETVLRNQTDVSQYIQYATVPQALEALKKGEIDLLFENQEVVD 185 L L+++ VGV + Y+ET+L+ + V++Y Y T+ + AL G+ID +QE+ + Sbjct: 127 SLKNLEDFMVGVMQSDYTETLLKEKLGVNKYYTYPTIEDLIYALVDGKIDAALMSQEIAN 186 Query: 186 YLIVEQGLTGNIVRRLSNLYPQDVAYGISKSEPQLVTYINARLDRLQQSGAFEELYQQYF 245 Y +V+ L+ ++ N++ A+ +SK P+LV YIN RL+ L G F+ELY YF Sbjct: 187 YFLVKNNLSDRAELKIKNIFTVKSAFAVSKKRPELVAYINQRLNFLINKGIFDELYYNYF 246 Query: 246 FTHSENYTSMXXXXXXXXXXXXLFLLVTVIAALRIYI-------RHLRRTIHSEQAFFRD 298 T+S Y L+LL+ ++ A + I R L R + + + + Sbjct: 247 STYSPEYFE---RKNRQILLSALYLLIIILFAASVIIFVMTRINRGLERGKQAYEKYAQL 303 Query: 299 VIEHSGMIVWAVHADKRIIRFNQYAASMTGLKEKDVLGANLDEIPGLSGGXXXXXXXXXX 358 + E++ IV ++ II FN++A +TG K ++V+G +I Sbjct: 304 LAENANAIVLTLNLKGEIIYFNKFAEQITGYKSEEVVGKKWVDI-------------FIP 350 Query: 359 XXYQDYVSNV-----ELK-LPDHSPE-------ARYFSFRTALIQGMDTQAEDIFVLVGM 405 ++Y+ N+ E+K L DH E R+ + LI+ E + + G+ Sbjct: 351 SHRREYIENLFKRISEVKILNDHENEIVTKNGDTRWILWNNTLIEN-PYLNEPLIISTGL 409 Query: 406 DVEECKQNELKLQHSXXXXXXXXXXXXXXXXXXXXXFNKLEASERRFRLASEGSGAYMWE 465 D+ + K+ + L+ S L + +++ E +WE Sbjct: 410 DITQIKRTQQLLEESYEEIEQTNQELMNTLDILNKQSEMLMEEKEKYKFLVENVSDCIWE 469 Query: 466 LDWESGMYNLSERWYEVMGYTKEE-----INSFED--GVLSIIHPDDQEPARQARQEHLA 518 +D+ +E+ E G K++ I S D L H DD+ + Q+ + Sbjct: 470 IDF-------NEKKIEFYGKLKDQFDIDVIKSKNDFSAWLEFFHEDDRATVFKKLQDAIL 522 Query: 519 GLTPIYEIEYRMRTKDNRYVWFEVRGKAIVDPKDKIVLFLGSLIDISKRKQAEFQLGNSY 578 E E R+R K + W + + + +DK + ID + +K+ E ++ Sbjct: 523 LHEEKVEFESRIRDKHGNWRWISSHVQILYNEEDKPEKIIAVNIDWTAKKEYEHRI---- 578 Query: 579 QELEATYEQLTATQEELVGQYDMLLENQKNMHRLAYMDSLSSLPNRILLLDTMESYFHRP 638 +AY D+L++LPNR L D +ES + Sbjct: 579 -------------------------------EYIAYYDALTNLPNRKLFEDRLESLIKKA 607 Query: 639 ---GGKAALLFVDTDNFKYINDTLGHKSGD----ILIRQASERLQSVMREGDMLSRLGGD 691 + A++ +D DNFK IND GH++GD + ++ E L S+ + +R+GGD Sbjct: 608 EDEKTQGAVVLIDIDNFKDINDLYGHEAGDEYLIAVTKKILEYLNSI-KLNTFFARVGGD 666 Query: 692 EFVVFIKDVEDRAEVLNLAESILRSFRRSFLIG--ESNLYISVSIGISFYPEDGETTEEI 749 EF V + + + EV+ + +L F I E ++ S SIG+SFYP+DG + +EI Sbjct: 667 EFAVILDGLAKKEEVIEVCTKLLGIFESEIYIQKIEGCIFTSASIGVSFYPDDGRSVKEI 726 Query: 750 LMNADVAMYRAKEEGKNTFVVYDKSMHMSFNERMNIEKHLRSAMNNNEFELHYQPQVEIK 809 N D+A+ AKE GKN F ++ M M +++ IEK L+ A+ ++FEL+YQP + +K Sbjct: 727 FRNVDMALSSAKENGKNDFQIFMPFMLMKNFKKIEIEKSLKKAIEADQFELYYQPVINLK 786 Query: 810 TGLITGFEALIRWNSPVLGFVSPLSFIKIAEDSRLIIYIGEWVLREASAFMKSMNDRTGL 869 I EAL+RW SP G +SPL FI +AEDS LI+ IGE V+ +A + +K+ ++ G+ Sbjct: 787 DMEIHSVEALLRWVSPEKGIISPLEFIPVAEDSGLIVKIGEMVIEKAFSDLKNW-EKKGI 845 Query: 870 PY-KISVNISIIQLLQDDFVDIVLDSLEESGLAPNCLELEITESIFMESFENTVSKLEFL 928 Y +++NIS QL F ++ +E G+ P + EITE+ +E+F+ ++ L FL Sbjct: 846 SYLHMAINISARQLKTKFFEKMIQKQIERYGVNPQKISFEITETGAVENFDVSLKILSFL 905 Query: 929 KSRGIRIALDDFGTGYSSLSYLQQLPISTLKMDKIFIDSLADQGYSQSFVQTIIILGHKM 988 GI+ +DDFGTGYSSL YL++LPI +K+D+ FI + S++ V+ II++ HK+ Sbjct: 906 CQLGIKFLIDDFGTGYSSLIYLRRLPIGGVKIDRSFISEIELSKESRAIVEGIILMAHKL 965 Query: 989 GLDVVAEGVEDADQLAFLKEADCDKVQGYLISRPVPQRGVIELL 1032 L V+AEGVE +L LKE CD QGYL S+PVP+ + +LL Sbjct: 966 DLKVIAEGVETKRELEILKEIGCDFAQGYLFSKPVPKTEIEKLL 1009 >A4XFJ6.1 A4XFJ6_CALS8 Diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(S) Length = 1015 Score = 499 bits (1284), Expect = e-139, Method: Compositional matrix adjust. Identities = 323/1051 (30%), Positives = 530/1051 (50%), Gaps = 62/1051 (5%) Query: 1 MKRCQLLLLISIVFMLAPPASAHAERQEIRYQAELGYPPYKYLQNGYLTGFDIDLTSMIF 60 MKR +++ISI+ A+ + I++Q + YPP+ Y+ NG + GF DL ++IF Sbjct: 1 MKRTLKVIIISILLFFLTSQVAYCYHKTIKFQVDKQYPPFSYVINGRVYGFSGDLANLIF 60 Query: 61 EKQSYLIHYSTGEWEGTYKRLTRGEIDTTGLMAVTEERKKDTLFSKPVFKSYISVYSRQA 120 E Y + S+ WE YKRL GEID TG + + EERKKD F+ P+F ++ +Y+R+ Sbjct: 61 EPDKYFLSVSSDTWENVYKRLVSGEIDITGPIVILEERKKDVYFTDPIFTRHVGIYTRKD 120 Query: 121 LQEEIKLSTLKNYKVGVGKKQYSETVLRNQTDVSQYIQYATVPQALEALKKGEIDLLFEN 180 + I ++ L ++K+GV K Y+ET+L+ + + Y+ + T+ AL +G++D + + Sbjct: 121 FNKVITVNNLASFKIGVMKSDYTETLLKERLKIKNYLTFQTIEDEFVALLEGKVDAVIIS 180 Query: 181 QEVVDYLIVEQGLTGNIVRRLSNLYPQDVAYGISKSEPQLVTYINARLDRLQQSGAFEEL 240 QE+ +Y +V+ + +L +++ + +GISK P+LV Y+NARL L ++G F++L Sbjct: 181 QEIANYFLVKNNYADQVEIKLKDIFILESGFGISKRRPELVGYVNARLKELIKNGIFDQL 240 Query: 241 ----YQQYFFTHSENYTSMXXXXXXXXXXXXLFLLVTVIAALRIYIRHLRRTIHSEQAFF 296 + Y + E +F I +R + L++ + + + Sbjct: 241 YYNYFSTYSSYYYEKKNREVVFSILYILFIIIFASSITIFVMRGINKKLQQGKEAYEKYA 300 Query: 297 RDVIEHSGMIVWAVHADKRIIRFNQYAASMTGLKEKDVLGANLDEIPGLSGGXXXXXXXX 356 + ++ +IV ++ II FN++A +TG K+++V+G ++ Sbjct: 301 ELLASNANVIVLTLNLKGEIIFFNRFAEEVTGYKKEEVVGKRWVDLFVPEFRREDAEKLF 360 Query: 357 XXXXYQDYVSNVELKLPDHSPEARYFSFRTALIQGMDTQAEDIFVLVGMDVEECKQNELK 416 + ++N E ++ + + + + +++ E + + G+D+ K+N+ Sbjct: 361 SEIAEKKVLNNYESEIITKNGDTCWIIWNNVVVEN-SYLNEPLIISTGLDITPIKKNQRL 419 Query: 417 LQHSXXXXXXXXXXXXXXXXXXXXXFNKLEASERRFRLASEGSGAYMWELDWESGMYNLS 476 L+ S L+ E R++ E +WE D ++ Sbjct: 420 LEESYEELEETNQELVNTLEILNKQTELLKEEEERYKFIVENISDCIWEFD-------VA 472 Query: 477 ERWYEVMGYTK-----EEINSFED--GVLSIIHPDDQEPARQARQEHLAGLTPIYEIEYR 529 E+ E G K ++IN D L + HPDD + + Q E E R Sbjct: 473 EKRIEFYGNLKDYFETDKINPKIDYYAWLELYHPDDIKAVMEKIQRAFELRDEKIEYEAR 532 Query: 530 MRTKDNRYVWFEVRGKAIVDPKDKIVLFLGSLIDISKRKQAEFQLGNSYQELEATYEQLT 589 ++ K+ Y W V K D + K +G ID S +K+ E Sbjct: 533 IKDKNGNYKWVSVHIKVFYDNRGKPEKLIGINIDYSAKKEYE------------------ 574 Query: 590 ATQEELVGQYDMLLENQKNMHRLAYMDSLSSLPNRILLLDTMESYFHRP---GGKAALLF 646 + LAY D L++LPNR L + + + G A++ Sbjct: 575 -----------------DRIKYLAYYDDLTNLPNRKLFENKLSELIKKAAQTGKIGAVIL 617 Query: 647 VDTDNFKYINDTLGHKSGDILIRQASERLQSVMREGDM---LSRLGGDEFVVFIKDVEDR 703 +D DNFK IND GH+ GD +R S+++ ++ ++ SR+GGDEF + + +E + Sbjct: 618 IDIDNFKDINDLYGHEVGDECLRTISQKIAEYLKGLEVQNYFSRVGGDEFAIILNGLEKK 677 Query: 704 AEVLNLAESILRSFRRSFLIG--ESNLYISVSIGISFYPEDGETTEEILMNADVAMYRAK 761 V+ + I + F + E LY ++S+GISFYP+DG T+EIL N D+A+ AK Sbjct: 678 DFVIEVCTEIQKIFENEIFLEKIERGLYTTISMGISFYPDDGRDTKEILRNVDMALSLAK 737 Query: 762 EEGKNTFVVYDKSMHMSFNERMNIEKHLRSAMNNNEFELHYQPQVEIKTGLITGFEALIR 821 E GKN F ++ + + ++ IEK+LR A+ N+EF L+YQP V ++ I EALIR Sbjct: 738 ENGKNDFQIFMPFLLLKNLNKIEIEKNLRKAIENDEFVLYYQPVVNLENMEIHSVEALIR 797 Query: 822 WNSPVLGFVSPLSFIKIAEDSRLIIYIGEWVLREASAFMKSMNDRTGLPYKISVNISIIQ 881 W P G VSPL FI +AE+S LI+ IGE V+ +A +K + I++N+S Q Sbjct: 798 WFLPHKGMVSPLEFIPVAEESGLIVRIGEMVIEKALKDLKDWERKGINDIHIAINLSARQ 857 Query: 882 LLQDDFVDIVLDSLEESGLAPNCLELEITESIFMESFENTVSKLEFLKSRGIRIALDDFG 941 F + V LE+ + P + EITE+ +E+F+ ++ L FL GI+ +DDFG Sbjct: 858 FKTKYFENTVAKLLEKYSVDPVKVSFEITETGAVENFDVSLKILGFLCQMGIKFLIDDFG 917 Query: 942 TGYSSLSYLQQLPISTLKMDKIFIDSLADQGYSQSFVQTIIILGHKMGLDVVAEGVEDAD 1001 TGYSSL YL++LPIS +K+DK FI L S++ V+ II++ HK+GL VVAEG+E+ Sbjct: 918 TGYSSLIYLRKLPISGVKIDKSFISELMFSKESRAIVEGIILMAHKLGLKVVAEGIENNK 977 Query: 1002 QLAFLKEADCDKVQGYLISRPVPQRGVIELL 1032 QL LKE CD QGYL S+PVP+ V + L Sbjct: 978 QLEILKEIGCDFGQGYLFSKPVPKEEVEKFL 1008 >B8I783.1 B8I783_CLOCE Diguanylate cyclase/phosphodiesterase Length = 856 Score = 449 bits (1156), Expect = e-124, Method: Compositional matrix adjust. Identities = 231/477 (48%), Positives = 324/477 (67%), Gaps = 8/477 (1%) Query: 564 ISKRKQAEFQLGNSYQELEATYEQLTATQEELVGQYDMLLENQKNMHR-------LAYMD 616 I K + QL S +EL TYE+L A+ EEL Q D + QK++ + +A D Sbjct: 378 IRKIRNIRKQLYLSNEELTQTYEELVASDEELRHQLDEIRSIQKSLSQSEEKYNFMALHD 437 Query: 617 SLSSLPNRILLLDTMESYFH-RPGGKAALLFVDTDNFKYINDTLGHKSGDILIRQASERL 675 L+ LPNR LL+ + G K LLF+D DNFKYINDT+GH+ GD LI +A +RL Sbjct: 438 VLTGLPNRRSLLEDSSRFLGINTGKKTVLLFIDMDNFKYINDTMGHEFGDELINKAGQRL 497 Query: 676 QSVMREGDMLSRLGGDEFVVFIKDVEDRAEVLNLAESILRSFRRSFLIGESNLYISVSIG 735 ++ +++ L RLGGDEF++ I ++E++ E + +L+SF+ F IG S L+I+ SIG Sbjct: 498 KTALKDLGTLYRLGGDEFILLIYNIENQFEAEDFMSQVLQSFKDEFEIGNSVLHITFSIG 557 Query: 736 ISFYPEDGETTEEILMNADVAMYRAKEEGKNTFVVYDKSMHMSFNERMNIEKHLRSAMNN 795 + YP+ G E+++ AD+AMY+AKE+GKN +V+YD+ M +F+ERM IEK L +AM+N Sbjct: 558 AALYPDHGNNIEDLIKCADIAMYKAKEQGKNRYVLYDRDMDKAFSERMTIEKLLHTAMDN 617 Query: 796 NEFELHYQPQVEIKTGLITGFEALIRWNSPVLGFVSPLSFIKIAEDSRLIIYIGEWVLRE 855 NEFE++YQPQ ++++ ITG EAL+RW S LG VSP+ FIK+AED+ LII +GEWVL + Sbjct: 618 NEFEVYYQPQFDLQSQKITGLEALLRWKSSELGNVSPIKFIKVAEDTHLIIPLGEWVLNQ 677 Query: 856 ASAFMKSMNDRTGLPYKISVNISIIQLLQDDFVDIVLDSLEESGLAPNCLELEITESIFM 915 A AF+K ++++ +SVNIS IQ+LQ F ++D + L P CLELEITE+I + Sbjct: 678 ACAFVKELHEKGLQGLTVSVNISTIQILQSGFTRKIIDIINSHKLNPECLELEITETILI 737 Query: 916 ESFENTVSKLEFLKSRGIRIALDDFGTGYSSLSYLQQLPISTLKMDKIFIDSLADQGYSQ 975 ESF KL LK GIRIALDDFG GYSSL+YL+QLPISTLK+DK FIDS++ + Sbjct: 738 ESFTTVFRKLNKLKKMGIRIALDDFGKGYSSLNYLKQLPISTLKIDKSFIDSVSIDEEGR 797 Query: 976 SFVQTIIILGHKMGLDVVAEGVEDADQLAFLKEADCDKVQGYLISRPVPQRGVIELL 1032 + + II LG +G+ ++AEGVE +QL +LK+ CD++QGYL S+P+P V +LL Sbjct: 798 TITRHIITLGKSLGMTIIAEGVEFNEQLEYLKKYHCDRIQGYLFSKPLPGEDVKKLL 854 >Q3AAV9.1 Q3AAV9_CARHZ Sensory box/GGDEF domain/EAL domain protein Length = 769 Score = 432 bits (1112), Expect = e-119, Method: Compositional matrix adjust. Identities = 230/594 (38%), Positives = 348/594 (58%), Gaps = 39/594 (6%) Query: 443 NKLEASERRFRLASEGSGAYMWELDWESGMYNLSERWYEVMGYTKEEINSFEDGVLSIIH 502 ++L+ SE R+RL EG+ +W+ D E+ +SERW +++G+ KE IN++ + + IH Sbjct: 198 DELKKSEERYRLVVEGASDGLWDWDLETDTAYISERWRDLIGFDKEVINNYCETWIKFIH 257 Query: 503 PDDQEPARQARQEHLAGLTPIYEIEYRMRTKDNRYVWFEVRGKAIVDPKDKIVLFLGSLI 562 P D + + HL TP Y EYR++TKD +Y+W RGKA+ + + K + GS Sbjct: 258 PRDVKAVINNLRNHLEKKTPFYLCEYRIKTKDGKYIWILSRGKALWNKEGKAIRMAGSHT 317 Query: 563 DISKRKQAEFQLGNSYQELEATYEQLTATQEELVGQYDMLLENQKNMHRLAYMDSLSSLP 622 DI++RKQ E +L +Y +A+ D L++LP Sbjct: 318 DITQRKQMESKL-----------------------EY------------MAFHDPLTNLP 342 Query: 623 NRILLLDTMESYF---HRPGGKAALLFVDTDNFKYINDTLGHKSGDILIRQASERLQSVM 679 R + L+ ++ R G K A+ FVD DNFK IND+LGH +GD L+++ ++ L + Sbjct: 343 RRDVFLERLKVAMADARRNGKKLAVFFVDLDNFKIINDSLGHHTGDRLLKKIAKELTKCV 402 Query: 680 REGDMLSRLGGDEFVVFIKDVEDRAEVLNLAESILRSFRRSFLIGESNLYISVSIGISFY 739 RE D +SR+GGDEF++ + DV + +A+ IL F + + L +++SIGI+ Y Sbjct: 403 RETDTISRVGGDEFIILLPDVNSIEDTDKVAKRILELFDQPIKLNNYELPVTISIGIAIY 462 Query: 740 PEDGETTEEILMNADVAMYRAKEEGKNTFVVYDKSMHMSFNERMNIEKHLRSAMNNNEFE 799 P+ G++ IL NAD+AMY AK +GKN F +D +M +++ LR A+ N+F Sbjct: 463 PDHGKSERAILKNADIAMYTAKRKGKNGFQYFDIAMKSEVEFANTVKRDLRLALEKNQFI 522 Query: 800 LHYQPQVEIKTGLITGFEALIRWNSPVLGFVSPLSFIKIAEDSRLIIYIGEWVLREASAF 859 L+YQP +++KTG I EAL+RW P G +SP FI IAE++R II IGEWVLR A Sbjct: 523 LYYQPLIDLKTGKIASMEALLRWQHPKKGMISPFHFIPIAEETRQIISIGEWVLRTACRQ 582 Query: 860 MKSMNDRTGLPYKISVNISIIQLLQDDFVDIVLDSLEESGLAPNCLELEITESIFMESFE 919 MK + +SVN+S+ QL Q +F +V D L+E L P LELEITE++ +E+ E Sbjct: 583 MKEWLGMGYSGFSVSVNVSVHQLEQPNFAKVVCDILKEIELEPRYLELEITETVLIEAVE 642 Query: 920 NTVSKLEFLKSRGIRIALDDFGTGYSSLSYLQQLPISTLKMDKIFIDSLADQGYSQSFVQ 979 V L LK G++I +DDFGT SS Y+Q+ + LK+D+ F++ + +++ + Sbjct: 643 TVVENLYHLKKAGVKIIIDDFGTENSSFRYMQKFTVDGLKIDRSFVNGIK-IDVNKAIID 701 Query: 980 TIIILGHKMGLDVVAEGVEDADQLAFLKEADCDKVQGYLISRPVPQRGVIELLE 1033 II+LGH++ L V AEGVE +QL L E+ CDKVQG+ S+P+P VI L++ Sbjct: 702 AIILLGHRLKLPVTAEGVETREQLECLIESGCDKVQGFYFSKPLPPDEVIHLVQ 755 >Q8RAV9.1 Q8RAV9_THETN Diguanylate cyclase/phosphodiesterase domain 2 (EAL) Length = 793 Score = 432 bits (1110), Expect = e-118, Method: Compositional matrix adjust. Identities = 229/596 (38%), Positives = 342/596 (57%), Gaps = 39/596 (6%) Query: 443 NKLEASERRFRLASEGSGAYMWELDWESGMYNLSERWYEVMGYTKEEINSFEDGVLSIIH 502 ++L+ SE R+RL EG+ +W+ D + +SERW +++G KE +N++ + + IH Sbjct: 198 DELKRSEERYRLVVEGASDGLWDWDLITDTAYISERWKDIIGLDKEVVNNYYETWIKFIH 257 Query: 503 PDDQEPARQARQEHLAGLTPIYEIEYRMRTKDNRYVWFEVRGKAIVDPKDKIVLFLGSLI 562 P D + + HL TP Y EYR++TKD RY+W RGKA+ D + + + GS Sbjct: 258 PRDIKIVINNLRNHLEKKTPFYLCEYRIKTKDGRYIWVLSRGKALWDEEGRAIRIAGSHT 317 Query: 563 DISKRKQAEFQLGNSYQELEATYEQLTATQEELVGQYDMLLENQKNMHRLAYMDSLSSLP 622 DI++RKQ E +L +Y +A+ D L+ LP Sbjct: 318 DITERKQMESKL-----------------------KY------------MAFYDPLTGLP 342 Query: 623 NRILLLDTME---SYFHRPGGKAALLFVDTDNFKYINDTLGHKSGDILIRQASERLQSVM 679 R + +D ++ + R G K A+ FVD DNFK IND+LGH GD L+++ + +L++ + Sbjct: 343 RREVFMDRLKIAMADAKRNGKKLAVFFVDLDNFKTINDSLGHHIGDRLLKKVARKLKACL 402 Query: 680 REGDMLSRLGGDEFVVFIKDVEDRAEVLNLAESILRSFRRSFLIGESNLYISVSIGISFY 739 RE D +SR+GGDEFV+ + D+ + + +A IL F + LY+++SIGI+ Y Sbjct: 403 RESDTVSRVGGDEFVILLPDIINIDDTNKVANRILELFNQPIKFNNYELYVTISIGIAIY 462 Query: 740 PEDGETTEEILMNADVAMYRAKEEGKNTFVVYDKSMHMSFNERMNIEKHLRSAMNNNEFE 799 P+ G+ I+ NAD+AMY+AK +GKN+F +D I + LR A+ +F Sbjct: 463 PDHGKNERAIVKNADIAMYKAKRDGKNSFQYFDSITKKEVEIASTIRRDLRFALEKGQFF 522 Query: 800 LHYQPQVEIKTGLITGFEALIRWNSPVLGFVSPLSFIKIAEDSRLIIYIGEWVLREASAF 859 LHYQP V+ +TG + EAL+RW P G +SP+ FI IAE++R II IGEWVLR A Sbjct: 523 LHYQPIVDARTGKVVSMEALLRWQHPKKGLISPIHFIPIAEETRQIISIGEWVLRTACKQ 582 Query: 860 MKSMNDRTGLPYKISVNISIIQLLQDDFVDIVLDSLEESGLAPNCLELEITESIFMESFE 919 MK + + +SVN+S+ QL Q DF +V D L E L P LELEITE++ +E+ + Sbjct: 583 MKEWRNMGYYGFSVSVNVSVHQLQQPDFAKVVFDILNEIELEPRFLELEITETVLIEAMD 642 Query: 920 NTVSKLEFLKSRGIRIALDDFGTGYSSLSYLQQLPISTLKMDKIFIDSLADQGYSQSFVQ 979 V L LK G++I +DDFGT SS YLQ+ + LK+D+ F+ + + +++ V Sbjct: 643 TVVRNLYRLKEMGVKIIIDDFGTENSSFKYLQKFTVDGLKIDRSFVSEIKVE-VNKAIVD 701 Query: 980 TIIILGHKMGLDVVAEGVEDADQLAFLKEADCDKVQGYLISRPVPQRGVIELLEPQ 1035 I LGH+M L V AEGVE +QL L E+ CDKVQGY S+P+P I +++ + Sbjct: 702 AITFLGHRMKLGVTAEGVETKEQLDCLVESGCDKVQGYYFSKPLPPDEAIRMVQKE 757 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.319 0.136 0.386 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 5,777,078,778 Number of extensions: 238276847 Number of successful extensions: 708667 Number of sequences better than 1.0e-05: 20198 Number of HSP's gapped: 683696 Number of HSP's successfully gapped: 20638 Length of query: 1044 Length of database: 3,060,696,203 Length adjustment: 146 Effective length of query: 898 Effective length of database: 1,685,228,013 Effective search space: 1513334755674 Effective search space used: 1513334755674 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 137 (57.4 bits)