BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0455.0004.p (501 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value A9U762.1 A9U762_PHYPA Predicted protein (Fragment) 567 e-159 B3K8H8.1 B3K8H8_9BACI Platelet-activating factor acetylhydrolase... 339 4e-91 Q5YXG3.1 Q5YXG3_NOCFA Putative uncharacterized protein 297 2e-78 B8I4R5.1 B8I4R5_CLOCE Platelet-activating factor acetylhydrolase... 249 5e-64 Q5WC78.1 Q5WC78_BACSK Carboxylic ester hydrolase EC=3.1.1.- 241 1e-61 >A9U762.1 A9U762_PHYPA Predicted protein (Fragment) Length = 312 Score = 567 bits (1461), Expect = e-159, Method: Compositional matrix adjust. Identities = 268/307 (87%), Positives = 283/307 (92%) Query: 150 MVQVWYPAQAGTGRYAPFIPDTPILRYMAANYGLPGFTFQHLKYVSSHAYSGAEVSSAQT 209 MVQVWYPAQAGTG+YAPFIP+TPILRYMAANYGLPGFTFQHLKYVSSHAYSGAE+SSAQT Sbjct: 1 MVQVWYPAQAGTGKYAPFIPNTPILRYMAANYGLPGFTFQHLKYVSSHAYSGAEISSAQT 60 Query: 210 SYPLILANPGNGSSRFLHTSQAENLASHGYIVAVIDHTYNTFATEFPDGRVTTSTTDDLF 269 SYPLILANPGNGSSRFLHTSQAENLASHGYIVAVIDHT+NT ATEFPDGR+TTSTTD+LF Sbjct: 61 SYPLILANPGNGSSRFLHTSQAENLASHGYIVAVIDHTFNTIATEFPDGRITTSTTDNLF 120 Query: 270 SPDHDYRTESGNRDKLGKVLTDDVVFVLDQFELIQSGQISSDFKGRIDLGHVGVFGHSIG 329 SPDHDY TE NRDKLGKVLTDDV FVLDQFELIQSGQI S GRIDLGHVGVFGHSIG Sbjct: 121 SPDHDYATERENRDKLGKVLTDDVAFVLDQFELIQSGQIPSQLHGRIDLGHVGVFGHSIG 180 Query: 330 GATAYDASYDPRITVGIDLDGGLYRLRDREGLRKPFLFINSESEFERLKMVMDNRVYTDA 389 GATAYDA+YDPRI GIDLDGGLYRLRD+EGLRKPFLFINSES FE+L VM+N+VY+D Sbjct: 181 GATAYDAAYDPRIAAGIDLDGGLYRLRDKEGLRKPFLFINSESYFEQLTRVMNNQVYSDE 240 Query: 390 ELKRMGSTREWNDQVTEDKKLELERMRETVGEGGQFLYIEKTEHLNFTDVQFISPIFKML 449 EL RMGSTREW DQV DKK+ELERMRET EGGQ LYIE TEHLNFTD+QFISPIFK+L Sbjct: 241 ELNRMGSTREWEDQVAADKKVELERMRETAEEGGQVLYIENTEHLNFTDIQFISPIFKIL 300 Query: 450 GITGKIA 456 GITGK A Sbjct: 301 GITGKCA 307 >B3K8H8.1 B3K8H8_9BACI Platelet-activating factor acetylhydrolase plasma/intracellular isoform II Length = 501 Score = 339 bits (869), Expect = 4e-91, Method: Compositional matrix adjust. Identities = 204/512 (39%), Positives = 288/512 (56%), Gaps = 37/512 (7%) Query: 1 VRFFEILLFFSSVCLLALLFIFNQRIRRPALLLTSGAGSIFLVIHLLVEGYRVQLLFLYG 60 +R E+L + V +L +L N I R A + AG + + LLVEGYR Q++ Y Sbjct: 1 MRVLEMLWVAACVAMLIILLSRNT-INRKAGAIVCIAGGLLFAVQLLVEGYRWQMIPAYI 59 Query: 61 FTVLMLLLSLRDVFITPKVVRTASRIRRVLGRLFIVF--GLIATSCFLYVFPVFDLPAPT 118 T L+ +L V + V+ +R + L +V G +A S L PVF LP P+ Sbjct: 60 VTALLFVL----VLFKRRTVKKP--LRYTIWGLSVVLLGGSVALSALL---PVFHLPKPS 110 Query: 119 GELKVGTQVFHFTDPSREETFGTTATGKRELMVQVWYPAQAG--TGRYAPFIPDTPIL-- 174 GE +VGT HF D REETF KREL+VQVWYPA A A P L Sbjct: 111 GEFRVGTDTLHFVDADREETFTEQKGDKRELIVQVWYPAAASGHDAEKATVFPKDKRLFH 170 Query: 175 RYMAAN---YGLPGFTFQHLKYVSSHAYSGAEVSSAQTSYPLILANPGNGSSRFLHTSQA 231 YM A GLP + KY ++A A++ A+ YP++L + G G R LH+SQA Sbjct: 171 TYMQAYSEYLGLPAAALDYWKYSRANANGHADLRLAENPYPVVLLSHGMGVGRILHSSQA 230 Query: 232 ENLASHGYIVAVIDHTYNTFATEFPDGRV----TTSTTDDLFSPDHDYRTESGNRDKLGK 287 E+LASHGYIV IDHTY+T AT FPDGRV T + + LF D RT + K Sbjct: 231 EHLASHGYIVFAIDHTYSTAATAFPDGRVTGFLTEQSQERLFE---DSRT-------ILK 280 Query: 288 VLTDDVVFVLDQFELIQSGQISSDFKGRIDLGHVGVFGHSIGGATAYDASY-DPRITVGI 346 V +D+ FV DQ E +QSG ++S FKG +DL ++G+ GHS GGA A++A Y +PRI G+ Sbjct: 281 VWNEDIAFVTDQLERLQSGAVASKFKGALDLDNIGMMGHSFGGAAAFEAVYSNPRIKAGV 340 Query: 347 DLDGGLYRLRDREGLRKPFLFINSES--EFERLKMVMDNRVYTDAELKRMGSTREWNDQV 404 ++DG L+ +DR+ + KPF+F+ SE + + T+AEL+ +G TRE D + Sbjct: 341 NMDGTLFITKDRDDMEKPFMFMESEDFMKVNEQQAKYRQTPATEAELQALGLTREQFDMI 400 Query: 405 TEDKKLELERMRETVGEG-GQFLYIEKTEHLNFTDVQFISPIFKMLGITGKIAPERADSI 463 +++LEL+ M +G G+ +YIE H NFTD+Q SP+ ++ G+TG + R I Sbjct: 401 LANRELELKLMDRLSQQGLGRTVYIEGAGHYNFTDLQLYSPLTRLTGMTGSMNGSRGAEI 460 Query: 464 INAYMLDFFDMYLKNQGGSLMKGPDSRFPEVK 495 +N Y+L+FF+ +L+ L+ GP +PEVK Sbjct: 461 VNRYVLEFFNQHLRGMESKLLTGPSEEYPEVK 492 >Q5YXG3.1 Q5YXG3_NOCFA Putative uncharacterized protein Length = 412 Score = 297 bits (760), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 177/393 (45%), Positives = 230/393 (58%), Gaps = 13/393 (3%) Query: 108 VFPVFDLPAPTGELKVGTQVFHFTDPSREETFGTTATGKRELMVQVWYPAQAGTGRYAPF 167 VFP F LPAPTG VGT H D R E FG T RELMVQVWYPA+ G AP Sbjct: 28 VFPTFRLPAPTGAHPVGTTTLHLVDAERREVFGPDPTAPRELMVQVWYPARDTDGSLAPL 87 Query: 168 IPD-TPILRYMAANYGLPGFTFQHLKYVSSHAYSGAEVSSAQTSYPLILANPGNGSSRFL 226 +P T + +A +GLP +L + +HA + ++ + +P++L N G GS+RF Sbjct: 88 VPGGTAVTEQIARGFGLPARGLDYLTEIPTHARANVPIADSGHPFPVVLLNHGYGSARFY 147 Query: 227 HTSQAENLASHGYIVAVIDHTYNTFATEFPDGRVTTSTTDDLFSPDHDYRTESGNRDKLG 286 HTS AE+LA+HGY V IDHTY+T AT P GR+ T TD+ + DYR D++G Sbjct: 148 HTSLAEDLAAHGYAVFAIDHTYSTRATALPGGRLATMRTDEDRIGEPDYR------DEVG 201 Query: 287 KVLTDDVVFVLDQFELIQSGQISSDFKGRIDLGHVGVFGHSIGGATAYDASYDPRITVGI 346 +V T DV VLD+ + + F GR+D G VGV GHS GGA AYDA+YDPR+T GI Sbjct: 202 QVWTADVTAVLDRLPALNA---DPRFAGRLDTGRVGVVGHSFGGAAAYDAAYDPRVTTGI 258 Query: 347 DLDGGLYRLRDREGLRKPFLFINSESEFERLKMVMDNRVYTDAELKRMGSTREWNDQVTE 406 DLDG LYR RDR L +PFLF+ SE F+ V VY+DAEL +G++R D+ T Sbjct: 259 DLDGTLYRFRDRAPLAEPFLFVYSEQAFDLYDRVRRGHVYSDAELAELGASRAEVDRDTA 318 Query: 407 DKKLELERMRETVGEGGQFLYIEKTEHLNFTDVQFISPIFKMLGITGKIAPERADSIINA 466 + ELE +R G LY+ T H NF D Q+ SP+ + LG+ G IAPERA +I+N Sbjct: 319 VARRELEHLRAAARAGSPILYVRGTAHNNFMDQQYFSPLLRTLGLIGDIAPERAGAIVND 378 Query: 467 YMLDFFDMYLKNQGGSLMKGPDSRFPEVKIVTS 499 + F L+ G + G R+PE+ VT Sbjct: 379 IVRGFLGAGLRGGGLPDLPG---RYPEIVDVTE 408 >B8I4R5.1 B8I4R5_CLOCE Platelet-activating factor acetylhydrolase plasma/intracellular isoform II Length = 488 Score = 249 bits (635), Expect = 5e-64, Method: Compositional matrix adjust. Identities = 171/503 (33%), Positives = 263/503 (52%), Gaps = 30/503 (5%) Query: 1 VRFFEILLFFSSVCLLALLFIFNQRIRRPALLLTSGAGSIFLVIHLLVEGYRVQLLFLYG 60 +R FEI+L + L L +F+++ + + G + +I + EGYR+Q+L Y Sbjct: 1 MRLFEIVLIIINFFTLGWL-LFSKKNSKKVSCILFGISFVTTLIQIFAEGYRIQVLPAY- 58 Query: 61 FTVLMLLLSLRDVFITPKVVRTASRIRRVLGRLFIVFGLIATSCFLYVFPVFDLPAPTGE 120 + L L++ F+ + R + VLG +F L+ + PVF L PTG Sbjct: 59 ---ICLPLNVLIFFLKGRKPRKTWKF--VLGSIFSFLYLLIAVALPALLPVFSLEKPTGP 113 Query: 121 LKVGTQVFHFTDPSREETFGTTATGKRELMVQVWYPAQAGTG-RYAPFIPD-TPILRYMA 178 +VGT + +TD +R E + KRELMVQVWYPA+ + AP+I D + IL+ Sbjct: 114 YQVGTVTYDWTDENRLEEATKDPSDKRELMVQVWYPAEKTDNLKRAPYIKDLSAILKGGE 173 Query: 179 ANYGLPGFTFQHLKYVSSHAYSGAEVSSAQTSYPLILANPGNGSSRFLHTSQAENLASHG 238 L F HLKYV S++Y+ A++S Q YPL++ + G G+ R +T + E LAS G Sbjct: 174 KTVPLVSFLLSHLKYVKSNSYTDAKLSGKQEKYPLLIFSHGYGAFRNANTFEVEELASQG 233 Query: 239 YIVAVIDHTYNTFATEFPDGRVT--TSTTDDLFSPDHDYRTESGNRDKLGKVLTDDVVFV 296 YIV IDHTY+ AT F DGRV T +F Y DK ++ DV FV Sbjct: 234 YIVVGIDHTYDAAATVFSDGRVAELNQDTQKMF-----YSGSVDAMDKHNEIWVKDVEFV 288 Query: 297 LDQFELIQSGQISSDFKGRIDLGHVGVFGHSIGGA-TAYDASYDPRITVGIDLDGGLY-- 353 LD E I + F G+IDL +G+FGHS GGA TA DPR+ GI++DG LY Sbjct: 289 LDTVEKINKKDPLNHFTGKIDLDKIGMFGHSYGGATTAQVLMRDPRVKAGINMDGYLYGS 348 Query: 354 RLRDREGLRKPFLFINSESEFERLKMVMDNRVYTDAELKRMGSTREWNDQVTEDKKLELE 413 + D G+ KPF+ ++++ + +KM +D + Y D LKR G T + + E ++ Sbjct: 349 SIPD-TGVSKPFMMMDAD---DSMKMFLD-KDYLDKSLKRYGITGDLRKRY-EKSSIKYG 402 Query: 414 RMR-ETVGEGGQFLYIEKTEHLNFTDVQFISPIFKMLGITGKIAPERADSIINAYMLDFF 472 ++R + GG + I+ T+H +F+D+ +SP+ K+ G+ P IIN + L FF Sbjct: 403 KIRSNAIANGGYSMLIKNTDHTSFSDMYLLSPLAKI----GRENPRTVFKIINDFTLTFF 458 Query: 473 DMYLKNQGGSLMKGPDSRFPEVK 495 + YL + ++ ++ ++ Sbjct: 459 NKYLLGDSSASLEDTAKKYKNIE 481 >Q5WC78.1 Q5WC78_BACSK Carboxylic ester hydrolase EC=3.1.1.- Length = 478 Score = 241 bits (615), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 163/501 (32%), Positives = 259/501 (51%), Gaps = 34/501 (6%) Query: 1 VRFFEILLFFSSVCLLALLFIFNQRIRRPALLLTSGAGSIFLVIHLLVEGYRVQLLFLYG 60 +R E++L ++ + L F+ ++ ++ +++ A I V+H++VEG R Q++F Y Sbjct: 1 MRLLELILVVLAIAVF-LWFVVSKTKKQKMIVIGLAALYIVAVLHVMVEGPRWQMVFAY- 58 Query: 61 FTVLMLLLSLRDVFITPKVVRTASRIRRVLGR-LFIVFGLIATSCFLYVFPVFDLPAPTG 119 ++ LL++ +F K R+ +R+ G L V+GL+ + L + PVF PTG Sbjct: 59 --LVPFLLTIGMLF--RKQGRSQNRLLHWGGYGLAAVYGLVMVATPL-LLPVFSFEKPTG 113 Query: 120 ELKVGTQVFHFTDPSREETFGTTATGKRELMVQVWYPAQAGTGRYAPFIPDT-PILRYMA 178 + VGT+ F+ D +RE+ T G RELMVQVWYP+++ G+ AP+ D PI + Sbjct: 114 KYPVGTETFYLKDENREDA--PTIAGGRELMVQVWYPSESQQGKRAPYTKDVGPITEGLE 171 Query: 179 ANYGLPGFTFQHLKYVSSHAYSGAEVSSAQTSYPLILANPGNGSSRFLHTSQAENLASHG 238 +P + HL+YV+++A G++VS +YP+I+ + G R +T Q E LASHG Sbjct: 172 QALSIPAWVLSHLRYVNTYATEGSQVSEKADTYPVIVFSHGMTGFRNQNTFQVEELASHG 231 Query: 239 YIVAVIDHTYNTFATEFPDGRVTTSTTDDLFSPDHDYRTESGNRDKLGKVLTDDVVFVLD 298 YIV IDH ++ AT +PDGR + + L T D + D+ FVLD Sbjct: 232 YIVVGIDHAFDAAATVYPDGRSVLLSENQL--------TGFEQLDAHMDIWVKDISFVLD 283 Query: 299 QFELIQSGQISSDFKGRIDLGHVGVFGHSIGGATAYDA-SYDPRITVGIDLDGGLYRLR- 356 + E I DF+G++DL +G+FGHS GGA A + D R+ V +++DG LY Sbjct: 284 ELEKWNRSGIEGDFEGKLDLEKIGMFGHSYGGAAAAQMLARDSRVKVALNMDGTLYGSEP 343 Query: 357 DREGLRKPFLFINSESEFERLKMVMDNRVYTDAELKRMGSTREWNDQVTEDKKLELERMR 416 G KP+L +N E + K D ++ D + + G +R E E + R Sbjct: 344 PANGFAKPYLQMNGEKSID--KAAFDAKL--DQAVAQTGKSR----ASYEAFWAESQTRR 395 Query: 417 ETVGEGGQF-LYIEKTEHLNFTDVQFISPIFKMLGITGKIAPERADSIINAYMLDFFDMY 475 ET GG + + I T H++FTD SP+ + G E +IN + FFD Y Sbjct: 396 ETALHGGGYTMTIPHTSHMSFTDFHLFSPLLENKGEQ----IEEVHHLINDVSIAFFDEY 451 Query: 476 LKNQGGSLMKGPDSRFPEVKI 496 L + L++ ++ PEV + Sbjct: 452 LAGKATGLLQEQANKHPEVGL 472 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.324 0.141 0.416 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,011,701,769 Number of extensions: 132040910 Number of successful extensions: 305934 Number of sequences better than 1.0e-05: 186 Number of HSP's gapped: 305379 Number of HSP's successfully gapped: 186 Length of query: 501 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 361 Effective length of database: 1,741,754,103 Effective search space: 628773231183 Effective search space used: 628773231183 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 15 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 133 (55.8 bits)