BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0454.0004.p (585 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region 244 2e-62 B1D4P2.1 B1D4P2_9BACL Multi-sensor signal transduction histidine... 235 8e-60 B0K338.1 B0K338_THEPX Histidine kinase internal region 226 6e-57 B0P6G4.1 B0P6G4_9FIRM Putative uncharacterized protein 223 5e-56 B1D5Z4.1 B1D5Z4_9BACL Integral membrane sensor signal transducti... 218 1e-54 >B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region Length = 598 Score = 244 bits (623), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 172/539 (31%), Positives = 280/539 (51%), Gaps = 28/539 (5%) Query: 56 QVNSLLNQRMTSIKSTALSIVINPEIKEILARGSVADTYEQIRNNESASRILSNAAYSRS 115 QVN+ + +T +K +L+ + NP ++E LA + + S + SR Sbjct: 55 QVNANIQTYITGMKDISLAAMNNPNVREYLASADELEPAQLAVLKAKISDYFHSIRISRK 114 Query: 116 DISEIMI-------VTDRLSIYNYSNPNGFYELSRIEDKPIWAYVDDRKEGFIPPRPNDM 168 DI+ I I ++DR + + N + E+S D+P W +G + + Sbjct: 115 DIASINIFGAGGTFISDR----SNAELNPYIEIS---DQP-WYRQAKENQGQTVISSSHV 166 Query: 169 RN--DGYNPKILTYFHEIAY--GGKSLGYVFINLQFSSFKNLLQGTATGNR--LFYTD-E 221 + G +++ E++ + LG + I+L F ++L GNR +F D E Sbjct: 167 QPVIKGEYRWVVSLSRELSGMDSTQGLGILLIDLNFKVINDMLSKLDLGNRGYVFVIDRE 226 Query: 222 NNEMYNDEGDLLSGSAMDEMLRSFADHLQGYTYTHLDSSKYLSIFTSPN-DFGWRIILFK 280 +Y+ + LL + E L G D + I++ N DFGW+I+ Sbjct: 227 GRIVYHPQQQLLYSNLKTERLDQVLQDKHGSFVVKEDGAS--RIYSIKNTDFGWKIVGVF 284 Query: 281 PYKDVVEGISGLFTRLLLVVLICFILAVIAVIYFSRSITQPLKRLIRQMNKIGHGNFDIQ 340 ++V+ + + L+C ++ V+ + SR++T+P+K+L +M ++ GNFDI+ Sbjct: 285 YENELVDNKKQMQLSFAIAGLLCLVVGVLFSVVLSRNLTRPIKKLQEKMMEVEKGNFDIR 344 Query: 341 LDSDYTNEIGQLNERFRIMSVKIHDLMEESEREQNQLREMELRALQSQINPHFLYNTLDA 400 + ++ EI L F +M +KI +LM + EQ R+ EL ALQ+QINPHFLYNTLD+ Sbjct: 345 VPVGHSREISGLARSFNVMVLKIKELMYQIVVEQEIKRKSELNALQAQINPHFLYNTLDS 404 Query: 401 INWMAIRLKAPEISKMTSNLGKFFRLSLNKGRELTTIAAELEHLNSYIHIMRYKHNNRFE 460 I WMA K E+ MTS L + FR SL+KG+EL IA E+EH+ +Y+ I + ++ ++ Sbjct: 405 IIWMAESKKHDEVILMTSALARLFRASLSKGKELIPIATEVEHITNYLKIQQMRYQDKIT 464 Query: 461 YEEDIAPELLSCETIKIILQPLVENCFVHGLGPSKGEGQIRVTGRMLEDYIQFDVWDSGT 520 + DI L T+K++LQPLVEN HG+ +G G I +TG + I+F V D G Sbjct: 465 FALDIDRGLYPYLTLKVLLQPLVENAIYHGIKNKEGPGTITITGVRRDTRIEFQVKDDGI 524 Query: 521 SVDVAWLNQVL--QQGFESRLGYGIHNVNQRIQLHNGSNYGLTFVEVE-CGTLVQIRLP 576 +D + + +L ++G SR GI NV+QRIQL+ G+ YGL++ V GT V + +P Sbjct: 525 GMDQSKVETLLTSKEGTRSRNSVGIANVHQRIQLYFGTEYGLSYASVPGSGTSVTLVIP 583 >B1D4P2.1 B1D4P2_9BACL Multi-sensor signal transduction histidine kinase Length = 596 Score = 235 bits (600), Expect = 8e-60, Method: Compositional matrix adjust. Identities = 164/545 (30%), Positives = 286/545 (52%), Gaps = 39/545 (7%) Query: 56 QVNSLLNQRMTSIKSTALSIVINPEIKEILAR-GSVADTYEQIRNNESASRILSNAAYSR 114 QVN+ + +TS+++ ++ + N +++E+++ G+ A E++ + S + SR Sbjct: 54 QVNANIQTYITSMENISMLALSNEDVRELVSEEGNNATNSEELAREQRISAYFHSIIASR 113 Query: 115 SDISEI-------MIVTDRLSIYNYSNPNGFYELSRIEDKPIWAYVDDRKEGFI---PPR 164 DI+ I + V+DR + NP+ R+ ++P W G I Sbjct: 114 KDIASINVIGYNGLFVSDREHVE--LNPS-----VRLAEQP-WYTSAQEASGRIVVSSSH 165 Query: 165 PNDMRNDGYNPKILTYFHEIAYGGKS--LGYVFINLQFSSFKNLLQGTATGNR--LFYTD 220 M D Y+ +++ E+ ++ G + ++L FS + L R +F D Sbjct: 166 VQHMFKDEYDW-VVSLSRELWSKDQTEPRGVLLVDLNFSVINDTLNNIDLSKRGYIFIVD 224 Query: 221 EN-NEMYNDEGDL----LSGSAMDEMLRSFADHLQGYTYTHLDSSKYLSIFT-SPNDFGW 274 E+ N +Y+ + L L +DE+L +G D K I+T FGW Sbjct: 225 EDGNIVYHPQQQLIYSNLKSEKIDEVL------AKGSGSFMTDEGKTSRIYTIQDTGFGW 278 Query: 275 RIILFKPYKDVVEGISGLFTRLLLVVLICFILAVIAVIYFSRSITQPLKRLIRQMNKIGH 334 +I+ +++ + ++ + C I+ ++ ++ SR++++P+K+L M K+ Sbjct: 279 KIVGVSYVNELIGNKREMQLSMVAAGIFCLIVGLLLAVFISRNLSRPIKQLQEHMKKVEK 338 Query: 335 GNFDIQLDSDYTNEIGQLNERFRIMSVKIHDLMEESEREQNQLREMELRALQSQINPHFL 394 G F+I++ EI L F +M VKI +LM + REQ R+ EL ALQ+QINPHFL Sbjct: 339 GIFNIRVPIGNPREIASLARTFNLMVVKIEELMSQVVREQEIKRKSELTALQAQINPHFL 398 Query: 395 YNTLDAINWMAIRLKAPEISKMTSNLGKFFRLSLNKGRELTTIAAELEHLNSYIHIMRYK 454 YNTLD+I WMA K E+ MTS L + FR S+++G+EL +I E+EH+ +Y+ I + + Sbjct: 399 YNTLDSIIWMAEGKKTDEVVLMTSALARLFRSSISRGQELVSIRTEIEHVANYLTIQKIR 458 Query: 455 HNNRFEYEEDIAPELLSCETIKIILQPLVENCFVHGLGPSKGEGQIRVTGRMLEDYIQFD 514 + ++ ++ D+ P++ + T+K++LQPL+EN HG+ G G I+VTG + YI + Sbjct: 459 YKDKLDFHIDVDPDIYAYRTLKVLLQPLLENAIYHGIKNRIGTGTIQVTGGKRDGYIWLE 518 Query: 515 VWDSGTSVDVAWLNQVLQQGFESR--LGYGIHNVNQRIQLHNGSNYGLTFVEVEC-GTLV 571 V D+G ++ L +L+ R G G+ NV++RIQL+ G +YGLT+ V+ GT V Sbjct: 519 VSDNGVGMEAEALRTILEPRRSDRESKGVGVVNVHERIQLYFGKDYGLTYKSVQDEGTTV 578 Query: 572 QIRLP 576 +R+ Sbjct: 579 TVRIA 583 >B0K338.1 B0K338_THEPX Histidine kinase internal region Length = 567 Score = 226 bits (575), Expect = 6e-57, Method: Compositional matrix adjust. Identities = 116/326 (35%), Positives = 203/326 (62%) Query: 251 GYTYTHLDSSKYLSIFTSPNDFGWRIILFKPYKDVVEGISGLFTRLLLVVLICFILAVIA 310 G + ++ +K + I+ + GW+++ ++ E + + L L+ ++A + Sbjct: 239 GSDFITINGNKIMVIYNTLPQNGWKLVGMVSMAELNEKAEMIRNFIYLTALLSLVIAALI 298 Query: 311 VIYFSRSITQPLKRLIRQMNKIGHGNFDIQLDSDYTNEIGQLNERFRIMSVKIHDLMEES 370 +YFS SI+QP+ +L +M K+ GNF+I ++ ++ EIG L F M +I++L+ E Sbjct: 299 SLYFSYSISQPIIKLATEMKKVEKGNFNISVEENWDGEIGVLYSSFNYMIERINELIHEV 358 Query: 371 EREQNQLREMELRALQSQINPHFLYNTLDAINWMAIRLKAPEISKMTSNLGKFFRLSLNK 430 + + ++ EL+ALQ+QINPHFLYNTLD +NW+A++ PEISK+ ++L R S+NK Sbjct: 359 YLSKIKEKDAELKALQAQINPHFLYNTLDTVNWLAVKHNVPEISKIVNSLASILRYSINK 418 Query: 431 GRELTTIAAELEHLNSYIHIMRYKHNNRFEYEEDIAPELLSCETIKIILQPLVENCFVHG 490 G ++TT+ EL+H+ SYI I + + ++FE +I +L +TIK+ILQPLVEN +HG Sbjct: 419 GNDVTTVENELKHVESYITIQKIRFKDKFEVSFNIDKRVLHYKTIKLILQPLVENAIIHG 478 Query: 491 LGPSKGEGQIRVTGRMLEDYIQFDVWDSGTSVDVAWLNQVLQQGFESRLGYGIHNVNQRI 550 + +G+G+I + G + + I F+V ++G +D+ +N++L + + YGI NVN+RI Sbjct: 479 IETYEGKGKILINGYLDGEKIVFEVINNGNPIDLDLVNKLLDSPADDKDSYGIQNVNERI 538 Query: 551 QLHNGSNYGLTFVEVECGTLVQIRLP 576 +L+ G YGL + ++ T+ +I +P Sbjct: 539 KLYYGEEYGLYYQAIDSNTVARIVIP 564 >B0P6G4.1 B0P6G4_9FIRM Putative uncharacterized protein Length = 603 Score = 223 bits (568), Expect = 5e-56, Method: Compositional matrix adjust. Identities = 126/399 (31%), Positives = 209/399 (52%), Gaps = 11/399 (2%) Query: 187 GGKSLGYVFINLQFSSFKNLLQGTATGNR--LFYTDENNEM-YNDEGDLLSGSAMDEMLR 243 G + G + +++ +S + L + G ++ D E+ Y+ LL + + E R Sbjct: 192 GAVTRGVLLVDMNYSGIEQLFKNVNLGGSGYVYLVDSAGEIIYHPRQQLLYSNLLSENNR 251 Query: 244 SFADHLQGYTYTHLDSSKYLSIFTSPNDFGWRIILFKPYKDVVEGISGLFTRLLLVVLIC 303 + + G D + + + GW+I+ P +D V + T + ++L Sbjct: 252 AAVSYDDGSHVETFDGQERIVTIKTVGYTGWKIVGVTPMQDAVSDSYAIRTFAVFIILFT 311 Query: 304 FILAVIAVIYFSRSITQPLKRLIRQMNKIGHGNFDIQLDSDYTNEIGQLNERFRIMSVKI 363 L + ++ S I P+KRL R + + GN+D ++ + E+ L + R M ++ Sbjct: 312 IFLMIFVNLFISSRIANPIKRLERSVKGLEGGNWDTEIAVGGSYEVAHLGKTIRTMVAQM 371 Query: 364 HDLMEESEREQNQLREMELRALQSQINPHFLYNTLDAINWMAIRLKAPEISKMTSNLGKF 423 LM++ EQ R+ E ALQSQINPHFLYNTLD+I WM + PE M + L + Sbjct: 372 RSLMDDIVAEQESKRKSEFDALQSQINPHFLYNTLDSIVWMIENERYPEAVTMVTALARL 431 Query: 424 FRLSLNKGRELTTIAAELEHLNSYIHIMRYKHNNRFEYEEDIAPELLSCETIKIILQPLV 483 FR+SL+KG+ + +++ ELEH +Y+ I ++ N+F D PE L TIK+I+QPL+ Sbjct: 432 FRISLSKGKTIISVSDELEHARNYLTIQTMRYKNKFTVSVDAQPETLGLSTIKLIIQPLL 491 Query: 484 ENCFVHGLGPSKGEGQIRVTGRMLEDYIQFDVWDSGTSVDVAWLNQVLQQGFESRL---- 539 EN HG+ + G+G+I V + +D + DV D+G + +L E+R+ Sbjct: 492 ENAIYHGMEFADGDGEICVRAYLADDDLIIDVEDNGCGIPADVCATLLTD--ETRVRSKG 549 Query: 540 -GYGIHNVNQRIQLHNGSNYGLTFV-EVECGTLVQIRLP 576 G G+ NV+QRI+L+ G YGLT + E + GT +++RLP Sbjct: 550 SGIGLRNVHQRIRLYYGEPYGLTIISEPDVGTTIRVRLP 588 >B1D5Z4.1 B1D5Z4_9BACL Integral membrane sensor signal transduction histidine kinase Length = 578 Score = 218 bits (556), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 131/374 (35%), Positives = 198/374 (52%), Gaps = 6/374 (1%) Query: 206 LLQGTATGNRLFYTDENNEMYNDEGDLLSGSAMDEMLRSFADHLQGYTY--THLDSSKYL 263 LL G++ F DEN + + G+ MD + Q +Y L+ + Y+ Sbjct: 205 LLSGSS---EFFIIDENKRIISSLDQSKIGTTMDSKYDDHRLYQQNSSYFKASLNGNPYI 261 Query: 264 SIFTSPNDFGWRIILFKPYKDVVEGISGLFTRLLLVVLICFILAVIAVIYFSRSITQPLK 323 + + + GW+++ P ++ + + VL FIL + +I FS + PL Sbjct: 262 ETYYNLSRPGWKLVNLVPMNELSSDTKLIRNVTIYAVLGSFILCSLMIILFSLKVLSPLN 321 Query: 324 RLIRQMNKIGHGNFDIQLDSDYTNEIGQLNERFRIMSVKIHDLMEESEREQNQLREMELR 383 R+ R M I NF++ + +EI ++ F MS ++ +L+ E Q + +E EL+ Sbjct: 322 RIRRSMRAIEDENFNVNIPVKGNDEIALISRSFNRMSRRLDELINEVYAGQIKQKEAELK 381 Query: 384 ALQSQINPHFLYNTLDAINWMAIRLKAPEISKMTSNLGKFFRLSLNKGRELTTIAAELEH 443 ALQ+QINPHFLYNTLD I WMA KA E SK+ L K FRL+LN G E TT+A+E+EH Sbjct: 382 ALQAQINPHFLYNTLDTIYWMARMEKAYESSKLVQALSKLFRLALNSGNEQTTVASEVEH 441 Query: 444 LNSYIHIMRYKHNNRFEYEEDIAPELLSCETIKIILQPLVENCFVHGLGPSKGEGQIRVT 503 L SYI I + + ++ D+ E L+C T+K++LQPLVEN HG+ G +R+T Sbjct: 442 LRSYILIQEKRFEDCILFDIDVELETLACRTVKLVLQPLVENAIHHGIEKKGKSGTVRIT 501 Query: 504 GRMLEDYIQFDVWDSGTSVDVAWLNQVLQQGFESRLGYGIHNVNQRIQLHNGSNYGLTF- 562 + + + + + D G V+ A + +LQQ + G+GI NVN RIQL G +GL F Sbjct: 502 IKREDKELVYRITDDGVGVEEADITSLLQQVKDDNRGFGIKNVNDRIQLICGQEFGLAFH 561 Query: 563 VEVECGTLVQIRLP 576 G V +R P Sbjct: 562 TSPGNGMTVIVRQP 575 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.320 0.137 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,221,029,108 Number of extensions: 134319170 Number of successful extensions: 354866 Number of sequences better than 1.0e-05: 2312 Number of HSP's gapped: 352973 Number of HSP's successfully gapped: 2312 Length of query: 585 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 444 Effective length of database: 1,732,333,088 Effective search space: 769155891072 Effective search space used: 769155891072 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 134 (56.2 bits)