BLASTP 2.2.18 [Mar-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Query= 0443.0016.p (247 letters) Database: pfamseq 9,421,015 sequences; 3,060,696,203 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value B3K577.1 B3K577_9BACI Regulatory protein IclR 322 2e-86 B1D8S6.1 B1D8S6_9BACL Transcriptional regulator, IclR family 278 3e-73 C0ZHQ6.1 C0ZHQ6_BREBN Transcriptional regulator 275 2e-72 Q67LC3.1 Q67LC3_SYMTH Transcriptional regulator 164 6e-39 C1PV49.1 C1PV49_ALIAC Transcriptional regulator, IclR family 157 6e-37 >B3K577.1 B3K577_9BACI Regulatory protein IclR Length = 246 Score = 322 bits (824), Expect = 2e-86, Method: Compositional matrix adjust. Identities = 163/246 (66%), Positives = 191/246 (77%) Query: 1 VEDRKLTVRAVERALDILLCFTQENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNE 60 +EDRKLTVRAVERALDIL+CFT++ +L+LTEI+S I LHKSTVHRLLTTLE+KGF++RN+ Sbjct: 1 MEDRKLTVRAVERALDILMCFTKDGELALTEISSLIGLHKSTVHRLLTTLEDKGFVVRNK 60 Query: 61 ATEKYRLGIRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQ 120 TEKYRLG++IWELS HL D+PA L PAME LRDRLGET SLYLRD +R+RIQAVQ Sbjct: 61 ETEKYRLGLKIWELSMHLSQSDDPAIRLQPAMEALRDRLGETVSLYLRDGSDRLRIQAVQ 120 Query: 121 SRQAIRRVAQIGARLPLSVGASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEI 180 S Q IRRVAQ+G RLPLSVGASSKVL A+AP+ Q LL P+WPEAVDK AY QL EI Sbjct: 121 SNQGIRRVAQVGVRLPLSVGASSKVLVAFAPEADQEELLNAPDWPEAVDKNAYRQQLAEI 180 Query: 181 IRRGYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAA 240 + GYA S EEREP VAAALS+SGPV+RLS E L ++A +L E A Sbjct: 181 LENGYAISIEEREPGAAAVSVPIFDRSGRVAAALSMSGPVTRLSAETLREHAPILMEAAR 240 Query: 241 EMGLMM 246 EMG+M+ Sbjct: 241 EMGMMI 246 >B1D8S6.1 B1D8S6_9BACL Transcriptional regulator, IclR family Length = 247 Score = 278 bits (711), Expect = 3e-73, Method: Compositional matrix adjust. Identities = 138/246 (56%), Positives = 178/246 (72%) Query: 1 VEDRKLTVRAVERALDILLCFTQENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNE 60 +E+ K VRAVERALDILLCFT+ DL+++EIA K+ LHKSTVHR+L TLE +GF+ R+ Sbjct: 1 MEEGKSNVRAVERALDILLCFTEGTDLAMSEIADKVGLHKSTVHRMLATLENRGFVERDP 60 Query: 61 ATEKYRLGIRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQ 120 ++E+Y LG+R+WELS HL + D+ + + P ME+LRDRLGET S+Y+RD ERVRIQAVQ Sbjct: 61 SSERYHLGMRMWELSAHLSSSDDQSVIWQPEMERLRDRLGETVSIYVRDGSERVRIQAVQ 120 Query: 121 SRQAIRRVAQIGARLPLSVGASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEI 180 S Q +RRVA +GARLPL GASSKVL AY+ + VQ ++ DP W A+D Y QL+EI Sbjct: 121 SNQPVRRVAPVGARLPLYAGASSKVLIAYSDRFVQEQIFGDPAWLLAIDLDQYKQQLEEI 180 Query: 181 IRRGYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAA 240 ++GYATSFEEREP VAAALS+SGP SRL+ + + +Y+ VL E A Sbjct: 181 AQQGYATSFEEREPGVAALAAPIFNRHGKVAAALSVSGPSSRLTMDTMSEYSTVLIEFAK 240 Query: 241 EMGLMM 246 MG M+ Sbjct: 241 RMGTMI 246 >C0ZHQ6.1 C0ZHQ6_BREBN Transcriptional regulator Length = 248 Score = 275 bits (703), Expect = 2e-72, Method: Compositional matrix adjust. Identities = 138/245 (56%), Positives = 178/245 (72%) Query: 2 EDRKLTVRAVERALDILLCFTQENDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEA 61 E++K VRAV+RALDILLCFT DL L+EIAS++SLHKSTVHRLL TLE KGFL+R+ Sbjct: 3 EEQKANVRAVDRALDILLCFTDATDLGLSEIASRLSLHKSTVHRLLATLENKGFLIRDVQ 62 Query: 62 TEKYRLGIRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQS 121 TEKYRLG R+WELS +L D+PA LLLP ME+LRD + ET SLY+RD ER+R+QAVQS Sbjct: 63 TEKYRLGFRVWELSANLSQNDDPATLLLPEMERLRDLVEETISLYVRDGNERIRVQAVQS 122 Query: 122 RQAIRRVAQIGARLPLSVGASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEII 181 +Q IRRVA IGAR+PL+VGASSKVL AYA + +++DPNWP+ V+K +++ QL +I Sbjct: 123 KQPIRRVAPIGARMPLAVGASSKVLVAYAEPFILQEVISDPNWPDFVNKESFIEQLDQIR 182 Query: 182 RRGYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAAE 241 ++G+ATS EERE + A+++ SGP +RL+ E + YA + E A Sbjct: 183 KQGFATSVEERELGTAAVAVPIFNRNGQLVASIAASGPSNRLTPEKMSQYAPYIMEAAYR 242 Query: 242 MGLMM 246 MG MM Sbjct: 243 MGKMM 247 >Q67LC3.1 Q67LC3_SYMTH Transcriptional regulator Length = 236 Score = 164 bits (415), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 99/238 (41%), Positives = 140/238 (58%), Gaps = 4/238 (1%) Query: 11 VERALDILLCFTQE-NDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATEKYRLGI 69 +ERALD+LLCF E L +T+IA K+ L+KSTVHR+L LE +GF+ R+ AT +Y LG+ Sbjct: 1 MERALDVLLCFAGERGGLGVTQIAEKLGLYKSTVHRILAALESRGFVRRDPATGRYHLGL 60 Query: 70 RIWELS-THLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSRQAIRRV 128 R EL+ +L + D P + L M +LRD ET SLY+RD ERVR+Q + +RRV Sbjct: 61 RALELAQVYLSSGDLP-TIALGEMLQLRDLAQETVSLYVRDGAERVRVQRAEGPLTVRRV 119 Query: 129 AQIGARLPLSVGASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEIIRRGYATS 188 +G RLPL +GAS KVL A+ P E + R+L D P D+ A +L E +G+A S Sbjct: 120 VGLGERLPLYLGASGKVLLAWCPPEERARIL-DAQLPAGFDRTALEARLAEAREQGWALS 178 Query: 189 FEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAAEMGLMM 246 EERE AAL++SGPVSR + + + ++ + A +G+ + Sbjct: 179 LEEREEGVASVAAPVIDRAGRCVAALAISGPVSRFTDDRVAMFSRAVQATARSIGMKL 236 >C1PV49.1 C1PV49_ALIAC Transcriptional regulator, IclR family Length = 252 Score = 157 bits (398), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 97/239 (40%), Positives = 133/239 (55%), Gaps = 1/239 (0%) Query: 5 KLTVRAVERALDILLCFTQE-NDLSLTEIASKISLHKSTVHRLLTTLEEKGFLLRNEATE 63 + TVRAVERALDILL FT SL+EIA LHKSTVHRLL L++KGF+ R ++ Sbjct: 8 QTTVRAVERALDILLLFTHSPRAWSLSEIARATGLHKSTVHRLLLALQQKGFVRRESESD 67 Query: 64 KYRLGIRIWELSTHLPTLDEPAALLLPAMEKLRDRLGETASLYLRDDLERVRIQAVQSRQ 123 +Y LG ++ L + D + P + +LRD ET SLY+R+ LER+RI AV+S Q Sbjct: 68 RYVLGWSLYGLGANAALHDRWSDAAKPILRRLRDETNETVSLYVRNGLERIRILAVESLQ 127 Query: 124 AIRRVAQIGARLPLSVGASSKVLAAYAPQEVQTRLLADPNWPEAVDKGAYLGQLQEIIRR 183 IR VA +G R PL++GAS KVL A++ V P V + QL+ I R Sbjct: 128 PIRNVASVGERYPLTIGASGKVLLAFSNSAVIEAACHPDRLPNGVRQVDLRQQLEAIRRE 187 Query: 184 GYATSFEEREPXXXXXXXXXXXXXXTVAAALSLSGPVSRLSREMLEDYAVVLAENAAEM 242 GYA S +ER+ + A+++SGPV R++ + + D L A E+ Sbjct: 188 GYALSRQERDAGAAAIAAPVLNEDGSCLYAIAVSGPVERMTEDKMRDMVTPLKRAAEEL 246 Database: pfamseq Posted date: Aug 5, 2010 3:22 PM Number of letters in database: 3,060,696,203 Number of sequences in database: 9,421,015 Lambda K H 0.318 0.132 0.362 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Sequences: 9421015 Number of Hits to DB: 1,145,139,979 Number of extensions: 39975510 Number of successful extensions: 148692 Number of sequences better than 1.0e-05: 2545 Number of HSP's gapped: 147477 Number of HSP's successfully gapped: 2546 Length of query: 247 Length of database: 3,060,696,203 Length adjustment: 132 Effective length of query: 115 Effective length of database: 1,817,122,223 Effective search space: 208969055645 Effective search space used: 208969055645 Neighboring words threshold: 11 Window for multiple hits: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 129 (54.3 bits)