BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0450.0025.p (582 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KIN1.1 B3KIN1_9BACI ABC transporter related 842 0.0 O07550.1 YHEI_BACSU Probable multidrug resistance ABC transporte... 706 0.0 Q65LV9.1 Q65LV9_BACLD YheI 697 0.0 A7GLM3.1 A7GLM3_BACCN ABC transporter-related protein 697 0.0 A8FBI5.1 A8FBI5_BACP2 ABC superfamily ATP binding cassette trans... 696 0.0 >B3KIN1.1 B3KIN1_9BACI ABC transporter related Length = 585 Score = 842 bits (2175), Expect = 0.0, Method: Compositional matrix adjust. Identities = 404/582 (69%), Positives = 484/582 (83%) Query: 1 LFSVLRNLGWFFRREKKRYXXXXXXXXXXXXXXXXPPRLLGNAIDDIVNGSITAGSLMKY 60 +F+VL+NLGWFF+REKKRY PP LLGNAIDDIV+ SIT SL++Y Sbjct: 1 MFAVLKNLGWFFKREKKRYLIGLALLIFCGLVELLPPLLLGNAIDDIVSSSITWASLVQY 60 Query: 61 IGLIVLMLLIIYWITYIWMHKLFGGSNLVERLLRSRFMNHLMTMTPSFFERNRTGDLMAR 120 + +I+ ++ ++Y TYIWMH+LFGG+NLVERLLR+R+MNHL+ M P FFERNRTGDLMA+ Sbjct: 61 LLMILGIVAVVYCATYIWMHRLFGGANLVERLLRTRYMNHLLRMLPPFFERNRTGDLMAK 120 Query: 121 ATNDIRAVSATVGFGMLTLVDSTIFLTVVLLAMGFLVSWKLTXXXXXXXXXXXXXMIFYG 180 ATND+R+V+AT GFGML + DSTI+L VVL AMGF+VSWKLT M+ YG Sbjct: 121 ATNDLRSVAATAGFGMLVMTDSTIYLIVVLFAMGFIVSWKLTLAAILPMPIIAIGMVIYG 180 Query: 181 KAIHDRYSLAQDAFGDMNDQVLESVSGIRVIRAYVQERLDEKRFGEITEDVYRKNMAVAK 240 +AIH RY+LAQDAFGDMNDQVLESV+G+RVIRAYVQER D++RF +IT+DVYRKN+AVAK Sbjct: 181 RAIHKRYTLAQDAFGDMNDQVLESVAGVRVIRAYVQERADQQRFQDITDDVYRKNLAVAK 240 Query: 241 VDSFFEPTIRLCVGLSYVIALTFGIYLVFRNQITLGDLVSFNMYLGMIVWPMFAIGELIN 300 VD+ FEPTI +GLSYVI L +G+YLVF+NQITLGDLVSFNMYLGM++WPMFAIGELIN Sbjct: 241 VDALFEPTINFSIGLSYVIGLAYGVYLVFQNQITLGDLVSFNMYLGMMIWPMFAIGELIN 300 Query: 301 IMQRGGASLERIDETLNSKPDVQDAALPVPVAQPTSIELKDVTFRYPTSTIDNLTGVSFT 360 IMQRG ASL+R++ETL + PDV D A PV V P +I+ KDVTFRYPTSTI+NL +SFT Sbjct: 301 IMQRGNASLDRVNETLKTPPDVADVADPVDVKVPDTIQFKDVTFRYPTSTIENLQNISFT 360 Query: 361 LTQGQTLGVVGRTGSGKSTLLKQLLHEYPTGRGEILISDVPIDKIALDQLHSWMGYVPQE 420 L +GQTLGVVGRTGSGKSTLLKQLLHEYPTG G+ILIS VP++++A DQLHSW+GYVPQE Sbjct: 361 LQKGQTLGVVGRTGSGKSTLLKQLLHEYPTGTGDILISGVPMERLATDQLHSWIGYVPQE 420 Query: 421 QILFSKSVRENIQFGHHGASDERIMSAITAAAFQNXXXXXXXXXXXXVGERGVSLSGGQK 480 QILFSK+VR+NIQFG ASDE IM AIT AAF VGE+GV+LSGGQK Sbjct: 421 QILFSKTVRQNIQFGKKDASDELIMEAITTAAFDRDLVTLSDGLDTIVGEKGVALSGGQK 480 Query: 481 QRVSISRAFIANPDILILDDALSAVDARTEARIIENIRDERAGKTTLISTHRLSAIEHAD 540 QRVS++RAFI +P+ILILDD+LSAVDARTEARII+NIR +RAGKTTLISTHRLSA++HAD Sbjct: 481 QRVSLARAFIGDPEILILDDSLSAVDARTEARIIDNIRSKRAGKTTLISTHRLSAVQHAD 540 Query: 541 LIVVLDNGKIIERGTHQELLDMNGWYREQFDRQQVENNLTND 582 LIVVL++G+I E+GTH ELL++ GWYREQF+RQQVENNLT++ Sbjct: 541 LIVVLEDGRITEQGTHDELLELGGWYREQFERQQVENNLTSE 582 >O07550.1 YHEI_BACSU Probable multidrug resistance ABC transporter ATP-binding/permease protein yheI EC=3.6.3.- Length = 585 Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 328/575 (57%), Positives = 431/575 (74%) Query: 1 LFSVLRNLGWFFRREKKRYXXXXXXXXXXXXXXXXPPRLLGNAIDDIVNGSITAGSLMKY 60 +FSVL+ LGWFF+ RY PP+LLGNAIDD+ G+ TA L+ Y Sbjct: 1 MFSVLKKLGWFFKAYWLRYTIAIVLLLAVNVIEMFPPKLLGNAIDDMKAGAFTAEGLLFY 60 Query: 61 IGLIVLMLLIIYWITYIWMHKLFGGSNLVERLLRSRFMNHLMTMTPSFFERNRTGDLMAR 120 IG+ ++ +Y ++Y WMH+LFGG+NL+E++LR++ M HL+TM+P F+E+NRTGDLMAR Sbjct: 61 IGIFFVLTAAVYIMSYFWMHQLFGGANLMEKILRTKLMGHLLTMSPPFYEKNRTGDLMAR 120 Query: 121 ATNDIRAVSATVGFGMLTLVDSTIFLTVVLLAMGFLVSWKLTXXXXXXXXXXXXXMIFYG 180 TND++AVS T GFG+LTLVDST+F+ + L MGFL+SWKLT + YG Sbjct: 121 GTNDLQAVSLTTGFGILTLVDSTMFMMTIFLTMGFLISWKLTFAAIIPLPVMAIAISLYG 180 Query: 181 KAIHDRYSLAQDAFGDMNDQVLESVSGIRVIRAYVQERLDEKRFGEITEDVYRKNMAVAK 240 IH+R++ AQ+AFG +ND+VLESVSG+RVIRAYVQE D +RF E+T DVY+KNM VA Sbjct: 181 SKIHERFTEAQNAFGALNDRVLESVSGVRVIRAYVQETNDVRRFNEMTADVYQKNMKVAF 240 Query: 241 VDSFFEPTIRLCVGLSYVIALTFGIYLVFRNQITLGDLVSFNMYLGMIVWPMFAIGELIN 300 +DS FEPT++L VG SY+I L +G +LVFRN++TLG+LVSFN+YLGM++WPMFAIGELIN Sbjct: 241 IDSLFEPTVKLLVGASYLIGLGYGAFLVFRNELTLGELVSFNVYLGMMIWPMFAIGELIN 300 Query: 301 IMQRGGASLERIDETLNSKPDVQDAALPVPVAQPTSIELKDVTFRYPTSTIDNLTGVSFT 360 +MQRG ASL+R++ETL+ + DV D P + +P I V+F YP+ST DNL +SFT Sbjct: 301 VMQRGNASLDRVNETLSYETDVTDPKQPADLKEPGDIVFSHVSFTYPSSTSDNLQDISFT 360 Query: 361 LTQGQTLGVVGRTGSGKSTLLKQLLHEYPTGRGEILISDVPIDKIALDQLHSWMGYVPQE 420 + +GQT+G+ G+TGSGK+T++KQLL +YP G G I S VPI +I LD+L W+GYVPQ+ Sbjct: 361 VRKGQTVGIAGKTGSGKTTIIKQLLRQYPPGEGSITFSGVPIQQIPLDRLRGWIGYVPQD 420 Query: 421 QILFSKSVRENIQFGHHGASDERIMSAITAAAFQNXXXXXXXXXXXXVGERGVSLSGGQK 480 +LFS++V+ENI +G A+D+ + AI A F+ VGE+GV+LSGGQK Sbjct: 421 HLLFSRTVKENILYGKQDATDKEVQQAIAEAHFEKDLHMLPSGLETMVGEKGVALSGGQK 480 Query: 481 QRVSISRAFIANPDILILDDALSAVDARTEARIIENIRDERAGKTTLISTHRLSAIEHAD 540 QR+SI+RA +ANP+ILILDD+LSAVDA+TEA II+NIR+ R GKTT I THRLSA+EHAD Sbjct: 481 QRISIARALMANPEILILDDSLSAVDAKTEAAIIKNIRENRKGKTTFILTHRLSAVEHAD 540 Query: 541 LIVVLDNGKIIERGTHQELLDMNGWYREQFDRQQV 575 LI+V+D G I ERGTHQELL NGWYREQ++RQQ+ Sbjct: 541 LILVMDGGVIAERGTHQELLANNGWYREQYERQQL 575 >Q65LV9.1 Q65LV9_BACLD YheI Length = 584 Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 329/578 (56%), Positives = 437/578 (75%), Gaps = 1/578 (0%) Query: 1 LFSVLRNLGWFFRREKKRYXXXXXXXXXXXXXXXXPPRLLGNAIDDIVNGSITAGSLMKY 60 +FSVL LGWFF+ +RY PP+LLGNAIDD+ G+ + ++ Y Sbjct: 1 MFSVLWKLGWFFKASWRRYTIAVVLLIIVNVLEMFPPKLLGNAIDDMQAGTFSKAGMLGY 60 Query: 61 IGLIVLMLLIIYWITYIWMHKLFGGSNLVERLLRSRFMNHLMTMTPSFFERNRTGDLMAR 120 IGL + + ++Y ++Y WM++LFGG+NLVE++LRS+ M HL+ MTPSF+E+NRTGDLMAR Sbjct: 61 IGLFLALGAVVYTLSYYWMYQLFGGANLVEKILRSKLMGHLLKMTPSFYEKNRTGDLMAR 120 Query: 121 ATNDIRAVSATVGFGMLTLVDSTIFLTVVLLAMGFLVSWKLTXXXXXXXXXXXXXMIFYG 180 ATND++A+S T GFG+LTLVDST+++ +LL MGFL+SWKLT + YG Sbjct: 121 ATNDLKAISMTAGFGILTLVDSTMYMLTILLTMGFLISWKLTLASIIPLPLMAAAISIYG 180 Query: 181 KAIHDRYSLAQDAFGDMNDQVLESVSGIRVIRAYVQERLDEKRFGEITEDVYRKNMAVAK 240 K IH+R++ AQDAFG +NDQVLESVSG+RVIRAYVQE+ D RF +T DVY+KNM VA Sbjct: 181 KKIHERFTEAQDAFGALNDQVLESVSGVRVIRAYVQEKNDVSRFNSMTADVYKKNMKVAL 240 Query: 241 VDSFFEPTIRLCVGLSYVIALTFGIYLVFRNQITLGDLVSFNMYLGMIVWPMFAIGELIN 300 +DS FEPT++L VG+SY+I L +G YLVFR+Q+TLG+LVSFN+YLGM++WPMFAIGELIN Sbjct: 241 IDSLFEPTVKLLVGISYLIGLGYGAYLVFRSQLTLGELVSFNVYLGMLIWPMFAIGELIN 300 Query: 301 IMQRGGASLERIDETLNSKPDVQDAALPVPVAQPTSIELKDVTFRYPTSTIDNLTGVSFT 360 +MQRG ASL+R++ETL +PDV++ A A+P I VTF YP+S +NL +SFT Sbjct: 301 VMQRGNASLDRVNETLAYEPDVREPAE-PEAAEPGDIVFDGVTFTYPSSASENLADISFT 359 Query: 361 LTQGQTLGVVGRTGSGKSTLLKQLLHEYPTGRGEILISDVPIDKIALDQLHSWMGYVPQE 420 + +GQT+G+VG+TGSGK+TL+KQLL +YP G+G I IS VPI+++ LDQL SW+GYVPQ+ Sbjct: 360 VLEGQTVGIVGKTGSGKTTLVKQLLRQYPQGKGTITISGVPIERLPLDQLRSWIGYVPQD 419 Query: 421 QILFSKSVRENIQFGHHGASDERIMSAITAAAFQNXXXXXXXXXXXXVGERGVSLSGGQK 480 +LFSKSV++NI FG H A + + + I+AA + VGE+GV+LSGGQK Sbjct: 420 HVLFSKSVKDNILFGGHLAEERDLHAVISAAHLKKDIEMLSDGLETMVGEKGVALSGGQK 479 Query: 481 QRVSISRAFIANPDILILDDALSAVDARTEARIIENIRDERAGKTTLISTHRLSAIEHAD 540 QR+SI+RA IA P ILILDD+LSAVDA+TEA IIENIR R GKTT I++HR+SA+EHAD Sbjct: 480 QRISIARAMIAEPHILILDDSLSAVDAKTEAAIIENIRSRRKGKTTFITSHRMSAVEHAD 539 Query: 541 LIVVLDNGKIIERGTHQELLDMNGWYREQFDRQQVENN 578 I+V+++G+I+ERGTHQEL+ GWY EQ++ QQ+ + Sbjct: 540 FILVMEDGRIVERGTHQELIGRKGWYFEQYEAQQLPSG 577 >A7GLM3.1 A7GLM3_BACCN ABC transporter-related protein Length = 584 Score = 697 bits (1800), Expect = 0.0, Method: Compositional matrix adjust. Identities = 321/576 (55%), Positives = 439/576 (76%) Query: 1 LFSVLRNLGWFFRREKKRYXXXXXXXXXXXXXXXXPPRLLGNAIDDIVNGSITAGSLMKY 60 +FSVL+ L WFF+ KRY PP++LG ID I GS+T G+++ Y Sbjct: 1 MFSVLQKLRWFFKEHWKRYSIAIGALLIVNIVEIIPPKVLGLTIDQIKTGSLTNGTILAY 60 Query: 61 IGLIVLMLLIIYWITYIWMHKLFGGSNLVERLLRSRFMNHLMTMTPSFFERNRTGDLMAR 120 I ++ + + Y +T+IW H+LFGG+ ++E+ +RS+FM HL+ MTP+F+++NRTGDLMAR Sbjct: 61 IWVLFGVTIGGYVLTFIWQHQLFGGAFVLEKTMRSKFMGHLLKMTPTFYQKNRTGDLMAR 120 Query: 121 ATNDIRAVSATVGFGMLTLVDSTIFLTVVLLAMGFLVSWKLTXXXXXXXXXXXXXMIFYG 180 ATND++A+S T GFG+LTLVDS++++ ++ MGF +SW+LT M YG Sbjct: 121 ATNDLKAISITAGFGILTLVDSSLYMLTIVFMMGFSISWQLTFAALIPLPIMAYAMNVYG 180 Query: 181 KAIHDRYSLAQDAFGDMNDQVLESVSGIRVIRAYVQERLDEKRFGEITEDVYRKNMAVAK 240 K +H+R+++AQDAFGDMND+VLES++G+RVIRAYVQER D++RF + +DVY KNM VA+ Sbjct: 181 KKLHERFTIAQDAFGDMNDKVLESIAGVRVIRAYVQERADQERFQHLGDDVYEKNMKVAR 240 Query: 241 VDSFFEPTIRLCVGLSYVIALTFGIYLVFRNQITLGDLVSFNMYLGMIVWPMFAIGELIN 300 +D+ F+PT+++ VGLSY+I L +G YLVF+ ITLG+LVSFN+YLGM++WPMFAIGELIN Sbjct: 241 IDALFQPTVKMLVGLSYLIGLVYGAYLVFQTTITLGELVSFNVYLGMMIWPMFAIGELIN 300 Query: 301 IMQRGGASLERIDETLNSKPDVQDAALPVPVAQPTSIELKDVTFRYPTSTIDNLTGVSFT 360 +MQRG ASL+R++ETL +PDV++ P + QP I+ V+F YP+S NL VSF+ Sbjct: 301 VMQRGNASLDRVNETLAYEPDVKNPQNPQMIQQPKQIQFDHVSFSYPSSAKVNLKQVSFS 360 Query: 361 LTQGQTLGVVGRTGSGKSTLLKQLLHEYPTGRGEILISDVPIDKIALDQLHSWMGYVPQE 420 L QG+TLG+VG+TGSGK+T+++QLL EYP G G I IS+VP+++I ++++ SW+GYVPQE Sbjct: 361 LKQGETLGIVGKTGSGKTTIVRQLLREYPLGEGNITISNVPLNRIPIEKVRSWIGYVPQE 420 Query: 421 QILFSKSVRENIQFGHHGASDERIMSAITAAAFQNXXXXXXXXXXXXVGERGVSLSGGQK 480 ILFSK+ RENI FG+ AS+E + AI AAF+ VGE+GVSLSGGQK Sbjct: 421 HILFSKTARENILFGNREASEEDLWKAIEIAAFKKDLEFLPEGLETLVGEKGVSLSGGQK 480 Query: 481 QRVSISRAFIANPDILILDDALSAVDARTEARIIENIRDERAGKTTLISTHRLSAIEHAD 540 QR+SI+RA I NP+ILILDD+LSAVDARTEA IIENIR ER+GKTT+I+THRLSA++HAD Sbjct: 481 QRISIARAVIQNPEILILDDSLSAVDARTEAAIIENIRTERSGKTTIITTHRLSAVQHAD 540 Query: 541 LIVVLDNGKIIERGTHQELLDMNGWYREQFDRQQVE 576 I+V+DNG++IE GTH++L+ GWYR+QF+RQQ E Sbjct: 541 WILVMDNGEVIEEGTHEQLVQNGGWYRKQFERQQGE 576 >A8FBI5.1 A8FBI5_BACP2 ABC superfamily ATP binding cassette transporter, membrane protein Length = 585 Score = 696 bits (1795), Expect = 0.0, Method: Compositional matrix adjust. Identities = 315/579 (54%), Positives = 435/579 (75%) Query: 1 LFSVLRNLGWFFRREKKRYXXXXXXXXXXXXXXXXPPRLLGNAIDDIVNGSITAGSLMKY 60 +FSV LGWFF++E +RY PPR LG A+DDI +G T S+M Y Sbjct: 1 MFSVFTKLGWFFKQEWRRYTIAITLLLIVNVLEMLPPRYLGQAVDDIRSGQFTTSSMMFY 60 Query: 61 IGLIVLMLLIIYWITYIWMHKLFGGSNLVERLLRSRFMNHLMTMTPSFFERNRTGDLMAR 120 + + L+ +++Y +TY WM++LFGG+N++ER++R + M HL+ MTP+F+E+ +TG+LMA Sbjct: 61 VAIFCLLGVVVYTLTYFWMYQLFGGANVMERVMRGKLMRHLLKMTPTFYEKKKTGNLMAL 120 Query: 121 ATNDIRAVSATVGFGMLTLVDSTIFLTVVLLAMGFLVSWKLTXXXXXXXXXXXXXMIFYG 180 TND+ AV+ T GFG+LTLVDST ++ ++ MG +SWKLT + +YG Sbjct: 121 GTNDLNAVALTTGFGVLTLVDSTAYMLMIFFTMGLTISWKLTLMAIIPMPLMALLIAYYG 180 Query: 181 KAIHDRYSLAQDAFGDMNDQVLESVSGIRVIRAYVQERLDEKRFGEITEDVYRKNMAVAK 240 IHDR+++AQDAFGDMND+VLESV+G+RVIR++VQE+ D +RF E+T+DV++KNM VA Sbjct: 181 SKIHDRFTVAQDAFGDMNDRVLESVAGVRVIRSFVQEKQDVERFREMTDDVFQKNMRVAV 240 Query: 241 VDSFFEPTIRLCVGLSYVIALTFGIYLVFRNQITLGDLVSFNMYLGMIVWPMFAIGELIN 300 +DS FEPT++L VG+SY+I + +G YLVF++ +T+G+LV+FN+YLGM++WPMFAIGELIN Sbjct: 241 IDSLFEPTVKLLVGVSYLIGIGYGAYLVFQSDLTIGELVAFNVYLGMMIWPMFAIGELIN 300 Query: 301 IMQRGGASLERIDETLNSKPDVQDAALPVPVAQPTSIELKDVTFRYPTSTIDNLTGVSFT 360 IMQRG ASL+R++ TL+ KPDV +A+ P + +P I+ VTFRYPTS +NL VSFT Sbjct: 301 IMQRGNASLDRLNHTLSYKPDVTNASQPKTLQEPGDIQFDHVTFRYPTSPKNNLIDVSFT 360 Query: 361 LTQGQTLGVVGRTGSGKSTLLKQLLHEYPTGRGEILISDVPIDKIALDQLHSWMGYVPQE 420 + +GQT+G+ G+TGSGK+T++KQLL +YPTG G+IL+S VPI +I LDQL W+GYVPQ+ Sbjct: 361 VRKGQTIGITGKTGSGKTTIVKQLLRQYPTGDGQILLSGVPIQEIELDQLFQWIGYVPQD 420 Query: 421 QILFSKSVRENIQFGHHGASDERIMSAITAAAFQNXXXXXXXXXXXXVGERGVSLSGGQK 480 ILFSKSV EN++FGH A + AI A F+ VGE+GV+LSGGQK Sbjct: 421 HILFSKSVEENMRFGHRDAKQNELAQAIKDAYFEKDLRLLPEGLETMVGEKGVALSGGQK 480 Query: 481 QRVSISRAFIANPDILILDDALSAVDARTEARIIENIRDERAGKTTLISTHRLSAIEHAD 540 QR+SI+RA + +PDILILDD+LSAVDA+TE I+EN+R R GKTT I+THRLSA+EHAD Sbjct: 481 QRISIARALLIDPDILILDDSLSAVDAKTETAILENLRQNRHGKTTFITTHRLSAVEHAD 540 Query: 541 LIVVLDNGKIIERGTHQELLDMNGWYREQFDRQQVENNL 579 LI+V++ G+I+++GTH+EL+ +GWY+EQF RQQ+ N L Sbjct: 541 LILVMEEGRIVQKGTHKELIQQDGWYKEQFLRQQLTNQL 579 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.323 0.139 0.403 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,056,846,411 Number of extensions: 120049298 Number of successful extensions: 711054 Number of sequences better than 1.0e-05: 61690 Number of HSP's gapped: 655969 Number of HSP's successfully gapped: 65761 Length of query: 582 Length of database: 3,060,696,203 Length adjustment: 141 Effective length of query: 441 Effective length of database: 1,732,333,088 Effective search space: 763958891808 Effective search space used: 763958891808 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.5 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (22.0 bits) S2: 134 (56.2 bits)