BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0454.0005.p (525 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B8I947.1 B8I947_CLOCE Two component transcriptional regulator, A... 202 8e-50 Q9KDT8.1 Q9KDT8_BACHD BH1123 protein 201 1e-49 B1DAS8.1 B1DAS8_9BACL Two component transcriptional regulator, A... 190 3e-46 B1D5Z5.1 B1D5Z5_9BACL Two component transcriptional regulator, A... 185 1e-44 B3KJG1.1 B3KJG1_9BACI Response regulator receiver 184 2e-44 >B8I947.1 B8I947_CLOCE Two component transcriptional regulator, AraC family Length = 539 Score = 202 bits (514), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 148/545 (27%), Positives = 278/545 (51%), Gaps = 42/545 (7%) Query: 5 ALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVM 64 A++VDDED V GLK+ DW + I I +++G++A ++++ + + D+V TD+ MP M Sbjct: 4 AIIVDDEDLVRQGLKKHFDWSDHNIEIVADLSDGQKAFQYVKDNHV--DLVLTDVLMPYM 61 Query: 65 DGFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVK 124 DG L + L+ KII ++GH++ + K A++ DY+LK ++L+ ++ T+ R+V Sbjct: 62 DGITLAKNLRELYPEIKIIFISGHDDVSYLKNALKVEAVDYILKSIDLDELKDTVSRVVN 121 Query: 125 VIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYE-PELM----CYIGVPM-DAP 178 + TE + + A++E+ LN+ PL+ ER +++ +E P++M ++ +P+ D Sbjct: 122 TMNTENQSKKTMADMENLLNQSFPLLQERFFITMIRDDFENPDIMKERIAFLNIPLNDEM 181 Query: 179 YYQAVIGYTGSSNNTWNIEMESVRQSVSAALRSVGNPVSLAY-------NERG-FILLMS 230 YY ++ + +++ E RQ +S +++ V Y N++G +++++S Sbjct: 182 YYCVLVVQIQRIYSKFHVLTERERQILSLQIQNECTEVGKQYSDTICFENKQGEYVMILS 241 Query: 231 YRSTEEAAEAPLILERVSQELQRKRQIGLNFAQGKPCSEPYQ----IPQSFQEAREML-K 285 E+ E L+ VS+ L ++ +N S+ ++ I S++ A + K Sbjct: 242 L--LEDEYEETLL--EVSENLDKRLNGYMNLPVSIGISDRFKGLENIKASYENASNSISK 297 Query: 286 HKLFSGNTEGQEGSHGLEDSFESGRTMFPRKEKQRLLNAVYACNREQVIGQLEDLQRQYS 345 L + +++S + + + K+ L + + N EQV L +L + Sbjct: 298 RYLLDDELTISVDKYEMDESLKE----YKERAKKSLQECLSSGNTEQVSEVLREL---FH 350 Query: 346 TAQHLYPAGYIRKLSAELIMLLSLILYE-----RNESINQLIPGEPEFVTSIQSQNDPKL 400 + +P + L L++L + I+ + +++ NQ + E +F+ + L Sbjct: 351 IIREKFPDDEEQNLMIFLLLLPTRIVTDIKINKKSDYSNQRMILE-KFLCCADFEEQCLL 409 Query: 401 VFDAVKRLYSLLLDLPVQSEMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPNYLG 460 + ++LY + L + I V I E+I + LA+ V+LTP YL Sbjct: 410 I----QKLYFEVATLMSSMSKTYSHTIINQVRKTIEERFKEQISISTLARDVYLTPTYLC 465 Query: 461 SLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAGIK 520 LFK+ G +DYL R+E AK+LL P ++Y+V +VGY +P YFS+LFK+Y GI Sbjct: 466 VLFKQVTGTTINDYLTLTRLEKAKKLLSDPYIKLYDVCYEVGYLSPSYFSRLFKKYTGIS 525 Query: 521 PSQYK 525 PS+Y+ Sbjct: 526 PSEYR 530 >Q9KDT8.1 Q9KDT8_BACHD BH1123 protein Length = 526 Score = 201 bits (512), Expect = 1e-49, Method: Compositional matrix adjust. Identities = 152/544 (27%), Positives = 260/544 (47%), Gaps = 55/544 (10%) Query: 5 ALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVM 64 +++DDE+ V+ GLK+ I WK G G NGR L+ + + + IV TDI MP+M Sbjct: 4 VVIIDDEEHVVRGLKKIISWKALGCECVGEAANGRRGLDIVRET--SPHIVLTDIYMPIM 61 Query: 65 DGFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVK 124 G + + L+ + ++++L+G+ EFE A+KA++ I DYL KP +++IE + R++ Sbjct: 62 YGLDMIQILREDGFDGEVVILSGYSEFEHARKAMQLNITDYLSKPASVDTIETVLKRVIN 121 Query: 125 VIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLL-----NGTYEPELMCYIGVPMDAPY 179 + ++ Q E+ +++ PL+ + SLL NG E + I D + Sbjct: 122 KLEEKQRQQGYLQELTNKVKRYEPLVETEWMKSLLTGRLRNGEIPEEFLAKITKWKDQQH 181 Query: 180 YQAVIGYTGSSNN-----TWNIEMESVRQSVSAALRSV--GNPVSLAYNE----RGFILL 228 + Y G N W + R SV +R V G P+ Y E R + L Sbjct: 182 IACSLTYDGPQNKELKPADWYL----FRYSVHKMIREVLNGYPIDFRYLEMDAYRSALCL 237 Query: 229 MSYRSTEEAAEAPLILE---RVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLK 285 +S E + +++E +V Q + + G+ + + +SF EA Sbjct: 238 HVNKSVSEPVLSCMLMEIKDQVEQGIYSSFNVKTTVHYGRVKEDWTDLSESFHEA----- 292 Query: 286 HKLFSGNTEGQEGSHGLEDSFESG-RTMFPRKEKQRLLNAVYACNR-------EQVIGQL 337 E Q S L + +E G R FP + Q+L +A+ + E+ +G L Sbjct: 293 ------CMESQ--SFPLGNPYEDGTRATFPMESSQKLYDAIRYADATRAKEVLEEAVGVL 344 Query: 338 EDLQRQYSTAQHLYPAGYIRKLSAELIMLLSLILYERNESINQLIPGEPEFVTSIQSQND 397 ++ YST GY K+ E+ +++ LY+ I ++ + + + Q + Sbjct: 345 GEVP--YSTL-----VGY--KVGIEIWTIITYSLYDIGILIQEMFDEDFDLAQHLTKQGN 395 Query: 398 PKLVFDAVKRLYSLLLDLPVQSEMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPN 457 + + + E K++Q I V+ YI HL E I L+++A +++++ N Sbjct: 396 WQEWIRFLCEQIEHICYHQQWDENIKHKQLIEQVMIYIEKHLAENITLQDIADELYISRN 455 Query: 458 YLGSLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYA 517 YLG +FK+ VG F +Y+ + RME AK+++ + IYEVS+KVGY NP YF+ +FK+Y Sbjct: 456 YLGQIFKKVVGESFKNYVTRLRMEKAKKMIQEGNFLIYEVSEKVGYVNPAYFTTMFKKYT 515 Query: 518 GIKP 521 G P Sbjct: 516 GYTP 519 >B1DAS8.1 B1DAS8_9BACL Two component transcriptional regulator, AraC family Length = 533 Score = 190 bits (483), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 142/544 (26%), Positives = 266/544 (48%), Gaps = 43/544 (7%) Query: 5 ALLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVM 64 L+VDDE + LK ++ W + G IAG NG EALE + S + D+V D+ MP+M Sbjct: 4 VLIVDDEFYFRQALKISLPWSELGFQIAGEAKNGAEALELM--SEVEPDVVLVDMNMPIM 61 Query: 65 DGFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVK 124 DG K + K +VL+GH EF +A++A++ G+ +Y+LKP+ E ++ ++ + + Sbjct: 62 DGLEFIHKAKERDQKTKFLVLSGHSEFAYARQAVQLGVSNYVLKPINEEELQSSLLNIKE 121 Query: 125 VIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTY----EPELMCYIGVPMDAPYY 180 +IR+E+ E ++ + +EG + E++L L G+ + + +G+P + +Y Sbjct: 122 LIRSERLGELELDDLRKQASEGFSFMKEQVLNDWLQGSSRSRPQQNRLHDLGIPQEGLHY 181 Query: 181 QAVIGYTGSS-----NNTWNIEMESVRQSVSAALRSVGNPVSLAYNERGFILLM-----S 230 + V+ + + I V++ ++S + VS E +L++ S Sbjct: 182 RTVVVDLDADEERHPDEGMTIPKAKVQEIAKRCMQSAFHCVSCQDQEGRLVLILGAPEGS 241 Query: 231 YRSTEEAAEAPLILERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHKLFS 290 + + E I +R+ +Q + G C IP S++EA LKH+ Sbjct: 242 FNNLE------TICQRIRLTVQNDTAYTVTIGLGNGCDTYESIPSSYKEAIIALKHRFIW 295 Query: 291 GNTEGQEGSHGLEDSFESGRTMFPRKEKQRLLNAVYACNR----EQVIGQLEDLQRQYST 346 G + S +E ++G ++ +++ LL + NR E ++ +D + Q ++ Sbjct: 296 GGNKVFVHSLKVEPGMKTG--LYSVEKRSGLLMLMRIGNRTETEEWLVRFFQDARVQNAS 353 Query: 347 AQHLYPAGYIRKLSAELIMLLSLILYERNESINQLI--PGEPEFVTSIQSQNDPKLVFDA 404 + L AG E++ L E ++S + +P+ + +Q K + + Sbjct: 354 MEMLLLAG------IEVVSTCLEFLAEASQSFESVFRDTTQPDMIQHVQRM---KTINEL 404 Query: 405 VKRLYSLLLDLPVQSEMKKNRQTIRTVLD---YINNHL-DEEIRLEELAQKVFLTPNYLG 460 + ++ L+L +K + ++ + + YI+NH +EE+R+E++A+ V + N+L Sbjct: 405 EEWIHDLILKAMNHVHSRKTNRAVKVIEEVKAYISNHYGNEELRIEDIARSVHMNYNHLC 464 Query: 461 SLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAGIK 520 +FK+ +DYL + R+ AK L Q I V+ +VGY + +YFSK FK+Y GI Sbjct: 465 FVFKKETTFTINDYLTEIRIIKAKELFDQGEKVIQNVANRVGYADANYFSKCFKKYMGIT 524 Query: 521 PSQY 524 PS+Y Sbjct: 525 PSKY 528 >B1D5Z5.1 B1D5Z5_9BACL Two component transcriptional regulator, AraC family Length = 535 Score = 185 bits (469), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 139/542 (25%), Positives = 266/542 (49%), Gaps = 37/542 (6%) Query: 6 LLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVMD 65 L+VDDE + G++ +IDW+ YGI + G +G E LE + + I TDI+MP+MD Sbjct: 5 LIVDDEPNIRKGIRTSIDWEDYGIEVVGEAADGVEGLE--KALKLKPHITVTDIRMPLMD 62 Query: 66 GFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPV---ELESIELTIDRL 122 G L+ LK+ +I++L+G+E+F FAK+A+ G+ DYLLKPV EL + L + Sbjct: 63 GLELSRHLKNQLPDTRIVILSGYEDFSFAKEALAIGVQDYLLKPVGAEELVDLMLKLSEE 122 Query: 123 VKVIRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYEPELMCY-----IGVPMDA 177 +K+ +K Q + +NE I + +L G + + + + Sbjct: 123 IKLAEADKRNRQS---LNMMINENYQTIKSDFINRILQGGVTDSSAIFDKAELLKIRLSG 179 Query: 178 PYYQAV-IGYTGSSNNTWNIEMESVRQSVSAALRSVGNPVSLA-------YNERGFILLM 229 P Y + I + T ++ E+ R+ + ++ ++ V L+ Y++ ++ M Sbjct: 180 PEYSILAIDIDDFALMTEDLP-ENKRELIRFSVMNIAEEVLLSRTQGLVCYSQFDHLIGM 238 Query: 230 SYRSTEEAAEAPLILERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHKLF 289 A + E + Q ++ ++ ++ + C++ + S+ EA LK K+ Sbjct: 239 MSGGGLRADFVDHVCEEIQQAVKTYLKLSISIGISRNCTDIAVLSTSYAEAFSALKAKIH 298 Query: 290 SGNTEGQEGSHGLEDSFESGRTMFPRKEKQRLLNAVYACNREQVIGQLEDLQRQYSTAQH 349 G + S E ++P +E++ ++ + N ++ ++ + +++ Q Sbjct: 299 KGKGSLIRYQESMM-STEMQNVLYPSEEEKVIIGCLKTLNSSELHSAIDQIFDRFAAGQT 357 Query: 350 LYPAGYIRKLSAELIMLLSLILYERNESINQLIPG------EPEFVTSIQSQNDPKLVFD 403 P IR + L+++ + E + + +I E E ++ K + D Sbjct: 358 DAPV--IRSICGRLLLMAVSGVEEMSVDVGSIIGTNFNPYREMERFDTLGDLR--KWMND 413 Query: 404 AVKRLYSLLLDLPVQSEMKKNRQTIRTVLDYINNHLDEEIRLEELAQKVFLTPNYLGSLF 463 + RL L+ +++ +K + I+T L Y+ + + + L ++A V++TPNYL +F Sbjct: 414 VLHRLSELVQ----ENKNQKFKGVIKTALRYMEENYNRAVSLADVAAIVYVTPNYLSRIF 469 Query: 464 KESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAGIKPSQ 523 KE +G+ F ++L + R+E AK LL +PG++ Y V++KVGY + YFS++FK +A P + Sbjct: 470 KEEIGVNFVEWLNRYRIEKAKLLLSEPGAKTYAVAEKVGYSDYKYFSQMFKRFADCSPKE 529 Query: 524 YK 525 YK Sbjct: 530 YK 531 >B3KJG1.1 B3KJG1_9BACI Response regulator receiver Length = 539 Score = 184 bits (466), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 143/547 (26%), Positives = 256/547 (46%), Gaps = 49/547 (8%) Query: 6 LLVDDEDFVLDGLKEAIDWKKYGINIAGAVNNGREALEFLEHSGITIDIVFTDIKMPVMD 65 L+VDDE V +G++ I W ++G G NGR+ALE + D+V TDI MP MD Sbjct: 5 LIVDDEPIVREGIRNRIQWSEHGYECIGDCENGRDALEAVTRH--QPDVVLTDINMPYMD 62 Query: 66 GFGLTEALKSAEYPCKIIVLTGHEEFEFAKKAIRYGIFDYLLKPVELESIELTIDRLVKV 125 G L+ + KII+LTG ++FE+A++A++ + D++LKPV + +D+L Sbjct: 63 GLELSRHITERFPKTKIIILTGFDDFEYAQQAVKLQVTDFILKPVTAAELRDMLDKLKLE 122 Query: 126 IRTEKEQSQETAEVEHRLNEGLPLIHERLLFSLLNGTYEPELM----CYIGVPMDAPYYQ 181 + E+ ++ ++ +LNE L L+ ER L L + + M Y +P+ P Y Sbjct: 123 MDEERGHTEHLKRLKKQLNESLVLLRERFLERLASSPMKRSEMESRLDYFDIPLRGPLYI 182 Query: 182 AVIGYTG--------SSNNTWNIEMESVRQSVSAALRSVGNP--VSLAYNERGFILLMSY 231 A+ + N + ++ Q + A G P Y E + ++S Sbjct: 183 AMAADMDELRSDEQHADNELHAFALYNIMQEILA-----GEPGAAVFRYKENKVMTILSG 237 Query: 232 RSTEE-AAEAPLILERVSQELQRKRQIGLNFAQGKPCSEPYQIPQSFQEAREMLKHKLFS 290 ++ A A + E + ++ + + G C E I S + + L+++L Sbjct: 238 SDEKDLHARAQELAEDIRGSTKQFMKFTVTVGIGTICRELQDIRYSCKASEAALEYRLLI 297 Query: 291 GNTE-------GQEGSHGLEDSFESGRTMFPRKEKQRLLNAVYACNREQVIGQLEDLQRQ 343 G + + GS L D E+ + L++A+ A +V + L + Sbjct: 298 GRDQVVHITDLEKRGSGPLLDGIET---------ETALVSAIRAGTGSEVKACIRRLINE 348 Query: 344 YSTAQHLYPAGYIRKLSAELIMLLSLILYERNESINQLIPGEPEFVTSIQSQNDPKLVFD 403 +A Y+R L L +L +L+ E + N+LI E ++ + S D Sbjct: 349 IGSASISIELCYVRVLRVMLAVLQTLM--EIGSNGNELIGKEKRLLSDLYSFRS----LD 402 Query: 404 AVKRLYSLLLDLPVQSEMKKNRQTIRT----VLDYINNHL-DEEIRLEELAQKVFLTPNY 458 ++R + + + ++ K + R+ +D+I H DEE+ ++ + ++F++ +Y Sbjct: 403 EIERWLNEVCEQALRDVAKTRKDIARSQMLEAVDFIQRHYEDEELSIKTVCSRIFMSTSY 462 Query: 459 LGSLFKESVGIGFSDYLMKQRMELAKRLLLQPGSRIYEVSQKVGYKNPHYFSKLFKEYAG 518 +LFK G F +Y+ + RME AK LL + YE++ K GY++P YFS LFK++ G Sbjct: 463 FSALFKSHTGKTFVEYVTEVRMEKAKELLKHSLLKTYEIAAKTGYQDPQYFSVLFKKHTG 522 Query: 519 IKPSQYK 525 P++Y+ Sbjct: 523 DTPTEYR 529 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.136 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 2,983,256,820 Number of extensions: 123021785 Number of successful extensions: 431065 Number of sequences better than 1.0e-05: 8289 Number of HSP's gapped: 440837 Number of HSP's successfully gapped: 8940 Length of query: 525 Length of database: 3,060,696,203 Length adjustment: 140 Effective length of query: 385 Effective length of database: 1,741,754,103 Effective search space: 670575329655 Effective search space used: 670575329655 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)