BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0459.0002.p (349 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9U6K9.1 A9U6K9_PHYPA Predicted protein (Fragment) 211 8e-53 A8W114.1 A8W114_9BACI Response regulator receiver protein 198 7e-49 B7DQ24.1 B7DQ24_9BACL Diguanylate cyclase 172 3e-41 C1PUV7.1 C1PUV7_ALIAC Diguanylate cyclase (GGDEF) domain-contain... 170 2e-40 O66451.1 O66451_AQUAE Putative uncharacterized protein 129 3e-28 >A9U6K9.1 A9U6K9_PHYPA Predicted protein (Fragment) Length = 866 Score = 211 bits (537), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 112/261 (42%), Positives = 166/261 (63%), Gaps = 11/261 (4%) Query: 94 LIMLIPLLVSMLYLRSTYLKA-TSILCVTYMILLLLDTSVYDNSLR----IQNMIIAFIL 148 + +L+P+L+S++Y L S+ + Y ++ L + S+Y ++ IQ++ I I+ Sbjct: 1 MALLLPVLISVVYFDRKLLYGFGSLTILLYCLIYLTERSLYQKPIQEFIQIQSVFIVSIM 60 Query: 149 TGTALAGFALIARGRDLMQSLESSLKSEQDLRIQNIIMDRLSKVDPLTELYNHKTFHEYL 208 G ++ R ++ M+ LES +KSEQ L ++ I D+L K+D LT LYNHK FHEYL Sbjct: 61 IG-----HTILVRVKEFMRHLESVMKSEQQLLVERTISDKLLKIDALTGLYNHKAFHEYL 115 Query: 209 GWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGHWVGDIVLRQVAGIVLKHIGADDFAARY 268 L+E + P+QLA++DIDNFKKVND YGH VGD+VL++VA V+ + +DFAARY Sbjct: 116 EALLEQCEKYQLPLQLAIIDIDNFKKVNDNYGHRVGDVVLKEVASKVMSTMTPNDFAARY 175 Query: 269 GGEEFVVILTAKPLEDSRRIMTQILHGIAALPVAEMDGNSVTVSIGMHDYAGTDSKSSTF 328 GGEEF +I+ K LE++ R+ Q+ IA + VTVSIG+ ++ D K S F Sbjct: 176 GGEEFAIIMADKTLEEAERMAEQLRERIARTELPHT-VKPVTVSIGLCNFQQGDDKESLF 234 Query: 329 QQADDALYEAKKTGKNKIVVV 349 ++AD ALY+AK+TGKNK+V Sbjct: 235 RKADMALYQAKRTGKNKVVTA 255 >A8W114.1 A8W114_9BACI Response regulator receiver protein Length = 368 Score = 198 bits (503), Expect = 7e-49, Method: Compositional matrix adjust. Identities = 118/309 (38%), Positives = 178/309 (57%), Gaps = 12/309 (3%) Query: 44 PDIMILGTLLVLEAIYKWRPLLSEISNVAASHLIAIVMILNLSDVFYVKPLIMLIPLLVS 103 P + + LL+ IYK + +E + L+A ++I + + PLI+L+P+++S Sbjct: 61 PTVAQVILLLITTVIYKKKITENEYILMVVGSLLAFILIAANTSL-AGAPLILLLPMMIS 119 Query: 104 MLYLRS-----TYLKATSILCVTYMILLLLDTSVYDNSLRIQNMI-IAFILTGTALAGFA 157 +L+ +YL +++ I L D Y LRI I +I + + A Sbjct: 120 ILFFNKNVVIFSYL--VNVIAYLVTIALFPDLGEY---LRIYEFIAYIYIFSAGFIILLA 174 Query: 158 LIARGRDLMQSLESSLKSEQDLRIQNIIMDRLSKVDPLTELYNHKTFHEYLGWLIEHQQS 217 + R ++++ L + EQ+L ++N IM+RLSKVD T LYNHKTF EYL +L E + Sbjct: 175 VQERSDEVIELLRKKVDQEQELMVRNTIMERLSKVDAPTGLYNHKTFQEYLAYLFEQSST 234 Query: 218 NPFPMQLAVLDIDNFKKVNDQYGHWVGDIVLRQVAGIVLKHIGADDFAARYGGEEFVVIL 277 + + QLA+LDIDNFK+VND YGH VGD +L ++AGI+ ++ A+D A+RYGGEEF V+ Sbjct: 235 SSYRFQLAMLDIDNFKQVNDTYGHAVGDKILERIAGIIQANVDANDIASRYGGEEFGVLF 294 Query: 278 TAKPLEDSRRIMTQILHGIAALPVAEMDGNSVTVSIGMHDYAGTDSKSSTFQQADDALYE 337 T E + ++ I I LP EM G +VTVSIG+ +Y + F++AD LY Sbjct: 295 TDCSFETALHVVETIRLEIERLPHEEMGGRNVTVSIGLVEYTDEEQAPVLFEKADTLLYL 354 Query: 338 AKKTGKNKI 346 AKK GKN+I Sbjct: 355 AKKNGKNRI 363 >B7DQ24.1 B7DQ24_9BACL Diguanylate cyclase Length = 376 Score = 172 bits (437), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 114/344 (33%), Positives = 184/344 (53%), Gaps = 16/344 (4%) Query: 20 ISLSMQGDDPRLSGKSYLFGNVLLP----DIMILGTLLV-LEAIYKWR----PLLSEISN 70 ++L + GD L G+ +L LLP M LLV +E +W P E Sbjct: 27 VALFLAGDLLFLPGEWWLHRAHLLPLALRAWMFAPILLVSIEGAAEWAVRKYPQSRENVL 86 Query: 71 VAASHLIAIVMILNLSDVFYVKPLIMLIPLLVSMLYLR--STYLKATSILCVTYMILLLL 128 + A L+A+V I D ++ +L+P++ S+L+LR +L + L+ Sbjct: 87 IVAGTLLALVAIAAYPDAEALRA-SLLLPVVTSILHLRVEKVWLAGAVAFAAELALTLMQ 145 Query: 129 DTSVYDNSLRIQNM----IIAFILTGTALAGFALIARGRDLMQSLESSLKSEQDLRIQNI 184 + +Q++ + + +L T A ++ G + L +++ +L ++ I Sbjct: 146 MSGGASAEAILQSLGHLALWSLVLLWTTSACHIVLRFGLRIWDELRVQARAQTELWVRQI 205 Query: 185 IMDRLSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGHWVG 244 + ++ +K D LT LYN K+F EYL + ++ + P+ LAV+DIDNFK++ND+YGH VG Sbjct: 206 LSEKEAKTDALTGLYNRKSFDEYLDFALQISEGTNTPLHLAVIDIDNFKQINDRYGHLVG 265 Query: 245 DIVLRQVAGIVLKHIGADDFAARYGGEEFVVILTAKPLEDSRRIMTQILHGIAALPVAEM 304 D +LR+ A + +H+ A DF ARYGGEEF VI+ E + + M +I IA + E+ Sbjct: 266 DEILRRTAQAIQQHLAAGDFLARYGGEEFAVIIPEVSHEQAVQNMEKIREYIANVHHLEL 325 Query: 305 DGNSVTVSIGMHDYAGTDSKSSTFQQADDALYEAKKTGKNKIVV 348 DGN TVSIG+ + +++ F++AD LY AK+TGKNKIV Sbjct: 326 DGNRATVSIGLSTHRPGETRDELFERADQCLYRAKQTGKNKIVA 369 >C1PUV7.1 C1PUV7_ALIAC Diguanylate cyclase (GGDEF) domain-containing protein Length = 402 Score = 170 bits (431), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 111/344 (32%), Positives = 184/344 (53%), Gaps = 16/344 (4%) Query: 20 ISLSMQGDDPRLSGKSYLFGNVLLP-----DIMILGTLLVLEAIYKW----RPLLSEISN 70 ++L + GD L G+ +L LLP + ++ ++ +W P E Sbjct: 53 VALFLAGDLLFLPGEWWLHRAHLLPLALRAWVFAPLAMVCIQGAAEWSVRKHPQSRENML 112 Query: 71 VAASHLIAIVMILNLSDVFYVKPLIMLIPLLVSMLYLR--STYLKATSILCVTYMILLLL 128 +A+ L+A+V I + +L+P++ S+L+LR +L + ++ L+ Sbjct: 113 IASGTLLALVAIAAYPGAESLCA-SLLLPIVTSILHLRVEKVWLAGAAAFAAELVLTLMQ 171 Query: 129 DTSVYDNSLRIQNM----IIAFILTGTALAGFALIARGRDLMQSLESSLKSEQDLRIQNI 184 +S +Q++ + + IL T A ++ G + L +++ +L ++ I Sbjct: 172 LSSSASAQAILQSLGHLALWSLILLWTTAASHIVLRFGLRIWDELRVQTRAQTELWVRQI 231 Query: 185 IMDRLSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGHWVG 244 + ++ +K D LT LYN K+F EYL + ++ P+ LAV+DIDNFK++NDQYGH VG Sbjct: 232 LSEKEAKTDALTGLYNRKSFDEYLDFALQISDGTNTPLHLAVIDIDNFKQINDQYGHLVG 291 Query: 245 DIVLRQVAGIVLKHIGADDFAARYGGEEFVVILTAKPLEDSRRIMTQILHGIAALPVAEM 304 D +LR+ A + +H+ A DF ARYGGEEF VI+ E + + M +I IA + E+ Sbjct: 292 DEILRRTAQAIQQHLAAGDFLARYGGEEFAVIIPEVTHEQAVQNMEKIREYIANVHHVEL 351 Query: 305 DGNSVTVSIGMHDYAGTDSKSSTFQQADDALYEAKKTGKNKIVV 348 DGN TVSIG+ + +++ F++AD LY AK+TGKNKIV Sbjct: 352 DGNRATVSIGLSTHRPGETRDELFERADQCLYRAKQTGKNKIVA 395 >O66451.1 O66451_AQUAE Putative uncharacterized protein Length = 431 Score = 129 bits (325), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 64/169 (37%), Positives = 102/169 (60%), Gaps = 2/169 (1%) Query: 182 QNIIMDRLSKVDPLTELYNHKTFHEYLGWLIEHQQSNPFPMQLAVLDIDNFKKVNDQYGH 241 + + +R++ DPLT LYN + F E + + + + ++DIDNFKK+ND YGH Sbjct: 256 EKTLYERMALTDPLTGLYNRRVFTEMAEKELAKAKRYGYNFSILMIDIDNFKKINDTYGH 315 Query: 242 WVGDIVLRQVAGIVLKHIGADDFAARYGGEEFVVILTAKPLEDSRRIMTQILHGIAALPV 301 VGD+VL++++ I+ +++ D AR+GGEEF+V+L+ L + + Q+ I P+ Sbjct: 316 DVGDLVLKKISEILKRNVRGADLVARFGGEEFIVMLSNTNLNGAVKKAEQLRRMIEQTPI 375 Query: 302 AEMDGNS--VTVSIGMHDYAGTDSKSSTFQQADDALYEAKKTGKNKIVV 348 +G VTVSIG+ Y G +S ++AD ALYEAK+ GKN++ V Sbjct: 376 ELPNGEKLRVTVSIGVSTYRGHESLEELIKEADQALYEAKRKGKNRVEV 424 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.138 0.396 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,825,006,097 Number of extensions: 70556415 Number of successful extensions: 229135 Number of sequences better than 1.0e-05: 13523 Number of HSP's gapped: 216878 Number of HSP's successfully gapped: 13538 Length of query: 349 Length of database: 3,060,696,203 Length adjustment: 136 Effective length of query: 213 Effective length of database: 1,779,438,163 Effective search space: 379020328719 Effective search space used: 379020328719 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 132 (55.5 bits)