BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0444.0015.p (601 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region 173 5e-41 B0P6G4.1 B0P6G4_9FIRM Putative uncharacterized protein 171 2e-40 B1D7N6.1 B1D7N6_9BACL Integral membrane sensor signal transducti... 169 6e-40 B1DBG2.1 B1DBG2_9BACL Histidine kinase internal region 169 8e-40 B3K5A3.1 B3K5A3_9BACI Histidine kinase internal region 169 9e-40 >B3KJG0.1 B3KJG0_9BACI Histidine kinase internal region Length = 598 Score = 173 bits (438), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 112/400 (28%), Positives = 206/400 (51%), Gaps = 16/400 (4%) Query: 194 GVLLISMSNDQYQRQIENIQLGNRGSISLLTDDGMTIATTSR--LEPKEDTGRVQNILKH 251 G+LLI ++ + + LGNRG + ++ +G + + L T R+ +L+ Sbjct: 194 GILLIDLNFKVINDMLSKLDLGNRGYVFVIDREGRIVYHPQQQLLYSNLKTERLDQVLQ- 252 Query: 252 WKELDRPNQFAV----GSSIVSVKQTSTYDNWIVVSEIPSKELTASAEIIRRTVAYFLGI 307 D+ F V S I S+K T W +V EL + + ++ + A + Sbjct: 253 ----DKHGSFVVKEDGASRIYSIKNTDF--GWKIVGVFYENELVDNKKQMQLSFAIAGLL 306 Query: 308 LVFLGALCVVGFGYQLYRPLQAVKRQVDAIKKGHFDARVTHFANNEIGDLGRMLNTMAVR 367 + +G L V L RP++ ++ ++ ++KG+FD RV + EI L R N M ++ Sbjct: 307 CLVVGVLFSVVLSRNLTRPIKKLQEKMMEVEKGNFDIRVPVGHSREISGLARSFNVMVLK 366 Query: 368 IQDLLADLHDSEELKHKLEIRALQSQINPHFMYNTLNTIRMFAMMKDYEKINTLMGRLVA 427 I++L+ + +E+K K E+ ALQ+QINPHF+YNTL++I A K ++++ + L Sbjct: 367 IKELMYQIVVEQEIKRKSELNALQAQINPHFLYNTLDSIIWMAESKKHDEVILMTSALAR 426 Query: 428 LLRYSMENYEQTVQLQQELDYLADYVGLLNMRYKCQVHLEAEIEEPLRGMQIPKLSLQPL 487 L R S+ ++ + + E++++ +Y+ + MRY+ ++ +I+ L K+ LQPL Sbjct: 427 LFRASLSKGKELIPIATEVEHITNYLKIQQMRYQDKITFALDIDRGLYPYLTLKVLLQPL 486 Query: 488 IENSVFHGILPNKTAEGHIKVHVFTDSLQNHIVIEVSDDGVGLEEAALGTLQLHLLREES 547 +EN+++HGI K EG + + I +V DDG+G++++ + TL S Sbjct: 487 VENAIYHGI---KNKEGPGTITITGVRRDTRIEFQVKDDGIGMDQSKVETLLTSKEGTRS 543 Query: 548 TENIGLQNVWMRMKLLFGKAAQILLLSPPGEGMTIRITLP 587 ++G+ NV R++L FG + S PG G ++ + +P Sbjct: 544 RNSVGIANVHQRIQLYFGTEYGLSYASVPGSGTSVTLVIP 583 >B0P6G4.1 B0P6G4_9FIRM Putative uncharacterized protein Length = 603 Score = 171 bits (433), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 110/403 (27%), Positives = 202/403 (50%), Gaps = 18/403 (4%) Query: 193 KGVLLISMSNDQYQRQIENIQLGNRGSISLLTDDGMTIATTSRLEPKEDTGRVQNILKH- 251 +GVLL+ M+ ++ +N+ LG G + L+ G I P++ N+L Sbjct: 196 RGVLLVDMNYSGIEQLFKNVNLGGSGYVYLVDSAGEII-----YHPRQQL-LYSNLLSEN 249 Query: 252 ------WKELDRPNQFAVGSSIVSVKQTSTYDNWIVVSEIPSKELTASAEIIRRTVAYFL 305 + + F IV++K T Y W +V P ++ + + IR + + Sbjct: 250 NRAAVSYDDGSHVETFDGQERIVTIK-TVGYTGWKIVGVTPMQDAVSDSYAIRTFAVFII 308 Query: 306 GILVFLGALCVVGFGYQLYRPLQAVKRQVDAIKKGHFDARVTHFANNEIGDLGRMLNTMA 365 +FL + ++ P++ ++R V ++ G++D + + E+ LG+ + TM Sbjct: 309 LFTIFLMIFVNLFISSRIANPIKRLERSVKGLEGGNWDTEIAVGGSYEVAHLGKTIRTMV 368 Query: 366 VRIQDLLADLHDSEELKHKLEIRALQSQINPHFMYNTLNTIRMFAMMKDYEKINTLMGRL 425 +++ L+ D+ +E K K E ALQSQINPHF+YNTL++I + Y + T++ L Sbjct: 369 AQMRSLMDDIVAEQESKRKSEFDALQSQINPHFLYNTLDSIVWMIENERYPEAVTMVTAL 428 Query: 426 VALLRYSMENYEQTVQLQQELDYLADYVGLLNMRYKCQVHLEAEIEEPLRGMQIPKLSLQ 485 L R S+ + + + EL++ +Y+ + MRYK + + + + G+ KL +Q Sbjct: 429 ARLFRISLSKGKTIISVSDELEHARNYLTIQTMRYKNKFTVSVDAQPETLGLSTIKLIIQ 488 Query: 486 PLIENSVFHGILPNKTAEGHIKVHVFTDSLQNHIVIEVSDDGVGLEEAALGTLQLHLLRE 545 PL+EN+++HG+ + A+G ++ V + ++I+V D+G G+ TL R Sbjct: 489 PLLENAIYHGM---EFADGDGEICVRAYLADDDLIIDVEDNGCGIPADVCATLLTDETRV 545 Query: 546 EST-ENIGLQNVWMRMKLLFGKAAQILLLSPPGEGMTIRITLP 587 S IGL+NV R++L +G+ + ++S P G TIR+ LP Sbjct: 546 RSKGSGIGLRNVHQRIRLYYGEPYGLTIISEPDVGTTIRVRLP 588 >B1D7N6.1 B1D7N6_9BACL Integral membrane sensor signal transduction histidine kinase Length = 610 Score = 169 bits (429), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 121/462 (26%), Positives = 222/462 (48%), Gaps = 16/462 (3%) Query: 136 EAPAMLEDSPYRPLIEAYLSSGKANLFLDKHALPDLAILDSSTYYISRVPFDLYEDLKGV 195 E P SP +P +EA +S NL HA+ + ++ + I R P D ++ G Sbjct: 151 EWPTEHGSSP-KPFVEATHTSAHYNLDW-SHAVKEESVF-TLRRPIIRTPSD---EVIGY 204 Query: 196 LLISMSNDQYQRQIENIQLGNRGSISLLTDDGMTIATTSRLEPKEDTGRVQNILKHWKE- 254 L + + +D+ + + + + + ++ + + + E ++ +L +E Sbjct: 205 LSMDVKSDELNQICRQLTMSSEEQLYIIDRSRNFVCSVNGQEDQDRLKWTDQVLASKQEN 264 Query: 255 --LDRPNQFAVGSSIVSVKQTSTYDNWIVVSEIPSKELTASAEIIRRTVAYFLGILVFLG 312 + +Q G I T+ Y +W+VV ++P L SA IR + I + L Sbjct: 265 GVIKWQDQSFSGIVIYDTLSTN-YMDWVVVKQLPYSYLYESATAIRTINTSVIAIFMVLA 323 Query: 313 ALCVVGFGYQLYRPLQAVKRQVDAIKKGHFDARVTHFANNEIGDLGRMLNTMAVRIQDLL 372 + YQ +P++ + ++ ++ G+F+ V +EIG L R NTM I+DL+ Sbjct: 324 VIASFLVSYQFTKPIKRLIGHINQVQSGNFNVVVPVDRKDEIGILARRFNTMIQTIRDLI 383 Query: 373 ADLHDSEELKHKLEIRALQSQINPHFMYNTLNTIRMFAMMKDYEKINTLMGRLVALLRYS 432 + E ++RA+Q+QINPHF+YN L +I A+ K+ TL+ + ++RY+ Sbjct: 384 NSEYRLEIANKTNQLRAMQAQINPHFLYNALQSIGTLALHAGAPKVYTLITSIAKMMRYN 443 Query: 433 MENYEQTVQLQQELDYLADYVGLLNMRYKCQVHLEAEIEEPLRGMQIPKLSLQPLIENSV 492 M E V EL++ Y+ L R+ Q+ + +I+ +Q+PK+ LQPL+EN Sbjct: 444 MNTSESIVPFSMELNHAKAYLELQQQRFNEQLTVHYDIDPASLSVQVPKMLLQPLVENYF 503 Query: 493 FHGILPNKTAEGHIKVHVFTDSLQNHIVIEVSDDGVGLEEAALGTLQLHLLRE-----ES 547 HG G +++ + + I + D+G G++ L L+ L R E Sbjct: 504 KHG-YETSGRSGVLRLFSEVTDDGSWLTIRIEDNGSGMDPDKLRELRQLLFRSTGALLEE 562 Query: 548 TENIGLQNVWMRMKLLFGKAAQILLLSPPGEGMTIRITLPIE 589 ++IG+ NVWMR+KL + + A++ + S P G T+ + +P++ Sbjct: 563 QKSIGISNVWMRLKLYYNEEAEMSIDSSPSGGFTVTLRIPVQ 604 >B1DBG2.1 B1DBG2_9BACL Histidine kinase internal region Length = 595 Score = 169 bits (428), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 146/566 (25%), Positives = 267/566 (47%), Gaps = 44/566 (7%) Query: 44 VEKQVNRLNAQLVNQVVDRIELTMTRLRELS---EQYSRISSIQSALVSPS-AQYFEEVV 99 +E+QV + Q++ QV I+ M L LS QY I + P A +E+ Sbjct: 47 MEEQVGKYQLQMLKQVTLNIDTYMNELNRLSLMPYQYQEILDFLATSRKPGEALSLQEID 106 Query: 100 RKKELIS-VLSNASAVIGNVEGLQVYSAITGEVLSSTEAPAMLEDSPYRPLIE-----AY 153 +S V N ++ G+ ++ GE +S +L +S Y + + Sbjct: 107 DLNNFVSKVFLNGRV---DIMGISLF----GEHGASY---VVLPESQYMTTYQLGGNTEW 156 Query: 154 LSSGKANL----FLDKHALPDLAILDSSTYYISR--VPFDLYEDLKGVLLISMSNDQYQR 207 L K F+ H + + + I+R FD + L G ++I + + ++ Sbjct: 157 LEKAKGRFGQPTFITTHEVKSTSGTAYQVFSIARELRSFDSGDTL-GYIVIDIDPAEVRK 215 Query: 208 QIENIQLGNRGSISLLTDDGMTIATTSRLEPKEDTGRVQNILKHWKELDRPNQFAVGSSI 267 + + LG++ S+ MT + + KE T + +++ + + G S+ Sbjct: 216 LLSQVSLGSKESLY------MTDSAGDLVLRKEKTA-IYPVIEGLSDEGVSHHKIDGKSL 268 Query: 268 VSVKQTSTYDNWIVVSEIPSKELTASAEIIRRTVAYFLGILVFLGALCVVGFGYQLYRPL 327 + +S W V +P L + ++R ++ GI V L L V +++ PL Sbjct: 269 LVAHVSSEVTGWTTVGVVPVSVLMKDSLVVRNSIILIGGICVGLAVLLSVFIAFRITSPL 328 Query: 328 QAVKRQVDAIKKGHFDARVTHFANNEIGDLGRMLNTMAVRIQDLLADLHDSEELKHKLEI 387 + ++ + +++G +E+G LG N M + +L L+++E + EI Sbjct: 329 RMLRSLMRKVERGDLKVSFPVRQWDEVGQLGNAFNMMVSHLSELGYRLYETEIREKDAEI 388 Query: 388 RALQSQINPHFMYNTLNTIRMFAMMKDYEKINTLMGRLVALLRYSMENYEQTVQLQQELD 447 ALQS+INPHF+YNTL +I M+A ++ ++ T+ L LLRYS+ ++TV L+ ELD Sbjct: 389 AALQSKINPHFLYNTLGSISMYAEVEGNREVVTMTNNLSRLLRYSLSGRKETVTLRDELD 448 Query: 448 YLADYVGLLNMRYKCQVHLEAEIEEPLRGMQIPKLSLQPLIENSVFHGILPNKTAEGHIK 507 ++ Y+ + MRY ++ E++E L G + L +QP++EN++ HG L EG I+ Sbjct: 449 HVKGYMTIQKMRYDDRIDFRLEVDESLYGCPVIPLMIQPIVENAINHG-LDKGIGEGRIQ 507 Query: 508 VHVFTDSLQNHIVIEVSDDGVGLEEAALGTL-----QLHLLREESTENIGLQNVWMRMKL 562 + + + Q ++I + DDG+G+ L + ++H L T GL NV R++L Sbjct: 508 LSCYQE--QGMLMIVIEDDGIGMTSEQLSAMRKRMDKIHDL--GGTSGNGLMNVHRRIRL 563 Query: 563 LFGKAAQILLLSPPGEGMTIRITLPI 588 +G+ + L S P +G+ + +T+PI Sbjct: 564 HYGEQYGLQLESMPFQGLKVILTMPI 589 >B3K5A3.1 B3K5A3_9BACI Histidine kinase internal region Length = 592 Score = 169 bits (427), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 155/574 (27%), Positives = 266/574 (46%), Gaps = 68/574 (11%) Query: 44 VEKQVNRLNAQLVNQVVDRIELTMTRLRELSEQYSRISSIQSALVSPSAQYFEEVVRKKE 103 VE+QV+++ + + QV D++ + +L + S + L ++ ++ KE Sbjct: 41 VEEQVSKVASLTITQVSDKLNMFFKKLDDSSMMVLNSKVVHGILEDQDISKYDLTLKVKE 100 Query: 104 LISVLSNASAVIGNVEGLQVY--------SAITGEVLSSTEAPAMLEDSPYRPLIEAYLS 155 +L+ S +I + E L VY S ++ + L S P + YR ++EA Sbjct: 101 GKDLLT--SIMINSPEILDVYVFDVQRNNSVLSADSLMSI--PDQWDSPWYRAILEA--- 153 Query: 156 SGKANLFLDKHALPDLAILDSS-----TYYISRV--PFDLYEDLKGVLLISMSNDQYQRQ 208 +G+A F L D + L + + + R +D E + GV+ I + D + Sbjct: 154 NGQAVWF----GLSDTSYLKQTGMGFPVFGLGRAIRSWDTGE-IVGVMFIEIMGDVLIDE 208 Query: 209 IENIQLGNRGSISLLTD--------DGMTIATTSRLEPKEDTGRVQNILKHWKELDRPNQ 260 + ++Q G+ G + + D D SR+ K +G + L + K L P++ Sbjct: 209 LNHVQFGDTGYMYVANDENRYFYHPDPSMYGKQSRI--KLPSGLTEYNLNNNKTLMIPSR 266 Query: 261 FAVGSSIVSVKQTSTYDNWIVVSEIPSKELTASAEIIRRTVAYFLGILVFLGALCVVGFG 320 G W VV +P KELTA + IR + +VF L +G G Sbjct: 267 LNNG--------------WHVVGMVPLKELTADSASIRSFTVW----IVFGSILAAIGIG 308 Query: 321 YQLYR----PLQAVKRQVDAIKKGHFDARVTHFANNEIGDLGRMLNTMAVRIQDLLADLH 376 Y + R PL + R + + G R + +EIG LGR N M +I L+ + Sbjct: 309 YFMTRRIGNPLVQLSRLMRRSEAGDLSVRSKNVGPSEIGQLGRSFNKMIEQIDLLIRRIA 368 Query: 377 DSEELKHKLEIRALQSQINPHFMYNTLNTIRMFAMMKDYEKINTLMGRLVALLRYSMENY 436 E K K EIRAL+ QINPHF+YNTLN+IR A + ++ + LV LL S+E Sbjct: 369 AEESEKKKAEIRALRYQINPHFLYNTLNSIRWMAKLNRTNDVDRSVTALVHLLEGSLERN 428 Query: 437 EQTVQLQQELDYLADYVGLLNMRYKCQVHLEAEIEEPLRGMQIPKLSLQPLIENSVFHGI 496 ++L EL+ L Y+ + N RY + L + E + + +P++ LQP++EN++FHGI Sbjct: 429 GVFIRLGDELELLRKYMIIQNYRYDHPIELRIDCPEEMEDLHVPRMLLQPIVENAIFHGI 488 Query: 497 LPNKTAEGHIKVHVFTDSLQNHIVIEVSDDGVGLEEAALGTL----QLHLLREESTENIG 552 P EG + + + Q +++ + D+G+G++ + L Q H ++ +IG Sbjct: 489 AP--LDEGGV-IQIRITLQQQDVMVRIEDNGIGIKPERIKGLLSYEQDH--SKQGMTHIG 543 Query: 553 LQNVWMRMKLLFGKAAQILLLSPPGEGMTIRITL 586 L++V ++L +G + + S G G + +T Sbjct: 544 LRHVHQTVQLYYGSRYGVWVESTEGGGTRVTVTF 577 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.134 0.372 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 3,026,637,887 Number of extensions: 120488649 Number of successful extensions: 378786 Number of sequences better than 1.0e-05: 2128 Number of HSP's gapped: 375634 Number of HSP's successfully gapped: 2130 Length of query: 601 Length of database: 3,060,696,203 Length adjustment: 142 Effective length of query: 459 Effective length of database: 1,722,912,073 Effective search space: 790816641507 Effective search space used: 790816641507 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 134 (56.2 bits)